[{"place":"Amsterdam [u.a.] ","doi":"https://doi.org/10.1016/j.procs.2025.01.274","_id":"12719","type":"scientific_journal_article","user_id":"83781","intvolume":"       253","department":[{"_id":"DEP1500"}],"abstract":[{"lang":"eng","text":"A human digital twin (HDT) is a virtual representation of a worker in cyberspace. Nevertheless, current research focusses mainly on HDTs for motoric work types, such as assembly. To fully integrate an HDT for workers in production, it is necessary that an HDT also displays cognitive processes like memorizing, thinking or reasoning. Such a concept can be used in information-based work, for example monitoring highly automated production systems, and contribute to the planning and control of production. Due to the high proportion of planning and decision-making processes, the efficiency of information-based work is determined in particular by the inner processes of the worker. An HDT can therefore help to describe current and future states of socio-technical work systems. Therefore, this paper presents a systematic literature review to explicitly derive the relevant components of an HDT for information-based work types. The elements of such an HDT and its environment are defined. Further, the current gaps in literature are identified. There are currently no real-world applications of such an HDT. Additionally, the value of multi-HDT systems must be evaluated more extensively."}],"quality_controlled":"1","publisher":"Elsevier","publication_status":"published","oa":"1","language":[{"iso":"eng"}],"keyword":["Human-centric Production","Digital Twin","Systematic Literature Review"],"date_created":"2025-03-19T15:42:16Z","publication":"Procedia Computer Science","publication_identifier":{"issn":["1877-0509"]},"date_updated":"2025-03-20T15:25:28Z","related_material":{"link":[{"relation":"other","url":"10.1016/j.procs.2025.01.274"}]},"year":"2025","author":[{"last_name":"Mordaschew","full_name":"Mordaschew, Viktoria","id":"79005","first_name":"Viktoria"},{"full_name":"Latos, Benedikt","first_name":"Benedikt","last_name":"Latos","id":"84474"},{"first_name":"Sven","id":"71470","full_name":"Tackenberg, Sven","last_name":"Tackenberg"}],"main_file_link":[{"open_access":"1","url":"https://pdf.sciencedirectassets.com/280203/1-s2.0-S1877050925X0003X/1-s2.0-S1877050925002820/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjECAaCXVzLWVhc3QtMSJHMEUCIQCf5kQu9Qr%2FPaWZOMmUyMsrFj8U0OTeGci9WwFRKvOC4gIgBa8ilRkd264I5%2FfOe%2FJMwvNc3cQ1jDt8wJcUIdPTdfEqswUIeBAFGgwwNTkwMDM1NDY4NjUiDKfD4vTsP8l575BscSqQBdaN09lRB973%2Bhd4ufVIhFw27Ohx%2FUPVSwOUefsN5C28R6CqOhF8DiP%2F2uLmz%2FP0AnXXRIOIU9Xo6jGS01m5JEQUa3nNGi8YJ8wTH4vqk0pOjczyIo6CZJWe2zwVPJVIvlfTEV1aBcggnpVmcBINCHhCQ20GVehLrEEaONMkGjoauiuvp%2B5GQRNaa0F%2FJuhCfsJO7KbRcA1OblcOezoMYk83RzISbfAI5FvDKWxZQhWCprKR35b%2F6s7lfY8fb34Ps%2BNsCYmKhTJlDLDQiFVQPPWUwJg9PJaW9CJxjvWWNXlOOpv0tC6JFHyGnTu6VyOsPqs8G%2BD0nTOJtE9C2AwrradO7sVKQu%2B3SubbOofB6RIbb7eP%2FJeCAN3UQ4wBJKDa2QzoZiqrGb1LUVPmuJgEDZmZNgdIiat3mvC3QsCowARjBq%2BX12qexIsGbLoKKwLj0XZyD1geFAULOxEO1prmNT8zdhXcCloLKivRqNRpHc9vXR8mnUPRY4SDQIiFjkwbGfiN7XIfU%2BUL31K5F4L%2FidNQcNNwxiW2JiZLKnd0Cd3YUYFLODxKrXvI3SboFa1aKhiwX4uba2qjCbu0VpSKGIn%2BdkaGfOWxGgEg2L6s6MWXs0%2BnIUYoYswyjYxyksWZTk2xk09FT%2FzZzcbV%2By3LDfI68M6Yl%2BI47d77Gw2Dl3i2QtpSSgE7KidmuP3V5QTNLcwQ6znfvdJ1GCEtg86RCRbhdIjqopU8zl6%2BH%2By%2B9Zsh8exwsS6wehDEsKBgtOsmXMRr3PIMVsVBZBvOsraGPdmR9%2BFF37YCd66MEc2RLxoWr0y2N7vz00YOlcSvpDR4MLZVSb9sFSBLDTcbdljUEJjFWI5lx4fXoYY6D43k1qzBMKG8674GOrEBPhb%2BOxSm119COf1hZVU9Ddv020oO9bIFU0RN%2BgW0Jn5aIEYvqvKyOjBIlgPe%2BsOxmje4KstmmeZdXNT1UYhFmal1oQ%2Fc6dU2N5e6BPyHNN1HFQEDPCg4VmTPqvA6AerHmcIv62dF2mbJmBlB%2FrchNqLbPCrVy61C9FIKZmBRAdEDMKOjdi0IwDgJ4Mci%2FTu%2FYKZthYyoTcZCmkmyk8hVJGTMyZsj0pGsTS79eyd00t6K&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20250319T153721Z&X-Amz-SignedHeaders=host&X-Amz-Expires=300&X-Amz-Credential=ASIAQ3PHCVTY5KE6SOXB%2F20250319%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Signature=8a9c4609a533337efabc8cf0808d3c276fbf5283eef7c3deb5ab723e49e72788&hash=1c87cbc6d5873de51b1b1ba6cab66fb8a783c2b9af8ef198f4c9b2504f659005&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S1877050925002820&tid=spdf-72598068-bcf7-4dec-b3a9-3bde6d19d9f5&sid=c9f5630d128d5441213b35f764412ad9bb5bgxrqb&type=client&tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&rh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&ua=1e0359535c0b5400015202&rr=922e0cf0ff4e7a5a&cc=de"}],"page":"2137-2146","status":"public","title":"A