@misc{11546,
author = {{Trilling-Haasler, Marc and Katsch, Linda and Schneider, Jan}},
location = {{Kaiserslautern}},
title = {{{PETauthent}}},
year = {{2023}},
}
@misc{13650,
author = {{Uhlendorff, Selina and Hernández Rodríguez, Tanja and Frahm, Björn and Pein-Hackelbusch, Miriam}},
location = {{Lemgo, Germany}},
title = {{{Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities}}},
year = {{2023}},
}
@misc{9627,
author = {{Ramm, Selina and Fulek, Ruwen and Eberle, Veronika Anna and Kiera, Christian and Odefey, Ulrich and Pein-Hackelbusch, Miriam}},
location = {{Rosenberg}},
title = {{{Compression Density as an Alternative to Identify an Optimal Moisture Content for High Shear Wet Granulation as an Initial Step for Spheronisation}}},
year = {{2023}},
}
@misc{10201,
author = {{Hernández Rodriguez, Tanja and Ramm, Selina and Lange-Hegermann, Markus and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{A systematic, model-based workflow for risk-based decision making in upstream development}}},
year = {{2023}},
}
@misc{10216,
abstract = {{Wet granulation is a frequent process in the pharmaceutical industry. As a starting point for numerous dosage forms, the quality of the granulation not only affects subsequent production steps but also impacts the quality of the final product. It is thus crucial and economical to monitor this operation thoroughly. Here, we report on identifying different phases of a granulation process using a machine learning approach. The phases reflect the water content which, in turn, influences the processability and quality of the granule mass. We used two kinds of microphones and an acceleration sensor to capture acoustic emissions and vibrations. We trained convolutional neural networks (CNNs) to classify the different phases using transformed sound recordings as the input. We achieved a classification accuracy of up to 90% using vibrational data and an accuracy of up to 97% using the audible microphone data. Our results indicate the suitability of using audible sound and machine learning to monitor pharmaceutical processes. Moreover, since recording acoustic emissions is contactless, it readily complies with legal regulations and presents Good Manufacturing Practices.}},
author = {{Fulek, Ruwen and Ramm, Selina and Kiera, Christian and Pein-Hackelbusch, Miriam and Odefey, Ulrich}},
booktitle = {{Pharmaceutics}},
issn = {{1999-4923 }},
keywords = {{wet granulation, acoustic classification, machine learning, convolutional neural networks}},
number = {{8}},
publisher = {{MDPI}},
title = {{{A machine learning approach to qualitatively evaluate different granulation phases by acoustic emissions}}},
doi = {{https://doi.org/10.3390/pharmaceutics15082153}},
volume = {{15}},
year = {{2023}},
}
@misc{10245,
author = {{Wefing, Patrick and Schneider, Jan}},
booktitle = {{Brauwelt international : journal for the brewing and beverage industry }},
issn = {{0934-9340}},
pages = {{224--227}},
publisher = {{Hans Carl Verlag}},
title = {{{FAN measurement during mashing}}},
volume = {{IV}},
year = {{2023}},
}
@misc{10326,
abstract = {{In the food industry, and especially in wines as products thereof, ethanol and sulfur dioxide play an equally important role. Both substances are important wine quality characteristics as they influence the taste and odor. As both substances comprise volatile matter, electronic noses should be applicable to discriminate the different qualities of wines. Our study investigates the influence of alcohol and sulfur dioxide on the discrimination ability of wines (especially those of the same grape variety) using two different electronic nose systems. One system is equipped with metal oxide sensors and the other with quartz crystal microbalance sensors. Contrary to indications in literature, where the alcohol content is discussed to have a large influence on e-nose results, it was shown that a difference of 1 % ethanol was not sufficient to allow accurate discrimination using Linear Discriminant Analysis by any system. On the positive side, the analyzed concentrations of ethanol (about 12 %) did not superimpose other volatile information. So difference in sulfur dioxide content gave an accuracy for sample discrimination of up to 90.6 % with MOS nose. Thus, we are so far partially able to discriminate wines with electronic noses based on their volatile imprint.}},
author = {{Wörner, Julius and Dörksen, Helene and Pein-Hackelbusch, Miriam}},
booktitle = {{2023 IEEE 21st International Conference on Industrial Informatics (INDIN)}},
keywords = {{Ethanol, Pipelines, Metals, Nose, Electronic noses, Sensor systems, Sensors, Quartz crystals, Linear discriminant analysis, Sulfur}},
location = {{Lemgo}},
title = {{{Key Indicators for the Discrimination of Wines by Electronic Noses}}},
doi = {{https://doi.org/10.1109/INDIN51400.2023.10217912}},
year = {{2023}},
}
@misc{10327,
abstract = {{Wound infections are a major problem worldwide, both for the healthcare system and for patients affected. Currently available diagnostic methods to determine the responsible germs are time-consuming and costly. Wound infections are mostly caused by various bacteria, which in turn produce volatile organic compounds. From clinical experience, we know that depending on the bacteria involved, a specific odor impression can be expected. For this reason, we hypothesized that electronic noses, i.e., non-invasive electronic sensors for the detection of volatile organic compounds, are applicable for diagnostic purposes. By providing a comprehensive overview of the state-of-research, we tested our hypothesis. In particular, we addressed three overarching questions: 1) which sensor technologies are suitable for the diagnosis of wound infections and why? 2) how must the (biological) sample be prepared and presented to the measurement system? 3) which machine learning methods and algorithms have already proven successful for the classification of microorganisms? The corresponding articles have critically been reviewed and are discussed particularly in the context of their potential for clinical diagnostics. In summary, it can already be stated today that the use of electronic noses for the detection of bacteria in wound infections is a very interesting, fast and non-invasive method. However, reliable clinical studies are still missing and further research is necessary.}},
author = {{Wörner, Julius and Moelleken, Maurice and Dissemond, Joachim and Pein-Hackelbusch, Miriam}},
booktitle = {{Frontiers in Sensors}},
issn = {{2673-5067}},
publisher = {{Frontiers Media}},
title = {{{Supporting wound infection diagnosis: advancements and challenges with electronic noses}}},
doi = {{https://doi.org/10.3389/fsens.2023.1250756}},
volume = {{4}},
year = {{2023}},
}
@misc{10554,
author = {{Tholen, Janna and Schulze Althoff, Gereon and Voss, A. and Upmann, Matthias}},
booktitle = {{63. Arbeitstagung des Arbeitsgebietes Lebensmittelsicherheit und Verbraucherschutz 2023}},
location = {{Garmisch-Partenkirchen}},
publisher = {{Verlag der DVG Service GmbH, Gießen}},
title = {{{Automatische Kontaminationserkennung auf Schweineschlachtkörpern mittels Kamerasystem}}},
year = {{2023}},
}
@misc{10787,
abstract = {{Cyber-physical production systems have emerged with the rise of Industry 4.0 in different industrial fields. Especially the food sector, where inhomogeneous input products like beer/yeast suspensions with different qualities and properties have yet slowed down automation, has potential for this evolution. This contribution presents optimization methods for a dynamical cross-flow filtration plant which is driven by an advanced control concept in combination with data driven product monitoring via inline near infrared spectroscopy (NIR) in order to improve energy savings and filtration performance. Using a hierarchical control and optimization structure, the non stationary batch process is steered towards a high production rate with low energy consumption for a variety of different input products.}},
author = {{Tebbe, Jörn and Pawlik, Thomas and Trilling-Haasler, Marc and Löbner, Jannis and Lange-Hegermann, Markus and Schneider, Jan}},
booktitle = {{2023 IEEE 21st International Conference on Industrial Informatics (INDIN)}},
editor = {{Jasperneite, Jürgen and Wisniewski, Lukasz and Fung Man, Kim}},
isbn = {{978-1-6654-9314-7 }},
issn = {{1935-4576}},
keywords = {{Spectroscopy, Production systems, Filtration, Velocity control, Optimization methods, Cyber-physical systems, Nonhomogeneous media}},
location = {{Lemgo}},
pages = {{1--7}},
publisher = {{IEEE}},
title = {{{Holistic optimization of a dynamic cross-flow filtration process towards a cyber-physical system}}},
doi = {{10.1109/INDIN51400.2023.10217913}},
year = {{2023}},
}
@misc{10788,
abstract = {{For process monitoring, an adequate data preprocessing is crucial to link accessible inline process data with offline measured target variables. Literature, however, does not provide systematic preprocessing strategies. The effects of five different preprocessing strategies on data from a Dielectric Spectroscopy system applied to the Viable Cell Density (VCD) of a mammalian cell cultivation were thus evaluated. Single-frequency measurements are typically used to model the VCD over the growth phase using linear regression or the Cole-Cole model and served as a reference. As multi-frequency measurement is promising to model the VCD beyond the growth phase using Partial Least Squares Regression (PLSR), we further aimed to determine, whether replacing linear regression by PLSR shows comparable modeling performance. All five preprocessing strategies led to comparable results. Exemplary, when using capacitance values at a frequency of 3347 kHz, linear regression resulted in a R2 of 0.90 and a standard deviation of 0.4 % on average. Both normalization techniques had the same positive effect on the results of PLSR. The order of smoothing and normalization was irrelevant for both regression methods. Comparing the results of linear regression and PLSR, the latter obtained on average 9 % better results. Therefore, we concluded that PLSR is preferable over linear regression and is potentially suitable to model the VCD beyond the growth phase, which is suggested to be investigated based on more data sets.}},
author = {{Ramm, Selina and Hernández Rodriguez, Tanja and Frahm, Björn and Pein-Hackelbusch, Miriam}},
booktitle = {{2023 IEEE 21st International Conference on Industrial Informatics (INDIN)}},
editor = {{Jasperneite, Jürgen and Wisniewski, Lukasz and Fung Man, Kim}},
isbn = {{978-1-6654-9314-7}},
issn = {{1935-4576}},
keywords = {{Spectroscopy, Smoothing methods, Systematics, Phase measurement, Linear regression, Data models, Dielectric measurement}},
location = {{Lemgo}},
pages = {{1--6}},
publisher = {{IEEE}},
title = {{{Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities}}},
doi = {{10.1109/INDIN51400.2023.10218012}},
year = {{2023}},
}
@misc{10995,
author = {{Tholen, Janna and Mohr, Jessica and Bruns, Michael and Schulze Althoff, Gereon and Upmann, Matthias}},
location = {{Berlin}},
title = {{{Auswirkung verschiedener Kontaminationsarten auf den Oberflächenkeimgehalt von Schweineschlachtkörpern}}},
year = {{2023}},
}
@misc{10998,
author = {{Tholen, Janna and Upmann, Matthias}},
location = {{Lemgo}},
title = {{{Erfassung von Schlachtkörperkontaminationen mittels Videobildanalyse}}},
year = {{2023}},
}
@misc{11105,
author = {{Psiuk, Marta and Wilhelm, Patrick and Müller, Ulrich and Gebhardt, Ronald}},
keywords = {{rheology, oligomere, flow curves, activation energy, temperature sweep, temperature dependence, arrhenius plot}},
location = {{Bochum}},
title = {{{Die Bedeutung der Knäuelbildung bei künstlichen Oligomeren für kinetische Vorgänge wie das Fließen und die Übertragung der Erkenntnisse auf Lebensmittelprozesse}}},
year = {{2023}},
}
@misc{11106,
author = {{Barakat, Bayan and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich}},
keywords = {{essential oil, oregano, steam distillation, vacuum, temperature impact, oil glandular}},
location = {{Bochum}},
title = {{{Untersuchung des Drüsenschuppenaufschlusses bei Oregano-Pflanzen in Abhängigkeit vom Druck und der Temperatur mittels einer modifizierten Sichtzellen-Apparatur}}},
year = {{2023}},
}
@misc{11107,
author = {{Bekonda, Euphinette Amba and Barakat, Bayan and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich}},
keywords = {{essential oil, oregano, steam distillation, vacuum, temperature impact, oil glandular}},
location = {{Freising}},
title = {{{Untersuchung des Berstverhaltens von Drüsenschuppen der Ätherisch-Ölpflanze Oregano im Unterdruck}}},
year = {{2023}},
}
@misc{11109,
author = {{Blome, André and Luttmann, Mario and Jekle, Mario and Frahm, Björn and Müller, Ulrich}},
location = {{Bochum}},
title = {{{Untersuchung der räumlichen Verteilung von viskoelastischen Kenngrößen während der Weizenteigbereitung}}},
year = {{2023}},
}
@misc{11110,
author = {{Blome, André and Luttmann, Mario and Segermann, Jan and Jekle, Mario and Frahm, Björn and Müller, Ulrich}},
location = {{Bochum}},
title = {{{Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung}}},
year = {{2023}},
}
@misc{9697,
abstract = {{Continuous processes offer more environmentally friendlier beer production compared to the batch production. However, the continuous production of mashing has not become state-of-the-art in the brewing industry. The controllability and flexibility of this process still has hurdles for practical implementation, but which are necessary to react to changing raw materials. Once overcome, a continuous mashing can be efficiently adapted to the raw materials. Both mean residence time and temperature were investigated as key parameters to influence the extract and fermentable sugar content of the wort. The continuous mashing process was implemented as continuous stirred tank reactor (CSTR) cascade consisting of mashing in (20°C), protein rest (50°C), β-amylase rest (62-64°C), saccharification rest (72°C) and mashing out (78°C). Two different temperature settings for the β-amylase rest were investigated with particular emphasis on fermentable sugars. Analysis of Variance (ANOVA) and a post-hoc analysis showed that the mean residence time and temperature settings were suitable control parameters for the fermentable sugars. In the experimental conditions, the most pronounced effect was with the β-amylase rest. These results broaden the understanding of heterogenous CSTR mashing systems about assembly and selection of process parameters}},
author = {{Wefing, Patrick and Trilling, Marc and Gossen, Arthur and Neubauer, Peter and Schneider, Jan}},
booktitle = {{Journal of The Institute of Brewing}},
keywords = {{ontinuous mashing, continuous stirred tank reactor, mean residence time, fermentable sugar}},
number = {{1}},
pages = {{1--23}},
publisher = {{Wiley}},
title = {{{A continuous mashing plant controlled by mean residence time}}},
doi = {{10.58430/jib.v129i1.7}},
volume = {{129}},
year = {{2023}},
}
@misc{12483,
author = {{Blome, André and Luttmann, Mario and Segermann, Jan and Jekle, Mario and Frahm, Björn and Müller, Ulrich}},
location = {{Lemgo, Germany}},
title = {{{Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung}}},
year = {{2023}},
}
@misc{12485,
author = {{Luttmann, Mario and Blome, André and Jekle, Mario and Frahm, Björn and Müller, Ulrich}},
location = {{Lemgo, Germany}},
title = {{{Teig 4.0 - Promotionsthemen}}},
year = {{2023}},
}
@misc{12897,
abstract = {{Glove occlusion might enhance skin sensitivity to a subsequent detergent challenge (occlusion effect). Thus, some skin protection creams (PC) claim to protect against this effect of occlusion, and are recommended to be used before wearing liquid‐proof gloves.ObjectivesTo evaluate the effect of PC applied prior to glove occlusion on the ‘occlusion effect’—refers to increased susceptibility of the skin to a model detergent.MethodsOne hundred and eleven volunteers were enrolled in a single‐blind, randomized study. Seven PCs were applied before glove occlusion over 7 days (D1–D7). After sodium lauryl sulphate (SLS) challenge, we compared the irritation between the areas treated with PC and occlusion alone. Clinical scoring and bioengineering methods (capacitance, transepidermal water loss [TEWL], and colourimetry [erythema]) were used to quantify the irritant reactions.ResultsAfter 1 week of occlusion and PC application, we did not observe significant changes in TEWL, nor in erythema, whereas skin hydration raised in three cream‐treated areas. On day 10, after a challenge with SLS, some products significantly aggravated the skin irritation as compared to occlusion alone.ConclusionsThe ‘occlusion effect’—shown as higher skin susceptibility to a model detergent—was not mitigated by PCs when applied prior to glove occlusion. On the contrary, some PCs might have negative effects on skin barrier function and augment such sensitivity.}},
author = {{Gina, Michal and Wichert, Katharina and Kutz, Gerd and Brüning, Thomas and Fartasch, Manigé}},
booktitle = {{Contact dermatitis : environmental and occupational dermatitis}},
issn = {{1600-0536}},
keywords = {{barrier disturbance, glove occlusion, irritant contact dermatitis, irritation, non-invasive measuring methods, occupational contact dermatitis, skin barrier disturbance, skin protective cream, wet work.}},
number = {{5}},
pages = {{372--382}},
publisher = {{Wiley}},
title = {{{Applying skin protective cream and the wearing of gloves?—A randomized controlled experimental study}}},
doi = {{10.1111/cod.14287}},
volume = {{88}},
year = {{2023}},
}
@misc{12940,
abstract = {{There are limited data on Lyme borreliosis (LB), a tick-borne disease caused by the Borrelia burgdorferi sensu lato complex, in horses. Seropositivity is not necessarily associated with clinical disease. Data on seropositivity against Borrelia burgdorferi and Anaplasma phagocytophilum in German horses are sparse. Therefore, serum samples from horses (n = 123) suspected of having Lyme borreliosis and clinically healthy horses (n = 113) from the same stables were tested for specific antibodies against Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum. The samples were screened for antibodies against Borrelia burgdorferi (ELISA and an IgG line immunoblot assay). Furthermore, the samples were examined for antibodies against B. burgdorferi and Anaplasma phagocytophilum with a validated rapid in-house test (SNAP® 4Dx Plus® ELISA). The clinical signs of suspect horses included lameness (n = 36), poor performance (n = 19), and apathy (n = 12). Twenty-three percent (n = 26) of suspect horses and 17% (n = 18) of clinically healthy horses were seropositive for having a Borrelia burgdorferi sensu lato infection (p = 0.371), showing that the detection of specific antibodies against B. burgdorferi alone is not sufficient for a diagnosis of equine LB. Anaplasma phagocytophilum seropositivity and seropositivity against both pathogens was 20%/6% in suspect horses and 16%/2% in the clinically healthy population, showing only minor differences (p = 0.108). Unspecific testing for antibodies against B. burgdorferi without clinical suspicion of Lyme borreliosis is not recommended since the clinical relevance of seropositivity against Borrelia burgdorferi sensu lato remains to be elucidated.}},
author = {{Gehlen, Heidrun and Inerle, Katharina and Bartel, Alexander and Stöckle, Sabita Diana and Ulrich, Sebastian and Briese, Beatrice and Straubinger, Reinhard K.}},
booktitle = {{Animals}},
issn = {{2076-2615}},
keywords = {{equine Lyme borreliosis, equine granulocytic anaplasmosis, seroprevalence, co-infection}},
number = {{12}},
publisher = {{MDPI AG}},
title = {{{Seroprevalence of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum Infections in German Horses}}},
doi = {{10.3390/ani13121984}},
volume = {{13}},
year = {{2023}},
}
@misc{12941,
abstract = {{Stachybotrys chartarum (Hypocreales, Ascomycota) is a toxigenic fungus that is frequently isolated from water-damaged buildings or improperly stored feed. The secondary metabolites formed by this mold have been associated with health problems in humans and animals. Several authors have studied the influence of environmental conditions on the production of mycotoxins, but these studies focused on undefined or complex substrates, such as building materials and media that impeded investigations of the influence of specific nutrients. In this study, a chemically defined cultivation medium was used to investigate the impact of several nitrogen and carbon sources on growth of S. chartarum and its production of macrocyclic trichothecenes (MTs) and stachybotrylactam (STLAC). Increasing concentrations of sodium nitrate were found to positively affect mycelial growth, the level of sporulation, and MT production, while ammonium nitrate and ammonium chloride had an inhibitory effect. Potato starch was the superior and most reliable carbon source tested. Additionally, we observed that the level of sporulation was correlated with the production of MTs but not with that of STLAC. In this study, we provide a chemically well-defined cultivation medium suitable for standardized in vitro testing of the capacity of S. chartarum isolates to produce macrocyclic trichothecenes.}},
author = {{Tribelhorn, Katharina and Twarużek, Magdalena and Kosicki, Robert and Straubinger, Reinhard K. and Ebel, Frank and Ulrich, Sebastian}},
booktitle = {{Applied and Environmental Microbiology}},
issn = {{1098-5336}},
number = {{7}},
publisher = {{American Society for Microbiology}},
title = {{{A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam}}},
doi = {{10.1128/aem.00163-23}},
volume = {{89}},
year = {{2023}},
}
@misc{12942,
abstract = {{The ectoparasite Ixodes ricinus is an important vector for many tick-borne diseases (TBD) in the northern hemisphere, such as Lyme borreliosis, rickettsiosis, human granulocytic anaplasmosis, or tick-borne encephalitis virus. As climate change will lead to rising temperatures in the next years, we expect an increase in tick activity, tick population, and thus in the spread of TBD. Consequently, it has never been more critical to understand relationships within the microbial communities in ticks that might contribute to the tick’s fitness and the occurrence of TBD. Therefore, we analyzed the microbiota in different tick tissues such as midgut, salivary glands, and residual tick material, as well as the microbiota in complete Ixodes ricinus ticks using 16S rRNA gene amplicon sequencing. By using a newly developed DNA extraction protocol for tick tissue samples and a self-designed mock community, we were able to detect endosymbionts and pathogens that have been described in the literature previously. Further, this study displayed the usefulness of including a mock community during bioinformatic analysis to identify essential bacteria within the tick.}},
author = {{Wiesinger, Anna and Wenderlein, Jasmin and Ulrich, Sebastian and Hiereth, Stephanie and Chitimia-Dobler, Lidia and Straubinger, Reinhard K.}},
booktitle = {{International Journal of Molecular Sciences}},
issn = {{1422-0067}},
keywords = {{Ixodes ricinus, microbiome, tick-borne disease, salivary glands, midgut, endosymbiont, Candidatus Midichloria mitochondrii}},
number = {{2}},
publisher = {{MDPI AG}},
title = {{{Revealing the Tick Microbiome: Insights into Midgut and Salivary Gland Microbiota of Female Ixodes ricinus Ticks}}},
doi = {{10.3390/ijms24021100}},
volume = {{24}},
year = {{2023}},
}
@misc{12943,
abstract = {{Brown trout (Salmo trutta) is an important aquaculture species in Germany, but its production faces challenges due to global warming and a high embryo mortality. Climate factors might influence the fish’s bacterial community (BC) and thus increase embryo mortality. Yet, knowledge of the physiological BC during ontogeny in general is scarce. In this project, the BC of brown trout has been investigated in a period from unfertilized egg to 95 days post fertilization (dpf) using 16S rRNA gene amplicon sequencing. Developmental changes differed between early and late ontogeny and major differences in BC occurred especially during early developmental stages. Thus, analysis was conducted separately for 0 to 67 dpf and from 67 to 95 dpf. All analyzed stages were sampled in toto to avoid bias due to different sampling methods in different developmental stages. The most abundant phylum in the BC of all developmental stages was Pseudomonadota, while only two families (Comamonadaceae and Moraxellaceae) occurred in all developmental stages. The early developmental stages until 67 dpf displayed greater shifts in their BC regarding bacterial richness, microbial diversity, and taxonomic composition. Thereafter, in the fry stages, the BC seemed to stabilize and changes were moderate. In future studies, a reduction in the sampling time frames during early development, an increase in sampling numbers, and an attempt for biological reproduction in order to characterize the causes of these variations is recommended.}},
author = {{Keiz, Katharina and Ulrich, Sebastian and Wenderlein, Jasmin and Keferloher, Patrick and Wiesinger, Anna and Neuhaus, Klaus and Lagkouvardos, Ilias and Wedekind, Helmut and Straubinger, Reinhard K.}},
booktitle = {{Microorganisms : open access journal }},
issn = {{2076-2607}},
keywords = {{fish, brown trout, Salmo trutta, development, ontogeny, microbiome, bacterial community}},
number = {{1}},
publisher = {{MDPI AG}},
title = {{{The Development of the Bacterial Community of Brown Trout (Salmo trutta) during Ontogeny}}},
doi = {{10.3390/microorganisms11010211}},
volume = {{11}},
year = {{2023}},
}
@misc{13012,
abstract = {{The aim of the study is to provide an up-to date overall evaluation of visual contamination occurring on the slaughter line in order to provide a basis for implementing contamination control measures and to the hygienic quality of the processes. For this purpose, 627 contaminated pig carcasses in an industrial slaughterhouse in north western Germany were examined in 2021 for its distribution of type, areal extent and localization of slaughter contamination. Prior to official meat inspection, two persons visually scanned dorsal and ventral surfaces of the eviscerated but not yet split pig carcasses from cranial to caudal and recorded types, areal extent and localization of the contamination. The main contamination type were intestinal contents, bile, stomach contents, tubular rail fat and “others”, which mostly consisted of a reddish foam from the respiratory tract. 103 out of 627 contaminated animals showed more than one contamination, which leads to a total number of 754 contaminations detected. Intestinal contents accounted for almost half of all contaminations and “others” for 30%. Forelimb, back and ham together counted for 70% of the contaminated regions. The affected area was smaller than that of a one euro coin (diameter about 23 mm) in 86% of the cases.}},
author = {{Tholen, Janna and Grosse-Kleimann, J. and Schulze Althoff, G. and Kreienbrock, L. and Upmann, Matthias}},
booktitle = {{Meat Science}},
issn = {{1873-4138}},
keywords = {{Abattoir, Slaughter hygiene, Evisceration, Pork production, Pig carcass contamination, Fecal contamination, Bile contamination, Meat inspection}},
number = {{2}},
publisher = {{Elsevier BV}},
title = {{{Type, areal extent and localization of carcass contaminations during industrial pig slaughter}}},
doi = {{10.1016/j.meatsci.2023.109365}},
volume = {{208}},
year = {{2023}},
}
@article{7090,
abstract = {{The conventional method for the determination of the lethal heat load during pasteurisation (expressed in so-called pasteurisation units (PU)) by measuring temperature and flow rate provides known inaccuracies and requires safety margins in terms of a planned over-pasteurisation to the detriment of the product quality. Based on the hypothesis that chemical conversions correlate with applied heat input, despite the differences in reaction kinetics between chemical conversion and microbiological inactivation, inline near infrared spectroscopy (NIRS) was investigated to identify and quantify applied PU. Acid hydrolytic sucrose degradation was confirmed a favourable marker reaction. In a first step by still using offline analytics (HPLC) and a calculation the feasibility and plausibility in principle could be proved. Compared with conventional PU deviation of only 0.3% were found when using the chemical marker reaction. However, the inline application using NIRS showed too high variations. The too low accuracy of the NIRS model for the sucrose measurement was identified of being the cause for failing the overall goal. Improvements in the inline determination seem to be promising.}},
author = {{Weishaupt, Imke and Neubauer, Peter and Schneider, Jan}},
issn = {{1613-2041}},
journal = {{Brewing science}},
keywords = {{near infrared spectroscopy, apple juice, pasteurisation, acid hydrolytic sucrose degradation, inline measure-ment of heat input, pasteurisation units}},
number = {{1/2}},
pages = {{1--8}},
publisher = {{Carl}},
title = {{{Approach to an inline monitoring of the heat impact in a high temperature short time treatment (HTST) of juice with the help of a chemical marker}}},
doi = {{10.23763/BrSc21-20weishaupt}},
volume = {{75}},
year = {{2022}},
}
@misc{7444,
author = {{Wefing, Patrick and Conradi, Florian and Rämisch, Johannes and Neubauer, Peter and Schneider, Jan}},
booktitle = {{38th Congress of the European Brewery Convention (EBC 2022) : held 30 May - 1 June 2022, Madrid, Spain}},
isbn = {{978-1-7138-7038-8}},
location = {{Madrid}},
publisher = {{Curran Associates, Inc.}},
title = {{{Machine learning aided free amino nitrogen determination in beer mash with an inline NIR transflectance }}},
year = {{2022}},
}
@misc{7917,
author = {{Gossen, Arthur and Schwarzer, Knut and Weishaupt, Imke and Sürmeli, Baris Gün and Schneider, Jan}},
booktitle = {{Smarte Lösungen für eine nachhaltige Lebensmittelproduktion}},
location = {{Köln}},
title = {{{Flash Pasteurization with product and process monitoring using inline near infrared spectroscopy}}},
year = {{2022}},
}
@misc{7932,
author = {{Hernández Rodriguez, Tanja and Ramm, Selina and Lange-Hegermann, Markus and Frahm, Björn}},
location = {{Barcelona, Spain}},
title = {{{A systematic, model-based workflow for risk-based decision making in upstream development}}},
year = {{2022}},
}
@misc{7976,
author = {{Gassenmeier, Veronika and Deppe, Sahar and Hernández Rodriguez, Tanja and Kuhfuß, Fabian and Moser, André and Hass, Volker C. and Kuchemüller, Kim B. and Pörtner, Ralf and Möller, Johannes and Ifrim, George Adrian and Frahm, Björn}},
booktitle = {{Current Research in Biotechnology}},
issn = {{2590-2628 }},
pages = {{102--119}},
publisher = {{Elsevier}},
title = {{{Model-assisted DoE applied to microalgae processes, Current Research in Biotechnology}}},
doi = {{10.1016/j.crbiot.2022.01.005}},
volume = {{4}},
year = {{2022}},
}
@misc{7977,
abstract = {{Kinetic growth models are a useful tool for a better understanding of microalgal cultivation and for optimizing cultivation conditions. The evaluation of such models requires experimental data that is laborious to generate in bioreactor settings. The experimental shake flask setting used in this study allows to run 12 experiments at the same time, with 6 individual light intensities and light durations. This way, 54 biomass data sets were generated for the cultivation of the microalgae Chlorella vulgaris. To identify the model parameters, a stepwise parameter estimation procedure was applied. First, light-associated model parameters were estimated using additional measurements of local light intensities at differ heights within medium at different biomass concentrations. Next, substrate related model parameters were estimated, using experiments for which biomass and nitrate data were provided. Afterwards, growth-related model parameters were estimated by application of an extensive cross validation procedure.}},
author = {{Kuhfuß, Fabian and Gassenmeier, Veronika and Deppe, Sahar and Ifrim, George Adrian and Hernández Rodriguez, Tanja and Frahm, Björn}},
booktitle = {{Bioprocess and Biosystems Engineering}},
issn = {{1615-7605}},
pages = {{15--30}},
publisher = {{Springer}},
title = {{{View on a mechanistic model of Chlorella vulgaris in incubated shake flasks}}},
doi = {{10.1007/s00449-021-02627-2}},
volume = {{45}},
year = {{2022}},
}
@misc{11377,
abstract = {{consuming and often performed rather empirically. Efficient optimization of multiple objectives such as process time, viable cell density, number of operating steps & cultivation scales, required medium, amount of product as well as product quality depicts a promising approach. This contribution presents a workflow which couples uncertainty-based upstream simulation and Bayes optimization using Gaussian processes. Its application is demonstrated in a simulation case study for a relevant industrial task in process development, the design of a robust cell culture expansion process (seed train), meaning that despite uncertainties and variabilities concerning cell growth, low variations of viable cell density during the seed train are obtained. Compared to a non-optimized reference seed train, the optimized process showed much lower deviation rates regarding viable cell densities (<10% instead of 41.7%) using five or four shake flask scales and seed train duration could be reduced by 56 h from 576 h to 520 h. Overall, it is shown that applying Bayes optimization allows for optimization of a multi-objective optimization function with several optimizable input variables and under a considerable amount of constraints with a low computational effort. This approach provides the potential to be used in the form of a decision tool, e.g., for the choice of an optimal and robust seed train design or for further optimization tasks within process development.}},
author = {{Hernández Rodriguez, Tanja and Sekulic, Anton and Lange-Hegermann, Markus and Frahm, Björn}},
booktitle = {{Processes}},
issn = {{2227-9717}},
keywords = {{Gaussian processes, Bayes optimization, Pareto optimization, multi-objective, cell culture, seed train}},
number = {{5}},
publisher = {{MDPI AG}},
title = {{{Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design}}},
doi = {{10.3390/pr10050883}},
volume = {{10}},
year = {{2022}},
}
@misc{11545,
author = {{Katsch, Linda and Trilling-Haasler, Marc and Schneider, Jan}},
location = {{Lemgo}},
title = {{{Recyclate Transparency}}},
year = {{2022}},
}
@misc{12006,
author = {{Jäger, Alina and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Frankfurt am Main}},
title = {{{Vergleich der Behandlungen von trockenem und erntefrischem Oregano mittels Mechanischer Sattdampfentkeimung}}},
year = {{2022}},
}
@misc{8424,
author = {{Katsch, Linda and Conradi, Florian and Wefing, Patrick and Schneider, Jan}},
booktitle = {{38th Congress of the European Brewery Convention (EBC 2022) : held 30 May - 1 June 2022, Madrid, Spain }},
isbn = {{978-1-7138-7038-8 }},
location = {{Madrid}},
publisher = {{Curran Associates, Inc.}},
title = {{{Determination and prediction of the final attenuation and quality parameters in beer with near-infrared spectroscopy}}},
year = {{2022}},
}
@misc{8425,
author = {{Katsch, Linda and Schneider, Jan}},
booktitle = {{Brauwelt international : special journal covering the brewing and beverage industries}},
issn = {{0934-9340}},
number = {{3}},
pages = {{182--185}},
publisher = {{Fachverlag Hans Carl GmbH}},
title = {{{Potential for gentler pasteurization}}},
year = {{2022}},
}
@misc{8429,
author = {{Pauli, Daniel and Neumaier, Michael}},
location = {{Köln}},
publisher = {{DLG}},
title = {{{On the way to intelligent shelf life prediction}}},
year = {{2022}},
}
@misc{8443,
author = {{Upmann, Matthias and Tholen, Janna and Schulze Althoff, Gereon}},
location = {{Leipzig}},
title = {{{Salmonellen - Risikominimierung in der Schlachtstrecke durch visuelle Kontrollsysteme und künstliche Intelligenz}}},
year = {{2022}},
}
@misc{8446,
author = {{Gossen, Arthur and Schwarzer, Knut and Sürmeli, Baris Gün and Weishaupt, Imke and Schneider, Jan}},
location = {{Madrid}},
title = {{{Smart Pasteurization Pilot Plant - a new approach with inline sensors towards a precise and gentle flash pasteurization}}},
year = {{2022}},
}
@misc{8447,
author = {{Schwarzer, Knut and Müller, Ulrich and Schneider, Jan}},
keywords = {{Pasteurization, minimal processing}},
location = {{Madrid}},
title = {{{Rethink Beer Pasteurization – Safety, Sustainability and Quality}}},
year = {{2022}},
}
@misc{8450,
author = {{Schwarzer, Knut and Weishaupt, Imke and Gossen, Arthur and Sürmeli, Baris Gün and Schneider, Jan}},
location = {{Frankfurt}},
title = {{{Smart Pasteurization - Eine neuartige, autonome Regelung für eine Kurzzeiterhitzung}}},
year = {{2022}},
}
@misc{9196,
author = {{Trilling, Marc and Katsch, Linda and Schneider, Jan}},
location = {{Bregenz}},
title = {{{Recyclat Transparency}}},
year = {{2022}},
}
@misc{9197,
author = {{Wittland, Sebastian and Sokolowsky, Martina and Kanzler, Clemens and Rohn, Sascha and Bertrand, Matthäus and Sciurba, Elisabeth}},
booktitle = {{Lebensmittelchemie : Zeitschrift der Lebensmittelchemischen Gesellschaft, Fachgruppe in der Gesellschaft Deutscher Chemiker }},
issn = {{1521-3811}},
location = {{Hamburg}},
number = {{S2}},
pages = {{229}},
publisher = {{Wiley-VCH }},
title = {{{Allulose in Backwaren - Charakterisierung des Einflusses von Allulose in Kombination mit verschiedenen Getreidearten und Mehltypen auf die Produktqualität von Feinen Backwaren}}},
doi = {{ https://doi.org/10.1002/lemi.202259182 }},
volume = {{76}},
year = {{2022}},
}
@misc{9416,
author = {{Upmann, Matthias and Weyland, Gerd}},
booktitle = {{Fleischwirtschaft}},
issn = {{0015-363X }},
location = {{Lemgo}},
number = {{11}},
pages = {{42--46}},
publisher = {{dfv-Mediengruppe, Dt. Fachverl. }},
title = {{{Was ist erlaubt, was verboten?}}},
volume = {{101}},
year = {{2022}},
}
@misc{9417,
author = {{Upmann, Matthias and Weyland, Gerd}},
booktitle = {{Fleischwirtschaft}},
issn = {{0015-363X}},
location = {{Lemgo}},
number = {{12}},
pages = {{50--55}},
publisher = {{dfv-Mediengruppe, Dt. Fachverl.}},
title = {{{Was ist erlaubt, was verboten?}}},
volume = {{101}},
year = {{2022}},
}
@misc{9419,
author = {{Upmann, Matthias and Stiebing, Achim}},
location = {{Lemgo}},
title = {{{In eigener Sache: Studium der Fleischtechnologie gestern - heute - morgen }}},
year = {{2022}},
}
@misc{9420,
abstract = {{Larger processing equipment to produce minced meat could affect its structure due to intensive processing and a high energy intake in the meat mass. To assess if this would result in alterations in the minced meat quality, finely chopped meat (FCM) was added in different concentrations (15, 30, 45, 60, 75, 90, and 100%) to minced meat and quality parameters were analyzed. FCM was used to simulate different intensity of an unintended destruction of meat cells due to various processes. The amount of non-intact cells (ANIC) was determined histologically and furthermore, soluble protein content, water holding capacity, mechanical and sensory texture, and scanning electron and confocal laser scanning microscopy was applied to analyze the meat structure and quality. ANIC indicated that even adding 15% FCM was statistically (p < 0.05) distinguishable from 100% minced meat and 30% FCM had already 50 Vol.-% ANIC. In contrast, the addition of 15% or 30% FCM did not result in significant differences in drip loss of raw and cooked meat as well as mechanical and sensory texture analysis. This study showed that intensive processing might be detectable via ANIC, but that the minced meat quality was not affected.}},
author = {{Witte , Franziska and Sawas , Erik and Berger , Lisa M. and Gibis , Monika and Weiss, Jochen and Röser, Anja and Upmann, Matthias and Joeres, Eike and Juadjur , Andreas and Bindrich , Ute and Heinz , Volker and Terjung, Nino}},
booktitle = {{Applied Sciences}},
issn = {{2076-3417 }},
keywords = {{minced pork, industrial meat processing, quality characterization, techno-functional properties of minced pork, structural modification}},
number = {{12}},
publisher = {{MDPI}},
title = {{{Influence of Finely Chopped Meat Addition on Quality Parameters of Minced Meat}}},
doi = {{https://doi.org/10.3390/app122010590}},
volume = {{20}},
year = {{2022}},
}
@misc{9421,
author = {{Tholen, Janna and Mohr, Jessica and Bruns, Michael and Schulze Althoff, Gereon and Upmann, Matthias}},
location = {{Garmisch-Partenkirchen}},
title = {{{Kontaminationen während des Schlachtprozesses auf Schweineschlachtkörpern}}},
year = {{2022}},
}
@misc{9568,
abstract = {{Pellet production is a multi-step manufacturing process comprising granulation, extrusion and spheronisation. The first step represents a critical control point, since the quality of the granule mass highly influences subsequent process steps and, consequently, the quality of final pellets. The most important parameter of wet granulation is the liquid requirement, which can often only be quantitatively evaluated after further process steps. To identify an alternative for optimal liquid requirements, experiments were conducted with a formulation based on lactose and microcrystalline cellulose. Granules were analyzed with a Powder Vertical Shear Rig. We identified the compression density (ρpress) as the said alternative, linking information from the powder material and the moisture content (R2 = 0.995). We used ρpress to successfully predict liquid requirements for unknown formulation compositions. By means of this prediction, pellets with high quality, regarding shape and size distribution, were produced by carrying out a multi-step manufacturing process. Furthermore, the applicability of ρpress as an alternative quality parameter to other placebo formulations and to formulations containing active pharmaceutical ingredients (APIs) was demonstrated.}},
author = {{Ramm, Selina and Fulek, Ruwen and Eberle, Veronika Anna and Kiera, Christian and Odefey, Ulrich and Pein-Hackelbusch, Miriam}},
booktitle = {{Pharmaceutics}},
issn = {{1999-4923}},
keywords = {{wet granulation, liquid requirement, granulation endpoint, compression density}},
number = {{11}},
publisher = {{MDPI}},
title = {{{Compression Density as an Alternative to Identify an Optimal Moisture Content for High Shear Wet Granulation as an Initial Step for Spheronisation.}}},
doi = {{https://doi.org/10.3390/pharmaceutics14112303}},
volume = {{14}},
year = {{2022}},
}
@misc{10190,
author = {{Gassenmeier, Veronika and Frahm, Björn}},
publisher = {{assets-labs}},
title = {{{Real-time Monitoring of DCO2 in addition to DO}}},
year = {{2022}},
}
@inbook{10193,
abstract = {{Development and optimization of biopharmaceutical production processes with cell cultures is cost- and time-consuming and often performed rather empirically. Efficient optimization of multiple objectives such as process time, viable cell density, number of operating steps & cultivation scales, required medium, amount of product as well as product quality depicts a promising approach. This contribution presents a workflow which couples uncertainty-based upstream simulation and Bayes optimization using Gaussian processes. Its application is demonstrated in a simulation case study for a relevant industrial task in process development, the design of a robust cell culture expansion process (seed train), meaning that despite uncertainties and variabilities concerning cell growth, low variations of viable cell density during the seed train are obtained. Compared to a non-optimized reference seed train, the optimized process showed much lower deviation rates regarding viable cell densities (<10% instead of 41.7%) using five or four shake flask scales and seed train duration could be reduced by 56 h from 576 h to 520 h. Overall, it is shown that applying Bayes optimization allows for optimization of a multi-objective optimization function with several optimizable input variables and under a considerable amount of constraints with a low computational effort. This approach provides the potential to be used in the form of a decision tool, e.g., for the choice of an optimal and robust seed train design or for further optimization tasks within process development.}},
author = {{Hernández Rodriguez, Tanja and Sekulic, Anton and Lange-Hegermann, Markus and Frahm, Björn}},
booktitle = {{Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing}},
editor = {{Pörtner, Ralf and Möller, Johannes}},
isbn = {{978-3-0365-5210-1}},
issn = {{2227-9717}},
keywords = {{Gaussian processes, Bayes optimization, Pareto optimization, multi-objective, cell culture, seed train}},
pages = {{21--48}},
publisher = {{MDPI}},
title = {{{Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design}}},
doi = {{https://doi.org/10.3390/pr10050883}},
volume = {{special issue}},
year = {{2022}},
}
@misc{10195,
author = {{Blome, André and Luttmann, Mario and Segermann, Jan and Jekle, Mario and Frahm, Björn and Müller, Ulrich}},
booktitle = {{Proceedings of the 33rd VH Yeast Conference 2022: Advances in Applied Research & Industrial Production of Baker’s Yeast, “100th anniversary of VH Berlin & Yeast(s) as an alternative protein source”}},
location = {{Berlin, Germany}},
pages = {{61 -- 66}},
publisher = {{Versuchsanstalt der Hefeindustrie e.V.}},
title = {{{Process optimisation in the field of wheat dough processing using real-time recording of quality-relevant characteristics in raw materials, intermediates and final products}}},
year = {{2022}},
}
@misc{10196,
author = {{Blome, André and Luttmann, Mario and Segermann, Jan and Jekle, Mario and Frahm, Björn and Müller, Ulrich}},
location = {{Berlin, Germany}},
title = {{{Process optimisation in the field of wheat dough processing using real-time recording of quality-relevant characteristics in raw materials, intermediates and final products}}},
year = {{2022}},
}
@misc{10197,
author = {{Hernández Rodriguez, Tanja and Posch, Christoph and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{ACHEMA 2022}},
location = {{Frankfurt am Main, Germany}},
title = {{{Model assisted Design Strategies for Bioprocesses – Advanced statistical methods in industrial upstream cell culture}}},
year = {{2022}},
}
@misc{10198,
author = {{Hernández Rodriguez, Tanja and Pörtner, Ralf and Lange-Hegermann, Markus and Wurm, Florian M. and Frahm, Björn}},
location = {{Lisbon, Portugal }},
title = {{{A systematic, model-based approach for decision making in upstream development – Considerations regarding clone selection and cell expansion}}},
year = {{2022}},
}
@misc{10199,
author = {{Müller, Carolin and Alarinta, Jarmo and Frahm, Björn and Wirtanen, Gun}},
booktitle = {{PBN 2022 Congress}},
location = {{Zagreb, Croatia}},
title = {{{Microbial spoilage in vegan foods}}},
year = {{2022}},
}
@article{5425,
abstract = {{The feasibility of inline classification and characterization of seven fruit juice varieties was investigated by the application of near-infrared spectroscopy (NIRS) combined with chemometrics. The findings are intended to be used to optimize the flash pasteurization of liquid foods. More precise information of the kind of product in real time had to be achieved to enable a more product-specific process. Using the method of partial least squares discriminant analysis, the fruit juice varieties were classified, showing a classification rate of 100% regarding an internal and 69% regarding an external test sets. A characterization by the extract content, pH value, turbidity, and viscosity was made by fitting a partial least squares regression model. The percentage prediction error of the pH value was <3% for internal and external test sets, and for the Brix value prediction errors were about 4% (internal) and 20% (external). The parameters viscosity and turbidity were found to be unsuitable. Despite this, the strategy applied to gain more product-specific information in real time showed to be feasible. By linking the results to a database containing potentially harmful microorganisms for various types of fruit juices, a more product-specific calculation of the necessary heat input can be performed. To demonstrate the practical relevance, a comparison between conventional and product-adapted process control was performed using two fruit varieties as examples in case of Alicyclobacillus acidoterrestris. Thus, with more accurate product information, achieved through the use of NIRS with chemometrics, a more precise calculation of the heat input can be achieved.}},
author = {{Weishaupt, Imke and Neubauer, Peter and Schneider, Jan}},
issn = {{2048-7177}},
journal = {{Food Science & Nutrition}},
keywords = {{flash pasteurization, fruit juice characterization and classification, inline near-infrared spectroscopy, multivariate data analysis}},
number = {{3}},
pages = {{800--812}},
publisher = {{Wiley}},
title = {{{Near-infrared spectroscopy for the inline classification and characterization of fruit juices for a product-customized flash pasteurization}}},
doi = {{ https://doi.org/10.1002/fsn3.2709}},
volume = {{10}},
year = {{2022}},
}
@misc{12833,
abstract = {{In Northwestern Europe, Germany, France, the Netherlands, the UK and Belgium constitute the biggest five potato producers, with total potato crop production around 60% of EU-28 production before Brexit. Soil and climate conditions are highly favourable for potato growth in this region. Production is under driving forces of (i) the potato processing industry, particularly in Belgium; (ii) the innovation for fresh potato in the UK, France and Germany; (iii) the leadership of Germany and the Netherlands for starch potato; and (iv) the dominance of the Netherlands for seed production. Based on an industrial agri-food production system, the region has the highest potato yield levels worldwide and developed relevant trade networks for export of seed, fresh and processed potato products in and outside Europe. Conventional and intensive potato production is widespread over the region, whilst organic production started to develop in Germany and France. Whether the coming decades will be as successful as the last ones for sustainable potato production will depend on how the sector and stakeholders of the whole potato value-chain will overcome new issues and challenges. These are mainly soil quality and health conservation, consequences of climate change, increasing bans on the use of plant protection products, tightening environmental standards, food waste reduction and increasing trade tensions hampering the flow of potatoes around the world. After a detailed description of the potato production in the region, this paper contains a SWOT analysis aiming to identify potential solutions to overcome environmental, technical, economic, political and societal issues in the region for sustainable potato production in the coming years and decades.}},
author = {{Goffart, Jean-Pierre and Haverkort, Anton and Storey, Michael and Haase, Norbert and Martin, Michel and Lebrun, Pierre and Ryckmans, Daniel and Florins, Dominique and Demeulemeester, Kürt}},
booktitle = {{ Potato research : journal of the European Association for Potato Research}},
issn = {{1871-4528}},
keywords = {{Industrial agri-food production, Production practices, Sustainability, Value-chain}},
number = {{3}},
pages = {{503--547}},
publisher = {{Springer }},
title = {{{Potato Production in Northwestern Europe (Germany, France, the Netherlands, United Kingdom, Belgium): Characteristics, Issues, Challenges and Opportunities}}},
doi = {{10.1007/s11540-021-09535-8}},
volume = {{65}},
year = {{2022}},
}
@misc{12944,
abstract = {{Lyme borreliosis is a vector-borne disease in humans and animals caused by bacteria from the Borrelia burgdorferi sensu lato complex (Bbsl). The possible transmission of Bbsl from companion animals to humans via ticks makes this disease important in terms of One Health approaches. Thus, early and accurate diagnosis and treatment are of utmost importance. Today’s standard for the detection of specific antibodies against Bbsl is a two-tiered test system based on an ELISA for screening combined with a line immunoassay (LIA) for confirmation. In this study, 200 canine and 200 equine serum samples with known antibody status were tested with two different LIAs (A and B). Results were compared regarding sensitivity, specificity, the diagnostic outcome for dogs and horses, as well as operability of the test. The results for canine serum samples corresponded to 94.0%, making both LIAs a good choice for LB diagnostic in dogs. For equine serum samples, the agreement of both tests was 65.5%, displaying the challenge equine samples still provide in LB diagnostic. Major concerns were the interpretation of the OspA antigen (AG) signal and the use of unspecific (i.e., p100/p83) or too sensitive signals on the LIA. The operability of both LIAs was equally user-friendly. Regarding the tests’ evaluation, the scanning process provided by LIA A was a major advantage considering the comparability of the tests.}},
author = {{Doff, Sophie and Wenderlein, Jasmin and Wiesinger, Anna and Hiereth, Stephanie and Ulrich, Sebastian and Straubinger, Reinhard}},
booktitle = {{Veterinary Sciences : open access journal}},
issn = {{2306-7381}},
keywords = {{antibody, Borrelia burgdorferi sensu lato, canine, equine, serum diagnosis, line immunoassay}},
number = {{11}},
publisher = {{MDPI}},
title = {{{Detection of Borrelia burgdorferi sensu-lato-Specific Antibodies in Sera of Canine and Equine Origin—A Comparative Study with Two Line Immunoassays}}},
doi = {{10.3390/vetsci9110633}},
volume = {{9}},
year = {{2022}},
}
@misc{12945,
abstract = {{Stachybotrys chartarum is a toxigenic fungus that is frequently isolated from damp building materials or improperly stored forage. Macrocyclic trichothecenes and in particular satratoxins are the most potent mycotoxins known to be produced by this fungus. Exposure of humans or animals to these secondary metabolites can be associated with severe health problems. To assess the pathogenic potential of S. chartarum isolates, it is essential to cultivate them under conditions that reliably promote toxin production. Potato dextrose agar (PDA) was reported to be the optimal nutrition medium for satratoxin production. In this study, the growth of S. chartarum genotype S strains on PDA from two manufacturers led to divergent results, namely, well-grown and sporulating cultures with high satratoxin concentrations (20.8 ± 0.4 µg/cm2) versus cultures with sparse sporulation and low satratoxin production (0.3 ± 0.1 µg/cm2). This finding is important for any attempt to identify toxigenic S. chartarum isolates. Further experiments performed with the two media provided strong evidence for a link between satratoxin production and sporulation. A comparison of three-point and one-point cultures grown on the two types of PDA, furthermore, demonstrated an inter-colony communication that influences both sporulation and mycotoxin production of S. chartarum genotype S strains.}},
author = {{Tribelhorn, Katharina and Twarużek, Magdalena and Soszczyńska, Ewelina and Rau, Jörg and Baschien, Christiane and Straubinger, Reinhard K. and Ebel, Frank and Ulrich, Sebastian}},
booktitle = {{Toxins}},
issn = {{2072-6651}},
keywords = {{Stachybotrys chartarum genotype S, sporulation, satratoxins, macrocyclic trichothecenes, inter-colony communication}},
number = {{8}},
publisher = {{MDPI}},
title = {{{Production of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys chartarum}}},
doi = {{10.3390/toxins14080515}},
volume = {{14}},
year = {{2022}},
}
@misc{12946,
abstract = {{Ostrich meat is characterized by high nutritional value; however, it remains an exotic product in most countries worldwide. In Europe, only few data are available regarding its microbial contamination, prevalence of antimicrobial-resistant bacteria, and safety. Therefore, this study aimed to investigate the microbiological quality and safety of ostrich meat samples (n = 55), each from one animal, produced in Bavaria, Germany. The provided microbiological status of ostrich meat included mesophilic aerobic bacteria, Enterobacteria, and mesophilic yeast and molds. In terms of food safety, all meat samples were negative for Salmonella spp. and Trichinella spp. Additionally, meat samples and a further 30 stool samples from 30 individuals were investigated for Shiga toxin-producing Escherichia coli genes, with two meat samples that were qPCR-positive. Antimicrobial-resistant Enterobacteriaceae, Enterococcus faecalis, and Enterococcus faecium strains were from meat and stool samples also analyzed; 13 potentially resistant Enterobacteriaceae (meat samples) and 4 Enterococcus faecium (stool samples) were isolated, and their susceptibility against 29 and 14 antimicrobials, respectively, was characterized. The results of this study provide an overview of microbial loads and food safety aspects that may be used as baseline data for the ostrich meat industry to improve their hygienic quality. However, the implementation of monitoring programs is recommended, and microbiological standards for ostrich meat production should be established.}},
author = {{Beindorf, Philipp-Michael and Kovalenko, Oksana and Ulrich, Sebastian and Geißler, Hanna and Korbel, Rüdiger and Schwaiger, Karin and Dorn-In, Samart and Esteban-Cuesta, Irene}},
booktitle = {{Biology : open access journal}},
issn = {{2079-7737}},
keywords = {{antimicrobial resistance, meat microbiology, Salmonella, STEC, Trichinella}},
number = {{7}},
publisher = {{MDPI}},
title = {{{Investigation of Meat from Ostriches Raised and Slaughtered in Bavaria, Germany: Microbiological Quality and Antimicrobial Resistance}}},
doi = {{10.3390/biology11070985}},
volume = {{11}},
year = {{2022}},
}
@misc{12947,
abstract = {{Stachybotrys chartarum is frequently isolated from damp building materials or improperly stored animal forage. Human and animal exposure to the secondary metabolites of this mold is linked to severe health effects. The mutually exclusive production of either satratoxins or atranones defines the chemotypes A and S. Based upon the genes (satratoxin cluster, SC1-3, sat or atranone cluster, AC1, atr) that are supposed to be essential for satratoxin and atranone production, S. chartarum can furthermore be divided into three genotypes: the S-type possessing all sat- but no atr-genes, the A-type lacking the sat- but harboring all atr-genes, and the H-type having only certain sat- and all atr-genes. We analyzed the above-mentioned gene clusters and their flanking regions to shed light on the evolutionary relationship. Furthermore, we performed a deep re-sequencing and LC-MS/MS (Liquid chromatography–mass spectrometry) analysis. We propose a first model for the evolution of the S. chartarum genotypes. We assume that genotype H represents the most ancient form. A loss of the AC1 and the concomitant acquisition of the SC2 led to the emergence of the genotype S. According to our model, the genotype H also developed towards genotype A, a process that was accompanied by a loss of SC1 and SC3.}},
author = {{Ulrich, Sebastian and Lang, Katharina and Niessen, Ludwig and Baschien, Christiane and Kosicki, Robert and Twarużek, Magdalena and Straubinger, Reinhard K. and Ebel, Frank}},
booktitle = {{Journal of Fungi}},
issn = {{2309-608X}},
keywords = {{Stachybotrys, genome, macrocyclic trichothecene, atranone}},
number = {{4}},
publisher = {{MDPI AG}},
title = {{{The Evolution of the Satratoxin and Atranone Gene Clusters of Stachybotrys chartarum}}},
doi = {{10.3390/jof8040340}},
volume = {{8}},
year = {{2022}},
}
@misc{12948,
abstract = {{Diet processing impacts on starch properties, such as the degree of starch gelatinization. This affects digestibility, as shown in laboratory mice fed either a pelleted or an extruded diet. In the present study, the morphology of starch particles throughout the digestive tract of mice was visualized. Thirty-two female C57BL/6J mice were used for a feeding trial. They were fed a commercial maintenance diet for laboratory mice, which was available in pelleted and extruded form, for seven weeks. The mice were sacrificed after the feeding period, and chyme samples were collected from five sites (stomach, anterior and posterior small intestine, caecum, colon). Samples of diets, chyme and faeces were analyzed via stereomicroscopy (stained with Lugol’s iodine) and scanning electron microscopy (SEM). The starch granules appeared more compact in the pelleted diet, showing first signs of degradation only in the small intestine. The caecum content of both diets group was intensively stained, particles as well as fluid phase, indicating that it contained mainly starch. The SEM pictures of caecum content showed abundant bacteria near starch particles. This suggests selective retention of prae-caecally undigested starch in the murine caecum, likely the site of microbial fermentation.}},
author = {{Wenderlein, Jasmin and Kienzle, Ellen and Straubinger, Reinhard K. and Schöl, Heidrun and Ulrich, Sebastian and Böswald, Linda Franziska}},
booktitle = {{Animals}},
issn = {{2076-2615}},
keywords = {{amylase, carbohydrate metabolism, processing, laboratory animal diets, caecum fermentation}},
number = {{8}},
publisher = {{MDPI AG}},
title = {{{Morphology of Starch Particles along the Passage through the Gastrointestinal Tract in Laboratory Mice Fed Extruded and Pelleted Diets}}},
doi = {{10.3390/ani12080952}},
volume = {{12}},
year = {{2022}},
}
@misc{12957,
