---
_id: '13338'
abstract:
- lang: eng
  text: This work discusses the additive manufacturing of an axicon lens using cyclic
    olefin copolymer (TOPAS), and its characterization between 100 GHz and 300 GHz.
    The proposed manufacturing process followed by dip-coating post-processing provides
    an improved surface finish. Additionally, the terahertz output of the lens remains
    intact over the entire frequency range.
author:
- first_name: Abhijeet Narendra
  full_name: Shrotri, Abhijeet Narendra
  id: '74090'
  last_name: Shrotri
  orcid: 0000-0003-2116-156X
- first_name: Suraj
  full_name: Joshi, Suraj
  last_name: Joshi
- first_name: Lea
  full_name: Vogel, Lea
  id: '77129'
  last_name: Vogel
- first_name: Annamarija
  full_name: Starsaja, Annamarija
  last_name: Starsaja
- first_name: Oliver
  full_name: Stübbe, Oliver
  id: '51864'
  last_name: Stübbe
  orcid: 0000-0001-7293-6893
- first_name: Sascha
  full_name: Preu, Sascha
  last_name: Preu
citation:
  ama: Shrotri AN, Joshi S, Vogel L, Starsaja A, Stübbe O, Preu S. <i>Terahertz Axicon
    Lenses</i>. IEEE; 2026:2. doi:<a href="https://doi.org/10.1109/irmmw-thz61557.2025.11319870">10.1109/irmmw-thz61557.2025.11319870</a>
  apa: Shrotri, A. N., Joshi, S., Vogel, L., Starsaja, A., Stübbe, O., &#38; Preu,
    S. (2026). Terahertz Axicon Lenses. In <i>2025 50th International Conference on
    Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)</i> (p. 2). IEEE. <a href="https://doi.org/10.1109/irmmw-thz61557.2025.11319870">https://doi.org/10.1109/irmmw-thz61557.2025.11319870</a>
  bjps: '<b>Shrotri AN <i>et al.</i></b> (2026) <i>Terahertz Axicon Lenses</i>. Piscataway,
    NJ: IEEE.'
  chicago: 'Shrotri, Abhijeet Narendra, Suraj Joshi, Lea Vogel, Annamarija Starsaja,
    Oliver Stübbe, and Sascha Preu. <i>Terahertz Axicon Lenses</i>. <i>2025 50th International
    Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)</i>. Piscataway,
    NJ: IEEE, 2026. <a href="https://doi.org/10.1109/irmmw-thz61557.2025.11319870">https://doi.org/10.1109/irmmw-thz61557.2025.11319870</a>.'
  chicago-de: 'Shrotri, Abhijeet Narendra, Suraj Joshi, Lea Vogel, Annamarija Starsaja,
    Oliver Stübbe und Sascha Preu. 2026. <i>Terahertz Axicon Lenses</i>. <i>2025 50th
    International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)</i>.
    Piscataway, NJ: IEEE. doi:<a href="https://doi.org/10.1109/irmmw-thz61557.2025.11319870">10.1109/irmmw-thz61557.2025.11319870</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Shrotri, Abhijeet Narendra</span>
    ; <span style="font-variant:small-caps;">Joshi, Suraj</span> ; <span style="font-variant:small-caps;">Vogel,
    Lea</span> ; <span style="font-variant:small-caps;">Starsaja, Annamarija</span>
    ; <span style="font-variant:small-caps;">Stübbe, Oliver</span> ; <span style="font-variant:small-caps;">Preu,
    Sascha</span>: <i>Terahertz Axicon Lenses</i>. Piscataway, NJ : IEEE, 2026'
  havard: A.N. Shrotri, S. Joshi, L. Vogel, A. Starsaja, O. Stübbe, S. Preu, Terahertz
    Axicon Lenses, IEEE, Piscataway, NJ, 2026.
  ieee: 'A. N. Shrotri, S. Joshi, L. Vogel, A. Starsaja, O. Stübbe, and S. Preu, <i>Terahertz
    Axicon Lenses</i>. Piscataway, NJ: IEEE, 2026, p. 2. doi: <a href="https://doi.org/10.1109/irmmw-thz61557.2025.11319870">10.1109/irmmw-thz61557.2025.11319870</a>.'
  mla: Shrotri, Abhijeet Narendra, et al. “Terahertz Axicon Lenses.” <i>2025 50th
    International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)</i>,
    IEEE, 2026, p. 2, <a href="https://doi.org/10.1109/irmmw-thz61557.2025.11319870">https://doi.org/10.1109/irmmw-thz61557.2025.11319870</a>.
  short: A.N. Shrotri, S. Joshi, L. Vogel, A. Starsaja, O. Stübbe, S. Preu, Terahertz
    Axicon Lenses, IEEE, Piscataway, NJ, 2026.
  ufg: '<b>Shrotri, Abhijeet Narendra u. a.</b>: Terahertz Axicon Lenses, Piscataway,
    NJ 2026.'
  van: 'Shrotri AN, Joshi S, Vogel L, Starsaja A, Stübbe O, Preu S. Terahertz Axicon
    Lenses. 2025 50th International Conference on Infrared, Millimeter, and Terahertz
    Waves (IRMMW-THz). Piscataway, NJ: IEEE; 2026.'
conference:
  end_date: 2025-08-22
  location: ' Helsinki, Finland '
  name: 50th International Conference on Infrared, Millimeter, and Terahertz Waves
    (IRMMW-THz)
  start_date: 2025-08-17
date_created: 2026-01-16T14:48:22Z
date_updated: 2026-02-10T12:42:43Z
department:
- _id: DEP5020
- _id: DEP6020
doi: 10.1109/irmmw-thz61557.2025.11319870
keyword:
- Manufacturing processes
- Surface waves
- Three-dimensional printing
- Surface finishing
- Surface treatment
- Lenses
language:
- iso: eng
page: '2'
place: Piscataway, NJ
publication: 2025 50th International Conference on Infrared, Millimeter, and Terahertz
  Waves (IRMMW-THz)
publication_status: published
publisher: IEEE
status: public
title: Terahertz Axicon Lenses
type: conference_editor_article
user_id: '83781'
year: '2026'
...
---
_id: '11377'
abstract:
- lang: eng
  text: <jats:p>consuming and often performed rather empirically. Efficient optimization
    of multiple objectives such as process time, viable cell density, number of operating
    steps &amp; cultivation scales, required medium, amount of product as well as
    product quality depicts a promising approach. This contribution presents a workflow
    which couples uncertainty-based upstream simulation and Bayes optimization using
    Gaussian processes. Its application is demonstrated in a simulation case study
    for a relevant industrial task in process development, the design of a robust
    cell culture expansion process (seed train), meaning that despite uncertainties
    and variabilities concerning cell growth, low variations of viable cell density
    during the seed train are obtained. Compared to a non-optimized reference seed
    train, the optimized process showed much lower deviation rates regarding viable
    cell densities (&lt;10% instead of 41.7%) using five or four shake flask scales
    and seed train duration could be reduced by 56 h from 576 h to 520 h. Overall,
    it is shown that applying Bayes optimization allows for optimization of a multi-objective
    optimization function with several optimizable input variables and under a considerable
    amount of constraints with a low computational effort. This approach provides
    the potential to be used in the form of a decision tool, e.g., for the choice
    of an optimal and robust seed train design or for further optimization tasks within
    process development.
article_number: '883'
author:
- first_name: Tanja
  full_name: Hernández Rodriguez, Tanja
  id: '52466'
  last_name: Hernández Rodriguez
- first_name: Anton
  full_name: Sekulic, Anton
  last_name: Sekulic
- first_name: Markus
  full_name: Lange-Hegermann, Markus
  id: '71761'
  last_name: Lange-Hegermann
- first_name: Björn
  full_name: Frahm, Björn
  id: '45666'
  last_name: Frahm
citation:
  ama: Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing Robust
    Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization
    Applied to a Biopharmaceutical Seed Train Design. <i>Processes</i>. 2022;10(5).
    doi:<a href="https://doi.org/10.3390/pr10050883">10.3390/pr10050883</a>
  apa: Hernández Rodriguez, T., Sekulic, A., Lange-Hegermann, M., &#38; Frahm, B.
    (2022). Designing Robust Biotechnological Processes Regarding Variabilities Using
    Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.
    <i>Processes</i>, <i>10</i>(5), Article 883. <a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>
  bjps: <b>Hernández Rodriguez T <i>et al.</i></b> (2022) Designing Robust Biotechnological
    Processes Regarding Variabilities Using Multi-Objective Optimization Applied to
    a Biopharmaceutical Seed Train Design. <i>Processes</i> <b>10</b>.
  chicago: Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann, and
    Björn Frahm. “Designing Robust Biotechnological Processes Regarding Variabilities
    Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.”
