---
_id: '12953'
abstract:
- lang: eng
  text: Starch gelatinization is a major determinant of carbohydrate digestibility
    and varies with diet processing. Laboratory rodent diets are often marketed as
    identical, but are sold in different forms, regardless of the markedly higher
    starch gelatinization in extruded than in pelleted diets. Our hypothesis was that
    this would impact energy and nutrient digestibility in mice fed pellets or extrudate,
    respectively. Trial 1 showed that feeding C57BL/6 mice a standard maintenance
    diet in extruded form results in a significantly higher digestibility of organic
    matter, energy, and carbohydrates than the identical diet in pelleted form. The
    replication of the experiment, however, revealed a variation between batches of
    the same pelleted diet regarding starch and total dietary fiber contents. Given
    the significant differences in diet digestibility and the potential impacts of
    digestibility on nutrient utilization, the intestinal microbiome, and intermediary
    metabolism, trials performed with differently processed diets are not comparable.
    This might partly explain failures to reproduce results, especially in gastrointestinal
    or microbiome research. Considering this impact on experimental animals, the degree
    of starch gelatinization should be declared in the diet information for laboratory
    animal diets. The differences between batches of laboratory animal diets as observed
    in the pellets are not acceptable.
article_number: '523'
author:
- first_name: Linda F.
  full_name: Böswald, Linda F.
  last_name: Böswald
- first_name: Jasmin
  full_name: Wenderlein, Jasmin
  last_name: Wenderlein
- first_name: Reinhard K.
  full_name: Straubinger, Reinhard K.
  last_name: Straubinger
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Ellen
  full_name: Kienzle, Ellen
  last_name: Kienzle
citation:
  ama: Böswald LF, Wenderlein J, Straubinger RK, Ulrich S, Kienzle E. Processing Matters
    in Nutrient-Matched Laboratory Diets for Mice—Energy and Nutrient Digestibility.
    <i>Animals</i>. 2021;11(2). doi:<a href="https://doi.org/10.3390/ani11020523">10.3390/ani11020523</a>
  apa: Böswald, L. F., Wenderlein, J., Straubinger, R. K., Ulrich, S., &#38; Kienzle,
    E. (2021). Processing Matters in Nutrient-Matched Laboratory Diets for Mice—Energy
    and Nutrient Digestibility. <i>Animals</i>, <i>11</i>(2), Article 523. <a href="https://doi.org/10.3390/ani11020523">https://doi.org/10.3390/ani11020523</a>
  bjps: <b>Böswald LF <i>et al.</i></b> (2021) Processing Matters in Nutrient-Matched
    Laboratory Diets for Mice—Energy and Nutrient Digestibility. <i>Animals</i> <b>11</b>.
  chicago: Böswald, Linda F., Jasmin Wenderlein, Reinhard K. Straubinger, Sebastian
    Ulrich, and Ellen Kienzle. “Processing Matters in Nutrient-Matched Laboratory
    Diets for Mice—Energy and Nutrient Digestibility.” <i>Animals</i> 11, no. 2 (2021).
    <a href="https://doi.org/10.3390/ani11020523">https://doi.org/10.3390/ani11020523</a>.
  chicago-de: Böswald, Linda F., Jasmin Wenderlein, Reinhard K. Straubinger, Sebastian
    Ulrich und Ellen Kienzle. 2021. Processing Matters in Nutrient-Matched Laboratory
    Diets for Mice—Energy and Nutrient Digestibility. <i>Animals</i> 11, Nr. 2. doi:<a
    href="https://doi.org/10.3390/ani11020523">10.3390/ani11020523</a>, .
  din1505-2-1: '<span style="font-variant:small-caps;">Böswald, Linda F.</span> ;
    <span style="font-variant:small-caps;">Wenderlein, Jasmin</span> ; <span style="font-variant:small-caps;">Straubinger,
    Reinhard K.</span> ; <span style="font-variant:small-caps;">Ulrich, Sebastian</span>
    ; <span style="font-variant:small-caps;">Kienzle, Ellen</span>: Processing Matters
    in Nutrient-Matched Laboratory Diets for Mice—Energy and Nutrient Digestibility.