abstract = {{Mit dieser Arbeit sollte die klinische Relevanz von Infektionen mit Borrelia burgdorferi sensu lato (Bbsl) sowie Anaplas-
ma phagocytophilum (Ap) bei Pferden in Deutschland untersucht und mögliche Assoziationen zwischen typischen klinischen Veränderungen und spezifischen erhöhten Serumantikörperspiegeln gefunden werden. Hierfür wurden Pferde mit dem Verdacht auf eine klinisch manifeste Lyme-Borreliose (LB) deutschlandweit untersucht. Die Tierärzte wurden zudem gebeten, einen Befund- bzw. Fragebogen auszufüllen. Neben einer Blutprobe von dem LB-erkrankten bzw. -verdächtigen Pferd wurde immer auch eine Blutprobe eines gesunden Kontrollpferdes aus dem gleichen Bestand entnommen. Die Blutproben wurden mittels ELISA (enzyme-linked immunosorbent assay) und Line-Immunoassay auf spezifische Antikörper (Ak) gegen Bbsl und zusätzlich mittels eines validierten SNAP-Tests (SNAP® 4Dx Plus® ELISA) auf spezifische Ak für Bbsl und Anaplasma phagocytophilum (Ap) untersucht. Zudem wurde ein manueller Ausstrich auf Einschlusskörperchen in den Granulozyten, die auf eine Ap-Infektion hindeuten, untersucht. Insgesamt wurden 123 LB-Verdachts- und 113 Kontrollpferde an der Studie aufgenommen. 114 Tierarztfragebögen und Blutproben lagen vollständig vor und gingen in die statistische Auswertung ein. Die häufigsten Vorstellungsgründe der LB-Verdachtstiere waren Lahmheit (n = 36; nges = 79; 45,6 %), Leistungsschwäche (n = 19; 24,1 %) und Apathie (n = 12; 15,2 %). Bei fast der Hälfte der Patienten wurden die klinischen Veränderungen bereits seit über sechs Monaten beobachtet (n = 48; nges = 112; 42,9 %). Zahlreiche Tiere zeigten mehrere, oftmals unspezifische klinische Veränderungen (n = 104; nges = 114; 92,2 %) und/oder litten zusätzlich unter einer chronischen Erkrankung (n = 48; nges = 114; 42,5 %). Obwohl in vielen Fällen schon eine weiterführende Infektionsdiagnostik (n = 64 von nges = 114; 56,1 %) durchgeführt worden war, wurden einige Pferde bislang noch nicht weitergehend labordiagnostisch untersucht (n = 14; nges = 114; 12,3 %). Bei 15 % der Probanden (n = 29; nges = 112) war zudem bislang noch keine eingehende Untersuchung einzelner Organsysteme erfolgt. Auf Basis der eigenen serologischen Befunde wurden 51 % (n = 63) der LB Verdachtspferde negativ (49 % der Verdachtspferde; n = 55), 28 % (n = 34) wurden grenzwertig (35 % der Kontrollpferde; n = 40) und 21 % (n = 26) positiv (16 % der Kontrollpferde; n = 18) auf spezifische Ak gegen Bbsl getestet. Ein positiver Ap-spezifischer Ak-Nachweis lag bei 19,5 % der Verdachtspferde (16,8 % der Kontrollpferde) vor. Ein Hinweis auf eine Coinfektion mit Bbsl und Ap konnte bei sieben Verdachtstieren (5,7 %; 2 Kontrollpferde, 1.8 %) gefunden werden. Die Blutausstriche waren bei allen Verdachts- und Kontrolltieren, bei denen sie auswertbar waren (n = 98), ohne besonderen Befund. Die hohe Zahl klinisch inapparenter Verläufe von Infektionen mit Bbsl konnte durch die hohe Zahl seropositiver Probanden (n = 18; nges = 112; 16 %)
in der gesunden Kontrollgruppe (KG) bestätigt werden. Insgesamt ergab sich ein kaum differierender Serostatus von Verdachts- und Kontrollpferden (p = 0,887). Es konnten mit dem gewonnenen Datenmaterial keine pathognomonisch definierten, klinischen Veränderungen für die LB bei Pferden herausgearbeitet werden. Weder das gehäufte Auftreten unspezifischer Störungen des Allgemeinbefindens (p = 0,043), noch Lahmheiten (p = 0,782) oder Gelenkschwellungen (p = 0,013) konnten statistisch signifikant im Zusammenhang mit positivem Bbsl-Ak-Nachweis beobachtet werden. Die Chance für einen positiven Ap-Ak-Nachweis war bei Fieber (OR = 3,54 (1,28–9,73)) und Inappetenz (OR = 4,54 (1,44–14,29)) erhöht. Bei Coinfektionen (Bbsl + Ap) wurden zudem auffallend häufig neurologische Veränderungen, wie Kopfnervenausfälle (p = 0,030) und Hinweise auf eine Meningoenzephalitis (p = 0,003) diagnostiziert, wobei letztere Korrelation aufgrund der geringen Anzahl
an betroffenen Patienten mit einer Unsicherheit hinsichtlich der Praxisrelevanz behaftet ist.}},
author = {{Gehlen, Heidrun and Inerle, Katharina S and Ulrich, Sebastian and Briese, Beatrice and Straubinger, Reinhard K.}},
booktitle = {{Pferdeheilkunde }},
issn = {{2943-1794 }},
keywords = {{Equine Lyme-Borreliose, Equine Granulozytäre Anaplasmose, Seroprävalenz, Coinfektion}},
number = {{6}},
pages = {{544–553}},
publisher = {{Hippiatrika-Verl. GmbH }},
title = {{{Lyme-Borreliose und Granulozytäre Anaplasmose bei Pferden Teil 2 – Klinische Relevanz (Tierarztbefragung)}}},
doi = {{10.21836/PEM20220606}},
volume = {{38}},
year = {{2022}},
}
@inproceedings{6569,
author = {{Upmann, Matthias}},
location = {{Lemgo}},
publisher = {{Technische Hochschule Ostwestfalen Lippe}},
title = {{{Zart oder hart? Neue Forschungsansätze zur Zartheitsprognose von Rindfleisch}}},
year = {{2021}},
}
@article{6573,
author = {{Upmann, Matthias and Krämer, Karl-Heinz and Benkhoff , Franz-Josef and Lautenschläger, Ralf}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{7}},
pages = {{28--61}},
publisher = {{Deutscher Fachverlag}},
title = {{{Was kommt, was bleibt, was geht? Teil 1 und 2}}},
volume = {{100}},
year = {{2021}},
}
@article{6574,
author = {{Upmann, Matthias and Weyland, Gerd}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{52--54}},
publisher = {{Dt. Fachverl.}},
title = {{{Was ist erlaubt, was verboten? 16. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost – 1. Teil}}},
volume = {{100}},
year = {{2021}},
}
@article{6575,
author = {{Upmann, Matthias and Weyland, Gerd}},
issn = {{0015-363x }},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{42--44}},
publisher = {{Dt. Fachverl. }},
title = {{{Was ist erlaubt, was verboten? 16. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost – 2. Teil}}},
volume = {{100}},
year = {{2021}},
}
@inproceedings{6576,
author = {{Upmann, Matthias and Röser, Anja and Jostmeyer, Friedrich-Christian}},
booktitle = {{61. Arbeitstagung des Arbeitsgebietes Lebensmittelsicherheit und Verbraucherschutz}},
location = {{Garmisch-Partenkirchen}},
publisher = {{Eigenverlag}},
title = {{{Einflussfaktoren auf das Ergebnis des HADH-Gefrierfleischnachweises}}},
year = {{2021}},
}
@misc{6577,
author = {{Fechner, Tim and Röser, Anja and Upmann, Matthias}},
booktitle = {{61. Arbeitstagung des Arbeitsgebietes Lebensmittelsicherheit und Verbraucherschutz}},
isbn = {{978-3-86345-584-2}},
location = {{Garmisch-Partenkirchen}},
publisher = {{Verlag der DVG Service GmbH }},
title = {{{Knochenpartikel in Geflügel-Verarbeitungsfleisch – Rohstoffbedingte Schwankungen innerhalb einer Arbeitswoche}}},
year = {{2021}},
}
@inproceedings{6732,
author = {{Conradi, Florian}},
location = {{Leuven, Belgien}},
title = {{{Real time quality controlled mashing – a successful approach using inline near infrared spectroscopy and advanced data analysis}}},
year = {{2021}},
}
@inproceedings{6734,
author = {{Pauli, Daniel and Neumaier, Michael}},
location = {{Magdeburg}},
title = {{{Einsatz von technischer Sensorik im Projekt DproFood }}},
year = {{2021}},
}
@inproceedings{6825,
author = {{Conradi, Florian}},
location = {{Hard}},
title = {{{Rezyklaterkennung in PET-Preforms}}},
year = {{2021}},
}
@inproceedings{6840,
author = {{Pauli, Daniel and Wisser, Stephanie}},
location = {{Online}},
title = {{{Datenanalyse und autonome Prognostik zur Verbesserung der Transparenz und Sicherheit von Lebensmitteln}}},
year = {{2021}},
}
@inproceedings{6842,
author = {{Pauli, Daniel and Neumaier, Michael and Scharf, Matthias and Funke, Carsten}},
location = {{Online}},
title = {{{Von der offline zur online Qualitätskontrolle mittels Echtzeit- und Fingerprint-Analytik}}},
year = {{2021}},
}
@article{6926,
author = {{Upmann, Matthias and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
location = {{Lemgo}},
number = {{12}},
pages = {{52--57}},
publisher = {{Deut. Fachv.}},
title = {{{Was ist erlaubt, was verboten? 16. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost – 4. Teil}}},
volume = {{100}},
year = {{2021}},
}
@article{6927,
author = {{Upmann, Matthias and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
location = {{Lemgo}},
number = {{11}},
pages = {{48--50}},
publisher = {{Deut. Fachv.}},
title = {{{Was ist erlaubt, was verboten? 16. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost – 3. Teil}}},
volume = {{100}},
year = {{2021}},
}
@inbook{7095,
author = {{Schattenberg, Britta and Stake, Kirsten and Schneider, Jan}},
booktitle = {{Behr´s Jahrbuch für die Lebensmittelwirtschaft 2022}},
isbn = {{978-3-95468-810-4}},
publisher = {{Behr´s Verlag}},
title = {{{Einsatzmöglichkeiten von Allulose zur Kalorienreduktion in Biermischgetränken}}},
year = {{2021}},
}
@misc{7927,
author = {{Hernández Rodriguez, Tanja and Frahm, Björn}},
location = {{SeAMK, Seinäjoki, Finnland}},
title = {{{Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction}}},
year = {{2021}},
}
@misc{7931,
author = {{Moser, André and Möller, Johannes and Kuchemüller, Kim B. and Deppe, Sahar and Hernández Rodriguez, Tanja and Gassenmeier, Veronika and Ifrim, George Adrian and Frahm, Björn and Pörtner, Ralf and Hass, Volker C.}},
location = {{as a web conference, Prague, Czech Republic}},
title = {{{Model-assisted Design of Experiments - Concept, Software and Applications}}},
year = {{2021}},
}
@misc{7939,
author = {{Wirtanen, Gun and Alarinta, Jarmo and Frahm, Björn and Fasse, Sylvia}},
booktitle = {{MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science}},
title = {{{Bovine Colostrum for Human Consumption}}},
year = {{2021}},
}
@misc{7981,
abstract = {{The main purpose of bovine colostrum, being the milk secreted by a cow after giving birth, is to transfer passive immunity to the calf. The calves have an immature immune system as they lack immunoglobulins (Igs). Subsequently, the supply of good quality bovine colostrum is required. The quality of colostrum is classified by low bacterial counts and adequate Ig concentrations. Bacterial contamination can contain a variety of human pathogens or high counts of spoilage bacteria, which has become more challenging with the emerging use of bovine colostrum as food and food supplements. There is also a growing risk for the spread of zoonotic diseases originating from bovines. For this reason, processing based on heat treatment or other feasible techniques is required. This review provides an overview of literature on the microbial quality of bovine colostrum and processing methods to improve its microbial quality and keep its nutritional values as food. The highlights of this review are as follows: high quality colostrum is a valuable raw material in food products and supplements; the microbial safety of bovine colostrum is increased using an appropriate processing-suitable effective heat treatment which does not destroy the high nutrition value of colostrum; the heat treatment processes are cost-effective compared to other methods; and heat treatment can be performed in both small- and large-scale production.}},
author = {{Fasse, Sylvia and Alarinta, Jarmo and Frahm, Björn and Wirtanen, Gun}},
booktitle = {{Dairy}},
issn = {{2624-862X }},
keywords = {{bovine colostrum, bacteria, pathogens, probiotic bacteria, cost-effective processing, heat treatment, pasteurization, contamination control, immunoglobulins, enzymes}},
number = {{4}},
pages = {{556--575}},
publisher = {{MDPI}},
title = {{{Bovine Colostrum for Human Consumption - Improving Microbial Quality and Maintaining Bioactive Characteristics through Processing}}},
doi = {{10.3390/dairy2040044}},
volume = {{2}},
year = {{2021}},
}
@inbook{7983,
abstract = {{For the manufacturing of complex biopharmaceuticals using bioreactors with cultivated mammalian cells, high product concentration is an important objective. The phenotype of the cells in a reactor plays an important role. Are clonal cell populations showing high cell-specific growth rates more favorable than cell lines with higher cell-specific productivities or vice versa? Five clonal Chinese hamster ovary cell populations were analyzed based on the data of a 3-month-stability study. We adapted a mechanistic cell culture model to the experimental data of one such clonally derived cell population. Uncertainties and prior knowledge concerning model parameters were considered using Bayesian parameter estimations. This model was used then to define an inoculum train protocol. Based on this, we subsequently simulated the impacts of differences in growth rates (±10%) and production rates (±10% and ±50%) on the overall cultivation time, including making the inoculum train cultures; the final production phase, the volumetric titer in that bioreactor and the ratio of both, defined as overall process productivity. We showed thus unequivocally that growth rates have a higher impact (up to three times) on overall process productivity and for product output per year, whereas cells with higher productivity can potentially generate higher product concentrations in the production vessel.}},
author = {{Hernández Rodriguez, Tanja and Morerod, Sophie and Pörtner, Ralf and Wurm, Florian M. and Frahm, Björn}},
booktitle = {{Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing}},
isbn = {{978-3-0365-5210-1}},
issn = {{2227-9717 }},
keywords = {{clonal cell population, phenotypic diversity, inoculum train, uncertainty-based, cell culture model, biopharmaceutical manufacturing}},
pages = {{49--74}},
publisher = {{MDPI}},
title = {{{Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study}}},
doi = {{10.3390/pr9060964}},
volume = {{special issue}},
year = {{2021}},
}
@misc{11376,
abstract = {{concentration is an important objective. The phenotype of the cells in a reactor plays an important role. Are clonal cell populations showing high cell-specific growth rates more favorable than cell lines with higher cell-specific productivities or vice versa? Five clonal Chinese hamster ovary cell populations were analyzed based on the data of a 3-month-stability study. We adapted a mechanistic cell culture model to the experimental data of one such clonally derived cell population. Uncertainties and prior knowledge concerning model parameters were considered using Bayesian parameter estimations. This model was used then to define an inoculum train protocol. Based on this, we subsequently simulated the impacts of differences in growth rates (±10%) and production rates (±10% and ±50%) on the overall cultivation time, including making the inoculum train cultures; the final production phase, the volumetric titer in that bioreactor and the ratio of both, defined as overall process productivity. We showed thus unequivocally that growth rates have a higher impact (up to three times) on overall process productivity and for product output per year, whereas cells with higher productivity can potentially generate higher product concentrations in the production vessel.}},
author = {{Hernández Rodriguez, Tanja and Morerod, Sophie and Pörtner, Ralf and Wurm, Florian M. and Frahm, Björn}},
booktitle = {{Processes}},
issn = {{2227-9717}},
keywords = {{clonal cell population, phenotypic diversity, inoculum train, uncertainty-based, cell culture model, biopharmaceutical manufacturing}},
number = {{6}},
publisher = {{MDPI AG}},
title = {{{Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection—A Simulation Study}}},
doi = {{10.3390/pr9060964}},
volume = {{9}},
year = {{2021}},
}
@misc{7985,
abstract = {{Bioprocess modeling has become a useful tool for prediction of the process future with the aim to deduce operating decisions (e.g. transfer or feeds). Due to variabilities, which often occur between and within batches, updating (re-estimation) of model parameters is required at certain time intervals (dynamic parameter estimation) to obtain reliable predictions. This can be challenging in the presence of low sampling frequencies (e.g. every 24 h), different consecutive scales and large measurement errors, as in the case of cell culture seed trains. This contribution presents an iterative learning workflow which generates and incorporates knowledge concerning cell growth during the process by using a moving horizon estimation (MHE) approach for updating of model parameters. This estimation technique is compared to a classical weighted least squares estimation (WLSE) approach in the context of model updating over three consecutive cultivation scales (40–2160 L) of an industrial cell culture seed train. Both techniques were investigated regarding robustness concerning the aforementioned challenges and the required amount of experimental data (estimation horizon). It is shown how the proposed MHE can deal with the aforementioned difficulties by the integration of prior knowledge, even if only data at two sampling points are available, outperforming the classical WLSE approach. This workflow allows to adequately integrate current process behavior into the model and can therefore be a suitable component of a digital twin.}},
author = {{Hernández Rodriguez, Tanja and Posch, Christoph and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{Bioprocess and Biosystems Engineering}},
issn = {{1615-7605}},
keywords = {{Dynamic parameter estimation, Bioprocess, Cell cultures, Moving horizon estimation, Prior knowledge}},
number = {{4}},
pages = {{793--808}},
publisher = {{Springer}},
title = {{{Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train}}},
doi = {{10.1007/s00449-020-02488-1 }},
volume = {{44}},
year = {{2021}},
}
@misc{7986,
abstract = {{Bioprocess development and optimization are still cost- and time-intensive due to the enormous number of experiments involved. In this study, the recently introduced model-assisted Design of Experiments (mDoE) concept (Möller et al. in Bioproc Biosyst Eng 42(5):867, https://doi.org/10.1007/s00449-019-02089-7, 2019) was extended and implemented into a software (“mDoE-toolbox”) to significantly reduce the number of required cultivations. The application of the toolbox is exemplary shown in two case studies with Saccharomyces cerevisiae. In the first case study, a fed-batch process was optimized with respect to the pH value and linearly rising feeding rates of glucose and nitrogen source. Using the mDoE-toolbox, the biomass concentration was increased by 30% compared to previously performed experiments. The second case study was the whole-cell biocatalysis of ethyl acetoacetate (EAA) to (S)-ethyl-3-hydroxybutyrate (E3HB), for which the feeding rates of glucose, nitrogen source, and EAA were optimized. An increase of 80% compared to a previously performed experiment with similar initial conditions was achieved for the E3HB concentration.}},
author = {{Moser, André and Kuchemüller, Kim B. and Deppe, Sahar and Hernández Rodriguez, Tanja and Frahm, Björn and Pörtner, Ralf and Hass, Volker C. and Möller, Johannes}},
booktitle = {{Bioprocess and Biosystems Engineering}},
isbn = {{1615-7591}},
issn = {{1615-7605}},
keywords = {{Biocatalysis, Monte Carlo methods, Fed-batch strategy, Model-assisted design of experiments, Quality by design}},
number = {{4}},
pages = {{683--700}},
publisher = {{Springer}},
title = {{{Model-assisted DoE software: Optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses}}},
doi = {{10.1007/s00449-020-02478-3}},
volume = {{44}},
year = {{2021}},
}
@misc{8078,
author = {{Blome, André and Luttmann, Mario and Frahm, Björn and Müller, Ulrich}},
booktitle = {{Seminar Life Science Technologies 2021-04-28}},
location = {{Lemgo, Germany}},
title = {{{Messtechnikkonzepte für die Erfassung von qualitätsrelevanten Parametern und Merkmalen bei der Weizenteigverarbeitung}}},
year = {{2021}},
}
@inbook{3349,
abstract = {{Model-based concepts and simulation techniques in combination with digital tools emerge as a key to explore the full potential of biopharmaceutical production processes, which contain several challenging development and process steps. One of these steps is the time- and cost-intensive cell proliferation process (also called seed train) to increase cell number from cell thawing up to production scale. Challenges like complex cell metabolism, batch-to-batch variation, variabilities in cell behavior, and influences of changes in cultivation conditions necessitate adequate digital solutions to provide information about the current and near future process state to derive correct process decisions.
For this purpose digital seed train twins have proved to be efficient, which digitally display the time-dependent behavior of important process variables based on mathematical models, strategies, and adaption procedures.
This chapter will outline the needs for digitalization of seed trains, the construction of a digital seed train twin, the role of parameter estimation, and different statistical methods within this context, which are applicable to several problems in the field of bioprocessing. The results of a case study are presented to illustrate a Bayesian approach for parameter estimation and prediction of an industrial cell culture seed train for seed train digitalization.}},
author = {{Hernández Rodriguez, Tanja and Frahm, Björn}},
booktitle = {{Digital Twins Tools and Concepts for Smart Biomanufacturing}},
editor = {{Herwig, Christoph and Pörtner, Ralf and Möller, Johannes }},
isbn = {{978-3-030-71659-2}},
issn = {{1616-8542}},
keywords = {{Bayes, Digital twin, Parameter estimation, Seed train, Uncertainty}},
pages = {{97–131}},
publisher = {{Springer}},
title = {{{Digital Seed Train Twins and Statistical Methods}}},
doi = {{https://doi.org/10.1007/10_2020_137}},
volume = {{176}},
year = {{2021}},
}
@inproceedings{6158,
author = {{Müller, Ulrich and Blome, André and Luttmann, Mario}},
location = {{Bonn}},
title = {{{Ressourceneinsparung und Individualisierung bei Lebensmittelherstellungsprozessen mit Hilfe von Industrie-4.0-Methoden - Digitalisierung startet mit der Datenbeschaffung}}},
year = {{2021}},
}
@inproceedings{6171,
author = {{Schneider, Jan and Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich}},
location = {{Siegen}},
title = {{{Pasteurisation von Getränken: Verweilzeitverteilungen in der KZE und Chemischer Temperatur-Zeit-Indikator zur Prüfung von KZE-Anlagen}}},
year = {{2021}},
}
@misc{5423,
abstract = {{Preservation of juices is essential to obtain microbial safe products. There are various established methods as pasteurization. Heretofore, only the kinetic figures of microbial inactivation were considered but not those of reaction impairing the chemical quality. For a gentler processing, knowledge of the kinetics of relevant chemical conversion reactions is necessary. 5-(Hydroxymethyl)-furfural (HMF) formation and the color change of juices are important attributes. The non-isothermal Rhim method was used to determine the activation energy and pre-exponential factor for HMF formation in different juices and an isothermal method for the reaction order. Values for the activation energy from 133 to 303 kJ/mol were obtained with a zeroth reaction order. A correlation between HMF and the color change could be found. Based on the kinetic figures, lines with equal effects for the chemical changes and for the lethal effect on microorganisms were calculated. Time-temperature settings for the gentlest treatment could be found.}},
author = {{Katsch, Linda and Methner, Frank-Jürgen and Schneider, Jan}},
booktitle = {{International Journal of Food Engineering }},
issn = {{1556-3758}},
keywords = {{absorption at 420 nm, HMF, kinetic figures, line of equal effect, pasteurization.}},
number = {{9}},
pages = {{703--713}},
publisher = {{Walter de Gruyter GmbH}},
title = {{{Kinetic studies of 5-(Hydroxymethyl)-furfural formation and change of the absorption at 420 nm in fruit juices for the improvement of pasteurization plants }}},
doi = {{https://doi.org/10.1515/ijfe-2020-0324}},
volume = {{17}},
year = {{2021}},
}
@misc{5504,
author = {{Katsch, Linda and Schneider, Jan}},
booktitle = {{Brauwelt}},
issn = {{1439-5177}},
number = {{14}},
pages = {{340--343}},
publisher = {{Fachverlag Hans Carl GmbH}},
title = {{{Potential für eine schonendere Pasteurisation}}},
year = {{2021}},
}
@misc{12805,
abstract = {{n recent decades, the demand for palm oil has constantly increased and with it the cultivation of oil palms. After a period of 25 years, the oil yield of the palm trees decreases and they are felled. The trees are cut into pieces and remain on the plantations. However, due to their high moisture and sugar content, fungi and molds cause problems for replanting. The use of the wood for the timber industry is difficult due to its structural characteristics. Biotechnological processes use microorganisms to produce relevant industrial products. The basis for each process is a culture medium that contains all necessary nutrients, especially carbohydrates. The culture medium makes up a high percentage of the costs, so alternative, cheaper substrates are preferred. In this review, we show and compare different analyses of the sap mechanically pressed from the oil palm trunk regarding its sugar and nutrient content. The total sugar concentration in the palm sap varies between 16.97–140 g L−1 and it is mainly composed of glucose, fructose, and sucrose. The comparison with common nutrient media and the results of fermentation processes already carried out on a laboratory scale show that palm sap offers great potential as a fermentation medium for biotechnological conversion into industrially relevant products. }},
author = {{Dirkes, Rabea and Neubauer, Pia Rebecca and Rabenhorst, Jürgen}},
booktitle = {{Biofuels, Bioproducts and Biorefining}},
issn = {{1932-1031}},
keywords = {{oil palm, trunks, pressed sap, Elaeis guineensis, sugar, nutrients, review}},
number = {{3}},
pages = {{931--944}},
publisher = {{Wiley}},
title = {{{Pressed sap from oil palm (Elaeis guineensis) trunks: a revolutionary growth medium for the biotechnological industry?}}},
doi = {{10.1002/bbb.2201}},
volume = {{15}},
year = {{2021}},
}
@misc{12950,
abstract = {{The composition of the microbiome is subject to the host’s diet. In commercial laboratory mouse diets, different physical forms of the same diets are available, containing—according to their labels—identical ingredients and nutrient compositions. However, variations in nutrient composition and starch gelatinization due to production processes and their impact on digestibility have been described. In this study, a total of 48 C57BL/J6 mice were assigned to two equal groups and were fed diets (produced with different processes—extruded vs. pelleted) for eight weeks in two biological replicates. At the end of the experiment, samples were collected from five different gastrointestinal regions, including the stomach, small intestine, cecum, large intestine, and an extracorporeal region (feces), and the microbiome was analyzed with 16S rRNA gene amplicon sequencing. The replicates in both experiments differed significantly in their relative abundances of Muribaculaceae species. Furthermore, the gastrointestinal content of pellet-fed mice contained larger numbers of Lactobacillus species. These results indicate that starch gelatinization and ingredient composition significantly influence microbial makeup. In conclusion, different feed processing methods may affect fundamental digestive and metabolic processes, impacting animal experiments and biasing microbiome data.}},
author = {{Wenderlein, Jasmin and Böswald, Linda F. and Ulrich, Sebastian and Kienzle, Ellen and Neuhaus, Klaus and Lagkouvardos, Ilias and Zenner, Christian and Straubinger, Reinhard K.}},
booktitle = {{Animals}},
issn = {{2076-2615}},
keywords = {{feed processing, starch gelatinization, laboratory mouse, diet, intestinal microbiome}},
number = {{3}},
publisher = {{MDPI AG}},
title = {{{Processing Matters in Nutrient-Matched Laboratory Diets for Mice—Microbiome}}},
doi = {{10.3390/ani11030862}},
volume = {{11}},
year = {{2021}},
}
@misc{12951,
abstract = {{Leptospirosis is a neglected worldwide zoonotic bacterial disease with a high prevalence in subtropical and tropical countries. The prevalence of Leptospira spp. in humans, cattle and dogs is unknown in Bhutan. Therefore, we sought to find out whether humans, cattle or dogs had been infected in the past with leptospires by measuring antibodies in the serum. We therefore collected blood from 864 humans ≥13 years of age, 130 bovines and 84 dogs from different rural and urban areas in Bhutan and tested the serum for antibodies specific for leptospires with a screening of enzyme-linked immunosorbent assays (ELISA) and a confirmatory microscopic agglutination test (MAT). In humans, 17.6% were seropositive by ELISA and 1.6% by MAT. The seropositivity was stronger in bovines (36.9%) and dogs (47.6%). “Having had a fever recently” (OR 5.2, p = 0.004), “working for the military” (OR 26.6, p = 0.028) and “being unemployed” (OR 12.9, p = 0.041) (reference category = housemaker) were statistically significantly associated with seropositivity when controlled for the effects of other risk factors. However, due to the small number of positive test results, the findings on risk factors should be interpreted with caution. Based on the serogroups found in the three species, dogs could be a source of infection for humans, or dogs and humans are exposed to the same environmental risk factors Clinical leptospirosis in humans and domestic animals should be investigated by testing blood and urine for the presence of leptospires by molecular methods (qPCR).}},
author = {{Dreyfus, Anou and Ruf, Marie-Thérèse and Mayer-Scholl, Anne and Zitzl, Theresa and Loosli, Nadine and Bier, Nadja Seyhan and Hiereth, Stephanie and Ulrich, Sebastian and Poppert, Sven and Straubinger, Reinhard K. and Stenos, John and Tshokey, Tshokey}},
booktitle = {{Pathogens}},
issn = {{2076-0817}},
keywords = {{leptospirosis, microscopic agglutination test (MAT), seroprevalence, cattle, yak, dog, one health, Bhutan}},
number = {{3}},
publisher = {{MDPI}},
title = {{{Exposure to Leptospira spp. and Associated Risk Factors in the Human, Cattle and Dog Populations in Bhutan}}},
doi = {{10.3390/pathogens10030308}},
volume = {{10}},
year = {{2021}},
}
@misc{12952,
abstract = {{Straw is the main by-product of grain production, used as bedding material and animal feed. If produced or stored under adverse hygienic conditions, straw is prone to the growth of filamentous fungi. Some of them, e.g. Aspergillus, Fusarium and Stachybotrys spp. are well-known mycotoxin producers. Since studies on mycotoxins in straw are scarce, 192 straw samples (wheat n = 80; barley n = 79; triticale n = 12; oat n = 11; rye n = 12) were collected across Germany within the German official feed surveillance and screened for the presence of 21 mycotoxins. The following mycotoxins (positive samples for at least one mycotoxin n = 184) were detected: zearalenone (n = 86, 6.0–785 μg/kg), nivalenol (n = 51, 30–2,600 μg/kg), deoxynivalenol (n = 156, 20–24,000 μg/kg), 15-acetyl-deoxynivalenol (n = 34, 20–2,400 μg/kg), 3-acetyl-deoxynivalenol (n = 16, 40–340 μg/kg), scirpentriol (n = 14, 40–680 μg/kg), T-2 toxin (n = 67, 10–250 μg/kg), HT-2 toxin (n = 92, 20–800 μg/kg), T-2 tetraol (n = 13, 70–480 μg/kg). 15-monoacetoxyscirpenol (30 μg/kg) and T-2 triol (60 μg/kg) were only detected in one barley sample. Macrocyclic trichothecenes (satratoxin G, F, roridin E, and verrucarin J) were also found in only one barley sample (quantified as roridin A equivalent: total 183 μg/kg). The occurrence of stachybotrylactam was monitored for the first time in four samples (n = 4, 0.96–7.4 μg/kg). Fusarenon-X, 4,15-diacetoxyscirpenol, neosolaniol, satratoxin H and roridin-L2 were not detectable in the samples. The results indicate a non-negligible contribution of straw to oral and possibly inhalation exposure to mycotoxins of animals or humans handling contaminated straw.}},
author = {{Ulrich, Sebastian and Gottschalk, Christoph and Biermaier, Barbara and Bahlinger, Eunike and Twarużek, Magdalena and Asmussen, Sarah and Schollenberger, Margit and Valenta, Hana and Ebel, Frank and Dänicke, Sven}},
booktitle = {{Archives of animal nutrition = Archiv für Tierernährung}},
issn = {{1477-2817}},
keywords = {{Fusarium, mycotoxins, stachybotrylactam, stachybotrys, straw, trichothecenes, zearalenone}},
number = {{2}},
pages = {{105--120}},
publisher = {{Taylor & Francis }},
title = {{{Occurrence of type A, B and D trichothecenes, zearalenone and stachybotrylactam in straw}}},
doi = {{10.1080/1745039x.2021.1877075}},
volume = {{75}},
year = {{2021}},
}
@misc{12953,
abstract = {{Starch gelatinization is a major determinant of carbohydrate digestibility and varies with diet processing. Laboratory rodent diets are often marketed as identical, but are sold in different forms, regardless of the markedly higher starch gelatinization in extruded than in pelleted diets. Our hypothesis was that this would impact energy and nutrient digestibility in mice fed pellets or extrudate, respectively. Trial 1 showed that feeding C57BL/6 mice a standard maintenance diet in extruded form results in a significantly higher digestibility of organic matter, energy, and carbohydrates than the identical diet in pelleted form. The replication of the experiment, however, revealed a variation between batches of the same pelleted diet regarding starch and total dietary fiber contents. Given the significant differences in diet digestibility and the potential impacts of digestibility on nutrient utilization, the intestinal microbiome, and intermediary metabolism, trials performed with differently processed diets are not comparable. This might partly explain failures to reproduce results, especially in gastrointestinal or microbiome research. Considering this impact on experimental animals, the degree of starch gelatinization should be declared in the diet information for laboratory animal diets. The differences between batches of laboratory animal diets as observed in the pellets are not acceptable.}},
author = {{Böswald, Linda F. and Wenderlein, Jasmin and Straubinger, Reinhard K. and Ulrich, Sebastian and Kienzle, Ellen}},
booktitle = {{Animals}},
issn = {{2076-2615}},
keywords = {{standardization, carbohydrate digestibility, feed processing, starch gelatinization, gut}},
number = {{2}},
publisher = {{MDPI}},
title = {{{Processing Matters in Nutrient-Matched Laboratory Diets for Mice—Energy and Nutrient Digestibility}}},
doi = {{10.3390/ani11020523}},
volume = {{11}},
year = {{2021}},
}
@misc{12954,
abstract = {{Stachybotrys (S.) chartarum is a cellulolytic mould with the ability to produce highly cytotoxic macrocyclic trichothecenes. Two chemotypes are defined according to their ability to produce either atranones or satratoxins. S. chartarum has been well known as the causative agent of the lethal disease stachybotryotoxicosis in horses. Further investigations revealed that this disease is strictly correlated with the presence of macrocyclic trichothecenes. Furthermore, their occurrence in water-damaged buildings has been linked to adverse health effects such as the sick building syndrome. As the chemotypes cannot be characterized via phenotypic criteria, different methods such as PCR, MALDI–TOF MS, LC–MS/MS, thin-layer chromatography and cytotoxicity assays have been used so far. Fourier-transform-infrared spectroscopy (FT-IR) is commonly used for the differentiation of bacteria and yeasts, but this technique is also applicable to filamentous fungi. Hence, this study aimed at evaluating to which extent a reliable differentiation of S. chartarum chemotypes A and S is possible. Besides, another objective was to verify if the recently introduced third genotype of S. chartarum can be identified. Therefore, 28 strains including the two chemotypes and the third genotype H were cultivated on malt extract agar (MEA) and potato dextrose agar in three biological replicates. Each sample was applied to FT-IR measurements on day 7, 14 and 21 of cultivation. In this study, we achieved a distinction of the chemotypes A and S via FT-IR spectroscopy after incubation for 7 days on MEA. In terms of genotype differentiation, the PCR detecting satratoxin- and atranone-gene clusters remained the only applicable method.}},
author = {{Ekruth, Julia and Gottschalk, Christoph and Ulrich, Sebastian and Gareis, Manfred and Schwaiger, Karin}},
booktitle = {{Mycopathologia}},
issn = {{1573-0832}},
keywords = {{Aspergillus nidulans, Fungal biology, Gas chromatography, Pseudomonas fluorescens, Western Blot, Bacillus subtilis}},
number = {{6}},
pages = {{993--1004}},
publisher = {{Springer }},
title = {{{Differentiation of S. chartarum (Ehrenb.) S. Hughes Chemotypes A and S via FT-IR Spectroscopy}}},
doi = {{10.1007/s11046-020-00495-0}},
volume = {{185}},
year = {{2021}},
}
@misc{12958,
abstract = {{Cytotoxic macrocyclic trichothecenes such as satratoxins are produced by chemotype S strains of Stachybotrys chartarum. Diseases such as stachybotryotoxicosis in animals and the sick building syndrome as a multifactorial disease complex in humans have been associated with this mold and its toxins. Less toxic non-chemotype S strains of S. chartarum are morphologically indistinguishable from chemotype S strains, which results in uncertainties in hazard characterization of isolates. To selectively identify macrocyclic trichothecene producing S. chartarum isolates, a set of sat14 gene-specific primers was designed and applied in a loop-mediated isothermal amplification (LAMP) assay using neutral red for visual signal detection. The assay was highly specific for S. chartarum strains of the macrocyclic trichothecene producing chemotype and showed no cross-reaction with non-macrocyclic trichothecene producing S. chartarum strains or 152 strains of 131 other fungal species. The assay’s detection limit was 0.635 pg/rxn (picogram per reaction) with a reaction time of 60 min. Its high specificity and sensitivity as well as the cost-saving properties make the new assay an interesting and powerful diagnostic tool for easy and rapid testing.}},
author = {{Köck, Johannes and Gottschalk, Christoph and Ulrich, Sebastian and Schwaiger, Karin and Gareis, Manfred and Niessen, Ludwig}},
booktitle = {{Analytical and bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry and Analusis}},
issn = {{1618-2650}},
keywords = {{Aspergillus nidulans, Basidiomycetes, Fungi, Strigolactone, Liquid chromatography, Solid-phase microextraction}},
number = {{19}},
pages = {{4801--4813}},
publisher = {{Springer }},
title = {{{Rapid and selective detection of macrocyclic trichothecene producing Stachybotrys chartarum strains by loop-mediated isothermal amplification (LAMP)}}},
doi = {{10.1007/s00216-021-03436-y}},
volume = {{413}},
year = {{2021}},
}
@misc{12961,
abstract = {{Zu den Zecken-übertragenen Erkrankungen beim Pferd in Deutschland zählen neben der Equinen Granulozytären Anaplasmose (EGA, verursacht durch Anaplasma phagocytophilum, Ap) auch die Equine Lyme-Borreliose (verursacht durch den Borrelia-burgdorf-eri-sensu-lato-Komplex), die Frühsommer-Meningoencephalitis (FSME-Virus) und die Equine Piroplasmose (Babesia caballi, Theileria equi). Die EGA ist nicht kontagiös, so dass in der Regel innerhalb eines Bestandes nur einzelne Pferde betroffen sind. Der Schweregrad der Erkrankung ist vom Alter des Pferdes und der Dauer der Erkrankung abhängig. Zumeist tritt Apathie und Fieber auf. Jüngere Pferde (< 4 Jahre) entwickeln meist nur mildere klinische Veränderungen als ältere Pferde. In den meisten Fällen weist die EGA bei jungen Pferden und vor allem in Endemiegebieten,
einen subklinischen oder milden Verlauf auf. Als Erregerreservoir dienen vor allem kleine wildlebende Säuger wie z.B. Nagetiere. Die Diagnose der EGA basiert auf der epizootischen Anamnese (jahreszeitlich und regional typisches Auftreten, vorhandene Zeckenexposition) sowie klinischen und labordiagnostischen Befunden. Der direkte Erregernachweis erfolgt durch Teilgensequenzierung, direkten mikroskopischen Nachweis oder Kultivierung. Auch indirekte Erregernachweisverfahren zur Diagnose der EGA in Form serologischer Laboruntersuchungen (Morulae bzw. Einschlusskörperchen) stehen zur Verfügung. Dabei kommen in der Regel ELISAs und Immunfluoreszenztests zum Einsatz. Ein Anstieg der Antikörperspiegel um das vierfache Niveau, lässt eine sichere Diagnose zu. Spezifische Antikörper gegen Ap können ab dem 14. Tag post infectionem und bis zu zwei Jahre später nachgewiesen werden. Die EGA kann effektiv mit Antibiotika behandelt werden. Dadurch wird die Erkrankungsdauer signifikant verkürzt und die Schwere der Erkrankung gemindert. Da Ap ein intrazelluläres Pathogen ist, sind Tetrazykline die Antibiotika der Wahl (Oxytetrazyklin intravenös in einer Dosis von 7 mg/kg Körpergewicht einmal täglich über 5–7 Tage). Da bisher keine Impfung gegen die EGA zur Verfügung steht, sind die Prophylaxe-Maßnahmen auf die Verhinderung oder Minderung einer Zeckenexposition beschränkt.}},
author = {{Gehlen, Heidrun and Inerle, Katharina and Ulrich, Sebastian and Lehmann, Beatrice and Straubinger, Reinhard K.}},
booktitle = {{Pferdeheilkunde Equine Medicine}},
issn = {{2943-1794}},
keywords = {{Pferd, Anaplasmose, Infektion, Diagnostik, Prävention}},
number = {{1}},
pages = {{25--33}},
publisher = {{Hippiatrika GmbH}},
title = {{{Anaplasmose beim Pferd – Ein Literaturreview unter Berücksichtigung aktueller Diagnose- und Therapieverfahren H. Gehlen et al. Pferdeheilkunde – Equine Medicine 37 (2021)25 Pferdeheilkunde – Equine Medicine 37 (2021) 1 (Januar/Februar) 25–33 Anaplasmose beim Pferd – Ein Literaturreview unter Berücksichtigung aktueller Diagnose- und Therapie- verfahren sowie möglicher Präventionsmaßnahmen}}},
doi = {{10.21836/PEM20210104}},
volume = {{37}},
year = {{2021}},
}
@article{6571,
author = {{Upmann, Matthias}},
isbn = {{0178-2010}},
journal = {{Rundschau für Fleischhygiene und Lebensmittelüberwachung}},
number = {{1}},
pages = {{5--6}},
publisher = {{Presse Dienstleistungsges. }},
title = {{{Separatorenfleisch oder nicht? Konzept zur Einordnung von Geflügelrohstoffen}}},
year = {{2020}},
}
@misc{6572,
author = {{Upmann, Matthias}},
booktitle = {{Neue Westfälische}},
title = {{{Wissenschaftler kritisiert Bauern-Bashing}}},
year = {{2020}},
}
@misc{7929,
author = {{Hernández Rodriguez, Tanja and Deppe, Sahar and Gassenmeier, Veronika and Kuhfuß, Fabian and Tölle, Marius and Ifrim, George Adrian and Frahm, Björn}},
location = {{als Web-Konferenz, Aachen, Germany}},
title = {{{Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration}}},
year = {{2020}},
}
@misc{7930,
author = {{Hernández Rodriguez, Tanja and Posch, Christoph and Pörtner, Ralf and Frahm, Björn}},
location = {{als Web-Konferenz, Aachen, Germany}},
title = {{{Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes}}},
year = {{2020}},
}
@misc{7936,
author = {{Hernández Rodriguez, Tanja and Frahm, Björn and Posch, Christoph}},
location = {{Sandoz, Austria}},
title = {{{Integration of prior knowledge and digital tools for uncertainty-based decision support}}},
year = {{2020}},
}
@misc{7937,
author = {{Hernández Rodriguez, Tanja and Deppe, Sahar and Gassenmeier, Veronika and Kuhfuß, Fabian and Tölle, Marius and Ifrim, George Adrian and Frahm, Björn}},
booktitle = {{Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020}},
pages = {{1225 – 1226}},
publisher = {{Wiley}},
title = {{{Modeling of Chlorella vulgaris algae in shake flasks with respect to light intensity and light duration}}},
doi = {{10.1002/cite.202055235}},
volume = {{No. 9}},
year = {{2020}},
}
@misc{7938,
author = {{Hernández Rodriguez, Tanja and Posch, Christoph and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020}},
pages = {{1241 – 1242}},
publisher = {{Wiley}},
title = {{{Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes}}},
doi = {{10.1002/cite.202055234}},
volume = {{No. 9}},
year = {{2020}},
}
@inproceedings{1991,
author = {{Funk, Mark and Scharf, Matthias and Dörksen, Helene and Danneel, Hans-Jürgen and Lohweg, Volker and Hübner, Michael and Schaede, Johannes and Stierman, Rob and Knobloch, Alexander and Le, Dinh Khoi and Gillich, Eugen and Mönks, Uwe}},
booktitle = {{ODS 2020 Review}},
location = {{San Francisco}},
title = {{{Creating a Self-authentication System for Smart Banknotes}}},
year = {{2020}},
}
@misc{2392,
author = {{Möller, Johannes and Hernández Rodríguez, Tanja and Müller, Jan and Arndt, Lukas and Kuchemüller, Kim B. and Frahm, Björn and Eibl, Regine and Eibl, Dieter and Pörtner, Ralf}},
booktitle = {{Computers & Chemical Engineering}},
issn = {{0098-1354}},
pages = {{1--13}},
publisher = {{Elsevier}},
title = {{{Model uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processes}}},
doi = {{10.1016/j.compchemeng.2019.106693}},
volume = {{134}},
year = {{2020}},
}
@inbook{2397,
author = {{Hernández Rodríguez, Tanja and Frahm, Björn}},
booktitle = {{Animal Cell Biotechnology - Methods and Protocols}},
editor = {{Pörtner, Ralf}},
isbn = {{978-1-07-160190-7}},
issn = {{1064-3745}},
pages = {{251--267}},
publisher = {{Springer}},
title = {{{Design, Optimization and Adaptive Control of Cell Culture Seed Trains}}},
doi = {{10.1007/978-1-0716-0191-4_14}},
volume = {{2095}},
year = {{2020}},
}
@inbook{2399,
author = {{Deppe, S. and Frahm, Björn and Hass, V. C. and Hernández Rodríguez, T. and Kuchemüller, K. B. and Möller, J. and Pörtner, R.}},
booktitle = {{Animal Cell Biotechnology: Methods and Protocols}},
editor = {{Pörtner, Ralf}},
isbn = {{978-1-07-160190-7}},
issn = {{1064-3745}},
pages = {{213--234}},
publisher = {{Springer}},
title = {{{Estimation of Process Model Parameters}}},
doi = {{10.1007/978-1-0716-0191-4_12}},
volume = {{2095}},
year = {{2020}},
}
@misc{2822,
author = {{Hernández Rodriguez, Tanja and Posch, Christoph and Schmutzhard, Julia and Stettner, Josef and Weihs, Claus and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{BMC Proceedings}},
issn = {{1753-6561}},
location = {{Copenhagen, Denmark.}},
pages = {{P408}},
publisher = {{BioMed Central}},
title = {{{Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach}}},
doi = {{10.1186/s12919-020-00188-y}},
volume = {{14}},
year = {{2020}},
}
@misc{3007,
author = {{Kuhfuß, F. and Tölle, M. and Hernández Rodriguez, Tanja and Gassenmeier, Veronika and Deppe, S. and Ifrim, George Adrian and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration}}},
year = {{2020}},
}
@misc{3008,
author = {{Deppe, S. and Kuhfuß, F. and Tölle, M. and Hernández Rodriguez, Tanja and Gassenmeier, Veronika and Ifrim, George Adrian and Möller, J. and Pörtner, R. and Moser, A. and Hass, V. C. and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{Model-assisted Design of Experiments for algae cultivation}}},
year = {{2020}},
}
@misc{3009,
author = {{Ifrim, George Adrian and Deppe, S. and Hernández Rodriguez, Tanja and Gassenmeier, Veronika and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{Modeling of microalgae in an air-lift photobioreactor for biomass production}}},
year = {{2020}},
}
@misc{5418,
abstract = {{Pasteurization especially high-temperature short time (HTST) heating is a widely used preservation method which inactivates microorganisms and enzymes, but also degrades compounds as L-ascorbic acid. For a gentle dimensioning of a pasteurization plant the knowledge of the kinetic figures is important. Activation energy, reaction order and pre-exponential factor of the L-ascorbic acid degradation in a model solution, apple, orange and black currant juice were determined. Lines of equal effects, which indicate different time-temperature combinations for the degradation, could be derived and compared with the lethal effect on microorganisms. The activation energies were located in the area of 25 to 44 kJ/mol for all samples except of orange juice (74 kJ/mol) in the range of 40-90 ?C with a zeroth reaction order. Based on these values, the lines of equal effects showed a lesser degradation at higher temperatures and shorter holding times even in the typical setting range of pasteurization plants.}},
author = {{Katsch, Linda and Methner, F.-J. and Schneider, Jan}},
booktitle = {{BrewingScience}},
issn = {{1613-2041}},
number = {{7/8}},
pages = {{85 -- 94}},
publisher = {{Fachverlag Hans Carl GmbH}},
title = {{{Kinetic studies of L-ascorbic acid degradation in fruit juices for the improvement of pasteurization plants}}},
doi = {{https://doi.org/10.23763/BrSc20-13katsch}},
volume = {{73}},
year = {{2020}},
}
@article{5419,
abstract = {{Continuous mashing provides advantages compared to conventional batch-wise mashing in terms of space time yield. The majority of fermentable sugars are generated during the so-called “β-amylase rest” (62–64 ◦C). These low molecular sugars are fermented later in the brewing process by yeasts and therefore determine the beer attenuation degree. Biological malt variations complicate the application of a continuous system in industrial scale particularly concerning targeted quality parameters. The aim is the prediction of sugar formation from process parameters for a real time control system. Therefore, a semi-empirical model for sugar formation in a continuous stirred tank reactor (CSTR) system was developed under incorporation of the residence time distri- bution (RTD). The here presented model, which focuses on the “β-amylase rest”, is able to predict fermentable sugar concentrations in the continuous “β-amylase rest” with sufficient accuracy, in contrast to models that only use the flow rate and the reactor volume to determine the reaction time. However, the precision and trueness depend on the quality of the empirical data acquired previously in laboratory experiments for the selected temperature and raw material quality.}},
author = {{Wefing, Patrick and Conradi, Florian and Trilling-Haasler, Marc and Neubauer, Peter and Schneider, Jan}},
journal = {{Biochemical Engineering Journal }},
keywords = {{Continuous mashing, Residence time distribution, Beer, Enzyme bioreactor, Maltose rest}},
title = {{{Approach for modelling the extract formation in continuous conducted "beta-amylase rest" as part of the production of beer mash with targeted sugar content}}},
doi = {{10.1016/j.bej.2020.107765}},
volume = {{164}},
year = {{2020}},
}
@article{5420,
author = {{Schattenberg, Britta and Stake, Kirsten and Schneider, J.}},
journal = {{Flüssiges Obst}},
number = {{6}},
pages = {{200 -- 203}},
title = {{{Allulose als alternativer Zucker zur Kalorienreduktion in Nektaren}}},
year = {{2020}},
}
@inbook{5421,
author = {{Schattenberg, Britta and Stake, Kirsten and Schneider, J.}},
booktitle = {{Behr`s Jahrbuch für die Lebensmittelwirtschaft 2021}},
pages = {{97 -- 108}},
title = {{{Allulose - Alternativer Zucker zu Kalorienreduktion in Erfrischungsgetränken}}},
year = {{2020}},
}
@article{5422,
author = {{Schattenberg, Britta and Stake, Kirsten and Schneider, J.}},
journal = {{Fruit Processing}},
number = {{7}},
pages = {{222 -- 225}},
title = {{{Allulose as alternative sugar for calorie reduction in nectars}}},
year = {{2020}},
}
@article{5424,
abstract = {{Near infrared spectroscopy in combination with a transflection probe was investigated as inline measurement in a continuous flash pasteurizer system with a sugar-water model solution. Robustness and reproducibility of fluctuations of recorded spectra as well as trueness of the chemometric analysis were compared under different process parameter settings. Variable parameters were the flow rate (from laminar flow at 30 L/h to turbulent flow at 90 L/h), temperature (20 to 100 degrees C) and the path length of the transflection probe (2 and 4 mm) while the pressure was kept constant at 2.5 bar. Temperature and path length were identified as the most affecting parameters, in case of homogenous test medium. In case of particle containing systems, the flow rate could have an impact as well. However, the application of a PLS model, which includes a broad temperature range, and the correction of prediction results by applying a polynomial regression function for prediction errors, was able to compensate these effects. Also, a path length of 2 mm leads to a higher accuracy. The applied strategy shows that by the identification of relevant process parameters and settings as well as the establishment of a compensation strategy, near infrared spectroscopy is a powerful process analytical tool for continuous flash pasteurization systems.}},
author = {{Weishaupt, Imke and Zimmer, Manuel and Neubauer, Peter and Schneider, Jan}},
isbn = {{0022-1147}},
issn = {{1750-3841}},
journal = {{Journal of Food Science}},
keywords = {{flash pasteurization, inline near infrared spectroscopy, multivariate data analysis, process condition influences, sugar-water-solution model beverage}},
number = {{7}},
pages = {{2020 -- 2031}},
title = {{{Model based optimization of transflection near infrared spectroscopy as a process analytical tool in a continuous flash pasteurizer}}},
doi = {{10.1111/1750-3841.15307}},
volume = {{85}},
year = {{2020}},
}
@inproceedings{5426,
author = {{Zimmer, Manuel and Schneider, Jan}},
location = {{Lemgo}},
title = {{{Thermal pasteurisationof food in glass containers –Near Infrared studies as groundwork for cyber-physical systems}}},
year = {{2020}},
}
@inproceedings{5427,
author = {{Wefing, Patrick and Conradi, C. and Beckhoff, St.-Bumke}},
title = {{{Auf dem Weg zur Smart FOODFACTORY, Prototyp einer kontinuierlichen Maisch Anlage}}},
year = {{2020}},
}
@article{5428,
author = {{Schneider, Jan and Beckhoff-Bumke, S. and Ali, W.}},
journal = {{elektroniknet.de}},
title = {{{Digitalisierung - Bierbrauen 4.0}}},
year = {{2020}},
}
@article{5429,
author = {{Wefing, Patrick and Conradi, Florian and Trilling-Haasler, Marc and Schuster, Rudolf and Gossen, Arthur and Schneider, Jan}},
journal = {{Brauwelt}},
number = {{15 - 16}},
pages = {{413 -- 416}},
publisher = {{Carl Hanser Verlag}},
title = {{{Maischen 4.0 – kontinuierliche Maischanlage}}},
year = {{2020}},
}
@misc{12787,
abstract = {{Vapor phase hydrogen peroxide (H2O2) can be utilized to inactivate murine norovirus (MNV), a surrogate of human norovirus, on surface areas. However, vapor phase H2O2 inactivation of virus on fruits and vegetables has not been characterized. In this study, MNV was used to determine whether vaporized H2O2 inactivates virus on surfaces of various fruits and vegetables (apples, blueberries, cucumbers, and strawberries). The effect of vapor phase H2O2 decontamination was investigated with two application systems. Plaque assays were performed after virus recovery from untreated and treated fresh produce to compare the quantity of infective MNV. The Mann-Whitney U test was applied to the test results to evaluate the virus titer reductions of treated food samples, with significance set at P <= 0.05. The infective MNV populations were significantly reduced on smooth surfaces by 4.3 log PFU (apples, P < 0.00001) and 4 log PFU or below the detection limit (blueberries, P = 0.0074) by treatment with vapor phase H2O2 (60 min, maximum of 214 ppm of H2O2). Similar treatments of artificially contaminated cucumbers resulted in a virus titer reduction of 1.9 log PFU. Treatment of inoculated strawberries resulted in 0.1and 2.8-log reductions of MNV. However, MNV reduction rates on cucumbers (P = 0.3809) and strawberries (P = 0,7414) were not significant. Triangle tests and color measurements of untreated and treated apples, cucumbers, blueberries, and strawberries revealed no differences in color and consistency after H2O2 treatment. No increase of the H2O2 concentration in treated fruits and vegetables compared with untreated produce was observed. This study reveals for the first time the conditions under which vapor phase H2O2 inactivates MNV on selected fresh fruit and vegetable surfaces.}},
author = {{Becker, Barbara and Dabisch-Ruthe, Mareike and Pfannebecker, Jens}},
booktitle = {{ Journal of food protection }},
issn = {{1944-9097}},
keywords = {{Fruits, Inactivation, Murine norovirus, Vapor phase hydrogen peroxide, Vegetables}},
number = {{1}},
pages = {{45--51}},
publisher = {{IAFP}},
title = {{{Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide}}},
doi = {{10.4315/0362-028X.JFP-19-238}},
volume = {{83}},
year = {{2020}},
}
@misc{12955,
abstract = {{Ein 10 Monate alter, männlich intakter Rhodesian Ridgeback wurde wegen chronischen Dickdarmdurchfalls und Hämatochezie vorgestellt. Der Hund stammte aus Deutschland und hatte das Land nie verlassen. Die Laboruntersuchung des vorbehandelnden Tierarztes ergab neben einer Neutrophilie eine Hyperkaliämie und eine Hyponatriämie. Mit einem Serumbasalkortisolwert von 4,3 µg/dl konnte ein Hypoadrenokortizismus weitgehend ausgeschlossen werden. Eine vom Tierarzt durch geführte antibiotische Behandlung hatte keine Besserung bewirkt. Daher war der Hund mit Prednisolon behandelt worden. Unter 2-wöchiger Prednisolongabe kam es zu einer deutlichen Verstärkung des Durchfalls sowie einem Gewichtsverlust von 6 kg. Bei Vorstellung an der Medizinischen Kleintierklinik der LMU München war der Hund im Allgemeinbefinden mittelgradig reduziert, deutlich abgemagert, dehydriert, hypovolämisch und hatte eine rektale Körpertemperatur von 39,6 °C. Bei der sonografischen Untersuchung zeigte sich eine generalisiert verdickte Dickdarmwand und koloskopisch eine hochgradig ulzerativ veränderte Dickdarmschleimhaut. Histologischer Befund war eine ulzerative granulomatöse Kolitis. Durch die Periodic-Acid-Schiff-Reaktion ließen sich in den Schnitten der Dickdarmbioptate mikrobielle Strukturen darstellen, die für eine Algeninfektion diagnostisch waren. Die bei der mikrobiellen Untersuchung anzüchtbaren Prototheken wurden mittels MALDI-TOF-MS als Prototheca zopfii identifiziert. Zum Nachweis einer möglichen Immundefizienz wurden die Immunglobuline im Serum bestimmt. Die IgM-Konzentration war erniedrigt, während sich IgG- und IgA-Konzentration im Referenzbereich befanden. Aufgrund der Verschlechterung des Allgemeinbefindens, der vorsichtigen Prognose und der hohen Kosten eines Therapieversuchs wurde der Hund eine Woche später euthanasiert und der Tierkörper pathologisch untersucht. Histopathologisch wurden Prototheken auch in den abdominalen Lymphknoten, jedoch nicht in den Augen oder im zentralen Nervensystem identifiziert. Der Fall zeigt, dass eine Prototheken-Infektion auch bei Hunden aus Deutschland als Differenzialdiagnose für chronischen Dickdarmdurchfall in Betracht gezogen werden sollte, insbesondere bei Patienten mit ulzerativer granulomatöser Kolitis. Sie kann bei der histologischen Untersuchung ohne Spezialfärbung leicht übersehen werden.}},
author = {{Geisen, Vera and Mayer, Christian and Harrer, Julia and Hartmann, Katrin and Ulrich, Sebastian and Unterer, Stefan}},
booktitle = {{Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere}},
issn = {{2567-5842}},
keywords = {{Hund - Algeninfektion - chronischer Durchfall - Protothekose - Prototheca zopfii}},
number = {{05}},
pages = {{369--375}},
publisher = {{Thieme }},
title = {{{Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland}}},
doi = {{10.1055/a-1238-1554}},
volume = {{48}},
year = {{2020}},
}
@misc{12956,
abstract = {{Stachybotrys (S.) chartarum had been linked to severe health problems in humans and animals, which occur after exposure to the toxic secondary metabolites of this mold. S. chartarum had been isolated from different environmental sources, ranging from culinary herbs and improperly stored fodder to damp building materials. To access the pathogenic potential of isolates, it is essential to analyze them under defined conditions that allow for the production of their toxic metabolites. All Stachybotrys species are assumed to produce the immunosuppressive phenylspirodrimanes, but the highly cytotoxic macrocyclic trichothecenes are exclusively generated by the genotype S of S. chartarum. In this study, we have analyzed four genotype S strains initially isolated from three different habitats. We grew them on five commonly used media (malt-extract-agar, glucose-yeast-peptone-agar, potato-dextrose-agar, cellulose-agar, Sabouraud-dextrose-agar) to identify conditions that promote mycotoxin production. Using LC-MS/MS, we have quantified stachybotrylactam and all S-type specific macrocyclic trichothecenes (satratoxin G, H, F, roridin E, L-2, verrucarin J). All five media supported a comparable fungal growth and sporulation at 25 °C in the dark. The highest concentrations of macrocyclic trichothecenes were detected on potato-dextrose-agar or cellulose-agar. Malt-extract-agar let to an intermediate and glucose-yeast-peptone-agar and Sabouraud-dextrose-agar to a poor mycotoxin production. These data demonstrate that the mycotoxin production clearly depends on the composition of the respective medium. Our findings provide a starting point for further studies in order to identify individual components that either support or repress the production of mycotoxins in S. chartarum.}},
author = {{Ulrich, Sebastian and Schäfer, Cornelius}},
booktitle = {{Journal of Fungi}},
issn = {{2309-608X}},
keywords = {{Stachybotrys, genotype, macrocyclic trichothecenes, stachybotrylactam}},
number = {{3}},
publisher = {{MDPI }},
title = {{{Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media}}},
doi = {{10.3390/jof6030159}},
volume = {{6}},
year = {{2020}},
}
@misc{12962,
abstract = {{Background
Borrelia burgdorferi is a tick-borne spirochete that causes Lyme borreliosis (LB). After an initial tick bite, it spreads from the deposition site in the dermis to distant tissues of the host. It is generally believed that this spirochete disseminates via the hematogenous route. Borrelia persica causes relapsing fever and is able to replicate in the blood stream. Currently the exact dissemination pathway of LB pathogens in the host is not known and controversially discussed.