    <i>Processes</i> 10, no. 5 (2022). <a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>.
  chicago-de: Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann und
    Björn Frahm. 2022. Designing Robust Biotechnological Processes Regarding Variabilities
    Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.
    <i>Processes</i> 10, Nr. 5. doi:<a href="https://doi.org/10.3390/pr10050883">10.3390/pr10050883</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Hernández Rodriguez, Tanja</span>
    ; <span style="font-variant:small-caps;">Sekulic, Anton</span> ; <span style="font-variant:small-caps;">Lange-Hegermann,
    Markus</span> ; <span style="font-variant:small-caps;">Frahm, Björn</span>: Designing
    Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective
    Optimization Applied to a Biopharmaceutical Seed Train Design. In: <i>Processes</i>
    Bd. 10. Basel, MDPI AG (2022), Nr. 5'
  havard: T. Hernández Rodriguez, A. Sekulic, M. Lange-Hegermann, B. Frahm, Designing
    Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective
    Optimization Applied to a Biopharmaceutical Seed Train Design, Processes. 10 (2022).
  ieee: 'T. Hernández Rodriguez, A. Sekulic, M. Lange-Hegermann, and B. Frahm, “Designing
    Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective
    Optimization Applied to a Biopharmaceutical Seed Train Design,” <i>Processes</i>,
    vol. 10, no. 5, Art. no. 883, 2022, doi: <a href="https://doi.org/10.3390/pr10050883">10.3390/pr10050883</a>.'
  mla: Hernández Rodriguez, Tanja, et al. “Designing Robust Biotechnological Processes
    Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical
    Seed Train Design.” <i>Processes</i>, vol. 10, no. 5, 883, 2022, <a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>.
  short: T. Hernández Rodriguez, A. Sekulic, M. Lange-Hegermann, B. Frahm, Processes
    10 (2022).
  ufg: '<b>Hernández Rodriguez, Tanja u. a.</b>: Designing Robust Biotechnological
    Processes Regarding Variabilities Using Multi-Objective Optimization Applied to
    a Biopharmaceutical Seed Train Design, in: <i>Processes</i> 10 (2022), H. 5.'
  van: Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing Robust
    Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization
    Applied to a Biopharmaceutical Seed Train Design. Processes. 2022;10(5).
date_created: 2024-04-25T13:35:04Z
date_updated: 2024-05-21T09:30:15Z
department:
- _id: DEP4000
doi: 10.3390/pr10050883
intvolume: '        10'
issue: '5'
keyword:
- Gaussian processes
- Bayes optimization
- Pareto optimization
- multi-objective
- cell culture
- seed train
language:
- iso: eng
place: Basel
publication: Processes
publication_identifier:
  eissn:
  - 2227-9717
publication_status: published
publisher: MDPI AG
status: public
title: Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective
  Optimization Applied to a Biopharmaceutical Seed Train Design
type: scientific_journal_article
user_id: '83781'
volume: 10
year: '2022'
...
---
_id: '10193'
abstract:
- lang: eng
  text: Development and optimization of biopharmaceutical production processes with
    cell cultures is cost- and time-consuming and often performed rather empirically.
    Efficient optimization of multiple objectives such as process time, viable cell
    density, number of operating steps & cultivation scales, required medium, amount
    of product as well as product quality depicts a promising approach. This contribution
    presents a workflow which couples uncertainty-based upstream simulation and Bayes
    optimization using Gaussian processes. Its application is demonstrated in a simulation
    case study for a relevant industrial task in process development, the design of
    a robust cell culture expansion process (seed train), meaning that despite uncertainties
    and variabilities concerning cell growth, low variations of viable cell density
    during the seed train are obtained. Compared to a non-optimized reference seed
    train, the optimized process showed much lower deviation rates regarding viable
    cell densities (<10% instead of 41.7%) using five or four shake flask scales and
    seed train duration could be reduced by 56 h from 576 h to 520 h. Overall, it
    is shown that applying Bayes optimization allows for optimization of a multi-objective
    optimization function with several optimizable input variables and under a considerable
    amount of constraints with a low computational effort. This approach provides
    the potential to be used in the form of a decision tool, e.g., for the choice
    of an optimal and robust seed train design or for further optimization tasks within
    process development.
author:
- first_name: Tanja
  full_name: Hernández Rodriguez, Tanja
  id: '52466'
  last_name: Hernández Rodriguez
- first_name: Anton
  full_name: Sekulic, Anton
  last_name: Sekulic
- first_name: Markus
  full_name: Lange-Hegermann, Markus
  id: '71761'
  last_name: Lange-Hegermann
- first_name: Björn
  full_name: Frahm, Björn
  id: '45666'
  last_name: Frahm
citation:
  ama: 'Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing robust
    biotechnological processes regarding variabilities using multi-objective optimization
    applied to a biopharmaceutical seed train design. In: Pörtner R, Möller J, eds.
    <i>Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing</i>.
    Vol special issue. Processes : open access journal. MDPI; 2022:21-48. doi:<a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>'
  apa: 'Hernández Rodriguez, T., Sekulic, A., Lange-Hegermann, M., &#38; Frahm, B.
    (2022). Designing robust biotechnological processes regarding variabilities using
    multi-objective optimization applied to a biopharmaceutical seed train design.
    In R. Pörtner &#38; J. Möller (Eds.), <i>Bioprocess Systems Engineering Applications
    in Pharmaceutical Manufacturing: Vol. special issue</i> (pp. 21–48). MDPI. <a
    href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>'
  bjps: '<b>Hernández Rodriguez T <i>et al.</i></b> (2022) Designing Robust Biotechnological
    Processes Regarding Variabilities Using Multi-Objective Optimization Applied to
    a Biopharmaceutical Seed Train Design. In Pörtner R and Möller J (eds), <i>Bioprocess
    Systems Engineering Applications in Pharmaceutical Manufacturing</i>, vol. special
    issue. Basel: MDPI, pp. 21–48.'
  chicago: 'Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann, and
    Björn Frahm. “Designing Robust Biotechnological Processes Regarding Variabilities
    Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.”
    In <i>Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing</i>,
    edited by Ralf Pörtner and Johannes Möller, special issue:21–48. Processes : Open
    Access Journal. Basel: MDPI, 2022. <a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>.'
  chicago-de: 'Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann und
    Björn Frahm. 2022. Designing robust biotechnological processes regarding variabilities
    using multi-objective optimization applied to a biopharmaceutical seed train design.
    In: <i>Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing</i>,
    hg. von Ralf Pörtner und Johannes Möller, special issue:21–48. Processes : open
    access journal. Basel: MDPI. doi:<a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Hernández Rodriguez, Tanja</span>
    ; <span style="font-variant:small-caps;">Sekulic, Anton</span> ; <span style="font-variant:small-caps;">Lange-Hegermann,
    Markus</span> ; <span style="font-variant:small-caps;">Frahm, Björn</span>: Designing
    robust biotechnological processes regarding variabilities using multi-objective
    optimization applied to a biopharmaceutical seed train design. In: <span style="font-variant:small-caps;">Pörtner,
    R.</span> ; <span style="font-variant:small-caps;">Möller, J.</span> (Hrsg.):
    <i>Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing</i>,
    <i>Processes : open access journal</i>. Bd. special issue. Basel : MDPI, 2022,
    S. 21–48'
  havard: 'T. Hernández Rodriguez, A. Sekulic, M. Lange-Hegermann, B. Frahm, Designing
    robust biotechnological processes regarding variabilities using multi-objective
    optimization applied to a biopharmaceutical seed train design, in: R. Pörtner,
    J. Möller (Eds.), Bioprocess Systems Engineering Applications in Pharmaceutical
    Manufacturing, MDPI, Basel, 2022: pp. 21–48.'
  ieee: 'T. Hernández Rodriguez, A. Sekulic, M. Lange-Hegermann, and B. Frahm, “Designing
    robust biotechnological processes regarding variabilities using multi-objective
    optimization applied to a biopharmaceutical seed train design,” in <i>Bioprocess
    Systems Engineering Applications in Pharmaceutical Manufacturing</i>, vol. special
    issue, R. Pörtner and J. Möller, Eds. Basel: MDPI, 2022, pp. 21–48. doi: <a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>.'
  mla: Hernández Rodriguez, Tanja, et al. “Designing Robust Biotechnological Processes
    Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical
    Seed Train Design.” <i>Bioprocess Systems Engineering Applications in Pharmaceutical
    Manufacturing</i>, edited by Ralf Pörtner and Johannes Möller, vol. special issue,
    MDPI, 2022, pp. 21–48, <a href="https://doi.org/10.3390/pr10050883">https://doi.org/10.3390/pr10050883</a>.
  short: 'T. Hernández Rodriguez, A. Sekulic, M. Lange-Hegermann, B. Frahm, in: R.
