---
_id: '9697'
abstract:
- lang: eng
  text: Continuous processes offer more environmentally friendlier beer production
    compared to the batch production. However, the continuous production of mashing
    has not become state-of-the-art in the brewing industry. The controllability and
    flexibility of this process still has hurdles for practical implementation, but
    which are necessary to react to changing raw materials. Once overcome, a continuous
    mashing can be efficiently adapted to the raw materials. Both mean residence time
    and temperature were investigated as key parameters to influence the extract and
    fermentable sugar content of the wort. The continuous mashing process was implemented
    as continuous stirred tank reactor (CSTR) cascade consisting of mashing in (20°C),
    protein rest (50°C), β-amylase rest (62-64°C), saccharification rest (72°C) and
    mashing out (78°C). Two different temperature settings for the β-amylase rest
    were investigated with particular emphasis on fermentable sugars. Analysis of
    Variance (ANOVA) and a post-hoc analysis showed that the mean residence time and
    temperature settings were suitable control parameters for the fermentable sugars.
    In the experimental conditions, the most pronounced effect was with the β-amylase
    rest. These results broaden the understanding of heterogenous CSTR mashing systems
    about assembly and selection of process parameters
author:
- first_name: Patrick
  full_name: Wefing, Patrick
  id: '68976'
  last_name: Wefing
- first_name: Marc
  full_name: Trilling, Marc
  id: '81622'
  last_name: Trilling
  orcid: 0000-0002-3685-6383
- first_name: Arthur
  full_name: Gossen, Arthur
  id: '76446'
  last_name: Gossen
- first_name: Peter
  full_name: Neubauer, Peter
  last_name: Neubauer
- first_name: Jan
  full_name: Schneider, Jan
  id: '13209'
  last_name: Schneider
  orcid: 0000-0001-6401-8873
citation:
  ama: Wefing P, Trilling M, Gossen A, Neubauer P, Schneider J. A continuous mashing
    plant controlled by mean residence time. <i>Journal of The Institute of Brewing</i>.
    2023;129(1):1-23. doi:<a href="https://doi.org/10.58430/jib.v129i1.7">10.58430/jib.v129i1.7</a>
  apa: Wefing, P., Trilling, M., Gossen, A., Neubauer, P., &#38; Schneider, J. (2023).
    A continuous mashing plant controlled by mean residence time. <i>Journal of The
    Institute of Brewing</i>, <i>129</i>(1), 1–23. <a href="https://doi.org/10.58430/jib.v129i1.7">https://doi.org/10.58430/jib.v129i1.7</a>
  bjps: <b>Wefing P <i>et al.</i></b> (2023) A Continuous Mashing Plant Controlled
    by Mean Residence Time. <i>Journal of The Institute of Brewing</i> <b>129</b>,
    1–23.
  chicago: 'Wefing, Patrick, Marc Trilling, Arthur Gossen, Peter Neubauer, and Jan
    Schneider. “A Continuous Mashing Plant Controlled by Mean Residence Time.” <i>Journal
    of The Institute of Brewing</i> 129, no. 1 (2023): 1–23. <a href="https://doi.org/10.58430/jib.v129i1.7">https://doi.org/10.58430/jib.v129i1.7</a>.'
  chicago-de: 'Wefing, Patrick, Marc Trilling, Arthur Gossen, Peter Neubauer und Jan
    Schneider. 2023. A continuous mashing plant controlled by mean residence time.
    <i>Journal of The Institute of Brewing</i> 129, Nr. 1: 1–23. doi:<a href="https://doi.org/10.58430/jib.v129i1.7">10.58430/jib.v129i1.7</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Wefing, Patrick</span> ; <span
    style="font-variant:small-caps;">Trilling, Marc</span> ; <span style="font-variant:small-caps;">Gossen,
    Arthur</span> ; <span style="font-variant:small-caps;">Neubauer, Peter</span>
    ; <span style="font-variant:small-caps;">Schneider, Jan</span>: A continuous mashing
    plant controlled by mean residence time. In: <i>Journal of The Institute of Brewing</i>
    Bd. 129, Wiley (2023), Nr. 1, S. 1–23'
  havard: P. Wefing, M. Trilling, A. Gossen, P. Neubauer, J. Schneider, A continuous
    mashing plant controlled by mean residence time, Journal of The Institute of Brewing.