Methods
In this study, we established a strict intravenous infection murine model using host-adapted spirochetes. Survival capacity and infectivity of host-adapted B. burgdorferi sensu stricto (Bbss) were compared to those of B. persica (Bp) after either intradermal (ID) injection into the dorsal skin of immunocompetent mice or strict intravenous (IV) inoculation via the jugular vein. By in vitro culture and PCR, viable spirochetes and their DNA load in peripheral blood were periodically monitored during a 49/50-day course post-injection, as well as in various tissue samples collected at day 49/50. Specific antibodies in individual plasma/serum samples were detected with serological methods.
Results
Regardless of ID or IV injection, DNA of Bp was present in blood samples up to day 24 post-challenge, while no Bbss was detectable in the blood circulation during the complete observation period. In contrast to the brain tropism of Bp, Bbss spirochetes were found in ear, skin, joint, bladder, and heart tissue samples of only ID-inoculated mice. All tested tissues collected from IV-challenged mice were negative for traces of Bbss. ELISA testing of serum samples showed that Bp induced gradually increasing antibody levels after ID or IV inoculation, while Bbss did so only after ID injection but not after IV inoculation.
Conclusions
This study allows us to draw the following conclusions: (i) Bp survives in the blood and disseminates to the host’s brain via the hematogenous route; and (ii) Bbss, in contrast, is cleared rapidly from the blood stream and is a tissue-bound spirochete.}},
author = {{Liang, Liucun and Wang, Jinyong and Schorter, Lucas and Nguyen Trong, Thu Phong and Fell, Shari and Ulrich, Sebastian and Straubinger, Reinhard K.}},
booktitle = {{Parasites & vectors}},
issn = {{1756-3305}},
keywords = {{Lyme borreliosis, Borrelia burgdorferi, Tick-borne relapsing fever, Borrelia persica, Blood clearance}},
number = {{1}},
publisher = {{BioMed Central }},
title = {{{Rapid clearance of Borrelia burgdorferi from the blood circulation}}},
doi = {{10.1186/s13071-020-04060-y}},
volume = {{13}},
year = {{2020}},
}
@misc{12963,
abstract = {{The genus Borrelia comprises vector-borne bacterial pathogens that can severely affect human and animal health. Members of the Borrelia burgdorferi sensu lato species complex can cause Lyme borreliosis, one of the most common vector-borne diseases in the Northern hemisphere. Besides, members of the relapsing fever group of spirochetes can cause tick-borne relapsing fever in humans and various febrile illnesses in animals in tropical, subtropical and temperate regions. Borrelia spp. organisms are fastidious to cultivate and to maintain in vitro, and therefore, difficult to work with in the laboratory. Currently, borrelia identification is mainly performed using PCR and DNA sequencing methods, which can be complicated/frustrating on complex DNA templates and may still be relatively expensive. Alternative techniques such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) are not well established for Borrelia spp., although this technique is currently one of the most used techniques for rapid identification of bacteria in microbiological diagnostic laboratories. This is mainly due to unsatisfactory results obtained by use of simple sample preparation techniques and medium-contamination obscuring the mass spectra. In addition, comprehensive libraries for Borrelia spp. MALDI-TOF MS have yet to be established. In this study, we developed a new filter-based chemical extraction technique that allows measurement of high quality Borrelia spp. spectra from less than 100,000 bacteria per spot in MALDI-TOF MS. We used 49 isolates of 13 different species to produce the largest mass-library for Borrelia spp. so far and to validate the protocol. The library was successfully established and identifies >96% of used isolates correctly to species level. Cluster analysis on the sum spectra was applied to all the different isolates, which resulted in tight cluster generation for most species. Comparative analysis of the generated cluster to a phylogeny based on concatenated multi-locus sequence typing genes provided a surprising homology. Our data demonstrate that the technique described here can be used for fast and reliable species and strain typing within the borrelia complex.}},
author = {{Neumann-Cip, Anna-Cathrine and Fingerle, Volker and Margos, Gabriele and Straubinger, Reinhard K. and Overzier, Evelyn and Ulrich, Sebastian and Wieser, Andreas}},
booktitle = {{Frontiers in Microbiology}},
issn = {{1664-302X}},
keywords = {{Borrelia burgdorferi sensu lato, MALDI-TOF MS, typing, sample preparation, MALDI-TOF MS library, strain typing, automatic identification}},
publisher = {{Frontiers Media SA}},
title = {{{A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation}}},
doi = {{10.3389/fmicb.2020.00690}},
volume = {{11}},
year = {{2020}},
}
@misc{12964,
abstract = {{Antibodies represent an important element in the adaptive immune response and a major tool to eliminate microbial pathogens. For many bacterial and viral infections, efficient vaccines exist, but not for fungal pathogens. For a long time, antibodies have been assumed to be of minor importance for a successful clearance of fungal infections; however this perception has been challenged by a large number of studies over the last three decades. In this review, we focus on the potential therapeutic and prophylactic use of monoclonal antibodies. Since systemic mycoses normally occur in severely immunocompromised patients, a passive immunization using monoclonal antibodies is a promising approach to directly attack the fungal pathogen and/or to activate and strengthen the residual antifungal immune response in these patients.}},
author = {{Ulrich, Sebastian and Ebel, Frank}},
booktitle = {{Journal of Fungi}},
issn = {{2309-608X}},
keywords = {{monoclonal antibodies, invasive fungal infections, therapy, prophylaxis, opsonization}},
number = {{1}},
publisher = {{MDPI }},
title = {{{Monoclonal Antibodies as Tools to Combat Fungal Infections}}},
doi = {{10.3390/jof6010022}},
volume = {{6}},
year = {{2020}},
}
@misc{7928,
author = {{Frahm, Björn}},
location = {{SeAMK, Seinäjoki, Finnland}},
title = {{{Scale-up of stirred vessels}}},
year = {{2019}},
}
@article{1721,
abstract = {{In this contribution, the effect of the presence of a presumed inert gas like N2 in the feed gas on the biological methanation of hydrogen and carbon dioxide with Methanothermobacter marburgensis was investigated. N2 can be found as a component besides CO2 in possible feed gases like mine gas, weak gas, or steel mill gas. To determine whether there is an effect on the biological methanation of CO2 and H2 from renewable sources or not, the process was investigated using feed gases containing CO2, H2, and N2 in different ratios, depending on the CO2 content. A possible effect can be a lowered conversion rate of CO2 and H2 to CH4. Feed gases containing up to 47N2 were investigated. The conversion of hydrogen and carbon dioxide was possible with a conversion rate of up to 91 but was limited by the amount of H2 when feeding a stoichiometric ratio of 4:1 and not by adding N2 to the feed gas.}},
author = {{Hoffarth, Marc Philippe and Broeker, Timo and Schneider, Jan}},
issn = {{2311-5637}},
journal = {{Fermentation}},
keywords = {{biological methanation, CSTR, Methanothermobacter marburgensis, methane, carbon dioxide, dinitrogen, hydrogen, power-to-gas}},
number = {{3}},
publisher = {{MDPI }},
title = {{{Effect of N2 on Biological Methanation in a Continuous Stirred-Tank Reactor with Methanothermobacter marburgensis}}},
doi = {{10.3390/fermentation5030056}},
volume = {{5}},
year = {{2019}},
}
@misc{2391,
author = {{Hernández Rodriguez, Tanja and Posch, Christoph and Schmutzhard, Julia and Stettner, Josef and Weihs, Claus and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{Biotechnology and Bioengineering}},
issn = {{1097-0290}},
number = {{11}},
pages = {{2944--2959}},
publisher = {{Wiley}},
title = {{{Predicting industrial‐scale cell culture seed trains–A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method}}},
doi = {{10.1002/bit.27125}},
volume = {{116}},
year = {{2019}},
}
@misc{2400,
author = {{Ifrim, George Adrian and Titica, Mariana and Deppe, Sahar and Frahm, Björn and Barbu, Marian and Caraman, Sergiu}},
booktitle = {{2019 23rd International Conference on System Theory, Control and Computing (ICSTCC)}},
isbn = {{9781728106991}},
issn = {{2372-1618}},
publisher = {{IEEE}},
title = {{{Multivariable control strategy for the photosynthetic cultures of microalgae}}},
doi = {{10.1109/icstcc.2019.8886109}},
year = {{2019}},
}
@inbook{2646,
author = {{Beneke, B. and Fechner, T. and Upmann, Matthias}},
booktitle = {{ Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{264--273}},
publisher = {{Behr´s}},
title = {{{Bewertung von Knochenpartikeln in Produkten}}},
year = {{2019}},
}
@inbook{2648,
author = {{Upmann, Matthias and Beneke, B.}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, N.}},
pages = {{216--218}},
publisher = {{Behr´s}},
title = {{{Zusammengefügte Produkte und Formfleisch}}},
year = {{2019}},
}
@inbook{2649,
author = {{Beneke, B. and Upmann, Matthias}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{213--216}},
publisher = {{Behr´s}},
title = {{{Kochpökelerzeugnisse}}},
year = {{2019}},
}
@inbook{2650,
author = {{Beneke, B. and Langen, M. and Schering, B. and Upmann, Matthias}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{218--221}},
publisher = {{Behr´s}},
title = {{{Meat in meat-Technologie}}},
year = {{2019}},
}
@inbook{2651,
author = {{Upmann, Matthias}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{150--157}},
publisher = {{Behr´s}},
title = {{{Verdickungs- und Geliermittel}}},
year = {{2019}},
}
@inbook{2652,
author = {{Grünewald, T. and Upmann, Matthias}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{179--185}},
publisher = {{Behr´s}},
title = {{{Pflanzliche Fasern}}},
year = {{2019}},
}
@inbook{2657,
author = {{Fechner, T. and Upmann, Matthias and Kneissler, A.}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{118--124}},
publisher = {{Behr´s}},
title = {{{Knochengewebe}}},
year = {{2019}},
}
@inbook{2658,
author = {{Beneke, B. and Kneissler, A. and Upmann, Matthias}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{92--97}},
publisher = {{Behr´s}},
title = {{{Niere}}},
year = {{2019}},
}
@inbook{2659,
author = {{Beneke, B. and Langen, M. and Upmann, Matthias}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
pages = {{36--48}},
publisher = {{Behr´s}},
title = {{{Destruktionsformen der Skelettmuskulatur (Zerstörungsformen, Brät, Mus-kelabrieb)}}},
year = {{2019}},
}
@article{2660,
author = {{Beneke, B. and Grünewald, T. and Seideneck, R. and Upmann, Matthias}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{76--86}},
title = {{{Proteinzusätze – histologisches Erscheinungsbild und rechtliche Aspekte}}},
volume = {{99}},
year = {{2019}},
}
@inproceedings{2662,
author = {{Upmann, Matthias}},
location = {{Hannover}},
title = {{{Histologische Untersuchung von Fleisch und Wurstwaren - Möglichkeiten und Grenzen}}},
year = {{2019}},
}
@article{2663,
author = {{Beneke, B. and Schwarzkopf, C. and Upmann, Matthias}},
journal = {{Fleischwirtschaft}},
number = {{7}},
pages = {{86--95}},
title = {{{Proteinhaltige Zusätze detektieren}}},
volume = {{99}},
year = {{2019}},
}
@article{2664,
author = {{Upmann, Matthias and Lautenschläger, Ralf}},
journal = {{Der Lebensmittelkontrolleur}},
pages = {{10--11}},
title = {{{LAFF e.V. – fördert Wissenserwerb und Wissenstransfer}}},
volume = {{3}},
year = {{2019}},
}
@article{2666,
author = {{Upmann, Matthias and Weyland, Gerd}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{42--45}},
title = {{{Was ist erlaubt, was verboten? 15. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - 1. Teil}}},
volume = {{99}},
year = {{2019}},
}
@article{2667,
author = {{Upmann, Matthias and Weyland, Gerd}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{60--62}},
title = {{{Was ist erlaubt, was verboten? 15. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - 2. Teil}}},
volume = {{99}},
year = {{2019}},
}
@inproceedings{2668,
author = {{Upmann, Matthias}},
location = {{Garmisch-Partenkirchen}},
title = {{{Separatorenfleisch oder nicht? Konzept zur Einordnung von Geflügelrohstoffen. }}},
year = {{2019}},
}
@misc{2956,
author = {{Möller, J. and Müller, J. and Hernández Rodriguez, Tanja and Kuchemüller, K. B. and Arndt, L. and Frahm, Björn and Eibl, R. and Eibl, D. and Pörtner, R.}},
location = {{Wädenswil, Switzerland}},
title = {{{Workflow for model-assisted design and scale-up of biopharmaceutical production processes}}},
year = {{2019}},
}
@misc{2957,
author = {{Möller, J. and Kuchemüller, K. B. and Moser, A. and Hass, V. C. and Hernández Rodriguez, Tanja and Deppe, S. and Frahm, Björn and Pörtner, R.}},
location = {{Florence, Italy}},
title = {{{Model-Assisted Design of Experiments}}},
year = {{2019}},
}
@misc{2958,
author = {{Ifrim, George Adrian and Titica, M. and Deppe, S. and Frahm, Björn and Barbu, M. and Caraman, S.}},
location = {{Sinaia, Romania}},
title = {{{Novel control strategy for microalgae in photobioreactor}}},
year = {{2019}},
}
@misc{3000,
author = {{Hernández Rodriguez, Tanja and Posch, C. and Schmutzhard, J. and Stettner, J. and Weihs, J. and Pörtner, R. and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating}}},
year = {{2019}},
}
@misc{3001,
author = {{Hernández Rodriguez, Tanja and Posch, C. and Schmutzhard, J. and Stettner, J. and Weihs, J. and Pörtner, R. and Frahm, Björn}},
location = {{Copenhagen, Denmark}},
title = {{{Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating}}},
year = {{2019}},
}
@misc{3002,
author = {{Möller, J. and Kuchemüller, K. B. and Hernández Rodriguez, Tanja and Deppe, S. and Ifrim, George Adrian and Moser, A. and Hass, V. C. and Frahm, Björn and Pörtner, R.}},
location = {{Hamburg, Germany}},
title = {{{Model-Assisted Design of Experiments – Software Toolbox}}},
year = {{2019}},
}
@misc{3003,
author = {{Deppe, S. and Hernández Rodriguez, Tanja and Gassenmeier, Veronika and Tölle, M. and Kuhfuß, F. and Möller, J. and Kuchemüller, K. B. and Pörtner, R. and Moser, A. and Hass, V. C. and Ifrim, George Adrian and Frahm, Björn}},
location = {{Hamburg, Germany}},
title = {{{Model-assisted Design of Experiments for algae cultivation}}},
year = {{2019}},
}
@misc{3004,
author = {{Ifrim, George Adrian and Deppe, S. and Hernández Rodriguez, Tanja and Gassenmeier, Veronika and Frahm, Björn}},
location = {{Hamburg, Germany}},
title = {{{Modeling of microalgae in an air-lift photobioreactor for biomass production}}},
year = {{2019}},
}
@misc{3005,
author = {{Hernández Rodriguez, Tanja and Posch, C. and Schmutzhard, J. and Stettner, J. and Weihs, J. and Pörtner, R. and Frahm, Björn}},
location = {{Hamburg, Germany}},
title = {{{Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating}}},
year = {{2019}},
}
@misc{3006,
author = {{Ifrim, George Adrian and Titica, M. and Deppe, S. and Frahm, Björn and Barbu, M. and Caraman, S.}},
location = {{Sinaia, Romania}},
title = {{{Multivariable control strategy for the photosynthetic cultures of microalgae}}},
year = {{2019}},
}
@inproceedings{6159,
author = {{Müller, Ulrich and Blome, André and Meyer, A.}},
location = {{Lemgo}},
title = {{{Von I4.0 zu LM4.0 – Vielfalt, Sinnhaftigkeit und Mitwirkung von LM-Technologen}}},
year = {{2019}},
}
@inbook{5430,
author = {{Upmann, Matthias and Beneke, B. and Fechner, T.}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
publisher = {{Behr´s}},
title = {{{Bewertung von Knochenpartikeln in Produkten}}},
year = {{2019}},
}
@inbook{5431,
author = {{Upmann, Matthias and Röser, Anja}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
publisher = {{Behr´s}},
title = {{{Kochpökelerzeugnisse}}},
year = {{2019}},
}
@inbook{5432,
author = {{Upmann, Matthias and Beneke, B.}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
publisher = {{Behr´s}},
title = {{{Gewürze und Kräuter}}},
year = {{2019}},
}
@inbook{5433,
author = {{Upmann, Matthias and Fechner, T. and Kneissler, A.}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
publisher = {{Behr´s}},
title = {{{Knochengewebe}}},
year = {{2019}},
}
@inbook{5434,
author = {{Upmann, Matthias and Beneke, B. and Hoffarth, Marc}},
booktitle = {{Lebensmittelhistologie}},
editor = {{Horn, D. and Langen, M.}},
publisher = {{Behr´s}},
title = {{{Destruktionsformen der Skelettmuskulatur (Zerstörungsformen, Brät, Muskelabrieb)}}},
year = {{2019}},
}
@article{5435,
abstract = {{Towards renewable energy systems, the coupling of multiple sectors is important and incorporates novel technologies where currently no models exist that correctly represent all transient effects. Therefore, we present a method that incorporates Hardware-in-the-Loop simulations where virtual components as models are coupled to real and experimental facilities in real time. By including experimental components, a higher validity can be obtained and the practical applicability of renewable energy scenario can be discussed more profoundly. In this paper, the considered energy system consists of an experimental biocatalytic methanation reactor, a real photovoltaic park, a regenerative fuel cell and short-term storage units to supply a residential district. A representative control sequence of the methanator is obtained by modeling the scenario as an optimal control problem. A first HIL simulation highlights that modifications of the instrumentation are required for a grid injection of the generated methane. The scientific approach can be applied to any energy system where some of the considered components are available as experimental or real facilities. Non-exisiting components are simply replaced by models. The presented approach helps to determine which parts or process parameters are crucial for the planed operation before the overall energy system is realized on a larger scale. (C) 2019 Elsevier Ltd. All rights reserved.}},
author = {{Griese, Martin and Hoffrath, Marc Philippe and Broeker, Timo and Schulte, Thomas and Schneider, Jan}},
issn = {{1873-6785}},
journal = {{Energy : the international journal}},
keywords = {{Biological methanation, Energy management, HIL simulation, Optimization, Scalable models}},
location = {{Guimaraes, PORTUGAL}},
pages = {{77 -- 90}},
publisher = {{Elsevier}},
title = {{{Hardware-in-the-Loop simulation of an optimized energy management incorporating an experimental biocatalytic methanation reactor}}},
doi = {{10.1016/j.energy.2019.05.092}},
volume = {{181}},
year = {{2019}},
}
@article{5436,
author = {{Schneider, Jan and Broeker, Timo and Hoffrath, M.}},
journal = {{IfGB-Forum Spirituosen und Brennerei }},
title = {{{Power-to-Gas und biokatalytische Methanisierung – eine Perspektive zu Nutzung von Gärungskohlensäure}}},
year = {{2019}},
}
@inproceedings{5437,
author = {{Schwarzer, Knut and Katsch, Linda and Weishaupt, Imke and Schneider, Jan}},
location = {{München}},
title = {{{Cyberphysisches System zur thermischen Entkeimung von Getränken}}},
year = {{2019}},
}
@inproceedings{5438,
author = {{Lautenschläger, Ralf and Hölscher, M.}},
location = {{Stuttgart}},
title = {{{Irisieren in Koch- und Rohpökelwaren – Entstehung und mögliche Inhibierung}}},
year = {{2019}},
}
@article{5439,
author = {{Lautenschläger, Ralf and Scheffer, Dominik}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{75 -- 78}},
title = {{{Vollautomatisierung und Vernetzung – Neu- und Weiterentwicklung von Klima- und Rauchanlagen vor dem Hintergrund der Digitalisierung}}},
volume = {{99}},
year = {{2019}},
}
@article{5440,
author = {{Meyer, Alexander and Blome, André and Müller, Ulrich}},
journal = {{Getreide Mehl und Brot }},
number = {{01}},
publisher = {{Verlag Moritz Schäfer}},
title = {{{Von Industrie 4.0 zu Lebensmittel 4.0 – Vielfalt, Sinnhaftigkeit und die Mitwirkung von Lebensmitteltechnologen}}},
year = {{2019}},
}
@inproceedings{5441,
author = {{Danneel, Hans-Jürgen}},
location = {{Bielefeld}},
title = {{{Gewinnung hochwertiger Proteinhydrolysate aus Nebenströmen der Pflanzenverarbeitung}}},
year = {{2019}},
}
@inproceedings{5444,
author = {{Conradi, Florian and Wefing, Patrick and Schneider, Jan}},
location = {{Antwerpen}},
title = {{{Near infrared spectroscopy and mashing – a promising approach for real time inline quality control?}}},
year = {{2019}},
}
@inproceedings{5445,
author = {{Wefing, Patrick and Conradi, Florian and Schneider, Jan}},
location = {{Antwerpen}},
title = {{{Laboratory plant for a Continuous Closed Loop controlled Mashing aided by digital technologies}}},
year = {{2019}},
}
@article{5446,
author = {{Wittland, Sebastian and Stake, Kirsten and Schattenberg, Britta and Rohrbeck, Hanna and Hermenau, Ute and Schneider, Jan}},
issn = {{1617-4518}},
journal = {{Ernährung im Fokus}},
number = {{4}},
pages = {{262--267}},
publisher = {{Bundesanstalt für Landwirtschaft und Ernährung (BLE) }},
title = {{{Neuartige Zucker - Kalorienreduktion in Lebensmitteln}}},
year = {{2019}},
}
@inproceedings{5457,
author = {{Schneider, Jan and Wefing, Patrick and Conradi, Florian}},
location = {{Rust}},
title = {{{ Industry 4.0 and Continuous Mashing. - Design of a „closed loop controlled mashing“ pilot plant }}},
year = {{2019}},
}
@inproceedings{5459,
author = {{Wefing, Patrick and Conradi, Florian and Schneider, Jan}},
location = {{Braunschweig}},
title = {{{Industrie 4.0 in der Lebensmittelindustrie – Entwicklung einer „Closed Loop Controlled“ Maischeanlage}}},
year = {{2019}},
}
@inproceedings{5461,
author = {{Schwarzer, Knut}},
title = {{{Das Wasser des Lebens - Whisky aus Lemgo}}},
year = {{2019}},
}
@inproceedings{5463,
author = {{Broeker, Timo}},
location = {{Detmold}},
title = {{{bioCO2nvert - using CO2 for renewable energy storage }}},
year = {{2019}},
}
@article{5464,
author = {{Zimmer, Manuel and Schneider, Jan}},
journal = {{Croatian Journal of Food Science and Technology}},
publisher = {{Faculty of Food Technology Osijek}},
title = {{{Near-infrared diffuse reflectance spectroscopy for discriminating fruit and vegetable products preserved in glass containers}}},
year = {{2019}},
}
@inproceedings{5465,
author = {{Schneider, Jan and Weishaupt, Imke and Schwarzer, Knut and Katsch, Linda}},
location = {{München}},
title = {{{Cyberphysisches System zur thermischen Entkeimung von Getränken}}},
year = {{2019}},
}
@inproceedings{5466,
author = {{Zimmer, Manuel and Conradi, Florian and Wefing, Patrick and Schneider, Jan}},
location = {{Antwerpen}},
title = {{{Non-invasive on-line monitoring of the secondary bottle fermentation process using near infrared spectroscopy}}},
year = {{2019}},
}
@inproceedings{5467,
author = {{Huchtmann, Julian and Rossmann, Sören and Kindsvater, Verena and Eckel, Viktor P. and Jakob, Frank and Schneider, Jan}},
location = {{Antwerpen}},
title = {{{Microbial exopolysaccharides as an alternative for declarable thickeners}}},
year = {{2019}},
}
@inproceedings{5468,
author = {{Zimmer, Manuel and Schneider, Jan}},
location = {{Sevilla}},
title = {{{Non-invasive diffuse reflectance near-infrared spectroscopy for on-line monitoring and characterisation of food and beverages in sealed glass containers}}},
year = {{2019}},
}
@inproceedings{5469,
author = {{Weishaupt, Imke and Zimmer, Manuel and Schneider, Jan}},
location = {{Sevilla}},
title = {{{Gentle Flash Pasteurization of Fruit Juices through Product Identification and Characterization using Near-Infrared Spectroscopy as Inline Analytical Method}}},
year = {{2019}},
}
@misc{5470,
author = {{Katsch, Linda and Schneider, Jan}},
location = {{Dresden}},
number = {{S1}},
pages = {{127}},
title = {{{Schonende Pasteurisation von Fruchtsäften: Nicht-Isotherme kinetische Untersuchung qualitätsbestimmender Inhaltsstoffe}}},
doi = {{ https://doi.org/10.1002/lemi.201951127}},
volume = {{73}},
year = {{2019}},
}
@inproceedings{5471,
author = {{Conradi, Florian and Wefing, Patrick and Zhang, Fan and Schneider, Jan}},
location = {{Dresden}},
number = {{S1}},
pages = {{S103--S103}},
publisher = {{WILEY‐VCH}},
title = {{{Echtzeitqualitätssicherung enzymkatalysierter technologischer Prozesse am Beispiel des Maischens im Rahmen der Bierherstellung}}},
doi = {{10.1002/lemi.201951103}},
volume = {{73}},
year = {{2019}},
}
@inproceedings{5472,
author = {{Broeker, Timo and Hoffrath, M. and Schneider, Jan}},
location = {{Berlin}},
title = {{{Power-to-Gas und biokatalytische Methanisierung – eine Perspektive zu Nutzung von Gärungskohlensäure}}},
year = {{2019}},
}
@inproceedings{5473,
author = {{Sürmeli, Baris Gün and Weishaupt, Imke and Schwarzer, Knut and Schneider, Jan}},
title = {{{Beverage Classification Using Linear Discriminant Analysis with Covariance Matrix Shrinkage}}},
year = {{2019}},
}
@inproceedings{5474,
author = {{Schneider, Jan and Regtmeier, J. and Conradi, Florian and Wefing, Patrick}},
location = {{Bielefeld}},
title = {{{Das Labor in der Leitung – Smarte Qualitätskontrolle von Lebensmitteln durch innovative Sensortechnik}}},
year = {{2019}},
}
@inproceedings{5475,
author = {{Schneider, Jan and Conradi, Florian and Wefing, Patrick and Weishaupt, Imke and Zimmer, Manuel and Schwarzer, Knut}},
location = {{Lemgo}},
title = {{{Muss man die Aufheizzonen einer KZE in die PE-Berechnung einbeziehen?}}},
year = {{2019}},
}
@inproceedings{5476,
author = {{Schneider, Jan and Zimmer, Manuel and Weishaupt, Imke and Schattenberg, Britta and Conradi, Florian and Schwarzer, Knut}},
location = {{Bielefeld}},
title = {{{Lebensmittelverschwendung – Welchen Beitrag kann die Digitalisierung leisten? }}},
year = {{2019}},
}
@misc{12965,
abstract = {{The Bacillus (B.) cereus group consists of nine recognized species which are present worldwide. B. cereus play an important role in food-borne diseases by producing different toxins. Yet, only a small percentage of B. cereus strains are able to produce the heat stable cereulide, the causative agent of emetic food poisoning. To minimize the entry of emetic B. cereus into the food chain, food business operators are dependent on efficient and reliable methods enabling the differentiation between emetic and non-emetic strains.
Currently, only time-consuming cell bioassays, molecular methods and tandem mass spectrometry are available for this purpose. Thus, the aim of the present study was to establish a fast and reliable method for the differentiation between emetic/non-emetic strains by MALDI-TOF MS. Selected strains/isolates of the B. cereus group as well as other Bacillus spp. (total n = 121) were cultured on sheep blood agar for 48 h before analysis.
Subsequently, the cultures were directly analyzed by MALDI-TOF MS without prior extraction steps. The samples were measured in the mass range of m/z 800–1800 Da. Using ClinProTools 3.0 statistical software and Flex analysis software (Bruker Daltonics GmbH, Bremen, Germany), a differentiation between emetic/non-emetic isolates was possible with a rate of correct identification of 99.1% by means of the evaluation of two specific biomarkers (m/z 1171 and 1187 Da).}},
author = {{Ulrich, Sebastian and Gottschalk, Christoph and Dietrich, Richard and Märtlbauer, Erwin and Gareis, Manfred}},
booktitle = {{Food Microbiology}},
issn = {{1095-9998}},
keywords = {{MALDI-TOF MS, Bacillus cereus, Cereulide, Food intoxication}},
pages = {{75--81}},
publisher = {{Academic Press }},
title = {{{Identification of cereulide producing Bacillus cereus by MALDI-TOF MS}}},
doi = {{10.1016/j.fm.2019.01.012}},
volume = {{82}},
year = {{2019}},
}
@misc{12966,
abstract = {{The fungus Stachybotrys (S.) chartarum was isolated from culinary herbs, damp building materials, and improperly stored animal forage. Two distinct chemotypes of the fungus were described that produced either high-cytotoxic macrocyclic trichothecenes (S type) or low-cytotoxic atranones (A type). Recently, two distinct gene clusters were described that were found to be necessary for the biosynthesis of either macrocyclic trichothecenes (21 SAT (Satratoxin) genes) or atranones (14 ATR (Atranone) genes). In the current study, PCR primers were designed to detect SAT and ATR genes in 19 S. chartarum chemotype S and eight S. chartarum chemotype A strains. Our analysis revealed the existence of three different genotypes: satratoxin-producing strains that harbored all SAT genes but lacked the ATR gene cluster (genotype S), non-satratoxin-producing strains that possessed the ATR genes but lacked SAT genes (genotype A), and a hitherto undescribed hybrid genotype among non-satratoxin-producing strains that harbored all ATR genes and an incomplete set of SAT genes (genotype H). In order to improve the discrimination of genotypes, a triplex PCR assay was developed and applied for the analysis of S. chartarum and S. chlorohalonata cultures. The results show that genes for macrocyclic trichothecenes and atranones are not mutually exclusive in S. chartarum. Correlation of the new genotype-based concept with mycotoxin production data shows also that macrocyclic trichothecenes are exclusively produced by S. chartarum genotype S strains.}},
author = {{Ulrich, Sebastian and Niessen, Ludwig and Ekruth, Julia and Schäfer, Cornelius and Kaltner, Florian and Gottschalk, Christoph}},
booktitle = {{Mycotoxin Research}},
issn = {{1867-1632}},
keywords = {{Acetyltransferases, Chlamydomonas reinhardtii, Fungal Genes, Fungal genetics, Fungal genomics, Saccharomyces cerevisiae}},
number = {{1}},
pages = {{83--91}},
publisher = {{Springer}},
title = {{{Truncated satratoxin gene clusters in selected isolates of the atranone chemotype of Stachybotrys chartarum (Ehrenb.) S. Hughes}}},
doi = {{10.1007/s12550-019-00371-x}},
volume = {{36}},
year = {{2019}},
}
@misc{12967,
abstract = {{Objectives
To evaluate matrix-assisted laser desorption ionisation time of flight mass spectrometry (MALDI-TOF MS) combined with the Sepsityper kit (Bruker Daltoniks GmbH, Bremen) for the direct detection of bacterial species from inoculated blood cultures from dogs and cats.
Materials and Methods
Canine and feline blood samples were inoculated with typical sepsis-causing bacteria such as Staphylococcus intermedius, Staphylococcus aureus, Streptococcus canis, Enterococcus faecalis, Escherichia coli and Pseudomonas aeruginosa at two distinct concentrations (each in triplicate), resulting in 72 blood culture bottles incubated at 37°C. Samples were comparatively analysed with MALDI-TOF MS after preparation with the Sepsityper kit and also by standard bacteriology (culturing and biochemical characterisation).
Results
Bacterial species identified from agar plates and by MALDI-TOF MS from blood culture bottles were identical for all samples. The MALDI Biotyper software (Bruker Daltoniks) correctly identified all bacterial strains from inoculated canine and feline blood with analysis indicating very good precision.
Clinical Significance
MALDI-TOF MS analysis combined with the Sepsityper kit is a reliable tool for a quick detection of veterinary-relevant bacterial species directly from blood culture bottles. This approach could reduce the time for identification of critical species to only 24 hours.}},
author = {{Ulrich, Sebastian and Gottschalk, C. and Straubinger, R. Kk and Schwaiger, K. and Dörfelt, R.}},
booktitle = {{Journal of Small Animal Practice}},
issn = {{0022-4510}},
number = {{1}},
pages = {{42--45}},
publisher = {{Wiley-Blackwell}},
title = {{{Acceleration of the identification of sepsis‐inducing bacteria in cultures of dog and cat blood}}},
doi = {{10.1111/jsap.13056}},
volume = {{61}},
year = {{2019}},
}
@misc{12971,
abstract = {{The genus Stachybotrys produces a broad diversity of secondary metabolites, including macrocyclic trichothecenes, atranones, and phenylspirodrimanes. Although the class of the phenylspirodrimanes is the major one and consists of a multitude of metabolites bearing various structural modifications, few investigations have been carried out. Thus, the presented study deals with the quantitative determination of several secondary metabolites produced by distinct Stachybotrys species for comparison of their metabolite profiles. For that purpose, 15 of the primarily produced secondary metabolites were isolated from fungal cultures and structurally characterized in order to be used as analytical standards for the development of an LC-MS/MS multimethod. The developed method was applied to the analysis of micro-scale extracts from 5 different Stachybotrys strains, which were cultured on different media. In that process, spontaneous dialdehyde/lactone isomerization was observed for some of the isolated secondary metabolites, and novel stachybotrychromenes were quantitatively investigated for the first time. The metabolite profiles of Stachybotrys species are considerably influenced by time of growth and substrate availability, as well as the individual biosynthetic potential of the respective species. Regarding the reported adverse effects associated with Stachybotrys growth in building environments, combinatory effects of the investigated secondary metabolites should be addressed and the role of the phenylspirodrimanes re-evaluated in future research.}},
author = {{Jagels, Annika and Lindemann, Viktoria and Ulrich, Sebastian and Gottschalk, Christoph and Cramer, Benedikt and Hübner, Florian and Gareis, Manfred and Humpf, Hans-Ulrich}},
booktitle = {{Toxins}},
issn = {{2072-6651}},
keywords = {{Stachybotrys spp., metabolite profiles, LC-MS/MS, satratoxins, phenylspirodrimanes, stachybotrychromenes, biosynthetic production}},
number = {{3}},
publisher = {{MDPI}},
title = {{{Exploring Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS}}},
doi = {{10.3390/toxins11030133}},
volume = {{11}},
year = {{2019}},
}
@misc{7935,
author = {{Hernández Rodriguez, Tanja and Frahm, Björn and Posch, Christoph and Schmutzhard, Julia and Stettner, Josef}},
location = {{Kundl, Austria}},
title = {{{A model-assisted approach for design, optimization and control of bioprocesses – a software tool for seed train simulation and optimization}}},
year = {{2018}},
}
@inproceedings{2011,
author = {{Lohweg, Volker and Funk, Mark and Scharf, Matthias and Dörksen, Helene and Danneel, Hans-Jürgen and Hübner, Michael and Schaede, Johannes and Thony, Emmanuel and Knobloch, Alexander and Lee, Dinh Khoi and Mönks, Uwe and Gillich, Eugen}},
booktitle = {{Optical Document Security - The Conference on Optical Security and Counterfeit Detection XII San Francisco}},
location = {{San Francisco, USA}},
title = {{{smartBN—Intelligent Protection and Authentication in Payment Transactions by Smart Banknotes}}},
year = {{2018}},
}
@misc{2390,
author = {{Möller, J. and Kuchemüller, K. B. and Hernández Rodriguez, Tanja and Frahm, Björn and Hass, V. C. and Pörtner, R. }},
booktitle = {{American Pharmaceutical Review}},
issn = {{1099-8012}},
pages = {{39--41}},
publisher = {{Russel}},
title = {{{Model-Assisted Design of Process Strategies for Cell Culture Processes}}},
volume = {{3}},
year = {{2018}},
}
@inproceedings{2639,
author = {{Upmann, Matthias}},
location = {{Fulda}},
title = {{{Das Schwein als Lebensmittel}}},
year = {{2018}},
}
@inproceedings{2640,
author = {{Upmann, Matthias and Lautenschläger, Ralf}},
location = {{Soest}},
title = {{{Kochpökelwaren und Salami aus dem Fleisch vom Bruderhahn}}},
year = {{2018}},
}
@inproceedings{2641,
author = {{Fechner, T. and Röser, Anja and Upmann, Matthias}},
location = {{Garmisch-Partenkirchen }},
title = {{{Stolpersteine beim histologischen Knochenpartikelnachweis}}},
year = {{2018}},
}
@inproceedings{2642,
author = {{Upmann, Matthias and Tobey, A.}},
location = {{Garmisch-Partenkirchen}},
title = {{{Verarbeitungsfleisch vom Putenhals - geeignet für Produkte der Spitzenqualität?}}},
year = {{2018}},
}
@article{2643,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{52--54}},
title = {{{Was ist erlaubt, was verboten? 14. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - 1. Teil}}},
volume = {{98}},
year = {{2018}},
}
@article{2644,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{57--58}},
title = {{{Was ist erlaubt, was verboten? 14. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - 2. Teil}}},
volume = {{98}},
year = {{2018}},
}
@article{2645,
author = {{Weyland, Gerd and Upmann, Matthias}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{64--68}},
title = {{{Was ist erlaubt, was verboten? 14. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - 3. Teil}}},
volume = {{98}},
year = {{2018}},
}
@misc{2821,
author = {{Hernández Rodriguez, Tanja and Krull, Susan and Hass, Volker C. and Möller, Johannes and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{BMC Proceedings}},
issn = {{1753-6561}},
location = {{Lausanne, Switzerland}},
pages = {{P175}},
publisher = {{BioMed Central}},
title = {{{Model-assisted cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization}}},
doi = {{10.1186/s12919-018-0097-x}},
volume = {{112}},
year = {{2018}},
}
@inproceedings{2879,
author = {{Kutz, Gerd and Repka, M. and Thipsay, P.}},
location = {{Granada (Spanien)}},
title = {{{Impact of formulation and process parameters in twin screw hot-melt granulation coupled with in-line particle size analysis of sustained release HPMC granules}}},
year = {{2018}},
}
@inproceedings{2881,
author = {{Kutz, Gerd and Daniels, R. and Kamke, Dominic}},
location = {{Granada (Spanien)}},
title = {{{Real time control of melt granulation processes by inline measurement of particle size}}},
year = {{2018}},
}
@inproceedings{2883,
author = {{Kutz, Gerd and Schlebach, Simon and Kamke, Dominic}},
location = {{Granada (Spanien)}},
title = {{{Fluid bed drying – Characterization by DoE}}},
year = {{2018}},
}
@misc{2955,
author = {{Pörtner, R. and Möller, J. and Frahm, Björn and Hass, V. C.}},
location = {{Lisbon, Portugal}},
title = {{{Model-Assisted Design of Process Strategies for Cell Culture Processes}}},
year = {{2018}},
}
@misc{2997,
author = {{Möller, J. and Kuchemüller, K. B. and Freiberger, F. and Levermann, P. and Hernández Rodriguez, Tanja and Frahm, Björn and Hass, V. C. and Pörtner, R.}},
location = {{Recklinghausen, Germany}},
title = {{{Model-Assisted Design and Optimization of Process Strategies}}},
year = {{2018}},
}
@misc{2999,
author = {{Hernández Rodriguez, Tanja and Möller, J. and Kuchemüller, K. B. and Freiberger, F. and Levermann, P. and Hass, V. C. and Frahm, Björn and Pörtner, R.}},
location = {{Berlin, Germany}},
title = {{{Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses}}},
year = {{2018}},
}
@inproceedings{5630,
author = {{Conradi, F. P. and Wefing, Patrick and Pinkal, K. and Zhang, Fan and Niggemann, Oliver and Schneider, Jan}},
location = {{Gent}},
title = {{{Inline progress measurement of the ß-amylase rest in the mashing process employing a near infrared transflectance probe}}},
year = {{2018}},
}
@inproceedings{5631,
author = {{Wefing, Patrick and Conradi, F. P. and Fuchs, Lara and Schoppmeier, J. W. and Pinkal, K. and Niggemann, Oliver and Schneider, Jan}},
location = {{Gent}},
title = {{{Laboratory plant for a closed loop-controlled continuous (CLCC) mashing}}},
year = {{2018}},
}
@article{5632,
author = {{Broeker, Timo and Schneider, Jan}},
journal = {{Brauwelt }},
number = {{19}},
pages = {{530 --532}},
publisher = {{Carl Hanser Verlag}},
title = {{{Oxidativer Aufschluss von Biertreber}}},
volume = {{2018}},
year = {{2018}},
}
@inproceedings{5633,
author = {{Conradi, F. P. and Wefing, Patrick and Pinkal, K. and Zhang, Fan and Niggemann, Oliver and Schneider, Jan}},
location = {{Berlin}},
title = {{{Inline progress measurement of the ß-amylase rest in the mashing process employing a near infrared transflectance probe}}},
year = {{2018}},
}
@inproceedings{5634,
author = {{Wefing, Patrick and Conradi, Florian}},
location = {{Berlin}},
title = {{{Industrie 4.0 und Maischen – Aufbau einer Pilotanlage zum closed loop controlled mashing}}},
year = {{2018}},
}
@inproceedings{5635,
author = {{Zimmer, Manuel and Schneider, Jan}},
title = {{{Near-infrared spectroscopy on food in glass containers - discrimination studies in the context of Industry 4.0}}},
year = {{2018}},
}
@inproceedings{5636,
author = {{Broeker, Timo}},
location = {{Essen}},
title = {{{Implementierung eines bedarfsgerechten Power-to-Gas-Konzeptes in CO2 emittierende Fermentationsanlagen}}},
year = {{2018}},
}
@article{5637,
author = {{Zimmer, Manuel and Schneider, Jan}},
journal = {{FoodLab}},
number = {{4}},
title = {{{Nahinfrarot-Spektroskopie - Schlüsseltechnologie für die Pasteurisation im Zeitalter von Industrie 4.0}}},
volume = {{2018}},
year = {{2018}},
}
@inproceedings{5638,
author = {{Huchtmann, Julian and Rossmann, Sören and Kindsvater, Verena and Eckel, V. and Jakob, F. and Schneider, Jan}},
location = {{Bremerhafen}},
title = {{{Microbial exopolysaccharides as an alternative for declarable thickeners}}},
year = {{2018}},
}
@inproceedings{5639,
author = {{Schwarzer, Knut and Dammann_, Anna and Schneider, Jan}},
location = {{Bremerhafen}},
title = {{{Der Tod in der Aufheizzone - Welchen Anteil haben die Temperierzonen an der Gesamthitzeeinwirkung in einer KZE ? }}},
year = {{2018}},
}
@inproceedings{5640,
author = {{Schwarzer, Knut and Wilhelm, Patrick and Schneider, Jan and Müller, Ulrich}},
isbn = {{978-83-951359-0-3 }},
location = {{Wroclaw/Poland}},
publisher = {{Uniwersytet Przyrodniczy}},
title = {{{The Lemgo D- and z value Database for Food – An Instrument for the Dimensioning Pasteurization Process}}},
year = {{2018}},
}
@inproceedings{5641,
author = {{Müller, Ulrich and Rossmann, Sören and Merck, C. and Schneider, Jan}},
location = {{Kigali/ Rwanda}},
title = {{{DIRECT HOMOGENIZATION OF BEVERAGE EMULSIONS WITH THE INNOVATIVE COUNTERFLOW INJECTION PROCESS}}},
year = {{2018}},
}
@inproceedings{5642,
author = {{Wefing, Patrick and Conradi, F. P.}},
location = {{Berlin}},
title = {{{Industrie 4.0 und Maischen – Aufbau einer Pilotanlage zum closed loop controlled mashing}}},
year = {{2018}},
}
@inproceedings{5643,
author = {{Zimmer, Manuel and Schneider, Jan}},
title = {{{Near-infrared spectroscopy o n food in glass containers - discrimination studies in the context of Industry 4.0}}},
year = {{2018}},
}
@inproceedings{5644,
author = {{Broeker, Timo}},
location = {{Essen}},
title = {{{Implementierung eines bedarfsgerechten Power-to-Gas-Konzeptes in CO2 emittierende Fermentationsanlagen}}},
year = {{2018}},
}
@inproceedings{5645,
author = {{Rossmann, Sören and Schneider, Jan and Müller, Ulrich}},
location = {{Wroclaw/Poland}},
title = {{{Direct homogenization of beverage emulsions with the innovative counterflow injection (CFI) process}}},
year = {{2018}},
}
@inproceedings{5646,
author = {{Huchtmann, Julian and Rossmann, Sören and Kindsvater, Verena and Eckel, V. P. L. and Jakob, F. and Schneider, Jan}},
location = {{Wroclaw/Poland}},
title = {{{Microbial exopolysaccharides as an alternative for declarable thickeners}}},
year = {{2018}},
}
@article{5649,
author = {{Lautenschläger, Ralf}},
issn = {{ 0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{7}},
pages = {{44 -- 47}},
title = {{{Die optimale Kombination macht‘s}}},
volume = {{98}},
year = {{2018}},
}
@article{5650,
author = {{Lautenschläger, Ralf and Thumel, Heinrich and Bleile, B.}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{64 -- 68}},
title = {{{Bandbreite im Geschmack fehlt – DLG-Qualitätsprüfung 2018 – Rohwürste und Rohpökelwaren}}},
volume = {{98}},
year = {{2018}},
}
@article{5651,
author = {{Lautenschläger, Ralf}},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{98 -- 106}},
title = {{{Behandlung von Fleischerzeugnissen und Fleisch mit hohem hydrostatischen Druck – Aspekte der Anwendung und der Auswirkungen dieses Verfahrens auf die Produkteigenschaften}}},
volume = {{98}},
year = {{2018}},
}
@inproceedings{5652,
author = {{Danneel, Hans-Jürgen}},
title = {{{Neue Technologien zur Veredlung pflanzlicher Proteine-auch für Nicht-Vegetarier eine Alternative?}}},
year = {{2018}},
}
@article{5653,
author = {{Seidel, Leopold and Zapp, Jürgen and Kothe, Achim}},
journal = {{Lebensmittelchemie}},
pages = {{125}},
title = {{{Untersuchung von Wildäpfeln aus Kasachstan auf Polyphenole und deren antioxidative Kapazität}}},
volume = {{72}},
year = {{2018}},
}
@inproceedings{5654,
author = {{Seidel, Leopold and Zapp, Jürgen}},
location = {{Bremerhaven}},
title = {{{Einsatz von pflanzlichen Extrakten zur Vermeidung von Lipidoxidation}}},
year = {{2018}},
}
@inproceedings{5655,
author = {{Zapp, Jürgen}},
location = {{ Grünbach, Österreich }},
title = {{{Streuobstsorten für Allergiker}}},
year = {{2018}},
}
@inproceedings{5658,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
location = {{Berlin}},
title = {{{Untersuchung zum Einfluss der Partikelgrößenänderung während der dynamischen }}},
year = {{2018}},
}
@inproceedings{5659,
author = {{Pröpper, Marvin and Rossmann, Sören and Müller, Ulrich}},
location = {{Berlin}},
title = {{{Beitrag zur Aufklärung der Homogenisierung von Getränkeemulsionen mittels Gegenstrominjektion durch dynamische Grenzflächenspannungsmessungen}}},
year = {{2018}},
}
@inproceedings{5660,
author = {{Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Gegenstrominjektion - eine Möglichkeit der Herstellung verschiedener Verbrauchsgüteremulsionen (Counter Flow Injection - a Tool to produce different Consumer Product Emulsions) Sepawa}}},
year = {{2018}},
}
@inproceedings{5661,
author = {{Müller, Ulrich}},
location = {{Science Center, Köln}},
title = {{{Gegenstrominjektion - eine Möglichkeit der Herstellung verschiedener Verbrauchsgüteremulsionen (Counter Flow Injection - a Tool to produce different Consumer Product Emulsions) Sepawa}}},
year = {{2018}},
}
@inproceedings{5662,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
location = {{Wroclaw/Poland}},
title = {{{Mechanical Steam Treatment (MSD) of plant material“}}},
year = {{2018}},
}
@inproceedings{5663,
author = {{Schwarzer, Knut and Wilhelm, Patrick and Schneider, Jan and Müller, Ulrich}},
location = {{Wroclaw/Poland}},
title = {{{The Lemgo D- and z-value database for food – an instrument fort he dimensioning of pasteurization process, poster presentation}}},
year = {{2018}},
}
@inproceedings{5664,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
location = {{ Wroclaw/Poland}},
title = {{{Comparision oft he static and dyynamic freeze-drying by means of modelling}}},
year = {{2018}},
}
@article{5665,
author = {{Müller, Ulrich and Pliske, Roland and Kohlus, R.}},
journal = {{Chemie-Ingenieur-Technik}},
number = {{8}},
pages = {{1097 -- 1103}},
title = {{{Modellierung der Trocknungsdauer für die dynamische Gefriertrocknung (Modeling drying time of dynamic freeze drying)}}},
volume = {{90}},
year = {{2018}},
}
@inproceedings{5666,
author = {{Meyer, Alexander and Blome, André and Müller, Ulrich}},
editor = {{Meyer, Alexander}},
location = {{Bremerhaven}},
title = {{{Von Industrie 4.0 zu Lebensmittel 4.0 und der Einfluss der Lebensmitteltechnologie}}},
year = {{2018}},
}
@inproceedings{5667,
author = {{Conreder, Andi Virachai and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Bremerhaven}},
title = {{{Beitrag zur Aufklärung der Funktionsweise der Gegenstrominjektion, einer direkten Homogenisationsmethode zur Herstellung stabiler Emulsionen}}},
year = {{2018}},
}
@inproceedings{5668,
author = {{Müller, Ulrich and Pliske, Roland and Kohlus, R.}},
location = {{Bremerhaven}},
title = {{{R. Prinzip und Vorteile einer dynamischen Starterkulturgefriertrocknung gegenüber der statischen Gefriertrocknung}}},
year = {{2018}},
}
@inproceedings{5669,
author = {{Müller, Ulrich and Sinz, Lenard Jonas and Pliske, Roland}},
location = {{Bremerhaven}},
title = {{{Bestimmung von Wärmleitfähigkeiten sublimierender Starterkulturpellets zur wärmeflussbilanzierten Modellierung der statischen Gefriertrocknung}}},
year = {{2018}},
}
@inproceedings{5670,
author = {{Blome, André and Meyer, Alexander and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Von I4.0 zu LM4.0 – Vielfalt, Sinnhaftigkeit und Mitwirkung von LM-Technologen) }}},
year = {{2018}},
}
@inproceedings{6155,
author = {{Schwarzer, Knut and Wilhelm, Patrick and Schneider, Jan and Müller, Ulrich}},
booktitle = {{Proceedings of the 8th International Conference on the Quality and Safety in Food Production Chain}},
isbn = {{9788395135903}},
location = {{Wroclaw/Poland}},
publisher = {{Uniwersytet Przyrodniczy. Wydział Biotechnologii i Nauk o Żywności}},
title = {{{The Lemgo D- and z-value database for food – an instrument for the dimensioning of pasteurization process}}},
year = {{2018}},
}
@inproceedings{6160,
author = {{Blome, André and Meyer, A. and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Von I4.0 zu LM4.0 – Vielfalt, Sinnhaftigkeit und Mitwirkung von LM-Technologen}}},
year = {{2018}},
}
@inproceedings{6162,
author = {{Müller, Ulrich and Sinz, Lenard Jonas and Pliske, Roland}},
location = {{Bremerhaven}},
title = {{{Bestimmung von Wärmleitfähigkeiten sublimierender Starterkultur-pellets zur wärmeflussbilanzierten Modellierung der statischen Gefriertrocknung}}},
year = {{2018}},
}
@inproceedings{6185,
author = {{Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Gegenstrominjektion - eine Möglichkeit der Herstellung verschiedener Verbrauchsgüteremulsionen (Counter Flow Injection - a Tool to produce different Consumer Product Emulsions)}}},
year = {{2018}},
}
@inproceedings{6186,
author = {{Müller, Ulrich}},
location = {{Science Center, Köln}},
title = {{{Gegenstrominjektion - eine Möglichkeit der Herstellung verschiedener Verbrauchsgüteremulsionen (Counter Flow Injection - a Tool to produce different Consumer Product Emulsions)}}},
year = {{2018}},
}
@inproceedings{6187,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
isbn = {{9788395135903 }},
location = {{Wroclaw/Poland}},
publisher = {{Uniwersytet Przyrodniczy. Wydział Biotechnologii i Nauk o Żywności}},
title = {{{Mechanical Steam Treatment (MSD) of plant material}}},
year = {{2018}},
}
@inproceedings{6188,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
location = {{Wroclaw/Poland}},
title = {{{Comparision of the static and dyynamic freeze-drying by means of modelling}}},
year = {{2018}},
}
@misc{12973,
abstract = {{Psychrophilic and psychrotolerant clostridia (n = 110) were isolated from vacuum-packed meat (beef and lamb), fresh venison and from skin and fecal samples of wild boars. They were identified to species level using MALDI-TOF MS, sequence and phylogeny analysis of the 16S rRNA and species specific multiplex qPCR. The results of all three methods were concordant. The majority of isolates were identified as C. tagluense-like Group I (n = 34) and Group II (n = 42). Thirty-five isolates could be identified to species level as follows: C. estertheticum (n = 15), C. frigoriphilum (n = 13), C. frigidicarnis (n = 1) and C. bowmanii (n = 5). This is the first report of detection and identification of C. frigoriphilum and C. tagluense-like Group II as causative agents of blown pack spoilage of beef. The species specific multiplex qPCR developed in this study could be applied to identify and to quantify the Clostridium species described above in suspicious meat juice samples.}},
author = {{Dorn-In, Samart and Schwaiger, Karin and Springer, Claudia and Barta, Leonard and Ulrich, Sebastian and Gareis, Manfred}},
booktitle = {{International Journal of Food Microbiology}},
issn = {{1879-3460}},
keywords = {{Blown pack spoilage, MALDI-TOF MS, PCR, 16S rRNA, C. frigoriphilum, C. tagluense-like}},
pages = {{162--169}},
publisher = {{Elsevier }},
title = {{{Development of a multiplex qPCR for the species identification of Clostridium estertheticum, C. frigoriphilum, C. bowmanii and C. tagluense-like from blown pack spoilage (BPS) meats and from wild boars}}},
doi = {{10.1016/j.ijfoodmicro.2018.08.020}},
volume = {{286}},
year = {{2018}},
}
@misc{12974,
abstract = {{BACKGROUND
Fruits and vegetables have increasingly been related to foodborne outbreaks. Besides surface contamination, a possible internalization of microorganisms into edible parts of plants during growth has already been observed. To examine an actual risk for the consumer, microbial contamination of the rind and pulp of 147 muskmelons from international trade was assessed using cultural and biochemical methods, polymerase chain reaction and matrix-assisted laser desorption/ionization-time of flight mass spectrometry.