    Pörtner, J. Möller (Eds.), Bioprocess Systems Engineering Applications in Pharmaceutical
    Manufacturing, MDPI, Basel, 2022, pp. 21–48.'
  ufg: '<b>Hernández Rodriguez, Tanja u. a.</b>: Designing robust biotechnological
    processes regarding variabilities using multi-objective optimization applied to
    a biopharmaceutical seed train design, in: <i>Pörtner, Ralf/Möller, Johannes (Hgg.)</i>:
    Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, Band
    <i>special issue</i>, Basel 2022 (Processes : open access journal),  S. 21–48.'
  van: 'Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing robust
    biotechnological processes regarding variabilities using multi-objective optimization
    applied to a biopharmaceutical seed train design. In: Pörtner R, Möller J, editors.
    Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing. Basel:
    MDPI; 2022. p. 21–48. (Processes : open access journal; vol. special issue).'
date_created: 2023-08-08T12:58:36Z
date_updated: 2023-08-16T09:24:16Z
department:
- _id: DEP4000
doi: https://doi.org/10.3390/pr10050883
editor:
- first_name: Ralf
  full_name: Pörtner, Ralf
  last_name: Pörtner
- first_name: Johannes
  full_name: Möller, Johannes
  last_name: Möller
keyword:
- Gaussian processes
- Bayes optimization
- Pareto optimization
- multi-objective
- cell culture
- seed train
language:
- iso: eng
page: 21-48
place: Basel
publication: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
publication_identifier:
  eisbn:
  - 978-3-0365-5209-5
  eissn:
  - 2227-9717
  isbn:
  - 978-3-0365-5210-1
publication_status: published
publisher: MDPI
quality_controlled: '1'
series_title: 'Processes : open access journal'
status: public
title: Designing robust biotechnological processes regarding variabilities using multi-objective
  optimization applied to a biopharmaceutical seed train design
type: book_chapter
user_id: '83781'
volume: special issue
year: '2022'
...
---
_id: '6932'
abstract:
- lang: eng
  text: n order to ensure the safety and security of industrial systems with regard
    to all life cycle phases from development through operation to disposal, specific
    regulatory and normative requirements are imposed. Due to the digitalization,
    interconnection, and constantly increasing complexity of manufacturing systems
    in the context of Industrie 4.0, the manual effort necessary to achieve the required
    safety and security is becoming ever greater and almost impossible to manage,
    especially for small and medium-sized enterprises. Therefore, this paper examines
    the existing challenges in this area in more detail and gives an outlook on the
    possible solutions to ensure safety and security much quicker and with less manual
    effort. The overall vision is a (partially) automated risk assessment of modular
    systems with respect to safety and security, including the alignment of the corresponding
    processes from both domains and the formalization of the information models needed.
author:
- first_name: Marco
  full_name: Ehrlich, Marco
  id: '61562'
  last_name: Ehrlich
- first_name: Andre
  full_name: Bröring, Andre
  id: '65130'
  last_name: Bröring
- first_name: Dimitri
  full_name: Harder, Dimitri
  id: '69147'
  last_name: Harder
- first_name: Torben
  full_name: Auhagen-Meyer, Torben
  last_name: Auhagen-Meyer
- first_name: Philip
  full_name: Kleen, Philip
  id: '44776'
  last_name: Kleen
- first_name: Lukasz
  full_name: Wisniewski, Lukasz
  id: '1710'
  last_name: Wisniewski
- first_name: Henning
  full_name: Trsek, Henning
  id: '1486'
  last_name: Trsek
  orcid: 0000-0002-0133-0656
- first_name: Jürgen
  full_name: Jasperneite, Jürgen
  id: '1899'
  last_name: Jasperneite
citation:
  ama: 'Ehrlich M, Bröring A, Harder D, et al. Alignment of safety and security risk
    assessments for modular production systems. <i>Elektrotechnik und Informationstechnik :
    e &#38; i</i>. 2021;138(6):454-461. doi:<a href="https://doi.org/10.1007/s00502-021-00927-9">10.1007/s00502-021-00927-9</a>'
  apa: 'Ehrlich, M., Bröring, A., Harder, D., Auhagen-Meyer, T., Kleen, P., Wisniewski,
    L., Trsek, H., &#38; Jasperneite, J. (2021). Alignment of safety and security
    risk assessments for modular production systems. <i>Elektrotechnik Und Informationstechnik :
    E &#38; i</i>, <i>138</i>(6), 454–461. <a href="https://doi.org/10.1007/s00502-021-00927-9">https://doi.org/10.1007/s00502-021-00927-9</a>'
  bjps: '<b>Ehrlich M <i>et al.</i></b> (2021) Alignment of Safety and Security Risk
    Assessments for Modular Production Systems. <i>Elektrotechnik und Informationstechnik :
    e &#38; i</i> <b>138</b>, 454–461.'
  chicago: 'Ehrlich, Marco, Andre Bröring, Dimitri Harder, Torben Auhagen-Meyer, Philip
    Kleen, Lukasz Wisniewski, Henning Trsek, and Jürgen Jasperneite. “Alignment of
    Safety and Security Risk Assessments for Modular Production Systems.” <i>Elektrotechnik
    Und Informationstechnik : E &#38; i</i> 138, no. 6 (2021): 454–61. <a href="https://doi.org/10.1007/s00502-021-00927-9">https://doi.org/10.1007/s00502-021-00927-9</a>.'
  chicago-de: 'Ehrlich, Marco, Andre Bröring, Dimitri Harder, Torben Auhagen-Meyer,
    Philip Kleen, Lukasz Wisniewski, Henning Trsek und Jürgen Jasperneite. 2021. Alignment
    of safety and security risk assessments for modular production systems. <i>Elektrotechnik
    und Informationstechnik : e &#38; i</i> 138, Nr. 6: 454–461. doi:<a href="https://doi.org/10.1007/s00502-021-00927-9">10.1007/s00502-021-00927-9</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Ehrlich, Marco</span> ; <span
    style="font-variant:small-caps;">Bröring, Andre</span> ; <span style="font-variant:small-caps;">Harder,
    Dimitri</span> ; <span style="font-variant:small-caps;">Auhagen-Meyer, Torben</span>
    ; <span style="font-variant:small-caps;">Kleen, Philip</span> ; <span style="font-variant:small-caps;">Wisniewski,
    Lukasz</span> ; <span style="font-variant:small-caps;">Trsek, Henning</span> ;
    <span style="font-variant:small-caps;">Jasperneite, Jürgen</span>: Alignment of
    safety and security risk assessments for modular production systems. In: <i>Elektrotechnik
    und Informationstechnik : e &#38; i</i> Bd. 138, Springer (2021), Nr. 6, S. 454–461'
  havard: 'M. Ehrlich, A. Bröring, D. Harder, T. Auhagen-Meyer, P. Kleen, L. Wisniewski,
    H. Trsek, J. Jasperneite, Alignment of safety and security risk assessments for
    modular production systems, Elektrotechnik Und Informationstechnik : E &#38; i.
    138 (2021) 454–461.'
  ieee: 'M. Ehrlich <i>et al.</i>, “Alignment of safety and security risk assessments
    for modular production systems,” <i>Elektrotechnik und Informationstechnik : e
    &#38; i</i>, vol. 138, no. 6, pp. 454–461, 2021, doi: <a href="https://doi.org/10.1007/s00502-021-00927-9">10.1007/s00502-021-00927-9</a>.'
  mla: 'Ehrlich, Marco, et al. “Alignment of Safety and Security Risk Assessments
    for Modular Production Systems.” <i>Elektrotechnik Und Informationstechnik : E
    &#38; i</i>, vol. 138, no. 6, 2021, pp. 454–61, <a href="https://doi.org/10.1007/s00502-021-00927-9">https://doi.org/10.1007/s00502-021-00927-9</a>.'
  short: 'M. Ehrlich, A. Bröring, D. Harder, T. Auhagen-Meyer, P. Kleen, L. Wisniewski,
    H. Trsek, J. Jasperneite, Elektrotechnik Und Informationstechnik : E &#38; i 138
    (2021) 454–461.'
  ufg: '<b>Ehrlich, Marco u. a.</b>: Alignment of safety and security risk assessments
    for modular production systems, in: <i>Elektrotechnik und Informationstechnik :
    e &#38; i</i> 138 (2021), H. 6,  S. 454–461.'
  van: 'Ehrlich M, Bröring A, Harder D, Auhagen-Meyer T, Kleen P, Wisniewski L, et
    al. Alignment of safety and security risk assessments for modular production systems.
    Elektrotechnik und Informationstechnik : e &#38; i. 2021;138(6):454–61.'
date_created: 2021-12-23T17:37:45Z
date_updated: 2025-06-26T13:28:58Z
department:
- _id: DEP5019
- _id: DEP5023
doi: 10.1007/s00502-021-00927-9
external_id:
  isi:
  - '000696142100001'
intvolume: '       138'
isi: '1'
issue: '6'
keyword:
- safety
- security
- alignment
- automation
- processes
- models
language:
- iso: eng
page: 454-461
publication: 'Elektrotechnik und Informationstechnik : e & i'
publication_identifier:
  eissn:
  - 1613-7620
  issn:
  - 0932-383X
publication_status: published
publisher: Springer
status: public
title: Alignment of safety and security risk assessments for modular production systems
type: journal_article
user_id: '83781'
volume: 138
year: '2021'
...