    129 (2023) 1–23.
  ieee: 'P. Wefing, M. Trilling, A. Gossen, P. Neubauer, and J. Schneider, “A continuous
    mashing plant controlled by mean residence time,” <i>Journal of The Institute
    of Brewing</i>, vol. 129, no. 1, pp. 1–23, 2023, doi: <a href="https://doi.org/10.58430/jib.v129i1.7">10.58430/jib.v129i1.7</a>.'
  mla: Wefing, Patrick, et al. “A Continuous Mashing Plant Controlled by Mean Residence
    Time.” <i>Journal of The Institute of Brewing</i>, vol. 129, no. 1, 2023, pp.
    1–23, <a href="https://doi.org/10.58430/jib.v129i1.7">https://doi.org/10.58430/jib.v129i1.7</a>.
  short: P. Wefing, M. Trilling, A. Gossen, P. Neubauer, J. Schneider, Journal of
    The Institute of Brewing 129 (2023) 1–23.
  ufg: '<b>Wefing, Patrick u. a.</b>: A continuous mashing plant controlled by mean
    residence time, in: <i>Journal of The Institute of Brewing</i> 129 (2023), H.
    1,  S. 1–23.'
  van: Wefing P, Trilling M, Gossen A, Neubauer P, Schneider J. A continuous mashing
    plant controlled by mean residence time. Journal of The Institute of Brewing.
    2023;129(1):1–23.
date_created: 2023-04-12T07:26:12Z
date_updated: 2025-01-30T15:33:02Z
ddc:
- '600'
department:
- _id: DEP4018
- _id: DEP1308
- _id: DEP4028
doi: 10.58430/jib.v129i1.7
has_accepted_license: '1'
intvolume: '       129'
issue: '1'
keyword:
- ontinuous mashing
- continuous stirred tank reactor
- mean residence time
- fermentable sugar
language:
- iso: eng
main_file_link:
- open_access: '1'
oa: '1'
page: 1-23
publication: Journal of The Institute of Brewing
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: A continuous mashing plant controlled by mean residence time
type: scientific_journal_article
user_id: '83781'
volume: 129
year: '2023'
...
---
_id: '6689'
abstract:
- lang: eng
  text: "Free amino nitrogen (FAN) concentrations in beer mash can be determined with
    machine learning algorithms\r\nfrom near-infrared (NIR) spectra. NIR spectroscopy
    is an alternative to a classical chemical analysis and\r\nallows for the application
    of inline process quality control. This study investigates the capabilities of\r\ndifferent
    machine learning techniques such as Ordinary Least Squares (OLS) regression, Decision
    Tree\r\nRegressor (DTR), Bayesian Ridge Regression (BRR), Ridge Regression (RR),
    K-nearest neighbours (KNN)\r\nregression as well as Support Vector Regression
    (SVR) to predict the FAN content in beer mash from NIR\r\nspectra. Various pre-processing
    strategies such as principal component analysis (PCA) and data\r\nstandardization
    were used to process NIR data that were used to train the machine learning algorithms.\r\nAlgorithm
    training was conducted with NIR data obtained from 16 beer mashes with varying
    FAN\r\nconcentrations. The trained models were then validated with 4 beer mashes
    that were not used for model\r\ntraining. Machine learning algorithms based on
    linear regression showed the highest prediction accuracy on\r\nunpre-processed
    data. BRR reached a root mean square error of calibration (RMSEC) of 2.58 mg/L
    (R2 = 0.96)\r\nand a prediction accuracy (RMSEP) of 2.81 mg/L (R2 = 0.96). The
    FAN concentration range of the investigated\r\nsamples was between approx. 180
    and 220 mg/L. Machine learning based NIR spectra analysis is an alternative\r\nto
    classical chemical FAN level determination methods and can also be used as inline
    sensor system."
article_type: original
author:
- first_name: Patrick
  full_name: Wefing, Patrick
  id: '68976'
  last_name: Wefing
- first_name: Florian
  full_name: Conradi, Florian
  id: '68967'
  last_name: Conradi
- first_name: Johannes
  full_name: Rämisch, Johannes
  last_name: Rämisch
- first_name: Peter
  full_name: Neubauer, Peter
  last_name: Neubauer
- first_name: Jan
  full_name: Schneider, Jan
  id: '13209'
  last_name: Schneider
  orcid: 0000-0001-6401-8873
citation:
  ama: Wefing P, Conradi F, Rämisch J, Neubauer P, Schneider J. Determination of free
    amino nitrogen in beer mash with an inline NIR transflectance probe and data evaluation
    by machine learning algorithms. <i>Brewing science </i>. 2021;74(9/10):107-121.
    doi:<a href="https://doi.org/10.23763/BrSc21-10wefing">https://doi.org/10.23763/BrSc21-10wefing</a>
  apa: Wefing, P., Conradi, F., Rämisch, J., Neubauer, P., &#38; Schneider, J. (2021).