RESULTS
One hundred percent of the rind samples [3.69–8.92 log colony forming units (CFU) g−1] and 89.8% of the pulp samples (maximum load 3.66 log CFU g−1) were microbiologically contaminated. Among the 432 pulp isolates, opportunistic and potentially pathogenic bacteria were identified, mainly Staphylococcus spp. (48.9%), Clostridium spp. (42.9%) and Enterobacteriaceae (27.9%). Salmonella spp., Escherichia coli and isolates of the Bacillus cereus group were found on the rind (1.4%, 0.7% and 42.9%, respectively) and in the pulp (0.7%, 1.4% and 4.7%). Clostridium perfringens was isolated from the rind of seven melons.
CONCLUSION
The present study revealed a regularly occurring internal contamination of melons. Possible health risks for consumers because of an occurrence of microorganisms in melon pulp should be considered in future food safety assessments. © 2018 Society of Chemical Industry.}},
author = {{Esteban‐Cuesta, Irene and Drees, Nathalie and Ulrich, Sebastian and Stauch, Peter and Sperner, Brigitte and Schwaiger, Karin and Gareis, Manfred and Gottschalk, Christoph}},
booktitle = {{Journal of the science of food and agriculture : incorporating Agri-Biotech}},
issn = {{1097-0010}},
keywords = {{foodborne pathogens, Salmonella, Listeria monocytogenes, Enterobacteriaceae, vegetables}},
number = {{13}},
pages = {{5074--5081}},
publisher = {{Wiley}},
title = {{{Endogenous microbial contamination of melons (Cucumis melo) from international trade: an underestimated risk for the consumer?}}},
doi = {{10.1002/jsfa.9045}},
volume = {{98}},
year = {{2018}},
}
@misc{12988,
abstract = {{BACKGROUND
Bacterial contamination of platelet concentrates (PCs) is still a major challenge in transfusion medicine. Different methodologic concepts and screening strategies have been developed and investigated concerning their usability. We evaluated the feasibility of BacT/ALERT automated culture (BacT/A, bioMérieux) with late sampling after 3 days at the earliest.
STUDY DESIGN AND METHODS
Twenty-four bacterial strains isolated from PCs and six relevant strains from reference stocks were spiked into apheresis-derived PCs (10-60 colony-forming units [CFU]/bag). Sampling was performed after 3 days, and bacterial detection was investigated using the two detection methods (BacT/A and BactiFlow [BF], bioMérieux). The maximum time-to-result of BacT/A was set to less than 12 hours.
RESULTS
All medium- or high-pathogenic strains are capable of proliferating to high titers, and 100% of contaminated samples were detected by BF and BacT/A (6 to ≤12 h incubation); lower detection rates of BacT/A were obtained within 6 hours of incubation (≤6 h: 76.2-93.4%). The majority of low-pathogenic isolates are also capable of growing in PCs (89.7%), showing a detection rate of 74.3% for BF versus 54.3% for BacT/A (6 to ≤12 h incubation). BacT/A failed to detect bacteria within 6 hours of incubation. Certainly, a small number of strains did not grow under PC storage conditions and were detectable by BacT/A only with increased detection times.
CONCLUSIONS
Late sampling after 3 days at the earliest, combined with reduced BacT/A incubation following the negative-to-date concept, offer an alternative opportunity to extend the shelf life of PCs from 4 to 5 days in Germany. The sensitivity of BacT/A with late sampling is nearly comparable to BF; the time-to-result is considerably longer.
}},
author = {{Vollmer, Tanja and Dabisch-Ruthe, Mareike and Weinstock, Melanie and Knabbe, Cornelius and Dreier, Jens}},
booktitle = {{Transfusion}},
issn = {{1537-2995}},
number = {{7}},
pages = {{1654--1664}},
publisher = {{Wiley-Blackwell}},
title = {{{Late sampling for automated culture to extend the platelet shelf life to 5 days in Germany}}},
doi = {{10.1111/trf.14617}},
volume = {{58}},
year = {{2018}},
}
@misc{12989,
author = {{Dabisch-Ruthe, Mareike and Weinstock, Melanie and Pfannebecker, Jens and Becker, Barbara}},
booktitle = {{26th International ICFMH Conference - FoodMicro 2018}},
location = {{Berlin}},
pages = {{482}},
title = {{{Usage of cold hydrogen peroxide vapour for inactivation of murine norovirus on fruit and vegetable surfaces.}}},
doi = {{10.13140/RG.2.2.12883.08484}},
year = {{2018}},
}
@misc{12990,
author = {{Dabisch-Ruthe, Mareike and Weinstock, Melanie and Pfannebecker, Jens and Meyer, Sonja and Schwetka, Mona and Becker, Barbara}},
booktitle = {{70th Annual Conference of the German Society of Hygiene and Microbiology}},
isbn = {{978-3-9816508-6-0}},
location = {{Bochum}},
publisher = {{Conventus Congressmanagement & Marketing GmbH }},
title = {{{Application of cold nebulized hydrogen peroxide for inactivation of murine norovirus, bacteria and bacteria spores on surfaces in food production.}}},
doi = {{10.13140/RG.2.2.22949.41447}},
year = {{2018}},
}
@misc{12139,
author = {{Daniels, R. and Kamke, Dominic and Kutz, Gerd}},
location = {{San Diego (USA)}},
title = {{{An Innovative Tool For Real-Time Particle Size Measurement During High-Shear Melt Granulation}}},
year = {{2017}},
}
@misc{12140,
author = {{Thipsay, P. and Bookwala, M. and Kutz, Gerd and Repka, M. and Ye, X.}},
location = {{San Diego (USA).}},
title = {{{Effect of Different HPMC Grades and Process Parameters on Physic-Chemical Properties of Sustained Release Matrix Granules Prepared via Twin Screw Melt Granulation}}},
year = {{2017}},
}
@misc{12141,
author = {{Thipsay, P. and Kutz, Gerd and Repka, M.}},
location = {{San Diego (USA)}},
title = {{{In-Line Particle Size Analysis of Sustained Release HPMC Matrix Granules to Study the Impact of Formulation and Process Parameters in Twin Screw Hot-Melt Granulation}}},
year = {{2017}},
}
@misc{12142,
author = {{Vo, A. and Kamke, Dominic and Kim, D. and Martin, S. and Repka, M. and Kutz, Gerd}},
location = {{San Diego (USA)}},
title = {{{Inline Particle Size Analysis to Monitor in Real Time Continuous Melt Extruded Pelletization}}},
year = {{2017}},
}
@misc{12143,
author = {{Vo, A. and Kutz, Gerd and He, H. and Zang, J. and Kim, D. and Kim, S. and Repka, M.}},
location = {{San Diego (USA)}},
title = {{{Continuous Manufacturing of NSAID Delayed Release Pellets by Hot Melt Extrusion Technology: Application of QbD Space Design, Inline FT-NIR, and Inline Pellet Size Analysis}}},
year = {{2017}},
}
@misc{12144,
author = {{Kamke, Dominic and Scherbaum, B. and Daniels, R. and Kutz, Gerd}},
location = {{Krakau}},
title = {{{One formulation, four granulation techniques - Comparison of energy consumption}}},
year = {{2017}},
}
@article{2351,
author = {{Deffner, Bernd and Jimaja, Sètuhn and Kröger-Brinkmann, Anja and Schlüter, A. Dieter}},
issn = {{1022-1352}},
journal = {{Macromolecular Chemistry and Physics}},
title = {{{Tensile Behavior of a Substituted Poly(m-,p-phenylene) versus Its Parent Counterpart and Synthesis of Related Polyarylenes}}},
doi = {{10.1002/macp.201600561}},
year = {{2017}},
}
@article{2620,
author = {{Nolte, T. and Hölscher, Maike and Upmann, Matthias and Zapp, Jürgen}},
journal = {{Deutsche Lebensmittel-Rundschau}},
number = {{1}},
pages = {{17--21}},
title = {{{Fehlaromen in der Ebermast. Ebergeruchsanalytik im Vergleich}}},
volume = {{113}},
year = {{2017}},
}
@inproceedings{2621,
author = {{Upmann, Matthias}},
location = {{Schwelentrup}},
title = {{{Schnitzel & Co - Auslaufmodelle der Ernährung?}}},
year = {{2017}},
}
@inproceedings{2622,
author = {{Upmann, Matthias and Lautenschläger, Ralf}},
location = {{Düsseldorf}},
title = {{{Fleisch vom Bruderhahn - einsetzbar und zielführend für hochwertige Fleischerzeugnisse?}}},
year = {{2017}},
}
@inproceedings{2623,
author = {{Nolte, T. and Hölscher, Maike and Upmann, Matthias and Zapp, Jürgen}},
location = {{Bad Salzuflen}},
title = {{{Detektion von Ebergeruchsstoffen - analytisch chemische Aspekte}}},
year = {{2017}},
}
@inproceedings{2624,
author = {{Hölscher, Maike and Nolte, T. and Zapp, Jürgen and Stiebing, Achim and Lautenschläger, Ralf and Upmann, Matthias}},
location = {{ Bad Salzuflen}},
title = {{{Verarbeitung von Eberfleisch - Möglichkeiten und Grenzen}}},
year = {{2017}},
}
@article{2625,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{7}},
pages = {{60--64}},
title = {{{Was ist erlaubt, was verboten? 13. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost}}},
volume = {{97}},
year = {{2017}},
}
@article{2626,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{44--50}},
title = {{{Was ist erlaubt, was verboten? 13. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost}}},
volume = {{97}},
year = {{2017}},
}
@inproceedings{2627,
author = {{Fencher, T. and Upmann, Matthias}},
location = {{Garmisch-Partenkirchen}},
title = {{{Digitale Knochenpartikelanalyse}}},
year = {{2017}},
}
@inproceedings{2628,
author = {{Fencher, T. and Röser, Anja and Upmann, Matthias}},
location = {{Garmisch-Partenkirchen}},
title = {{{Histologische Knochenpartikelfärbungen im Vergleich – Genauigkeit von Alizarin, Kossa und Co. }}},
year = {{2017}},
}
@inproceedings{2629,
author = {{Upmann, Matthias and Langen, M.}},
location = {{Berlin}},
title = {{{Separation von Fleischstandards. Anforderungen an Ausgangsmaterial, Prozesse und Produkte}}},
year = {{2017}},
}
@article{2631,
author = {{Lautenschläger, Ralf and Upmann, Matthias}},
journal = {{Animal Frontiers}},
pages = {{2--4}},
title = {{{How meat is defined in the European Union and in Germany}}},
volume = {{1}},
year = {{2017}},
}
@inproceedings{2633,
author = {{Upmann, Matthias}},
location = {{Bochum}},
title = {{{Verarbeitung von Eberfleisch. Auswirkungen auf die Qualität von Fleischprodukten}}},
year = {{2017}},
}
@inproceedings{2635,
author = {{Upmann, Matthias}},
location = {{ Neuchâtel }},
title = {{{Muscle cell integrity – crucial for meat product quality?}}},
year = {{2017}},
}
@inproceedings{2638,
author = {{Upmann, Matthias and Lautenschläger, Ralf}},
location = {{Lemgo}},
title = {{{Qualitätsprodukte aus dem Fleisch von Bruderhähnen - Realität oder Fiktion?}}},
year = {{2017}},
}
@article{2885,
author = {{Kutz, Gerd}},
issn = {{0938-2216}},
journal = {{Haut}},
number = {{6}},
pages = {{324--329}},
publisher = {{WPV, Wirtschafts- und Praxisverlag GmbH }},
title = {{{Zur Galenik topischer Lichtschutzmittel Haut}}},
volume = {{XXVVIII}},
year = {{2017}},
}
@misc{2920,
author = {{Hernández Rodriguez, Tanja and Kern, S. and Platas Barradas, O. and Pörtner, R. and Frahm, Björn}},
location = {{Lemgo, Germany}},
title = {{{Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren}}},
year = {{2017}},
}
@misc{2921,
author = {{Pörtner, R. and Möller, J. and Hernández Rodriguez, Tanja and Frahm, Björn and Hass, V. C.}},
location = {{Neu-Ulm, Germany}},
title = {{{Model-assisted design and optimization of biotechnological processes}}},
year = {{2017}},
}
@misc{2950,
author = {{Hernández Rodriguez, Tanja and Koopmann, K. S. and Klaes, J. and Kern, S. and Platas Barradas, O. and Pörtner, R. and Frahm, Björn}},
location = {{Munic, Germany}},
title = {{{Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren}}},
year = {{2017}},
}
@misc{2994,
author = {{Hernández Rodriguez, Tanja and Koopmann, K. S. and Pörtner, R. and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{Influence of parameter accuracies in cell culture seed train simulations}}},
year = {{2017}},
}
@misc{2995,
author = {{Hernández Rodriguez, Tanja and Krull, S. and Hass, V. C. and Möller, J. and Pörtner, R. and Frahm, Björn}},
location = {{Lausanne, Switzerland}},
title = {{{Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization}}},
year = {{2017}},
}
@misc{2996,
author = {{Hernández Rodriguez, Tanja and Krull, S. and Hass, V. C. and Pörtner, R. and Frahm, Björn}},
location = {{Neu-Ulm, Germany}},
title = {{{Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization}}},
year = {{2017}},
}
@inproceedings{3326,
author = {{Kutz, Gerd}},
location = {{Nürnberg}},
title = {{{Überwachung von Schmelz- und Feuchtgranulationsprozessen in Intensivmischern mit Hilfe der Parsum-Sonde}}},
year = {{2017}},
}
@inproceedings{3329,
author = {{Kutz, Gerd}},
booktitle = {{Teil 11: Symposium der GD Task Force „Licht.Hautkrebs.Prävention“: Prävention von hellem Hautkrebs im privaten und im beruflichen Bereich}},
location = {{München}},
title = {{{Galenik von aktuellen topischen Lichtschutzmitteln}}},
year = {{2017}},
}
@inproceedings{5574,
author = {{Rossmann, Sören and Wolff, V. and Müller, Ulrich and Schneider, Jan}},
location = {{Bruchsal}},
title = {{{Einfluss forcierter Lagerbedingungen auf die physikalische Alterung von Getränkeemulsionen}}},
year = {{2017}},
}
@article{5576,
author = {{Broeker, Timo and Hoffarth, Marc and Oppermann, L. and Wolff, V. and Neubauer, Pia Rebecca and Schneider, Jan}},
journal = {{BrewingScience}},
number = {{3-4}},
pages = {{74--84}},
title = {{{Oxidation of Brewers Spent Grain for the Release of Fermentable Sugars by Direct Pretreatment in an Electrolysis Reactor}}},
volume = {{70}},
year = {{2017}},
}
@inproceedings{5578,
author = {{Rossmann, Sören and Wolff, V. and Müller, Ulrich and Schneider, Jan}},
location = {{ Ljubljan (Slovenia}},
title = {{{Comparative study of accelerated shelf-life tests on physical ageing of beverages containing weighted flavor emulsions}}},
year = {{2017}},
}
@inproceedings{5579,
author = {{Schneider, Jan and Hoffarth, Marc and Broeker, Timo}},
location = {{Ljubljana (Slovenia)}},
title = {{{Wet oxidation of spent grains from breweries for the production of fermentable sugars}}},
year = {{2017}},
}
@inproceedings{5580,
author = {{Broeker, Timo and Hoffarth, Marc and Heikrodt, Klaus and Schneider, Jan}},
location = {{Ljubljana (Slovenia)}},
title = {{{Study on the implementation of a biocatalytic power-to-gas reactor in a brewery}}},
year = {{2017}},
}
@inproceedings{5581,
author = {{Conradi, Florian and Wefing, Patrick}},
location = {{Lemgo}},
title = {{{Innovation in der Brauerei - Konzept einer kontinuierlichen Maischeanalge durch intelligente Vernetzung mit moderner Sensortechnik}}},
year = {{2017}},
}
@inproceedings{5582,
author = {{Hoffarth, Marc}},
location = {{Lemgo}},
title = {{{Biokatalytische Methanisierung - Synthetisches Erdgas aus regenerativen Quellen}}},
year = {{2017}},
}
@inproceedings{5583,
author = {{Broeker, Timo}},
location = {{Lemgo}},
title = {{{Bioraffinerie und Sektorenkopplung – biokatalytische Methanisierung als Schlüsseltechnologie zur Implementierung von Power-to-Gas}}},
year = {{2017}},
}
@inproceedings{5584,
author = {{Broeker, Timo}},
location = {{Gelsenkirchen}},
title = {{{bioCONNECT - Wasserstoff und biogenes CO2 im Verbund}}},
year = {{2017}},
}
@inproceedings{5585,
author = {{Broeker, Timo and Hoffarth, Marc and Heikrodt, Klaus and Schneider, Jan}},
location = {{Barcelona/Katalonia}},
title = {{{Study on the implementation of a biocatalytic power-to-gas reactor in a brewery}}},
year = {{2017}},
}
@inproceedings{6182,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
location = {{Kigali/ Rwanda}},
title = {{{Mechanical Steam Treatment (MSD) of plant material}}},
year = {{2017}},
}
@inproceedings{6183,
author = {{Müller, Ulrich and Rossmann, S. and Merck, C. and Schneider, Jan}},
location = {{Kigali/ Rwanda}},
title = {{{Direct Homogenization of Beverage Emuslions with the innovative Counterflow Injection Process}}},
year = {{2017}},
}
@inproceedings{6184,
author = {{Müller, Ulrich}},
location = {{Fulda}},
title = {{{Entkeimung von Kräutern und Gewürzen – eine Übersicht über aktuelle Verfahren}}},
year = {{2017}},
}
@misc{12975,
abstract = {{Properly handled fish is usually marketed as “fresh fish” until day 10 after fishing. About 40% of the total fishery that is used for direct human consumption is marketed in fresh form stored at temperatures up to +2 °C. Currently, there are no validated methods available for controlling the recommended period of storage. Apart from being a potential source for food fraud, spoiled fish represents a major source of foodborne illnesses and intoxications.
In this study, a rapid MALDI-TOF mass spectrometry based screening method was developed using the vitreous fluid of fish eyes as specimen for the examination of different days of storage. The vitreous fluid was collected from n = 100 freshly fished brown trouts at day 0, 3, 7, 9, and 11 post mortem (n = 20 brown trouts each day of examination). The samples were immediately measured by MALDI-TOF mass spectrometry in linear positive mode (mass range m/z 2000–20,000 Da). For quality assurance the experiment was repeated with a set of brown trouts (n = 100) originating from the same fish farm and with brown trouts (n = 100) originating from a different fish farm. For specificity testing rainbow trouts (n = 10) were examined accordingly. All obtained mass spectra were processed by means of MALDI Biotyper OC 3.1 and ClinProTools 3.0 software.
The MALDI Biotyper approach showed limited applicability for the identification of the time of storage. However, it was suitable to reliably discriminate between the closely related species brown and rainbow trout. Processing by ClinProTools revealed four crucial mass peaks (m/z 2594 Da, m/z 4857 Da, m/z 4879 Da, m/z 4899 Da) which enabled a reliable differentiation between day 0 and 3, 7, 9, 11 (rate of correct identification > 90%) as well as the differentiation between day 3 and 7, 9, 11 (rate of correct identification > 72%). However, this approach showed limited applicability within the end of the tested period of storage when comparing between day 7, 9, or 11.}},
author = {{Ulrich, Sebastian and Beindorf, Philipp–Michael and Biermaier, Barbara and Schwaiger, Karin and Gareis, Manfred and Gottschalk, Christoph}},
booktitle = {{Food Control}},
issn = {{0956-7135}},
keywords = {{MALDI-TOF, Mass spectrometry, Freshness, Fish, Quality control, Authenticity}},
number = {{10}},
pages = {{281--289}},
publisher = {{Elsevier }},
title = {{{A novel approach for the determination of freshness and identity of trouts by MALDI-TOF mass spectrometry}}},
doi = {{10.1016/j.foodcont.2017.05.005}},
volume = {{80}},
year = {{2017}},
}
@misc{12976,
abstract = {{The consumption of edible insects (entomophagy) will gain greater significance facing the increasing global population, which is suggested to reach 9 billion people in 2050 (FAO., 2009). Due to their high amount of proteins, fatty acids, vitamins, and minerals insects represent a valuable source of essential nutrients.
While the consumption of insects is very common in many countries of Africa and Asia, there is a far smaller acceptance for entomophagy in Western cultures. Though, products such as noodles or burger paddies made from insect meal have a better compliance and can already be purchased in some countries of the European Union. This processing step however involves the risk of adulteration, because there is no more possibility to authenticate the insects once they are ground.
The aim of this study was to investigate whether edible insects could be measured and distinguished by MALDI-TOF MS (matrix-assisted laser desorption ionization-time of flight mass spectrometry). Therefore, different kinds of edible insects (buffalo worms, mealworms, crickets and grasshoppers) were purchased via online shops and ground subsequently. The insect powder was extracted by vigorously shaking in diluted formic acid and measured by MALDI-TOF MS. The measurement provided reproducible as well as specific mass spectra and enabled a precise differentiation of the different species.}},
author = {{Ulrich, Sebastian and Kühn, Ulrike and Biermaier, Barbara and Piacenza, Nicolo and Schwaiger, Karin and Gottschalk, Christoph and Gareis, Manfred}},
booktitle = {{Food Control}},
issn = {{0956-7135}},
keywords = {{MALDI-TOF MS, Mass spectrometry, Edible insects, Authenticity, Food quality}},
number = {{6}},
pages = {{96--101}},
publisher = {{Elsevier}},
title = {{{Direct identification of edible insects by MALDI-TOF mass spectrometry}}},
doi = {{10.1016/j.foodcont.2017.01.010}},
volume = {{76}},
year = {{2017}},
}
@misc{12038,
author = {{Kamke, Dominic and Kutz, Gerd and Daniels, R. and Dietrich, S.}},
location = {{Glasgow (Großbritannien)}},
title = {{{Performance qualification of an inline particle sizing probe}}},
year = {{2016}},
}
@book{2379,
author = {{Becker, Barbara and Pfannebecker, Jens}},
isbn = {{978-3-95468-388-8}},
pages = {{80}},
publisher = {{Behr`s Verlag}},
title = {{{Lebensmittelassoziierte Viren - Norovirus }}},
year = {{2016}},
}
@inbook{2395,
author = {{Pörtner, R. and Platas Barradas, O. and Frahm, Björn and Hass, V.C.}},
booktitle = {{Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls}},
isbn = {{978-0-444-63663-8}},
pages = {{463--493}},
publisher = {{Elsevier}},
title = {{{Advanced Process and Control Strategies for Bioreactors}}},
doi = {{10.1016/b978-0-444-63663-8.00016-1}},
year = {{2016}},
}
@article{2437,
author = {{Upmann, Matthias and Weyland, Gerd}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{32--35}},
publisher = {{Dt. Fachverl.}},
title = {{{Was ist erlaubt, was verboten? 12. Lemgoer Lebensmittelrechtstagung Fleisch+ Feinkost- Teil2}}},
volume = {{96}},
year = {{2016}},
}
@article{2552,
author = {{Weyland, Gerd and Stiebing, Achim}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft : von der Erzeugung bis zur Vermarktung von Lebensmitteln tierischen Ursprungs}},
number = {{9}},
pages = {{70 -- 73}},
title = {{{Was ist erlaubt. was verboten? 10. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost- Teil 2}}},
volume = {{94}},
year = {{2016}},
}
@article{2554,
author = {{Weyland, Gerd and Stiebing, Achim}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft : von der Erzeugung bis zur Vermarktung von Lebensmitteln tierischen Ursprungs}},
number = {{8}},
pages = {{45 -- 48}},
title = {{{Was ist erlaubt, was verboten? : 10. Lemgoer Lebensmitte lrechtstagung Fleisch+ Feinkost- Teil 1}}},
volume = {{94}},
year = {{2016}},
}
@article{2556,
author = {{Weyland, Gerd and Stiebing, Achim}},
journal = {{Fleischwirtschaft : von der Erzeugung bis zur Vermarktung von Lebensmitteln tierischen Ursprungs}},
number = {{10}},
pages = {{57 -- 61}},
title = {{{Was ist erlaubt, was verboten? 10. Lemgoer Lebensmittelrechtstagung Fleisch+ Feinkost- Teil 3}}},
volume = {{94}},
year = {{2016}},
}
@inproceedings{2609,
author = {{Upmann, Matthias}},
location = {{Lemgo}},
title = {{{Emotionen rund ums's Schnitzel. Versuch einer Versachlichung}}},
year = {{2016}},
}
@inproceedings{2610,
author = {{Upmann, Matthias}},
location = {{Berlin}},
title = {{{Erhitztes Bindegewebe in Rohwurst. Eine Schönung des Produkts?}}},
year = {{2016}},
}
@inproceedings{2611,
author = {{Upmann, Matthias}},
location = {{Sankt Augustin}},
title = {{{Fleisch vom Bruderhahn – ein besonderes Fleisch?}}},
year = {{2016}},
}
@inproceedings{2612,
author = {{Stiebing, A. and Upmann, Matthias and Lautenschläger, Ralf}},
location = {{Frankfurt/Main}},
title = {{{Verzehrs- und Verarbeitungseigenschaften von Eberfleisch}}},
year = {{2016}},
}
@inproceedings{2613,
author = {{Upmann, Matthias and Röser, Anja and Kaufeld, N.}},
location = {{Garmisch-Partenkirchen}},
title = {{{Histologischer Nachweis von Verdickungsmitteln: Färbestrategie zur Unterscheidung verschiedener Stoffe}}},
year = {{2016}},
}
@inproceedings{2614,
author = {{Upmann, Matthias and Hölscher, M. and Nolte, T. and Zapp, Jürgen and Lautenschläger, Ralf and Stiebing, Achim}},
location = {{Garmisch-Partenkirchen}},
title = {{{Verarbeitung von geruchsabweichendem Eberfleisch. Möglichkeiten und Grenzen.}}},
year = {{2016}},
}
@inproceedings{2615,
abstract = {{Vortrag und Tagungsbandbeitrag}},
author = {{Hölscher, Maike and Nolte, T. and Zapp, Jürgen and Stiebing, Achim and Lautenschläger, Ralf and Upmann, Matthias}},
location = {{Lemgo}},
title = {{{Verarbeitungseignung von Eberfleisch}}},
year = {{2016}},
}
@inproceedings{2616,
author = {{Nolte, T. and Hölscher, M. and Upmann, Matthias and Kothe, A. and Zapp, Jürgen}},
location = {{Lemgo}},
title = {{{Fehlaromen in Eberfleischprodukten. Aktuelle Erkenntnisse.}}},
year = {{2016}},
}
@inproceedings{2617,
author = {{Upmann, Matthias and Langen, M.}},
location = {{Lemgo}},
title = {{{Separation verschiedener Fleischstandards. Neue Anforderungen an technologische Verfahren.}}},
year = {{2016}},
}
@article{2618,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{43--46}},
title = {{{Was ist erlaubt, was verboten? 12. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 1}}},
volume = {{96}},
year = {{2016}},
}
@article{2619,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{12}},
pages = {{46--50}},
title = {{{Was ist erlaubt, was verboten? 12. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 3}}},
volume = {{96}},
year = {{2016}},
}
@inproceedings{4459,
author = {{Kutz, Gerd}},
location = {{Köln}},
title = {{{APV basics}}},
year = {{2016}},
}
@misc{2991,
author = {{Beshay, U. and Feldt, Sebastian and Schwarze, B. and Wefing, P. and Hahne, T. and Moschinski, J. and Müller, C. and Büker, R. and Kramer, M. and Brod, H. and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{DMA Photobioreactor System – Cultivation at low shear stress and optional membrane aeration}}},
year = {{2016}},
}
@misc{2992,
author = {{Hernández Rodriguez, Tanja and Vörtler, S. and Kern, S. and Platas Barradas, O. and Pörtner, R. and Frahm, Björn}},
location = {{Recklinghausen, Germany}},
title = {{{A software tool for biopharmaceutical seed train design and optimization}}},
year = {{2016}},
}
@misc{2993,
author = {{Koopmann, K. S. and Hernández Rodriguez, Tanja and Vörtler, S. and Beshay, U. and Möller, J. and Pörtner, R. and Frahm, Björn}},
location = {{Koblenz, Germany}},
title = {{{Simulation of cell culture seed trains – investigation of the influence of parameter inaccuracies}}},
year = {{2016}},
}
@article{3331,
author = {{Kutz, Gerd and Kamke, Dominic}},
issn = {{2191-8341}},
journal = {{TechnoPharm : making science work}},
number = {{5}},
pages = {{290--294}},
publisher = {{ECV}},
title = {{{ Innovativer Ansatz zur Prozesskontrolle bei der Granulation im Intensivmischergranulator (Teil 2)}}},
volume = {{6}},
year = {{2016}},
}
@article{3332,
author = {{Kutz, Gerd and Kamke, Dominic}},
issn = {{2191-8341}},
journal = {{TechnoPharm : making science work }},
number = {{4}},
pages = {{234--239}},
publisher = {{ECV}},
title = {{{Innovativer Ansatz zur Prozesskontrolle bei der Granulation im Intensivmischergranulator (Teil 1)}}},
volume = {{6}},
year = {{2016}},
}
@inproceedings{3333,
author = {{Kutz, Gerd}},
location = {{Köln}},
publisher = {{TÜV Rheinland LGA Products GmbH}},
title = {{{Anforderungen an die aseptische Herstellung}}},
year = {{2016}},
}
@inproceedings{3341,
author = {{Kutz, Gerd}},
location = {{Köln}},
publisher = {{TÜV Rheinland LGA Products GmbH}},
title = {{{Sterilfiltration}}},
year = {{2016}},
}
@inproceedings{3395,
author = {{Kutz, Gerd}},
location = {{Köln}},
publisher = {{TÜV Rheinland LGA Products GmbH}},
title = {{{Filterintegritätstests }}},
year = {{2016}},
}
@inproceedings{3396,
author = {{Kutz, Gerd}},
location = {{TÜV Rheinland LGA Products GmbH in Köln.}},
title = {{{Sterilisations- und Desinfektionsverfahren}}},
year = {{2016}},
}
@inproceedings{3397,
author = {{Kutz, Gerd}},
location = {{TÜV Rheinland LGA Products GmbH in Köln}},
title = {{{Media Fill - Prozesssimulation mit Nährmedien}}},
year = {{2016}},
}
@inproceedings{3416,
author = {{Kutz, Gerd}},
location = {{Bonn}},
title = {{{Messmethoden (sichtbare Partikel), Methoden des Ph. Eur}}},
year = {{2016}},
}
@inproceedings{3417,
author = {{Kutz, Gerd}},
location = {{Tübingen}},
title = {{{Qualifizierung, Kalibrierung, Reinigungsvalidierung, Prozessparameter, Prozessvalidierung}}},
year = {{2016}},
}
@article{3418,
author = {{Kutz, Gerd and Kamke, Dominic}},
issn = {{1434-8942 }},
journal = {{ Pharma + Food : Effizienz im Hygieneprozess : Ausrüstung, Produktion, Organisation}},
number = {{4}},
pages = {{36--38}},
publisher = {{Hüthig}},
title = {{{Dem Intensivmischer auf der Spur: Echtzeit- Prozesskontrolle}}},
year = {{2016}},
}
@inproceedings{5535,
author = {{Zapp, Jürgen and Pfender, S. and Schneider, Jan}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Stabilität eines Melatonin-haltigen funktionellen Getränkes}}},
year = {{2016}},
}
@inproceedings{5536,
author = {{Kothe, Achim and Krieger, O. and Seidel, Leopold and Nolte, Timo and Zapp, Jürgen}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Antioxidantien in Tee - HPLC-Screening mittels Nachsäulenderivatisierung}}},
year = {{2016}},
}
@inproceedings{5537,
author = {{Seidel, Leopold and Kothe, Achim and Zapp, Jürgen}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Triterpene in der Apfelschale von alten und neuen Apfelsorten}}},
year = {{2016}},
}
@inproceedings{5538,
author = {{Danneel, Hans-Jürgen}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Fünf Jahre ILT.NRW}}},
year = {{2016}},
}
@inproceedings{5540,
author = {{Tachil, Jörg and van Bracht, Hendrik and Danneel, Hans-Jürgen}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Prozesschromatographische Fraktionierung von Proteinhydrolysaten}}},
year = {{2016}},
}
@misc{5541,
author = {{Reichl, Norbert and Brunklaus, Sabine and Danneel, Hans-Jürgen and Müller, Ulrich and Gebauer, Simone and Kolkmann, Beate and Höfel, Sabine}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
editor = {{Buckenhüskes, Herbert J.}},
location = {{Lemgo}},
publisher = {{Gesellschaft Deutscher Lebensmitteltechnologen}},
title = {{{Lebensmittel 4.0 - Chancen für den Mittelstand? Ergebnisse einer Unternehmensbefragung. Welche Chancen und Potentiale birgt das Thema Digitalisierung? Wir befragten - Unternehmen antworteten}}},
year = {{2016}},
}
@inproceedings{5544,
author = {{Schneider, Jan}},
booktitle = {{TWA der VLB Berlin e. V., Berlin, 24.10.2016}},
location = {{Berlin}},
title = {{{Smart Food Technology – eine neue Partnerschaftinitiative von Hochschule und Industrie: welches Potenzial hat die Digitalisierung?}}},
year = {{2016}},
}
@inproceedings{5545,
author = {{Hoffarth, Marc and Broeker, Timo and Wolff, V. and Mengedoth, C. and Heikrodt, Klaus and Schneider, Jan}},
booktitle = {{2. Fachforum Biologische Methanisierung, Regensburg, 25.10.2016}},
location = {{Regensburg}},
title = {{{ Synergies between biocatalytic methanation of Power-To-Gas hydrogen with carbon dioxide from alcoholic fermentation}}},
year = {{2016}},
}
@inproceedings{5546,
author = {{Schneider, Jan}},
booktitle = {{Forum Brau Beviale, Nürnberg, 10.11.2016}},
location = {{Nürnberg}},
title = {{{Hochschule Ostwestfalen-Lippe: vom Bachelor über den Master zur Promotion am Graduiertenzentrum OWL}}},
year = {{2016}},
}
@inproceedings{5547,
author = {{Schwarzer, Knut and Wilhelm, Patrick and Schneider, Jan and Müller, Ulrich}},
booktitle = {{Annual Meeting des American Institute of Chemical Engineers (AIChE), Posterbeitrag, San Francisco, 13.-18.11.2016}},
isbn = {{978-0-8169-1097-7}},
location = {{San Francisco}},
publisher = {{Wiley-VCH GmbH}},
title = {{{The Lemgo D- and z-value database for food – An instrument for the dimensioning of pasteurization process}}},
year = {{2016}},
}
@inproceedings{5548,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
booktitle = {{Annual Meeting des American Institute of Chemical Engineers (AIChE), Vortrag, San Francisco, 13.-18.11.2016}},
location = {{San Francisco}},
title = {{{Mechanical steam treatment of plant material}}},
year = {{2016}},
}
@inproceedings{5549,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
booktitle = {{Annual Meeting des American Institute of Chemical Engineers (AIChE), Posterbeitrag, San Francisco, 13.-18.11.2016}},
location = {{San Francisco}},
title = {{{A comparison of the static and dynamic freeze-drying by means of modelling}}},
year = {{2016}},
}
@inproceedings{5550,
author = {{Rossmann, Sören and Schneider, Jan and Müller, Ulrich and Kohlus, R.}},
booktitle = {{Annual Meeting des American Institute of Chemical Engineers (AIChE), Posterbeitrag, San Francisco, 13.-18.11.2016}},
location = {{San Francisco}},
title = {{{Direct homogenization of beverage emulsions with the innovative counterflow injection process}}},
year = {{2016}},
}
@inproceedings{5551,
author = {{Huchtmann, Julian and Aufzug, M. and Schneider, Jan}},
booktitle = {{DLG-Forum FoodTec, Frankfurt-Rodgau, 23.11.2016}},
location = {{Frankfurt-Rodgau}},
title = {{{Entwicklung eines funktionellen Getränks zur Linderung des Hangover „Glory Mornin“}}},
year = {{2016}},
}
@inproceedings{5552,
author = {{Broeker, Timo and Blöhse, D. and Bittner, J. and Hoffarth, Marc and Ramke, Hans-Günter and Heikrodt, Klaus and Schneider, Jan}},
booktitle = {{NRW-Biokraftstofftagung - Haus Düsse - Landwirtschaftskammer NRW, Bad Sassendorf, 24.11.2016}},
location = {{Bad Sassendorf}},
title = {{{Biokatalytische Methanisierung im Pilotmaßstab }}},
year = {{2016}},
}
@inproceedings{5553,
author = {{Schneider, Jan}},
booktitle = {{Lebensmittel 4.0, Vortrag, Lemgo, 12.12.2016}},
location = {{Lemgo}},
title = {{{Potenziale von Industrie 4.0 in der Qualitätssteuerung}}},
year = {{2016}},
}
@article{5554,
author = {{Pliske, Roland and Haase, M. and Müller, Ulrich and Kohlus, R.}},
issn = {{0009-286X }},
journal = {{Chemie-Ingenieur-Technik }},
number = {{8}},
pages = {{1169--1176}},
publisher = {{Wiley-VCH}},
title = {{{Prozesscharakterisierung der dynamischen Gefriertrocknung in einem Feststoffmischer }}},
volume = {{88}},
year = {{2016}},
}
@inproceedings{6181,
author = {{Rossmann, S. and Schneider, Jan and Müller, Ulrich and Kohlus, R.}},
location = {{Lemgo}},
title = {{{Einfluss verschiedener Forciermethoden auf die Stabilität und den Trübungsverlust von 20 Getränkeemulsionen}}},
year = {{2016}},
}
@inproceedings{5519,
author = {{Rossmann, Sören and Merck, C. and Schneider, Jan and Müller, Ulrich and Kohlus, R.}},
booktitle = {{ProcessNet-Jahrestagung Lebensmittelverfahrenstechnik (Poster), Erlangen, 03/2016}},
location = {{Erlangen}},
title = {{{Herstellung von Getränkeemulsionen mit dem innovativen Gegenstrominjektionsverfahren}}},
year = {{2016}},
}
@inproceedings{5521,
author = {{Müller, Ulrich and Pliske, Roland and Kohlus, R. and Weber, H.}},
booktitle = {{ProcessNet-Fachgruppe Lebensmittelverfahrenstechnik (Vortrag), Erlangen, 09.-11.03.2016}},
location = {{Erlangen}},
title = {{{Untersuchungen zur Aktivität gefriergetrockneter und revitalisierter Pediococcus pentosaceus-Starterkulturen }}},
year = {{2016}},
}
@inproceedings{5522,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
booktitle = {{ProcessNet-Jahrestagung Lebensmittelverfahrenstechnik, Erlangen, 09.-11.03.2016}},
location = {{Erlangen}},
title = {{{Vergleich der statischen und dynamischen Gefriertrocknung mittels Modellierung}}},
year = {{2016}},
}
@article{5523,
author = {{Damman, Anna and Schwarzer, Knut and Schneider, Jan}},
issn = {{1619-537X}},
journal = {{Brauwelt. En español }},
pages = {{116--119}},
publisher = {{Fachverlag Hans Carl GmbH}},
title = {{{Examen de instalaciones de pasteurizatión}}},
year = {{2016}},
}
@article{5524,
author = {{Schneider, Jan}},
issn = {{2509-8853 }},
journal = {{ Getränke + Lebensmittel Herstellung : Inhaltsstoffe + Technik + Logistik : Informationen für die Wirtschaft}},
publisher = {{Kuhn}},
title = {{{Thema 2016: Morgen ist heute schon gestern. Unbeständigkeit - Segen oder Fluch?}}},
year = {{2016}},
}
@misc{5525,
author = {{Wiese, T. and Brunklaus, Sabine and Danneel, Hans-Jürgen and Reichl, N.}},
booktitle = {{Lebensmitteltechnik }},
issn = {{0047-4290 }},
number = {{12}},
pages = {{52}},
publisher = {{ Hamburg}},
title = {{{Mit Fokus auf "Lebensmittel 4.0" - Ein Projekt an der Hochschule Ostwestfalen-Lippe widmet sich dem digitalen Wandel}}},
volume = {{48}},
year = {{2016}},
}
@inproceedings{5526,
author = {{Hoffarth, Marc}},
booktitle = {{Plattformtreffen Netzwerk Brenstoffzelle und Wasserstoff, ZBT Duisburg}},
location = {{Duisburg}},
title = {{{Neumitgliedervorstellung Netzwerk Brennstoffzelle und Wasserstoff}}},
year = {{2016}},
}
@inproceedings{5528,
author = {{Rossmann, Sören and Merck, C. and Kohlus, R. and Schneider, Jan and Müller, Ulrich}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 21.10.2016}},
location = {{Lemgo}},
title = {{{Einfluss der Prozessparametrierung auf die Qualität von Getränkeemulsionen beim Gegenstrominjektionsverfahren}}},
year = {{2016}},
}
@inproceedings{5529,
author = {{Lütke Föller, Anna and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich and Ollesch, K. and Schiller, T.}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 21.10.2016}},
location = {{Lemgo}},
title = {{{Erste Erfahrungen mit einer Strömungszelle zur Aufnahme von Reinigungskinetiken von Werkstoffoberflächen}}},
year = {{2016}},
}
@inproceedings{5530,
author = {{Walter, S. and Steffens, M. and Zapp, Jürgen and Schneider, Jan}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Stabilität von mit funktionellen Caseinhydrolysaten angereicherten fruchtsafthaltigen Getränken }}},
year = {{2016}},
}
@inproceedings{5531,
author = {{Rossmann, S. and Kohlus, R. and Müller, Ulrich and Schneider, Jan}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Einfluss forcierter Lagerbedingungen auf die chemisch-physikalische Stabilität von Getränkeemulsionen}}},
year = {{2016}},
}
@inproceedings{5532,
author = {{Schwarzer, Knut and Gerke, S. and Wolff, V. and Schneider, Jan}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Pasteurisation von Obstkonserven - Auswirkung der Gebindeform, der Viskosität und der Stückigkeit des Pasteurisationsgutes auf die tatsächlich applizierten Pasteurisationseinheiten}}},
year = {{2016}},
}
@inproceedings{5533,
author = {{Nolte, Timo and Wittkötter, K. and Zapp, Jürgen}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Fehlaromen in der Eberfleischproduktion - Aktuelle Erkenntnisse}}},
year = {{2016}},
}
@inproceedings{5534,
author = {{Westerholt, J. and Zapp, Jürgen}},
booktitle = {{GDL-Kongress Lebensmitteltechnologie (Vortrag und Tagungsbandbeitrag), Lemgo, 20.-22.10.2016}},
location = {{Lemgo}},
title = {{{Einfluss des Röstverfahrens auf die Bekömmlichkeit von Kaffee unter besonderer Berücksichtigung organischer Säuren}}},
year = {{2016}},
}
@misc{12977,
abstract = {{Stachybotrys (S.) spp. are omnipresent cellulolytic molds. Some species are highly toxic owing to their ability to synthesize various secondary metabolites such as macrocyclic trichothecenes or hemolysins. The reliable identification of Stachybotrys at species level is currently limited to genome-based identification. This study aimed to establish a fast and reliable MALDI-TOF MS identification method by optimizing the pre-analytical steps for protein extraction for subsequent generation of high-quality fingerprint mass spectra. Eight reference strains of the American Type Culture Collection and the Technical University of Denmark were cultivated in triplicate (biological repetitions) for 2 days in malt extract broth. The mycelia (1.5 ml) were first washed with 75 % ethanol and an additional washing step with dimethyl sulfoxide (10 %) was added to remove unspecific low weight masses. Furthermore, mycelia were broken with roughened glass beads in formic acid (70 %) and acetonitrile. The method was successfully applied to a total of 45 isolates of Stachybotrys originating from three different habitats (indoor, feed, and food samples; n = 15 each): Twenty-seven isolates of S. chartarum and 18 isolates of S. chlorohalonata could be identified by MALDI-TOF MS. The data obtained exactly matched those obtained by genome-based identification. The mean score values for S. chartarum ranged from 2.509 to 2.739 and from 2.148 to 2.622 for S. chlorohalonata with a very good reproducibility: the relative standard deviations were between 0.3 % and 6.8 %. Thus, MALDI-TOF MS proved to be a fast and reliable alternative to identification of Stachybotrys spp. by nucleotide amplification and sequencing.}},
author = {{Ulrich, Sebastian and Biermaier, Barbara and Bader, Oliver and Wolf, Georg and Straubinger, Reinhard K. and Didier, Andrea and Sperner, Brigitte and Schwaiger, Karin and Gareis, Manfred and Gottschalk, Christoph}},
booktitle = {{ Analytical & bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry, Analusis and Quimica analitica}},
issn = {{1618-2650}},
keywords = {{Stachybotrys spp, MALDI-TOF MS, Mass spectrometry, Filamentous fungi}},
number = {{27}},
pages = {{7565--7581}},
publisher = {{Springer}},
title = {{{Identification of Stachybotrys spp. by MALDI-TOF mass spectrometry}}},
doi = {{10.1007/s00216-016-9800-9}},
volume = {{408}},
year = {{2016}},
}
@article{2357,
author = {{Becker, Barbara and Nerenz, Heiko and Quadflieg, Jutta Maria and Schrader, Andreas and Becker, Verena }},
journal = {{SOFW-Journal : Home & personal care ingredients & formulations; Deutsche Ausgabe}},
number = {{11}},
pages = {{10--17}},
publisher = {{Verl. für Chemische Industrie, Ziolkowsky}},
title = {{{Phtoalexine als antimikrobielle Pflanzenwirkstoffe für die Kosmetik}}},
volume = {{140}},
year = {{2015}},
}
@article{2386,
author = {{Behler, Maximilian and Schulze, Christian and Schneider, Jan}},
issn = {{0341-7115 }},
journal = {{Brauindustrie}},
number = {{11}},
pages = {{92 -- 98}},
publisher = {{Sachon}},
title = {{{Hydrodynamische Effekte}}},
volume = {{100}},
year = {{2015}},
}
@misc{2389,
author = {{Kern, Simon and Platas-Barradas, Oscar and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{Cytotechnology}},
issn = {{1573-0778}},
number = {{4}},
pages = {{1019--1032}},
publisher = {{Springer}},
title = {{{Model-based strategy for cell culture seed train layout verified at lab scale}}},
doi = {{10.1007/s10616-015-9858-9}},
volume = {{68}},
year = {{2015}},
}
@article{2439,
author = {{Upmann, Matthias and Grünewald, Tanja and Gerhadt, Thomas and Hildebrandt, Goetz}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{87--91}},
publisher = {{Dt. Fachverl.}},
title = {{{Gewebliche Beschaffenheit von Kochpökelwaren : ALTS-Laborvergleichsuntersuchung zur histologischen Quantifizierung von Strukturzerstörungen}}},
volume = {{93}},
year = {{2015}},
}
@article{2597,
author = {{Upmann, Matthias and Lade, P.}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{109--112}},
title = {{{Knochenpartikel im Verarbeitungsfleisch für die Wurstproduktion}}},
volume = {{95}},
year = {{2015}},
}
@inproceedings{2598,
author = {{Lautenschläger, Ralf and Stiebing, Achim and Upmann, Matthias}},
location = {{Osnabrück}},
title = {{{Verarbeitungseigenschaften von Eberfleisch}}},
year = {{2015}},
}
@inproceedings{2599,
author = {{Upmann, Matthias}},
location = {{Garmisch-Partenkirchen}},
title = {{{Workshop Lebensmittelhistologie: Hackfleisch - Zerkleinerung}}},
year = {{2015}},
}
@article{2600,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{84--86}},
title = {{{Was ist erlaubt, was verboten? 11. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 2}}},
volume = {{95}},
year = {{2015}},
}
@article{2601,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{60--63}},
title = {{{Was ist erlaubt, was verboten? 11. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 3}}},
volume = {{95}},
year = {{2015}},
}
@article{2602,
author = {{Weyland, Gerd and Upmann, Matthias}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{51--53}},
title = {{{Was ist erlaubt, was verboten? 11. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 4}}},
volume = {{95}},
year = {{2015}},
}
@article{2603,
author = {{Schulze, G. and Upmann, Matthias}},
journal = {{Food & Recht Praxis}},
number = {{4}},
pages = {{9--11}},
title = {{{Herkunftskennzeichnung von Fleisch}}},
year = {{2015}},
}
@inproceedings{2604,
author = {{Upmann, Matthias and Hölscher, Maike and Lautenschläger, Ralf and Zapp, Jürgen and Stiebing, Achim}},
location = {{Herrsching}},
title = {{{Verzicht auf die Kastration durch Ebermast oder Immunokastration. Herausforderungen aus Sicht der Produktqualität}}},
year = {{2015}},
}
@article{2605,
author = {{Langen, M. and Klein, G. and Schigulski, S. and Upmann, Matthias}},
journal = {{Fleischwirtschaft}},
number = {{12}},
pages = {{61--63}},
title = {{{Furculafleisch ist kein Separatorenfleisch}}},
volume = {{95}},
year = {{2015}},
}
@inproceedings{4460,
author = {{Kutz, Gerd and Schubert, O. E.}},
location = {{Hochschule Ostwestfalen-Lippe Detmold}},
title = {{{APV basics}}},
year = {{2015}},
}
@inproceedings{4461,
author = {{Kutz, Gerd and Schubert, O. E.}},
location = {{Darmstadt}},
title = {{{APV basics}}},
year = {{2015}},
}
@article{2747,
author = {{Dammann, Anna and Schwarzer, Knut and Müller, Ulrich and Schneider, Jan}},
isbn = {{978-3-418-00847-9}},
journal = {{ Brewing science}},
number = {{Yearbook}},
pages = {{10 -- 17}},
title = {{{Evaluation of the Acidic Sucrose Hydrolysis as Time-Temperature Integrator in Flash Pasteurizers}}},
volume = {{2014}},
year = {{2015}},
}
@misc{2819,
author = {{Hernández Rodriguez, Tanja and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{BMC proceedings / BioMed Central}},
issn = {{1753-6561}},
publisher = {{BioMed Central}},
title = {{{Considerations for cell passaging in cell culture seed trains}}},
doi = {{10.1186/1753-6561-9-s9-p43}},
volume = {{9}},
year = {{2015}},
}
@misc{2820,
author = {{Kern, Simon and Platas Barradas, Oscar and Schaletzky, Martin and Sandig, Volker and Frahm, Björn and Pörtner, Ralf}},
booktitle = {{BMC proceedings / BioMed Central}},
issn = {{1753-6561}},
publisher = {{BioMed Central}},
title = {{{Model-based strategy for cell culture seed train layout verified at lab scale}}},
doi = {{10.1186/1753-6561-9-s9-p44}},
volume = {{9}},
year = {{2015}},
}
@misc{2917,
author = {{Frahm, Björn and Pörtner, R. and Kern, S. and Hernández Rodriguez, Tanja}},
location = {{Frankfurt am Main, Germany}},
title = {{{Seed train design and optimization for animal cell suspension culture}}},
year = {{2015}},
}
@misc{2919,
author = {{Frahm, Björn and Hernández Rodriguez, Tanja and Kern, S. and Koopmann, K. S. and Beshay, U. and Platas-Barradas, O. and Pörtner, R.}},
location = {{Magdeburg, Germany}},
title = {{{Seed train design and optimization for animal cell suspension culture}}},
year = {{2015}},
}
@misc{2985,
author = {{Hernández Rodriguez, Tanja and Pörtner, R. and Frahm, Björn}},
location = {{Hamburg, Germany}},
title = {{{Considerations for cell passaging in cell culture seed trains}}},
year = {{2015}},
}
@misc{2986,
author = {{Kern, S. and Platas, O. and Schaletzky, M. and Sandig, V. and Frahm, Björn and Pörtner, R.}},
location = {{Hamburg, Germany}},
title = {{{Model-based strategy for cell culture seed train layout verified at lab scale}}},
year = {{2015}},
}
@misc{2987,
author = {{Hernández Rodriguez, Tanja and Pörtner, R. and Frahm, Björn}},
location = {{Munic, Germany}},
title = {{{A software tool for biopharmaceutical seed train design and optimization}}},
year = {{2015}},
}
@misc{2988,
author = {{Hernández Rodriguez, Tanja and Pörtner, R. and Frahm, Björn}},
location = {{Barcelona, Spain}},
title = {{{Considerations for cell passaging in cell culture seed trains}}},
year = {{2015}},
}
@misc{2990,
author = {{Kern, S. and Platas, O. and Schaletzky, M. and Sandig, V. and Frahm, Björn and Pörtner, R.}},
location = {{Barcelona, Spain}},
title = {{{Model-based strategy for cell culture seed train layout verified at lab scale}}},
year = {{2015}},
}
@article{3398,
author = {{Balke, Tobias and Steffens, Marco and Schneider, Jan}},
issn = {{0016-9323 }},
journal = {{Getränke-Industrie Getränkewelt, Getränkewirtschaft}},
number = {{3}},
pages = {{22--26}},
publisher = {{Sachon}},
title = {{{Gemeinsam gegen den Geruch : Papatürk - Beispiel einer kooperativen Produktentwioklung}}},
volume = {{69}},
year = {{2015}},
}
@inproceedings{3422,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Filterintegritätstests}}},
year = {{2015}},
}
@inproceedings{3423,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Sterilfiltration}}},
year = {{2015}},
}
@inproceedings{3424,
author = {{Kutz, Gerd}},
location = {{Tübingen}},
title = {{{Neue Ansätze zur Prozessvalidierung und Prozesssteuerung: Herstellungsprozesse im Spiegel von EMA-, FDA-, ICH- und PIC/S- Empfehlungen}}},
year = {{2015}},
}
@inproceedings{3425,
author = {{Kutz, Gerd}},
location = {{Darmstadt}},
title = {{{Allgemeine Grundlagen zu Hitzesterilisationsverfahren}}},
year = {{2015}},
}
@inproceedings{3426,
author = {{Kutz, Gerd}},
location = {{Darmstadt}},
title = {{{Physikalische Grundlagen der Dampfsterilisation}}},
year = {{2015}},
}
@inproceedings{3427,
author = {{Kutz, Gerd}},
location = {{Bonn}},
title = {{{Überblick über Messmethoden und deren physikalischen Hintergründe: Sichtbare Partikel}}},
year = {{2015}},
}
@inproceedings{5555,
author = {{Broeker, Timo and Hoffarth, Marc and Schneider, Jan and Heikrodt, Klaus}},
location = {{Berlin}},
title = {{{ BioCO2nvert - Synergies of P2G und alcoholic CO2 for the efficient production of Methan and Bioethanol}}},
year = {{2015}},
}
@inproceedings{5556,
author = {{Broeker, Timo and Schneider, Jan and Otto, K.}},
location = {{Mertingen}},
title = {{{Energetische Verwertung von Trester aus der Fruchtsaftindustrie}}},
year = {{2015}},
}
@inproceedings{5557,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann_, Anna and Müller, Ulrich}},
location = {{Porto (Portugal)}},
title = {{{Determination of Pasteurization Units in a flash pasteurizers under consideration of heating and cooling sections and the residence time distribution}}},
year = {{2015}},
}
@article{5558,
author = {{Schneider, Jan}},
journal = {{Getränkeherstellung Deutschland}},
publisher = {{Kuhn Fachverlag GmbH & Co. KG}},
title = {{{Heute noch unrentabel und morgen schon die große Chance}}},
year = {{2015}},
}
@article{5559,
author = {{Schwarzer, Knut and Dammann_, Anna and Schneider, Jan}},
journal = {{Brauwelt International VI}},
pages = {{S. 365--368}},
publisher = {{Fachverlag Hans Carl GmbH}},
title = {{{Testing Pasteurization Units}}},
year = {{2015}},
}
@inproceedings{5560,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann_, Anna}},
location = {{Bremen}},
title = {{{Einsatz eines chemischen Indikators zur exakten Bestimmung der Pasteurisationseinheiten - ein Ersatz für den Count Reduction Test?}}},
year = {{2015}},
}
@inproceedings{5561,
author = {{Broeker, Timo and Blöhse, D. and Ramke, Hans-Günter and Schneider, Jan}},
location = {{Nice (Frankreich)}},
title = {{{How to extend a Distillery into a Lignocellulose Biorefinery}}},
year = {{2015}},
}
@inproceedings{5562,
author = {{Kothe, T. and Wiens, Anton and Kracht, A. and Kaetzel, M. and Rossmann, Sören and Rabenhorst, Jürgen}},
location = {{Nice (Frankreich)}},
title = {{{Characterization and Optimization of the Enzymatic Hydrolysis of Different Citrus Peel (Orange) Qualities.}}},
year = {{2015}},
}
@inproceedings{5563,
author = {{Hoffarth, Marc and Broeker, Timo and Wolff, V. and Mengendoth, C. and Heidkrodt, K. and Schneider, Jan}},
location = {{Nice (Frankreich)}},
title = {{{Synergies between biocatalytic methanation of Power-To-Gas hydrogen with carbon dioxide from alcoholic fermentation}}},
year = {{2015}},
}
@inproceedings{5564,
author = {{Broeker, Timo and Hoffarth, Marc and Oppermann, L. and Wolff, V and Mengedoth, C. and Schneider, Jan}},
location = {{Nice (Frankreich)}},
title = {{{Wet Oxidation of Lignocellulosic Biomasses with Electrolytic produced Active Chlorine}}},
year = {{2015}},
}
@inproceedings{5565,
author = {{Schweizer, K. and Schneider, Jan}},
location = {{Berlin}},
title = {{{Wie groß ist der Beitrag der Aufheiz- und Abkühlzonen einer KZE für die Abtötung der MO oder Muss man die Aufheiz- und Abkühlzonen einer KZE die PE Berechnung einbeziehen? }}},
year = {{2015}},
}
@article{5566,
author = {{Behler, M. and Schulze, Christian and Schneider, Jan}},
journal = {{Brauindustrie 11}},
pages = {{S. 92--98}},
title = {{{Einsatz von Magnetrührwerken in Hefeanzuchtfermentern und deren Einfluss auf die Vitalität und Viabilität von Saccharomyces-Hefen}}},
volume = {{11}},
year = {{2015}},
}
@article{5567,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
journal = {{Chemie-Ingenieur-Technik }},
number = {{7}},
pages = {{S. 1006--1010}},
title = {{{Untersuchungen zur Steigerung der Trocknungsgeschwindigkeit der Gefriertrocknung}}},
volume = {{87}},
year = {{2015}},
}
@misc{6156,
author = {{Müller, Ulrich and Ollesch, K.}},
title = {{{Verfahren und Vorrichtung zum Reinigen eines Mischers}}},
year = {{2015}},
}
@article{6208,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
journal = {{Ingenieur-Technik }},
number = {{7}},
pages = {{1006--1010}},
title = {{{Untersuchungen zur Steigerung der Trocknungsgeschwindigkeit der Gefriertrocknung}}},
volume = {{87}},
year = {{2015}},
}
@misc{12978,
abstract = {{Diet change and fatness are supposed to challenge the immune system of the cow. Therefore, immunological and haematological consequences of adaptation to and continued feeding of a high-energy diet were studied in eight non-pregnant, non-lactating Holstein cows over 16 weeks. Blood haptoglobin concentration remained unaltered, suggesting that an acute phase reaction was not induced. Stimulation ability of peripheral blood mononuclear cells and stimulated oxidative burst capacity of granulocytes increased significantly in the course of the experiment after an initial drop. While total leucocyte counts increased, the proportion of granulocytes increased and that of lymphocytes decreased at the same time as the ratio of CD4+/CD8+ lymphocytes did. Capability of rumen microbes to detoxify the immune-modulating mycotoxin deoxynivalenol (DON) was not compromised as indicated by the exclusive presence of de-DON as the detoxified DON metabolite in blood. In conclusion, both diet change and prolonged positive energy balance influenced the bovine immune system.}},
author = {{Dänicke, Sven and Meyer, Ulrich and Winkler, Janine and Ulrich, Sebastian and Frahm, Jana and Kersten, Susanne and Valenta, Hana and Rehage, Jürgen and Häussler, Susanne and Sauerwein, Helga and Locher, Lena}},
booktitle = {{Archives of Animal Nutrition}},
issn = {{1477-2817}},
keywords = {{Dairy cowsdeoxynivalenol, energy consumption, functional responses, haematology, leucocytes, mycotoxins, zearalenone}},
number = {{1}},
pages = {{1--16}},
publisher = {{Taylor & Francis}},
title = {{{Haematological and immunological adaptations of non-pregnant, non-lactating dairy cows to a high-energetic diet containing mycotoxins}}},
doi = {{10.1080/1745039x.2015.1117561}},
volume = {{70}},
year = {{2015}},
}
@inproceedings{6451,
author = {{Hüttemann, N. and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Bernburg}},
title = {{{Untersuchung zur Zerstörung der Ätherisch Ölzellen bei der Sattdampfbehandlung von Pflanzenmaterial}}},
year = {{2014}},
}
@inproceedings{6452,
author = {{Hüttemann, N. and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Freising}},
