---
_id: '12979'
abstract:
- lang: eng
  text: Physiological consequences of adaptation to and continued feeding of a high-energetic
    diet were studied in eight non-pregnant, non-lactating dairy Holstein cows over
    a period of 16 weeks. The first six weeks served as an adaptation period from
    the low energetic straw-based diet (3.8 MJ NEL/kg DM) to the high-energetic ration
    (7.5 MJ NEL/kg DM). Intake of dry matter (DM) increased with dietary energy concentration
    from 9 to 20 kg/d up to week 9 to 12 and decreased thereafter. The initial live
    weight (LW) of 550 ± 60 kg was increased linearly and corresponded to an average
    daily LW gain of 2.3 ± 0.3 kg. Energy balance increased approximately nine-fold
    to a maximum of 114 MJ NEL/d in week 10. Ruminal fermentation pattern was completely
    changed from an acetate dominating profile to a propionate based one, which was
    paralleled by a marked increase in the rumen fluid endotoxin concentration. Unlike
    blood glucose concentration, which increased continuously, that of cholesterol
    and triglycerides started to increase after an initial stagnation. In conclusion,
    both ruminal adaptation to a high-energetic diet and the continued feeding of
    such a diet induced digestive and metabolic adaptations in non-pregnant, non-lactating
    cows characterised by a progressing positive energy balance.
author:
- first_name: Sven
  full_name: Dänicke, Sven
  last_name: Dänicke
- first_name: Ulrich
  full_name: Meyer, Ulrich
  last_name: Meyer
- first_name: Janine
  full_name: Winkler, Janine
  last_name: Winkler
- first_name: Kirsten
  full_name: Schulz, Kirsten
  last_name: Schulz
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Jana
  full_name: Frahm, Jana
  last_name: Frahm
- first_name: Susanne
  full_name: Kersten, Susanne
  last_name: Kersten
- first_name: Jürgen
  full_name: Rehage, Jürgen
  last_name: Rehage
- first_name: Gerhard
  full_name: Breves, Gerhard
  last_name: Breves
- first_name: Susanne
  full_name: Häußler, Susanne
  last_name: Häußler
- first_name: Helga
  full_name: Sauerwein, Helga
  last_name: Sauerwein
- first_name: Lena
  full_name: Locher, Lena
  last_name: Locher
citation:
  ama: Dänicke S, Meyer U, Winkler J, et al. Description of a bovine model for studying
    digestive and metabolic effects of a positive energy balance not biased by lactation
    or gravidity. <i>Archives of Animal Nutrition</i>. 2014;68(6):460-477. doi:<a
    href="https://doi.org/10.1080/1745039x.2014.973243">10.1080/1745039x.2014.973243</a>
  apa: Dänicke, S., Meyer, U., Winkler, J., Schulz, K., Ulrich, S., Frahm, J., Kersten,
    S., Rehage, J., Breves, G., Häußler, S., Sauerwein, H., &#38; Locher, L. (2014).
    Description of a bovine model for studying digestive and metabolic effects of
    a positive energy balance not biased by lactation or gravidity. <i>Archives of
    Animal Nutrition</i>, <i>68</i>(6), 460–477. <a href="https://doi.org/10.1080/1745039x.2014.973243">https://doi.org/10.1080/1745039x.2014.973243</a>
  bjps: <b>Dänicke S <i>et al.</i></b> (2014) Description of a Bovine Model for Studying
    Digestive and Metabolic Effects of a Positive Energy Balance Not Biased by Lactation
    or Gravidity. <i>Archives of Animal Nutrition</i> <b>68</b>, 460–477.
  chicago: 'Dänicke, Sven, Ulrich Meyer, Janine Winkler, Kirsten Schulz, Sebastian
    Ulrich, Jana Frahm, Susanne Kersten, et al. “Description of a Bovine Model for
    Studying Digestive and Metabolic Effects of a Positive Energy Balance Not Biased
    by Lactation or Gravidity.” <i>Archives of Animal Nutrition</i> 68, no. 6 (2014):
    460–77. <a href="https://doi.org/10.1080/1745039x.2014.973243">https://doi.org/10.1080/1745039x.2014.973243</a>.'
  chicago-de: 'Dänicke, Sven, Ulrich Meyer, Janine Winkler, Kirsten Schulz, Sebastian
    Ulrich, Jana Frahm, Susanne Kersten, u. a. 2014. Description of a bovine model
    for studying digestive and metabolic effects of a positive energy balance not
    biased by lactation or gravidity. <i>Archives of Animal Nutrition</i> 68, Nr.
