---
_id: '12966'
abstract:
- lang: eng
  text: 'The fungus Stachybotrys (S.) chartarum was isolated from culinary herbs,
    damp building materials, and improperly stored animal forage. Two distinct chemotypes
    of the fungus were described that produced either high-cytotoxic macrocyclic trichothecenes
    (S type) or low-cytotoxic atranones (A type). Recently, two distinct gene clusters
    were described that were found to be necessary for the biosynthesis of either
    macrocyclic trichothecenes (21 SAT (Satratoxin) genes) or atranones (14 ATR (Atranone)
    genes). In the current study, PCR primers were designed to detect SAT and ATR
    genes in 19 S. chartarum chemotype S and eight S. chartarum chemotype A strains.
    Our analysis revealed the existence of three different genotypes: satratoxin-producing
    strains that harbored all SAT genes but lacked the ATR gene cluster (genotype
    S), non-satratoxin-producing strains that possessed the ATR genes but lacked SAT
    genes (genotype A), and a hitherto undescribed hybrid genotype among non-satratoxin-producing
    strains that harbored all ATR genes and an incomplete set of SAT genes (genotype
    H). In order to improve the discrimination of genotypes, a triplex PCR assay was
    developed and applied for the analysis of S. chartarum and S. chlorohalonata cultures.
    The results show that genes for macrocyclic trichothecenes and atranones are not
    mutually exclusive in S. chartarum. Correlation of the new genotype-based concept
    with mycotoxin production data shows also that macrocyclic trichothecenes are
    exclusively produced by S. chartarum genotype S strains.'
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Ludwig
  full_name: Niessen, Ludwig
  last_name: Niessen
- first_name: Julia
  full_name: Ekruth, Julia
  last_name: Ekruth
- first_name: Cornelius
  full_name: Schäfer, Cornelius
  last_name: Schäfer
- first_name: Florian
  full_name: Kaltner, Florian
  last_name: Kaltner
- first_name: Christoph
  full_name: Gottschalk, Christoph
  last_name: Gottschalk
citation:
  ama: Ulrich S, Niessen L, Ekruth J, Schäfer C, Kaltner F, Gottschalk C. Truncated
    satratoxin gene clusters in selected isolates of the atranone chemotype of Stachybotrys
    chartarum (Ehrenb.) S. Hughes. <i>Mycotoxin Research</i>. 2019;36(1):83-91. doi:<a
    href="https://doi.org/10.1007/s12550-019-00371-x">10.1007/s12550-019-00371-x</a>
  apa: Ulrich, S., Niessen, L., Ekruth, J., Schäfer, C., Kaltner, F., &#38; Gottschalk,
    C. (2019). Truncated satratoxin gene clusters in selected isolates of the atranone
    chemotype of Stachybotrys chartarum (Ehrenb.) S. Hughes. <i>Mycotoxin Research</i>,
    <i>36</i>(1), 83–91. <a href="https://doi.org/10.1007/s12550-019-00371-x">https://doi.org/10.1007/s12550-019-00371-x</a>
  bjps: <b>Ulrich S <i>et al.</i></b> (2019) Truncated Satratoxin Gene Clusters in
    Selected Isolates of the Atranone Chemotype of Stachybotrys Chartarum (Ehrenb.)
    S. Hughes. <i>Mycotoxin Research</i> <b>36</b>, 83–91.
  chicago: 'Ulrich, Sebastian, Ludwig Niessen, Julia Ekruth, Cornelius Schäfer, Florian
    Kaltner, and Christoph Gottschalk. “Truncated Satratoxin Gene Clusters in Selected
    Isolates of the Atranone Chemotype of Stachybotrys Chartarum (Ehrenb.) S. Hughes.”
    <i>Mycotoxin Research</i> 36, no. 1 (2019): 83–91. <a href="https://doi.org/10.1007/s12550-019-00371-x">https://doi.org/10.1007/s12550-019-00371-x</a>.'
  chicago-de: 'Ulrich, Sebastian, Ludwig Niessen, Julia Ekruth, Cornelius Schäfer,
    Florian Kaltner und Christoph Gottschalk. 2019. Truncated satratoxin gene clusters
    in selected isolates of the atranone chemotype of Stachybotrys chartarum (Ehrenb.)