Human Digital Twin for Worker-Centric Production","citation":{"ufg":"<b>Mordaschew, Viktoria/Latos, Benedikt/Tackenberg, Sven</b>: A Human Digital Twin for Worker-Centric Production, in: <i>Procedia Computer Science</i> 253 (2025),  S. 2137–2146.","mla":"Mordaschew, Viktoria, et al. “A Human Digital Twin for Worker-Centric Production.” <i>Procedia Computer Science</i>, vol. 253, 2025, pp. 2137–46, <a href=\"https://doi.org/10.1016/j.procs.2025.01.274\">https://doi.org/10.1016/j.procs.2025.01.274</a>.","bjps":"<b>Mordaschew V, Latos B and Tackenberg S</b> (2025) A Human Digital Twin for Worker-Centric Production. <i>Procedia Computer Science</i> <b>253</b>, 2137–2146.","havard":"V. Mordaschew, B. Latos, S. Tackenberg, A Human Digital Twin for Worker-Centric Production, Procedia Computer Science. 253 (2025) 2137–2146.","van":"Mordaschew V, Latos B, Tackenberg S. A Human Digital Twin for Worker-Centric Production. Procedia Computer Science. 2025;253:2137–46.","chicago":"Mordaschew, Viktoria, Benedikt Latos, and Sven Tackenberg. “A Human Digital Twin for Worker-Centric Production.” <i>Procedia Computer Science</i> 253 (2025): 2137–46. <a href=\"https://doi.org/10.1016/j.procs.2025.01.274\">https://doi.org/10.1016/j.procs.2025.01.274</a>.","apa":"Mordaschew, V., Latos, B., &#38; Tackenberg, S. (2025). A Human Digital Twin for Worker-Centric Production. <i>Procedia Computer Science</i>, <i>253</i>, 2137–2146. <a href=\"https://doi.org/10.1016/j.procs.2025.01.274\">https://doi.org/10.1016/j.procs.2025.01.274</a>","chicago-de":"Mordaschew, Viktoria, Benedikt Latos und Sven Tackenberg. 2025. A Human Digital Twin for Worker-Centric Production. <i>Procedia Computer Science</i> 253: 2137–2146. doi:<a href=\"https://doi.org/10.1016/j.procs.2025.01.274\">https://doi.org/10.1016/j.procs.2025.01.274</a>, .","din1505-2-1":"<span style=\"font-variant:small-caps;\">Mordaschew, Viktoria</span> ; <span style=\"font-variant:small-caps;\">Latos, Benedikt</span> ; <span style=\"font-variant:small-caps;\">Tackenberg, Sven</span>: A Human Digital Twin for Worker-Centric Production. In: <i>Procedia Computer Science</i> Bd. 253. Amsterdam [u.a.] , Elsevier (2025), S. 2137–2146","short":"V. Mordaschew, B. Latos, S. Tackenberg, Procedia Computer Science 253 (2025) 2137–2146.","ama":"Mordaschew V, Latos B, Tackenberg S. A Human Digital Twin for Worker-Centric Production. <i>Procedia Computer Science</i>. 2025;253:2137-2146. doi:<a href=\"https://doi.org/10.1016/j.procs.2025.01.274\">https://doi.org/10.1016/j.procs.2025.01.274</a>","ieee":"V. Mordaschew, B. Latos, and S. Tackenberg, “A Human Digital Twin for Worker-Centric Production,” <i>Procedia Computer Science</i>, vol. 253, pp. 2137–2146, 2025, doi: <a href=\"https://doi.org/10.1016/j.procs.2025.01.274\">https://doi.org/10.1016/j.procs.2025.01.274</a>."},"volume":253},{"language":[{"iso":"eng"}],"keyword":["Human Digital Twin","Industry 4.0","Sheltered Workshops","Production Planning"],"date_created":"2025-04-15T12:07:15Z","publication":"5th International Conference on Industry 4.0 and Smart Manufacturing (ISM)","publication_identifier":{"issn":["1877-0509"]},"date_updated":"2025-06-25T12:44:44Z","editor":[{"full_name":"Longo, F.","last_name":"Longo","first_name":"F."},{"first_name":"W.","full_name":"Shen, W.","last_name":"Shen"},{"first_name":"A.","last_name":"Padovano","full_name":"Padovano, A."