    6: 460–477. doi:<a href="https://doi.org/10.1080/1745039x.2014.973243">10.1080/1745039x.2014.973243</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;"><span style="font-variant:small-caps;">Dänicke,
    Sven</span> ; <span style="font-variant:small-caps;">Meyer, Ulrich</span> ; <span
    style="font-variant:small-caps;">Winkler, Janine</span> ; <span style="font-variant:small-caps;">Schulz,
    Kirsten</span> ; <span style="font-variant:small-caps;">Ulrich, Sebastian</span>
    ; <span style="font-variant:small-caps;">Frahm, Jana</span> ; <span style="font-variant:small-caps;">Kersten,
    Susanne</span> ; <span style="font-variant:small-caps;">Rehage, Jürgen</span>
    ; u. a.</span>: Description of a bovine model for studying digestive and metabolic
    effects of a positive energy balance not biased by lactation or gravidity. In:
    <i>Archives of Animal Nutrition</i> Bd. 68. Abingdon, Taylor &#38; Francis (2014),
    Nr. 6, S. 460–477'
  havard: S. Dänicke, U. Meyer, J. Winkler, K. Schulz, S. Ulrich, J. Frahm, S. Kersten,
    J. Rehage, G. Breves, S. Häußler, H. Sauerwein, L. Locher, Description of a bovine
    model for studying digestive and metabolic effects of a positive energy balance
    not biased by lactation or gravidity, Archives of Animal Nutrition. 68 (2014)
    460–477.
  ieee: 'S. Dänicke <i>et al.</i>, “Description of a bovine model for studying digestive
    and metabolic effects of a positive energy balance not biased by lactation or
    gravidity,” <i>Archives of Animal Nutrition</i>, vol. 68, no. 6, pp. 460–477,
    2014, doi: <a href="https://doi.org/10.1080/1745039x.2014.973243">10.1080/1745039x.2014.973243</a>.'
  mla: Dänicke, Sven, et al. “Description of a Bovine Model for Studying Digestive
    and Metabolic Effects of a Positive Energy Balance Not Biased by Lactation or
    Gravidity.” <i>Archives of Animal Nutrition</i>, vol. 68, no. 6, 2014, pp. 460–77,
    <a href="https://doi.org/10.1080/1745039x.2014.973243">https://doi.org/10.1080/1745039x.2014.973243</a>.
  short: S. Dänicke, U. Meyer, J. Winkler, K. Schulz, S. Ulrich, J. Frahm, S. Kersten,
    J. Rehage, G. Breves, S. Häußler, H. Sauerwein, L. Locher, Archives of Animal
    Nutrition 68 (2014) 460–477.
  ufg: '<b>Dänicke, Sven u. a.</b>: Description of a bovine model for studying digestive
    and metabolic effects of a positive energy balance not biased by lactation or
    gravidity, in: <i>Archives of Animal Nutrition</i> 68 (2014), H. 6,  S. 460–477.'
  van: Dänicke S, Meyer U, Winkler J, Schulz K, Ulrich S, Frahm J, et al. Description
    of a bovine model for studying digestive and metabolic effects of a positive energy
    balance not biased by lactation or gravidity. Archives of Animal Nutrition. 2014;68(6):460–77.
date_created: 2025-06-15T10:36:14Z
date_updated: 2025-06-18T12:23:01Z
department:
- _id: DEP4010
doi: 10.1080/1745039x.2014.973243
extern: '1'
intvolume: '        68'
issue: '6'
keyword:
- blood chemistry
- dairy cows
- endotoxins
- energy balance
- energy content
- rumen fermentation
language:
- iso: eng
page: 460-477
place: Abingdon
publication: Archives of Animal Nutrition
publication_identifier:
  eissn:
  - 1477-2817
  issn:
  - 1745-039X
  - 0003-942X
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
status: public
title: Description of a bovine model for studying digestive and metabolic effects
  of a positive energy balance not biased by lactation or gravidity
type: scientific_journal_article
user_id: '83781'
volume: 68
year: '2014'
...