    In: <i>Animals</i> Bd. 11. Basel, MDPI (2021), Nr. 2'
  havard: L.F. Böswald, J. Wenderlein, R.K. Straubinger, S. Ulrich, E. Kienzle, Processing
    Matters in Nutrient-Matched Laboratory Diets for Mice—Energy and Nutrient Digestibility,
    Animals. 11 (2021).
  ieee: 'L. F. Böswald, J. Wenderlein, R. K. Straubinger, S. Ulrich, and E. Kienzle,
    “Processing Matters in Nutrient-Matched Laboratory Diets for Mice—Energy and Nutrient
    Digestibility,” <i>Animals</i>, vol. 11, no. 2, Art. no. 523, 2021, doi: <a href="https://doi.org/10.3390/ani11020523">10.3390/ani11020523</a>.'
  mla: Böswald, Linda F., et al. “Processing Matters in Nutrient-Matched Laboratory
    Diets for Mice—Energy and Nutrient Digestibility.” <i>Animals</i>, vol. 11, no.
    2, 523, 2021, <a href="https://doi.org/10.3390/ani11020523">https://doi.org/10.3390/ani11020523</a>.
  short: L.F. Böswald, J. Wenderlein, R.K. Straubinger, S. Ulrich, E. Kienzle, Animals
    11 (2021).
  ufg: '<b>Böswald, Linda F. u. a.</b>: Processing Matters in Nutrient-Matched Laboratory
    Diets for Mice—Energy and Nutrient Digestibility, in: <i>Animals</i> 11 (2021),
    H. 2.'
  van: Böswald LF, Wenderlein J, Straubinger RK, Ulrich S, Kienzle E. Processing Matters
    in Nutrient-Matched Laboratory Diets for Mice—Energy and Nutrient Digestibility.
    Animals. 2021;11(2).
date_created: 2025-06-15T10:00:16Z
date_updated: 2025-06-16T12:27:09Z
department:
- _id: DEP4010
doi: 10.3390/ani11020523
extern: '1'
intvolume: '        11'
issue: '2'
keyword:
- standardization
- carbohydrate digestibility
- feed processing
- starch gelatinization
- gut
language:
- iso: eng
place: Basel
publication: Animals
publication_identifier:
  eissn:
  - 2076-2615
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Processing Matters in Nutrient-Matched Laboratory Diets for Mice—Energy and
  Nutrient Digestibility
type: scientific_journal_article
user_id: '83781'
volume: 11
year: '2021'
...
---
_id: '4756'
abstract:
- lang: eng
  text: Due to the dynamic nature of the Industrie 4.0 developments, future production
    systems will be reconfigured more frequently and new system configurations will
    be deployed automatically. In order to keep pace with this development, it will
    be required to observe and ensure the needed security functionalities and corresponding
    certifications in an automated way. This implies an improvement of today's static
    procedures and manual efforts as much as possible in favor of a dynamic standard
    establishment. Therefore, this paper evaluates the state of the art of the industrial
    security standardization landscape and proposes a concept for the automated support
    of certification processes with information from industrial communication networks
    in order to enhance the usability of the standards establishments and the certifications
    within organizations and companies, especially small and medium-sized enterprises.
author:
- first_name: Marco
  full_name: Ehrlich, Marco
  id: '61562'
  last_name: Ehrlich
- first_name: Henning
  full_name: Trsek, Henning
  id: '1486'
  last_name: Trsek
  orcid: 0000-0002-0133-0656
- first_name: Lukasz
  full_name: Wisniewski, Lukasz
  id: '1710'
  last_name: Wisniewski
- first_name: Jürgen
  full_name: Jasperneite, Jürgen
  id: '1899'
  last_name: Jasperneite
citation:
  ama: 'Ehrlich M, Trsek H, Wisniewski L, Jasperneite J. Survey of Security Standards
    for an automated Industrie 4.0 compatible Manufacturing. In:  IEEE Industrial
    Electronics Society. Annual Conference , IEEE Industrial Electronics Society ,
    Universidade Nova de Lisboa , Institute of Electrical and Electronics Engineers,
    eds. <i>IECON 2019 - 45th Annual Conference of the IEEE Industrial Electronics
    Society (IES)</i>. IEEE Industrial Electronics Society. IEEE; 2019:2849-2854.'