---
_id: '12235'
abstract:
- lang: eng
  text: Metalimnetic oxygen minima are observed in many lakes and reservoirs, but
    the mechanisms behind this phenomena are not well understood. Thus, we simulated
    the metalimnetic oxygen minimum (MOM) in the Rappbode Reservoir with a well-established
    two-dimensional water quality model (CE-QUAL-W2) to systematically quantify the
    chain of events leading to its formation. We used high-resolution measured data
    to calibrate the model, which accurately reproduced the physical (e.g. water level
    and water temperature), biogeochemical (e.g. nutrient and oxygen dynamics) and
    ecological (e.g. algal community dynamics) features of the reservoir, particularly
    the spatial and temporal extent of the MOM. The results indicated that around
    60% of the total oxygen consumption rate in the MOM layer originated from benthic
    processes whereas the remainder originated from pelagic processes. The occurrence
    of the cyanobacterium Planktothrix rubescens in the metalimnion delayed and slightly
    weakened the MOM through photosynthesis, although its decaying biomass ultimately
    induced the MOM. Our research also confirmed the decisive role of water temperature
    in the formation of the MOM since the water temperatures, and thus benthic and
    pelagic oxygen consumption rates, were higher in the metalimnion than in the hypolimnion.
    Our model is not only providing novel conclusions about the drivers of MOM development
    and their quantitative contributions, it is also a new tool for understanding
    and predicting ecological and biogeochemical water quality dynamics.
article_number: '115701'
author:
- first_name: Chenxi
  full_name: Mi, Chenxi
  last_name: Mi
- first_name: Tom
  full_name: Shatwell, Tom
  id: '86424'
  last_name: Shatwell
  orcid: 0000-0002-4520-7916
- first_name: Jun
  full_name: Ma, Jun
  last_name: Ma
- first_name: Valerie Carolin
  full_name: Wentzky, Valerie Carolin
  last_name: Wentzky
- first_name: Bertram
  full_name: Boehrer, Bertram
  last_name: Boehrer
- first_name: Yaqian
  full_name: Xu, Yaqian
  last_name: Xu
- first_name: Karsten
  full_name: Rinke, Karsten
  last_name: Rinke
citation:
  ama: 'Mi C, Shatwell T, Ma J, et al. The formation of a metalimnetic oxygen minimum
    exemplifies how ecosystem dynamics shape biogeochemical processes: A modelling
    study. <i>Water research : a journal of the International Water Association</i>.
    2020;175(5). doi:<a href="https://doi.org/10.1016/j.watres.2020.115701">10.1016/j.watres.2020.115701</a>'
  apa: 'Mi, C., Shatwell, T., Ma, J., Wentzky, V. C., Boehrer, B., Xu, Y., &#38; Rinke,
    K. (2020). The formation of a metalimnetic oxygen minimum exemplifies how ecosystem
    dynamics shape biogeochemical processes: A modelling study. <i>Water Research :
    A Journal of the International Water Association</i>, <i>175</i>(5), Article 115701.
    <a href="https://doi.org/10.1016/j.watres.2020.115701">https://doi.org/10.1016/j.watres.2020.115701</a>'
  bjps: '<b>Mi C <i>et al.</i></b> (2020) The Formation of a Metalimnetic Oxygen Minimum
    Exemplifies How Ecosystem Dynamics Shape Biogeochemical Processes: A Modelling
    Study. <i>Water research : a journal of the International Water Association</i>
    <b>175</b>.'
  chicago: 'Mi, Chenxi, Tom Shatwell, Jun Ma, Valerie Carolin Wentzky, Bertram Boehrer,
    Yaqian Xu, and Karsten Rinke. “The Formation of a Metalimnetic Oxygen Minimum
    Exemplifies How Ecosystem Dynamics Shape Biogeochemical Processes: A Modelling
    Study.” <i>Water Research : A Journal of the International Water Association</i>
    175, no. 5 (2020). <a href="https://doi.org/10.1016/j.watres.2020.115701">https://doi.org/10.1016/j.watres.2020.115701</a>.'
  chicago-de: 'Mi, Chenxi, Tom Shatwell, Jun Ma, Valerie Carolin Wentzky, Bertram
    Boehrer, Yaqian Xu und Karsten Rinke. 2020. The formation of a metalimnetic oxygen
    minimum exemplifies how ecosystem dynamics shape biogeochemical processes: A modelling
    study. <i>Water research : a journal of the International Water Association</i>
    175, Nr. 5. doi:<a href="https://doi.org/10.1016/j.watres.2020.115701">10.1016/j.watres.2020.115701</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Mi, Chenxi</span> ; <span style="font-variant:small-caps;">Shatwell,
    Tom</span> ; <span style="font-variant:small-caps;">Ma, Jun</span> ; <span style="font-variant:small-caps;">Wentzky,
    Valerie Carolin</span> ; <span style="font-variant:small-caps;">Boehrer, Bertram</span>
    ; <span style="font-variant:small-caps;">Xu, Yaqian</span> ; <span style="font-variant:small-caps;">Rinke,
    Karsten</span>: The formation of a metalimnetic oxygen minimum exemplifies how
    ecosystem dynamics shape biogeochemical processes: A modelling study. In: <i>Water
    research : a journal of the International Water Association</i> Bd. 175. Amsterdam,
    Elsevier BV (2020), Nr. 5'
  havard: 'C. Mi, T. Shatwell, J. Ma, V.C. Wentzky, B. Boehrer, Y. Xu, K. Rinke, The
    formation of a metalimnetic oxygen minimum exemplifies how ecosystem dynamics
    shape biogeochemical processes: A modelling study, Water Research : A Journal
    of the International Water Association. 175 (2020).'
  ieee: 'C. Mi <i>et al.</i>, “The formation of a metalimnetic oxygen minimum exemplifies
    how ecosystem dynamics shape biogeochemical processes: A modelling study,” <i>Water
    research : a journal of the International Water Association</i>, vol. 175, no.
    5, Art. no. 115701, 2020, doi: <a href="https://doi.org/10.1016/j.watres.2020.115701">10.1016/j.watres.2020.115701</a>.'
  mla: 'Mi, Chenxi, et al. “The Formation of a Metalimnetic Oxygen Minimum Exemplifies
    How Ecosystem Dynamics Shape Biogeochemical Processes: A Modelling Study.” <i>Water
    Research : A Journal of the International Water Association</i>, vol. 175, no.
    5, 115701, 2020, <a href="https://doi.org/10.1016/j.watres.2020.115701">https://doi.org/10.1016/j.watres.2020.115701</a>.'
  short: 'C. Mi, T. Shatwell, J. Ma, V.C. Wentzky, B. Boehrer, Y. Xu, K. Rinke, Water
    Research : A Journal of the International Water Association 175 (2020).'
  ufg: '<b>Mi, Chenxi u. a.</b>: The formation of a metalimnetic oxygen minimum exemplifies
    how ecosystem dynamics shape biogeochemical processes: A modelling study, in:
    <i>Water research : a journal of the International Water Association</i> 175 (2020),
    H. 5.'
  van: 'Mi C, Shatwell T, Ma J, Wentzky VC, Boehrer B, Xu Y, et al. The formation
    of a metalimnetic oxygen minimum exemplifies how ecosystem dynamics shape biogeochemical
    processes: A modelling study. Water research : a journal of the International
    Water Association. 2020;175(5).'
date_created: 2024-12-08T20:26:00Z
date_updated: 2024-12-09T10:25:49Z
department:
- _id: DEP8022
doi: 10.1016/j.watres.2020.115701
extern: '1'
intvolume: '       175'
issue: '5'
keyword:
- Rappbode reservoir
- CE-QUAL-W2
- Planktothrix rubescens
- Metalimnion
- Oxygen consumption
- Benthic processes
language:
- iso: eng
main_file_link:
- url: https://doi.org/10.1016/j.watres.2020.115701
place: Amsterdam
publication: 'Water research : a journal of the International Water Association'
publication_identifier:
  eissn:
  - 1879-2448
  issn:
  - 0043-1354
publication_status: published
publisher: Elsevier BV
quality_controlled: '1'
status: public
title: 'The formation of a metalimnetic oxygen minimum exemplifies how ecosystem dynamics
  shape biogeochemical processes: A modelling study'
type: scientific_journal_article
user_id: '83781'
volume: 175
year: '2020'
...