    Determination of free amino nitrogen in beer mash with an inline NIR transflectance
    probe and data evaluation by machine learning algorithms. <i>Brewing Science </i>,
    <i>74</i>(9/10), 107–121. <a href="https://doi.org/10.23763/BrSc21-10wefing">https://doi.org/10.23763/BrSc21-10wefing</a>
  bjps: <b>Wefing P <i>et al.</i></b> (2021) Determination of Free Amino Nitrogen
    in Beer Mash with an Inline NIR Transflectance Probe and Data Evaluation by Machine
    Learning Algorithms. <i>Brewing science </i> <b>74</b>, 107–121.
  chicago: 'Wefing, Patrick, Florian Conradi, Johannes Rämisch, Peter Neubauer, and
    Jan Schneider. “Determination of Free Amino Nitrogen in Beer Mash with an Inline
    NIR Transflectance Probe and Data Evaluation by Machine Learning Algorithms.”
    <i>Brewing Science </i> 74, no. 9/10 (2021): 107–21. <a href="https://doi.org/10.23763/BrSc21-10wefing">https://doi.org/10.23763/BrSc21-10wefing</a>.'
  chicago-de: 'Wefing, Patrick, Florian Conradi, Johannes Rämisch, Peter Neubauer
    und Jan Schneider. 2021. Determination of free amino nitrogen in beer mash with
    an inline NIR transflectance probe and data evaluation by machine learning algorithms.
    <i>Brewing science </i> 74, Nr. 9/10: 107–121. doi:<a href="https://doi.org/10.23763/BrSc21-10wefing">https://doi.org/10.23763/BrSc21-10wefing</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Wefing, Patrick</span> ; <span
    style="font-variant:small-caps;">Conradi, Florian</span> ; <span style="font-variant:small-caps;">Rämisch,
    Johannes</span> ; <span style="font-variant:small-caps;">Neubauer, Peter</span>
    ; <span style="font-variant:small-caps;">Schneider, Jan</span>: Determination
    of free amino nitrogen in beer mash with an inline NIR transflectance probe and
    data evaluation by machine learning algorithms. In: <i>Brewing science </i> Bd.
    74, Carl (2021), Nr. 9/10, S. 107–121'
  havard: P. Wefing, F. Conradi, J. Rämisch, P. Neubauer, J. Schneider, Determination
    of free amino nitrogen in beer mash with an inline NIR transflectance probe and
    data evaluation by machine learning algorithms, Brewing Science . 74 (2021) 107–121.
  ieee: 'P. Wefing, F. Conradi, J. Rämisch, P. Neubauer, and J. Schneider, “Determination
    of free amino nitrogen in beer mash with an inline NIR transflectance probe and
    data evaluation by machine learning algorithms,” <i>Brewing science </i>, vol.
    74, no. 9/10, pp. 107–121, 2021, doi: <a href="https://doi.org/10.23763/BrSc21-10wefing">https://doi.org/10.23763/BrSc21-10wefing</a>.'
  mla: Wefing, Patrick, et al. “Determination of Free Amino Nitrogen in Beer Mash
    with an Inline NIR Transflectance Probe and Data Evaluation by Machine Learning
    Algorithms.” <i>Brewing Science </i>, vol. 74, no. 9/10, 2021, pp. 107–21, <a
    href="https://doi.org/10.23763/BrSc21-10wefing">https://doi.org/10.23763/BrSc21-10wefing</a>.
  short: P. Wefing, F. Conradi, J. Rämisch, P. Neubauer, J. Schneider, Brewing Science  74
    (2021) 107–121.