}],"author":[{"first_name":"Viktoria","id":"79005","full_name":"Mordaschew, Viktoria","last_name":"Mordaschew"},{"id":"81325","full_name":"Duckwitz, Sönke","first_name":"Sönke","last_name":"Duckwitz"},{"id":"71470","first_name":"Sven","last_name":"Tackenberg","full_name":"Tackenberg, Sven"}],"year":"2024","page":"745-751","status":"public","title":"A Human Digital Twin of Disabled Workers for Production Planning","volume":232,"citation":{"chicago":"Mordaschew, Viktoria, Sönke Duckwitz, and Sven Tackenberg. <i>A Human Digital Twin of Disabled Workers for Production Planning</i>. Edited by F. Longo, W. Shen, and A. Padovano. <i>5th International Conference on Industry 4.0 and Smart Manufacturing (ISM)</i>. Vol. 232. Procedia Computer Science. Amsterdam [u.a.]: Elsevier BV, 2024. <a href=\"https://doi.org/10.1016/j.procs.2024.01.074\">https://doi.org/10.1016/j.procs.2024.01.074</a>.","apa":"Mordaschew, V., Duckwitz, S., &#38; Tackenberg, S. (2024). A Human Digital Twin of Disabled Workers for Production Planning. In F. Longo, W. Shen, &#38; A. Padovano (Eds.), <i>5th International Conference on Industry 4.0 and Smart Manufacturing (ISM)</i> (Vol. 232, pp. 745–751). Elsevier BV. <a href=\"https://doi.org/10.1016/j.procs.2024.01.074\">https://doi.org/10.1016/j.procs.2024.01.074</a>","ieee":"V. Mordaschew, S. Duckwitz, and S. Tackenberg, <i>A Human Digital Twin of Disabled Workers for Production Planning</i>, vol. 232. Amsterdam [u.a.]: Elsevier BV, 2024, pp. 745–751. doi: <a href=\"https://doi.org/10.1016/j.procs.2024.01.074\">10.1016/j.procs.2024.01.074</a>.","ufg":"<b>Mordaschew, Viktoria/Duckwitz, Sönke/Tackenberg, Sven</b>: A Human Digital Twin of Disabled Workers for Production Planning, Bd. 232, hg. von Longo, F./Shen, W./Padovano, A., Amsterdam [u.a.] 2024 (Procedia Computer Science).","bjps":"<b>Mordaschew V, Duckwitz S and Tackenberg S</b> (2024) <i>A Human Digital Twin of Disabled Workers for Production Planning</i>, Longo F, Shen W and Padovano A (eds). Amsterdam [u.a.]: Elsevier BV.","havard":"V. Mordaschew, S. Duckwitz, S. Tackenberg, A Human Digital Twin of Disabled Workers for Production Planning, Elsevier BV, Amsterdam [u.a.], 2024.","mla":"Mordaschew, Viktoria, et al. “A Human Digital Twin of Disabled Workers for Production Planning.” <i>5th International Conference on Industry 4.0 and Smart Manufacturing (ISM)</i>, edited by F. Longo et al., vol. 232, Elsevier BV, 2024, pp. 745–51, <a href=\"https://doi.org/10.1016/j.procs.2024.01.074\">https://doi.org/10.1016/j.procs.2024.01.074</a>.","van":"Mordaschew V, Duckwitz S, Tackenberg S. A Human Digital Twin of Disabled Workers for Production Planning. Longo F, Shen W, Padovano A, editors. 5th International Conference on Industry 4.0 and Smart Manufacturing (ISM). Amsterdam [u.a.]: Elsevier BV; 2024. (Procedia Computer Science; vol. 232).","ama":"Mordaschew V, Duckwitz S, Tackenberg S. <i>A Human Digital Twin of Disabled Workers for Production Planning</i>. Vol 232. (Longo F, Shen W, Padovano A, eds.). Elsevier BV; 2024:745-751. doi:<a href=\"https://doi.org/10.1016/j.procs.2024.01.074\">10.1016/j.procs.2024.01.074</a>","chicago-de":"Mordaschew, Viktoria, Sönke Duckwitz und Sven Tackenberg. 2024. <i>A Human Digital Twin of Disabled Workers for Production Planning</i>. Hg. von F. Longo, W. Shen, und A. Padovano. <i>5th International Conference on Industry 4.0 and Smart Manufacturing (ISM)</i>. Bd. 232. Procedia Computer Science. Amsterdam [u.a.]: Elsevier BV. doi:<a href=\"https://doi.org/10.1016/j.procs.2024.01.074\">10.1016/j.procs.2024.01.074</a>, .","din1505-2-1":"<span style=\"font-variant:small-caps;\">Mordaschew, Viktoria</span> ; <span style=\"font-variant:small-caps;\">Duckwitz, Sönke</span> ; <span style=\"font-variant:small-caps;\">Tackenberg, Sven</span> ; <span style=\"font-variant:small-caps;\">Longo, F.</span> ; <span style=\"font-variant:small-caps;\">Shen, W.</span> ; <span style=\"font-variant:small-caps;\">Padovano, A.</span> (Hrsg.): <i>A Human Digital Twin of Disabled Workers for Production Planning</i>, <i>Procedia Computer Science</i>. Bd. 232. Amsterdam [u.a.] : Elsevier BV, 2024","short":"V. Mordaschew, S. Duckwitz, S. Tackenberg, A Human Digital Twin of Disabled Workers for Production Planning, Elsevier BV, Amsterdam [u.a.], 2024."