---
_id: '12402'
abstract:
- lang: eng
text: In anaerobic technology, pH values are crucial for targeted volatile fatty
acid production. While pH dynamics can be modeled using the Anaerobic Digestion
Model No. 1 (ADM1), simulation results may be biased. To address this issue, the
pH prediction routine of Visual Water, a specialized water chemistry simulator,
was validated. Unlike ADM1, it accounts for ionic strength and activities while
also providing an automated uncertainty analysis. The analysis revealed Visual Water
simulations to better fit measured pH data from acidic solutions in a miniaturized
stirred-tank reactor.
author:
- first_name: Pascal
full_name: Kosse, Pascal
last_name: Kosse
- first_name: Tanja
full_name: Hernández Rodriguez, Tanja
id: '52466'
last_name: Hernández Rodriguez
- first_name: Björn
full_name: Frahm, Björn
id: '45666'
last_name: Frahm
- first_name: Manfred
full_name: Lübken, Manfred
last_name: Lübken
- first_name: Marc
full_name: Wichern, Marc
last_name: Wichern
citation:
ama: Kosse P, Hernández Rodriguez T, Frahm B, Lübken M, Wichern M. Comparative Analysis
of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator.
Chemie Ingenieur Technik. 2024;96(4):528-534. doi:10.1002/cite.202300188
apa: Kosse, P., Hernández Rodriguez, T., Frahm, B., Lübken, M., & Wichern, M.
(2024). Comparative Analysis of pH Prediction Routines in ADM1 and a Specialized
Water Chemistry Simulator. Chemie Ingenieur Technik, 96(4), 528–534.
https://doi.org/10.1002/cite.202300188
bjps: Kosse P et al. (2024) Comparative Analysis of PH Prediction
Routines in ADM1 and a Specialized Water Chemistry Simulator. Chemie Ingenieur
Technik 96, 528–534.
chicago: 'Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken,
and Marc Wichern. “Comparative Analysis of PH Prediction Routines in ADM1 and
a Specialized Water Chemistry Simulator.” Chemie Ingenieur Technik 96,
no. 4 (2024): 528–34. https://doi.org/10.1002/cite.202300188.'
chicago-de: 'Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken
und Marc Wichern. 2024. Comparative Analysis of pH Prediction Routines in ADM1
and a Specialized Water Chemistry Simulator. Chemie Ingenieur Technik 96,
Nr. 4: 528–534. doi:10.1002/cite.202300188,
.'
din1505-2-1: 'Kosse, Pascal ; Hernández Rodriguez, Tanja ; Frahm,
Björn ; Lübken, Manfred ;
Wichern, Marc: Comparative Analysis
of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator.
In: Chemie Ingenieur Technik Bd. 96. Weinheim, Wiley (2024), Nr. 4, S. 528–534'
havard: P. Kosse, T. Hernández Rodriguez, B. Frahm, M. Lübken, M. Wichern, Comparative
Analysis of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator,
Chemie Ingenieur Technik. 96 (2024) 528–534.
ieee: 'P. Kosse, T. Hernández Rodriguez, B. Frahm, M. Lübken, and M. Wichern, “Comparative
Analysis of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator,”
Chemie Ingenieur Technik, vol. 96, no. 4, pp. 528–534, 2024, doi: 10.1002/cite.202300188.'
mla: Kosse, Pascal, et al. “Comparative Analysis of PH Prediction Routines in ADM1
and a Specialized Water Chemistry Simulator.” Chemie Ingenieur Technik,
vol. 96, no. 4, 2024, pp. 528–34, https://doi.org/10.1002/cite.202300188.
short: P. Kosse, T. Hernández Rodriguez, B. Frahm, M. Lübken, M. Wichern, Chemie
Ingenieur Technik 96 (2024) 528–534.
ufg: 'Kosse, Pascal u. a.: Comparative Analysis of pH Prediction Routines
in ADM1 and a Specialized Water Chemistry Simulator, in: Chemie Ingenieur Technik
96 (2024), H. 4, S. 528–534.'
van: Kosse P, Hernández Rodriguez T, Frahm B, Lübken M, Wichern M. Comparative Analysis
of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator.