---
_id: '12812'
abstract:
- lang: eng
  text: Discerning unexpected from expected data patterns is the key challenge of
    anomaly detection. Although a multitude of solutions has been applied to this
    modern Industry 4.0 problem, it remains an open research issue to identify the
    key characteristics subjacent to an anomaly, sc. generate hypothesis as to why
    they appear. In recent years, machine learning models have been regarded as universal
    solution for a wide range of problems. While most of them suffer from non-self-explanatory
    representations, Gaussian Processes (GPs) deliver interpretable and robust statistical
    data models, which are able to cope with unreliable, noisy, or partially missing
    data. Thus, we regard them as a suitable solution for detecting and appropriately
    representing anomalies and their respective characteristics. In this position
    paper, we discuss the problem of automatic and interpretable anomaly detection
    by means of GPs. That is, we elaborate on why GPs are well suited for anomaly
    detection and what the current challenges are when applying these probabilistic
    models to large-scale production data.
author:
- first_name: Fabian
  full_name: Berns, Fabian
  last_name: Berns
- first_name: Markus
  full_name: Lange-Hegermann, Markus
  id: '71761'
  last_name: Lange-Hegermann
- first_name: Christian
  full_name: Beecks, Christian
  last_name: Beecks
citation:
  ama: Berns F, Lange-Hegermann M, Beecks C. <i>Towards Gaussian Processes for Automatic
    and Interpretable Anomaly Detection in Industry 4.0</i>. (Panetto H, Madani K,
    Smirnov A, eds.). SCITEPRESS - Science and Technology Publications; 2020:87-92.
    doi:<a href="https://doi.org/10.5220/0010130300870092">10.5220/0010130300870092</a>
  apa: Berns, F., Lange-Hegermann, M., &#38; Beecks, C. (2020). Towards Gaussian Processes
    for Automatic and Interpretable Anomaly Detection in Industry 4.0. In H. Panetto,
    K. Madani, &#38; A. Smirnov (Eds.), <i> Proceedings of the International Conference
    on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1</i>
    (pp. 87–92). SCITEPRESS - Science and Technology Publications. <a href="https://doi.org/10.5220/0010130300870092">https://doi.org/10.5220/0010130300870092</a>
  bjps: <b>Berns F, Lange-Hegermann M and Beecks C</b> (2020) <i>Towards Gaussian
    Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0</i>,
    Panetto H, Madani K and Smirnov A (eds). SCITEPRESS - Science and Technology Publications.
  chicago: Berns, Fabian, Markus Lange-Hegermann, and Christian Beecks. <i>Towards
    Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry
    4.0</i>. Edited by H. Panetto, K. Madani, and A. Smirnov. <i> Proceedings of the
    International Conference on Innovative Intelligent Industrial Production and Logistics
    IN4PL - Volume 1</i>. SCITEPRESS - Science and Technology Publications, 2020.
    <a href="https://doi.org/10.5220/0010130300870092">https://doi.org/10.5220/0010130300870092</a>.
  chicago-de: Berns, Fabian, Markus Lange-Hegermann und Christian Beecks. 2020. <i>Towards
    Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry
    4.0</i>. Hg. von H. Panetto, K. Madani, und A. Smirnov. <i> Proceedings of the
    International Conference on Innovative Intelligent Industrial Production and Logistics
    IN4PL - Volume 1</i>. SCITEPRESS - Science and Technology Publications. doi:<a
    href="https://doi.org/10.5220/0010130300870092">10.5220/0010130300870092</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Berns, Fabian</span> ; <span
    style="font-variant:small-caps;">Lange-Hegermann, Markus</span> ; <span style="font-variant:small-caps;">Beecks,
    Christian</span> ; <span style="font-variant:small-caps;">Panetto, H.</span> ;
    <span style="font-variant:small-caps;">Madani, K.</span> ; <span style="font-variant:small-caps;">Smirnov,
    A.</span> (Hrsg.): <i>Towards Gaussian Processes for Automatic and Interpretable
    Anomaly Detection in Industry 4.0</i> : SCITEPRESS - Science and Technology Publications,
    2020'
  havard: F. Berns, M. Lange-Hegermann, C. Beecks, Towards Gaussian Processes for
    Automatic and Interpretable Anomaly Detection in Industry 4.0, SCITEPRESS - Science
    and Technology Publications, 2020.
  ieee: 'F. Berns, M. Lange-Hegermann, and C. Beecks, <i>Towards Gaussian Processes
    for Automatic and Interpretable Anomaly Detection in Industry 4.0</i>. SCITEPRESS
    - Science and Technology Publications, 2020, pp. 87–92. doi: <a href="https://doi.org/10.5220/0010130300870092">10.5220/0010130300870092</a>.'
  mla: Berns, Fabian, et al. “Towards Gaussian Processes for Automatic and Interpretable
    Anomaly Detection in Industry 4.0.” <i> Proceedings of the International Conference
    on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1</i>,
    edited by H. Panetto et al., SCITEPRESS - Science and Technology Publications,
    2020, pp. 87–92, <a href="https://doi.org/10.5220/0010130300870092">https://doi.org/10.5220/0010130300870092</a>.
  short: F. Berns, M. Lange-Hegermann, C. Beecks, Towards Gaussian Processes for Automatic
    and Interpretable Anomaly Detection in Industry 4.0, SCITEPRESS - Science and
    Technology Publications, 2020.
  ufg: '<b>Berns, Fabian/Lange-Hegermann, Markus/Beecks, Christian</b>: Towards Gaussian
    Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0, hg.
    von Panetto, H./Madani, K./Smirnov, A., o. O. 2020.'
  van: Berns F, Lange-Hegermann M, Beecks C. Towards Gaussian Processes for Automatic
    and Interpretable Anomaly Detection in Industry 4.0. Panetto H, Madani K, Smirnov
    A, editors.  Proceedings of the International Conference on Innovative Intelligent
    Industrial Production and Logistics IN4PL - Volume 1. SCITEPRESS - Science and
    Technology Publications; 2020.
conference:
  end_date: 2020-11-04
  location: Budapest, HUNGARY
  name: International Conference on Innovative Intelligent Industrial Production and
    Logistics (IN4PL)
  start_date: 2020-11-02
date_created: 2025-04-17T06:20:07Z
date_updated: 2025-06-26T13:31:38Z
department:
- _id: DEP5000
doi: 10.5220/0010130300870092
editor:
- first_name: H.
  full_name: Panetto, H.
  last_name: Panetto
- first_name: K.
  full_name: Madani, K.
  last_name: Madani
- first_name: A.
  full_name: Smirnov, A.
  last_name: Smirnov
keyword:
- Anomaly Detection
- Gaussian Processes
- Explainable Machine Learning
- Industry 4.0
language:
- iso: eng
page: 87-92
publication: ' Proceedings of the International Conference on Innovative Intelligent
  Industrial Production and Logistics IN4PL - Volume 1'
publication_identifier:
  isbn:
  - 978-989-758-476-3
publication_status: published
publisher: SCITEPRESS - Science and Technology Publications
status: public
title: Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection
  in Industry 4.0
type: conference_editor_article
user_id: '83781'
year: '2020'
...
---
_id: '549'
author:
- first_name: André
  full_name: Springer, André
  id: '71733'
  last_name: Springer
- first_name: Sarah
  full_name: Nothdurft, Sarah
  last_name: Nothdurft
- first_name: Rabi
  full_name: Lahdo, Rabi
  last_name: Lahdo
- first_name: Oliver
  full_name: Seffer, Oliver
  last_name: Seffer
citation:
  ama: 'Springer A, Nothdurft S, Lahdo R, Seffer O. <i>Dissimilar Metal Joints - Laser
    Based Manufacturing Processes for Components of Tomorrow</i>. Lemgo: Technische
    Hochschule Ostwestfalen-Lippe; 2018.'
  apa: 'Springer, A., Nothdurft, S., Lahdo, R., &#38; Seffer, O. (2018). <i>Dissimilar
    Metal Joints - Laser Based Manufacturing Processes for Components of Tomorrow</i>.
    <i>8th International Conference on Production Engineering and Management</i>.
    Lemgo: Technische Hochschule Ostwestfalen-Lippe.'
  bjps: '<b>Springer A <i>et al.</i></b> (2018) <i>Dissimilar Metal Joints - Laser
    Based Manufacturing Processes for Components of Tomorrow</i>. Lemgo: Technische
    Hochschule Ostwestfalen-Lippe.'
  chicago: 'Springer, André, Sarah Nothdurft, Rabi Lahdo, and Oliver Seffer. <i>Dissimilar
    Metal Joints - Laser Based Manufacturing Processes for Components of Tomorrow</i>.
    <i>8th International Conference on Production Engineering and Management</i>.
    Lemgo: Technische Hochschule Ostwestfalen-Lippe, 2018.'
  chicago-de: 'Springer, André, Sarah Nothdurft, Rabi Lahdo und Oliver Seffer. 2018.