  apa: Ehrlich, M., Trsek, H., Wisniewski, L., &#38; Jasperneite, J. (2019). Survey
    of Security Standards for an automated Industrie 4.0 compatible Manufacturing.
    In  IEEE Industrial Electronics Society. Annual Conference , IEEE Industrial Electronics
    Society , Universidade Nova de Lisboa , &#38; Institute of Electrical and Electronics
    Engineers (Eds.), <i>IECON 2019 - 45th Annual Conference of the IEEE Industrial
    Electronics Society (IES)</i> (pp. 2849–2854). IEEE.
  bjps: '<b>Ehrlich M <i>et al.</i></b> (2019) Survey of Security Standards for an
    Automated Industrie 4.0 Compatible Manufacturing. In  IEEE Industrial Electronics
    Society. Annual Conference  et al. (eds), <i>IECON 2019 - 45th Annual Conference
    of the IEEE Industrial Electronics Society (IES)</i>. [Piscataway, NJ]: IEEE,
    pp. 2849–2854.'
  chicago: 'Ehrlich, Marco, Henning Trsek, Lukasz Wisniewski, and Jürgen Jasperneite.
    “Survey of Security Standards for an Automated Industrie 4.0 Compatible Manufacturing.”
    In <i>IECON 2019 - 45th Annual Conference of the IEEE Industrial Electronics Society
    (IES)</i>, edited by  IEEE Industrial Electronics Society. Annual Conference ,
    IEEE Industrial Electronics Society , Universidade Nova de Lisboa , and Institute
    of Electrical and Electronics Engineers, 2849–54. IEEE Industrial Electronics
    Society. [Piscataway, NJ]: IEEE, 2019.'
  chicago-de: 'Ehrlich, Marco, Henning Trsek, Lukasz Wisniewski und Jürgen Jasperneite.
    2019. Survey of Security Standards for an automated Industrie 4.0 compatible Manufacturing.
    In: <i>IECON 2019 - 45th Annual Conference of the IEEE Industrial Electronics
    Society (IES)</i>, hg. von  IEEE Industrial Electronics Society. Annual Conference
    , IEEE Industrial Electronics Society , Universidade Nova de Lisboa , und Institute
    of Electrical and Electronics Engineers, 2849–2854. IEEE Industrial Electronics
    Society. [Piscataway, NJ]: IEEE.'
  din1505-2-1: '<span style="font-variant:small-caps;">Ehrlich, Marco</span> ; <span
    style="font-variant:small-caps;">Trsek, Henning</span> ; <span style="font-variant:small-caps;">Wisniewski,
    Lukasz</span> ; <span style="font-variant:small-caps;">Jasperneite, Jürgen</span>:
    Survey of Security Standards for an automated Industrie 4.0 compatible Manufacturing.
    In: <span style="font-variant:small-caps;"> IEEE Industrial Electronics Society.
    Annual Conference </span> ; <span style="font-variant:small-caps;">IEEE Industrial
    Electronics Society </span> ; <span style="font-variant:small-caps;">Universidade
    Nova de Lisboa </span> ; <span style="font-variant:small-caps;">Institute of Electrical
    and Electronics Engineers</span> (Hrsg.): <i>IECON 2019 - 45th Annual Conference
    of the IEEE Industrial Electronics Society (IES)</i>, <i>IEEE Industrial Electronics
    Society</i>. [Piscataway, NJ] : IEEE, 2019, S. 2849–2854'
  havard: 'M. Ehrlich, H. Trsek, L. Wisniewski, J. Jasperneite, Survey of Security
    Standards for an automated Industrie 4.0 compatible Manufacturing, in:  IEEE Industrial
    Electronics Society. Annual Conference , IEEE Industrial Electronics Society ,
    Universidade Nova de Lisboa , Institute of Electrical and Electronics Engineers
    (Eds.), IECON 2019 - 45th Annual Conference of the IEEE Industrial Electronics
    Society (IES), IEEE, [Piscataway, NJ], 2019: pp. 2849–2854.'