Chemie Ingenieur Technik. 2024;96(4):528–34.
date_created: 2025-01-29T13:49:16Z
date_updated: 2025-06-25T12:42:09Z
department:
- _id: DEP4000
doi: 10.1002/cite.202300188
external_id:
isi:
- '001169606600001'
intvolume: ' 96'
isi: '1'
issue: '4'
keyword:
- Anaerobic Digestion Model No. 1 (ADM1)
- Anaerobic technology
- pH simulation
- Uncertainty assessment
- Visual Water
language:
- iso: eng
page: 528-534
place: Weinheim
publication: Chemie Ingenieur Technik
publication_identifier:
eissn:
- 1522-2640
issn:
- 0009-286X
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Comparative Analysis of pH Prediction Routines in ADM1 and a Specialized Water
Chemistry Simulator
type: scientific_journal_article
user_id: '83781'
volume: 96
year: '2024'
...
---
_id: '12846'
abstract:
- lang: eng
text: "The decarbonization of the energy supply is one of the biggest and most important
challenges of the 21st century. This paper contributes to the solution of the
energy crisis by investigating the stability of alcohols as e-fuels. The focus
is on the investigation of the aging mechanism of the linear alcohols 1-hexanol
and 1-octanol compared to the iso-alcohol 2-hexanol. It is analysed in detail
how the time-dependent aging varies depending on the chain length and the position
of the hydroxy-group, both in the liquid and in the gas phase. It is shown that
a variety of aging products such as aldehydes, acids, short-chain alcohols and
esters are formed during the aging of the n-alcohols by oxidation, decarboxylation,
oxidative C-C bond cleavage and esterification. In contrast, the decomposition
of the iso-alcohol is significantly lower. The results show that the total acid
number is significantly higher for aged n-alcohols than for the aged iso-alcohos,
while the kinematic viscosity decreases for all alcohols during aging. Carbon
mass balancing shows that after accelerated aging for 120 hours, around 80% of
the iso-alcohol is still present, compared to only around 57-63% for the n-alcohols.
In addition, significantly fewer acids are formed with the iso-alcohol. In this
study, iso-alcohols have a higher stability against thermo-oxidative aging compared
to n-alcohols, showing their potential as e-fuels. Furthermore, the chain length
of the alcohols has also an influence on aging, as more different aging products
can be formed with increasing chain length.\r\n\r\nThis paper contributes to the
solution of the energy crisis by investigating the stability of alcohols as e-fuels.
The focus is on the investigation of the aging mechanism of 1-hexanol and 1-octanol
compared to the 2-hexanol."
author:
- first_name: Anne
full_name: Lichtinger, Anne
last_name: Lichtinger
- first_name: Maximilian J.
full_name: Poller, Maximilian J.
last_name: Poller
- first_name: Olaf
full_name: Schröder, Olaf
last_name: Schröder
- first_name: Julian
full_name: Türck, Julian
last_name: Türck
- first_name: Thomas
full_name: Garbe, Thomas
last_name: Garbe
- first_name: Jürgen
full_name: Krahl, Jürgen
id: '68870'
last_name: Krahl
- first_name: Markus
full_name: Jakob, Markus
last_name: Jakob
- first_name: Jakob
full_name: Albert, Jakob
last_name: Albert
citation:
ama: 'Lichtinger A, Poller MJ, Schröder O, et al. Thermo-oxidative aging of linear
and branched alcohols as stability criterion for their use as e-fuels. Sustainable
energy & fuels : interdisciplinary research for the development of sustainable
energy technologies . 2024;8(15):3329-3340. doi:10.1039/d4se00400k'
apa: 'Lichtinger, A., Poller, M. J., Schröder, O., Türck, J., Garbe, T., Krahl,
J., Jakob, M., & Albert, J. (2024). Thermo-oxidative aging of linear and branched
alcohols as stability criterion for their use as e-fuels. Sustainable Energy
& Fuels : Interdisciplinary Research for the Development of Sustainable Energy
Technologies , 8(15), 3329–3340. https://doi.org/10.1039/d4se00400k'
bjps: 'Lichtinger A et al. (2024) Thermo-Oxidative Aging of Linear
and Branched Alcohols as Stability Criterion for Their Use as e-Fuels. Sustainable
energy & fuels : interdisciplinary research for the development of sustainable
energy technologies 8, 3329–3340.'
