---
_id: '5504'
author:
- first_name: Linda
full_name: Katsch, Linda
id: '71614'
last_name: Katsch
orcid: '0000-0001-6628-3929 '
- first_name: Jan
full_name: Schneider, Jan
id: '13209'
last_name: Schneider
orcid: 0000-0001-6401-8873
citation:
ama: Katsch L, Schneider J. Potential für eine schonendere Pasteurisation. Brauwelt.
2021;(14):340-343.
apa: Katsch, L., & Schneider, J. (2021). Potential für eine schonendere Pasteurisation.
Brauwelt, 14, 340–343.
bjps: Katsch L and Schneider J (2021) Potential Für Eine Schonendere Pasteurisation.
Brauwelt 340–343.
chicago: 'Katsch, Linda, and Jan Schneider. “Potential Für Eine Schonendere Pasteurisation.”
Brauwelt, no. 14 (2021): 340–43.'
chicago-de: 'Katsch, Linda und Jan Schneider. 2021. Potential für eine schonendere
Pasteurisation. Brauwelt, Nr. 14: 340–343.'
din1505-2-1: 'Katsch, Linda ; Schneider, Jan: Potential für eine schonendere
Pasteurisation. In: Brauwelt. Nürnberg, Fachverlag Hans Carl GmbH (2021),
Nr. 14, S. 340–343'
havard: L. Katsch, J. Schneider, Potential für eine schonendere Pasteurisation,
Brauwelt. (2021) 340–343.
ieee: L. Katsch and J. Schneider, “Potential für eine schonendere Pasteurisation,”
Brauwelt, no. 14, pp. 340–343, 2021.
mla: Katsch, Linda, and Jan Schneider. “Potential Für Eine Schonendere Pasteurisation.”
Brauwelt, no. 14, 2021, pp. 340–43.
short: L. Katsch, J. Schneider, Brauwelt (2021) 340–343.
ufg: 'Katsch, Linda/Schneider, Jan: Potential für eine schonendere Pasteurisation,
in: Brauwelt (2021), H. 14, S. 340–343.'
van: Katsch L, Schneider J. Potential für eine schonendere Pasteurisation. Brauwelt.
2021;(14):340–3.
date_created: 2021-04-13T12:03:12Z
date_updated: 2025-02-10T07:07:05Z
department:
- _id: DEP4018
- _id: DEP1308
- _id: DEP4028
issue: '14'
language:
- iso: eng
main_file_link:
- url: https://www.wiso-net.de/toc_list/BW/2021/BW__%3A2021%3A14/Heft%2B14%2B%252F%2B2021/BW#
page: 340-343
place: Nürnberg
publication: Brauwelt
publication_identifier:
eissn:
- 1439-5177
issn:
- 0724-696X
publication_status: published
publisher: Fachverlag Hans Carl GmbH
status: public
title: Potential für eine schonendere Pasteurisation
type: industry_journal_article
user_id: '83781'
year: '2021'
...