  ieee: M. Ehrlich, H. Trsek, L. Wisniewski, and J. Jasperneite, “Survey of Security
    Standards for an automated Industrie 4.0 compatible Manufacturing,” in <i>IECON
    2019 - 45th Annual Conference of the IEEE Industrial Electronics Society (IES)</i>,
    Lisbon, PORTUGAL, 2019, pp. 2849–2854.
  mla: Ehrlich, Marco, et al. “Survey of Security Standards for an Automated Industrie
    4.0 Compatible Manufacturing.” <i>IECON 2019 - 45th Annual Conference of the IEEE
    Industrial Electronics Society (IES)</i>, edited by  IEEE Industrial Electronics
    Society. Annual Conference  et al., IEEE, 2019, pp. 2849–54.
  short: 'M. Ehrlich, H. Trsek, L. Wisniewski, J. Jasperneite, in:  IEEE Industrial
    Electronics Society. Annual Conference , IEEE Industrial Electronics Society ,
    Universidade Nova de Lisboa , Institute of Electrical and Electronics Engineers
    (Eds.), IECON 2019 - 45th Annual Conference of the IEEE Industrial Electronics
    Society (IES), IEEE, [Piscataway, NJ], 2019, pp. 2849–2854.'
  ufg: '<b>Ehrlich, Marco u. a.</b>: Survey of Security Standards for an automated
    Industrie 4.0 compatible Manufacturing, in: <i> IEEE Industrial Electronics Society.
    Annual Conference  u. a. (Hgg.)</i>: IECON 2019 - 45th Annual Conference of the
    IEEE Industrial Electronics Society (IES), [Piscataway, NJ] 2019 (IEEE Industrial
    Electronics Society),  S. 2849–2854.'
  van: 'Ehrlich M, Trsek H, Wisniewski L, Jasperneite J. Survey of Security Standards
    for an automated Industrie 4.0 compatible Manufacturing. In:  IEEE Industrial
    Electronics Society. Annual Conference , IEEE Industrial Electronics Society ,
    Universidade Nova de Lisboa , Institute of Electrical and Electronics Engineers,
    editors. IECON 2019 - 45th Annual Conference of the IEEE Industrial Electronics
    Society (IES). [Piscataway, NJ]: IEEE; 2019. p. 2849–54. (IEEE Industrial Electronics
    Society).'
conference:
  end_date: 2019-10-19
  location: Lisbon, PORTUGAL
  name: 45th Annual Conference of the IEEE Industrial Electronics Society (IECON)
  start_date: 2019-10-14
corporate_editor:
- ' IEEE Industrial Electronics Society. Annual Conference '
- 'IEEE Industrial Electronics Society '
- 'Universidade Nova de Lisboa '
- Institute of Electrical and Electronics Engineers
date_created: 2021-01-28T14:47:12Z
date_updated: 2025-06-26T13:31:27Z
department:
- _id: DEP5023
- _id: DEP5019
keyword:
- Industrial Automation
- Security
- Toolchain
- Standardization
- Communication Networks
language:
- iso: eng
page: 2849-2854
place: '[Piscataway, NJ]'
publication: IECON 2019 - 45th Annual Conference of the IEEE Industrial Electronics
  Society (IES)
publication_identifier:
  eisbn:
  - 978-1-7281-4878-6
  isbn:
  - 978-1-7281-4879-3
  issn:
  - 1553-572X
publication_status: published
publisher: IEEE
series_title: IEEE Industrial Electronics Society
status: public
title: Survey of Security Standards for an automated Industrie 4.0 compatible Manufacturing
type: conference
user_id: '83781'
year: '2019'
...