chicago: 'Lichtinger, Anne, Maximilian J. Poller, Olaf Schröder, Julian Türck, Thomas
Garbe, Jürgen Krahl, Markus Jakob, and Jakob Albert. “Thermo-Oxidative Aging of
Linear and Branched Alcohols as Stability Criterion for Their Use as e-Fuels.”
Sustainable Energy & Fuels : Interdisciplinary Research for the Development
of Sustainable Energy Technologies 8, no. 15 (2024): 3329–40. https://doi.org/10.1039/d4se00400k.'
chicago-de: 'Lichtinger, Anne, Maximilian J. Poller, Olaf Schröder, Julian Türck,
Thomas Garbe, Jürgen Krahl, Markus Jakob und Jakob Albert. 2024. Thermo-oxidative
aging of linear and branched alcohols as stability criterion for their use as
e-fuels. Sustainable energy & fuels : interdisciplinary research for
the development of sustainable energy technologies 8, Nr. 15: 3329–3340.
doi:10.1039/d4se00400k, .'
din1505-2-1: 'Lichtinger, Anne ; Poller, Maximilian J. ; Schröder,
Olaf ; Türck, Julian ; Garbe, Thomas ; Krahl,
Jürgen ; Jakob, Markus ;
Albert, Jakob: Thermo-oxidative
aging of linear and branched alcohols as stability criterion for their use as
e-fuels. In: Sustainable energy & fuels : interdisciplinary research
for the development of sustainable energy technologies Bd. 8. Cambridge ,
Royal Society of Chemistry (RSC) (2024), Nr. 15, S. 3329–3340'
havard: 'A. Lichtinger, M.J. Poller, O. Schröder, J. Türck, T. Garbe, J. Krahl,
M. Jakob, J. Albert, Thermo-oxidative aging of linear and branched alcohols as
stability criterion for their use as e-fuels, Sustainable Energy & Fuels :
Interdisciplinary Research for the Development of Sustainable Energy Technologies
. 8 (2024) 3329–3340.'
ieee: 'A. Lichtinger et al., “Thermo-oxidative aging of linear and branched
alcohols as stability criterion for their use as e-fuels,” Sustainable energy
& fuels : interdisciplinary research for the development of sustainable energy
technologies , vol. 8, no. 15, pp. 3329–3340, 2024, doi: 10.1039/d4se00400k.'
mla: 'Lichtinger, Anne, et al. “Thermo-Oxidative Aging of Linear and Branched Alcohols
as Stability Criterion for Their Use as e-Fuels.” Sustainable Energy &
Fuels : Interdisciplinary Research for the Development of Sustainable Energy Technologies
, vol. 8, no. 15, 2024, pp. 3329–40, https://doi.org/10.1039/d4se00400k.'
short: 'A. Lichtinger, M.J. Poller, O. Schröder, J. Türck, T. Garbe, J. Krahl, M.
Jakob, J. Albert, Sustainable Energy & Fuels : Interdisciplinary Research
for the Development of Sustainable Energy Technologies 8 (2024) 3329–3340.'
ufg: 'Lichtinger, Anne u. a.: Thermo-oxidative aging of linear and branched
alcohols as stability criterion for their use as e-fuels, in: Sustainable
energy & fuels : interdisciplinary research for the development of sustainable
energy technologies 8 (2024), H. 15, S. 3329–3340.'