    <i>Dissimilar Metal Joints - Laser Based Manufacturing Processes for Components
    of Tomorrow</i>. <i>8th International Conference on Production Engineering and
    Management</i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe.'
  din1505-2-1: '<span style="font-variant:small-caps;">Springer, André</span> ; <span
    style="font-variant:small-caps;">Nothdurft, Sarah</span> ; <span style="font-variant:small-caps;">Lahdo,
    Rabi</span> ; <span style="font-variant:small-caps;">Seffer, Oliver</span>: <i>Dissimilar
    Metal Joints - Laser Based Manufacturing Processes for Components of Tomorrow</i>.
    Lemgo : Technische Hochschule Ostwestfalen-Lippe, 2018'
  havard: A. Springer, S. Nothdurft, R. Lahdo, O. Seffer, Dissimilar Metal Joints
    - Laser Based Manufacturing Processes for Components of Tomorrow, Technische Hochschule
    Ostwestfalen-Lippe, Lemgo, 2018.
  ieee: 'A. Springer, S. Nothdurft, R. Lahdo, and O. Seffer, <i>Dissimilar Metal Joints
    - Laser Based Manufacturing Processes for Components of Tomorrow</i>. Lemgo: Technische
    Hochschule Ostwestfalen-Lippe, 2018.'
  mla: Springer, André, et al. “Dissimilar Metal Joints - Laser Based Manufacturing
    Processes for Components of Tomorrow.” <i>8th International Conference on Production
    Engineering and Management</i>, Technische Hochschule Ostwestfalen-Lippe, 2018.
  short: A. Springer, S. Nothdurft, R. Lahdo, O. Seffer, Dissimilar Metal Joints -
    Laser Based Manufacturing Processes for Components of Tomorrow, Technische Hochschule
    Ostwestfalen-Lippe, Lemgo, 2018.
  ufg: '<b>Springer, André et. al. (2018)</b>: Dissimilar Metal Joints - Laser Based
    Manufacturing Processes for Components of Tomorrow, Lemgo.'
  van: 'Springer A, Nothdurft S, Lahdo R, Seffer O. Dissimilar Metal Joints - Laser
    Based Manufacturing Processes for Components of Tomorrow. 8th International Conference
    on Production Engineering and Management. Lemgo: Technische Hochschule Ostwestfalen-Lippe;
    2018.'
conference:
  end_date: 2018-10-05
  location: Lemgo
  name: 8th International Conference
  start_date: 2018-10-04
date_created: 2019-02-13T13:42:56Z
date_updated: 2023-03-15T13:49:59Z
department:
- _id: DEP1306
- _id: DEP7037
keyword:
- Dissimilar metal joints
- Laser processes
- Multi-material components
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.hs-owl.de/fileadmin/diman/Veroeffentlichungen/PEM2018_proceedings_web.pdf
oa: '1'
place: Lemgo
publication: 8th International Conference on Production Engineering and Management
publication_identifier:
  isbn:
  - 978-3-946856-03-0
publication_status: published
publisher: Technische Hochschule Ostwestfalen-Lippe
related_material:
  link:
  - relation: contains
    url: https://www.hs-owl.de/fileadmin/diman/Veroeffentlichungen/PEM2018_proceedings_web.pdf
status: public
title: Dissimilar Metal Joints - Laser Based Manufacturing Processes for Components
  of Tomorrow
type: conference_editor_article
user_id: '79260'
year: 2018
...
---
_id: '4255'
abstract:
- lang: eng
  text: Increasingly, production processes are enabled and controlled by Information
    Technology (IT), a development being also referred to as “Industry 4.0”. IT thereby
    contributes to flexible and adaptive production processes, and in this sense factories
    become “smart factories”. In line with this, IT also more and more supports human
    workers via various assistance systems. This support aims to both support workers
    to better execute their tasks and to reduce the effort and time required when
    working. However, due to the large spectrum of assistance systems, it is hard
    to acquire an overview and to select an adequate system for a smart factory based
    on meaningful criteria. We therefore synthesize a set of comparison criteria into
    a consistent framework and demonstrate the application of our framework by classifying
    three examples.
author:
- first_name: Michael
  full_name: Fellmann, Michael
  last_name: Fellmann
- first_name: Sebastian
  full_name: Robert, Sebastian
  last_name: Robert
- first_name: Sebastian
  full_name: Büttner, Sebastian
  id: '61868'
  last_name: Büttner
- first_name: Henrik
  full_name: Mucha, Henrik
  id: '64896'
  last_name: Mucha
- first_name: Carsten
  full_name: Röcker, Carsten
  id: '61525'
  last_name: Röcker
citation:
  ama: 'Fellmann M, Robert S, Büttner S, Mucha H, Röcker C. Towards a Framework for
    Assistance Systems to Support Work Processes in Smart Factories. In: Holzinger
    A, ed. <i> Machine Learning and Knowledge Extraction : First IFIP TC 5, WG 8.4,
    8.9, 12.9 International Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy,
    August 29 – September 1, 2017, Proceedings</i>. Vol 10410. Lecture Notes in Computer
    Science . Cham: Springer; 2017:59-68. doi:<a href="https://doi.org/10.1007/978-3-319-66808-6_5">10.1007/978-3-319-66808-6_5</a>'
  apa: 'Fellmann, M., Robert, S., Büttner, S., Mucha, H., &#38; Röcker, C. (2017).
    Towards a Framework for Assistance Systems to Support Work Processes in Smart
    Factories. In A. Holzinger (Ed.), <i> Machine Learning and Knowledge Extraction :
    First IFIP TC 5, WG 8.4, 8.9, 12.9 International Cross-Domain Conference, CD-MAKE
    2017, Reggio, Italy, August 29 – September 1, 2017, Proceedings</i> (Vol. 10410,
    pp. 59–68). Cham: Springer. <a href="https://doi.org/10.1007/978-3-319-66808-6_5">https://doi.org/10.1007/978-3-319-66808-6_5</a>'
  bjps: '<b>Fellmann M <i>et al.</i></b> (2017) Towards a Framework for Assistance
    Systems to Support Work Processes in Smart Factories. In Holzinger A (ed.), <i>
    Machine Learning and Knowledge Extraction : First IFIP TC 5, WG 8.4, 8.9, 12.9
    International Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy, August 29
    – September 1, 2017, Proceedings</i>, vol. 10410. Cham: Springer, pp. 59–68.'
  chicago: 'Fellmann, Michael, Sebastian Robert, Sebastian Büttner, Henrik Mucha,
    and Carsten Röcker. “Towards a Framework for Assistance Systems to Support Work
    Processes in Smart Factories.” In <i> Machine Learning and Knowledge Extraction :
    First IFIP TC 5, WG 8.4, 8.9, 12.9 International Cross-Domain Conference, CD-MAKE
    2017, Reggio, Italy, August 29 – September 1, 2017, Proceedings</i>, edited by
    Andreas Holzinger, 10410:59–68. Lecture Notes in Computer Science . Cham: Springer,
    2017. <a href="https://doi.org/10.1007/978-3-319-66808-6_5">https://doi.org/10.1007/978-3-319-66808-6_5</a>.'
  chicago-de: 'Fellmann, Michael, Sebastian Robert, Sebastian Büttner, Henrik Mucha
    und Carsten Röcker. 2017. Towards a Framework for Assistance Systems to Support
    Work Processes in Smart Factories. In: <i> Machine Learning and Knowledge Extraction :
    First IFIP TC 5, WG 8.4, 8.9, 12.9 International Cross-Domain Conference, CD-MAKE
    2017, Reggio, Italy, August 29 – September 1, 2017, Proceedings</i>, hg. von Andreas
    Holzinger, 10410:59–68. Lecture Notes in Computer Science . Cham: Springer. doi:<a
    href="https://doi.org/10.1007/978-3-319-66808-6_5,">10.1007/978-3-319-66808-6_5,</a>
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Fellmann, Michael</span> ;
    <span style="font-variant:small-caps;">Robert, Sebastian</span> ; <span style="font-variant:small-caps;">Büttner,
    Sebastian</span> ; <span style="font-variant:small-caps;">Mucha, Henrik</span>
    ; <span style="font-variant:small-caps;">Röcker, Carsten</span>: Towards a Framework
    for Assistance Systems to Support Work Processes in Smart Factories. In: <span
    style="font-variant:small-caps;">Holzinger, A.</span> (Hrsg.): <i> Machine Learning
    and Knowledge Extraction : First IFIP TC 5, WG 8.4, 8.9, 12.9 International Cross-Domain
    Conference, CD-MAKE 2017, Reggio, Italy, August 29 – September 1, 2017, Proceedings</i>,
    <i>Lecture Notes in Computer Science </i>. Bd. 10410. Cham : Springer, 2017, S. 59–68'
  havard: 'M. Fellmann, S. Robert, S. Büttner, H. Mucha, C. Röcker, Towards a Framework
    for Assistance Systems to Support Work Processes in Smart Factories, in: A. Holzinger
    (Ed.),  Machine Learning and Knowledge Extraction : First IFIP TC 5, WG 8.4, 8.9,
    12.9 International Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy, August
    29 – September 1, 2017, Proceedings, Springer, Cham, 2017: pp. 59–68.'