title = {{{Untersuchung zur Zerstörung der Ätherisch Ölzellen bei der Sattdampfbehandlung von Pflanzenmaterial}}},
year = {{2014}},
}
@inproceedings{6453,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann_, Anna and Müller, Ulrich}},
location = {{Ghent (Belgium)}},
title = {{{Effect of the residence time distribution in flash pasteurizers on the thermal death of microorganism under consideration of the heating and cooling sections}}},
year = {{2014}},
}
@inproceedings{6454,
author = {{Müller, Ulrich}},
location = {{Rodgau}},
title = {{{Entkeimungsverfahren und biologische Stabilisierung von Lebensmitteln – Behandlungsverfahren für fluide und feste Substanzen aus Sicht eines Lebensmittelverfahrenstechnikers}}},
year = {{2014}},
}
@misc{12145,
author = {{Hüttner, C. and Kutz, Gerd and Dietrich, S. }},
location = {{Graz (Österreich)}},
title = {{{PAT in High-Shear Granulation Processes using In-line Particle Size Measurements}}},
year = {{2014}},
}
@misc{12146,
author = {{Hüttner , C. and Türken, B. and Kutz, Gerd and Dietrich, Stefan}},
location = {{Lissabon (Portugal)}},
title = {{{Real time process control during wet granulation in a high-shear mixer using Spatial Filter Velocimetry - Influence of different formulations }}},
year = {{2014}},
}
@misc{12157,
author = {{Lewandowski, E. and Kamke, Dominic and Kutz, Gerd and Dietrich, S.}},
location = {{Lissabon (Portugal)}},
title = {{{Real time particle size measurement during high-shear melt granulation}}},
year = {{2014}},
}
@misc{2363,
author = {{Becker, Barbara}},
booktitle = {{Brauwelt International}},
number = {{5}},
pages = {{252--256}},
title = {{{useful for beverage spoilage microoganism}}},
year = {{2014}},
}
@misc{2388,
author = {{Hahne, T. and Schwarze, B. and Kramer, M. and Frahm, Björn}},
booktitle = {{Journal of Algal Biomass Utilization}},
issn = {{2229-6905}},
number = {{2}},
pages = {{66--73}},
publisher = {{PHYCO SPECTRUM}},
title = {{{Disposable algae cultivation for high-value products using all around LED-illumination directly on the bags}}},
volume = {{5}},
year = {{2014}},
}
@article{2402,
author = {{Schneider, Jan and Broeker, Timo and Steffens, Marco and Schulze, Christian}},
journal = {{Getränkeherstellung Deutschland}},
number = {{1}},
pages = {{18 -- 19}},
title = {{{Getränke aus fermentierter und nicht fermentierter Bierwürze}}},
year = {{2014}},
}
@article{2403,
author = {{Becker, Barbara and Becker, Verena and Nerenz, Heiko and Schrader, Andreas}},
issn = {{0942-7694}},
journal = {{SOFW-Journal : Home & personal care ingredients & formulations; Deutsche Ausgabe}},
number = {{5}},
pages = {{26 -- 27, 30}},
publisher = {{Verl. für Chemische Industrie, Ziolkowsky}},
title = {{{Einsatz der Durchflusszytometrie zum Nachweis der antimikrobiellen Wirkung von Phytoalexinen und Pflanzenextrakten}}},
volume = {{140}},
year = {{2014}},
}
@article{2440,
author = {{Upmann, Matthias and Stiebing, Achim and Hillgärtner, Karin}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{1}},
pages = {{28--33}},
publisher = {{Dt. Fachverl.}},
title = {{{Geräuchertes liegt weiterhin im Trend - DLG-Qualitätsprüfung 2012 – Rohwürste und Rohpökelwaren }}},
volume = {{93}},
year = {{2014}},
}
@article{2441,
author = {{Upmann, Matthias and Stiebing, Achim and Hillgärtner, Karin}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{12}},
pages = {{50--54}},
publisher = {{Dt. Fachverl.}},
title = {{{Anteil SB-verpackter Erzeugnisse gestiegen - DLG-Qualitätsprüfung – Rohwürste und Rohpökelwaren im Ausland stark}}},
volume = {{93}},
year = {{2014}},
}
@article{2548,
author = {{Stiebing, Achim and Weyland, Gerd}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft}},
number = {{12}},
pages = {{46 -- 49}},
title = {{{Was ist erlaubt, was verboten? - 9. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost – Teil 3}}},
volume = {{93}},
year = {{2014}},
}
@article{2550,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{12}},
pages = {{61 -- 63}},
title = {{{Was ist erlaubt, was verboten? : 1. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2005 - Teil 2}}},
volume = {{85}},
year = {{2014}},
}
@inbook{2589,
author = {{Upmann, Matthias and Stender, Jörg and Trilling, J.}},
booktitle = {{Encyclopedia of meat sciences}},
pages = {{159--167}},
publisher = {{Elsevier}},
title = {{{Quality management: Abattoirs and processing plants}}},
volume = {{3}},
year = {{2014}},
}
@misc{2590,
author = {{Upmann, Matthias and Stephan, Rainer}},
booktitle = {{Encyclopedia of meat sciences}},
pages = {{145--151}},
publisher = {{Elsevier}},
title = {{{Laboratory accreditation}}},
year = {{2014}},
}
@inproceedings{2591,
author = {{Upmann, Matthias}},
location = {{Erfurt}},
title = {{{Dekontamination von Schlachttierkörpern durch Milchsäure - eine Übersicht}}},
year = {{2014}},
}
@inproceedings{2592,
author = {{Upmann, Matthias and Köhne, T. and Langen, M.}},
location = {{Berlin}},
title = {{{Aspikerzeugnisse: Gewichtsverlust der Einlagen bei der Herstellung und Lagerung}}},
year = {{2014}},
}
@inproceedings{2593,
author = {{Upmann, Matthias and Bleischwitz, L. and Fritzsche, Lutz and Hartmann, V. and Knedlik, R. and Peter, M. and Schneiders, S. and Schöneis, R. and Röser, Anja}},
location = {{Garmisch-Partenkirchen}},
title = {{{Welchen Schneidsatz braucht der Wolf? Muskelfaserzerstörung in Hackfleischpatties}}},
year = {{2014}},
}
@inproceedings{2594,
author = {{Upmann, Matthias}},
location = {{Garmisch-Partenkirchen}},
title = {{{Kriterienkatalog zur mikroskopischen Bewertung von Muskelfaserstruktur-Veränderungen. Workshop "Lebensmittelhistologie"}}},
year = {{2014}},
}
@inproceedings{2595,
author = {{Upmann, Matthias and Lade, P.}},
location = {{Lemgo}},
title = {{{Knochenpartikel in Brühwurst. Einfluss von Rohmaterial und Herstellungstechnologie}}},
year = {{2014}},
}
@inproceedings{2596,
author = {{Upmann, Matthias}},
location = {{Frankfurt}},
title = {{{Tierkörpermerkmale als Risikofaktor für Ebergeruch}}},
year = {{2014}},
}
@inbook{2632,
author = {{Kutz, Gerd and Pohlmann, Döthe and Wiebe, Viktor}},
booktitle = {{Apothekenrezeptur und -defektur: Herstellung von Arzneimitteln und Körperpflegemitteln }},
editor = {{Thoma, Karl and Daniels, Rolf}},
isbn = {{978-3-7692-5881-3}},
publisher = {{Dt. Apotheker-Verl. }},
title = {{{Haut- und Körperpflegemittel}}},
volume = {{Kapitel 4}},
year = {{2014}},
}
@article{2634,
author = {{Kutz, Gerd and Walger, Tatjana and Feiler, Stefanie and Solot, Philippe}},
issn = {{1434-8942}},
journal = {{Pharma + Food}},
number = {{3}},
pages = {{90 -- 92}},
publisher = {{Hüthig }},
title = {{{Den Designspace definieren : Bessere Prozesskenntnisse erleichtern die Validierung}}},
volume = {{12}},
year = {{2014}},
}
@article{2636,
author = {{Kutz, Gerd and Felbusch, Natalja and Feiler, Stefanie and Solot, Philippe}},
issn = {{2198-0691 }},
journal = {{Prozesstechnik : das Fachmagazin für die gesamte Prozessindustrie ; Chemie, Pharma, Food}},
number = {{8}},
pages = {{54 -- 55}},
publisher = {{Fachwelt-Verl. }},
title = {{{Schnelle Identifikation wichtiger Parameter mittels Versuchsplanung : Zwei auf einen Streich}}},
volume = {{43}},
year = {{2014}},
}
@inproceedings{4403,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Emulsionen im Spiegel von ICH- und PIC/S-Empfehlungen}}},
year = {{2014}},
}
@inproceedings{4404,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Rohstoffe und Formulierungsstrategien}}},
year = {{2014}},
}
@inproceedings{4405,
author = {{Kutz, Gerd}},
location = {{Nürnberg }},
title = {{{Sterilisierung und Desinfektion im Life Science Bereich}}},
year = {{2014}},
}
@inproceedings{4434,
author = {{Kutz, Gerd}},
keywords = {{Scientific lecture and workshop}},
location = {{Paris (Frankreich)}},
title = {{{Formulation for better efficacy}}},
year = {{2014}},
}
@inproceedings{4462,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{APV basics}}},
year = {{2014}},
}
@misc{2878,
abstract = {{Ein Bioreaktor mit einem Disposable Bag, der einen von einer Wandung (1) begrenzten Reaktorraum (2) aufweist, ist als Photo-Bioreaktor ausgelegt, bei dem in unmittelbarer Nachbarschaft der Wandung (1) des Disposable Bags Lichtquellen (LED-Streifen 6) angeordnet sind. }},
author = {{Frahm, Björn and Meier, Uwe}},
pages = {{9}},
title = {{{Beleuchtung von disposable Bioreaktoren}}},
year = {{2014}},
}
@misc{2984,
author = {{Drews, F. and Drews, G. and Folz, C. and Platz, G. and Gassenmeier, Thomas and Kramer, M. and Hundeiker, C. and Schwarze, B. and Frahm, Björn}},
location = {{Köthen, Germany}},
title = {{{Herstellung von Paramylon mit Euglena gracilis im disposable Bag mit LED-Beleuchtung direkt auf dessen Oberfläche}}},
year = {{2014}},
}
@article{3399,
author = {{Dammann, Anna and Schwarzer, Knut and Neubauer, Peter and Schneider, Jan}},
issn = {{0723-1520}},
journal = {{BrewingScience}},
number = {{7}},
pages = {{101--107}},
publisher = {{Carl}},
title = {{{Effect of Residence Time Distribution in Flash Pasteurizers on the Thermal Death of Microorganisms}}},
volume = {{67}},
year = {{2014}},
}
@article{3400,
author = {{Schneider, Jan and Dammann_, Anna and Schwarzer, Knut}},
issn = {{0724-696X }},
journal = {{Brauwelt : Wochenzeitschrift für das Getränkewesen }},
number = {{27/28}},
pages = {{821--824}},
publisher = {{Carl}},
title = {{{Prüfung von Pasteurisationsanlagen}}},
year = {{2014}},
}
@inproceedings{5442,
author = {{Broeker, Timo and Hoffarth, M. and Schneider, Jan and Heikrodt, Klaus}},
booktitle = {{12. Internationaler Fachkongress für Biokraftstoffe "Fuels of the Future" (Vortrag und Tagungsbandbeitrag), Berlin, 20.01.2014}},
location = {{Berlin}},
title = {{{BioCo2nvert - Synergies of P2G and alcoholic CO2 for the efficient production of methan and bioethanol}}},
year = {{2014}},
}
@inproceedings{5448,
author = {{Lüttke Föller, A. and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich}},
booktitle = {{24. Bernburger Winterseminar Arznei- und Gewürzpflanzen : 18.02. - 19.02.2014 ; Tagungsbroschüre }},
editor = {{Hoppe, Bernd}},
location = {{Bernburg}},
publisher = {{Verein für Arznei- und Gewürzpflanzen Saluplanta }},
title = {{{Einfluss der Evakuierungsgeschwindigkeit auf die Majoranölverluste bei der Sattdampfbehandlung}}},
year = {{2014}},
}
@inproceedings{5449,
author = {{Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich and Schneider, Jan}},
location = {{Freising}},
title = {{{Simulation zur Flaschen-Vollpasteurisation - Simulation zur Flaschen-Vollpasteurisation}}},
year = {{2014}},
}
@inproceedings{5450,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R:}},
location = {{Freising}},
title = {{{Wärmeübergang bei der dynamischen Gefriertrocknung in Feststoffmischern}}},
year = {{2014}},
}
@inproceedings{5451,
author = {{Hüttemann, N. and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich}},
booktitle = {{ProcessNet-Fachgruppe Lebensmittelverfahrenstechnik, Freising, 26.-28.02.2014}},
location = {{Freising}},
title = {{{Untersuchung zur Zerstörung der ätherischen Ölzellen bei der Sattdampfbehandlung von Planzenmaterial}}},
year = {{2014}},
}
@inproceedings{5452,
author = {{Lüttke Föller, A. and Schwarzer, Knut and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Freising}},
title = {{{Einfluss der Evakuierungsgeschwindigkeit auf die Majoranölverluste bei der Sattdampfbehandlung}}},
year = {{2014}},
}
@inproceedings{5453,
author = {{Cornu, Jesahel and Lüttke Föller, A. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Frankfurt-Rodgau}},
title = {{{Wirksame Kondensatfilmdicke bei der mechanischen Sattdampfentkeimung von pflanzlichen Materialien}}},
year = {{2014}},
}
@inproceedings{5454,
author = {{Stiebing, Achim}},
booktitle = {{ Fortbildungsseminar des Bundesverbandes der Deutschen Fleischwarenindustrie (BVDF), Rheinhardsbrunn, 15./16.03.2013 und 13./14.03.2014}},
location = {{Rheinhardsbrunn}},
title = {{{Technologien zur Herstellung von Kochschinken und Kochwurst. Neue Zutaten und Zusatzstoffe, Chancen, Grenzen und Technologien. Betriebliche QS-Konzepte für die Roh- und Brühwurstherstellung}}},
year = {{2014}},
}
@inproceedings{5455,
author = {{Broeker, Timo and Blöhse, D. and Bittner, J. and Ramke, Hans-Günter and Schneider, Jan}},
booktitle = {{10th European Bioethanol and Bioconversion Technology Meeting, Detmold, 08.04.2014}},
location = {{Detmold}},
title = {{{How to extend a distillery into a lignocellulose biorefinery – Material - & Energy Flow Management of Bioethanol, Biogas & HTC Biochar}}},
year = {{2014}},
}
@inproceedings{5456,
author = {{Stiebing, Achim}},
booktitle = {{Rotary Lemgo, 14.04.2014}},
location = {{Lemgo}},
title = {{{Fleisch und Fleischerzeugnisse im Kreuzfeuer der Kritik}}},
year = {{2014}},
}
@inproceedings{5458,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann, Anna and Müller, Ulrich}},
booktitle = {{11th International Trends in Brewing, Ghent (Belgium), April 13th-17th 2014}},
location = {{Ghent (Belgium)}},
title = {{{Effect of residence time distribution in flash pasteurizers on the thermal death oEffect of the residence time distribution in flash pasteurizers on the thermal death of microorganism under consideration of the heating and cooling sectionsf microorganisms}}},
year = {{2014}},
}
@article{5460,
author = {{Zapp, Jürgen and Kothe, Achim and Münstermann, J.}},
issn = {{0344-5208 }},
journal = {{LABO – Fit for Lab}},
number = {{1-2}},
pages = {{12--14}},
title = {{{Welche Stoffe in harten Getränken?}}},
year = {{2014}},
}
@article{5462,
author = {{Damman, Anna and Schwarzer, Knut and Müller, Ulrich and Schneider, Jan}},
issn = {{1521-3811}},
journal = {{Lebensmittelchemie : Zeitschrift d. Lebensmittelchemischen Gesellschaft, Fachgruppe in der Gesellschaft Deutscher Chemiker}},
number = {{6}},
pages = {{151}},
publisher = {{Wiley-VCH}},
title = {{{Backverhalten und Sensorik eines Färberdistelblüteneytraktes am Beispiel Rührkuchen}}},
doi = {{10.1002/lemi.201490056}},
volume = {{68}},
year = {{2014}},
}
@article{5477,
author = {{Münstermann, J. and Kothe, Achim and Zapp, Jürgen}},
issn = {{1521-3811}},
journal = {{Lebensmittelchemie : Zeitschrift d. Lebensmittelchemischen Gesellschaft, Fachgruppe in der Gesellschaft Deutscher Chemiker}},
number = {{6}},
pages = {{152}},
publisher = {{Wiley-VCH}},
title = {{{Analytik von Farbstoffen aus den Blüten der Färberdistel Carthamus tinctorius}}},
doi = {{10.1002/lemi.201490056}},
volume = {{68}},
year = {{2014}},
}
@inproceedings{5478,
author = {{Broeker, Timo and Barten, G.}},
booktitle = {{EnergieAgentur.NRW 3, Wuppertal (2014)}},
location = {{Wuppertal}},
title = {{{Biokraftstoffe aus Rest- und Abfallstoffen? Pro & Contra; Innovation & Energie}}},
year = {{2014}},
}
@article{5479,
author = {{Woest, H. and Cöllü, I. and Dammann, Anna and Schwarzer, Knut and Schneider, Jan}},
issn = {{0179-2466}},
journal = {{Brauerei-Forum : Fachzeitschrift für Brauereien und Mälzereien, Getränkeindustrie und deren Partner }},
number = {{8}},
publisher = {{Westkreuz-Verl. }},
title = {{{Forschungsprojekt zur nachhaltigen und schonenden Getränkepasteurisation abgeschlossen}}},
year = {{2014}},
}
@article{5480,
author = {{Schneider, Jan}},
issn = {{0936-4129 }},
journal = {{Getränkeherstellung Deutschland : Informationen für die Wirtschaft }},
publisher = {{Kuhn}},
title = {{{Kundennähe – Wieviel Nähe darf es denn sein? }}},
year = {{2014}},
}
@inproceedings{5481,
author = {{Stiebing, Achim}},
booktitle = {{Museumsrunde Detmold, 01.06.2014}},
location = {{Detmold}},
title = {{{Ebermast - ... Ein neuer Weg?}}},
year = {{2014}},
}
@misc{5482,
abstract = {{The invention relates to a method for producing enriched peptide fractions from protein-containing raw materials, in which protein hydrolysates are separated using chromatography, according to the physiochemical properties thereof, by means of stationary phases with an aqueous solution as an elution agent. }},
author = {{Danneel, Hans-Jürgen}},
title = {{{Method For Producing Peptide Fractions And Use Thereof; Offenlegungsschrift}}},
year = {{2014}},
}
@inproceedings{5483,
author = {{Stiebing, Achim}},
booktitle = {{Zoetis Seminar, Potsdam, 26.06.2014}},
location = {{Potsdam}},
title = {{{Impfung gegen Ebergeruch - Verarbeitungseigenschaften}}},
year = {{2014}},
}
@inproceedings{5484,
author = {{Bernert, Till and Zapp, Jürgen}},
booktitle = {{41. Deutscher Lebensmittelchemikertag, Münster, 10.-12.09.2014}},
location = {{Münster}},
title = {{{Polyphenolgehalte in alten und neuen Apfelsorten in Bezug auf allergene Wirkungen}}},
year = {{2014}},
}
@inproceedings{5485,
author = {{Steffens, M. and Schneider, Jan}},
booktitle = {{GDL Kongress Lebensmitteltechnologie 2014, Frankfurt-Rodgau, 16.10-18.10.2014}},
location = {{Frankfurt-Rodgau}},
title = {{{Bindung von Eisen an Caseinphosphopeptide}}},
year = {{2014}},
}
@inproceedings{5486,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
booktitle = {{GDL Kongress Lebensmitteltechnologie 2014, Frankfurt-Rodgau, 16.10-18.10.2014}},
location = {{Frankfurt-Rodgau}},
title = {{{Bestimmung von der Trocknungsgeschwindigkeit und des Wärmeübergangskoeffizienten bei der dynamischen Gefriertrocknung von Starterkulturen in einem Feststoffmischer}}},
year = {{2014}},
}
@inproceedings{5487,
author = {{Müller, Ulrich}},
booktitle = {{GDL Kongress Lebensmitteltechnologie 2014, Frankfurt-Rodgau, 16.10-18.10.2014}},
location = {{Frankfurt-Rodgau}},
title = {{{ Entkeimungsverfahren und biologische Stabilisierung von Lebensmitteln - Behandlungsverfahren für fluide und feste Substanzen aus Sicht eines Lebensmittelverfahrenstechnikers}}},
year = {{2014}},
}
@inproceedings{5488,
author = {{Stiebing, Achim}},
booktitle = {{37. Lemgoer Arbeitstagung Fleisch und Feinkost, 03.11.2014}},
location = {{Lemgo}},
title = {{{Gefrierlagerstabilität von Fleischerzeugnissen - Anforderungen an fleischhaltige TK-Produkte}}},
year = {{2014}},
}
@inproceedings{5489,
author = {{Stiebing, Achim}},
booktitle = {{Fortbildungsseminar des Bundesverbandes der Deutschen Fleischwarenindustrie (BVDF), Rheinhardsbrunn, 16.-17.11.2013 und 15.-16.11.2014}},
location = {{Rheinhardsbrunn}},
title = {{{Technologie der Rohschinkenherstellung - Technologie der Rohwurstherstellung}}},
year = {{2014}},
}
@inproceedings{5490,
author = {{Broeker, Timo and Blöhse, D. and Bittner, J. and Ramke, Hans-Günter and Schneider, Jan}},
booktitle = {{Biokraftstofftagung NRW, Haus Düsse, Landwirtschaftskammer NRW, Bad Sassendorf, 27.11.2014}},
location = {{Bad Sassendorf}},
title = {{{Erweiterung einer Brennerei zu einer Lignocellulose-Bioraffinerie - Stoff- und Energiestrom Management für Bioethanol, Biogas und HTC-Biokohle}}},
year = {{2014}},
}
@misc{12979,
abstract = {{Physiological consequences of adaptation to and continued feeding of a high-energetic diet were studied in eight non-pregnant, non-lactating dairy Holstein cows over a period of 16 weeks. The first six weeks served as an adaptation period from the low energetic straw-based diet (3.8 MJ NEL/kg DM) to the high-energetic ration (7.5 MJ NEL/kg DM). Intake of dry matter (DM) increased with dietary energy concentration from 9 to 20 kg/d up to week 9 to 12 and decreased thereafter. The initial live weight (LW) of 550 ± 60 kg was increased linearly and corresponded to an average daily LW gain of 2.3 ± 0.3 kg. Energy balance increased approximately nine-fold to a maximum of 114 MJ NEL/d in week 10. Ruminal fermentation pattern was completely changed from an acetate dominating profile to a propionate based one, which was paralleled by a marked increase in the rumen fluid endotoxin concentration. Unlike blood glucose concentration, which increased continuously, that of cholesterol and triglycerides started to increase after an initial stagnation. In conclusion, both ruminal adaptation to a high-energetic diet and the continued feeding of such a diet induced digestive and metabolic adaptations in non-pregnant, non-lactating cows characterised by a progressing positive energy balance.}},
author = {{Dänicke, Sven and Meyer, Ulrich and Winkler, Janine and Schulz, Kirsten and Ulrich, Sebastian and Frahm, Jana and Kersten, Susanne and Rehage, Jürgen and Breves, Gerhard and Häußler, Susanne and Sauerwein, Helga and Locher, Lena}},
booktitle = {{Archives of Animal Nutrition}},
issn = {{1477-2817}},
keywords = {{blood chemistry, dairy cows, endotoxins, energy balance, energy content, rumen fermentation}},
number = {{6}},
pages = {{460--477}},
publisher = {{Taylor & Francis}},
title = {{{Description of a bovine model for studying digestive and metabolic effects of a positive energy balance not biased by lactation or gravidity}}},
doi = {{10.1080/1745039x.2014.973243}},
volume = {{68}},
year = {{2014}},
}
@misc{12984,
abstract = {{Background
Pseudoxanthoma elasticum (PXE) is a rare hereditary disorder characterized by late onset and progressive calcification of elastic fibers in skin, eyes and the cardiovascular system, exemplifying a model for conditions characterized by soft tissue calcification.
Objective
The aim of our study was to characterize cellular inorganic pyrophosphate (PPi) homeostasis in PXE.
Methods
Gene expression of PPi metabolizing enzymes was determined by quantitative real-time PCR after incubation up to 21 days with or without addition of Na2HPO4. Extracellular and cytosolic PPi concentrations were measured by enzyme-linked bioluminescence assay. ALP and ENPP1 activity was determined spectrophotometrically. We further established a human cell culture model suitable for investigating PXE and related disorders without addition of artificial calcification triggers.
Results
Independently of the experimental conditions, PXE fibroblasts revealed a higher degree of matrix calcification. We observed that matrix calcification was associated with altered gene expression of PPi metabolizing enzymes in PXE fibroblasts. In this context, PXE fibroblasts exhibited significantly higher expression of ALP and OPN and reduced mRNA expression and activity of ENPP1. Here, for the first time cytosolic and extracellular PPi levels were shown to be strongly reduced in PXE fibroblasts. We further showed that PPi concentration in bovine and human sera additives had a strong impact on matrix calcification. In a last experimental line, we demonstrated that addition of PPi analogs reduced matrix calcification of PXE fibroblasts most likely by reducing ALP and OPN mRNA expression, restoring ENPP1 activity and subsequently elevating PPi concentrations.
Conclusion
The results of our study along with recent findings point to the essential role of PPi as the central regulatory metabolites preventing matrix calcification in PXE. But what remains to be determined is the underlying molecular mechanism leading to depletion of PPi in PXE. We further suggest that supplementation of PPi analogs might counteract pathological calcification in PXE and related disorders.}},
author = {{Dabisch-Ruthe, Mareike and Kuzaj, Patricia and Götting, Christian and Knabbe, Cornelius and Hendig, Doris}},
booktitle = {{Journal of Dermatological Science}},
issn = {{1873-569X}},
keywords = {{Pseudoxanthoma elasticum, Calcification, Pyrophosphate, Bisphosphonate, ABCC6, Tissue nonspecific alkaline phosphate, Ectonucleotide pyrophosphatase 1}},
number = {{2}},
pages = {{109--120}},
publisher = {{Elsevier }},
title = {{{Pyrophosphates as a major inhibitor of matrix calcification in Pseudoxanthoma elasticum}}},
doi = {{10.1016/j.jdermsci.2014.04.015}},
volume = {{75}},
year = {{2014}},
}
@misc{12985,
abstract = {{Objectives
Pseudoxanthoma elasticum (PXE) is a rare hereditary disorder characterized by progressive calcification and fragmentation of elastic fibers. Because of the great clinical variability between PXE patients the involvement of modifier genes was recently suggested. Therefore, we investigated the association of single nucleotide variants (SNVs) in selected candidate genes known to regulate cellular pyrophosphate metabolism.
Design and methods
We used RLFP analyses to evaluate the distribution of SNVs in alkaline phosphatase (ALP), ectonucleotide pyrophosphatase 1 (ENPP1) and ankylosis (ANKH) in DNA samples from 190 German PXE patients and 190 age- and sex-matched healthy controls. Statistical analyses were performed using Fisher exact test and Bonferroni correction.
Results
The screening revealed three different SNVs in three genes, which were associated with PXE. The SNV c.1190-65C > A (rs1780329, minor allele frequency (MAF) patients: 0.17; controls: 0.11; P = 0.04) in the ALP gene was significantly more frequent in PXE patients. Furthermore, PXE was highly associated with ANKH p.A98A genotype TT (P = 0.0012), although the MAF was not different between patients and controls. After correction for multiple testing according to the Bonferroni method, one SNV in the ENPP1 gene (c.313 + 9G > T, rs7773477) remained significantly associated with PXE with significantly higher MAF values in the patient cohort (MAF: 0.04 vs. 0.00; P = 0.0024) and a high association with PXE susceptibility (OR 27.96).
Conclusion
Polymorphisms in ALP, ENPP1 and ANKH are important genetic risk factors contributing to PXE.}},
author = {{Dabisch-Ruthe, Mareike and Brock, Alexander and Kuzaj, Patricia and Charbel Issa, Peter and Szliska, Christiane and Knabbe, Cornelius and Hendig, Doris}},
booktitle = {{Clinical Biochemistry}},
issn = {{1873-2933}},
keywords = {{Pseudoxanthoma elasticum, Calcification, Tissue nonspecific alkaline phosphatase, Ectonucleotide pyrophosphatase 1, Ankylosis}},
number = {{15}},
pages = {{60--67}},
publisher = {{Elsevier}},
title = {{{Variants in genes encoding pyrophosphate metabolizing enzymes are associated with Pseudoxanthoma elasticum}}},
doi = {{10.1016/j.clinbiochem.2014.07.003}},
volume = {{47}},
year = {{2014}},
}
@misc{12986,
abstract = {{Background
Dysregulations in cholesterol and lipid metabolism have been linked to human diseases like hypercholesterolemia, atherosclerosis or the metabolic syndrome. Many ABC transporters are involved in trafficking of metabolites derived from these pathways. Pseudoxanthoma elasticum (PXE), an autosomal-recessive disease caused by ABCC6 mutations, is characterized by atherogenesis and soft tissue calcification.
Methods
In this study we investigated the regulation of cholesterol biosynthesis in human dermal fibroblasts from PXE patients and healthy controls.
Results
Gene expression analysis of 84 targets indicated dysregulations in cholesterol metabolism in PXE fibroblasts. Transcript levels of ABCC6 were strongly increased in lipoprotein-deficient serum (LPDS) and under serum starvation in healthy controls. For the first time, increased HMG CoA reductase activities were found in PXE fibroblasts. We further observed strongly elevated transcript and protein levels for the proprotein convertase subtilisin/kexin type 9 (PCSK9), as well as a significant reduction in APOE mRNA expression in PXE.
Conclusion
Increased cholesterol biosynthesis, elevated PCSK9 levels and reduced APOE mRNA expression newly found in PXE fibroblasts could enforce atherogenesis and cardiovascular risk in PXE patients. Moreover, the increase in ABCC6 expression accompanied by the induction of cholesterol biosynthesis supposes a functional role for ABCC6 in human lipoprotein and cholesterol homeostasis.}},
author = {{Kuzaj, Patricia and Kuhn, Joachim and Dabisch-Ruthe, Mareike and Faust, Isabel and Götting, Christian and Knabbe, Cornelius and Hendig, Doris}},
booktitle = {{Lipids in Health and Disease}},
issn = {{1476-511X}},
keywords = {{Pseudoxanthoma elasticum, ABC transporter, ABCC6, Cholesterol biosynthesis, Atherosclerosis, HMG CoA reductase, SREBP2, PCSK9, LDLR, APOE}},
number = {{1}},
publisher = {{Biomed Central }},
title = {{{ABCC6- a new player in cellular cholesterol and lipoprotein metabolism?}}},
doi = {{10.1186/1476-511x-13-118}},
volume = {{13}},
year = {{2014}},
}
@misc{12987,
abstract = {{Mutations in the ABC transporter ABCC6 were recently identified as cause of Pseudoxanthoma elasticum (PXE), a rare genetic disorder characterized by progressive mineralization of elastic fibers. We used an untargeted metabolic approach to identify biochemical differences between human dermal fibroblasts from healthy controls and PXE patients in an attempt to find a link between ABCC6 deficiency, cellular metabolic alterations and disease pathogenesis. 358 compounds were identified by mass spectrometry covering lipids, amino acids, peptides, carbohydrates, nucleotides, vitamins and cofactors, xenobiotics and energy metabolites. We found substantial differences in glycerophospholipid composition, leucine dipeptides, and polypeptides as well as alterations in pantothenate and guanine metabolism to be significantly associated with PXE pathogenesis. These findings can be linked to extracellular matrix remodeling and increased oxidative stress, which reflect characteristic hallmarks of PXE. Our study could facilitate a better understanding of biochemical pathways involved in soft tissue mineralization.}},
author = {{Kuzaj, Patricia and Kuhn, Joachim and Michalek, Ryan D. and Karoly, Edward D. and Faust, Isabel and Dabisch-Ruthe, Mareike and Knabbe, Cornelius and Hendig, Doris}},
booktitle = {{PLOS ONE / Public Library of Science }},
issn = {{1932-6203}},
number = {{9}},
publisher = {{Public Library of Science (PLoS)}},
title = {{{Large-Scaled Metabolic Profiling of Human Dermal Fibroblasts Derived from Pseudoxanthoma Elasticum Patients and Healthy Controls}}},
doi = {{10.1371/journal.pone.0108336}},
volume = {{9}},
year = {{2014}},
}
@inproceedings{6449,
author = {{Müller, Ulrich}},
title = {{{Mikrobiologie-Datenbank Lemgo – D- und z-Werte Lebensmittel-relevanter Mikroorganismen oder ‚Die Lemgo D- and z-value Database for Food‘ (LDzBase)}}},
year = {{2013}},
}
@inbook{2394,
abstract = {{For the production of biopharmaceuticals a seed train is required to generate an adequate number of cells for inoculation of the production bioreactor. This seed train is time- and cost-intensive but offers potential for optimization. A method and a protocol are described for the seed train mapping, directed modeling without major effort, and its optimization regarding selected optimization criteria such as optimal points in time for cell passaging. Furthermore, the method can also be applied for the set-up of a new seed train, for example for a new cell line. Although the chapter is directed towards suspension cell lines, the method is also generally applicable, e.g. for adherent cell lines.}},
author = {{Frahm, Björn}},
booktitle = {{Animal Cell Biotechnology}},
isbn = {{9781627037327}},
issn = {{1064-3745}},
keywords = {{Seed train Optimization Modeling Prediction Space-Time-Yield (STY) Systems approach Bioinformatics Computational biotechnology Suspension Production}},
pages = {{355--367}},
publisher = {{Humana Press}},
title = {{{Seed Train Optimization for Cell Culture}}},
doi = {{10.1007/978-1-62703-733-4_22}},
volume = {{1104}},
year = {{2013}},
}
@article{2544,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{65 -- 69}},
title = {{{Was ist erlaubt, was verboten? : 8. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 1}}},
volume = {{92}},
year = {{2013}},
}
@article{2546,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{61 -- 62}},
title = {{{Was ist erlaubt, was verboten? : 8. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 2}}},
volume = {{92}},
year = {{2013}},
}
@article{2580,
author = {{Klein, G. and Rüben, C. and Upmann, Matthias}},
journal = {{Current Mibrobiology }},
pages = {{200--208}},
title = {{{Antimicrobial activity of essential oil components against important food spoilage microorganisms}}},
volume = {{67}},
year = {{2013}},
}
@article{2581,
author = {{Sofos, J. and Bolton, D. and Koutsoumanis, K. and Upmann, Matthias and Petracci, M. and Michalski, M. and Broglia, A. and Barizzone, F.}},
journal = {{EFSA Journal}},
number = {{3137}},
pages = {{1--78}},
title = {{{Scientific Opinion on the public health risks related to mechanically separated meat (MSM) derived from poultry and swine}}},
volume = {{11(3)}},
year = {{2013}},
}
@inproceedings{2582,
author = {{Broglia, A. and Hugas, M. and Bolton, D. and Koutsoumanis, K. and Michalski, M. and Petracci, M. and Upmann, Matthias and Sofos, J.}},
location = {{Bergamo (Italien)}},
title = {{{Mechanically separated meat (MSM): EFSA assessment on public health risks and parameters for classification}}},
year = {{2013}},
}
@inproceedings{2583,
author = {{Upmann, Matthias}},
location = {{Lemgo}},
title = {{{Histologische Beurteilung von Kochpökelwaren}}},
year = {{2013}},
}
@inproceedings{2584,
author = {{Upmann, Matthias and Hölscher, Maike and Kelliger, H. and Müller, T. and Stiebing, Achim}},
location = {{Lemgo}},
title = {{{Projekt 3: EtNaFleisch- Innovationsförderung für die Food-Branche - Erfahrungen und Potentiale}}},
year = {{2013}},
}
@inproceedings{2585,
author = {{Upmann, Matthias and Tölke, M. and Röser, Anja}},
location = {{Garmisch-Partenkirchen}},
title = {{{Semiquantitative Bestimmung verschiedener Stärkearten mit Hilfe der histologischen Untersuchung}}},
year = {{2013}},
}
@article{2586,
author = {{Grünewald, T. and Gerhardt, T. and Upmann, Matthias and Hildebrandt, G.}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{87--91}},
title = {{{Gewebliche Beschaffenheit von Kochpökelwaren. ALTS-Laborvergleichsuntersuchung zur histologischen Quantifizierung von Strukturzerstörungen}}},
volume = {{93}},
year = {{2013}},
}
@inproceedings{2587,
author = {{Upmann, Matthias}},
location = {{Hagen}},
title = {{{Separatorenfleisch}}},
year = {{2013}},
}
@inproceedings{2588,
author = {{Upmann, Matthias}},
location = {{Lemgo}},
title = {{{Separatorenfleisch. Möglichkeiten und Grenzen des Nachweises unterschiedlicher Qualitäten}}},
year = {{2013}},
}
@article{2669,
author = {{Kutz, Gerd and Kamke, Dominik}},
issn = {{1616-7074}},
journal = {{Die pharmazeutische Industrie : pharmind ; europharm ; Veröffentlichungen über sämtliche Aspekte der Herstellung und des Vertriebes pharmazeutischer Erzeugnisse ; Forum der Pharma-Industrie für alle Themen der Pharma-, Gesundheits- und Sozialpolitik sowie des Arzneimittelwesens im Umfeld der Marktbeteiligten ; Mitteilungsorgan der Verbände der Pharma-Industrie in Deutschland, Österreich und in der Schweiz}},
number = {{9}},
pages = {{1510 -- 1518}},
publisher = {{Editio-Cantor-Verl. für Medizin und Naturwiss. }},
title = {{{Grundlagen der Sterilfiltration in der pharmazeutischen Industrie}}},
volume = {{75}},
year = {{2013}},
}
@misc{2817,
author = {{Hernández Rodriguez, Tanja and Pörtner, Ralf and Frahm, Björn}},
booktitle = {{BMC proceedings / BioMed Central }},
issn = {{1753-6561}},
publisher = {{BioMed Central }},
title = {{{Seed train optimization for suspension cell culture}}},
doi = {{10.1186/1753-6561-7-s6-p9}},
volume = {{7}},
year = {{2013}},
}
@misc{2818,
author = {{Kern, Simon and Platas, Oscar and Schaletzky, Martin and Sandig, Volker and Frahm, Björn and Pörtner, Ralf}},
booktitle = {{BMC proceedings / BioMed Central }},
issn = {{1753-6561}},
publisher = {{BioMed Central}},
title = {{{Model-based design of the first steps of a seed train for cell culture processes}}},
doi = {{10.1186/1753-6561-7-s6-p11}},
volume = {{7}},
year = {{2013}},
}
@misc{2980,
author = {{Kern, S. and Platas, O. and Schaletzky, M. and Sandig, V. and Frahm, Björn and Pörtner, R.}},
location = {{Bad Wildungen, Germany}},
title = {{{Modellgestützte Auslegung der ersten Schritte eines Seed-Trains für Zellkulturprozesse}}},
year = {{2013}},
}
@misc{2981,
author = {{Kern, S. and Platas, O. and Schaletzky, M. and Sandig, V. and Frahm, Björn and Pörtner, R.}},
location = {{Lille, France}},
title = {{{Model-based design of the first steps of a seed train for cell culture processes}}},
year = {{2013}},
}
@misc{2982,
author = {{Hahne, T. and Schwarze, B. and Moschinski, J. and Kuttig, A. and Kramer, M. and Frahm, Björn}},
location = {{Hamburg, Germany}},
title = {{{Disposable Algenkultivierung für hochpreisige Produkte mittels LED-Rundumbeleuchtung direkt auf den Bags}}},
year = {{2013}},
}
@misc{2983,
author = {{Hernández Rodriguez, Tanja and Pörtner, R. and Frahm, Björn}},
location = {{Lille, France}},
title = {{{Seed train optimization for suspension cell culture}}},
year = {{2013}},
}
@misc{3411,
abstract = {{Diese Richtlinie gibt eine Handlungsanleitung für Planung, Errichtung, Abnahme und Betrieb von Anlagen zur hygienisch sicheren Verarbeitung und für die aseptische Abfüllung von mikrobiologisch sensiblen Getränken und Milchmischgetränken, ohne den Zusatz von Konservierungsmitteln und Kaltentkeimungsmitteln sowie ohne Maßnahmen zur Keiminaktivierung, z.B. die Heißabfüllung oder Tunnelpasteurisation, nach dem Verschließen des Gebindes. Die Richtlinie gilt für aseptische Abfüllanlagen und deren Peripherie, die kommerzielle sterile Getränke und Milchmischgetränke rekontaminationsfrei in vorentkeimte bzw. in der Anlage keimfrei produzierte Packmittel einfüllen und verschließen. Des Weiteren gilt diese Richtlinie für alle zugeordneten Maschinen und Aggregate sowie das Anlagenumfeld. Aseptische Abfüllanlagen der pharmazeutischen Industrie werden nicht behandelt, da die Begrifflichkeiten und Anforderungen von denen der Nahrungsmittel- und Getränkeindustrie abweichen}},
author = {{Schneider, Jan}},
pages = {{77}},
title = {{{Hygieneanforderungen an die Herstellung und aseptische Abfüllung von Getränken - Grundlagen und Auslegungskriterien}}},
year = {{2013}},
}
@inproceedings{3629,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Filterintegritätstests}}},
year = {{2013}},
}
@inproceedings{3630,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Sterilfiltration}}},
year = {{2013}},
}
@inproceedings{6179,
author = {{Müller, Ulrich}},
location = {{Trier}},
title = {{{Wasser – der kalte Entzug – Dynamische Gefriertrocknung}}},
year = {{2013}},
}
@inbook{10214,
abstract = {{For the production of biopharmaceuticals a seed train is required to generate an adequate number of cells for inoculation of the production bioreactor. This seed train is time- and cost-intensive but offers potential for optimization. A method and a protocol are described for the seed train mapping, directed modeling without major effort, and its optimization regarding selected optimization criteria such as optimal points in time for cell passaging. Furthermore, the method can also be applied for the set-up of a new seed train, for example for a new cell line. Although the chapter is directed towards suspension cell lines, the method is also generally applicable, e.g. for adherent cell lines.}},
author = {{Frahm, Björn}},
booktitle = {{Animal Cell Biotechnology - Methods and Protocols}},
editor = {{Pörtner, Ralf}},
isbn = {{978-1-62703-732-7}},
issn = {{1940-6029}},
keywords = {{Seed train, Optimization, Modeling, Prediction, Space-Time-Yield (STY), Systems approach, Bioinformatics, Computational biotechnology, Suspension, Production}},
pages = {{355–367}},
publisher = {{Humana Press}},
title = {{{Seed Train Optimization for Cell Culture}}},
doi = {{10.1007/978-1-62703-733-4_22}},
volume = {{1104}},
year = {{2013}},
}
@inproceedings{5380,
author = {{Stiebing, Achim}},
location = {{Lemgo}},
title = {{{Kochpökelwaren – Technologie und Beurteilungskonzepte}}},
year = {{2013}},
}
@inproceedings{5381,
author = {{Müller, Ulrich}},
keywords = {{Vortrag}},
location = {{Hochschule Trier}},
title = {{{Wasser - der kalte Entzug - Dynamische Gefriertrocknung}}},
year = {{2013}},
}
@inproceedings{5382,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann_, Anna and Müller, Ulrich}},
location = {{Luxembourg (Lux)}},
title = {{{Time-Temperature Integrator for the Flash Pasteurisation}}},
year = {{2013}},
}
@inproceedings{5383,
author = {{Schwarzer, Knut and Dammann_, Anna and Müller, Ulrich and Schneider, Jan}},
location = {{Luxembourg (Lux)}},
title = {{{Critical view on the calculation of pasteurization units in beer}}},
year = {{2013}},
}
@article{5384,
author = {{Bernert, Till and Zapp, Jürgen}},
issn = {{1521-3811}},
journal = {{Lebensmittelchemie }},
number = {{5}},
pages = {{S. 119}},
publisher = {{Wiley-VCH}},
title = {{{Polyphenolgehalte in alten und neuen Apfelsorten}}},
doi = {{https://doi.org/10.1002/lemi.201390053}},
volume = {{67}},
year = {{2013}},
}
@article{5385,
author = {{Weyland, Gerd and Stiebing, Achim}},
issn = {{0015-363x}},
journal = {{Fleischwirtschaft 93}},
number = {{10}},
pages = {{S. 81--83}},
title = {{{Was ist erlaubt, was verboten? - 9. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2013 - Teil 1 }}},
volume = {{93}},
year = {{2013}},
}
@article{5386,
author = {{Weyland, Gerd and Stiebing, Achim}},
journal = {{Fleischwirtschaft 93}},
number = {{11}},
pages = {{S. 81--83}},
title = {{{Was ist erlaubt, was verboten? - 9. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2013 - Teil 2 }}},
volume = {{93}},
year = {{2013}},
}
@book{5387,
author = {{Schneider, Jan}},
publisher = {{Behrs-Verlag}},
title = {{{Biologische Stabilisierung durch Schutzgasanwendung in Packungen}}},
year = {{2013}},
}
@article{5494,
author = {{Schneider, Jan}},
journal = {{Getränkeherstellung }},
title = {{{Brennende Themen mit kühlem Kopf umsetzen}}},
year = {{2013}},
}
@book{5496,
author = {{Lange, H.}},
isbn = {{ 978-3-930037-96-4}},
publisher = {{Julius-Kühn-Institut}},
title = {{{Ingredients, Morphology and Color Changes of Herbal Drugs and Spices after Mechanical Saturated Steam Decontamination}}},
year = {{2013}},
}
@article{5497,
author = {{Schwarzer, Knut and Dammann_, Anna and Lange, H. and Krüger, H. and Müller, Ulrich}},
journal = {{Z. Arznei- und Gewürzpflanzen }},
number = {{3}},
pages = {{S. 111--118}},
title = {{{Mechanische Sattdampfentkeimung von Medizinaldrogen mit unterschiedlichen Oberflächeneigenschaften}}},
volume = {{18}},
year = {{2013}},
}
@inproceedings{5498,
author = {{Stiebing, Achim}},
keywords = {{Vorträge und Präsentationen}},
title = {{{Kochsalz-Reduktion bei Rohwürsten – Grenzen und Möglichkeiten}}},
year = {{2013}},
}
@inproceedings{5499,
author = {{Müller, Ulrich}},
title = {{{Mikrobiologie-Datenbank Lemgo – D- und z-Werte Lebensmittel-relevanter Mikroorganismen oder ‚Die Lemgo D- and z-value Database for Food‘ (LDzBase)“}}},
year = {{2013}},
}
@inproceedings{5500,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann_, Anna and Müller, Ulrich}},
location = {{München}},
title = {{{Gentle Beverage Pasteurisation}}},
year = {{2013}},
}
@inproceedings{5501,
author = {{Stiebing, Achim}},
location = {{Lemgo}},
title = {{{ Nährwertveränderte Brühwürste - Einfluss von Zutaten und Zusatzstoffen auf die funktionellen Eigenschaften}}},
year = {{2013}},
}
@misc{12041,
author = {{Kamke, Dominic and Bennyassine, A. and Kutz, Gerd and Meier, S.}},
location = {{Istanbul (Türkei)}},
title = {{{Investigation of Film Coating Processes in an Innojet Air Coater (IAC 025) using two Coating Formulations}}},
year = {{2012}},
}
@misc{12044,
author = {{Kellner, Theresa and Kamke, Dominic and Kutz, Gerd and Dietrich , S.}},
location = {{Istanbul (Türkei)}},
title = {{{Continuous In-Line Particle Sizing during High-Shear Granulation for Process Control}}},
year = {{2012}},
}
@misc{12045,
author = {{Kutz, Gerd}},
location = {{München}},
title = {{{Cosmetic formulations workshop}}},
year = {{2012}},
}
@article{2538,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{67 -- 68}},
title = {{{Was ist erlaubt, was verboten? : 7 Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2011 - Teil 1}}},
volume = {{91}},
year = {{2012}},
}
@article{2540,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{72 -- 77}},
title = {{{Was ist erlaubt, was verboten? : 7 Lemgoer Lebensminelrechtstagung Fleisch + Feinkost 2011 - Teil 2}}},
volume = {{91}},
year = {{2012}},
}
@article{2542,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{10}},
pages = {{56 -- 62}},
title = {{{Was ist erlaubt, was verboten? : 7. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2011 - Teil 3}}},
volume = {{91}},
year = {{2012}},
}
@inproceedings{2575,
author = {{Upmann, Matthias}},
location = {{Berlin}},
title = {{{Histologische Bewertung von Muskelstrukturveränderungen bei Kochpökelwaren. Kriterienkatalog und Laborvergleichsuntersuchungen}}},
year = {{2012}},
}
@inproceedings{2576,
author = {{Upmann, Matthias}},
location = {{Berlin}},
title = {{{Qualitätsaspekte von dekontaminiertem Fleisch}}},
year = {{2012}},
}
@inproceedings{2577,
author = {{Upmann, Matthias and Beneke, B. and Grünewald, T. and Hildebrandt, G.}},
location = {{Garmisch-Partenkirchen}},
title = {{{Histologische Struktur von Köchpökelwaren – Bewertungskriterien für Strukturveränderungen}}},
year = {{2012}},
}
@inproceedings{2578,
author = {{Upmann, Matthias and Röser, Anja and Spitzer, D.}},
location = {{Garmisch-Partenkirchen}},
title = {{{Histologische Fettgehaltsbestimmung von Brühwurst – eine Alternative zur chemischen Analytik?}}},
year = {{2012}},
}
@inproceedings{2579,
author = {{Upmann, Matthias and Hölscher, M. and Kelliger, H. and Müller, T. and Stiebing, Achim}},
location = {{Lemgo}},
title = {{{Nachhaltigskeitsstandards für die Schweineschlachtung, Zerlegung und Verarbeitung von Schweinefleisch}}},
year = {{2012}},
}
@article{2665,
author = {{Kutz, Gerd and Anna Skala, Monika and Feldbusch, Natalja and Perlich, Dennis}},
issn = {{1616-7074}},
journal = {{Die pharmazeutische Industrie : pharmind ; europharm}},
number = {{4}},
pages = {{630 -- 636}},
publisher = {{Editio-Cantor-Verl. für Medizin und Naturwiss.}},
title = {{{Systematische Untersuchung zur Prozessvalidierung ethoxylathaltiger Emulsionssysteme}}},
volume = {{74}},
year = {{2012}},
}
@inproceedings{4468,
author = {{Kutz, Gerd and Schubert, O. E.}},
location = {{Detmold}},
title = {{{APV basics}}},
year = {{2012}},
}
@inproceedings{4469,
author = {{Kutz, Gerd}},
booktitle = {{Praktikum: Emulsionen – Weiterbildung an der Hochschule Ostwestfalen-Lippe}},
location = {{Detmold}},
title = {{{APV basics}}},
year = {{2012}},
}
@article{2750,
author = {{Dammann, Anna and Schwarzer, Knut and Vullriede, T. and Müller, Ulrich and Schneider, Jan}},
issn = {{1613-2041}},
journal = {{Brewing science}},
number = {{9/10}},
pages = {{134 -- 139}},
publisher = {{Carl}},
title = {{{Determination of the Kinetic Parameters of a Time-Temperature Integrator for the Flash Pasteurization}}},
volume = {{65}},
year = {{2012}},
}
@misc{2816,
author = {{Frahm, Björn and Brod, H.}},
booktitle = {{Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009}},
isbn = {{978-94-007-0883-9}},
issn = {{978-94-007-0884-6}},
location = {{ Dublin, Ireland}},
pages = {{355--359}},
publisher = {{Springer}},
title = {{{Improving Cell Culture Bioreactor Performance for Sensitive Cell Lines by Dynamic Membrane Aeration (DMA)}}},
doi = {{10.1007/978-94-007-0884-6_56}},
volume = {{vol. 5}},
year = {{2012}},
}
@misc{2877,
abstract = {{Die Erfindung betrifft einen Photobioreaktor mit Belichtung durch rotatorisch oszillierend bewegte Lichtquellen (Lichtleiter, LEDs) sowie optional kombiniert rotatorisch oszillierend bewegte Membranflächen zum Gastransport. Vorteile sind unter anderem ein im zeitlichen Mittel räumlich homogener Lichteintrag, welcher über Intensität und Oszillation an die Kultur und deren Dichte angepasst werden kann, sowie ein scherarmer Leistungseintrag und optional eine scherarme blasenfreie Be- und Entgasung. }},
author = {{Brod, Helmut and Frahm, Björn}},
pages = {{19}},
title = {{{Photobioreaktor mit rotatorisch oszillierenden Lichtquellen}}},
year = {{2012}},
}
@misc{2918,
author = {{Van Hecke, W. and Haltrich, D. and Frahm, Björn and Brod, H. and Ludwig, R.}},
booktitle = {{Achema 2012}},
location = {{Frankfurt am Main, Germany}},
publisher = {{Vogel Business Media}},
title = {{{Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor}}},
year = {{2012}},
}
@misc{2973,
author = {{Marzougui, R. and Pörtner, R. and Frahm, Björn}},
location = {{Freiburg, Germany}},
title = {{{Optimierung des Seed trains von Suspensions-Zellkulturen}}},
year = {{2012}},
}
@article{3402,
author = {{Schneider, Jan}},
issn = {{0936-4129}},
journal = {{Getränkeherstellung Deutschland}},
number = {{1}},
pages = {{6}},
publisher = {{Kuhn}},
title = {{{Was wäre wenn Beethovens Neunte erst jetzt komponiert wurde?}}},
year = {{2012}},
}
@article{3412,
author = {{Schneider, Jan}},
issn = {{0016-9323}},
journal = {{Gertränkeindustrie}},
number = {{2}},
pages = {{38--40}},
publisher = {{Sachon}},
title = {{{Freiheit für die Fachhochschulen : Die neue Rolle der FHs in einer sich wandelnden Hochschullandschaft}}},
volume = {{66}},
year = {{2012}},
}
@article{3539,
author = {{Schneider, Jan}},
issn = {{0016-9323}},
journal = {{Getränkeindustrie}},
number = {{1}},
pages = {{335}},
publisher = {{Sachon}},
title = {{{Zur Person : Prof. Dr.-Ing. Jan Schneider}}},
volume = {{66}},
year = {{2012}},
}
@inproceedings{3632,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Emulsionen im Spiegel von ICH- und PIC/S-Empfehlungen}}},
year = {{2012}},
}
@inproceedings{3633,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Rohstoffe und Formulierungsstrategien}}},
year = {{2012}},
}
@inproceedings{6172,
author = {{Schneider, Jan and Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich}},
location = {{Siegen}},
title = {{{The Way to gentle pasteurisation of beer and beverages}}},
year = {{2012}},
}
@inproceedings{6173,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
location = {{Stuttgart Hohenheim}},
title = {{{Untersuchungen zur Steigerung der Geschwindigkeit der Gefriertrocknung durch Bewegung des Trocknungsgutes}}},
year = {{2012}},
}
@inproceedings{6174,
author = {{Bilge, D. and Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich and Schneider, Jan and Woest, H.}},
location = {{Basilien}},
title = {{{Minimal Processing - a Way to a Gentle Pasteurization of Beer and Beverages}}},
year = {{2012}},
}
@inproceedings{6176,
author = {{Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich and Schneider, Jan}},
location = {{Dresden}},
title = {{{Bestimmung des Einflusses der Zeit- und Temperaturverteilung auf die Kurzzeiterhitzung von Getränken am Beispiel von Bier}}},
year = {{2012}},
}
@inproceedings{6177,
author = {{Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Homogenisier- und Emulgiertechnologie – ein kleiner Überblick}}},
year = {{2012}},
}
@inproceedings{6178,
author = {{Folz, R. and Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich and Woest, H. and Schneider, Jan}},
location = {{Russia}},
title = {{{Minimal Processing, a way to a gentle Pasteurization of Beer and Beverages}}},
year = {{2012}},
}
@inproceedings{5347,
author = {{Schwarzer, Knut and Schneider, Jan and Becker, Barbara and Müller, Ulrich and Dammann_, Anna}},
location = {{Stuttgart-Hohenheim}},
title = {{{Bestimmung des Einflusses der Zeit- und Temperaturverteilung auf die Kurzzeiterhitzung von Getränken am Beispiel von Bier}}},
year = {{2012}},
}
@inproceedings{5348,
author = {{Schwarzer, Knut and Schneider, Jan and Becker, Barbara and Müller, Ulrich}},
location = {{Stuttgart - Hohenheim}},
title = {{{Entkeimungsauslegung mit der "Lemgo D- and z-value Database for Food}}},
year = {{2012}},
}
@inproceedings{5349,
author = {{Müller, Ulrich and Werner, K.}},
location = {{Stuttgart-Hohenheim}},
title = {{{Visueller Nachweis mechanisch-trennender Verfahren zur Sporenreduktion}}},
year = {{2012}},
}
@inproceedings{5350,
author = {{Pfannebecker, Jens and Becker, Barbara}},
location = {{Warschau}},
title = {{{Comparison of a molecular detection system prototype with the DIN EN ISO-methods for the detection of Listeria monocytogenes and Salmonella enteritidis}}},
year = {{2012}},
}
@inproceedings{5351,
author = {{Müller, Ulrich}},
location = {{Köln}},
title = {{{Stable Emulsions by Direct Homogenization}}},
year = {{2012}},
}
@article{5352,
author = {{Lange, H. and Schwarzer, Knut and Dammann, Anna and Richert-Pöggeler, K.-R.}},
journal = {{Journal of Applied Botany and Food Quality 85}},
pages = {{S. 34--40}},
title = {{{Effects of steam and vacuum administration during decontamination on essential oil content in herbal medicines}}},
year = {{2012}},
}
@article{5353,
author = {{Müller, T. and Stiebing, Achim and Dederer, I.}},
journal = {{Fleischwirtschaft 92 }},
number = {{1}},
pages = {{S. 93--98}},
title = {{{Rohschinken und Rohwürste aus Eberfleisch}}},
volume = {{92}},
year = {{2012}},
}
@article{5354,
author = {{Lange, H. and Dammann, Anna and Schwarzer, Knut and Müller, Ulrich and Krüger, H.}},
journal = {{Z. Arznei- und Gewürzpflanzen 17 }},
number = {{4}},
pages = {{S. 174--181}},
title = {{{Chemical, physical and sensory changes of herbal drugs after saturated steam decontamination}}},
volume = {{17}},
year = {{2012}},
}
@inproceedings{5355,
author = {{Bilge, B. and Dammann, Anna and Schwarzer, Knut and Müller, Ulrich and Schneider, Jan and Woest, H.}},
title = {{{Minimal Processing - A Way to a Gentle Pasteurization of Beer and Beverages}}},
year = {{2012}},
}
@inproceedings{5356,
author = {{Behler, M. and Queisser, K. and Oppermann, L. and Jacoby, E. and Lier, J. and Broeker, Timo and Schneider, Jan}},
location = {{Hamburg}},
title = {{{Entwicklung und Herstellung des fermentierten alkoholischen Getränks ALEicious}}},
year = {{2012}},
}
@inproceedings{5357,
author = {{Steffens, M. and Schneider, Jan}},
location = {{Dresden}},
title = {{{Entschlüsselung der traditionellen Wasserkefirrezeptur zum Scale-Up}}},
year = {{2012}},
}
@inproceedings{5374,
author = {{Schwarzer, Knut and Dammann_, Anna and Krüger, H. and Lange, H. and Müller, Ulrich}},
location = {{Dresden}},
title = {{{Mechanische Sattdampfentkeimung von Drogen}}},
year = {{2012}},
}
@inproceedings{5375,
author = {{Pliske, Roland and Müller, Ulrich and Kohlus, R.}},
location = {{Dresden}},
title = {{{Untersuchung zur Steigerung der Geschwindigkeit der Gefriertrocknung durch Bewegung des Trocknungsgutes}}},
year = {{2012}},
}
@inproceedings{5377,
author = {{Müller, Ulrich}},
location = {{Giessen}},
title = {{{Entkeimung pflanzlicher Rohstoffe für die Lebensmittelherstellung und pharmazeutische/r Produkte}}},
year = {{2012}},
}
@inproceedings{5378,
author = {{Müller, Ulrich}},
location = {{ Hochschule Ostwestfalen-Lippe, Lemgo}},
title = {{{Gegenstrominjektionstechnologie}}},
year = {{2012}},
}
@inproceedings{5379,
author = {{Müller, Ulrich}},
location = {{Hochschule Ostwestfalen-Lippe, Lemgo}},
title = {{{Homogenisier- und Emulgiertechnologie - ein kleiner Überblick}}},
year = {{2012}},
}
@misc{12983,
abstract = {{Background
A broad spectrum of pathogens is causative for respiratory tract infections, but symptoms are mostly similar. Therefore, the identification of the causative viruses and bacteria is only feasible using multiplex PCR or several monoplex PCR tests in parallel.