van: 'Lichtinger A, Poller MJ, Schröder O, Türck J, Garbe T, Krahl J, et al. Thermo-oxidative
aging of linear and branched alcohols as stability criterion for their use as
e-fuels. Sustainable energy & fuels : interdisciplinary research for the
development of sustainable energy technologies . 2024;8(15):3329–40.'
date_created: 2025-04-23T12:27:18Z
date_updated: 2025-06-25T13:00:39Z
department:
- _id: DEP1408
doi: 10.1039/d4se00400k
external_id:
isi:
- '001253422700001'
intvolume: ' 8'
isi: '1'
issue: '15'
keyword:
- OXIDATION
- 1-OCTANOL
- PERFORMANCE
- CATALYSTS
- KINETICS
- ACID
language:
- iso: eng
page: 3329-3340
place: 'Cambridge '
publication: ' Sustainable energy & fuels : interdisciplinary research for the development
of sustainable energy technologies '
publication_identifier:
issn:
- 2398-4902
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Thermo-oxidative aging of linear and branched alcohols as stability criterion
for their use as e-fuels
type: scientific_journal_article
user_id: '83781'
volume: 8
year: '2024'
...
---
_id: '12984'
abstract:
- lang: eng
text: "Background\r\nPseudoxanthoma elasticum (PXE) is a rare hereditary disorder
characterized by late onset and progressive calcification of elastic fibers in
skin, eyes and the cardiovascular system, exemplifying a model for conditions
characterized by soft tissue calcification.\r\nObjective\r\nThe aim of our study
was to characterize cellular inorganic pyrophosphate (PPi) homeostasis in PXE.\r\nMethods\r\nGene
expression of PPi metabolizing enzymes was determined by quantitative real-time
PCR after incubation up to 21 days with or without addition of Na2HPO4. Extracellular
and cytosolic PPi concentrations were measured by enzyme-linked bioluminescence
assay. ALP and ENPP1 activity was determined spectrophotometrically. We further
established a human cell culture model suitable for investigating PXE and related
disorders without addition of artificial calcification triggers.\r\nResults\r\nIndependently
of the experimental conditions, PXE fibroblasts revealed a higher degree of matrix
calcification. We observed that matrix calcification was associated with altered
gene expression of PPi metabolizing enzymes in PXE fibroblasts. In this context,
PXE fibroblasts exhibited significantly higher expression of ALP and OPN and reduced
mRNA expression and activity of ENPP1. Here, for the first time cytosolic and
extracellular PPi levels were shown to be strongly reduced in PXE fibroblasts.
We further showed that PPi concentration in bovine and human sera additives had
a strong impact on matrix calcification. In a last experimental line, we demonstrated
that addition of PPi analogs reduced matrix calcification of PXE fibroblasts most
likely by reducing ALP and OPN mRNA expression, restoring ENPP1 activity and subsequently
elevating PPi concentrations.\r\nConclusion\r\nThe results of our study along
with recent findings point to the essential role of PPi as the central regulatory
metabolites preventing matrix calcification in PXE. But what remains to be determined
is the underlying molecular mechanism leading to depletion of PPi in PXE. We further
suggest that supplementation of PPi analogs might counteract pathological calcification
in PXE and related disorders."
author:
- first_name: Mareike
full_name: Dabisch-Ruthe, Mareike
id: '66516'
last_name: Dabisch-Ruthe
orcid: https://orcid.org/0009-0008-7644-0826
- first_name: Patricia
full_name: Kuzaj, Patricia
last_name: Kuzaj
- first_name: Christian
full_name: Götting, Christian
last_name: Götting
- first_name: Cornelius
full_name: Knabbe, Cornelius
last_name: Knabbe
- first_name: Doris
full_name: Hendig, Doris
last_name: Hendig
citation:
ama: Dabisch-Ruthe M, Kuzaj P, Götting C, Knabbe C, Hendig D. Pyrophosphates as
a major inhibitor of matrix calcification in Pseudoxanthoma elasticum. Journal
of Dermatological Science. 2014;75(2):109-120. doi:10.1016/j.jdermsci.2014.04.015
apa: Dabisch-Ruthe, M., Kuzaj, P., Götting, C., Knabbe, C., & Hendig, D. (2014).