},"place":"Amsterdam [u.a.]","doi":"10.1016/j.procs.2024.01.074","_id":"12795","type":"conference_editor_article","user_id":"83781","intvolume":"       232","conference":{"start_date":"2023-11-22","end_date":"2023-11-24","location":"Lisbon, PORTUGAL","name":"5th International Conference on Industry 4.0 and Smart Manufacturing (ISM)"},"department":[{"_id":"DEP7020"}],"abstract":[{"lang":"eng","text":"Including disabled workers in value-creating work processes is a fundamental and guaranteed human right and is, therefore, an essential goal of society. In Germany, sheltered workshops create the conditions for this inclusion since they are essential to companies' value chains. A central challenge is the inclusion of disabled workers in the value-creation processes, such as in manufacturing or assembly areas. The skills of disabled workers vary since they have individual impairments. Therefore, this paper presents a digital human model, a Human Digital Twin (HDT), for disabled workers. The model maps their skills and supports the production planning and assembly processes. (C) 2024 The Authors. Published by Elsevier B.V."}],"publisher":"Elsevier BV","series_title":"Procedia Computer Science","publication_status":"published"},{"department":[{"_id":"DEP7000"}],"abstract":[{"text":"Background: \r\nErrors can have dangerous consequences, resulting in a preventive strategy in most company-based technical vocational education and training (TVET). On the contrary, errors provide a useful opportunity for learning due to mismatches of mental models and reality and especially to improve occupational safety and health (OSH). \r\nObjective: \r\nThis article presents a didactic concept for developing a learning system based on learning from errors. Learners shall directly experience the consequences of erroneous actions through presenting error consequences in augmented reality to avoid negative, dangerous, or cost-intensive outcomes. \r\nMethods: \r\nEmpirical data prove errors to be particularly effective in TVET. A formal description of a work system is systematically adopted to outline a connection between work, errors concerning OSH, and a didactic concept. A proof-of-concept systematically performs a use case for the developed learning system. It supports critical reflections from a technical, safety, and didactical perspective, naming implications and limitations. \r\nResults: \r\nBy learning from errors, a work-based didactic concept supports OSH competencies relying on a learning system. The latter integrates digital twins of the work system to simulate and visualise dangerous error consequences for identified erroneous actions in a technical proof-of-concept. Results demonstrate the ability to detect action errors in work processes and simulations of error consequences in augmented reality. \r\nConclusion: \r\nThe technical learning system for OSH education extends existing learning approaches by showcasing virtual consequences. However, capabilities are limited regarding prepared learning scenarios with predefined critical errors. Future studies should assess learning effectiveness in an industrial scenario and investigate its usability.","lang":"eng"}],"issue":"4","quality_controlled":"1","publisher":"IOS Press","article_type":"original","publication_status":"published","place":"Amsterdam","doi":"10.3233/WOR-211243","_id":"9360","type":"scientific_journal_article","user_id":"83781","intvolume":"        72","author":[{"last_name":"Goppold","first_name":"Marvin","full_name":"Goppold, Marvin"},{"last_name":"Herrmann","id":"75846","full_name":"Herrmann, Jan-Phillip","first_name":"Jan-Phillip"},{"last_name":"Tackenberg","first_name":"Sven","id":"71470","full_name":"Tackenberg, Sven"},{"first_name":"Christopher","full_name":"Brandl, Christopher","last_name":"Brandl"},{"last_name":"Nitsch ","first_name":"Verena","full_name":"Nitsch , Verena"}],"year":"2022","page":"1563-1575","status":"public","title":"An error-based augmented reality learning system for work-based occupational safety and health education","citation":{"ieee":"M. Goppold, J.-P. Herrmann, S. Tackenberg, C. Brandl, and V. Nitsch , “An error-based augmented reality learning system for work-based occupational safety and health education,” <i>Work</i>, vol. 72, no. 4, pp. 1563–1575, 2022, doi: <a href=\"https://doi.org/10.3233/WOR-211243\">10.3233/WOR-211243</a>.","ama":"Goppold M, Herrmann JP, Tackenberg S, Brandl C, Nitsch  V. An error-based augmented reality learning system for work-based occupational safety and health education. <i>Work</i>. 