---
_id: '12706'
abstract:
- lang: eng
  text: Vaseline, also referred to as petrolatum, is a colloidal dispersion of liquid-crystalline
    structures of hydrocarbons derived from petroleum. It has long been recognized
    for its versatile applications in the pharmaceutical industry, with its use in
    the formulation of various topical medications, wound care products, and drug
    delivery systems. For pharmaceutical use, petrolatum has to meet the quality standards
    described in its Pharmacopoeia monograph. The comprised test ranges allow for
    a broad range of Vaseline qualities on the market, while the tests themselves
    only poorly discriminate between grades. The only differentiating properties are
    related to the melting behavior, which is tested via drop point analysis, and
    the consistency, addressed in the functionality-related characteristics section.
    In this study, we propose the hypothesis that Near-infrared spectroscopy (NIRS)
    could be a comparably simple method to evaluate the crystalline behavior of Vaseline
    qualities. We expect such information to provide additional details for Vaseline
    quality discrimination. This discrimination would allow the most suitable petroleum
    jelly to be selected for an existing formulation when the previous one needs to
    be replaced; for example, due to a manufacturer change. We demonstrate that NIRS
    in transmission and reflectance mode obtained by traditional continuous spectra
    acquisition and fragmented NIR spectra acquisition through multi-optical, multi-modal
    excitation, respectively, can both serve as a basis for detecting Vaseline quality
    differences, which we have further proven by thermal analysis and tests with semisolid
    formulations. Additionally, we demonstrate that a lower-cost multi-optical spectrometer
    in reflectance mode can detect Vaseline quality differences in rotated samples.
author:
- first_name: Niels Hendrik
  full_name: Fliedner, Niels Hendrik
  last_name: Fliedner
- first_name: Volker
  full_name: Lohweg, Volker
  last_name: Lohweg
- first_name: Claudia
  full_name: Al-Karawi, Claudia
  last_name: Al-Karawi
- first_name: Miriam
  full_name: Pein-Hackelbusch, Miriam
  last_name: Pein-Hackelbusch
citation:
  ama: Fliedner NH, Lohweg V, Al-Karawi C, Pein-Hackelbusch M. <i>A Novel Spectroscopic
    Approach for Vaseline Quality Discrimination</i>. (Dörksen H, Scanzio S, Jasperneite
    J, et al., eds.). IEEE; 2023. doi:<a href="https://doi.org/10.1109/indin51400.2023.10218318">10.1109/indin51400.2023.10218318</a>
  apa: Fliedner, N. H., Lohweg, V., Al-Karawi, C., &#38; Pein-Hackelbusch, M. (2023).
    A Novel Spectroscopic Approach for Vaseline Quality Discrimination. In H. Dörksen,
    S. Scanzio, J. Jasperneite, L. Wisniewski, K. F. Man, T. Sauter, L. Seno, H. Trsek,
    V. Vyatkin, &#38; Institute of Electrical and Electronics Engineers  (Eds.), <i>2023
    IEEE 21st International Conference on Industrial Informatics (INDIN)</i>. IEEE.
    <a href="https://doi.org/10.1109/indin51400.2023.10218318">https://doi.org/10.1109/indin51400.2023.10218318</a>
  bjps: '<b>Fliedner NH <i>et al.</i></b> (2023) <i>A Novel Spectroscopic Approach
    for Vaseline Quality Discrimination</i>, Dörksen H et al. (eds). [Piscataway,
    NJ] : IEEE.'
  chicago: 'Fliedner, Niels Hendrik, Volker Lohweg, Claudia Al-Karawi, and Miriam
    Pein-Hackelbusch. <i>A Novel Spectroscopic Approach for Vaseline Quality Discrimination</i>.
    Edited by Helene Dörksen, Stefano  Scanzio, Jürgen Jasperneite, Lukasz Wisniewski,
    Kim Fung  Man, Thilo  Sauter, Lucia  Seno, Henning Trsek, Valeriy  Vyatkin, and
    Institute of Electrical and Electronics Engineers . <i>2023 IEEE 21st International
    Conference on Industrial Informatics (INDIN)</i>. [Piscataway, NJ] : IEEE, 2023.
    <a href="https://doi.org/10.1109/indin51400.2023.10218318">https://doi.org/10.1109/indin51400.2023.10218318</a>.'