---
_id: '12805'
abstract:
- lang: eng
text: 'n recent decades, the demand for palm oil has constantly increased and with
it the cultivation of oil palms. After a period of 25 years, the oil yield of
the palm trees decreases and they are felled. The trees are cut into pieces and
remain on the plantations. However, due to their high moisture and sugar content,
fungi and molds cause problems for replanting. The use of the wood for the timber
industry is difficult due to its structural characteristics. Biotechnological
processes use microorganisms to produce relevant industrial products. The basis
for each process is a culture medium that contains all necessary nutrients, especially
carbohydrates. The culture medium makes up a high percentage of the costs, so
alternative, cheaper substrates are preferred. In this review, we show and compare
different analyses of the sap mechanically pressed from the oil palm trunk regarding
its sugar and nutrient content. The total sugar concentration in the palm sap
varies between 16.97–140 g L−1 and it is mainly composed
of glucose, fructose, and sucrose. The comparison with common nutrient media and
the results of fermentation processes already carried out on a laboratory scale
show that palm sap offers great potential as a fermentation medium for biotechnological
conversion into industrially relevant products. '
author:
- first_name: Rabea
full_name: Dirkes, Rabea
id: '68594'
last_name: Dirkes
- first_name: Pia Rebecca
full_name: Neubauer, Pia Rebecca
id: '75420'
last_name: Neubauer
- first_name: Jürgen
full_name: Rabenhorst, Jürgen
id: '13454'
last_name: Rabenhorst
citation:
ama: 'Dirkes R, Neubauer PR, Rabenhorst J. Pressed sap from oil palm (<scp>Elaeis
guineensis</scp>) trunks: a revolutionary growth medium for the biotechnological
industry? Biofuels, Bioproducts and Biorefining. 2021;15(3):931-944. doi:10.1002/bbb.2201'
apa: 'Dirkes, R., Neubauer, P. R., & Rabenhorst, J. (2021). Pressed sap from
oil palm (<scp>Elaeis guineensis</scp>) trunks: a revolutionary
growth medium for the biotechnological industry? Biofuels, Bioproducts and
Biorefining, 15(3), 931–944. https://doi.org/10.1002/bbb.2201'
bjps: 'Dirkes R, Neubauer PR and Rabenhorst J (2021) Pressed Sap from Oil
Palm (<scp>Elaeis Guineensis</Scp>) Trunks: A Revolutionary
Growth Medium for the Biotechnological Industry? Biofuels, Bioproducts and
Biorefining 15, 931–944.'
chicago: 'Dirkes, Rabea, Pia Rebecca Neubauer, and Jürgen Rabenhorst. “Pressed Sap
from Oil Palm (<scp>Elaeis Guineensis</Scp>) Trunks: A
Revolutionary Growth Medium for the Biotechnological Industry?” Biofuels, Bioproducts
and Biorefining 15, no. 3 (2021): 931–44. https://doi.org/10.1002/bbb.2201.'
chicago-de: 'Dirkes, Rabea, Pia Rebecca Neubauer und Jürgen Rabenhorst. 2021. Pressed
sap from oil palm (<scp>Elaeis guineensis</scp>) trunks:
a revolutionary growth medium for the biotechnological industry? Biofuels,
Bioproducts and Biorefining 15, Nr. 3: 931–944. doi:10.1002/bbb.2201,
.'
din1505-2-1: 'Dirkes, Rabea ; Neubauer, Pia Rebecca ; Rabenhorst,
Jürgen: Pressed sap from oil palm (<scp>Elaeis guineensis</scp>)
trunks: a revolutionary growth medium for the biotechnological industry? In: Biofuels,
Bioproducts and Biorefining Bd. 15. Chichester, Wiley (2021), Nr. 3, S. 931–944'
havard: 'R. Dirkes, P.R. Neubauer, J. Rabenhorst, Pressed sap from oil palm (<scp>Elaeis
guineensis</scp>) trunks: a revolutionary growth medium for the biotechnological
industry?, Biofuels, Bioproducts and Biorefining. 15 (2021) 931–944.'
ieee: 'R. Dirkes, P. R. Neubauer, and J. Rabenhorst, “Pressed sap from oil palm
(<scp>Elaeis guineensis</scp>) trunks: a revolutionary
growth medium for the biotechnological industry?,” Biofuels, Bioproducts and
Biorefining, vol. 15, no. 3, pp. 931–944, 2021, doi: 10.1002/bbb.2201.'
mla: 'Dirkes, Rabea, et al. “Pressed Sap from Oil Palm (<scp>Elaeis Guineensis</Scp>)
Trunks: A Revolutionary Growth Medium for the Biotechnological Industry?” Biofuels,
Bioproducts and Biorefining, vol. 15, no. 3, 2021, pp. 931–44, https://doi.org/10.1002/bbb.2201.'
short: R. Dirkes, P.R. Neubauer, J. Rabenhorst, Biofuels, Bioproducts and Biorefining
15 (2021) 931–944.