2022;72(4):1563-1575. doi:<a href=\"https://doi.org/10.3233/WOR-211243\">10.3233/WOR-211243</a>","chicago":"Goppold, Marvin, Jan-Phillip Herrmann, Sven Tackenberg, Christopher Brandl, and Verena Nitsch . “An Error-Based Augmented Reality Learning System for Work-Based Occupational Safety and Health Education.” <i>Work</i> 72, no. 4 (2022): 1563–75. <a href=\"https://doi.org/10.3233/WOR-211243\">https://doi.org/10.3233/WOR-211243</a>.","apa":"Goppold, M., Herrmann, J.-P., Tackenberg, S., Brandl, C., &#38; Nitsch , V. (2022). An error-based augmented reality learning system for work-based occupational safety and health education. <i>Work</i>, <i>72</i>(4), 1563–1575. <a href=\"https://doi.org/10.3233/WOR-211243\">https://doi.org/10.3233/WOR-211243</a>","mla":"Goppold, Marvin, et al. “An Error-Based Augmented Reality Learning System for Work-Based Occupational Safety and Health Education.” <i>Work</i>, vol. 72, no. 4, 2022, pp. 1563–75, <a href=\"https://doi.org/10.3233/WOR-211243\">https://doi.org/10.3233/WOR-211243</a>.","havard":"M. Goppold, J.-P. Herrmann, S. Tackenberg, C. Brandl, V. Nitsch , An error-based augmented reality learning system for work-based occupational safety and health education, Work. 72 (2022) 1563–1575.","bjps":"<b>Goppold M <i>et al.</i></b> (2022) An Error-Based Augmented Reality Learning System for Work-Based Occupational Safety and Health Education. <i>Work</i> <b>72</b>, 1563–1575.","ufg":"<b>Goppold, Marvin u. a.</b>: An error-based augmented reality learning system for work-based occupational safety and health education, in: <i>Work</i> 72 (2022), H. 4,  S. 1563–1575.","van":"Goppold M, Herrmann JP, Tackenberg S, Brandl C, Nitsch  V. An error-based augmented reality learning system for work-based occupational safety and health education. Work. 2022;72(4):1563–75.","chicago-de":"Goppold, Marvin, Jan-Phillip Herrmann, Sven Tackenberg, Christopher Brandl und Verena Nitsch . 2022. An error-based augmented reality learning system for work-based occupational safety and health education. <i>Work</i> 72, Nr. 4: 1563–1575. doi:<a href=\"https://doi.org/10.3233/WOR-211243\">10.3233/WOR-211243</a>, .","din1505-2-1":"<span style=\"font-variant:small-caps;\">Goppold, Marvin</span> ; <span style=\"font-variant:small-caps;\">Herrmann, Jan-Phillip</span> ; <span style=\"font-variant:small-caps;\">Tackenberg, Sven</span> ; <span style=\"font-variant:small-caps;\">Brandl, Christopher</span> ; <span style=\"font-variant:small-caps;\">Nitsch , Verena</span>: An error-based augmented reality learning system for work-based occupational safety and health education. In: <i>Work</i> Bd. 72. Amsterdam, IOS Press (2022), Nr. 4, S. 1563–1575","short":"M. Goppold, J.-P. Herrmann, S. Tackenberg, C. Brandl, V. Nitsch , Work 72 (2022) 1563–1575."},"volume":72,"language":[{"iso":"eng"}],"keyword":["Vocational education","digital twin","work system design"],"date_created":"2023-01-25T13:37:17Z","publication_identifier":{"eissn":["1875-9270 "],"issn":["1051-9815"]},"publication":"Work","date_updated":"2024-08-06T11:53:35Z"},{"language":[{"iso":"eng"}],"keyword":["Digital Twin","Asset Administration Shell","Dynamic Simulation Model","Industry 4.0","Automated Model Generation"],"date_created":"2022-06-22T14:14:28Z","publication":"2021 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM)","publication_identifier":{"eisbn":["978-1-6654-3771-4"],"issn":["2157-3611"],"isbn":["978-1-6654-3772-1 "]},"date_updated":"2025-06-26T13:38:36Z","corporate_editor":["IEEE Singapore Section","IEEE TEMS Singapore Chapter,","IEEE TEMS Hong Kong Chapter"],"author":[{"last_name":"Göllner","full_name":"Göllner, D.","first_name":"D."},{"last_name":"Pawlik","full_name":"Pawlik, Thomas","id":"58915","first_name":"Thomas"},{"full_name":"Schulte, Thomas","id":"46242","last_name":"Schulte","first_name":"Thomas"}],"year":"2021","page":"808-812","status":"public","title":"Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models","citation":{"ieee":"D. Göllner, T. Pawlik, and T. Schulte, <i>Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models</i>. [Piscataway, NJ]: IEEE, 2021, pp. 808–812. doi: <a href=\"https://doi.org/10.1109/IEEM50564.2021.9673089\">10.1109/IEEM50564.2021.9673089</a>.","ama":"Göllner D, Pawlik T, Schulte T. <i>Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models</i>. (IEEE Singapore Section, IEEE TEMS Singapore Chapter,, IEEE TEMS Hong Kong Chapter, eds.). IEEE; 2021:808-812. doi:<a href=\"https://doi.org/10.1109/IEEM50564.2021.9673089\">10.1109/IEEM50564.2021.9673089</a>","din1505-2-1":"<span style=\"font-variant:small-caps;\">Göllner, D.