  ieee: 'M. Fellmann, S. Robert, S. Büttner, H. Mucha, and C. Röcker, “Towards a Framework
    for Assistance Systems to Support Work Processes in Smart Factories,” in <i> Machine
    Learning and Knowledge Extraction : First IFIP TC 5, WG 8.4, 8.9, 12.9 International
    Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy, August 29 – September 1,
    2017, Proceedings</i>, Reggio, Italy, 2017, vol. 10410, pp. 59–68.'
  mla: 'Fellmann, Michael, et al. “Towards a Framework for Assistance Systems to Support
    Work Processes in Smart Factories.” <i> Machine Learning and Knowledge Extraction :
    First IFIP TC 5, WG 8.4, 8.9, 12.9 International Cross-Domain Conference, CD-MAKE
    2017, Reggio, Italy, August 29 – September 1, 2017, Proceedings</i>, edited by
    Andreas Holzinger, vol. 10410, Springer, 2017, pp. 59–68, doi:<a href="https://doi.org/10.1007/978-3-319-66808-6_5">10.1007/978-3-319-66808-6_5</a>.'
  short: 'M. Fellmann, S. Robert, S. Büttner, H. Mucha, C. Röcker, in: A. Holzinger
    (Ed.),  Machine Learning and Knowledge Extraction : First IFIP TC 5, WG 8.4, 8.9,
    12.9 International Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy, August
    29 – September 1, 2017, Proceedings, Springer, Cham, 2017, pp. 59–68.'
  ufg: '<b>Fellmann, Michael et. al. (2017)</b>: Towards a Framework for Assistance
    Systems to Support Work Processes in Smart Factories, in: Andreas Holzinger (Hg.):
    <i> Machine Learning and Knowledge Extraction : First IFIP TC 5, WG 8.4, 8.9,
    12.9 International Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy, August
    29 – September 1, 2017, Proceedings</i> (=<i>Lecture Notes in Computer Science  10410</i>),
    Cham, S. 59–68.'
  van: 'Fellmann M, Robert S, Büttner S, Mucha H, Röcker C. Towards a Framework for
    Assistance Systems to Support Work Processes in Smart Factories. In: Holzinger
    A, editor.  Machine Learning and Knowledge Extraction : First IFIP TC 5, WG 84,
    89, 129 International Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy, August
    29 – September 1, 2017, Proceedings. Cham: Springer; 2017. p. 59–68. (Lecture
    Notes in Computer Science ; vol. 10410).'
conference:
  end_date: 2017-09-01
  location: Reggio, Italy
  name: International Cross-Domain Conference, CD-MAKE 2017
  start_date: 2017-08-29
date_created: 2020-12-10T13:40:05Z
date_updated: 2023-03-15T13:49:51Z
department:
- _id: DEP5023
doi: 10.1007/978-3-319-66808-6_5
editor:
- first_name: Andreas
  full_name: Holzinger, Andreas
  last_name: Holzinger
intvolume: '     10410'
keyword:
- Assistance systems
- Smart factory
- Production processes
language:
- iso: eng
main_file_link:
- open_access: '1'
oa: '1'
page: 59-68
place: Cham
publication: ' Machine Learning and Knowledge Extraction : First IFIP TC 5, WG 8.4,
  8.9, 12.9 International Cross-Domain Conference, CD-MAKE 2017, Reggio, Italy, August
  29 – September 1, 2017, Proceedings'
publication_identifier:
  eisbn:
  - '9783319668086 '
  isbn:
  - 978-3-319-66807-9
publication_status: published
publisher: Springer
series_title: 'Lecture Notes in Computer Science '
status: public
title: Towards a Framework for Assistance Systems to Support Work Processes in Smart
  Factories
type: conference
user_id: '15514'
volume: 10410
year: 2017
...
---
_id: '4330'
abstract:
- lang: eng
  text: Catchwords such as “Cyber-Physical-Systems” and “Industry 4.0” describe the
    current development of systems with embedded intelligence. These systems can be
    characterized by an increasing technical complexity that must be addressed in
    the user interface. In this paper we analyze the specific requirements posed by
    the interaction with cyber-physical-systems, present a coordinated approach to
    these requirements and illustrate our approach with a practical example of an
    assistance system for assembly workers in an industrial production environment.
author:
- first_name: Volker
  full_name: Paelke, Volker
  last_name: Paelke
- first_name: Carsten
  full_name: Röcker, Carsten
  id: '61525'
  last_name: Röcker
citation:
  ama: 'Paelke V, Röcker C. User Interfaces for Cyber-Physical Systems: Challenges
    and Possible Approaches. . In: <i>Design, User Experience, and Usability: Design
    Discourse</i>. Vol 9186. Lecture Notes in Computer Science ;  Information Systems
    and Applications, incl. Internet/Web, and HCI. Springer; 2015:75-85. doi:<a href="https://doi.org/10.1007/978-3-319-20886-2_8">10.1007/978-3-319-20886-2_8</a>'
  apa: 'Paelke, V., &#38; Röcker, C. (2015). User Interfaces for Cyber-Physical Systems:
    Challenges and Possible Approaches. . <i>Design, User Experience, and Usability:
    Design Discourse</i>, <i>9186</i>, 75–85. <a href="https://doi.org/10.1007/978-3-319-20886-2_8">https://doi.org/10.1007/978-3-319-20886-2_8</a>'
  bjps: '<b>Paelke V and Röcker C</b> (2015) User Interfaces for Cyber-Physical Systems:
    Challenges and Possible Approaches. . <i>Design, User Experience, and Usability:
    Design Discourse</i>, vol. 9186. Cham: Springer, pp. 75–85.'
  chicago: 'Paelke, Volker, and Carsten Röcker. “User Interfaces for Cyber-Physical
    Systems: Challenges and Possible Approaches. .” In <i>Design, User Experience,
    and Usability: Design Discourse</i>, 9186:75–85. Lecture Notes in Computer Science ; 
    Information Systems and Applications, Incl. Internet/Web, and HCI. Cham: Springer,
    2015. <a href="https://doi.org/10.1007/978-3-319-20886-2_8">https://doi.org/10.1007/978-3-319-20886-2_8</a>.'
  chicago-de: 'Paelke, Volker und Carsten Röcker. 2015. User Interfaces for Cyber-Physical
    Systems: Challenges and Possible Approaches. . In: <i>Design, User Experience,
    and Usability: Design Discourse</i>, 9186:75–85. Lecture Notes in Computer Science ; 
    Information Systems and Applications, incl. Internet/Web, and HCI. Cham: Springer.
    doi:<a href="https://doi.org/10.1007/978-3-319-20886-2_8">10.1007/978-3-319-20886-2_8</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Paelke, Volker</span> ; <span
    style="font-variant:small-caps;">Röcker, Carsten</span>: User Interfaces for Cyber-Physical
    Systems: Challenges and Possible Approaches. . In: <i>Design, User Experience,
    and Usability: Design Discourse</i>, <i>Lecture Notes in Computer Science ;  Information
    Systems and Applications, incl. Internet/Web, and HCI</i>. Bd. 9186. Cham : Springer,
    2015, S. 75–85'
  havard: 'V. Paelke, C. Röcker, User Interfaces for Cyber-Physical Systems: Challenges
    and Possible Approaches. , in: Design, User Experience, and Usability: Design
    Discourse, Springer, Cham, 2015: pp. 75–85.'
  ieee: 'V. Paelke and C. Röcker, “User Interfaces for Cyber-Physical Systems: Challenges
    and Possible Approaches. ,” in <i>Design, User Experience, and Usability: Design
    Discourse</i>, Los Angeles, CA, USA, 2015, vol. 9186, pp. 75–85. doi: <a href="https://doi.org/10.1007/978-3-319-20886-2_8">10.1007/978-3-319-20886-2_8</a>.'
  mla: 'Paelke, Volker, and Carsten Röcker. “User Interfaces for Cyber-Physical Systems:
    Challenges and Possible Approaches. .” <i>Design, User Experience, and Usability:
    Design Discourse</i>, vol. 9186, Springer, 2015, pp. 75–85, <a href="https://doi.org/10.1007/978-3-319-20886-2_8">https://doi.org/10.1007/978-3-319-20886-2_8</a>.'
  short: 'V. Paelke, C. Röcker, in: Design, User Experience, and Usability: Design
    Discourse, Springer, Cham, 2015, pp. 75–85.'