  chicago-de: 'Fliedner, Niels Hendrik, Volker Lohweg, Claudia Al-Karawi und Miriam
    Pein-Hackelbusch. 2023. <i>A Novel Spectroscopic Approach for Vaseline Quality
    Discrimination</i>. Hg. von Helene Dörksen, Stefano  Scanzio, Jürgen Jasperneite,
    Lukasz Wisniewski, Kim Fung  Man, Thilo  Sauter, Lucia  Seno, Henning Trsek, Valeriy  Vyatkin,
    und Institute of Electrical and Electronics Engineers . <i>2023 IEEE 21st International
    Conference on Industrial Informatics (INDIN)</i>. [Piscataway, NJ] : IEEE. doi:<a
    href="https://doi.org/10.1109/indin51400.2023.10218318">10.1109/indin51400.2023.10218318</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Fliedner, Niels Hendrik</span>
    ; <span style="font-variant:small-caps;">Lohweg, Volker</span> ; <span style="font-variant:small-caps;">Al-Karawi,
    Claudia</span> ; <span style="font-variant:small-caps;">Pein-Hackelbusch, Miriam</span>
    ; <span style="font-variant:small-caps;"><span style="font-variant:small-caps;">Dörksen,
    H.</span> ; <span style="font-variant:small-caps;">Scanzio, S.</span> ; <span
    style="font-variant:small-caps;">Jasperneite, J.</span> ; <span style="font-variant:small-caps;">Wisniewski,
    L.</span> ; <span style="font-variant:small-caps;">Man, K. F.</span> ; <span style="font-variant:small-caps;">Sauter,
    T.</span> ; <span style="font-variant:small-caps;">Seno, L.</span> ; <span style="font-variant:small-caps;">Trsek,
    H.</span> ; u. a.</span> (Hrsg.): <i>A Novel Spectroscopic Approach for Vaseline
    Quality Discrimination</i>. [Piscataway, NJ]  : IEEE, 2023'
  havard: N.H. Fliedner, V. Lohweg, C. Al-Karawi, M. Pein-Hackelbusch, A Novel Spectroscopic
    Approach for Vaseline Quality Discrimination, IEEE, [Piscataway, NJ] , 2023.
  ieee: 'N. H. Fliedner, V. Lohweg, C. Al-Karawi, and M. Pein-Hackelbusch, <i>A Novel
    Spectroscopic Approach for Vaseline Quality Discrimination</i>. [Piscataway, NJ]
    : IEEE, 2023. doi: <a href="https://doi.org/10.1109/indin51400.2023.10218318">10.1109/indin51400.2023.10218318</a>.'
  mla: Fliedner, Niels Hendrik, et al. “A Novel Spectroscopic Approach for Vaseline
    Quality Discrimination.” <i>2023 IEEE 21st International Conference on Industrial
    Informatics (INDIN)</i>, edited by Helene Dörksen et al., IEEE, 2023, <a href="https://doi.org/10.1109/indin51400.2023.10218318">https://doi.org/10.1109/indin51400.2023.10218318</a>.
  short: N.H. Fliedner, V. Lohweg, C. Al-Karawi, M. Pein-Hackelbusch, A Novel Spectroscopic
    Approach for Vaseline Quality Discrimination, IEEE, [Piscataway, NJ] , 2023.
  ufg: '<b>Fliedner, Niels Hendrik u. a.</b>: A Novel Spectroscopic Approach for Vaseline
    Quality Discrimination, hg. von Dörksen, Helene u. a., [Piscataway, NJ]  2023.'
  van: 'Fliedner NH, Lohweg V, Al-Karawi C, Pein-Hackelbusch M. A Novel Spectroscopic
    Approach for Vaseline Quality Discrimination. Dörksen H, Scanzio S, Jasperneite
    J, Wisniewski L, Man KF, Sauter T, et al., editors. 2023 IEEE 21st International
    Conference on Industrial Informatics (INDIN). [Piscataway, NJ] : IEEE; 2023.'
conference:
  end_date: 2023-07-20
  location: Lemgo
  name: 21st International Conference on Industrial Informatics (INDIN 2023)
  start_date: 2023-07-18
corporate_editor:
- 'Institute of Electrical and Electronics Engineers '
date_created: 2025-03-13T13:48:58Z
date_updated: 2025-03-13T14:44:34Z
department:
- _id: DEP5019
- _id: DEP5023
doi: 10.1109/indin51400.2023.10218318
editor:
- first_name: Helene
  full_name: Dörksen, Helene
  id: '46416'
  last_name: Dörksen
- first_name: 'Stefano '
  full_name: 'Scanzio, Stefano '
  last_name: Scanzio
- first_name: Jürgen
  full_name: Jasperneite, Jürgen
  id: '1899'
  last_name: Jasperneite
- first_name: Lukasz
  full_name: Wisniewski, Lukasz
  id: '1710'
  last_name: Wisniewski
- first_name: 'Kim Fung '
  full_name: 'Man, Kim Fung '
  last_name: Man
- first_name: 'Thilo '
  full_name: 'Sauter, Thilo '
  last_name: Sauter
- first_name: 'Lucia '
  full_name: 'Seno, Lucia '
  last_name: Seno
- first_name: Henning
  full_name: Trsek, Henning
  id: '1486'
  last_name: Trsek
  orcid: 0000-0002-0133-0656
- first_name: 'Valeriy '
  full_name: 'Vyatkin, Valeriy '
  last_name: Vyatkin
keyword:
- multimodal sensing
- crystalline materials
- microstructure
- rotation measurement
- PCA
- calorimetry
- pharmaceuticals
- European Pharmacopoeia
language:
- iso: eng
place: '[Piscataway, NJ] '
publication: 2023 IEEE 21st International Conference on Industrial Informatics (INDIN)
publication_identifier:
  eisbn:
  - 978-1-6654-9313-0
  isbn:
  - 978-1-6654-9314-7
publication_status: published
publisher: IEEE
quality_controlled: '1'
status: public
title: A Novel Spectroscopic Approach for Vaseline Quality Discrimination
type: conference_editor_article
user_id: '83781'
year: '2023'
...