</span> ; <span style=\"font-variant:small-caps;\">Pawlik, Thomas</span> ; <span style=\"font-variant:small-caps;\">Schulte, Thomas</span> ; <span style=\"font-variant:small-caps;\">IEEE Singapore Section</span> ; <span style=\"font-variant:small-caps;\">IEEE TEMS Singapore Chapter,</span> ; <span style=\"font-variant:small-caps;\">IEEE TEMS Hong Kong Chapter</span> (Hrsg.): <i>Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models</i>, <i>IEEE International Conference on Industrial Engineering and Engineering Management </i>. [Piscataway, NJ] : IEEE, 2021","chicago-de":"Göllner, D., Thomas Pawlik und Thomas Schulte. 2021. <i>Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models</i>. Hg. von IEEE Singapore Section, IEEE TEMS Singapore Chapter, und IEEE TEMS Hong Kong Chapter. <i>2021 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM)</i>. IEEE International Conference on Industrial Engineering and Engineering Management . [Piscataway, NJ]: IEEE. doi:<a href=\"https://doi.org/10.1109/IEEM50564.2021.9673089\">10.1109/IEEM50564.2021.9673089</a>, .","short":"D. Göllner, T. Pawlik, T. Schulte, Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models, IEEE, [Piscataway, NJ], 2021.","chicago":"Göllner, D., Thomas Pawlik, and Thomas Schulte. <i>Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models</i>. Edited by IEEE Singapore Section, IEEE TEMS Singapore Chapter, and IEEE TEMS Hong Kong Chapter. <i>2021 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM)</i>. IEEE International Conference on Industrial Engineering and Engineering Management . [Piscataway, NJ]: IEEE, 2021. <a href=\"https://doi.org/10.1109/IEEM50564.2021.9673089\">https://doi.org/10.1109/IEEM50564.2021.9673089</a>.","apa":"Göllner, D., Pawlik, T., &#38; Schulte, T. (2021). Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models. In IEEE Singapore Section, IEEE TEMS Singapore Chapter, &#38; IEEE TEMS Hong Kong Chapter (Eds.), <i>2021 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM)</i> (pp. 808–812). IEEE. <a href=\"https://doi.org/10.1109/IEEM50564.2021.9673089\">https://doi.org/10.1109/IEEM50564.2021.9673089</a>","ufg":"<b>Göllner, D./Pawlik, Thomas/Schulte, Thomas</b>: Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models, hg. von IEEE Singapore Section/IEEE TEMS Singapore Chapter,, IEEE TEMS Hong Kong Chapter, [Piscataway, NJ] 2021 (IEEE International Conference on Industrial Engineering and Engineering Management ).","mla":"Göllner, D., et al. “Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models.” <i>2021 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM)</i>, edited by IEEE Singapore Section et al., IEEE, 2021, pp. 808–12, <a href=\"https://doi.org/10.1109/IEEM50564.2021.9673089\">https://doi.org/10.1109/IEEM50564.2021.9673089</a>.","havard":"D. Göllner, T. Pawlik, T. Schulte, Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models, IEEE, [Piscataway, NJ], 2021.","bjps":"<b>Göllner D, Pawlik T and Schulte T</b> (2021) <i>Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models</i>, IEEE Singapore Section, IEEE TEMS Singapore Chapter, and IEEE TEMS Hong Kong Chapter (eds). [Piscataway, NJ]: IEEE.","van":"Göllner D, Pawlik T, Schulte T. Utilization of the Asset Administration Shell for the Generation of Dynamic Simulation Models. IEEE Singapore Section, IEEE TEMS Singapore Chapter,, IEEE TEMS Hong Kong Chapter, editors. 2021 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM). [Piscataway, NJ]: IEEE; 2021. (IEEE International Conference on Industrial Engineering and Engineering Management )."