  ufg: '<b>Paelke, Volker/Röcker, Carsten</b>: User Interfaces for Cyber-Physical
    Systems: Challenges and Possible Approaches. , in: o. Hg.: Design, User Experience,
    and Usability: Design Discourse, Bd. 9186, Cham 2015 (Lecture Notes in Computer
    Science ;  Information Systems and Applications, incl. Internet/Web, and HCI), 
    S. 75–85.'
  van: 'Paelke V, Röcker C. User Interfaces for Cyber-Physical Systems: Challenges
    and Possible Approaches. . In: Design, User Experience, and Usability: Design
    Discourse. Cham: Springer; 2015. p. 75–85. (Lecture Notes in Computer Science ; 
    Information Systems and Applications, incl. Internet/Web, and HCI; vol. 9186).'
conference:
  end_date: 2015-08-07
  location: Los Angeles, CA, USA
  name: 4th International Conference, DUXU 2015, Held as Part of HCI International
    2015
  start_date: 2015-08-02
date_created: 2021-01-08T12:03:44Z
date_updated: 2025-04-11T09:03:04Z
department:
- _id: DEP5023
doi: 10.1007/978-3-319-20886-2_8
intvolume: '      9186'
keyword:
- Industrial IT
- User-Centered design
- Usability
- User interfaces
- Cyber-Physical-Systems
- Industry 4.0
- Augmented reality
- Development processes and methods
language:
- iso: eng
page: '75-85 '
place: Cham
publication: 'Design, User Experience, and Usability: Design Discourse'
publication_identifier:
  eisbn:
  - 978-3-319-20886-2
  isbn:
  - 978-3-319-20885-5
publication_status: published
publisher: Springer
series_title: Lecture Notes in Computer Science ;  Information Systems and Applications,
  incl. Internet/Web, and HCI
status: public
title: 'User Interfaces for Cyber-Physical Systems: Challenges and Possible Approaches. '
type: conference
user_id: '83781'
volume: 9186
year: '2015'
...
---
_id: '10164'
abstract:
- lang: eng
  text: Cognitive radios (CR) can sense and detect temporarily available spectral
    holes for an opportunistic operation to improve the spectral efficiency and coexistence
    of industrial radio systems. It will be of particular interest for a CR system
    to apply predictive modeling in order to forecast the behavior of the coexisting
    environment. A secondary cognitive user shall use preemptive tuning of its operating
    parameters following the predictive model. However, a considerable challenge is
    to generate an accurate model and predict efficiently in order to meet strict
    time related requirements of industrial applications. Such predictive modeling
    has already gained some attention but real-time experimental results have never
    been reported to the best of our knowledge. In this contribution we investigate
    the performance of a Markov model based CR system using simulative and experimental
    environments for its application in industrial systems.
author:
- first_name: Kaleem
  full_name: Ahmad, Kaleem
  last_name: Ahmad
- first_name: Uwe
  full_name: Meier, Uwe
  id: '1143'
  last_name: Meier
- first_name: Stefan
  full_name: Witte, Stefan
  id: '1605'
  last_name: Witte
citation:
  ama: Ahmad K, Meier U, Witte S. <i>Predictive Oppertunistic Spectrum Access Using
    Markov Models</i>. (Institute of Electrical and Electronics Engineers, IEEE Industrial
    Electronics Society, eds.). IEEE; 2012. doi:<a href="https://doi.org/10.1109/ETFA.2012.6489557">10.1109/ETFA.2012.6489557</a>
  apa: Ahmad, K., Meier, U., &#38; Witte, S. (2012). Predictive Oppertunistic Spectrum
    Access Using Markov Models. In Institute of Electrical and Electronics Engineers
    &#38; IEEE Industrial Electronics Society (Eds.), <i>Proceedings of 2012 IEEE
    17th International Conference on Emerging Technologies &#38; Factory Automation
    (ETFA 2012)</i>. IEEE. <a href="https://doi.org/10.1109/ETFA.2012.6489557">https://doi.org/10.1109/ETFA.2012.6489557</a>
  bjps: '<b>Ahmad K, Meier U and Witte S</b> (2012) <i>Predictive Oppertunistic Spectrum
    Access Using Markov Models</i>, Institute of Electrical and Electronics Engineers
    and IEEE Industrial Electronics Society (eds). Piscataway, NJ: IEEE.'
  chicago: 'Ahmad, Kaleem, Uwe Meier, and Stefan Witte. <i>Predictive Oppertunistic
    Spectrum Access Using Markov Models</i>. Edited by Institute of Electrical and
    Electronics Engineers and IEEE Industrial Electronics Society. <i>Proceedings
    of 2012 IEEE 17th International Conference on Emerging Technologies &#38; Factory
    Automation (ETFA 2012)</i>. Piscataway, NJ: IEEE, 2012. <a href="https://doi.org/10.1109/ETFA.2012.6489557">https://doi.org/10.1109/ETFA.2012.6489557</a>.'
  chicago-de: 'Ahmad, Kaleem, Uwe Meier und Stefan Witte. 2012. <i>Predictive Oppertunistic
    Spectrum Access Using Markov Models</i>. Hg. von Institute of Electrical and Electronics
    Engineers und IEEE Industrial Electronics Society. <i>Proceedings of 2012 IEEE
    17th International Conference on Emerging Technologies &#38; Factory Automation
    (ETFA 2012)</i>. Piscataway, NJ: IEEE. doi:<a href="https://doi.org/10.1109/ETFA.2012.6489557">10.1109/ETFA.2012.6489557</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Ahmad, Kaleem</span> ; <span
    style="font-variant:small-caps;">Meier, Uwe</span> ; <span style="font-variant:small-caps;">Witte,
    Stefan</span> ; <span style="font-variant:small-caps;">Institute of Electrical
    and Electronics Engineers</span> ; <span style="font-variant:small-caps;">IEEE
    Industrial Electronics Society</span> (Hrsg.): <i>Predictive Oppertunistic Spectrum
    Access Using Markov Models</i>. Piscataway, NJ : IEEE, 2012'
  havard: K. Ahmad, U. Meier, S. Witte, Predictive Oppertunistic Spectrum Access Using
    Markov Models, IEEE, Piscataway, NJ, 2012.
  ieee: 'K. Ahmad, U. Meier, and S. Witte, <i>Predictive Oppertunistic Spectrum Access
    Using Markov Models</i>. Piscataway, NJ: IEEE, 2012. doi: <a href="https://doi.org/10.1109/ETFA.2012.6489557">10.1109/ETFA.2012.6489557</a>.'
  mla: Ahmad, Kaleem, et al. “Predictive Oppertunistic Spectrum Access Using Markov
    Models.” <i>Proceedings of 2012 IEEE 17th International Conference on Emerging
    Technologies &#38; Factory Automation (ETFA 2012)</i>, edited by Institute of
    Electrical and Electronics Engineers and IEEE Industrial Electronics Society,
    IEEE, 2012, <a href="https://doi.org/10.1109/ETFA.2012.6489557">https://doi.org/10.1109/ETFA.2012.6489557</a>.
  short: K. Ahmad, U. Meier, S. Witte, Predictive Oppertunistic Spectrum Access Using
    Markov Models, IEEE, Piscataway, NJ, 2012.
  ufg: '<b>Ahmad, Kaleem/Meier, Uwe/Witte, Stefan</b>: Predictive Oppertunistic Spectrum
    Access Using Markov Models, hg. von Institute of Electrical and Electronics Engineers,
    IEEE Industrial Electronics Society, Piscataway, NJ 2012.'
  van: 'Ahmad K, Meier U, Witte S. Predictive Oppertunistic Spectrum Access Using
    Markov Models. Institute of Electrical and Electronics Engineers, IEEE Industrial
    Electronics Society, editors. Proceedings of 2012 IEEE 17th International Conference
    on Emerging Technologies &#38; Factory Automation (ETFA 2012). Piscataway, NJ:
    IEEE; 2012.'
conference:
  end_date: 2012-09-21
  location: 'Krakow, Poland '
  name: 17th IEEE Conference on Emerging Technologies and Factory Automation
  start_date: 2012-09-17
corporate_editor:
- Institute of Electrical and Electronics Engineers
- IEEE Industrial Electronics Society
date_created: 2023-07-27T10:53:31Z
date_updated: 2023-08-03T09:05:56Z
department:
- _id: DEP5000
- _id: DEP5023
doi: 10.1109/ETFA.2012.6489557
keyword:
- cognitive radio
- Markov processes
- radio spectrum management
language:
- iso: eng
place: Piscataway, NJ
publication: Proceedings of 2012 IEEE 17th International Conference on Emerging Technologies
  & Factory Automation (ETFA 2012)
publication_identifier:
  eisbn:
  - 978-1-4673-4737-2
  isbn:
  - '978-1-4673-4735-8 '
publication_status: published
publisher: IEEE
status: public
title: Predictive Oppertunistic Spectrum Access Using Markov Models
type: conference_editor_article
user_id: '83781'
year: '2012'
...