ufg: 'Dirkes, Rabea/Neubauer, Pia Rebecca/Rabenhorst, Jürgen: Pressed sap
from oil palm (<scp>Elaeis guineensis</scp>) trunks: a
revolutionary growth medium for the biotechnological industry?, in: Biofuels,
Bioproducts and Biorefining 15 (2021), H. 3, S. 931–944.'
van: 'Dirkes R, Neubauer PR, Rabenhorst J. Pressed sap from oil palm (<scp>Elaeis
guineensis</scp>) trunks: a revolutionary growth medium for the biotechnological
industry? Biofuels, Bioproducts and Biorefining. 2021;15(3):931–44.'
date_created: 2025-04-16T07:00:19Z
date_updated: 2025-06-26T13:37:39Z
department:
- _id: DEP4000
- _id: DEP4028
- _id: DEP4018
doi: 10.1002/bbb.2201
external_id:
isi:
- '000625400200001'
intvolume: ' 15'
isi: '1'
issue: '3'
keyword:
- oil palm
- trunks
- pressed sap
- Elaeis guineensis
- sugar
- nutrients
- review
language:
- iso: eng
page: 931-944
place: Chichester
publication: Biofuels, Bioproducts and Biorefining
publication_identifier:
eissn:
- 1932-1031
issn:
- 1932-104X
publication_status: published
publisher: Wiley
status: public
title: 'Pressed sap from oil palm (Elaeis guineensis) trunks: a
revolutionary growth medium for the biotechnological industry?'
type: scientific_journal_article
user_id: '83781'
volume: 15
year: '2021'
...
---
_id: '12835'
abstract:
- lang: eng
text: Delayed-release dosage forms are mainly manufactured as batch processes and
include coated tablets, pellets, or particles with gastric resistant polymers.
Authors propose a novel approach using the hot-melt extrusion technique to prepare
delayed release dosage forms via a continuous manufacturing process, a new trend
in the pharmaceutical industry. A full factorial design was employed to correlate
input variables, including stearic acid (SA) content, drug content, and pellet
size with drug release properties of the pellets. PLS fit method suitably elaborated
the relationship between input and output variables with reasonably good fit and
goodness of prediction. All three input factors influenced drug release in enzyme-free
simulated gastric fluid (SGF) after 120 min; however, SA content did not significantly
affect drug dissolution in the enzyme-free simulated intestinal fluid (SIF). An
optimized formulation and design space were determined by overlaying multiple
contours established from regression equations. The continuous manufacturing process
was successfully monitored using inline near-infrared (NIR) and inline particle
size analysis, with drug load and pellet size being well-controlled within the
design space. The obtained pellets released less than 5% after 120 min in SGF
and more than 85% and 95% after 30 min and 45 min, respectively, after switching
to SIF. (C) 2020 American Pharmacists Association (R). Published by Elsevier Inc.
All rights reserved.
author:
- first_name: Anh Q.
full_name: Vo, Anh Q.
last_name: Vo
- first_name: Gerd
full_name: Kutz, Gerd
id: '12015'
last_name: Kutz
- first_name: Herman
full_name: He, Herman
last_name: He
- first_name: Sagar
full_name: Narala, Sagar
last_name: Narala
- first_name: Suresh
full_name: Bandari, Suresh
last_name: Bandari
- first_name: Michael A.
full_name: Repka, Michael A.
last_name: Repka
citation:
ama: 'Vo AQ, Kutz G, He H, Narala S, Bandari S, Repka MA. Continuous Manufacturing
of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application
of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. Journal
of Pharmaceutical Sciences. 2020;109(12):3598-3607. doi:10.1016/j.xphs.2020.09.007'
apa: 'Vo, A. Q., Kutz, G., He, H., Narala, S., Bandari, S., & Repka, M. A. (2020).
Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion
Technology: Application of QbD Design Space, Inline Near Infrared, and Inline
Pellet Size Analysis. Journal of Pharmaceutical Sciences, 109(12),
3598–3607. https://doi.org/10.1016/j.xphs.2020.09.007'
bjps: 'Vo AQ et al. (2020) Continuous Manufacturing of Ketoprofen
Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design
Space, Inline Near Infrared, and Inline Pellet Size Analysis. Journal of Pharmaceutical
Sciences 109, 3598–3607.'
chicago: 'Vo, Anh Q., Gerd Kutz, Herman He, Sagar Narala, Suresh Bandari, and Michael
A. Repka. “Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using
Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared,
and Inline Pellet Size Analysis.” Journal of Pharmaceutical Sciences 109,
no. 12 (2020): 3598–3607. https://doi.org/10.1016/j.xphs.2020.09.007.'
chicago-de: 'Vo, Anh Q., Gerd Kutz, Herman He, Sagar Narala, Suresh Bandari und
Michael A. Repka. 2020. Continuous Manufacturing of Ketoprofen Delayed Release
Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline
Near Infrared, and Inline Pellet Size Analysis. Journal of Pharmaceutical Sciences
109, Nr. 12: 3598–3607. doi:10.1016/j.xphs.2020.09.007,
.'
din1505-2-1: 'Vo, Anh Q. ; Kutz,
Gerd ; He, Herman ; Narala, Sagar ; Bandari,
Suresh ; Repka, Michael A.:
Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion
Technology: Application of QbD Design Space, Inline Near Infrared, and Inline
Pellet Size Analysis. In: Journal of Pharmaceutical Sciences Bd. 109. Amsterdam
[u.a.], Elsevier BV (2020), Nr. 12, S. 3598–3607'
havard: 'A.Q. Vo, G. Kutz, H. He, S. Narala, S. Bandari, M.A. Repka, Continuous
Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology:
Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size
Analysis, Journal of Pharmaceutical Sciences. 109 (2020) 3598–3607.'
ieee: 'A. Q. Vo, G. Kutz, H. He, S. Narala, S. Bandari, and M. A. Repka, “Continuous
Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology:
Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size
Analysis,” Journal of Pharmaceutical Sciences, vol. 109, no. 12, pp. 3598–3607,
2020, doi: 10.1016/j.xphs.2020.09.007.'
mla: 'Vo, Anh Q., et al. “Continuous Manufacturing of Ketoprofen Delayed Release
Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline
Near Infrared, and Inline Pellet Size Analysis.” Journal of Pharmaceutical
Sciences, vol. 109, no. 12, 2020, pp. 3598–607, https://doi.org/10.1016/j.xphs.2020.09.007.'
short: A.Q. Vo, G. Kutz, H. He, S. Narala, S. Bandari, M.A. Repka, Journal of Pharmaceutical
Sciences 109 (2020) 3598–3607.
ufg: 'Vo, Anh Q. u. a.: Continuous Manufacturing of Ketoprofen Delayed Release
Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline
Near Infrared, and Inline Pellet Size Analysis, in: Journal of Pharmaceutical
Sciences 109 (2020), H. 12, S. 3598–3607.'
van: 'Vo AQ, Kutz G, He H, Narala S, Bandari S, Repka MA. Continuous Manufacturing
of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application
of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. Journal
of Pharmaceutical Sciences. 2020;109(12):3598–607.'
date_created: 2025-04-23T08:40:12Z
date_updated: 2025-06-26T13:25:32Z
department:
- _id: DEP4028
doi: 10.1016/j.xphs.2020.09.007
external_id:
isi:
- '000590406100010'
intvolume: ' 109'
isi: '1'
issue: '12'
keyword:
- Continuous manufacturing
- Delayed-release
- FT-NIR
- Inline particle size analysis
- Hot melt extrusion
language:
- iso: eng
page: 3598-3607
place: Amsterdam [u.a.]
publication: Journal of Pharmaceutical Sciences
publication_identifier:
eissn:
- 1520-6017
issn:
- 0022-3549
publication_status: published
publisher: Elsevier BV
status: public
title: 'Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt
Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and
Inline Pellet Size Analysis'
type: scientific_journal_article
user_id: '83781'
volume: 109
year: '2020'
...