Methods
The analytical sensitivity of three multiplex PCR assays, RespiFinder-19, RespiFinder-SMART-22 and xTAG-Respiratory-Virus-Panel-Fast-Assay (RVP), were compared to monoplex real-time PCR with quantified standardized control material. All assays include the most common respiratory pathogens.
Results
To compare the analytical sensitivity of the multiplex assays, samples were inoculated with 13 different quantified viruses in the range of 101 to 105 copies/ml. Concordant results were received for rhinovirus, whereas the RVP detected influenzavirus, RSV and hMPV more frequently in low concentrations. The RespiFinder-19 and the RespiFinder-SMART-22 showed a higher analytical sensitivity for adenoviruses and coronaviruses, whereas the RVP was incapable to detect adenovirus and coronavirus in concentrations of 104 copies/ml. The RespiFinder-19 and RespiFinder-SMART-22A did not detect influenzaviruses (104 copies/ml) and RSV (103 copies/ml). The detection of all 13 viruses in one sample was only achieved using monoplex PCR. To analyze possible competitive amplification reactions between the different viruses, samples were further inoculated with only 4 different viruses in one sample. Compared to the detection of 13 viruses in parallel, only a few differences were found.
The incidence of respiratory viruses was compared in tracheal secretion (TS) samples (n = 100) of mechanically ventilated patients in winter (n = 50) and summer (n = 50). In winter, respiratory viruses were detected in 32 TS samples (64%) by RespiFinder-19, whereas the detection rate with RVP was only 22%. The most frequent viruses were adenovirus (32%) and PIV-2 (20%). Multiple infections were detected in 16 TS samples (32%) by RespiFinder-19. Fewer infections were found in summer (RespiFinder-19: 20%; RVP: 6%). All positive results were verified using monoplex PCR.
Conclusions
Multiplex PCR tests have a broad spectrum of pathogens to test at a time. Analysis of multiple inoculated samples revealed a different focus of the detected virus types by the three assays. Analysis of clinical samples showed a high concordance of detected viruses by the RespiFinder-19 compared to monoplex tests.}},
author = {{Dabisch-Ruthe, Mareike and Vollmer, Tanja and Adams, Ortwin and Knabbe, Cornelius and Dreier, Jens}},
booktitle = {{BMC Infectious Diseases}},
issn = {{1471-2334}},
keywords = {{Respiratory Virus, Elution Volume, Multiplex Assay, Multiple Infection, Bocavirus}},
number = {{1}},
publisher = {{Springer}},
title = {{{Comparison of three multiplex PCR assays for the detection of respiratory viral infections: evaluation of xTAG respiratory virus panel fast assay, RespiFinder 19 assay and RespiFinder SMART 22 assay}}},
doi = {{10.1186/1471-2334-12-163}},
volume = {{12}},
year = {{2012}},
}
@inproceedings{6455,
author = {{Müller, Ulrich and Wilkens, H.}},
location = {{Lemgo}},
title = {{{Tandem-Vortrag "Luftsterilfiltration“,„Grundlagen Luftfiltern“, „Die Qualität der Umgebungsluft nach der Filtration der Außenluft bis zum Einlass"}}},
year = {{2011}},
}
@misc{2350,
author = {{Van Hecke, Wouter and Haltrich, Dietmar and Frahm, Björn and Brod, Helmut and Dewulf, Jo and Van Langenhove, Herman and Ludwig, Roland}},
booktitle = {{Journal of Molecular Catalysis B: Enzymatic}},
issn = {{1381-1177}},
number = {{2}},
pages = {{154--161}},
publisher = {{Elsevier}},
title = {{{A biocatalytic cascade reaction sensitive to the gas–liquid interface: Modeling and upscaling in a dynamic membrane aeration reactor}}},
doi = {{10.1016/j.molcatb.2010.10.004}},
volume = {{68}},
year = {{2011}},
}
@article{2442,
author = {{Upmann, Matthias and Stiebing, Achim and Hölscher, Maike}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{12}},
pages = {{41--47}},
publisher = {{Dt. Fachverl.}},
title = {{{Rework mindert den Genusswert nicht : Sensorische Auswirkungen der Wiederverarbeitung von erhitztem Brühwurstbrät in Brühwürsten}}},
volume = {{91}},
year = {{2011}},
}
@article{2532,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{42 -- 47}},
title = {{{Was ist erlaubt, was verboten? : 6. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2010 - Teil 3}}},
volume = {{90}},
year = {{2011}},
}
@article{2536,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{72 -- 77}},
title = {{{Was ist erlaubt, was verboten? : 6. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2010 - Teil1}}},
volume = {{90}},
year = {{2011}},
}
@inproceedings{2570,
author = {{Upmann, Matthias}},
location = {{Lemgo}},
title = {{{Neue Technologien zur Herstellung von Kochschinken und Rohschinken, Möglichkeiten der analystischen Kontrolle}}},
year = {{2011}},
}
@inproceedings{2571,
author = {{Upmann, Matthias and Ewald, M. and Stiebing, Achim}},
location = {{Marienfeld}},
title = {{{Gegarte Geflügelbrusterzeugnisse - Einfluss der Herstellungstechnologie auf die Beschaffenheit}}},
year = {{2011}},
}
@inproceedings{2572,
author = {{Upmann, Matthias and Stiebing, Achim}},
booktitle = {{ALTS, 67. Arbeitstagung}},
location = {{Berlin}},
publisher = {{Springer }},
title = {{{Rework - Wiederverarbeitung von Brühwurst in Brühwurstspitzenqualitäten}}},
volume = {{67}},
year = {{2011}},
}
@article{2573,
author = {{Stiebing, Achim and Upmann, Matthias and Schmidt, B. and Thumel, Heinrich}},
journal = {{DLG-Expertenwissen Sensorik / DLG e.V., Ausschuss Sensorik}},
number = {{5}},
publisher = {{DLG, Ausschuss Sensorik}},
title = {{{Sensorische Analyse: Sensorik von Frischfleisch. Beeinflussende Faktoren und Analysenmethoden}}},
year = {{2011}},
}
@article{2695,
author = {{Stiebing, Achim and Upmann, Matthias and Hillgärtner, K.}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{86--91}},
title = {{{Anteil SB-verpackter Erzeugnisse dominiert - DLG-Qualitätsprüfungen 2014 - Rohwürste und Rohpökelwaren}}},
volume = {{91}},
year = {{2011}},
}
@article{2698,
author = {{Stiebing, Achim and Upmann, Matthias and Hillgärtner, K.}},
journal = {{Fleischwirtschaft}},
pages = {{86--91}},
title = {{{Anteil SB-verpackter Erzeugnisse gestiegen - DLG-Qualitätsprüfungen 2013 - Rohwürste und Rohpökelwaren}}},
volume = {{91}},
year = {{2011}},
}
@misc{9448,
author = {{Wilhelm, Patrick}},
booktitle = {{Lebensmitteltechnik}},
issn = {{0047-4290}},
number = {{11}},
pages = {{31}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Chemical Engineering + Applied Biotechnology. Erfolgreiche Kongresskombination in Berlin.}}},
year = {{2011}},
}
@inbook{2752,
author = {{Müller, Ulrich and Jordan, Volkmar}},
booktitle = {{Industrial scale natural products extraction}},
isbn = {{978-3-527-32504-7}},
pages = {{ 55--86}},
title = {{{Alternative Solvents in Plant Extraction}}},
year = {{2011}},
}
@article{2753,
author = {{Müller, Ulrich and Schneider, Peter and Bischoff, Friedrich and Bart, Hans-Jörg and Schlitter, Klaus and Jordan, Volkmar}},
issn = {{1521-4125}},
journal = {{Chemical engineering & technology}},
number = {{3}},
pages = {{452 -- 458}},
publisher = {{Wiley-VCH}},
title = {{{Plant Extraction with Aqueous Two-Phase Systems}}},
volume = {{34}},
year = {{2011}},
}
@misc{2876,
abstract = {{Die Erfindung betrifft einen Begaser zum Eintrag eines Gases oder Gasgemisches in eine Flüssigkeit sowie ein Verfahren zur Begasung von Flüssigkeiten. Der erf?ndungsgemäße Begaser umfasst einen Hohlraum, einen Gaseinlass zum Einleiten eines Gases in den Hohlraum und zwei oder mehr Flächen, die formschlüssig aufeinander gepresst sind oder gepresst werden können, so dass ein durch den Gaseinlass in den Hohlraum gedrücktes Gas durch die zwischen den zusammengepressten Flächen auftretenden Spalten entweicht. }},
author = {{Brod, Helmut and Frahm, Björn and Jenne, Marc and Kauling, Jörg and Schmitt, Franz and Seletzky, Juri}},
pages = {{32}},
title = {{{Flüssigkeitsbegaser}}},
year = {{2011}},
}
@misc{2972,
author = {{Van Hecke, W. and Haltrich, D. and Frahm, Björn and Brod, H. and Ludwig, R.}},
location = {{Berlin, Germany}},
title = {{{Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor}}},
year = {{2011}},
}
@article{3401,
author = {{Schneider, Jan}},
issn = {{0936-4129}},
journal = {{Getränkeherstellung Deutschland}},
number = {{11}},
pages = {{6}},
publisher = {{Kuhn}},
title = {{{Zukunft ist die Zeit danach : Verheißung oder Warnung?}}},
year = {{2011}},
}
@book{3517,
abstract = {{Das Werk vermittelt kompakt und praxisnah Grundlagenwissen. Behandelt werden die Themenbereiche Rohstoffe und Systematik, die unterschiedlichen Herstellprozesse sowie Prüfungen auf chemische, physikalische und mikrobiologische Stabilität.Es ist auch ein Kapitel zur biopharmazeutischen Charakterisierung enthalten.}},
author = {{Kutz, Gerd and Daniels, Rolf and Trommer, Hagen}},
isbn = {{978-3-87193-398-1}},
pages = {{208}},
publisher = {{ECV, Editio-Cantor-Verl. }},
title = {{{Emulsionen – Entwicklung, Herstellung, Prüfung}}},
volume = {{3}},
year = {{2011}},
}
@article{3518,
author = {{Kutz, Gerd and Hausschild, N. and Skala, M. A. }},
issn = {{2191-8341}},
journal = {{TechnoPharm : making science work}},
number = {{2}},
pages = {{136--143}},
publisher = {{ECV, Editio-Cantor-Verl.}},
title = {{{Statistische Versuchsplanung zur Festlegung von Prozessparametern bei Filmüberzugsverfahren im Vertical Centrifugel Coater 3-15}}},
volume = {{1}},
year = {{2011}},
}
@inproceedings{6168,
author = {{Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich and Krüger, H. and Langer, H.}},
location = {{Berlin;}},
title = {{{Schonende Entkeimung von Medizinaldrogen durch das Lemgoer Verfahren}}},
year = {{2011}},
}
@inproceedings{6170,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann_, Anna and Müller, Ulrich and Voetz, M.}},
location = {{Berlin}},
title = {{{Minimal Processing - Der Weg zur Produkt und Ressourcen schonenden Getränkepasteurisation}}},
year = {{2011}},
}
@article{6205,
author = {{Schneider, Pia and Bischoff, F. and Jordan, V. and Müller, Ulrich and Schlitter, K. and Bart, H.-J.}},
journal = {{Chem. Eng. Technol.}},
number = {{3}},
pages = {{452--458}},
title = {{{Plant extraction with Aquaeus Phase Systems}}},
volume = {{34}},
year = {{2011}},
}
@article{6206,
author = {{Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich and Schneider, Jan}},
issn = {{1866-5195 }},
journal = {{Brewing science : the scientific organ of the Weihenstephan Scientific Centre of the TU Munich, of Versuchs- and Lehranstalt für Brauerei in Berlin (VLB), of the Scientific Station for Breweries in Munich, of the Veritas laboratory in Zurich, of Doemens wba-Technikum Gmbh in Graefelfing/Munich = Monatsschrift für Brauwissenschaft }},
pages = {{32--40}},
publisher = {{Carl}},
title = {{{Flash Pasteurization of Beer - a Critical Review}}},
volume = {{64}},
year = {{2011}},
}
@inproceedings{5316,
author = {{Dammann, Anna and Schwarzer, Knut and Lange, H. and Krüger, H. and Müller, Ulrich}},
booktitle = {{21. Bernburger Winterseminar für Arznei- und Gewürzpflanzen Bernburg, 22./23.02.2011}},
location = {{Bernburg}},
title = {{{Schonende Entkeimung von Medizinaldrogen durch das Lemgoer Verfahren (Poster)}}},
year = {{2011}},
}
@inproceedings{5318,
author = {{Schneider, Pia and Müller, Ulrich and Bart, H.-J. and Schlitter, K. and Jordan, V.}},
booktitle = {{Jahrestreffen der ProcessNet-Fachausschüsse Extraktion, Fluidverfahrenstechnik, Mehrphasenströmung und Phytoextrakte – Produkte und Prozesse, Fulda, 03./04.03.2011}},
location = {{Fulda}},
title = {{{Tensid-Wasser-Systeme als innovative Technologie zur Extraktion von Phytostoffen am Beispiel der Modellpflanze Salvia tribola}}},
year = {{2011}},
}
@inproceedings{5319,
author = {{Pliske, Roland and Müller, Ulrich and Barnekow, Rainer}},
booktitle = {{ProcessNet-Fachausschussitzung Lebensmittelverfahrenstechnik, Vlaardingen/NL, 23./24.03.2011}},
location = {{Vlaardingen/NL}},
title = {{{Untersuchung zur Steigerung der Geschwindigkeit der Gefriertrocknung durch Bewegung des Trockengutes (Poster)}}},
year = {{2011}},
}
@inproceedings{5320,
author = {{Broeker, Timo and Steffens, M. and Schneider, Jan}},
booktitle = {{7th European Bioethanol Technology Meeting (Beitrag zum Konferenzband), Detmold, April 2011}},
location = {{Detmold}},
title = {{{Energetic conversion of residues from food processing with a focus on bioethanol}}},
year = {{2011}},
}
@misc{5321,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
title = {{{Trockengasspülung}}},
year = {{2011}},
}
@inproceedings{5322,
author = {{Mormann, S. and Becker, Barbara}},
booktitle = {{Fachsymposium Lebensmittelmikrobiologie, Damp, 04.-06.05.2011}},
location = {{Damp}},
title = {{{ Vergleich unterschiedlicher RNA-Extraktionskits und Primer-/Sondensysteme zum Nachweis von humanem Norovirus in Lebensmitteln mittels real-time RT-PCR}}},
year = {{2011}},
}
@inproceedings{5324,
author = {{Pfannebecker, Jens and Becker, Barbara}},
booktitle = {{ Fachsymposium Lebensmittelmikrobiologie, Damp (2011)}},
location = {{Damp}},
title = {{{Validierungsstudie eines kulturellen, mikrobiologischen Nachweissystems mit ausgewählten Rohstoffen (Poster)}}},
year = {{2011}},
}
@article{5325,
author = {{Schneider, Jan and Steffens, Marco and Berlenkamp, Uwe and Schlimme, Karin}},
issn = {{1435-358X }},
journal = {{Brewing and beverage industry. China }},
number = {{1}},
pages = {{31--37}},
publisher = {{Sachon}},
title = {{{Application of novel iron compounds in beverages }}},
year = {{2011}},
}
@article{5326,
author = {{Stiebing, Achim and Thumel, Heinrich}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{86--91}},
publisher = {{Dt. Fachverl. }},
title = {{{Prämierungen belegen hohes Niveau – DLG-Qualitätsprüfungen 2010 und 2011 – Rohwürste und Rohpökelwaren}}},
volume = {{91}},
year = {{2011}},
}
@article{5327,
author = {{Stiebing, Achim and Schmidt, Bastian}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{44--46}},
publisher = {{Dt. Fachverl.}},
title = {{{ Kennzeichnung nicht zwingend erforderlich – Einfluss von Transglutaminase auf den Zusammenhalt von Rohschinken mit unterschiedlichem Salzgehalt}}},
volume = {{91}},
year = {{2011}},
}
@article{5328,
author = {{Becker, Barbara}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{1}},
pages = {{41--43}},
publisher = {{Dt. Fachverl.}},
title = {{{Mikrobiologische Richt- und Warnwerte : Über die Arbeit der Fachgruppe Lebensmittelmikrobiologie und -hygiene der DGHM und die Ermittlung von Richt- und Warnwerten}}},
volume = {{91}},
year = {{2011}},
}
@article{5329,
author = {{Becker, Barbara}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{69--70}},
publisher = {{Dt. Fachverl.}},
title = {{{Erstmals Essig in der Prüfung}}},
volume = {{91}},
year = {{2011}},
}
@article{5331,
author = {{Zapp, Jürgen}},
issn = {{1521-3811}},
journal = {{Lebensmittelchemie : Zeitschrift d. Lebensmittelchemischen Gesellschaft, Fachgruppe in der Gesellschaft Deutscher Chemiker }},
number = {{2}},
pages = {{33--34}},
publisher = {{Wiley-VCH }},
title = {{{Wiederholbarkeit der Mehrdimensionalen Chromatographie bei der Bestimmung von Kaffee-Aroma}}},
doi = {{https://doi.org/10.1002/lemi.201290041}},
volume = {{65}},
year = {{2011}},
}
@inproceedings{5334,
author = {{Pliske, Roland and Müller, Ulrich and Barnekow, Rainer}},
location = {{Vlaardingen / NL}},
title = {{{Untersuchung zur Steigerung der Geschwindigkeit der Gefriertrocknung durch Bewegung des Trockengutes}}},
year = {{2011}},
}
@inproceedings{5335,
author = {{Broeker, Timo and Steffens, M. and Schneider, Jan}},
location = {{Detmold}},
title = {{{Energetic conversion of residues from food processing with a focus on bioethanol}}},
year = {{2011}},
}
@misc{5337,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
title = {{{Trockengasspülung}}},
year = {{2011}},
}
@inproceedings{5338,
author = {{Mormann, S. and Becker, Barbara}},
location = {{Damp }},
title = {{{Vergleich unterschiedlicher RNA-Extraktionskits und Primer-/Sondensysteme zum Nachweis von humanem Norovirus in Lebensmitteln mittels real-time RT-PCR}}},
year = {{2011}},
}
@inproceedings{5340,
author = {{Pfannebecker, Jens and Becker, Barbara}},
location = {{Damp}},
title = {{{Validierungsstudie eines kulturellen, mikrobiologischen Nachweissystems mit ausgewählten Rohstoffen}}},
year = {{2011}},
}
@article{5341,
author = {{Stiebing, Achim and Thumel, H.}},
journal = {{Fleischwirtschaft }},
number = {{9}},
pages = {{86--91}},
title = {{{Prämierungen belegen hohes Niveau – DLG-Qualitätsprüfungen 2010 und 2011 – Rohwürste und Rohpökelwaren}}},
volume = {{91}},
year = {{2011}},
}
@article{5342,
author = {{Stiebing, Achim and Schmidt, Bastian}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{S. 44--46}},
title = {{{Kennzeichnung nicht zwingend erforderlich – Einfluss von Transglutaminase auf den Zusammenhalt von Rohschinken mit unterschiedlichem Salzgehalt}}},
volume = {{91}},
year = {{2011}},
}
@article{5343,
author = {{Zapp, Jürgen and Torenz, R.}},
issn = {{1521-3811 }},
journal = {{ebensmittelchemie : Zeitschrift der Lebensmittelchemischen Gesellschaft, Fachgruppe in der Gesellschaft Deutscher Chemiker }},
number = {{2}},
pages = {{S. 33}},
publisher = {{Wiley-VCH}},
title = {{{Auswirkungen von Rohkaffeedämpfung und Röstung auf die Kaffeesäuren}}},
doi = {{ https://doi.org/10.1002/lemi.201290041}},
volume = {{65}},
year = {{2011}},
}
@article{5406,
abstract = {{
The pentacyclic triterpenes oleanolic acid (OA) and ursolic acid (UA) in Salvia triloba are attractive ingredients for cosmetic and pharmaceutical formulations. These triterpenoids are constitution isomers and differ only in the position of one methyl group in their chemical structures. Therefore it is difficult to achieve a baseline separation by standard RP-HPLC systems. Another challenge is that the complex plant contains a large variety of similar compounds. To achieve precise results for the target molecules, these compounds should be removed prior to analysis. Due to the large application of these two triterpenes, a fast quantification method is favored. If the triterpenes are extracted with aqueous two-phase systems, the target substances are enriched in a surfactant-rich phase. For this application, it is desirable to develop a method that is capable of quantifying both triterpenes directly by RP-HPLC without additional purification steps.
The optimal chromatographic conditions for pure substances as well as for crude surfactant-containing extracts were accomplished on a Nucleodur C18 ISIS column by isocratic elution with methanol/water/acetic acid/triethanolamine (90:10:0.04:0.02 v/v) as the mobile phase and a column temperature of 10°C. The flow rate was 0.6 mL/min, and the detection wavelength was 210 nm. With these parameters, a baseline separation was achieved and the calibration curve showed a very good linearity (R2 > 0.999 for OA and UA) within the test range. The method is simple, rapid, and reliable for the quantification of crude extracts from plant material.
}},
author = {{Schneider, Pia and Hosseiny, S. S. and Bischoff, F. and Müller, Ulrich and Bart, H. J. and Schlitter, K. and Jordan, V.}},
issn = {{1525-6030}},
journal = {{Instrumentation Science & Technology}},
keywords = {{oleanolic acid, Salvia triloba, surfactants, triterpenes, ursolic acid}},
pages = {{407--418}},
title = {{{SURFACTANT MEDIATED EXTRACTION OF TRITERPENES AND THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM}}},
doi = {{10.1080/10739149.2011.602167}},
year = {{2011}},
}
@inproceedings{5409,
author = {{Pliske, Roland and Müller, Ulrich}},
location = {{Berlin}},
title = {{{Investigation on increasing the velocity of the freeze drying by friction effects}}},
year = {{2011}},
}
@inproceedings{5410,
author = {{Zapp, Jürgen and Wagner, A.}},
booktitle = {{Fachtagung Numerische Strömungssimulation}},
location = {{Lemgo}},
title = {{{Numerische Strömungssimulation in der Verfahrenstechnik}}},
year = {{2011}},
}
@inproceedings{5411,
author = {{Becker, Barbara}},
booktitle = {{Fresenius Tagung "Analytik und QS", Mainz, 13./14.10.2011}},
location = {{Mainz}},
title = {{{Mikrobiologische Richt- und Warnwerte aus der DGHM}}},
year = {{2011}},
}
@inproceedings{5412,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann, Anna and Müller, Ulrich and Voetz, M.}},
booktitle = {{Fresenius Fachtagung Abfüllung sensibler Getränke, Berlin, 29.-30.10.2011}},
location = {{Berlin}},
title = {{{Minimal Processing - Der Weg zur Produkt und Ressourcen schonenden Getränkepasteurisation}}},
year = {{2011}},
}
@inproceedings{5413,
author = {{Becker, Barbara}},
booktitle = {{GDL-Forum in Verbindung mit der EFFoST Annual Conference "Process-Structure-Functions-Relationships”, Berlin, 09.-11.11.2011}},
location = {{Berlin}},
title = {{{Bedeutung von Viren in der Lebensmittelproduktion}}},
year = {{2011}},
}
@inproceedings{5414,
author = {{Müller, Ulrich and Pliske, Roland}},
location = {{Paderborn}},
title = {{{Dynamische Gefriertrocknung in Feststoffmischern}}},
year = {{2011}},
}
@inproceedings{5415,
author = {{Schneider, Jan and Schwarzer, Knut and Dammann_, Anna and Müller, Ulrich and Voetz, M.}},
location = {{Berlin}},
title = {{{Ressourcen schonende Bierpasteurisation}}},
year = {{2011}},
}
@inproceedings{5416,
author = {{Becker, Barbara}},
booktitle = {{Rapid Microbiological Methods Conference, Berlin, 07./08.12.2011}},
location = {{Berlin}},
title = {{{Experience with Rapid Microbiological Methods in Food Testing}}},
year = {{2011}},
}
@inproceedings{5417,
author = {{Müller, Ulrich and Wilkens, H.}},
booktitle = {{8. Lemgoer Nachmittag zu Entkeimungsfragen, Hochschule Ostwestfalen-Lippe, Lemgo, 09.12.2011}},
location = {{Lemgo}},
title = {{{Tandem-Vortrag: "Luftsterilfiltration"("Grundlagen Luftfiltern", "Die Qualität der Umgebungsluft nach der Filtration der Außenluft bis zum Einlass")}}},
year = {{2011}},
}
@misc{12046,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Filterintegritätstestung}}},
year = {{2010}},
}
@misc{12050,
author = {{Hauschildt, N. and Skala, Monika Anna and Kutz, Gerd and Falck, H. }},
location = {{7th World Meeting on Pharmaceutics Biopharmaceutics and Pharmaceutical Technology}},
title = {{{Optimisation of film coating processes in a vertical centifugal coater by using design of experiments }}},
year = {{2010}},
}
@misc{12051,
author = {{Kutz, Gerd and Perlich, D.}},
location = {{Valletta (Malta)}},
title = {{{One Formulation - Two dosage forms: Processparameters determine the structure of emulsified systems}}},
year = {{2010}},
}
@misc{12052,
author = {{Feldbusch, Natalja and Kutz, Gerd}},
location = {{Valletta (Malta)}},
title = {{{Design of experiments as an effective tool to characterize relevant parameters during the production of disperes systems}}},
year = {{2010}},
}
@article{2522,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{57 -- 61}},
title = {{{Was ist erlaubt, was verboten? : 5. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 3}}},
volume = {{89}},
year = {{2010}},
}
@article{2528,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{57 -- 61}},
title = {{{Was ist erlaubt, was verboten? : 5. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 3}}},
volume = {{89}},
year = {{2010}},
}
@article{2530,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{46 -- 49}},
title = {{{Was ist erlaubt, was verboten? 5. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost - Teil 2}}},
volume = {{89}},
year = {{2010}},
}
@inproceedings{2568,
author = {{Gnegel, M. and Upmann, Matthias and Becker, Barbara and Seafkow, M.}},
title = {{{Einsatz des aquagroup Ifluenzverfahren (ai) in einre Messerdesinfektionsanlage zur Reinigung und Desinfektion von Schlachtmessern}}},
year = {{2010}},
}
@inproceedings{2569,
author = {{Upmann, Matthias}},
booktitle = {{Fortbildung Hygiene- und Qualitätsmanagement für Tierärzte}},
location = {{Hannover}},
title = {{{Lebensmittelhygiene: Fleisch}}},
year = {{2010}},
}
@article{2630,
abstract = {{The anaplerotic odd-medium-chain triglyceride triheptanoin is used in clinical trials for the chronic dietary treatment of patients with long-chain fatty acid oxidation disorders. We previously showed (Kinman RP, Kasumov T, Jobbins KA, Thomas KR, Adams JE, Brunengraber LN, Kutz G, Brewer WU, Roe CR, Brunengraber H. Am J Physiol Endocrinol Metab 291: E860–E866, 2006) that the intravenous infusion of triheptanoin increases lipolysis traced by the turnover of glycerol. In this study, we tested whether lipolysis induced by triheptanoin infusion is accompanied by the potentially harmful release of long-chain fatty acids. Rats were infused with heptanoate ± glycerol or triheptanoin. Intravenous infusion of triheptanoin at 40% of caloric requirement markedly increased glycerol endogenous Ra but not oleate endogenous Ra. Thus, the activation of lipolysis was balanced by fatty acid reesterification in the same cells. The liver acyl-CoA profile showed the accumulation of intermediates of heptanoate β-oxidation and C5-ketogenesis and a decrease in free CoA but no evidence of metabolic perturbation of liver metabolism such as propionyl overload. Our data suggest that triheptanoin, administered either intravenously or intraduodenally, could be used for intensive care and nutritional support of metabolically decompensated long-chain fatty acid oxidation disorders.}},
author = {{Gu, Lei and Zhang, Guo-Fang and Kombu, Rajan S. and Allen, Frederick and Kutz, Gerd and Brewer, Brewer and Roe, Charles R. and Brunengraber, Henri}},
issn = {{1522-1555}},
journal = {{American journal of physiology : Endocrinology and metabolism}},
number = {{2}},
pages = {{E362 -- E371}},
publisher = {{APS}},
title = {{{Parenteral and Enteral Metabolism of Anaplerotic Triheptanoin in Normal Rats. II. Effects on lipolysis, glucose production and liver acyl-CoA profile}}},
doi = {{https://doi.org/10.1152/ajpendo.00384.2009}},
volume = {{298}},
year = {{2010}},
}
@inproceedings{2711,
author = {{Kutz, Gerd}},
title = {{{Formulierungskonzepte für Emulsionen - ausgewählte Beispiele : Emulsionen -Formulierung Herstellung Charakterisierung}}},
year = {{2010}},
}
@article{4435,
author = {{Feldbusch, Natalja and Kutz, Gerd and Feiler, Stefanie and Solot, Philippe}},
issn = {{0009-2800 }},
journal = {{Chemie, Anlagen, Verfahren : CAV ; die Zeitschrift für Chemie- und Pharmatechnik }},
number = {{8}},
pages = {{54--55}},
publisher = {{Konradin-Verl. Kohlhammer }},
title = {{{Zwei auf einen Streich - Schnelle Identifikation wichtiger Parameter mittels Versuchsplanung}}},
volume = {{43}},
year = {{2010}},
}
@misc{4436,
author = {{Antonov, D. and Seyfarth, F. and Schliemann, S. and Terhaer, F. and Bock, M. and John, S. M. and Kleesz, P. and Pohlmann, D. and Kutz, Gerd and Elsner, P.}},
booktitle = {{Dermatologie in Beruf und Umwelt}},
issn = {{1616-7090}},
number = {{Nr. 2}},
pages = {{S. 90}},
publisher = {{Dustri-Verlag Dr. Karl Feistle GmbH}},
title = {{{Development of a test model for occupational hand-cleansers to quantify cleansing efficacy in relation to irritant otential}}},
volume = {{58}},
year = {{2010}},
}
@inproceedings{4472,
author = {{Kutz, Gerd}},
location = {{Hochschule-Ostwestfalen Detmold}},
title = {{{Emulsionen}}},
year = {{2010}},
}
@inproceedings{4473,
author = {{Kutz, Gerd}},
location = {{Hochschule Ostwestfalen-Lippe Detmold}},
title = {{{Praktikum: Aseptisches Arbeiten}}},
year = {{2010}},
}
@inproceedings{2729,
author = {{Kutz, Gerd and Walger, T.}},
location = {{Valletta (Malta)}},
title = {{{Optimisation of a Film Coating Process using Design of Experiments}}},
year = {{2010}},
}
@article{2748,
author = {{Schneider, Jan and Müller, Ulrich and Schwarzer, Knut and Becker, Barbara and Wilhelm, Patrick}},
issn = {{0934-9340}},
journal = {{Brauwelt International}},
number = {{5}},
pages = {{252 -- 256}},
publisher = {{Fachverlag Hans Carl GmbH}},
title = {{{Lemgo Database for D- and z-values: useful for beverage spoilage microorgansim}}},
year = {{2010}},
}
@article{2751,
author = {{Müller, Ulrich and Schwarzer, Knut and Dammann, Anna and Lange, Heinz and Krüger, Hans and David, Ricarda}},
journal = {{Zeitschrift für Arznei- und Gewürzpflanzen}},
number = {{2}},
pages = {{81 -- 85}},
publisher = {{Erling}},
title = {{{Entkeimung von Kapuzinerkresse (Tropaeolum majus L.) mittels »Mechanischer Sattdampfentkeimung«}}},
year = {{2010}},
}
@article{2754,
author = {{Müller, Ulrich and Schwarzer, Knut and Dammann, Anna and Lange, Heinz and Krüger, Hans}},
issn = {{1522-2640}},
journal = {{Chemie Ingenieur Technik}},
number = {{9}},
pages = {{1578 -- 1579}},
publisher = {{Wiley-VCH}},
title = {{{Wirkstoffgehalte von Medizinaldrogen nach mechanischen Sattdampfentkeimungen}}},
volume = {{82}},
year = {{2010}},
}
@article{2763,
author = {{Schwarzer, Knut and Schneider, Jan and Müller, Ulrich and Becker, Barbara and Wilhelm, Patrick}},
issn = {{ 0724-696X}},
journal = {{Brauwelt}},
number = {{18}},
pages = {{540 -- 544}},
publisher = {{Fachverlag Hans Carl GmbH}},
title = {{{Lemgoer Datenbank für D- und z-Werte: Anwendung für getränkeschädliche Mikroorganismen}}},
volume = {{150}},
year = {{2010}},
}
@misc{2815,
author = {{Dercks, B. and Frahm, Björn and Grünewald, M. and Kenig, E. and Lautenschleger, A. and Gorak, A. and Schmidt, P. and Sudhoff, D. and Ressler, S. and Zecirovic, R.}},
booktitle = {{Proceedings 19th International Congress of Chemical and Process Engineering}},
isbn = {{978-80-02-02250-3}},
location = {{Prague, CZ}},
publisher = {{Czech Society of Chemical Engineering}},
title = {{{Intensified absorption and distillation devices for modular chemical production processes}}},
year = {{2010}},
}
@misc{2873,
abstract = {{Die Erfindung betrifft ein Verfahren zur Reduzierung von Ablagerungen bei der Kultivierung von Organismen, insbesondere von Zellkulturen, welche zur Agglomeration bzw. Anhaftung an den Bioreaktor und seine Elemente neigen, oder bei denen Zelldebris oder Substanzen leicht agglomerieren bzw. anhaften.}},
author = {{Brod, Helmut and Frahm, Björn and Kauling, Jörg}},
pages = {{26}},
title = {{{Verfahren zur Reduzierung von Ablagerungen bei der Kultivierung von Organismen}}},
year = {{2010}},
}
@misc{2874,
abstract = {{Die Erfindung betrifft einen Bioreaktor, die Verwendung des Bioreaktors zur Kultivierung von Mikroorganismen oder Zellkulturen sowie ein Verfahren zur Kultivierung von Mikroorganismen oder Zellkulturen. }},
author = {{Brod, Helmut and Frahm, Björn and Jenne, Marc and Kauling, Jörg}},
pages = {{27}},
title = {{{Bioreaktor}}},
year = {{2010}},
}
@misc{2875,
abstract = {{Gegenstand der Erfindung ist ein neuartiges Begasungssystem, das insbesondere aber nicht ausschließlich in der Biotechnologie zur Versorgung von Zellen oder Mikroorganismen mit Sauerstoff einsetzbar ist. Das Begasungssystem umfasst eine Blasensäule und einen Verteiler. In dem Gefäß befindet sich ferner ein flüssiges Medium, das mit Gas versorgt werden soll. Es wird ein Vektor als Transportmittel für das Gas eingesetzt. Das Gas wird in die Blasensäule eingetragen und hier von dem Vektor aufgenommen. Der Vektor wird in Tropfenform über den Verteiler auf die Flüssigkeitsoberfläche aufgetragen, sinkt in dem Medium nach unten und gibt einen Teil des aufgenommenen Gases an das Medium ab. Am Boden des Gefäßes befindet sich eine Sammelvorrichtung, in der die Vektortropfen koaleszieren und wieder in die Blasensäule gelangen. Gegenstand der Erfindung ist weiterhin ein Bioreaktor umfassend das neuartige Begasungssystem. Gegenstand der Erfindung ist ferner ein Verfahren zur Begasung eines flüssigen Mediums, vorzugsweise einer Zellen oder Mikroorganismen enthaltenden wässrigen Suspension. }},
author = {{Frahm, Björn and Kauling, Jörg and Pütz, Andre and Schindler, Markus}},
pages = {{35}},
title = {{{Begasungssystem}}},
year = {{2010}},
}
@misc{2892,
author = {{Frahm, Björn and Brod, Helmut}},
location = {{Boston, USA}},
title = {{{Cultivation of sensitive cell lines - Improving bioreactor performance by Dynamic Membrane Aeration}}},
year = {{2010}},
}
@misc{2913,
author = {{Dercks, B. and Frahm, Björn and Grünewald, M. and Kenig, E. and Lautenschleger, A. and Gorak, A. and Schmidt, P. and Sudhoff, D. and Ressler, S. and Zecirovic, R.}},
location = {{Prague, Czech Republic}},
title = {{{Intensified absorption and distillation devices for modular chemical production processes}}},
year = {{2010}},
}
@article{3335,
author = {{Müller, Ulrich and Schulte, Helmut}},
issn = {{0047-4290 }},
journal = {{Lebensmitteltechnik}},
pages = {{30--31}},
publisher = {{LT Food-Medien-Verl.}},
title = {{{Flexibilität ist gefragt : Die industrielle Umsetzung des Sattdampfentkeimungsverfahrens}}},
year = {{2010}},
}
@article{3407,
author = {{Schneider, Jan and Steffens, Marco and Berlenkamp, Uwe and Schlimme, Karin}},
issn = {{0949-8877}},
journal = {{Brewing and Beverage Industry International}},
number = {{5}},
pages = {{84--89}},
publisher = {{Sachon}},
title = {{{Application of novel iron compounds in beverages }}},
year = {{2010}},
}
@article{3441,
author = {{Schneider, Jan and Steffens, Marco and Berlenkamp, Uwe and Schlimme, Karin}},
issn = {{0016-9323}},
journal = {{Gertränkeindustrie}},
number = {{7}},
pages = {{23--27}},
publisher = {{Sachon}},
title = {{{Innovative Eisenverbindungen Teil 2: Einflüsse auf Getränkeeigenschaften}}},
volume = {{64}},
year = {{2010}},
}
@article{3442,
author = {{Schneider, Jan and Steffens, Marco and Berlenkamp, Uwe and Schlimme, Karin}},
issn = {{0016-9323}},
journal = {{Gertränkeindustrie}},
number = {{6}},
pages = {{42--45}},
publisher = {{Sachon}},
title = {{{Innovative Eisenverbindungen Teil 1: Physiologische Aspekte und Stabilität in Getränken}}},
volume = {{64}},
year = {{2010}},
}
@inproceedings{3519,
abstract = {{Praktikum: Emulsionen}},
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Rohstoffe und Formulierungsstrategien}}},
year = {{2010}},
}
@inproceedings{3543,
author = {{Kutz, G}},
location = {{Detmold}},
title = {{{Sterilfiltration}}},
year = {{2010}},
}
@inproceedings{6143,
author = {{Schneider, P. and Bischoff, F. and Müller, Ulrich and Bart, H.-J. and Schlitter, K. and Jordan, V.}},
location = {{Karlsruhe}},
title = {{{Die Phytoextraktion mit Tensid-Wasser-Systemen am Beispiel der Triterpengewinnung aus Salbei}}},
year = {{2010}},
}
@inproceedings{6144,
author = {{Dammann_, Anna and Schwarzer, Knut and Lange, H. and Krüger, H. and Müller, Ulrich}},
location = {{Bonn}},
title = {{{Mechanische Sattdampfentkeimung – Alternative zu gängigen Entkeimungsverfahren}}},
year = {{2010}},
}
@inproceedings{6145,
author = {{Lange, H. and Dammann_, Anna and Schwarzer, Knut and Krüger, H. and Müller, Ulrich}},
location = {{Bonn}},
title = {{{Beeinflussung des Mikroorganismengehalts und der wertgebenden Inhaltsstoffe durch die Mechanische Sattdampfentkeimung}}},
year = {{2010}},
}
@inproceedings{6146,
author = {{Schwarzer, Knut and Lange, H. and Dammann_, Anna and Krüger, H. and Müller, Ulrich}},
location = {{Bonn}},
title = {{{Medizinaldrogen, Kräuter und mehr - Mögliche Einsatzgebiete der Mechanischen Sattdampfentkeimung}}},
year = {{2010}},
}
@inproceedings{6147,
author = {{Müller, Ulrich}},
location = {{Nuthetal}},
title = {{{Stand der Sattdampfentkeimung bei pflanzlichen Materialien}}},
year = {{2010}},
}
@inproceedings{6148,
author = {{Lange, H. and Schwarzer, Knut and Dammann_, Anna and H., Krüger and Müller, Ulrich}},
location = {{Stuttgart-Hohenheim}},
title = {{{Mechanische Sattdampfentkeimung von Arznei- und Gewürzpflanzen}}},
year = {{2010}},
}
@inproceedings{6149,
author = {{Lange, H. and Krüger, H. and Dammann_, Anna and Schwarzer, Knut and Müller, Ulrich}},
location = {{Aachen}},
title = {{{Wirkstoffgehalte von Medizinaldrogen nach mechanischen Sattdampfentkeimungen}}},
year = {{2010}},
}
@inproceedings{6150,
author = {{Müller, Ulrich}},
location = {{Fulda}},
title = {{{Emulsionsherstellung im industriellen Maßstab mittels Gegenstrominjektion}}},
year = {{2010}},
}
@inproceedings{6161,
author = {{Schwarzer, Knut and Wilhelm, Patrick and Krüger, H. and Lange, H. and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Die 'Lemgo D- and z-value Database for Food' (LDzBase) - ein Werkzeug zur genaueren Parametrierung von Entkeimungen in der Lebensmittelindustrie}}},
year = {{2010}},
}
@inproceedings{6166,
author = {{Dammann_, Anna and Schwarzer, Knut and Krüger, H. and Lange, H. and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Die mechanische Sattdampfentkeimung von Pflanzenmaterialien- und neuste Ergebnisse}}},
year = {{2010}},
}
@inproceedings{6167,
author = {{Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Entkeimung von festen pflanzlichen und flüssigen Substanzen – ein Überblick}}},
year = {{2010}},
}
@article{6231,
author = {{Müller, Ulrich and Schulte, H.}},
journal = {{Lebensmitteltechnik}},
number = {{1-2}},
pages = {{30--31}},
title = {{{Flexibilität ist gefragt – die industrielle Umsetzung des Sattdampfentkeimungsverfahrens}}},
year = {{2010}},
}
@article{6233,
author = {{Schwarzer, Knut and Schneider, J. and Müller, Ulrich and Becker, Barbara and Wilhelm, P.}},
journal = {{Brauwelt Internatinal V}},
pages = {{252--256}},
title = {{{Lemgo Database for D- and z-values: useful for beverage spoilage micro organism}}},
year = {{2010}},
}
@article{6234,
author = {{Müller, Ulrich and Schwarzer, Knut and Wilhelm, P. and Dammann_, Anna and Schneider, J.}},
journal = {{Lebensmitteltechnik}},
title = {{{Lemgoer Datenbank für D- und z-Werte}}},
volume = {{4}},
year = {{2010}},
}
@inbook{5339,
abstract = {{Viren verfügen über RNA oder DNA. Eine wirtsunabhängige Vermehrung ist somit nicht möglich. Zur Vermehrung benötigen Viren physiologisch intakte Wirtszellen, da sie im Rahmen ihrer Vermehrung auf deren Proteinsynthesemechanismen und die energieliefernden Stoffwechselprozesse zugreifen. Nach Infektion der Wirtszelle modifizieren sie die zellulären Prozesse in Hinblick auf einen optimalen Ablauf ihrer Replikation. Viren sind intrazelluläre Parasiten. Eine Virusvermehrung im Lebensmittel ist nicht möglich. Einige Viren können jedoch in Lebensmitteln überdauern und durch Lebensmittel übertragen werden. Zahlreiche Berichte belegen, dass viruskontaminierte Lebensmittel zu Krankheitsausbrüchen führten. Daraus ergeben sich Anforderungen an die Lebensmitteltechnologie, Lebensmittelhygiene und -untersuchung.}},
author = {{Becker, Barbara}},
booktitle = {{Molekularbiologische Methoden in der Lebensmittelanalytik}},
editor = {{Busch, Ulrich}},
isbn = {{978-3-642-10715-3}},
pages = {{107--120}},
publisher = {{Springer Verlag}},
title = {{{Molekularbiologische Methoden zum Nachweis lebensmittelübertragbarer Viren}}},
doi = {{10.1007/978-3-642-10716-0_8}},
year = {{2010}},
}
@misc{12255,
abstract = {{Vorgeschlagen wird eine Vorrichtung zum Testen von kosmetischen und pharmazeutischen Rohstoffen beinhaltend eine Membran, die über ein Behältnis gespannt wird, welches ein Hydrogel als tragenden Untergrund für die Membran enthält. }},
author = {{Bruns, Christiane and Kutz, Gerd and Prinz, Daniela}},
pages = {{1}},
title = {{{Hautmodell}}},
year = {{2009}},
}
@misc{2349,
author = {{Frahm, Björn and Brod, Helmut and Langer, Uwe}},
booktitle = {{Cytotechnology}},
issn = {{1573-0778}},
number = {{1}},
pages = {{17--30}},
publisher = {{Springer}},
title = {{{Improving bioreactor cultivation conditions for sensitive cell lines by dynamic membrane aeration}}},
doi = {{10.1007/s10616-009-9189-9}},
volume = {{59}},
year = {{2009}},
}
@misc{2361,
author = {{Becker, Barbara and Hildebrandt, Goetz and Erol, Irfan and Kleer, Josef and Manopas, Aranya Sira}},
booktitle = {{Fleischwirtschaft }},
number = {{7}},
pages = {{61--65}},
title = {{{Von der Döner - Prüfung zum Döner - Heariing}}},
year = {{2009}},
}
@article{2566,
author = {{Loncaric, D. and Paulsen, P. and Tichy, A. and Smulders, Frans J.M. and Upmann, Matthias}},
journal = {{Wiener Tierärztl. Monatsschr.}},
pages = {{135--144}},
title = {{{The microbiological effects of poor slaughter and processing hygiene in mutton production as determined by various marker organisms}}},
volume = {{96}},
year = {{2009}},
}
@inproceedings{2567,
author = {{Upmann, Matthias and Stucke, G. and Stiebing, A.}},
location = {{Lemgo}},
title = {{{Geflügelfleischverarbeitungsstandards und QUID - Werden Geflügelfleischerzeugnisse diskriminiert?}}},
year = {{2009}},
}
@article{2637,
abstract = {{Anaplerotic TH (glycerol triheptanoate) is used for the chronic oral treatment of long-chain fatty acid oxidation disorders (FOD). To test whether TH could also be used for the acute intravenous treatment of decompensated FOD patients, we investigated the metabolism and metabolic effects of triheptanoin emulsion administered parenterally or enterally. Rats were infused with TH emulsion (intravenously or intragastrically). Stable isotope tracers were infused intravenously to measure the rates of appearance (Ra) of plasma glucose, glycerol and fatty acids. Surprisingly, intravenous infusion of triheptanoin markedly increased glycerol Ra but not oleate Ra. This indicated that massive lipolysis induced by intravenous TH was not accompanied by the release of long-chain fatty acids from adipocytes. This probably results from the contribution of anaplerotic propionyl-CoA moiety of heptanoate to glyceroneogenesis in adipocytes, generating sufficient amounts of glycerol-3-phosphate to re-esterify the fatty acids derived from stimulated lipolysis. The intraduodenal infusion of TH did not induce lipolysis because TH was hydrolyzed in the gut. Our data support the use of intravenous TH emulsion for the acute treatment of FOD patients (for whom the release of fatty acids from adipocytes would be harmful). Supported by NIH.}},
author = {{Gu, Lei and Zhang, Guofang and S. Kombu, Rajan and Kutz, Gerd and Brewer, Wolf-Ulrich and Roe, Charles R. and Brunengraber, Henri}},
issn = {{1530-6860}},
journal = {{ The FASEB journal : the official journal of the Federation of American Societies for Experimental Biology}},
number = {{4}},
pages = {{506.3}},
publisher = {{Wiley}},
title = {{{Metabolism and metabolic effects of anaplerotic triheptanoin (TH) in normal rats}}},
doi = {{ https://doi.org/10.1096/fasebj.23.1_supplement.506.3}},
volume = {{23}},
year = {{2009}},
}
@inproceedings{3981,
author = {{Kutz, Gerd}},
location = {{Amman (Jordanien)}},
title = {{{Current Emulsification Techniques}}},
year = {{2009}},
}
@inbook{3985,
author = {{Kutz, Gerd}},
booktitle = {{Innovationen : Herausforderungen und Chancen}},
isbn = {{978-3-87846-271-2}},
publisher = {{Verlag für chemische Industrie}},
title = {{{Aktuelle Rohstoffe und Formulierungsstrategien}}},
volume = {{33}},
year = {{2009}},
}
@article{2823,
author = {{Müller, Ulrich and Triantafillaki, C. and Stegmann, I. and Wolf, A.}},
issn = {{0009-286X}},
journal = {{Chemie - Ingenieur - Technik : Verfahrenstechnik, technische Chemie, Apparatewesen, Biotechnologie}},
number = {{8}},
pages = {{1156 -- 1157}},
publisher = {{Wiley-VCH}},
title = {{{Gegenstrominjektionsverfahren zur Herstellung von Emulsionen}}},
volume = {{81}},
year = {{2009}},
}
@article{2824,
author = {{Müller, Ulrich and Lilie, Markus and Burgemeister, S. and Flaschel, E. and Friehs, K.}},
issn = {{0009-286X}},
journal = {{Chemie - Ingenieur - Technik : Verfahrenstechnik, technische Chemie, Apparatewesen, Biotechnologie}},
number = {{8}},
pages = {{1174}},
title = {{{Nachweis mechanischer Entkeimungseffekte bei der mtVDV-Entkeimung}}},
volume = {{81}},
year = {{2009}},
}
@article{2825,
author = {{Müller, Ulrich and Lilie, Markus and Zakowski, M. and Wilhelm, Patrick and Flaschel, E. and Friehs, K.}},
issn = {{0009-286X}},
journal = {{Chemie-Ingenieur-Technik}},
number = {{8}},
pages = {{1265}},
publisher = {{WILEY-VCH Verlag GmbH & Co. KGaA}},
title = {{{Nicht isotherme Modellierung der thermischen Inaktivierung in einem mtVDV-Prozess}}},
doi = {{10.1002/cite.200950333}},
volume = {{81}},
year = {{2009}},
}
@article{2826,
author = {{Müller, Ulrich and Gockel, S. and Ridder, M. and Wilhelm, Patrick}},
issn = {{0009-286X}},
journal = {{Chemie-Ingenieur-Technik}},
number = {{9}},
pages = {{1298 -- 1299}},
publisher = {{WILEY-VCH Verlag GmbH & Co. KGaA}},
title = {{{Dynamische Gefriertrocknung von Starterkulturen}}},
doi = {{10.1002/cite.200950313}},
volume = {{81}},
year = {{2009}},
}
@article{2835,
author = {{Müller, Ulrich}},
issn = {{0047-4290}},
journal = {{Lebensmitteltechnik : offizielles Organ der Gesellschaft Deutscher Lebensmitteltechnologen e.V. (GDL), des Vereins Österreichischer Lebensmittel- und Biotechnologen (VÖLB) sowie Partner im DLG-Netzwerk für Lebensmittelverarbeitung}},
number = {{12}},
pages = {{9 -- 10}},
publisher = {{LT Food-Medien-Verl.}},
title = {{{GDL-Kongress Lebensmitteltechnologie 2009 : Ein Branchen-Highlight im Lipperland}}},
year = {{2009}},
}
@article{2836,
author = {{Müller, Ulrich}},
issn = {{0047-4290 }},
journal = {{Lebensmitteltechnik : offizielles Organ der Gesellschaft Deutscher Lebensmitteltechnologen e.V. (GDL), des Vereins Österreichischer Lebensmittel- und Biotechnologen (VÖLB) sowie Partner im DLG-Netzwerk für Lebensmittelverarbeitung}},
number = {{10}},
pages = {{3}},
publisher = {{LT Food-Medien-Verl.}},
title = {{{GDL-Kongress 2009 : Lemgo bittet zum Wissenstransfer -und mehr}}},
year = {{2009}},
}
@misc{2872,
abstract = {{Die Erfindung betrifft eine Vorrichtung und ein Verfahren zur Rückhaltung und Rückführung von Zellen in einem kontinuierlich oder absatzweise durchströmten Gefäß. Ferner betrifft die Erfindung ein Verfahren zur Herstellung einer Vorrichtung, mit dem Zellen in einem kontinuierlich oder absatzweise durchströmten Gefäß zurückgehalten und zurückgeführt werden können. }},
author = {{Braun, Arndt and Brod, Helmut and Frahm, Björn and Jenne, Marc and Kauling, Jörg and Kirchner, Stephan}},
pages = {{35}},
title = {{{Verfahren und Vorrichtung zur Rückhaltung und Rückführung von Zellen}}},
year = {{2009}},
}