Pyrophosphates as a major inhibitor of matrix calcification in Pseudoxanthoma
elasticum. Journal of Dermatological Science, 75(2), 109–120. https://doi.org/10.1016/j.jdermsci.2014.04.015
bjps: Dabisch-Ruthe M et al. (2014) Pyrophosphates as a Major Inhibitor
of Matrix Calcification in Pseudoxanthoma Elasticum. Journal of Dermatological
Science 75, 109–120.
chicago: 'Dabisch-Ruthe, Mareike, Patricia Kuzaj, Christian Götting, Cornelius Knabbe,
and Doris Hendig. “Pyrophosphates as a Major Inhibitor of Matrix Calcification
in Pseudoxanthoma Elasticum.” Journal of Dermatological Science 75, no.
2 (2014): 109–20. https://doi.org/10.1016/j.jdermsci.2014.04.015.'
chicago-de: 'Dabisch-Ruthe, Mareike, Patricia Kuzaj, Christian Götting, Cornelius
Knabbe und Doris Hendig. 2014. Pyrophosphates as a major inhibitor of matrix calcification
in Pseudoxanthoma elasticum. Journal of Dermatological Science 75, Nr.
2: 109–120. doi:10.1016/j.jdermsci.2014.04.015,
.'
din1505-2-1: 'Dabisch-Ruthe, Mareike
; Kuzaj, Patricia ; Götting,
Christian ; Knabbe, Cornelius
; Hendig, Doris: Pyrophosphates
as a major inhibitor of matrix calcification in Pseudoxanthoma elasticum. In:
Journal of Dermatological Science Bd. 75. Amsterdam, Elsevier (2014),
Nr. 2, S. 109–120'
havard: M. Dabisch-Ruthe, P. Kuzaj, C. Götting, C. Knabbe, D. Hendig, Pyrophosphates
as a major inhibitor of matrix calcification in Pseudoxanthoma elasticum, Journal
of Dermatological Science. 75 (2014) 109–120.
ieee: 'M. Dabisch-Ruthe, P. Kuzaj, C. Götting, C. Knabbe, and D. Hendig, “Pyrophosphates
as a major inhibitor of matrix calcification in Pseudoxanthoma elasticum,” Journal
of Dermatological Science, vol. 75, no. 2, pp. 109–120, 2014, doi: 10.1016/j.jdermsci.2014.04.015.'
mla: Dabisch-Ruthe, Mareike, et al. “Pyrophosphates as a Major Inhibitor of Matrix
Calcification in Pseudoxanthoma Elasticum.” Journal of Dermatological Science,
vol. 75, no. 2, 2014, pp. 109–20, https://doi.org/10.1016/j.jdermsci.2014.04.015.
short: M. Dabisch-Ruthe, P. Kuzaj, C. Götting, C. Knabbe, D. Hendig, Journal of
Dermatological Science 75 (2014) 109–120.
ufg: 'Dabisch-Ruthe, Mareike u. a.: Pyrophosphates as a major inhibitor of
matrix calcification in Pseudoxanthoma elasticum, in: Journal of Dermatological
Science 75 (2014), H. 2, S. 109–120.'
van: Dabisch-Ruthe M, Kuzaj P, Götting C, Knabbe C, Hendig D. Pyrophosphates as
a major inhibitor of matrix calcification in Pseudoxanthoma elasticum. Journal
of Dermatological Science. 2014;75(2):109–20.
date_created: 2025-06-17T06:52:59Z
date_updated: 2025-06-17T13:48:41Z
department:
- _id: DEP4010
doi: 10.1016/j.jdermsci.2014.04.015
intvolume: ' 75'
issue: '2'
keyword:
- Pseudoxanthoma elasticum
- Calcification
- Pyrophosphate
- Bisphosphonate
- ABCC6
- Tissue nonspecific alkaline phosphate
- Ectonucleotide pyrophosphatase 1
language:
- iso: eng
page: 109-120
place: Amsterdam
publication: Journal of Dermatological Science
publication_identifier:
eissn:
- 1873-569X
issn:
- 0923-1811
publication_status: published
publisher: 'Elsevier '
quality_controlled: '1'
status: public
title: Pyrophosphates as a major inhibitor of matrix calcification in Pseudoxanthoma
elasticum
type: scientific_journal_article
user_id: '83781'
volume: 75
year: '2014'
...