  ufg: '<b>Wefing, Patrick u. a.</b>: Determination of free amino nitrogen in beer
    mash with an inline NIR transflectance probe and data evaluation by machine learning
    algorithms, in: <i>Brewing science </i> 74 (2021), H. 9/10,  S. 107–121.'
  van: Wefing P, Conradi F, Rämisch J, Neubauer P, Schneider J. Determination of free
    amino nitrogen in beer mash with an inline NIR transflectance probe and data evaluation
    by machine learning algorithms. Brewing science . 2021;74(9/10):107–21.
date_created: 2021-11-02T10:06:04Z
date_updated: 2025-01-30T15:43:53Z
department:
- _id: DEP1308
- _id: DEP4028
doi: https://doi.org/10.23763/BrSc21-10wefing
intvolume: '        74'
issue: 9/10
keyword:
- mashing
- NIR
- machine learning
- FAN
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.researchgate.net/publication/355735532_Determination_of_free_amino_nitrogen_in_beer_mash_with_an_inline_NIR_transflectance_probe_and_data_evaluation_by_machine_learning_algorithms
oa: '1'
page: 107 - 121
publication: 'Brewing science '
publication_identifier:
  eissn:
  - 0723-1520
  issn:
  - 1866-5195
publication_status: published
publisher: Carl
quality_controlled: '1'
status: public
title: Determination of free amino nitrogen in beer mash with an inline NIR transflectance
  probe and data evaluation by machine learning algorithms
type: journal_article
user_id: '83781'
volume: 74
year: '2021'
...
---
_id: '5419'
abstract:
- lang: eng
  text: Continuous mashing provides advantages compared to conventional batch-wise
    mashing in terms of space time yield. The majority of fermentable sugars are generated
    during the so-called “β-amylase rest” (62–64 ◦C). These low molecular sugars are
    fermented later in the brewing process by yeasts and therefore determine the beer
    attenuation degree. Biological malt variations complicate the application of a
    continuous system in industrial scale particularly concerning targeted quality
    parameters. The aim is the prediction of sugar formation from process parameters
    for a real time control system. Therefore, a semi-empirical model for sugar formation
    in a continuous stirred tank reactor (CSTR) system was developed under incorporation
    of the residence time distri- bution (RTD). The here presented model, which focuses
    on the “β-amylase rest”, is able to predict fermentable sugar concentrations in
    the continuous “β-amylase rest” with sufficient accuracy, in contrast to models
    that only use the flow rate and the reactor volume to determine the reaction time.
    However, the precision and trueness depend on the quality of the empirical data
    acquired previously in laboratory experiments for the selected temperature and
    raw material quality.
article_number: '107765'
article_type: original
author:
- first_name: Patrick
  full_name: Wefing, Patrick
  id: '68976'
  last_name: Wefing
- first_name: Florian
  full_name: Conradi, Florian
  id: '68967'
  last_name: Conradi
- first_name: Marc
  full_name: Trilling-Haasler, Marc
  id: '81622'
  last_name: Trilling-Haasler
  orcid: 0000-0002-3685-6383
- first_name: Peter
  full_name: Neubauer, Peter
  last_name: Neubauer
- first_name: Jan
  full_name: Schneider, Jan
  id: '13209'
  last_name: Schneider
  orcid: 0000-0001-6401-8873
citation:
  ama: Wefing P, Conradi F, Trilling-Haasler M, Neubauer P, Schneider J. Approach
    for modelling the extract formation in continuous conducted “beta-amylase rest”
    as part of the production of beer mash with targeted sugar content. <i>Biochemical
    Engineering Journal </i>. 2020;164. doi:<a href="https://doi.org/10.1016/j.bej.2020.107765">10.1016/j.bej.2020.107765</a>
  apa: Wefing, P., Conradi, F., Trilling-Haasler, M., Neubauer, P., &#38; Schneider,
    J. (2020). Approach for modelling the extract formation in continuous conducted
    “beta-amylase rest” as part of the production of beer mash with targeted sugar
    content. <i>Biochemical Engineering Journal </i>, <i>164</i>, Article 107765.