    S. Hughes. <i>Mycotoxin Research</i> 36, Nr. 1: 83–91. doi:<a href="https://doi.org/10.1007/s12550-019-00371-x">10.1007/s12550-019-00371-x</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Ulrich, Sebastian</span> ;
    <span style="font-variant:small-caps;">Niessen, Ludwig</span> ; <span style="font-variant:small-caps;">Ekruth,
    Julia</span> ; <span style="font-variant:small-caps;">Schäfer, Cornelius</span>
    ; <span style="font-variant:small-caps;">Kaltner, Florian</span> ; <span style="font-variant:small-caps;">Gottschalk,
    Christoph</span>: Truncated satratoxin gene clusters in selected isolates of the
    atranone chemotype of Stachybotrys chartarum (Ehrenb.) S. Hughes. In: <i>Mycotoxin
    Research</i> Bd. 36. Berlin ; Heidelberg, Springer (2019), Nr. 1, S. 83–91'
  havard: S. Ulrich, L. Niessen, J. Ekruth, C. Schäfer, F. Kaltner, C. Gottschalk,
    Truncated satratoxin gene clusters in selected isolates of the atranone chemotype
    of Stachybotrys chartarum (Ehrenb.) S. Hughes, Mycotoxin Research. 36 (2019) 83–91.
  ieee: 'S. Ulrich, L. Niessen, J. Ekruth, C. Schäfer, F. Kaltner, and C. Gottschalk,
    “Truncated satratoxin gene clusters in selected isolates of the atranone chemotype
    of Stachybotrys chartarum (Ehrenb.) S. Hughes,” <i>Mycotoxin Research</i>, vol.
    36, no. 1, pp. 83–91, 2019, doi: <a href="https://doi.org/10.1007/s12550-019-00371-x">10.1007/s12550-019-00371-x</a>.'
  mla: Ulrich, Sebastian, et al. “Truncated Satratoxin Gene Clusters in Selected Isolates
    of the Atranone Chemotype of Stachybotrys Chartarum (Ehrenb.) S. Hughes.” <i>Mycotoxin
    Research</i>, vol. 36, no. 1, 2019, pp. 83–91, <a href="https://doi.org/10.1007/s12550-019-00371-x">https://doi.org/10.1007/s12550-019-00371-x</a>.
  short: S. Ulrich, L. Niessen, J. Ekruth, C. Schäfer, F. Kaltner, C. Gottschalk,
    Mycotoxin Research 36 (2019) 83–91.
  ufg: '<b>Ulrich, Sebastian u. a.</b>: Truncated satratoxin gene clusters in selected
    isolates of the atranone chemotype of Stachybotrys chartarum (Ehrenb.) S. Hughes,
    in: <i>Mycotoxin Research</i> 36 (2019), H. 1,  S. 83–91.'
  van: Ulrich S, Niessen L, Ekruth J, Schäfer C, Kaltner F, Gottschalk C. Truncated
    satratoxin gene clusters in selected isolates of the atranone chemotype of Stachybotrys
    chartarum (Ehrenb.) S. Hughes. Mycotoxin Research. 2019;36(1):83–91.
date_created: 2025-06-15T10:19:53Z
date_updated: 2025-06-18T11:20:11Z
department:
- _id: DEP4010
doi: 10.1007/s12550-019-00371-x
extern: '1'
intvolume: '        36'
issue: '1'
keyword:
- Acetyltransferases
- Chlamydomonas reinhardtii
- Fungal Genes
- Fungal genetics
- Fungal genomics
- Saccharomyces cerevisiae
language:
- iso: eng
page: 83-91
place: Berlin ; Heidelberg
publication: Mycotoxin Research
publication_identifier:
  eissn:
  - 1867-1632
  issn:
  - 0178-7888
publication_status: published
publisher: Springer
quality_controlled: '1'
status: public
title: Truncated satratoxin gene clusters in selected isolates of the atranone chemotype
  of Stachybotrys chartarum (Ehrenb.) S. Hughes
type: scientific_journal_article
user_id: '83781'
volume: 36
year: '2019'
...