---
_id: '5406'
abstract:
- lang: eng
  text: "\r\nThe pentacyclic triterpenes oleanolic acid (OA) and ursolic acid (UA)
    in Salvia triloba are attractive ingredients for cosmetic and pharmaceutical formulations.
    These triterpenoids are constitution isomers and differ only in the position of
    one methyl group in their chemical structures. Therefore it is difficult to achieve
    a baseline separation by standard RP-HPLC systems. Another challenge is that the
    complex plant contains a large variety of similar compounds. To achieve precise
    results for the target molecules, these compounds should be removed prior to analysis.
    Due to the large application of these two triterpenes, a fast quantification method
    is favored. If the triterpenes are extracted with aqueous two-phase systems, the
    target substances are enriched in a surfactant-rich phase. For this application,
    it is desirable to develop a method that is capable of quantifying both triterpenes
    directly by RP-HPLC without additional purification steps.\r\n\r\nThe optimal
    chromatographic conditions for pure substances as well as for crude surfactant-containing
    extracts were accomplished on a Nucleodur C18 ISIS column by isocratic elution
    with methanol/water/acetic acid/triethanolamine (90:10:0.04:0.02 v/v) as the mobile
    phase and a column temperature of 10°C. The flow rate was 0.6 mL/min, and the
    detection wavelength was 210 nm. With these parameters, a baseline separation
    was achieved and the calibration curve showed a very good linearity (R2 > 0.999
    for OA and UA) within the test range. The method is simple, rapid, and reliable
    for the quantification of crude extracts from plant material.\r\n"
author:
- first_name: Pia
  full_name: Schneider, Pia
  id: '75629'
  last_name: Schneider
- first_name: S. S.
  full_name: Hosseiny, S. S.
  last_name: Hosseiny
- first_name: F.
  full_name: Bischoff, F.
  last_name: Bischoff
- first_name: Ulrich
  full_name: Müller, Ulrich
  id: '12119'
  last_name: Müller
- first_name: H. J.
  full_name: Bart, H. J.
  last_name: Bart
- first_name: K.
  full_name: Schlitter, K.
  last_name: Schlitter
- first_name: V.
  full_name: Jordan, V.
  last_name: Jordan
citation:
  ama: Schneider P, Hosseiny SS, Bischoff F, et al. SURFACTANT MEDIATED EXTRACTION
    OF TRITERPENES AND THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM. <i>Instrumentation
    Science &#38; Technology</i>. 2011:407-418. doi:<a href="https://doi.org/10.1080/10739149.2011.602167">10.1080/10739149.2011.602167</a>
  apa: Schneider, P., Hosseiny, S. S., Bischoff, F., Müller, U., Bart, H. J., Schlitter,
    K., &#38; Jordan, V. (2011). SURFACTANT MEDIATED EXTRACTION OF TRITERPENES AND
    THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM. <i>Instrumentation Science
    &#38; Technology</i>, 407–418. <a href="https://doi.org/10.1080/10739149.2011.602167">https://doi.org/10.1080/10739149.2011.602167</a>
  bjps: <b>Schneider P <i>et al.</i></b> (2011) SURFACTANT MEDIATED EXTRACTION OF
    TRITERPENES AND THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM. <i>Instrumentation
    Science &#38; Technology</i> 407–418.
  chicago: Schneider, Pia, S. S. Hosseiny, F. Bischoff, Ulrich Müller, H. J. Bart,
    K. Schlitter, and V. Jordan. “SURFACTANT MEDIATED EXTRACTION OF TRITERPENES AND
    THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM.” <i>Instrumentation Science
    &#38; Technology</i>, 2011, 407–18. <a href="https://doi.org/10.1080/10739149.2011.602167">https://doi.org/10.1080/10739149.2011.602167</a>.
  chicago-de: 'Schneider, Pia, S. S. Hosseiny, F. Bischoff, Ulrich Müller, H. J. Bart,
    K. Schlitter und V. Jordan. 2011. SURFACTANT MEDIATED EXTRACTION OF TRITERPENES
    AND THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM. <i>Instrumentation Science
    &#38; Technology</i>: 407–418. doi:<a href="https://doi.org/10.1080/10739149.2011.602167,">10.1080/10739149.2011.602167,</a>
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Schneider, Pia</span> ; <span
    style="font-variant:small-caps;">Hosseiny, S. S.</span> ; <span style="font-variant:small-caps;">Bischoff,
    F.</span> ; <span style="font-variant:small-caps;">Müller, Ulrich</span> ; <span
    style="font-variant:small-caps;">Bart, H. J.</span> ; <span style="font-variant:small-caps;">Schlitter,
    K.</span> ; <span style="font-variant:small-caps;">Jordan, V.</span>: SURFACTANT
    MEDIATED EXTRACTION OF TRITERPENES AND THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR
    SYSTEM. In: <i>Instrumentation Science &#38; Technology</i> (2011), S. 407–418'
  havard: P. Schneider, S.S. Hosseiny, F. Bischoff, U. Müller, H.J. Bart, K. Schlitter,
    V. Jordan, SURFACTANT MEDIATED EXTRACTION OF TRITERPENES AND THEIR DIRECT HPLC
    ANALYSIS FROM THE MICELLAR SYSTEM, Instrumentation Science &#38; Technology. (2011)
    407–418.
  ieee: P. Schneider <i>et al.</i>, “SURFACTANT MEDIATED EXTRACTION OF TRITERPENES
    AND THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM,” <i>Instrumentation Science
    &#38; Technology</i>, pp. 407–418, 2011.
  mla: Schneider, Pia, et al. “SURFACTANT MEDIATED EXTRACTION OF TRITERPENES AND THEIR
    DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM.” <i>Instrumentation Science &#38;
    Technology</i>, 2011, pp. 407–18, doi:<a href="https://doi.org/10.1080/10739149.2011.602167">10.1080/10739149.2011.602167</a>.
  short: P. Schneider, S.S. Hosseiny, F. Bischoff, U. Müller, H.J. Bart, K. Schlitter,
    V. Jordan, Instrumentation Science &#38; Technology (2011) 407–418.
  ufg: '<b>Schneider, Pia et. al. (2011)</b>: SURFACTANT MEDIATED EXTRACTION OF TRITERPENES
    AND THEIR DIRECT HPLC ANALYSIS FROM THE MICELLAR SYSTEM, in: <i>Instrumentation
    Science &#38; Technology</i>, S. 407–418.'
  van: Schneider P, Hosseiny SS, Bischoff F, Müller U, Bart HJ, Schlitter K, et al.
    SURFACTANT MEDIATED EXTRACTION OF TRITERPENES AND THEIR DIRECT HPLC ANALYSIS FROM
    THE MICELLAR SYSTEM. Instrumentation Science &#38; Technology. 2011;407–18.
date_created: 2021-04-07T12:32:48Z
date_updated: 2023-03-15T13:49:59Z
department:
- _id: DEP4023
- _id: DEP4009
doi: 10.1080/10739149.2011.602167
keyword:
- oleanolic acid
- Salvia triloba
- surfactants
- triterpenes
- ursolic acid
language:
- iso: eng
page: 407-418
publication: Instrumentation Science & Technology
publication_identifier:
  eissn:
  - 1525-6030
  issn:
  - 1073-9149
publication_status: published
status: public
title: SURFACTANT MEDIATED EXTRACTION OF TRITERPENES AND THEIR DIRECT HPLC ANALYSIS
  FROM THE MICELLAR SYSTEM
type: journal_article
user_id: '15514'
year: 2011
...