    <a href="https://doi.org/10.1016/j.bej.2020.107765">https://doi.org/10.1016/j.bej.2020.107765</a>
  bjps: <b>Wefing P <i>et al.</i></b> (2020) Approach for Modelling the Extract Formation
    in Continuous Conducted ‘Beta-Amylase Rest’ as Part of the Production of Beer
    Mash with Targeted Sugar Content. <i>Biochemical Engineering Journal </i> <b>164</b>.
  chicago: Wefing, Patrick, Florian Conradi, Marc Trilling-Haasler, Peter Neubauer,
    and Jan Schneider. “Approach for Modelling the Extract Formation in Continuous
    Conducted ‘Beta-Amylase Rest’ as Part of the Production of Beer Mash with Targeted
    Sugar Content.” <i>Biochemical Engineering Journal </i> 164 (2020). <a href="https://doi.org/10.1016/j.bej.2020.107765">https://doi.org/10.1016/j.bej.2020.107765</a>.
  chicago-de: Wefing, Patrick, Florian Conradi, Marc Trilling-Haasler, Peter Neubauer
    und Jan Schneider. 2020. Approach for modelling the extract formation in continuous
    conducted „beta-amylase rest“ as part of the production of beer mash with targeted
    sugar content. <i>Biochemical Engineering Journal </i> 164. doi:<a href="https://doi.org/10.1016/j.bej.2020.107765">10.1016/j.bej.2020.107765</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Wefing, Patrick</span> ; <span
    style="font-variant:small-caps;">Conradi, Florian</span> ; <span style="font-variant:small-caps;">Trilling-Haasler,
    Marc</span> ; <span style="font-variant:small-caps;">Neubauer, Peter</span> ;
    <span style="font-variant:small-caps;">Schneider, Jan</span>: Approach for modelling
    the extract formation in continuous conducted „beta-amylase rest“ as part of the
    production of beer mash with targeted sugar content. In: <i>Biochemical Engineering
    Journal </i> Bd. 164 (2020)'
  havard: P. Wefing, F. Conradi, M. Trilling-Haasler, P. Neubauer, J. Schneider, Approach
    for modelling the extract formation in continuous conducted “beta-amylase rest”
    as part of the production of beer mash with targeted sugar content, Biochemical
    Engineering Journal . 164 (2020).
  ieee: 'P. Wefing, F. Conradi, M. Trilling-Haasler, P. Neubauer, and J. Schneider,
    “Approach for modelling the extract formation in continuous conducted ‘beta-amylase
    rest’ as part of the production of beer mash with targeted sugar content,” <i>Biochemical
    Engineering Journal </i>, vol. 164, Art. no. 107765, 2020, doi: <a href="https://doi.org/10.1016/j.bej.2020.107765">10.1016/j.bej.2020.107765</a>.'
  mla: Wefing, Patrick, et al. “Approach for Modelling the Extract Formation in Continuous
    Conducted ‘Beta-Amylase Rest’ as Part of the Production of Beer Mash with Targeted
    Sugar Content.” <i>Biochemical Engineering Journal </i>, vol. 164, 107765, 2020,
    <a href="https://doi.org/10.1016/j.bej.2020.107765">https://doi.org/10.1016/j.bej.2020.107765</a>.
  short: P. Wefing, F. Conradi, M. Trilling-Haasler, P. Neubauer, J. Schneider, Biochemical
    Engineering Journal  164 (2020).
  ufg: '<b>Wefing, Patrick u. a.</b>: Approach for modelling the extract formation
    in continuous conducted „beta-amylase rest“ as part of the production of beer
    mash with targeted sugar content, in: <i>Biochemical Engineering Journal </i>
    164 (2020).'
  van: Wefing P, Conradi F, Trilling-Haasler M, Neubauer P, Schneider J. Approach
    for modelling the extract formation in continuous conducted “beta-amylase rest”
    as part of the production of beer mash with targeted sugar content. Biochemical
    Engineering Journal . 2020;164.
date_created: 2021-04-08T05:59:08Z
date_updated: 2024-07-03T07:08:55Z
department:
- _id: DEP4023
- _id: DEP1308
- _id: DEP4018
doi: 10.1016/j.bej.2020.107765
intvolume: '       164'
keyword:
- Continuous mashing
- Residence time distribution
- Beer
- Enzyme bioreactor
- Maltose rest
language:
- iso: eng
publication: 'Biochemical Engineering Journal '
publication_status: published
quality_controlled: '1'
status: public
title: Approach for modelling the extract formation in continuous conducted "beta-amylase
  rest" as part of the production of beer mash with targeted sugar content
type: journal_article
user_id: '83780'
volume: 164
year: '2020'
...