@misc{2912,
author = {{Frahm, Björn and Brod, H. and Langer, U.}},
location = {{Frankfurt am Main, Germany}},
title = {{{Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA)}}},
year = {{2009}},
}
@misc{2970,
author = {{Frahm, Björn and Brod, H. and Langer, U.}},
location = {{Dublin, Ireland}},
title = {{{Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA)}}},
year = {{2009}},
}
@misc{2971,
author = {{Van Hecke, W. and Van Langenhovve, H. and Frahm, Björn and Brod, H. and Dewulf, J. and Haltrich, D. and Ludwig, R.}},
location = {{Krakow, Poland}},
title = {{{Upscaling the biocatalytic conversion of lactose to lactobionic acid with the dynamic membrane aeration reactor}}},
year = {{2009}},
}
@article{3408,
author = {{Schneider, Jan}},
issn = {{0341-7115}},
journal = {{Brauindustrie }},
number = {{4}},
pages = {{14--18}},
publisher = {{Vereinigte Fachverl.}},
title = {{{Unterschiedliche Intentionen : Zur Bestimmung der Extraktausbeute im Sudhaus}}},
volume = {{94}},
year = {{2009}},
}
@article{3537,
author = {{Schneider, Jan and Cegelski, Margret and Radowski, Anette and Dörr, Tillmann}},
issn = {{0006-9329}},
journal = {{Brauwelt}},
number = {{6}},
pages = {{134--136}},
publisher = {{Carl}},
title = {{{Kohlenhydrate in Sportgetränken Teil 1: Untersuchungen im Markt befindlicher Sportgetränke}}},
year = {{2009}},
}
@article{3538,
author = {{Schneider, Jan and Cegelski, Margret and Radowski, Anette and Dörr, Tillmann}},
issn = {{0006-9329}},
journal = {{Brauwelt}},
number = {{7}},
pages = {{176--180}},
publisher = {{Carl}},
title = {{{Kohlenhydrate in Sportgetränken, Teil 2: Sensorische Eigenschaften und Osmolalitätsstabilität}}},
year = {{2009}},
}
@inproceedings{6122,
author = {{Müller, Ulrich and Triantafillaki, C. and Schneider, P. and Jordan, V.}},
location = {{Oberhausen}},
title = {{{Trennung komplexer Stoffgemische mit Mesophasensystemen}}},
year = {{2009}},
}
@inproceedings{6123,
author = {{Zakowski, M. and Schisnowski, D. and Bogdon, S. and Lilie, M. and Wilhelm, Patrick and Flaschel, E. and Friehs, K. and Müller, Ulrich}},
location = {{Lausanne}},
title = {{{Nicht-Isotherme Modellierung der thermischen Inaktivierung von Bacillus-Sporen}}},
year = {{2009}},
}
@inproceedings{6124,
author = {{Pilske, R. and Ukar, F. and Wang, J. and Triantafillaki, C. and Müller, Ulrich and Jordan, V.}},
location = {{Lausanne}},
title = {{{Bestimmung von Stoffübergangskoeffizienten bei der Phytostoffextraktion mittels Mesophasen}}},
year = {{2009}},
}
@inproceedings{6126,
author = {{Lilie, M. and Burgemeister, S. and Flaschel, E. and Friehs, K. and Müller, Ulrich}},
location = {{Lausanne}},
title = {{{Einsatz der Bildanalyse zum Nachweis mechanischer Entkeimungseffekte}}},
year = {{2009}},
}
@inproceedings{6127,
author = {{Triantafillaki, C. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Lausanne}},
title = {{{Gegenstrominjektionsverfahren zur Herstellung von Emulsionen}}},
year = {{2009}},
}
@inproceedings{6128,
author = {{Schwarzer, Knut and Becker, Barbara and Schneider, Jan and Müller, Ulrich}},
location = {{Lausanne}},
title = {{{Die Lemgo D- and z-value Datebase for Food (LDzBase): Ein Werkzeug zur Einführung von minimal processing in der Entkeimung}}},
year = {{2009}},
}
@inproceedings{6129,
author = {{Müller, Ulrich}},
location = {{Detmold}},
title = {{{Gewürze ohne Keime – Pro Inno am Beispiel eines Entkeimungsprojektes}}},
year = {{2009}},
}
@inproceedings{6130,
author = {{Krüger, H. and Lange, H. and Müller, Ulrich and Lilie, M.}},
location = {{Savigliano}},
title = {{{Changes in the composition of fennel and marjoram essential oils influenced by steam vacuum decontamination}}},
year = {{2009}},
}
@inproceedings{6131,
author = {{Müller, Ulrich}},
location = {{Bönen}},
title = {{{Mechanische Sattdampf-Entkeimung von pflanzlichen Materialien – ein Beispiel für die Kooperation von Mittelstand und Hochschule}}},
year = {{2009}},
}
@inproceedings{6132,
author = {{Müller, Ulrich and Triantafillaki, C. and Stegemann, I. and Wolf, A.}},
location = {{Mannheim}},
title = {{{Dynamische Gefriertrocknung von Starterkulturen}}},
year = {{2009}},
}
@inproceedings{6133,
author = {{Müller, Ulrich and Triantafillaki, C. and Stegemann, I. and Wolf, A.}},
location = {{Lemgo}},
title = {{{ProcessNet-Jahrestagung }}},
year = {{2009}},
}
@inproceedings{6135,
author = {{Müller, Ulrich and Triantafillaki, C. and Stegemann, I. and Wolf, A.}},
location = {{Lemgo}},
title = {{{Gegenstrominjektionsverfahren zur Herstellung von Emulsionen}}},
year = {{2009}},
}
@inproceedings{6136,
author = {{Lilie, M. and Burgemeister, S. and Flaschel, E. and Friehs, K. and Müller, Ulrich}},
location = {{Mannheim}},
title = {{{Nachweis mechanischer Entkeimungseffekte bei der mtVDV-Entkeimung}}},
year = {{2009}},
}
@inproceedings{6137,
author = {{Lilie, M. and Burgemeister, S. and Flaschel, E. and Friehs, K. and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{ProcessNet- Jahrestagung}}},
year = {{2009}},
}
@inproceedings{6139,
author = {{Lilie, M. and Zakowski, M. and Schisnowski, D. and Bogdon, S. and Flaschel, E. and Friehs, K. and Müller, Ulrich}},
location = {{Mannheim}},
title = {{{Nicht-Isotherme Modellierung der thermischen Inaktivierung in einem mtVDV-Prozess}}},
year = {{2009}},
}
@inproceedings{6140,
author = {{Lilie, M. and Zakowski, M. and Schisnowski, D. and Bogdon, S. and Flaschel, E. and Friehs, K. and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Nicht-Isotherme Modellierung der thermischen Inaktivierung in einem mtVDV-Prozess}}},
year = {{2009}},
}
@inproceedings{6141,
author = {{Schwarzer, Knut and Becker, Barbara and Schneider, Jan and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Die Lemgo D- and z-value Datebase for Food (LDzBase): Ein Werkzeug zur Einführung von minimal processing in der Entkeimung}}},
year = {{2009}},
}
@inproceedings{6142,
author = {{Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Mechano-thermische Entkeimungsverfahren von pflanzlichen Materialien}}},
year = {{2009}},
}
@misc{12982,
abstract = {{Contaminated food is a significant vehicle for human norovirus transmission. The present study determined the effect of physicochemical treatments on the tenacity of infective human norovirus genogroup II in selected foods. Artificially contaminated produce was subjected to a number of processes used by the food industry for preservation and by the consumer for storage and preparation. Virus recovery was carried out by using ultrafiltration and was monitored by using bacteriophage MS2 as an internal process control. Norovirus was quantified by using monoplex one-step TaqMan real-time reverse transcription (RT)-PCR and an external standard curve based on recombinant RNA standards. An RNase pretreatment step was used to avoid false-positive PCR results caused by accessible RNA, which allowed detection of intact virus particles. Significant reductions in titers were obtained with heat treatments usually applied by consumers for food preparation (baking, cooking, roasting). Generally, processes used for preservation and storage, such as cooling, freezing, acidification (≥pH 4.5), and moderate heat treatments (pasteurization), appear to be insufficient to inactivate norovirus within a food matrix or on the surface of food. Besides data for persistence in processed food, comparable data for individual matrix-specific protective effects, recovery rates, and inhibitory effects on the PCRs were obtained in this study. The established procedure might be used for other noncultivable enteric RNA viruses that are connected to food-borne diseases. The data obtained in this study may also help optimize the process for inactivation of norovirus in food by adjusting food processing technologies and may promote the development of risk assessment systems in order to improve consumer protection.}},
author = {{Mormann, Sascha and Dabisch-Ruthe, Mareike and Becker, Barbara}},
booktitle = {{ Applied and environmental microbiology / American Society for Microbiology}},
issn = {{1098-5336}},
number = {{2}},
pages = {{536--545}},
publisher = {{American Society for Microbiology}},
title = {{{Effects of Technological Processes on the Tenacity and Inactivation of Norovirus Genogroup II in Experimentally Contaminated Foods}}},
doi = {{10.1128/aem.01797-09}},
volume = {{76}},
year = {{2009}},
}
@misc{12056,
author = {{Kutz, Gerd and Liping, L. and Li, D.}},
location = {{Barcelona (Spanien)}},
title = {{{Process analysis of fluid bed granulation using risk assessment and design of experiments}}},
year = {{2008}},
}
@misc{12158,
author = {{Kutz, Gerd and Walger, T.}},
location = {{Barcelona (Spanien)}},
title = {{{Optimisation of a film Coating process using design of experiments}}},
year = {{2008}},
}
@article{2433,
author = {{Upmann, Matthias and Klein, Günter}},
journal = {{Rundschau für Fleischhygiene und Lebensmittelüberwachung }},
number = {{1}},
pages = {{14--15}},
title = {{{Visuelle Fleischuntersuchung bald auch bei Mastkälbern?}}},
volume = {{60}},
year = {{2008}},
}
@article{2463,
author = {{Upmann, Matthias and Langen, Marcus and Peters, Ulrike and Kein, Günter }},
journal = {{Rundschau für Fleischhygiene und Lebensmittelüberwachung }},
number = {{9}},
pages = {{354--355}},
title = {{{Genotypisierung von Campylobacter spp. in der Lebensmittelkette}}},
volume = {{58}},
year = {{2008}},
}
@article{2498,
author = {{Delcenserie, V. and Loncric, D. and Bonaparte, C. and Upmann, Matthias and China, B. and Daube, G. and Gavini, F.}},
journal = {{J. Appl. Microbiol.}},
pages = {{276--284}},
title = {{{Bifidobacteria as indicators of faecal contamination along a sheep meat production chain}}},
volume = {{104}},
year = {{2008}},
}
@inproceedings{2499,
author = {{Upmann, Matthias and Peters, U. and Langen, M. and Klein, G.}},
location = {{Garmisch-Partenkirchen}},
title = {{{Botulismus in einem Putenmastbetrieb - molekularbiologische Ermittlung einer potentielle Infektionsquelle}}},
year = {{2008}},
}
@article{2500,
author = {{Upmann, Matthias and Peters, U. and Langen, M. and Klein, G.}},
journal = {{Amtstierärztlicher Dienst und Lebensmittelkontrolle}},
title = {{{Botulismus in einem Putenmastbetrieb - molekularbiologische Ermittlung einer potentielle Infektionsquelle}}},
year = {{2008}},
}
@inproceedings{2501,
author = {{Upmann, Matthias and Peters, U. and Langen, M. and Beneke, B. and Klein, G.}},
location = {{Garmisch-Partenkirchen}},
title = {{{Diversität von Campyobacter-Isolaten aus biologischer und konventioneller Geflügelmast}}},
year = {{2008}},
}
@inproceedings{2502,
author = {{Upmann, Matthias and Peters, U. and Langen, M. and Beneke, B. and Klein, G.}},
booktitle = {{Amtstierärztlicher Dienst und Lebensmittelkontrolle}},
title = {{{Diversität von Campyobacter-Isolaten aus biologischer und konventioneller Geflügelmast}}},
year = {{2008}},
}
@inproceedings{3982,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Rohstoffe in Emulsionen}}},
year = {{2008}},
}
@article{3984,
author = {{Kutz, Gerd}},
issn = {{0942-7694}},
journal = {{SOFW-Journal : Home & personal care ingredients & formulations; Deutsche Ausgabe}},
number = {{9}},
pages = {{70--78}},
publisher = {{Verl. für Chemische Industrie, Ziolkowsky}},
title = {{{Aktuelle Rohstoffe und Formulierungsstrategien}}},
volume = {{134}},
year = {{2008}},
}
@inproceedings{3987,
author = {{Kutz, Gerd and Walger, T. and Feiler, S. and Solot, P.}},
location = {{Stoos (Schweiz)}},
title = {{{Optimisation of a film coating process using design of experiments}}},
year = {{2008}},
}
@inproceedings{3990,
author = {{Kutz, Gerd}},
location = {{Karlsruhe}},
title = {{{Pharmazeutische Emulsionen}}},
year = {{2008}},
}
@inproceedings{3991,
author = {{Kutz, Gerd}},
location = {{Tübingen}},
title = {{{Neue Rohstoffe und Formulierungsstrategien}}},
year = {{2008}},
}
@misc{9447,
author = {{Wilhelm, Patrick}},
booktitle = {{Lebensmitteltechnik}},
issn = {{0047-4290}},
number = {{11}},
pages = {{42 -- 43}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Mehr Nachhaltigkeit. ProcessNet behandelte energie- und rohstoffeffiziente Verfahren.}}},
year = {{2008}},
}
@techreport{2749,
author = {{Müller, Ulrich and Jordan, Volkmar and Triantafillaki, Christina and Schlitter, Klaus and Schneider, Peter}},
title = {{{Phytoextraktion mit wässrigen Zweiphasensystemen : wertvolle pflanzliche Inhaltsstoffe wie Oleanolsäure oder kosmetisch wirksame Substanzen sollen mit Hilfe von Mesophasen wässriger Tensidsysteme extrahiert werden ; ausführlicher Sachbericht zum Schlussbericht des FH3-Projekts ; Berichtszeitraum: 01.07.2006 - 31.12.2008}}},
year = {{2008}},
}
@article{2759,
author = {{Müller, Ulrich and Bart, Hans-Jürgen and Jordan, Volkmar and Schlitter, Klaus and Schneider, Pia}},
issn = {{1522-2640 }},
journal = {{Chemie-Ingenieur-Technik}},
number = {{9}},
pages = {{1292 -- 1293}},
publisher = {{Wiley-VCH}},
title = {{{Entwicklung eines Prozesses zur Phytoextraktion mit wässrigen Zweiphasensystemen}}},
doi = {{https://doi.org/10.1002/cite.200750575}},
volume = {{80}},
year = {{2008}},
}
@misc{2911,
author = {{Brod, H. and Kauling, J. and Frahm, Björn and Jenne, M. and Langer, U. and Bödeker, B.}},
location = {{Leverkusen, Germany}},
title = {{{Pushing the Limits in High-Density Mammalian Cell Fermentation}}},
year = {{2008}},
}
@misc{2968,
author = {{Frahm, Björn and Brod, H. and Burnett, M. and Langer, U. and Bödeker, B.}},
location = {{Palladium, Cologne, Germany}},
title = {{{High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA)}}},
year = {{2008}},
}
@misc{2969,
author = {{Frahm, Björn and Brod, Helmut}},
location = {{Leverkusen, Germany}},
title = {{{High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA)}}},
year = {{2008}},
}
@article{3530,
author = {{Schneider, Jan and Weber, I. and Pahl, R.}},
issn = {{0723-1520}},
journal = {{Brewing science}},
number = {{3}},
pages = {{105--112}},
publisher = {{Carl}},
title = {{{Measurement of Water Vapour Ingress in PET Bottles and Correlation with Oxygen and Carbon Dioxide Permeation}}},
volume = {{61}},
year = {{2008}},
}
@article{3531,
author = {{Schneider, Jan and Pahl, R. and Methner, F.-J. and Kowalczyk, J. and Hausmanns, S. and Radowski, A.}},
issn = {{0723-1520}},
journal = {{Brewing science}},
number = {{2}},
pages = {{49--55}},
publisher = {{Carl}},
title = {{{Study on the Applicability of Isomaltulose (Palatinose™ ) in Beer and Beer Specialties}}},
volume = {{61}},
year = {{2008}},
}
@inproceedings{6118,
author = {{Müller, Ulrich and Jordan, V. and Triantafillaki, C.}},
location = {{Bernburg/Saale}},
title = {{{Gewinnung von Wirkstoffen aus Arzneipflanzen mittels eines neuen Extraktionsverfahrens auf Basis von Mesophasen von Emulgatoren}}},
year = {{2008}},
}
@inproceedings{6119,
author = {{Müller, Ulrich}},
location = {{Paderborn}},
title = {{{Entkeimung von Naturstoffen in Feststoffmischern}}},
year = {{2008}},
}
@inproceedings{6120,
author = {{Schneider, P. and Jordan, V. and Schlitter, K. and Müller, Ulrich and Bart, H.-J. and Bischoff, F.}},
location = {{Clausthal-Zellerfeld}},
title = {{{Entwicklung eines Prozesses zur Phytoextraktion mit wässrigen Zweiphasensystemen}}},
year = {{2008}},
}
@inproceedings{6121,
author = {{Müller, Ulrich and Triantafillaki, C.}},
location = {{Gießen}},
title = {{{Phytoextraktion mit Mesophasen}}},
year = {{2008}},
}
@inproceedings{6446,
author = {{Lilie, M. and Wilhelm, Patrick and Müller, Ulrich and Walhorn, V. and Ros, R. and Anselmetti, D.}},
location = {{Zürich}},
title = {{{Haftkräfte vs. Ablösende Kräfte – Einsatz der Rasterkraftmikroskopie zur quantitativen Haftkraftmessung von Bacillus spp. Sporen}}},
year = {{2007}},
}
@inproceedings{6447,
author = {{Loskand, B. and Lilie, M. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Zürich}},
title = {{{Anlagenoptimierung bei der VDV-Entkeimung von pflanzlichen Materialien im bewegten Produktbett – Verbesserung der Produkteigenschaften und der Produktrückhaltung}}},
year = {{2007}},
}
@misc{12057,
author = {{Kutz, Gerd and Petrovic, S. and Walter, Marius}},
location = {{Nürnberg}},
title = {{{Re-Qualification of a fluid bed coater Type HCK 300TJ}}},
year = {{2007}},
}
@misc{12058,
author = {{Brauer, I. and Kutz, Gerd}},
location = {{Nürnberg}},
title = {{{Investigatioons regarding qualification and process validation of components of packaging lines}}},
year = {{2007}},
}
@misc{12070,
author = {{Kutz, Gerd and Salzmann, Volker and Weber, M.}},
location = {{Nürnberg}},
title = {{{Investigation regarding high shear homogenization as an alternative füor the production of submicron lipid particles}}},
year = {{2007}},
}
@misc{2348,
author = {{Frahm, Björn and Kirchner, S. and Kauling, J. and Brod, H. and Langer, U. and Bödeker, B.}},
booktitle = {{Chemie Ingenieur Technik}},
issn = {{0009-286X}},
number = {{7}},
pages = {{1052--1058}},
publisher = {{WILEY-VCH Verlag}},
title = {{{Dynamische Membranbegasung im Bioreaktor zur Intensivierung der Sauerstoffversorgung empfindlicher Zelllinien}}},
doi = {{10.1002/cite.200700070}},
volume = {{79}},
year = {{2007}},
}
@inbook{2423,
author = {{Upmann, Matthias and Nasser Al-Maasri, Abdul and Beckmann, Lutz and Atanassova, Viktoria and Reich, Felix and Klein, Günter}},
booktitle = {{Amtstierärztlicher Dienst und Lebensmittelkontrolle Sonderausgabe}},
location = {{Garmisch-Partenkirchen }},
pages = {{156}},
title = {{{Restriktionsenzymanalyse und geographische Verteilung von Campylobacter jejuni-lsolaten im Einzugsbereich eines Norddeutschen Geflügelschlachthofs}}},
year = {{2007}},
}
@inbook{2424,
author = {{Upmann, Matthias and Klein, Günter}},
booktitle = {{Amtstierärztlicher Dienst und Lebensmittelkontrolle Sonderausgabe}},
location = {{Garmisch-Partenkirchen }},
pages = {{141}},
title = {{{Nachweisgrenzen beim molekularbiologischen Allergennachweis (Senf, Sesam, Sellerie) mittels Real-time PCR}}},
volume = {{25}},
year = {{2007}},
}
@misc{2445,
author = {{Visscher, C. and Winter, Petra and Versphol, Jutta and Stratmann, Janin and Upmann, Matthias and Beyerbach, Martin and Kamphues, J.}},
booktitle = {{Proceedings of the Society of Nutrition Physiology = Berichte der Gesellschaft für Ernährungsphysiologie }},
isbn = {{9-3-7690-4100-2}},
location = {{Göttingen}},
pages = {{105}},
publisher = {{DLG-Verl.}},
title = {{{Field study on effects or feeding eoarsely ground diets (including organic acids) on the composition of caecum content (starch content/pH/vfa concentrations) and on salmonella prevalence of slaughtered pigs}}},
volume = {{16}},
year = {{2007}},
}
@article{2459,
author = {{Upmann, Matthias and Visscher, Christian and Winter, Petra and Versphol, Jutta and Stratmann-Selke, Janin and Beyerbach, Martin and Kamphues, Josef}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{7}},
pages = {{99--103}},
publisher = {{Dt. Fachverl.}},
title = {{{Effekte gröberen Futters und organischer Säuren auf die Salmonellenprävalenz bei Mastschweinen : Untersuchungen (Feldstudie) vor und nach der Schlachtung}}},
volume = {{87}},
year = {{2007}},
}
@inbook{2462,
author = {{Upmann, Matthias and Visscher, C. and Winter, Petra and Versphol, Jutta and Stratmann, Janin and Beyerbach, M. and Kamphues, J.}},
booktitle = {{Proceedings of the Society of Nutrition Physiology }},
pages = {{105}},
title = {{{Field study on effects of feeding coarsely ground diets (including organie acids) on the compositioo of eaecum content (starcb content/pHlvfa concentrations) aod 00 salmonella prevaleoce of slaugbtered pigs}}},
volume = {{16}},
year = {{2007}},
}
@article{2493,
author = {{Langen, M. and Peters, U. and Upmann, Matthias and Klein, G.}},
journal = {{Rundschau für Fleischhygiene und Lebensmittelüberwachung (RFL)}},
pages = {{354--355}},
title = {{{Genotypisierung von Campylobacter spp. In der Lebensmittelkette}}},
volume = {{58}},
year = {{2007}},
}
@inproceedings{2494,
author = {{Al-Masri, A.-N. and Reich, R. and Beckmann, L. and Atanassova, V. and Klein, G. and Upmann, Matthias}},
location = {{Garmisch-Partenkirchen }},
title = {{{Restriktionsenzymanalyse und geographische Verteilung von Campylobacter jejuni-Isolaten im Einzugsbereich eines norddeutschen Geflügelschlachthofs}}},
year = {{2007}},
}
@inproceedings{2495,
author = {{Upmann, Matthias and Klein, G.}},
location = {{Garmisch-Partenkirchen }},
title = {{{Nachweisgrenzen beim molekularbiologischen Allergennachweis (Senf, Sesam, Sellerie) mittels Real-time PCR}}},
year = {{2007}},
}
@inproceedings{2496,
author = {{Upmann, Matthias and Rüben, C. and Klein, G.}},
location = {{Halle (Westf.)}},
title = {{{Antimikrobielle Wirksamkeit von Inhaltsstoffen ätherischer Öle}}},
year = {{2007}},
}
@inbook{2497,
author = {{Upmann, Matthias and Rüben, C. and Klein, G.}},
booktitle = {{Proc. Gistazert-Tagung}},
location = {{ Halle (Westf.)}},
pages = {{56--60}},
title = {{{Antimikrobielle Wirksamkeit von Inhaltsstoffen ätherischer Öle}}},
year = {{2007}},
}
@article{2519,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{7}},
pages = {{21 -- 23}},
title = {{{Was ist erlaubt, was verboten? : 2. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2006 - Teil 1}}},
volume = {{86}},
year = {{2007}},
}
@article{2520,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{35 -- 40}},
title = {{{Was ist erlaubt, was verboten? : 2. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2006 - Teil 2}}},
volume = {{86}},
year = {{2007}},
}
@article{2521,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{83 -- 86}},
title = {{{Was ist erlaubt, was verboten? : 2. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2006 - letzter Teil}}},
volume = {{86}},
year = {{2007}},
}
@inproceedings{3992,
author = {{Kutz, Gerd}},
location = {{Moskau (Russland)}},
title = {{{Emulsification by rotor/stator- and rotor/systems}}},
year = {{2007}},
}
@inbook{3995,
author = {{Kutz, Gerd and Wolff, A.}},
booktitle = {{Pharmazeutische Produkte und Verfahren}},
editor = {{Kutz, Gerd and Wolff, Armin }},
isbn = {{978-3-527-31222-1}},
pages = {{1--4}},
publisher = {{WILEY-VCH}},
title = {{{Einführung}}},
doi = {{10.1002/9783527611133.ch1}},
year = {{2007}},
}
@inproceedings{4034,
author = {{Kutz, Gerd}},
location = {{Moskau ( Russland)}},
title = {{{Skin care formulations - from scratch to current applications}}},
year = {{2007}},
}
@inproceedings{4037,
author = {{Bödeker, A. and Bensmann, H. and Kutz, Gerd}},
location = {{Nürnberg}},
title = {{{Qualification of a packaging line for cylindrical containers and blister packs}}},
year = {{2007}},
}
@inproceedings{4038,
author = {{Kutz, Gerd}},
location = {{Basel (Schweiz)}},
title = {{{Formulierungskonzepte für Emulsionen - ausgewählte Beispiele}}},
year = {{2007}},
}
@misc{9446,
author = {{Wilhelm, Patrick}},
booktitle = {{Lebensmitteltechnik}},
issn = {{0047-4290}},
number = {{12}},
pages = {{30 -- 31}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Rund 1.200 Besucher. Ein Bericht von der ProcessNet-Jahrestagung 2007 in Aachen.}}},
year = {{2007}},
}
@book{2735,
abstract = {{Dieses Buch bietet einen umfassenden Überblick über die Anforderungen an pharmazeutische Produkte und Herstellungsverfahren. Es beschreibt detailliert die Prozesse, Produktionstechniken und -anlagen sowie die begleitenden Qualifizierungs- und Validierungsmaßnahmen.
}},
editor = {{Kutz, Gerd and Wolff, Armin}},
isbn = {{978-3-527-31222-1}},
pages = {{445}},
publisher = {{Wiley-VCH-Verl. }},
title = {{{Pharmazeutische Produkte und Verfahren}}},
doi = {{10.1002/9783527611133}},
year = {{2007}},
}
@misc{2814,
author = {{Pörtner, Ralf and Frahm, Björn and Lane, Paul and Munack, Axel and Kühn, Kathrin and Hass, Volker C.}},
booktitle = {{Cell Technology for Cell Products}},
isbn = {{978-1-402-05475-4}},
location = {{Harrogate, UK}},
pages = {{497--501}},
publisher = {{Springer}},
title = {{{Optimisation of Time-space-yield for Hybridoma fed-batch Cultures with an Adaptive Olfo-controller}}},
doi = {{10.1007/978-1-4020-5476-1_84}},
volume = {{vol. 3}},
year = {{2007}},
}
@article{2830,
author = {{Müller, Ulrich and Jordan, Volkmar and Triantafillaki, C.}},
journal = {{Chemie-Ingenieur-Technik}},
number = {{9}},
pages = {{1363}},
title = {{{Extraktion mit Mesophasen -Auswahl von geeigneten Emulgatoren zur Phytostoffgewinnung}}},
volume = {{79}},
year = {{2007}},
}
@article{2834,
author = {{Müller, Ulrich and Hein, Sven and Lilie, Markus and Wilhelm, Patrick}},
issn = {{1365-2621}},
journal = {{International Journal of Food Science and Technology}},
pages = {{190--193}},
publisher = {{WILEY-VCH Verlag GmbH & Co. KGaA}},
title = {{{Decontamination of spices by combining mechanical and thermal effects - an alternative approach for quality retention}}},
doi = {{10.1111/j.1365-2621.2006.01204.x}},
volume = {{42}},
year = {{2007}},
}
@misc{2870,
abstract = {{The procedure for gassing of liquid for cell cultures, comprises exchanging of gas over immersed membrane surfaces like hoses, cylinders or modules, and controlling the gassing rate change of the gas concentration and/or pressure of the gas or gas mixture or gas component flowing into/out of the area within the membrane surface. The membrane surface represents any rotatingly oscillating movement in the liquid. The gassing rate, transfer efficiency, mixing time and/or shear stress are controlled by change of the movement like amplitude and the equivalent number of revolutions. The procedure for gassing of liquid for cell cultures, comprises exchanging of gas over immersed membrane surfaces like hoses, cylinders or modules, and controlling the gassing rate change of the gas concentration and/or pressure of the gas or gas mixture or gas component flowing into/out of the area within the membrane surface. The membrane surface represents any rotatingly oscillating movement in the liquid. The gassing rate, transfer efficiency, mixing time and/or shear stress are controlled by change of the movement like amplitude, the equivalent number of revolutions, acceleration of the membrane surface, the delay of the membrane surface, the interruption of the movement or discontinuity. The course of motion is not restricted to recurring samples. The material transfer is increased by mounting of immovable current interfering elements. The disturb of the current forms by the rotatingly oscillating movement of the membrane surfaces. The supply of the membrane surface is undertaken with the help of flexible hoses or turning seals for the supply and discharge of gas. The membrane surface is used for the production of micro-bubbles or gas bubbles in the liquid. Rotor arms rotate in one of the rotation directions curved around the drive shaft. An independent claim is included for a device for gassing of liquid for cell cultures. }},
author = {{Brod, Helmut and Frahm, Björn and Kauling, Jörg and Rose, Reinhold}},
title = {{{Procedure for gassing of liquid for cell cultures, comprises exchanging of gas over immersed membrane surfaces and controlling the gassing rate change of the gas concentration and/or pressure of the gas or gas mixture or gas component}}},
year = {{2007}},
}
@misc{2871,
abstract = {{Gegenstand der Erfindung ist ein um seine ortsfeste, bevorzugt vertikale Achse oszillatorischrotierend angetriebener Reaktor für bevorzugt biotechnologische und pharmazeutische Anwendungen. Mit seinen prozessintensivierenden Eigenschaften für das Mischen, das Suspendieren, den Gasstofftransport, die Wärmeübertragung, die Bestrahlung und die Partikelrückhaltung wird die Anwendbarkeit im großtechnischen Maßstab gewährleistet. Der ohne Wellenabdichtung auskommende Reaktor erlaubt eine steriltechnisch besonders robuste Produktion unter Verzicht auf eine Reinigung und Reinigungsvalidierung erfordert, wenn der Reaktor als Einwegreaktor ausgeführt ist. }},
author = {{Brod, Helmut and Frahm, Björn and Kauling, Jörg and Poggel, Martin and Rose, Reinhold and Schmidt, Sebastian }},
pages = {{56}},
title = {{{Verfahren und Vorrichtung zur Be- und Entgasung von Flüssigkeiten, insbesondere in der Biotechnologie und speziell von Zellkulturen}}},
year = {{2007}},
}
@misc{2909,
author = {{Brod, Helmut and Frahm, Björn and Kauling, Jörg}},
location = {{Würzburg, Germany}},
title = {{{Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen}}},
year = {{2007}},
}
@misc{2910,
author = {{Brod, Helmut and Frahm, Björn and Kauling, Jörg}},
location = {{Osnabrück, Germany}},
title = {{{Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen}}},
year = {{2007}},
}
@misc{2967,
author = {{Frahm, Björn and Kirchner, S. and Rose, R. and Jenne, M. and Kauling, J. and Brod, H. and Jöris, K. and Wischniewski, M. and Langer, U. and Bödeker, B.}},
location = {{Leverkusen, Germany}},
title = {{{High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA)}}},
year = {{2007}},
}
@article{3529,
author = {{Schneider, Jan and Orzinski, M. and Hunger, W.}},
isbn = {{1866-5195}},
issn = {{0723-1520}},
journal = {{BrewingScience }},
number = {{3/4}},
pages = {{55--59}},
publisher = {{Carl}},
title = {{{Determination of oxygen ingress and carbon dioxide loss through plastic bottles using permeation simulation with hydrogen}}},
volume = {{60}},
year = {{2007}},
}
@inproceedings{6110,
author = {{Lilie, M. and Pfaff, R. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Zürich}},
title = {{{Haftkraftuntersuchungen an bakteriellen Sporen mittels eines Vakuum-Druck-Vakuum-Verfahrens am Beispiel von Bacillus spp.}}},
year = {{2007}},
}
@inproceedings{6111,
author = {{Müller, Ulrich and Lilie, M. and Wilhelm, Patrick}},
location = {{Bremerhaven}},
title = {{{Thermisch-letale Effekte und mechanische Ablösung bei der mechanischen Sattdampfentkeimung}}},
year = {{2007}},
}
@inproceedings{6112,
author = {{Triantafillaki, C. and Müller, Ulrich and Jordan, V.}},
location = {{Bremerhaven}},
title = {{{Extraktion mit Mesophasen – Das Potential von Emulgatoren zur Phytostoffgewinnung}}},
year = {{2007}},
}
@inproceedings{6113,
author = {{Triantafillaki, C. and Müller, Ulrich and Jordan, V.}},
location = {{Würzburg}},
title = {{{Extraktion von kosmetisch interessanten Wirkstoffen aus Pflanzen mittels Mesophasen}}},
year = {{2007}},
}
@inproceedings{6114,
author = {{Lilie, M. and Müller, Ulrich and Walhorn, V. and Ross, R. and Anselmetti, D. and Friehs, K. and Flaschel, E.}},
location = {{Hamburg}},
title = {{{Haftkraftuntersuchungen an bakteriellen.Sporen von Bacillus spp. in Luft und Wasser mittels Rasterkraftmikroskopie (AFM)}}},
year = {{2007}},
}
@inproceedings{6115,
author = {{Triantafillaki, C. and Müller, Ulrich and Jordan, V.}},
location = {{Hamburg}},
title = {{{Extraktion mit Mesophasen – Auswahl von geeigneten Emulgatoren zur Phytostoffgewinnung}}},
year = {{2007}},
}
@inproceedings{6116,
author = {{Müller, Ulrich and Triantafillaki, C. and Jordan, V.}},
location = {{Aachen}},
title = {{{Extraktion mit Mesophasen – Auswahl geeigneter Emulgatoren zur Phytostoffgewinnung}}},
year = {{2007}},
}
@inproceedings{6117,
author = {{Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Entkeimungsverfahren fester Substanzen – Eine kurze Übersicht}}},
year = {{2007}},
}
@article{6203,
author = {{Lilie, M. and Hein, S. and Wilhelm, P. and Müller, Ulrich}},
journal = {{International Journal of Food Science and Technology}},
pages = {{190--193}},
title = {{{Decontamination of Spices by Combining Mechanical and Thermal Effects – An Alternative Approach For Quality Retention}}},
volume = {{42}},
year = {{2007}},
}
@article{6204,
author = {{Müller, Ulrich and Triantafillaki, C. and Jordan, V.}},
journal = {{Chem.-Ing.-Tech.}},
number = {{9}},
pages = {{1363}},
title = {{{Extraktion mit Mesophasen – Auswahl geeigneter Emulgatoren zur Phytostoffgewinnung}}},
volume = {{79}},
year = {{2007}},
}
@inproceedings{6434,
author = {{Lilie, M. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Reinbek}},
title = {{{Energetische Betrachtungen zur Sattdampfentkeimung im fluidisierten Bett}}},
year = {{2006}},
}
@inproceedings{6435,
author = {{Rumke, T. and Wilhelm, Patrick and Müller, Ulrich and Lilie, M.}},
location = {{Reinbek}},
title = {{{Sattdampfentkeimung von Kamilleblüten unter Berücksichtigung qualitativer Aspekte}}},
year = {{2006}},
}
@inproceedings{6436,
author = {{Plassmeier, A. and Lilie, M. and Wilhelm, Patrick and Müller, Ulrich}},
keywords = {{Poster}},
location = {{Reinbek}},
title = {{{Das besondere Problem des ätherischen Öls bei der Sattdampfentkeimung von Majoran}}},
year = {{2006}},
}
@inproceedings{6437,
author = {{Müller, Ulrich}},
keywords = {{Dt. Sektion}},
location = {{Paderborn }},
title = {{{Integration von Trockenmischprozessen in eine Prozesskette}}},
year = {{2006}},
}
@inproceedings{6438,
author = {{Müller, Ulrich and Pahl, M.}},
keywords = {{Engl. Section}},
location = {{Paderborn}},
title = {{{Basic principles of dry blending}}},
year = {{2006}},
}
@inproceedings{6439,
author = {{Lilie, M. and Wilhelm, Patrick and Müller, Ulrich}},
keywords = {{Poster}},
location = {{Wiesbaden}},
title = {{{Anwendung der Flash-Verdampfung zur Entkeimung pflanzlicher Materialien}}},
year = {{2006}},
}
@inproceedings{6440,
author = {{Lilie, M. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Bernburg}},
title = {{{Anwendung der Flash-Verdampfung zur Entkeimung pflanzlicher Materialien}}},
year = {{2006}},
}
@inproceedings{6441,
author = {{Müller, Ulrich and Triantafillaki, C. and Jordan, V.}},
location = {{Berburg}},
title = {{{Gewinnung pflanzlicher Substanzen durch Mesophasen von Emulgatoren}}},
year = {{2006}},
}
@inproceedings{6442,
author = {{Müller, Ulrich}},
location = {{Lemgo}},
title = {{{VDI 4066 - Ziele einer neuen Richtlinie zur Abfüllung von flüssigen und pastösen Lebensmitteln – Grundlagen und Auslegungskriterien}}},
year = {{2006}},
}
@inproceedings{6443,
author = {{Lilie, M. and Loskand, B. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Anlagenoptimierung bei der Vakuum-Druck-Vakuum-Behandlung von pflanzlichen Materialien}}},
year = {{2006}},
}
@inproceedings{6444,
author = {{Wilhelm, Patrick and Althoff, T. and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Der erste Online D- und z-Wert Katalog - Hilfsmittel für Forschung und Praxis}}},
year = {{2006}},
}
@misc{12059,
author = {{Kutz, Gerd and Bruns, Christina and Salzmann, Volker}},
location = {{Lyon (Frankreich)}},
title = {{{Comparative studies on emulsion preparation using different processing facilities}}},
year = {{2006}},
}
@misc{12061,
author = {{Kutz, Gerd and Bruns, Christina and Enga, M. and Hening, S.}},
location = {{Lyon (Frankreich)}},
title = {{{Current food ingredients in cosmetic formulations and their effects on relevant skin parameters}}},
year = {{2006}},
}
@misc{12062,
author = {{Kutz, Gerd and Bruns, Christina and Hennigs, Sören and Enga, M.}},
location = {{Genf}},
title = {{{Current ingredients in semi-solid formulations and their effects on skin hydration, transepidermal water loss and water resistance}}},
year = {{2006}},
}
@misc{12063,
author = {{Kutz, Gerd}},
location = {{Nürnberg}},
title = {{{Galenical Characterisation of Skin Care Products}}},
year = {{2006}},
}
@misc{12065,
author = {{Kutz, Gerd and Salzmann, Volker and Bruns, Christina and Lewandrowski, A.}},
location = {{Genf}},
title = {{{Comparative studies on processing facilities with special regard to the new Co-Twister System }}},
year = {{2006}},
}
@misc{12067,
author = {{Bruns, Christina and Müller, R. H. and Prinz, D. and Kutz, Gerd}},
location = {{Genf}},
title = {{{Identification of topical excipients with high performance spreadabilit}}},
year = {{2006}},
}
@article{2425,
author = {{Upmann, Matthias and Klein, Günter and Reich, Felix and Peters, Ulrike and Nasser Al-Maasri, Abdul and Atanassova, Viktoria}},
journal = {{Forschung fürs Leben}},
pages = {{15--18}},
title = {{{Detektive im Schlachthof: Auf der Spur von Campylobacter}}},
year = {{2006}},
}
@article{2458,
author = {{Upmann, Matthias and Peters, Jan and Lienau, Jan-Alexander and Nähter, Gritt and Alter, Thomas}},
journal = {{Archiv für Lebensmittelhygiene}},
number = {{9/10}},
pages = {{136--140}},
title = {{{Resultate der ersten Phase des Nationalen Campylobacter-Masthähnchenmonitorings 2004-2005}}},
volume = {{57}},
year = {{2006}},
}
@article{2460,
author = {{Upmann, Matthias and Delcenserie, V. and Kopeinig, K. and Pollinger, S. and Beerens, H. and Gavani, F. and Bonaparte, C.}},
journal = {{Journal of Food Protection}},
number = {{4}},
pages = {{871--877}},
title = {{{Bifidobacterium Species Isolated from Animal Feces and from Beef and Pork Meat}}},
volume = {{69}},
year = {{2006}},
}
@inproceedings{2489,
author = {{Upmann, Matthias}},
location = {{Krefeld}},
title = {{{Einführung in die histologische Lebensmitteluntersuchung}}},
year = {{2006}},
}
@inproceedings{2490,
author = {{Upmann, Matthias}},
location = {{refeld}},
title = {{{Histologischer Nachweis von Verdickungsmitteln}}},
year = {{2006}},
}
@inproceedings{2491,
author = {{Upmann, Matthias and Gethmann, J. and Möller, M. and Schlieper, B. and Krapat, R.}},
location = {{Würzburg}},
title = {{{Reduzierung der Campylobacter-Belastung in der Lebensmittelkette}}},
year = {{2006}},
}
@inproceedings{2492,
author = {{Upmann, Matthias and Visscher, C. and Winter, P. and Stratmann, J. and Beyerbach, M. and Kamphues, J.}},
location = {{München}},
title = {{{Effekte bestimmter Fütterungsmaßnahmen in Schweinebeständen zur Reduktion der Salmonellenprävalenz – Ergebnisse einer Feldstudie. }}},
year = {{2006}},
}
@article{2518,
author = {{Stiebing, Achim and Weyland, Gerd}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{23 -- 26}},
title = {{{Was ist erlaubt, was verboten? : 1. Lemgoer Lebensmittelrechtstagung Fleisch + Feinkost 2005 - Teil 1}}},
volume = {{85}},
year = {{2006}},
}
@inproceedings{4134,
author = {{Kutz, Gerd}},
keywords = {{Scientific lecture}},
location = {{Zürich (Schweiz)}},
title = {{{Modern formulation concepts with actual raw materials}}},
year = {{2006}},
}
@misc{9445,
author = {{Wilhelm, Patrick}},
booktitle = {{Lebensmitteltechnik}},
issn = {{0047-4290}},
number = {{11}},
pages = {{44 -- 45}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Ressourcen im Blick. Ein Bericht von den GVC/Dechema Jahrestagungen 2006 in Wiesbaden.}}},
year = {{2006}},
}
@article{2734,
abstract = {{A new chronic treatment for inherited disorders of long-chain fatty acid oxidation involves administering up to one-third of dietary calories as triheptanoin, a medium-odd-chain triglyceride (Roe CR, Sweetman L, Roe DS, David F, and Brunengraber H. J Clin Invest 110: 259–269, 2002). Heptanoate and C5-ketone bodies derived from its partial oxidation in liver are precursors of anaplerotic propionyl-CoA in peripheral tissues. It was hypothesized that increasing anaplerosis in peripheral tissues would boost energy production. In the present study, we tested the potential of a triheptanoin emulsion as an intravenous nutrient. Normal rats were infused with triheptanoin intravenously or intraduodenally at up to 40% of caloric requirement. The blood concentration ratio (heptanoate/C5-ketone bodies) was high with intravenous and low with intraduodenal triheptanoin infusion. During intravenous infusion of triheptanoin, lipolysis was stimulated but appeared compensated by fatty acid reesterification. During intraduodenal infusion of triheptanoin, lipolysis was not stimulated. Our data support the hypothesis that intravenous triheptanoin could be used to treat decompensated patients with long-chain fatty acid oxidation disorders.}},
author = {{Kinman, Renèe P. and Kasumov, Takhar and Jobbins, Kathryn A. and Thomas, Katherine R. and Adams, Jillian E. and Brunengraber, Lisa N. and Kutz, Gerd and Brewer, Wolf-Ulrich and Roe, Charles R. and Brunengraber, Henri }},
journal = {{American journal of physiology, Endocrinology and metabolism}},
number = {{4}},
pages = {{E860 -- E868}},
publisher = {{APS}},
title = {{{Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats}}},
doi = {{https://doi.org/10.1152/ajpendo.00366.2005}},
volume = {{291}},
year = {{2006}},
}
@article{2832,
author = {{Müller, Ulrich and Lilie, Markus and Wilhelm, Patrick}},
issn = {{0009-286X}},
journal = {{Chemie-Ingenieur-Technik}},
number = {{9}},
pages = {{1243--1244}},
publisher = {{WILEY-VCH Verlag GmbH & Co. KGaA}},
title = {{{Anwendung der Flash-Verdampfung zur Entkeimung pflanzlicher Materialien}}},
doi = {{10.1002/cite.200650159}},
volume = {{78}},
year = {{2006}},
}
@article{2833,
author = {{Müller, Ulrich and Rumke, Tim and Wilhelm, Patrick and Lilie, Markus}},
issn = {{1431-9292}},
journal = {{Zeitschrift für Arznei- und Gewürzpflanzen}},
number = {{3}},
pages = {{142--144}},
publisher = {{ERLING Verlag GmbH & Co. KG}},
title = {{{Schonende Keimzahlreduktion bei Kamillenblüten (Chamomilla recutica (L.) Rauschert)}}},
volume = {{11}},
year = {{2006}},
}
@article{3409,
author = {{Schneider, Jan and Krottenthaler, Martin and Beck, Werner and Weisser, Horst}},
issn = {{0046-9750}},
journal = {{Journal of the Institute of Brewing}},
number = {{4}},
pages = {{380--387}},
publisher = {{Wiley & Sons Ltd.}},
title = {{{Study on the Membrane Filtration of Mash with Particular Respect to the Qualityof Wort and Beer}}},
volume = {{111}},
year = {{2006}},
}
@article{3410,
author = {{Schneider, Jan and Orzinski, Martin and Embs, Frank W. and Fritsch, Karsten and Weber, Ingrid}},
issn = {{0341-7115}},
journal = {{Brauindustrie}},
number = {{11}},
pages = {{50--57}},
title = {{{Monolayer-Barriere-Blend-PET-Flaschen : Untersuchung zur Eignung für die Bierabfüllung}}},
year = {{2006}},
}
@article{3445,
author = {{Schneider, Jan and Schröder, Gerhard and Kerwitz, Yvonne and Weber, Ingrid and Orzinski, Martin}},
journal = {{Brauwelt international}},
number = {{4}},
pages = {{218--222}},
title = {{{Effect of additives on chemical and tribological glass corrosion in washing of glass bottles}}},
year = {{2006}},
}
@misc{3520,
author = {{Schneider, Jan}},
booktitle = {{Lippische Landeszeitung}},
number = {{288}},
pages = {{17}},
title = {{{Bier aus einer Plastikflasche? : Das Interwiev mit Prof. Dr. Jan Schneider, Getränketechnologe an der Fachhochschule}}},
year = {{2006}},
}
@book{3534,
author = {{Schneider, Jan and Manger, Hans-J.}},
isbn = {{978-3-921690-55-0}},
pages = {{175}},
publisher = {{VLB}},
title = {{{Kälteanlagen in der Brau- und Malzindustrie}}},
year = {{2006}},
}
@article{3535,
author = {{Schneider, Jan and Kasprzyk, Andreas and Pahl, Roland and Orzinski, Martin}},
journal = {{Brauwelt}},
number = {{45}},
pages = {{1382--1388}},
title = {{{Pasteurisation kohlensäurehaltiger Erfrischungsgetränke in PET-Flaschen}}},
year = {{2006}},
}
@article{3536,
author = {{Schneider, Jan and Böttrich, A.-H. and Petreck, M. and Lange, T. and Wittmann, H.}},
journal = {{Brauwelt}},
number = {{48-49}},
pages = {{1499--1500}},
title = {{{Privatbrauerei Iserlohn - Neuverrohrung eines Gärkellers bei laufendem Betrieb : Gesteigerter Automatisierungsgrad}}},
volume = {{146}},
year = {{2006}},
}
@article{6202,
author = {{Rumke, T. and Lilie, M. and Wilhelm, P. and Müller, Ulrich}},
journal = {{Zeitschrift für Arznei- und Gewürzpflanzen}},
number = {{3}},
pages = {{142--144}},
title = {{{Schonende Keimzahlreduktion von Arznei- und Gewürzpflanzen am Beispiel von Matricariae flos}}},
volume = {{11}},
year = {{2006}},
}
@inproceedings{6421,
author = {{Lilie, M. and Wilhelm, Patrick and Hein, S. and Müller, Ulrich}},
location = {{Berlin}},
title = {{{Fortschritte bei der mechanischen Sattdampfentkeimung}}},
year = {{2005}},
}
@inproceedings{6422,
author = {{Giefers, C. and Müller, Ulrich and Brocklehurst, T.}},
location = {{Berlin}},
title = {{{Untersuchungen zur Anhaftung von Mikroorganismen auf Gemüseoberflächen}}},
year = {{2005}},
}
@inproceedings{6423,
author = {{Wilhelm, Patrick and Giefers, C. and Lilie, M. and Müller, Ulrich}},
location = {{Berlin}},
title = {{{Kalkulation thermischer Entkeimungseffekte beim Lemgoer Sattdampfentkeimungsverfahren auf Basis realer Temperaturverläufe}}},
year = {{2005}},
}
@inproceedings{6424,
author = {{Müller, Ulrich and Chchtian, S. and Jordan, V. and Schlitter, K.}},
keywords = {{Poster}},
location = {{Berlin}},
title = {{{Zur Entwicklung einer Phytostoff-Tensid-Extraktion}}},
year = {{2005}},
}
@inproceedings{6425,
author = {{Hein, S. and Lilie, M. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Berlin}},
title = {{{Produktschonende Entkeimung mit Sattdampf – Betrachtungen zur Veränderung des Gehaltes und der Zusammensatzung von ätherischen Ölen am Beispiel von schwarzem Pfeffer}}},
year = {{2005}},
}
@inproceedings{6426,
author = {{Müller, Ulrich}},
location = {{Paderborn}},
title = {{{Veredeln von Nahrungsmitteln}}},
year = {{2005}},
}
@inproceedings{6427,
author = {{Müller, Ulrich}},
keywords = {{Vortrag}},
location = {{Paderborn}},
title = {{{Prozess-Entwicklung}}},
year = {{2005}},
}
@inproceedings{6428,
author = {{Müller, Ulrich}},
location = {{Dortmund}},
title = {{{Die mechanische Entkeimung von festen Lebensmitteln mittels Sattdampf}}},
year = {{2005}},
}
@inproceedings{6429,
author = {{Jordan, V. and Müller, Ulrich}},
location = {{Breslau}},
title = {{{Surfactants and Dispersed Systems in Theory and Practice}}},
year = {{2005}},
}
@inproceedings{6430,
author = {{Müller, Ulrich and Meyer, T.}},
location = {{Bielefeld}},
title = {{{Zur Entwicklung einer mechanischen Entkeimungsmethode von Lebensmittel- und Arzneimitteln}}},
year = {{2005}},
}
@inproceedings{6431,
author = {{Müller, Ulrich and Wilhelm, Patrick and Giefers, C. and Lilie, M.}},
keywords = {{auch Reprint}},
location = {{Dresden}},
title = {{{Stand der Untersuchungen zur mechanischen Sattdampfentkeimung}}},
year = {{2005}},
}
@inproceedings{6432,
author = {{Wilhelm, Patrick and Giefers, C. and Lilie, M. and Müller, Ulrich}},
location = {{Dresden}},