},"place":"[Piscataway, NJ]","doi":"10.1109/IEEM50564.2021.9673089","_id":"8384","type":"conference_editor_article","user_id":"83781","conference":{"end_date":"2021-12-16","start_date":"2021-12-13","location":"Online  (Singapore)","name":"2021 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM)"},"department":[{"_id":"DEP6020"},{"_id":"DEP5022"}],"abstract":[{"lang":"eng","text":"ynamic simulation models are widely utilized to evaluate complex technical components and systems like electric drives or machines. They can support the development process of a production machine by avoiding an inadequate layout of components or an erroneous control design. However, the effort for building them is often too high for this purpose (lot size one). An automated model generation can be utilized to overcome the gap between efforts and advantages of dynamic simulations.\r\n\r\nThis contribution presents an approach for simplifying the dynamic model generation of production machines by using the so-called Asset Administration Shell defined by the initiative Platform Industrie 4.0. The Asset Administration Shell was developed to aggregate all data necessary for maintaining the product across its life cycle. This includes component data and models as well as structural information about a machine. The generation process is performed by using the common FMI standard and a two-step procedure which allows the linkage of different simulation tools. The model generation is demonstrated by an example layout of a machine's internal direct current grid."}],"publisher":"IEEE","series_title":"IEEE International Conference on Industrial Engineering and Engineering Management ","publication_status":"published"},{"title":"Digital Seed Train Twins and Statistical Methods","volume":176,"citation":{"ufg":"<b>Hernández Rodriguez, Tanja/Frahm, Björn</b>: Digital Seed Train Twins and Statistical Methods, in: <i>Herwig, Christoph/Pörtner, Ralf/Möller, Johannes (Hgg.)</i>: Digital Twins Tools and Concepts for Smart Biomanufacturing, Bd. 176, Berlin, Heidelberg 2021 (Advances in Biochemical Engineering/Biotechnology),  S. 97–131.","bjps":"<b>Hernández Rodriguez T and Frahm B</b> (2021) Digital Seed Train Twins and Statistical Methods. In Herwig C, Pörtner R and Möller J (eds), <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i>, vol. 176. Berlin, Heidelberg: Springer, pp. 97–131.","havard":"T. Hernández Rodriguez, B. Frahm, Digital Seed Train Twins and Statistical Methods, in: C. Herwig, R. Pörtner, J. Möller (Eds.), Digital Twins Tools and Concepts for Smart Biomanufacturing, Springer, Berlin, Heidelberg, 2021: pp. 97–131.","mla":"Hernández Rodriguez, Tanja, and Björn Frahm. “Digital Seed Train Twins and Statistical Methods.” <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i>, edited by Christoph  Herwig et al., vol. 176, Springer, 2021, pp. 97–131, <a href=\"https://doi.org/10.1007/10_2020_137\">https://doi.org/10.1007/10_2020_137</a>.","van":"Hernández Rodriguez T, Frahm B. Digital Seed Train Twins and Statistical Methods. In: Herwig C, Pörtner R, Möller J, editors. Digital Twins Tools and Concepts for Smart Biomanufacturing. Berlin, Heidelberg: Springer; 2021. p. 97–131. (Advances in Biochemical Engineering/Biotechnology; vol. 176).","chicago":"Hernández Rodriguez, Tanja, and Björn Frahm. “Digital Seed Train Twins and Statistical Methods.” In <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i>, edited by Christoph  Herwig, Ralf  Pörtner, and Johannes  Möller, 176:97–131. Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer, 2021. <a href=\"https://doi.org/10.1007/10_2020_137\">https://doi.org/10.1007/10_2020_137</a>.","apa":"Hernández Rodriguez, T., &#38; Frahm, B. (2021). Digital Seed Train Twins and Statistical Methods. In C. Herwig, R. Pörtner, &#38; J. Möller (Eds.), <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i> (Vol. 176, pp. 97–131). Springer. <a href=\"https://doi.org/10.1007/10_2020_137\">https://doi.org/10.1007/10_2020_137</a>","din1505-2-1":"<span style=\"font-variant:small-caps;\">Hernández Rodriguez, Tanja</span> ; <span style=\"font-variant:small-caps;\">Frahm, Björn</span>: Digital Seed Train Twins and Statistical Methods. In: <span style=\"font-variant:small-caps;\">Herwig, C.</span> ; <span style=\"font-variant:small-caps;\">Pörtner, R.</span> ; <span style=\"font-variant:small-caps;\">Möller, J.