---
_id: '12985'
abstract:
- lang: eng
text: "Objectives\r\nPseudoxanthoma elasticum (PXE) is a rare hereditary disorder
characterized by progressive calcification and fragmentation of elastic fibers.
Because of the great clinical variability between PXE patients the involvement
of modifier genes was recently suggested. Therefore, we investigated the association
of single nucleotide variants (SNVs) in selected candidate genes known to regulate
cellular pyrophosphate metabolism.\r\nDesign and methods\r\nWe used RLFP analyses
to evaluate the distribution of SNVs in alkaline phosphatase (ALP), ectonucleotide
pyrophosphatase 1 (ENPP1) and ankylosis (ANKH) in DNA samples from 190 German
PXE patients and 190 age- and sex-matched healthy controls. Statistical analyses
were performed using Fisher exact test and Bonferroni correction.\r\nResults\r\nThe
screening revealed three different SNVs in three genes, which were associated
with PXE. The SNV c.1190-65C > A (rs1780329, minor allele frequency (MAF) patients:
0.17; controls: 0.11; P = 0.04) in the ALP gene was significantly more frequent
in PXE patients. Furthermore, PXE was highly associated with ANKH p.A98A genotype
TT (P = 0.0012), although the MAF was not different between patients and controls.
After correction for multiple testing according to the Bonferroni method, one
SNV in the ENPP1 gene (c.313 + 9G > T, rs7773477) remained significantly associated
with PXE with significantly higher MAF values in the patient cohort (MAF: 0.04
vs. 0.00; P = 0.0024) and a high association with PXE susceptibility (OR 27.96).\r\nConclusion\r\nPolymorphisms
in ALP, ENPP1 and ANKH are important genetic risk factors contributing to PXE."
author:
- first_name: Mareike
full_name: Dabisch-Ruthe, Mareike
id: '66516'
last_name: Dabisch-Ruthe
orcid: https://orcid.org/0009-0008-7644-0826
- first_name: Alexander
full_name: Brock, Alexander
last_name: Brock
- first_name: Patricia
full_name: Kuzaj, Patricia
last_name: Kuzaj
- first_name: Peter
full_name: Charbel Issa, Peter
last_name: Charbel Issa
- first_name: Christiane
full_name: Szliska, Christiane
last_name: Szliska
- first_name: Cornelius
full_name: Knabbe, Cornelius
last_name: Knabbe
- first_name: Doris
full_name: Hendig, Doris
last_name: Hendig
citation:
ama: Dabisch-Ruthe M, Brock A, Kuzaj P, et al. Variants in genes encoding pyrophosphate
metabolizing enzymes are associated with Pseudoxanthoma elasticum. Clinical
Biochemistry. 2014;47(15):60-67. doi:10.1016/j.clinbiochem.2014.07.003
apa: Dabisch-Ruthe, M., Brock, A., Kuzaj, P., Charbel Issa, P., Szliska, C., Knabbe,
C., & Hendig, D. (2014). Variants in genes encoding pyrophosphate metabolizing
enzymes are associated with Pseudoxanthoma elasticum. Clinical Biochemistry,
47(15), 60–67. https://doi.org/10.1016/j.clinbiochem.2014.07.003
bjps: Dabisch-Ruthe M et al. (2014) Variants in Genes Encoding Pyrophosphate
Metabolizing Enzymes Are Associated with Pseudoxanthoma Elasticum. Clinical
Biochemistry 47, 60–67.