title = {{{Kalkulation thermischer Abtötungseffekte – Unterstützung bei der Auslegung von Entkeimungsprozessen}}},
year = {{2005}},
}
@inproceedings{6433,
author = {{Müller, Ulrich and Chchtian, S. and Jordan, V. and Schlitter, K.}},
keywords = {{Poster}},
location = {{Dresden}},
title = {{{Zur Entwicklung einer Phytostoff-Tensid-Extraktion}}},
year = {{2005}},
}
@misc{12068,
author = {{Bruns, Christina and Kutz, Gerd and Wilms, J.}},
location = {{Nürnberg}},
title = {{{A new manufacturing process for ISDN retard pellets: feasibility studies and risk assessment}}},
year = {{2005}},
}
@misc{12069,
author = {{Kardel, M. and Kutz, Gerd and Rosito, R. and von Zydowitz, H. }},
location = {{Nürnberg}},
title = {{{Quality and economic efficiency of inspection methods}}},
year = {{2005}},
}
@misc{2347,
author = {{Frahm, Björn and Lane, Paul and Munack, Axel and Pörtner, Ralf}},
booktitle = {{Chemie Ingenieur Technik}},
issn = {{1522-2640}},
number = {{4}},
pages = {{429--435}},
publisher = {{WILEY-VCH Verlag}},
title = {{{Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode}}},
doi = {{10.1002/cite.200407094}},
volume = {{77}},
year = {{2005}},
}
@inbook{2443,
author = {{Upmann, Matthias}},
booktitle = {{Chemisches und Veteriäruntersuchungsamt CVUA-OWL : Jahresbericht 2005}},
title = {{{Salmonellen in Lebensmitteln}}},
year = {{2005}},
}
@inproceedings{2488,
author = {{Upmann, Matthias}},
location = {{Rheda-Wiedenbrück}},
title = {{{Rechtliche Beurteilung von vorverpacktem Fleisch und Fleischerzeugnissen}}},
year = {{2005}},
}
@inproceedings{2680,
author = {{Kutz, Gerd}},
location = {{Neuenburg}},
title = {{{Verfahren zur Bestimmung von Partikel- bzw. Tröpfchengrößen in Emulsionssystemen}}},
year = {{2005}},
}
@article{2718,
author = {{Kutz, Gerd and Henning, Sabine and Bruns, Christiane}},
journal = {{PZ Prisma - Pharmazeutische Zeitung}},
number = {{4}},
pages = {{219--227}},
title = {{{Neue Hilfsstoffe für Dermatika- Vom galenischen Rohstoff zum wertsteigernden Additiv}}},
volume = {{12}},
year = {{2005}},
}
@inproceedings{4221,
author = {{Kutz, Gerd and Salzmann, Volker and Bruns, Christina and Henning, S.}},
keywords = {{Scientific lecture}},
location = {{Nürnberg}},
title = {{{Feasibility studies on emulsion manufacturing using the Co-Twister processing facility}}},
year = {{2005}},
}
@inproceedings{4223,
author = {{Generotzky, F. and Hennig, S. and Kutz, Gerd}},
keywords = {{Scientific poster}},
location = {{Nürnberg}},
title = {{{Heat distribution and determination of cold spots within a stopper treatment and transfer unit}}},
year = {{2005}},
}
@inproceedings{4224,
author = {{Nierychlok, N. and Kutz, Gerd}},
keywords = {{Scientific poster}},
location = {{Nürnberg}},
title = {{{Implementation of a computerised system for the monitoring of storage conditions within the scope of stability testing}}},
year = {{2005}},
}
@inproceedings{4226,
author = {{Brenner, S. and Hellweg, E. and Kutz, Gerd}},
keywords = {{Scientific poster}},
location = {{Nürnberg}},
title = {{{Comparative validation studies on microbial collecctors to be used in isolator systems }}},
year = {{2005}},
}
@inproceedings{4227,
author = {{Generotzky, F. and Kutz, Gerd and Luenz, N.}},
keywords = {{Scientific poster}},
location = {{Nürnberg}},
title = {{{Investigations on the CIP-System of the Lyophilisator GT 6750}}},
year = {{2005}},
}
@inproceedings{4228,
author = {{Kutz, Gerd}},
keywords = {{Vortrag}},
location = {{Neuenburg }},
title = {{{Verfahren zur Bestimmung von Partikel- bzw. Tröpfchengrößen in Emulsionssystemen}}},
year = {{2005}},
}
@inproceedings{4230,
author = {{Kutz, Gerd}},
keywords = {{Vortrag}},
location = {{Detmold}},
title = {{{Neue Rohstoffe für die Formulierung von Emulsionen }}},
year = {{2005}},
}
@inproceedings{4474,
author = {{Kutz, Gerd}},
location = {{Fachhochschule Lippe und Höxter in Detmold}},
title = {{{Innovationskonzhepte in Hautpflegemitteln: Entwicklungstrends, Formulierungsstrategien, Charaktersisierung}}},
year = {{2005}},
}
@misc{9459,
author = {{Wilhelm, Patrick}},
booktitle = {{Lebensmitteltechnik}},
issn = {{0047-4290}},
number = {{37}},
pages = {{44 -- 45}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Gesunde Ernährung. GVC und Dechema mit fünf Vortragsblöcken für das Life Science Engineering.}}},
year = {{2005}},
}
@inbook{2756,
author = {{Müller, Ulrich}},
booktitle = {{AiF Forschungsreport 2005}},
pages = {{50--51}},
title = {{{Entwicklung und Untersuchung eines kontinuierlichen und eines quasikontinuierlichen Sattdampfentkeimungsverfahrens für zerkleinerte pflanzliche Materialien}}},
year = {{2005}},
}
@misc{2813,
author = {{Frahm, Björn and Pörtner, R.}},
booktitle = {{Animal Cell Technology Meets Genomics}},
isbn = {{1-4020-2791-5}},
location = {{Granada}},
pages = {{693--695}},
publisher = {{Springer}},
title = {{{Flexible Fed-Batch Process Control of Animal Cells}}},
doi = {{10.1007/1-4020-3103-3_142}},
volume = {{vol. 2}},
year = {{2005}},
}
@inbook{2831,
abstract = {{Kapitel V2}},
author = {{Müller, Ulrich and Lilie, Markus and Hein, Sven}},
booktitle = {{Handbuch Lebensmittelhygiene }},
title = {{{Physikalische Verfahren}}},
year = {{2005}},
}
@article{2840,
author = {{Stiebing, Achim and Müller, Ulrich and Hegerding, Lars and Wilhelm, Patrick}},
issn = {{0015-363X}},
journal = {{Fleischwirtschaft}},
number = {{3}},
pages = {{119--123}},
publisher = {{ Deutscher Fachverlag GmbH}},
title = {{{Dekontamination von Fleischoberflächen mittels Kurzzeitdampfverfahren - Entkeimungswirkung versus Vergrauung}}},
volume = {{85}},
year = {{2005}},
}
@misc{2907,
author = {{Pörtner, Ralf and Frahm, Björn and Lane, P. and Munack, A.}},
location = {{Harrogate, UK}},
title = {{{Optimisation of time-space-yield for hybridoma fed-batch cultures with an adaptive OLFO-controller}}},
year = {{2005}},
}
@misc{2908,
author = {{Pörtner, R. and Frahm, Björn and Hass, V. C. and Lane, P. and Munack, A.}},
location = {{Wiesbaden, Germany}},
title = {{{Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode}}},
year = {{2005}},
}
@inbook{3334,
author = {{Müller, Ulrich}},
booktitle = {{TRAFO Forschungsreport 2006}},
pages = {{154--155}},
title = {{{Entwicklung und Untersuchung eines kontinuierlichen und eines quasikontinuierlichen Sattdampfentkeimungsverfahrens für zerkleinertepflanzliche Materialien}}},
year = {{2005}},
}
@article{3446,
author = {{Schneider, Jan and Orzinski, Martin}},
journal = {{Brauindustrie}},
number = {{8}},
pages = {{48--52}},
title = {{{Mechanische Effekte bei Flaschenreinigungsmaschinen mit Geradstrahl- und Drehrohrspritzung : Exemplarische Studie}}},
volume = {{89}},
year = {{2005}},
}
@article{3523,
author = {{Schneider, Jan and Orzinski, Martin and Weber, Ingrid}},
journal = {{Technical quarterly & the MBAA communicator / Master Brewers Association of The Americas}},
number = {{4}},
pages = {{346--352}},
title = {{{New Requirements of the Measurements of Permeation Through Plastic Bottles and Closures}}},
volume = {{42}},
year = {{2005}},
}
@article{3532,
author = {{Schneider, Jan and Kunzmann, Christoph and Schildbach, Stefan and Ahrens, Alfons}},
journal = {{Brauwelt}},
number = {{21}},
pages = {{624}},
title = {{{Wasserrecycling bei der Flaschenreinigungsmaschine}}},
year = {{2005}},
}
@article{3533,
author = {{Schneider, Jan and Schröder, Gerhard and Kerwitz, Yvonne and Weber, Ingrid and Orzinski, Martin}},
journal = {{Brauwelt}},
number = {{51/52}},
pages = {{1642--1650}},
title = {{{Wirkung von Additiven auf die chemische und tribologische Glaskorrosion bei der Reinigung von Glasflaschen}}},
year = {{2005}},
}
@inbook{6198,
author = {{Müller, Ulrich and Fehlhaber, K. and Kleer, N.}},
booktitle = {{Handbuch der Lebensmittelhygiene}},
editor = {{Kley, F.}},
publisher = {{Behr`s Verlag}},
title = {{{Haltbarmachungsverfahren - physikalische Verfahren}}},
volume = {{Kap. V2}},
year = {{2005}},
}
@article{6230,
author = {{Herding, L. and Wilhelm, P. and Müller, Ulrich and Stiebing, Achim}},
journal = {{Fleischwirtschaft}},
number = {{3}},
pages = {{119--123}},
title = {{{Decontamination of meat surfaces by a short-time saturated steam process}}},
volume = {{85}},
year = {{2005}},
}
@inproceedings{6363,
author = {{Wilhelm, Patrick and Giefers, C. and Lilie, M. and Müller, Ulrich}},
keywords = {{Reprint}},
location = {{Dresden}},
title = {{{Kalkulation thermischer Abtötungseffekte – Unterstützung bei der Auslegung von Entkeimungsprozessen; Langfassung des Vortrages}}},
year = {{2005}},
}
@book{5495,
author = {{Fehlhaber, K. and Kleer, N. and Kley, F.}},
publisher = {{Behrs-Verlag}},
title = {{{Haltbarmachungsverfahren - physikalische Verfahren}}},
volume = {{Kap. V2}},
year = {{2005}},
}
@inproceedings{6412,
author = {{Giefers, C. and Müller, Ulrich and Brocklehurst, T.}},
location = {{Köthen}},
title = {{{Modelluntersuchungen zur Anhaftung von Salmonella Typhimurium LT 2 auf Gemüseoberflächen}}},
year = {{2004}},
}
@inproceedings{6413,
author = {{Hein, S. and Lilie, M. and Giefers, C. and Cuqat , D. and Müller, Ulrich}},
keywords = {{Poster}},
location = {{Köthen}},
title = {{{Produktschonende Entkeimung – Betrachtungen zur Veränderung des Gehaltes und der Zusammensetzung von ätherischen Ölen am Beispiel von schwarzem Pfeffer}}},
year = {{2004}},
}
@inproceedings{6414,
author = {{Müller, Ulrich and Lilie, M. and Wilhelm, Patrick}},
location = {{Universität Karlsruhe }},
title = {{{Mechanische Entkeimung – der Einsatz der Flashverdampfung für die Oberflächenentkeimung“, Vortrag beim Symposium „Höhere Qualität durch reinere Produkte“}}},
year = {{2004}},
}
@inproceedings{6415,
author = {{Jordan, V. and Müller, Ulrich}},
location = {{Frankfurt}},
title = {{{Extraktionen mit Systemen aus Tensid-Mesophasen – Potenziale für die Naturstoffisolierung}}},
year = {{2004}},
}
@inproceedings{6417,
author = {{Hein, S. and Müller, Ulrich and Lilie, M. and Wilhelm, Patrick and Giefers, C.}},
location = {{Lemgo}},
title = {{{Übersicht - Einordnung neuartiger Entkeimungsverfahren}}},
year = {{2004}},
}
@inproceedings{6418,
author = {{Müller, Ulrich and Lilie, M. and Wilhelm, Patrick and Giefers, C. and Hein, S.}},
location = {{Lemgo}},
title = {{{Grundlegendes zur Abtötung von vegetativen Keimen und bakteriellen Sporen}}},
year = {{2004}},
}
@inproceedings{6419,
author = {{Lilie, M. and Hein, S. and Wilhelm, Patrick and Giefers, C. and Müller, Ulrich}},
location = {{Lemgo}},
title = {{{Fortschritte beim Lemgoer Sattdampfentkeimungsverfahren}}},
year = {{2004}},
}
@misc{2345,
author = {{Pörtner, Ralf and Schwabe, Jan-Oliver and Frahm, Björn}},
booktitle = {{Biotechnology and Applied Biochemistry}},
issn = {{1470-8744}},
publisher = {{Wiley-Blackwell}},
title = {{{Evaluation of selected control strategies for fed-batch cultures of a hybridoma cell line}}},
doi = {{10.1042/ba20030168}},
volume = {{40}},
year = {{2004}},
}
@inproceedings{2359,
author = {{Becker, Barbara}},
title = {{{Lebensmittelassoziierte Viren - aktuelle Apekte}}},
year = {{2004}},
}
@misc{2409,
author = {{Upmann, Matthias and Wellm, G.}},
booktitle = {{Encyclopedia of meat sciences}},
editor = {{Jensen, Werner K.}},
isbn = {{0-12-464970-x}},
pages = {{1119--1129}},
publisher = {{Elsevier }},
title = {{{Quality management: Abattoirs and processing plants}}},
volume = {{3}},
year = {{2004}},
}
@misc{2410,
author = {{Upmann, Matthias and Stephan, R.}},
booktitle = {{Encyclopedia of meat sciences}},
editor = {{Jensen, Werner K.}},
isbn = {{0-12-464970-x}},
pages = {{667--674}},
publisher = {{Elsevier}},
title = {{{Laboratory accreditation}}},
volume = {{2}},
year = {{2004}},
}
@misc{2411,
author = {{Upmann, Matthias and Jakob, P.}},
booktitle = {{Encyclopedia of meat sciences}},
editor = {{Jensen, Werner K.}},
isbn = {{0-12-464970-x}},
pages = {{547--558}},
publisher = {{Elsevier}},
title = {{{HACCP and self-regulation}}},
volume = {{2}},
year = {{2004}},
}
@article{2451,
author = {{Schneider, Jan and Götz, Joachim and Först, Petra and Weisser, Horst}},
journal = {{Journal of American Society of Brewing Cheemists}},
number = {{1}},
pages = {{37--47}},
title = {{{A Comparative Nuclear Magnetic Resonance and Rheological Study on Mash and Spent Grain Suspensions, Worts, and Carbohydrate Solutions}}},
volume = {{61}},
year = {{2004}},
}
@inproceedings{4233,
author = {{Kutz, Gerd}},
keywords = {{Vortrag}},
location = {{Lemgo}},
title = {{{Qualifizierung und Validierung in der pharmazeutisch-betrieblichen Praxis}}},
year = {{2004}},
}
@article{4235,
author = {{Kutz, Gerd and Henning, S. and Rac, D. and Scheppler, P.}},
issn = {{0942-7694}},
journal = {{SÖFW-Journal : internationales Journal für angewandte Wissenschaft ; Kosmetik, Haushalt, Spezialprodukte }},
number = {{1/2}},
pages = {{35--44}},
publisher = {{Verl. für Chemische Industrie }},
title = {{{PEG/PPG-25/25 Dimethicone: Was leistet es? : Vom Dreikomonentendiagramm zu sensorisch überzeugenden und kosmetisch wirksamen Formulierungen}}},
volume = {{130}},
year = {{2004}},
}
@article{2739,
author = {{Kutz, Gerd and Nürnberg, E.}},
issn = {{0031-711X }},
journal = {{Pharmazeutische Industrie}},
publisher = {{Editio-Cantor-Verl. für Medizin und Naturwiss. }},
title = {{{Kollagen-Hydrolysate als pharmazeutische Hilfsstoffe. 2. Mitteilung}}},
year = {{2004}},
}
@article{2746,
author = {{Kutz, Gerd and Hennigs, Sören}},
issn = {{0016-3538}},
journal = {{GIT : Labor-Fachzeitschrift}},
number = {{9}},
pages = {{894 -- 896}},
publisher = {{Wiley-VCH Verlag }},
title = {{{Partikelgrößen in Pharmazie und Kosmetik}}},
volume = {{47}},
year = {{2004}},
}
@article{2838,
author = {{Müller, Ulrich and Lilie, Markus and Wilhelm, Patrick}},
issn = {{0009-286X}},
journal = {{Chemie-Ingenieur-Technik}},
number = {{10}},
pages = {{1602--1605}},
publisher = {{WILEY-VCH Verlag GmbH & Co. KGaA}},
title = {{{Mechanische Effekte bei der Sattdampfentkeimung}}},
doi = {{10.1002/cite.200403406}},
volume = {{76}},
year = {{2004}},
}
@article{3403,
author = {{Schneider, Jan and Orzinski, Martin and Weber, Ingrid}},
issn = {{1438-9452}},
journal = {{PET plant insider}},
number = {{5}},
pages = {{32--33}},
publisher = {{Heidelberg business media}},
title = {{{Capabilities in gas Permeation Measurement }}},
volume = {{9}},
year = {{2004}},
}
@article{3404,
author = {{Schneider, Jan and Lang, Michael and Keyser, Werner and Schreder, Marc}},
issn = {{0006-9736}},
journal = {{The new brewer international}},
number = {{2}},
pages = {{19--22}},
title = {{{The new brewhouse at Vereinsbrauerei Apolda}}},
volume = {{4}},
year = {{2004}},
}
@article{3405,
author = {{Schneider, Jan and Lang, Michael and Keyser, Werner and Schreder, Marc}},
issn = {{0179-2466}},
journal = {{Brauerei-Forum}},
number = {{10}},
pages = {{254--256}},
publisher = {{Versuchs- und Lehranstalt für Brauerei }},
title = {{{Das neue Sudhaus der Vereinsbrauerei in Apolda : Technisch-technologische Abnahme des neuen Sudhauses der Brauerei Apolda}}},
volume = {{19}},
year = {{2004}},
}
@article{3521,
author = {{Schneider, Jan and Weber, Ingrid and Orzinski, Martin}},
journal = {{Brauindustrie}},
number = {{11}},
pages = {{66--71}},
title = {{{Hohe Genauigkeit und gute Reproduzierbarkeit : Permeationsmessungen in der VLB Berlin}}},
volume = {{88}},
year = {{2004}},
}
@article{3525,
author = {{Schneider, Jan and Orzinski, Martin and Wuertz, Andreas and Garbe, Leif-A.}},
journal = {{Technical quarterly & the MBAA communicator}},
number = {{3}},
pages = {{190--197}},
title = {{{Permeation of Volatile Organic Compounds Through Plastic Bottles and Closuresin the Beverage Industry}}},
volume = {{44}},
year = {{2004}},
}
@article{3526,
author = {{Schneider, Jan and Weisser, Horst}},
journal = {{Journal of the Institute of Brewing}},
number = {{4}},
pages = {{326--334}},
title = {{{Diafiltration of Mash}}},
volume = {{110}},
year = {{2004}},
}
@article{3527,
author = {{Schneider, Jan and Manger, Hans-J.}},
journal = {{Brauindustrie}},
number = {{11}},
pages = {{63--67}},
title = {{{Ist die Luft rein? : Raumlufttechnische Anlagen in Brauereien mit besonderer Betrachtung der Abfüllung}}},
volume = {{91}},
year = {{2004}},
}
@article{3528,
author = {{Schneider, Jan and Weber, Ingrid and Orzinski, Martin}},
journal = {{Brauerei-Forum}},
number = {{3}},
pages = {{61--63}},
title = {{{Aufbau des Kompetenzbereiches "Kunststoffflaschen und Permeationsmessungen"an der VLB Berlin : Anforderungen und Möglichkeiten der Beurteilung von O2- und CO2- Barrierenvon Kunststofffl aschen und -verschlüssen}}},
volume = {{20}},
year = {{2004}},
}
@inproceedings{6359,
author = {{Müller, Ulrich and Wilhelm, Patrick and Barbe, St. and Lilie, M.}},
location = {{Montpellier/F}},
title = {{{Mechanical decontamination effects during a steam treatment of foods}}},
year = {{2004}},
}
@inproceedings{6362,
author = {{Wilhelm, Patrick and Lilie, M. and Barbe, St. and Müller, Ulrich}},
location = {{Nürnberg}},
title = {{{Mild steam-decontamination of drugs and other plant material using mechanical effects}}},
year = {{2004}},
}
@inproceedings{6407,
author = {{Müller, Ulrich and Wilhelm, Patrick and Barbe, St. and Lilie, M.}},
keywords = {{Poster}},
location = {{Montepellier/F}},
title = {{{Mechanical decontamination effects during a steam treatment of foods}}},
year = {{2004}},
}
@inproceedings{6409,
author = {{Wilhelm, Patrick and Lilie, M. and Barbe, S. and Müller, Ulrich}},
location = {{Nürnberg}},
title = {{{Mild steam-decontamination of drugs and other plant material using mechanical efffects}}},
year = {{2004}},
}
@inproceedings{6411,
author = {{Lilie, M. and Wilhelm, Patrick and Giefers, C. and Müller, Ulrich and Cuqat, D.}},
location = {{Köthen}},
title = {{{Fortschritte bei der Anwendung der Flash-Verdampfung für die mechanische Entkeimung von (Lebensmittel-)oberflächen}}},
year = {{2004}},
}
@misc{7934,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Manchester, UK}},
title = {{{Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies}}},
year = {{2003}},
}
@misc{11505,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Produktbeschreibende physikalisch-chemische Verfahren inkl. „in situ“ und „online“ Partikelgrößenbestimmung mittels Lasertechnologie}}},
year = {{2003}},
}
@misc{11506,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Hautpflegemittel: Formulierungsstrategien, Entwicklungstrends, Charakterisierung}}},
year = {{2003}},
}
@misc{2343,
author = {{Frahm, Björn and Hass, V. C. and Lane, P. and Munack, A. and Märkl, H. and Pörtner, R.}},
booktitle = {{Chemie Ingenieur Technik}},
issn = {{1522-2640}},
number = {{4}},
pages = {{457--460}},
publisher = {{WILEY-VCH Verlag}},
title = {{{Fed-Batch-Kultivierung tierischer Zellen - Eine Herausforderung zur adaptiven, modellbasierten Steuerung}}},
doi = {{10.1002/cite.200390093}},
volume = {{75}},
year = {{2003}},
}
@misc{2344,
author = {{Frahm, Björn and Lane, P. and Märkl, H. and Pörtner, R.}},
booktitle = {{Bioprocess and Biosystems Engineering}},
issn = {{1615-7591}},
number = {{1}},
pages = {{1--10}},
publisher = {{Springer}},
title = {{{Improvement of a mammalian cell culture process by adaptive, model-based dialysis fed-batch cultivation and suppression of apoptosis}}},
doi = {{10.1007/s00449-003-0335-z}},
volume = {{26}},
year = {{2003}},
}
@phdthesis{2393,
abstract = {{Die wirtschaftlich immer mehr an Bedeutung gewinnende Kultivierung tierischer Zelllinien umfasst zahlreiche Anwendungen in der Pharmaherstellung und Medizintechnik. Eine Vielzahl der Produkte (Diagnostika, Impfstoffe, Therapeutika) wird in Fed-Batch-Prozessen hergestellt. Für die verbesserte Steuerung von derartigen Fed-Batch-Prozessen stellt der Autor eine adaptive, modellgestützte Steuerung vor. Anwendungsbeispiele veranschaulichen das Potential und die Flexibilität der Steuerung und ihre Universalität bezüglich verschiedener Kultivierungssysteme und Zelllinien.
Da auch die gelöst-CO2-Konzentration und die Atmungsaktivität der Zellen zunehmend Bedeutung in der Prozessführung erlangen, stellt dieses Buch weiterhin die entwickelte Erfassung dieser Größen per Abgasanalytik und Modellierung des Kohlendioxidtransfers vor.}},
author = {{Frahm, Björn}},
isbn = {{ 978-3-8334-0111-4 }},
keywords = {{Tierzelle, Suspensionskultur, Prozesssteuerung}},
pages = {{120}},
publisher = {{Books on Demand GmbH}},
title = {{{Adaptive, modellgestützte Prozessführung von Suspensionskulturen tierischer Zellen}}},
year = {{2003}},
}
@misc{2435,
author = {{Frahm, Björn and Müller-Landré, B. and Wiggers de Almeida, G. and Singer, M. and Rausch, M. and Lane, P. and Munack, A. and Hass, V. C. and Pörtner, R.}},
booktitle = {{Technische Systeme für Biotechnologie und Umwelt}},
editor = {{Beckmann, Dieter}},
isbn = {{3-00-011287-1}},
location = {{Heilbad Heiligenstadt}},
pages = {{503--509}},
publisher = {{Inst. für Bioprozess- und Analysenmesstechnik }},
title = {{{Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control}}},
year = {{2003}},
}
@misc{2436,
author = {{Kühn, K. and Frahm, Björn and Pörtner, R. and Lane, P. and Munack, A. and Hass, V. C.}},
booktitle = {{ ECCE - 4th European Congress of Chemical Engineering}},
isbn = {{84-88233-35-3}},
location = {{Granada}},
publisher = {{ECCE4}},
title = {{{Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells}}},
volume = {{10}},
year = {{2003}},
}
@inproceedings{2901,
author = {{Pörtner, R. and Frahm, Björn}},
location = {{Manchester, UK}},
title = {{{Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies}}},
year = {{2003}},
}
@misc{2902,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Göttingen, Germany}},
title = {{{Fed-Batch-Kultivierungen tierischer Zellen – eine Herausforderung an eine modellgestützte, adaptive Steuerung}}},
year = {{2003}},
}
@misc{2903,
author = {{Hass, V. C. and Kühn, K. and Frahm, Björn and Pörtner, R. and Lane, P. and Munack, A.}},
location = {{München}},
title = {{{Ein strukturiertes Kompartiment-Modell zur Beschreibung der Kultivierung von Hybridomazellen als Teil einer adaptiven, modellgestützten Prozessführung}}},
year = {{2003}},
}
@misc{2905,
author = {{Frahm, Björn and Lane, P. and Munack, A. and Hass, V. C. and Pörtner, Ralf}},
location = {{Frankfurt am Main, Germany}},
title = {{{Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies}}},
year = {{2003}},
}
@misc{2906,
author = {{Pörtner, Ralf and Frahm, Björn and Lane, P. and Hass, V. C. and Munack, A. and Märkl, H.}},
location = {{Bad Dürkheim, Germany}},
title = {{{Fed-Batch-Kultivierung tierischer Zellen – eine Herausforderung für eine adaptive, modellgestützte Steuerung}}},
year = {{2003}},
}
@misc{2964,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Manchester, UK}},
title = {{{CO2-off-gas measurement for animal cell culture processes}}},
year = {{2003}},
}
@misc{2965,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Granada, Spain}},
title = {{{Flexible fed-batch process control of animal cells}}},
year = {{2003}},
}
@misc{2966,
author = {{Kühn, K. and Frahm, Björn and Pörtner, Ralf and Lane, P. and Munack, A. and Hass, V. C.}},
location = {{Granada, Spain}},
title = {{{Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells}}},
year = {{2003}},
}
@book{3354,
editor = {{Müller, Ulrich and Kurzhals, Hans-Albert}},
pages = {{IX, 691}},
publisher = {{Behr}},
title = {{{Lexikon Lebensmitteltechnik}}},
volume = {{2}},
year = {{2003}},
}
@inbook{3443,
abstract = {{Kapitel 11}},
author = {{Schneider, Jan}},
booktitle = {{Symposium Sanitary Enginering & HACCP}},
isbn = {{3-418-00796-1}},
title = {{{Qualification in engineering and construction of production plants}}},
year = {{2003}},
}
@inbook{6197,
author = {{Figura, L. and Kleinschmidt, T. and Kluge, C. and Linke, L. and Müller, Ulrich and Schallenberg, J. and Scherer, R.}},
booktitle = {{?}},
editor = {{Kurzhals, H.-A.}},
publisher = {{Behr`s Verlag}},
title = {{{Lexikon Lebensmitteltechnik}}},
volume = {{Bd 1 (A-K9 Bd 2 (L-Z)}},
year = {{2003}},
}
@inproceedings{6402,
author = {{Wilhelm, Patrick and Müller, Ulrich}},
location = {{Freising}},
title = {{{Schonende Entkeimung mit dem Lemgoer Entkeimungsverfahren am Beispiel von Fleischoberflächen}}},
year = {{2003}},
}
@inproceedings{6403,
author = {{Wilhelm, Patrick and Müller, Ulrich}},
location = {{Stuttgart-Hohenheim}},
title = {{{Mechanische Effekte bei der Entkeimung von Lebensmitteln mit dem Lemgoer Entkeimungsverfahren}}},
year = {{2003}},
}
@inproceedings{6404,
author = {{Lilie, M. and Wilhelm, Patrick and Müller, Ulrich}},
location = {{Stuttgart-Hohenheim}},
title = {{{Lemgoer Sattdampfverfahren – Ansätze einer Reinigungstechnik für Oberflächen}}},
year = {{2003}},
}
@inproceedings{6405,
author = {{Wilhelm, Patrick and Müller, Ulrich and Barbe, St. and Lilie, M.}},
location = {{Norwich/UK}},
title = {{{Mechanical Components in the Decontamination of B. subtilis and L. plantarum on Various Surfaces – A Progress Report}}},
year = {{2003}},
}
@inproceedings{6406,
author = {{Wilhelm, Patrick and Müller, Ulrich and Barbe, St. and Lilie, M.}},
location = {{Lemgo}},
title = {{{Mechanische Effekte bei der Sattdampfentkeimung von B. subtilis und L. plantarum auf verschiedenen Oberflächen}}},
year = {{2003}},
}
@misc{11507,
author = {{Kutz, Gerd}},
location = {{Krefeld}},
title = {{{Herstellung von Hautpflegemitteln}}},
year = {{2002}},
}
@misc{2340,
author = {{Frahm, Björn and Blank, H.-C. and Cornand, P. and Oelßner, W. and Guth, U. and Lane, P. and Munack, A. and Johannsen, K. and Pörtner, R.}},
booktitle = {{Journal of Biotechnology}},
issn = {{1873-4863 }},
keywords = {{Dissolved carbon dioxide, Carbon dioxide production rate, Carbon dioxide transfer rate, Off-gas measurement, Mammalian cell suspension culture}},
number = {{2}},
pages = {{133--148}},
publisher = {{Elsevier}},
title = {{{Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement}}},
doi = {{https://doi.org/10.1016/S0168-1656(02)00180-3}},
volume = {{99}},
year = {{2002}},
}
@misc{2341,
author = {{Frahm, Björn and Lane, P. and Atzert, H. and Munack, A. and Hoffmann, M. and Hass, V. C. and Pörtner, R.}},
booktitle = {{Biotechnology Progress}},
issn = {{1520-6033}},
number = {{5}},
pages = {{1095--1103}},
publisher = {{ Wiley }},
title = {{{Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Effective Fed-Batch Cultivation of Hybridoma Cells}}},
doi = {{10.1021/bp020035y}},
volume = {{18}},
year = {{2002}},
}
@misc{2342,
author = {{Frahm, Björn and Pörtner, R.}},
booktitle = {{BIOforum}},
issn = {{0940-0079}},
pages = {{179--180}},
publisher = {{GIT-Verlag}},
title = {{{Reaktor-Abgasmessungen bei Zellkulturen}}},
volume = {{4}},
year = {{2002}},
}
@misc{2431,
author = {{Frahm, Björn and Pörtner, Ralf}},
booktitle = {{Biosystemtechnik: Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung biotechnologischer Prozesse}},
editor = {{Kaden , Heiner }},
isbn = {{3-00-009026-6}},
location = {{Waldheim/Sa. }},
pages = {{39--48}},
publisher = {{Kurt-Schwabe-Inst. }},
title = {{{Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen}}},
year = {{2002}},
}
@inbook{2452,
author = {{Upmann, Matthias and Wellm, Gabriele and Pollinger, Sandra}},
booktitle = {{43. Arbeitstagung dess Arbeitsgebietes Lebensmittelhygiene}},
location = {{Garmisch-Partenkirchen }},
pages = {{797--802}},
title = {{{Einfluss eines aeroben und eines aneroben Transportmediums auf die Wiedererfindungsrate von Escherichja coli, Pseudomonas Putida und Bifidobacterium Pseudolongum beim Nass-Trocken-Tupferverfahen von Arbeitsflächen}}},
year = {{2002}},
}
@inbook{2453,
author = {{Upmann, Matthias and Kopeinig, Katharina and Bonaparte, Christine and Kneifel, W.}},
booktitle = {{43. Arbeitstagung dess Arbeitsgebietes Lebensmittelhygiene}},
location = {{Garmisch-Partenkirchen }},
pages = {{658--663}},
title = {{{Selektiver Nachweis von Bifidobakterien mit Hilfe eines Mupircin-Haltigen Nährbodens}}},
year = {{2002}},
}
@inbook{2454,
author = {{Upmann, Matthias and Kopeinig, Katharina and Pollinger, Sandra and Wellm, Gabriele and Gavani, Francoise}},
booktitle = {{43. Arbeitstagung dess Arbeitsgebietes Lebensmittelhygiene}},
location = {{Garmisch-Partenkirchen }},
pages = {{286--291}},
title = {{{Vorkommen von Bifidobakterienstämmen in der Rindfleischproduktionskette}}},
year = {{2002}},
}
@inbook{2455,
author = {{Upmann, Matthias and Pollinger, Sandra and Kopeinig, Katharina and Wellm, Gabriele}},
booktitle = {{43. Arbeitstagung dess Arbeitsgebietes Lebensmittelhygiene}},
location = {{Garmisch-Partenkirchen }},
pages = {{292--297}},
title = {{{Vorkommen von Bifidobaterien im Vergleich zu aeroben Gesamtkeimzahl, Enterobakteriazeenzahl und der Escherichia Coli-Anzahl bei der Schweineschlachtung}}},
year = {{2002}},
}
@inbook{2456,
author = {{Upmann, Matthias and Novak, J.}},
booktitle = {{43. Arbeitstagung dess Arbeitsgebietes Lebensmittelhygiene}},
location = {{Garmisch-Partenkirchen }},
pages = {{747--752}},
title = {{{Einfluss des Autoklavierens auf die antimikrobielle Wirksamkeit von Oregano (Organumsp.) und Tymian (Thymus Vulgaris)}}},
year = {{2002}},
}
@inproceedings{2487,
author = {{Upmann, Matthias and Novak, J.}},
location = {{Garmisch-Partenkirchen}},
title = {{{Einfluss des Autoklavierens auf die antimikrobielle Wirksamkeit von Oregano (Orignanum sp.) und Thymian (Thymus vulgaris)}}},
year = {{2002}},
}
@misc{9444,
author = {{Wilhelm, Patrick}},
booktitle = {{Lebensmitteltechnik}},
issn = {{0047-4290}},
number = {{9}},
pages = {{46}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Breites Themenspektrum. GVC und Dechema tagten gemeinsam in den Wiesbadener Rhein-Main-Hallen}}},
year = {{2002}},
}
@misc{2897,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Wiesbaden, Germany}},
title = {{{Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen}}},
year = {{2002}},
}
@misc{2898,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Lonza Biologics, Slough, UK}},
title = {{{Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells}}},
year = {{2002}},
}
@misc{2899,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Birmingham, UK}},
title = {{{Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells}}},
year = {{2002}},
}
@misc{2900,
author = {{Frahm, Björn and Müller-Landré, B. and Wiggers de Almeida, G. and Singer, M. and Rausch, M. and Lane, P. and Munack, A. and Hass, V. C. and Pörtner, R.}},
location = {{Heilbad Heiligenstadt, Germany}},
title = {{{Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control}}},
year = {{2002}},
}
@inproceedings{3351,
author = {{Müller, Ulrich and Kohlus, R.}},
location = {{Sydney, Australia}},
title = {{{Steam enhanced centrifugation}}},
year = {{2002}},
}
@article{6357,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
issn = {{0047-4290}},
journal = {{Lebensmitteltechnik}},
number = {{9}},
pages = {{58--59}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Mechanische Entkeimung - geringe Wassersattdampftemperaturen bieten schonende Möglichkeiten}}},
year = {{2002}},
}
@inproceedings{6358,
author = {{Müller, Ulrich and Wilhelm, Patrick}},
location = {{Gießen}},
title = {{{Schonende Sattdampfentkeimung von pflanzlichen Materialien mit dem Lemgoer Sattdampfentkeimungsverfahren}}},
year = {{2002}},
}
@inproceedings{6398,
author = {{Müller, Ulrich}},
location = {{Jena}},
title = {{{Vorstellung eines Sichtzellenautoklaven zur Untersuchung der Entkeimung mit Dampf}}},
year = {{2002}},
}
@inproceedings{6399,
author = {{Wilhelm, Patrick and Barbe, St. and Müller, Ulrich}},
location = {{Weimar}},
title = {{{Untersuchung nicht-thermischer Entkeimungseffekte bei der Sattdampfbehandlung von Modelloberflächen mit den Beispielen B. subtilis und L. plantarum}}},
year = {{2002}},
}
@inproceedings{6400,
author = {{Wilhelm, Patrick and Müller, Ulrich and Barbe, St.}},
location = {{Bernburg}},
title = {{{Mechanische Wirkungen beim Lemgoer Sattdampfentkeimungsverfahren}}},
year = {{2002}},
}
@inproceedings{6401,
author = {{Müller, Ulrich and Wilhelm, Patrick and Barbe, St.}},
location = {{Gießen}},
title = {{{Schonende Sattdampfentkeimung von pflanzlichen Materialien mit dem Lemgoer Sattdampfentkeimungsverfahren}}},
year = {{2002}},
}
@misc{7933,
author = {{Frahm, Björn and Pörtner, Ralf}},
location = {{Waldheim, Germany}},
title = {{{Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen}}},
year = {{2001}},
}
@misc{11508,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Herstellung und Qualitatssicherung von Hautpflegemitteln }}},
year = {{2001}},
}
@misc{2427,
author = {{Frahm, Björn and Atzert, H. and Lane, P. and Hoffmann, M. and Hass, V. C. and Munack, A. and Pörtner, Ralf}},
booktitle = {{Animal Cell Technology: From Target to Market}},
isbn = {{9789401038973}},
pages = {{446--448}},
publisher = {{Springer}},
title = {{{Development of an Automated, Adaptive Model-Based Control for the Effective Cultivation of Hybridoma Cells}}},
doi = {{10.1007/978-94-010-0369-8_107}},
volume = {{vol. 1}},
year = {{2001}},
}
@misc{2429,
author = {{Hass, V. C. and Lane, P. and Hoffmann, M. and Frahm, Björn and Schwabe, J.-O. and Pörtner, R. and Munack, A.}},
location = {{Québec City, Québec, Canada}},
title = {{{Model-Based Control of Hybridoma Cell Cultures}}},
year = {{2001}},
}
@inbook{2446,
author = {{Upmann, Matthias}},
booktitle = {{Qualitätssicherung in der mikrobiologischen Lebensmitteluntersuchung }},
editor = {{Paulsen, Peter}},
isbn = {{3-901950-03-6 }},
location = {{Wien}},
pages = {{14--15}},
publisher = {{Inst. für Fleischhygiene }},
title = {{{Schnellmethoden und Qualitätssicherung - eine Unvereinbarkeit?}}},
year = {{2001}},
}
@article{2447,
author = {{Upmann, Matthias and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft International}},
number = {{1}},
pages = {{33--34}},
title = {{{Reduction of the microbial contamination on fresh meat : 2. Microbial contral at slaughter and processing }}},
year = {{2001}},
}
@article{2449,
author = {{Upmann, Matthias and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft International}},
number = {{2}},
pages = {{57--59}},
title = {{{Reduction of the microbial contamination on fresh meat: 3: "Thid Line" intervention strategies: The decontamination issue}}},
year = {{2001}},
}
@inbook{2457,
author = {{Upmann, Matthias and Novak, J.}},
booktitle = {{42. Arbeitstagung dess Arbeitsgebietes Lebensmittelhygiene}},
location = {{Garmisch-Partenkirchen }},
pages = {{471--176}},
title = {{{Antimikrobielle Wirksamkeit von gerbeltem und gemahlenem Oregano sowie Oregano-Öl in Zubereitungen aus Hackfleisch}}},
year = {{2001}},
}
@article{2461,
author = {{Upmann, Matthias and Buckenhuskes, H.J.}},
journal = {{ernährung/nutrition}},
number = {{7/8}},
pages = {{300--311}},
title = {{{Qualitätssicherungskonzepte entlang der Fleischproduktionskette.}}},
volume = {{25}},
year = {{2001}},
}
@inproceedings{2465,
author = {{Upmann, Matthias and Stiegler, S. and Novak, J. and Krüger, G.}},
booktitle = {{Arbeitstagung des Arbeitsgebietes "Lebensmittelhygiene"}},
isbn = {{3-930511-93-2}},
location = {{ Garmisch-Partenkirchen}},
pages = {{324--329}},
title = {{{Einfluß von gerebeltem Oregano, Thymian, Rosmarin und Majoran auf die Entwicklung der Verderbnisflora in Zubereitung aus Hackfleisch}}},
year = {{2001}},
}
@inproceedings{2481,
author = {{Upmann, Matthias}},
location = {{Lissabon}},
title = {{{Microbial contamination sources in the meat cutting sector}}},
year = {{2001}},
}
@article{2482,
author = {{Upmann, Matthias and Buckenhuskes, H.J.}},
journal = {{METE}},
title = {{{Qualitätssicherungskonzepte entlang der Fleischproduktionskette}}},
year = {{2001}},
}
@inproceedings{2483,
author = {{Upmann, Matthias and Novak, J.}},
location = {{Garmisch-Partenkirchen }},
title = {{{Antimikrobielle Wirksamkeit von gerebeltem und gemahlenem Oregano sowie Oregano-Öl in Zubereitungen aus Hackfleisch}}},
year = {{2001}},
}
@inproceedings{2484,
author = {{Upmann, Matthias and Stiegler, S. and Novak, J.}},
location = {{Krakau (Polen)}},
title = {{{Effect of some spices on the development of the spoilage flora in minced meat preparations}}},
year = {{2001}},
}
@inbook{2485,
author = {{Upmann, Matthias and Stiegler, S. and Novak, J.}},
booktitle = {{Proc. 47. ICoMST}},
location = {{Krakau (Polen)}},
pages = {{38--39}},
title = {{{Effect of some spices on the development of the spoilage flora in minced meat preparations}}},
year = {{2001}},
}
@inproceedings{2486,
author = {{Upmann, Matthias}},
location = {{Wien}},
title = {{{Schnellmethoden und Qualitätssicherung – eine Unvereinbarkeit?}}},
year = {{2001}},
}
@book{4279,
author = {{Kutz, Gerd and Frieß, Stefan and Henning, sabine and Lünz, Nicole}},
isbn = {{978-3-87846-224-8 }},
publisher = {{Verlag für chemische Industrie H. Ziolkowsky Gmbh}},
title = {{{Kosmetische Emulsionen und Cremes - Formulierung, Herstellung, Prüfung }}},
year = {{2001}},
}
@book{4280,
author = {{Kutz, Gerd}},
isbn = {{5-901 100-19-0}},
publisher = {{Clavel Publishing Company Cosmetics & Medicine}},
title = {{{Kosmetische Emulsionen und Cremes - Formulierung, Herstellung, Prüfung - Russische Übersetzung}}},
year = {{2001}},
}
@inproceedings{4477,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Moderne Hautpflegemittel: Entwicklung, Herstellung und Prüfung}}},
year = {{2001}},
}
@misc{9443,
author = {{Wilhelm, Patrick}},
booktitle = {{Lebensmitteltechnik}},
issn = {{0047-4290}},
number = {{9}},
pages = {{51}},
publisher = {{LT Food Medien-Verlag GmbH}},
title = {{{Treffen der Chemieingenieure. Auch die Lebensmitteltechnologie war einbezogen.}}},
year = {{2001}},
}
@inproceedings{2828,
author = {{Müller, Ulrich and Czwalinna, R. and Lehre, Gerhard and Wilhelm, Patrick}},
location = {{Berlin}},
pages = {{453}},
title = {{{Vergleich zweier Gefrierverfahren von Stutenmilch hinsichtlich der anschließenden Vakuumgefriertrocknung}}},
year = {{2001}},
}
@misc{2894,
author = {{Hoffmann, M. and Hass, V. C. and Frahm, Björn and Schwabe, J.-O. and Pörtner, R. and Lane, P. and Munack, A.}},
location = {{Leipzig, Germany}},
title = {{{Untersuchung verschiedener mathematischer Modelle in Hinblick auf ihre Eignung für die adaptive Prozessführung von Hybridoma Zellkulturen}}},
year = {{2001}},
}
@misc{2895,
author = {{Frahm, Björn and Pörtner, R.}},
location = {{Hannover}},
title = {{{Arbeitsschwerpunkte TUHH, Bioprozess- und Bioverfahrenstechnik, Arbeitsgruppe Zellkulturtechnik}}},
year = {{2001}},
}
@misc{2960,
author = {{Frahm, Björn and Atzert, H. and Schwabe, J.-O. and Lane, P. and Munack, A. and Hoffmann, M. and Hass, V. C. and Pörtner, R.}},
location = {{Leipzig, Germany}},
title = {{{Adaptive modellgestützte Steuerung von Zellkulturprozessen}}},
year = {{2001}},
}
@misc{2961,
author = {{Lane, P. and Frahm, Björn and Atzert, H. and Schwabe, J.-O. and Hoffmann, M. and Hass, V. C. and Pörtner, R.}},
location = {{Leipzig, Germany}},
title = {{{Design of Feeding Strategies for Fed-Batch Cultures of Animal Cells by the Method of Inequalities}}},
year = {{2001}},
}
@misc{2962,
author = {{Frahm, Björn and Atzert, H. and Lane, P. and Hoffmann, M. and Hass, V. C. and Munack, A. and Pörtner, R.}},
location = {{Tylösand, Sweden}},
title = {{{Development of an automated, model-based, adaptive control for the effective cultivation of hybridoma cells}}},
year = {{2001}},
}
@misc{2963,
author = {{Hass, V.C. and Lane, P. and Hoffmann, M. and Frahm, Björn and Schwabe, J.-O. and Pörtner, R. and Munack, A.}},
booktitle = {{Computer Applications in Biotechnology, 2001: Modelling, Monitoring and Control of Biotechnological Processes}},
isbn = {{ 0080436811 }},
issn = {{ 1474-6670 }},
location = {{Québec City, Québec, Canada}},
pages = {{323--329}},
publisher = {{ScienceDirect}},
title = {{{Model-Based Control of Hybridoma Cell Cultures}}},
doi = {{https://doi.org/10.1016/S1474-6670(17)34240-4}},
volume = {{34}},
year = {{2001}},
}
@inproceedings{3348,
author = {{Müller, Ulrich and Wilhelm, Patrick and Lehre, G.}},
location = {{Berlin}},
title = {{{Nichtthermische Entkeimungseffekte bei der Sattdampfbehandlung von Oberflächen }}},
year = {{2001}},
}
@inproceedings{6356,
author = {{Czwalinna, R. and Wilhelm, Patrick and Lehre, Gerhard and Müller, Ulrich}},
keywords = {{GDL e. V., Bonn, (ISDN 3-931678-04-0)}},
location = {{Berlin}},
title = {{{Vergleich zweier Gefrierverfahren von Stutenmilch hinsichtlich der anschließenden Vakuumgefriertrocknung, Kurzfassung}}},
year = {{2001}},
}
@inproceedings{6396,
author = {{Müller, Ulrich}},
location = {{Bochum}},
title = {{{Überlegungen zur Planung von Produktionsprozessen in der Ernährungsindustrie}}},
year = {{2001}},
}
@inproceedings{6397,
author = {{Müller, Ulrich}},
location = {{Dortmund}},
title = {{{Von der Produkt- zur Prozessinnovation}}},
year = {{2001}},
}
@misc{11509,
author = {{Kutz, Gerd}},
location = {{Detmold}},
title = {{{Moderne Hautpflegemittel: Entwicklung, Herstellung und Prüfung}}},
year = {{2000}},
}
@article{2414,
author = {{Upmann, Matthias and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{27--29}},
title = {{{Verminderung der bakteriellen Belastung auf frischem Fleisch. III: Weitere Möglichkeiten zur Beeinflussung der Frischfleischflora}}},
volume = {{80}},
year = {{2000}},
}
@article{2415,
author = {{Upmann, Matthias and Smulders, Frans J.M.}},
journal = {{Reduction of bacterial contamination of fresh meat. II. Control of microbiological risks in meat production and processing.}},
number = {{10}},
pages = {{18--20}},
title = {{{Verminderung der bakteriellen Belastung auf frischem Fleisch. II: Beherrschung mikrobieller Risiken bei Fleischgewinnung und -bearbeitung }}},
volume = {{80}},
year = {{2000}},
}
@article{2416,
author = {{Upmann, Matthias and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft}},
number = {{9}},
pages = {{32--35}},
title = {{{Verminderung der bakteriellen Belastung auf frischem Fleisch. I: Beherrschung mikrobieller Risiken in Tierprodukten und Tiertransport}}},
volume = {{80}},
year = {{2000}},
}
@article{2417,
author = {{Upmann, Matthias and Smulders, Frans J.M. and James, Christian and Paulsen, Peter}},
journal = {{Fleischwirtschaft}},
number = {{8}},
pages = {{90--97}},
title = {{{Die Mirkobiologie von Kälte behandeltem Fleisch}}},
volume = {{80}},
year = {{2000}},
}
@misc{2421,
author = {{Upmann, Matthias and Bonaparte, C.}},
booktitle = {{Encyclopedia of food microbiology}},
editor = {{Robinson, Richard}},
isbn = {{0-12-227070-3}},
pages = {{1887--1895}},
publisher = {{Acad. Press}},
title = {{{Rapid methods for food hygiene inspection}}},
year = {{2000}},
}
@article{2434,
author = {{Upmann, Matthias and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft International}},
pages = {{29--32}},
title = {{{Reduction of the microbial contamination on fresh meat: 1. Microbial control at the farm and during transport}}},
volume = {{4}},
year = {{2000}},
}
@article{2448,
author = {{Upmann, Matthias and Paulsen, Peter and James, Christian and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft International}},
number = {{3}},
pages = {{38--45}},
title = {{{The Microbiology of refrigerated meat}}},
year = {{2000}},
}
@article{2450,
author = {{Upmann, Matthias and Paulsen, Peter and James, Christian and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft International}},
number = {{3}},
pages = {{38--45}},
title = {{{Microbiology of refrigerated meat}}},
year = {{2000}},
}
@article{2464,
author = {{Upmann, Matthias and Jakob, Peter and Reuter, Gerhard}},
journal = {{Dairy, Food and Environmental Sanitation}},
number = {{1}},
pages = {{14--23}},
title = {{{Microbial Transfer During Cutting and Deboning of Pork in a Small-Scale Meat Processing Plant}}},
volume = {{20}},
year = {{2000}},
}
@article{2476,
author = {{Upmann, Matthias and Smulders, Frans J.M.}},
journal = {{Fleischwirtschaft}},
number = {{11}},
pages = {{27--29}},
title = {{{Verminderung der bakteriellen Belastung auf frischem Fleisch. 3. Weitere Möglichkeiten zur Beeinflussung der Fleischflora}}},
volume = {{80}},
year = {{2000}},
}
@inproceedings{2477,
author = {{Upmann, Matthias}},
location = {{Bekescsaba (Ungarn)}},
title = {{{Qualitätssicherungskonzepte enttlang der Fleischproduktionskette}}},
year = {{2000}},
}
@inproceedings{2478,
author = {{Upmann, Matthias}},
booktitle = {{Proc. Internationales Symposium: Technologie der Salami- und Rohwurstherstellung sowie der Gänseverarbeitung}},
location = {{Bekescsaba (Ungarn)}},
pages = {{10}},
title = {{{Qualitätssicherungskonzepte entlang der Fleischproduktionskette}}},
year = {{2000}},
}
@inproceedings{2479,
author = {{Upmann, Matthias and Stiegler, S. and Novak, J. and Krüger, G.}},
location = {{ Garmisch-Partenkirchen}},
title = {{{Einfluß von gerebeltem Oregano, Thymian, Rosmarin und Majoran auf die Entwicklung der Verderbnisflora in Zubereitungen aus Hackfleisch}}},
year = {{2000}},
}
@inbook{2480,
author = {{Upmann, Matthias and Stiegler, S. and Novak, J. and Krüger, G.}},
booktitle = {{Proc. 41. Arbeitstagung des Arbeitsgebietes "Lebensmittelhygiene"}},
location = {{Garmisch-Partenkirchen}},
pages = {{324--329}},
title = {{{Einfluß von gerebeltem Oregano, Thymian, Rosmarin und Majoran auf die Entwicklung der Verderbnisflora in Zubereitungen aus Hackfleisch}}},
year = {{2000}},
}
@misc{2893,
author = {{Anderelei, T. and Frahm, Björn and Büchs, J.}},
location = {{Bamberg, Germany}},
title = {{{Online-Bestimmung der Sauerstofftransferrate (OTR) und der Kohlendioxidtransferrate (CTR) in geschüttelten Bioreaktoren}}},
year = {{2000}},
}
@misc{2959,
author = {{Hoffmann, M. and Frahm, Björn and Schwabe, J.-O. and Lane, P. and Pörtner, R. and Hass, V. C. and Munack, A.}},
location = {{Heilbad Heiligenstadt, Germany}},
title = {{{Modellgestützte Prozessführung für Hybridoma-Kulturen mit Hilfe des Open-Loop-Feedback-Optimal (OLFO)- Algorithmus}}},
year = {{2000}},
}
@article{3352,
author = {{Müller, Ulrich and Dohmann, Joachim}},
journal = {{Lebensmitteltechnik}},
number = {{10}},
title = {{{Optimale Temperaturen fahren - Entwicklungen in der Kältetechnik}}},
volume = {{32}},
year = {{2000}},
}