</span> (Hrsg.): <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i>, <i>Advances in Biochemical Engineering/Biotechnology</i>. Bd. 176. Berlin, Heidelberg : Springer, 2021, S. 97–131","chicago-de":"Hernández Rodriguez, Tanja und Björn Frahm. 2021. Digital Seed Train Twins and Statistical Methods. In: <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i>, hg. von Christoph  Herwig, Ralf  Pörtner, und Johannes  Möller, 176:97–131. Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer. doi:<a href=\"https://doi.org/10.1007/10_2020_137\">https://doi.org/10.1007/10_2020_137</a>, .","short":"T. Hernández Rodriguez, B. Frahm, in: C. Herwig, R. Pörtner, J. Möller (Eds.), Digital Twins Tools and Concepts for Smart Biomanufacturing, Springer, Berlin, Heidelberg, 2021, pp. 97–131.","ama":"Hernández Rodriguez T, Frahm B. Digital Seed Train Twins and Statistical Methods. In: Herwig C, Pörtner R, Möller J, eds. <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i>. Vol 176. Advances in Biochemical Engineering/Biotechnology. Springer; 2021:97-131. doi:<a href=\"https://doi.org/10.1007/10_2020_137\">https://doi.org/10.1007/10_2020_137</a>","ieee":"T. Hernández Rodriguez and B. Frahm, “Digital Seed Train Twins and Statistical Methods,” in <i>Digital Twins Tools and Concepts for Smart Biomanufacturing</i>, vol. 176, C. Herwig, R. Pörtner, and J. Möller, Eds. Berlin, Heidelberg: Springer, 2021, pp. 97–131. doi: <a href=\"https://doi.org/10.1007/10_2020_137\">https://doi.org/10.1007/10_2020_137</a>."},"author":[{"last_name":"Hernández Rodriguez","id":"52466","full_name":"Hernández Rodriguez, Tanja","first_name":"Tanja"},{"id":"45666","first_name":"Björn","full_name":"Frahm, Björn","last_name":"Frahm"}],"year":"2021","status":"public","page":"97–131","publication":"Digital Twins Tools and Concepts for Smart Biomanufacturing","publication_identifier":{"eisbn":["978-3-030-71660-8"],"issn":["0724-6145"],"eissn":["1616-8542"],"isbn":["978-3-030-71659-2"]},"date_created":"2020-08-19T07:14:11Z","date_updated":"2023-08-16T06:48:35Z","editor":[{"last_name":"Herwig","first_name":"Christoph ","full_name":"Herwig, Christoph "},{"first_name":"Ralf ","last_name":"Pörtner","full_name":"Pörtner, Ralf "},{"first_name":"Johannes ","last_name":"Möller","full_name":"Möller, Johannes "}],"keyword":["Bayes","Digital twin","Parameter estimation","Seed train","Uncertainty"],"language":[{"iso":"eng"}],"series_title":"Advances in Biochemical Engineering/Biotechnology","publication_status":"published","department":[{"_id":"DEP4021"}],"abstract":[{"text":"Model-based concepts and simulation techniques in combination with digital tools emerge as a key to explore the full potential of biopharmaceutical production processes, which contain several challenging development and process steps. One of these steps is the time- and cost-intensive cell proliferation process (also called seed train) to increase cell number from cell thawing up to production scale. Challenges like complex cell metabolism, batch-to-batch variation, variabilities in cell behavior, and influences of changes in cultivation conditions necessitate adequate digital solutions to provide information about the current and near future process state to derive correct process decisions.\r\nFor this purpose digital seed train twins have proved to be efficient, which digitally display the time-dependent behavior of important process variables based on mathematical models, strategies, and adaption procedures.\r\nThis chapter will outline the needs for digitalization of seed trains, the construction of a digital seed train twin, the role of parameter estimation, and different statistical methods within this context, which are applicable to several problems in the field of bioprocessing. The results of a case study are presented to illustrate a Bayesian approach for parameter estimation and prediction of an industrial cell culture seed train for seed train digitalization.","lang":"eng"}],"publisher":"Springer","quality_controlled":"1","type":"book_chapter","user_id":"83781","intvolume":"       176","place":"Berlin, Heidelberg","_id":"3349","doi":"https://doi.org/10.1007/10_2020_137"}]