chicago: 'Dabisch-Ruthe, Mareike, Alexander Brock, Patricia Kuzaj, Peter Charbel
Issa, Christiane Szliska, Cornelius Knabbe, and Doris Hendig. “Variants in Genes
Encoding Pyrophosphate Metabolizing Enzymes Are Associated with Pseudoxanthoma
Elasticum.” Clinical Biochemistry 47, no. 15 (2014): 60–67. https://doi.org/10.1016/j.clinbiochem.2014.07.003.'
chicago-de: 'Dabisch-Ruthe, Mareike, Alexander Brock, Patricia Kuzaj, Peter Charbel
Issa, Christiane Szliska, Cornelius Knabbe und Doris Hendig. 2014. Variants in
genes encoding pyrophosphate metabolizing enzymes are associated with Pseudoxanthoma
elasticum. Clinical Biochemistry 47, Nr. 15: 60–67. doi:10.1016/j.clinbiochem.2014.07.003,
.'
din1505-2-1: 'Dabisch-Ruthe, Mareike
; Brock, Alexander ; Kuzaj,
Patricia ; Charbel Issa, Peter
; Szliska, Christiane ; Knabbe,
Cornelius ; Hendig, Doris:
Variants in genes encoding pyrophosphate metabolizing enzymes are associated with
Pseudoxanthoma elasticum. In: Clinical Biochemistry Bd. 47. Amsterdam,
Elsevier (2014), Nr. 15, S. 60–67'
havard: M. Dabisch-Ruthe, A. Brock, P. Kuzaj, P. Charbel Issa, C. Szliska, C. Knabbe,
D. Hendig, Variants in genes encoding pyrophosphate metabolizing enzymes are associated
with Pseudoxanthoma elasticum, Clinical Biochemistry. 47 (2014) 60–67.
ieee: 'M. Dabisch-Ruthe et al., “Variants in genes encoding pyrophosphate
metabolizing enzymes are associated with Pseudoxanthoma elasticum,” Clinical
Biochemistry, vol. 47, no. 15, pp. 60–67, 2014, doi: 10.1016/j.clinbiochem.2014.07.003.'
mla: Dabisch-Ruthe, Mareike, et al. “Variants in Genes Encoding Pyrophosphate Metabolizing
Enzymes Are Associated with Pseudoxanthoma Elasticum.” Clinical Biochemistry,
vol. 47, no. 15, 2014, pp. 60–67, https://doi.org/10.1016/j.clinbiochem.2014.07.003.
short: M. Dabisch-Ruthe, A. Brock, P. Kuzaj, P. Charbel Issa, C. Szliska, C. Knabbe,
D. Hendig, Clinical Biochemistry 47 (2014) 60–67.
ufg: 'Dabisch-Ruthe, Mareike u. a.: Variants in genes encoding pyrophosphate
metabolizing enzymes are associated with Pseudoxanthoma elasticum, in: Clinical
Biochemistry 47 (2014), H. 15, S. 60–67.'
van: Dabisch-Ruthe M, Brock A, Kuzaj P, Charbel Issa P, Szliska C, Knabbe C, et
al. Variants in genes encoding pyrophosphate metabolizing enzymes are associated
with Pseudoxanthoma elasticum. Clinical Biochemistry. 2014;47(15):60–7.
date_created: 2025-06-17T06:53:30Z
date_updated: 2025-06-17T13:48:52Z
department:
- _id: DEP4010
doi: 10.1016/j.clinbiochem.2014.07.003
intvolume: ' 47'
issue: '15'
keyword:
- Pseudoxanthoma elasticum
- Calcification
- Tissue nonspecific alkaline phosphatase
- Ectonucleotide pyrophosphatase 1
- Ankylosis
language:
- iso: eng
page: 60-67
place: Amsterdam
publication: Clinical Biochemistry
publication_identifier:
eissn:
- 1873-2933
issn:
- 0009-9120
publication_status: published
publisher: Elsevier
status: public
title: Variants in genes encoding pyrophosphate metabolizing enzymes are associated
with Pseudoxanthoma elasticum
type: scientific_journal_article
user_id: '83781'
volume: 47
year: '2014'
...