---
_id: '13233'
abstract:
- lang: eng
  text: 'Atranones are secondary metabolites produced by Stachybotrys chartarum, a
    mold frequently found in water-damaged indoor environments. In contrast to the
    well-characterized and highly toxic macrocyclic trichothecenes, atranones have
    received relatively limited scientific attention. Approximately 60% of S. chartarum
    isolates from indoor environments produce atranones, while 40% form macrocyclic
    trichothecenes. No strain has been shown to produce both, indicating that the
    biosynthetic pathways for these two mycotoxin classes are mutually exclusive.
    Atranones are dolabellane-like diterpenoids synthesized from geranylgeranyl pyrophosphate
    through multiple enzymatic steps encoded by a specific core gene cluster. While
    the genetic structure of this cluster has been elucidated, its regulatory mechanisms
    remain poorly understood. Notably, although atranone-producing S. chartarum strains
    have been isolated from indoor settings, no study has yet confirmed the actual
    production of atranones in indoor environments, leaving the question of real-world
    exposure unresolved. Experimental studies in cell cultures and animal models indicate
    that atranones possess pro-inflammatory and cytotoxic properties, including the
    induction of apoptosis and cell cycle arrest. Atranone Q has demonstrated antitumor
    activity against osteosarcoma cells in vitro, and more recently identified derivatives
    such as stachatranone and stachybatranone have shown preliminary cardioprotective
    effects under ischemic conditions. However, these pharmacological effects remain
    exploratory and require further validation in in vivo models. Major knowledge
    gaps concern the environmental triggers for atranone biosynthesis, their regulation,
    actual presence in built environments, and potential health risks. These areas
    represent key priorities for future research. '
author:
- first_name: Mareike
  full_name: Dabisch-Ruthe, Mareike
  id: '66516'
  last_name: Dabisch-Ruthe
  orcid: https://orcid.org/0009-0008-7644-0826
- first_name: Jens
  full_name: Pfannebecker, Jens
  id: '45690'
  last_name: Pfannebecker
  orcid: 0009-0005-4133-5442
- first_name: Reinhard K.
  full_name: Straubinger, Reinhard K.
  last_name: Straubinger
- first_name: Frank
  full_name: Ebel, Frank
  last_name: Ebel
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
citation:
  ama: Dabisch-Ruthe M, Pfannebecker J, Straubinger RK, Ebel F, Ulrich S. Atranone-an
    underestimated secondary metabolite? <i>Mycotoxin Research</i>. Published online
    2025. doi:<a href="https://doi.org/10.1007/s12550-025-00609-x">10.1007/s12550-025-00609-x</a>
  apa: Dabisch-Ruthe, M., Pfannebecker, J., Straubinger, R. K., Ebel, F., &#38; Ulrich,
    S. (2025). Atranone-an underestimated secondary metabolite? <i>Mycotoxin Research</i>.
    <a href="https://doi.org/10.1007/s12550-025-00609-x">https://doi.org/10.1007/s12550-025-00609-x</a>
  bjps: <b>Dabisch-Ruthe M <i>et al.</i></b> (2025) Atranone-an Underestimated Secondary
    Metabolite? <i>Mycotoxin Research</i>.
  chicago: Dabisch-Ruthe, Mareike, Jens Pfannebecker, Reinhard K. Straubinger, Frank
    Ebel, and Sebastian Ulrich. “Atranone-an Underestimated Secondary Metabolite?”
    <i>Mycotoxin Research</i>, 2025. <a href="https://doi.org/10.1007/s12550-025-00609-x">https://doi.org/10.1007/s12550-025-00609-x</a>.
  chicago-de: Dabisch-Ruthe, Mareike, Jens Pfannebecker, Reinhard K. Straubinger,
    Frank Ebel und Sebastian Ulrich. 2025. Atranone-an underestimated secondary metabolite?
    <i>Mycotoxin Research</i>. doi:<a href="https://doi.org/10.1007/s12550-025-00609-x">10.1007/s12550-025-00609-x</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Dabisch-Ruthe, Mareike</span>
    ; <span style="font-variant:small-caps;">Pfannebecker, Jens</span> ; <span style="font-variant:small-caps;">Straubinger,
    Reinhard K.</span> ; <span style="font-variant:small-caps;">Ebel, Frank</span>
    ; <span style="font-variant:small-caps;">Ulrich, Sebastian</span>: Atranone-an
    underestimated secondary metabolite? In: <i>Mycotoxin Research</i>. Berlin ; Heidelberg,
    Springer (2025)'
  havard: M. Dabisch-Ruthe, J. Pfannebecker, R.K. Straubinger, F. Ebel, S. Ulrich,
    Atranone-an underestimated secondary metabolite?, Mycotoxin Research. (2025).
  ieee: 'M. Dabisch-Ruthe, J. Pfannebecker, R. K. Straubinger, F. Ebel, and S. Ulrich,
    “Atranone-an underestimated secondary metabolite?,” <i>Mycotoxin Research</i>,
    2025, doi: <a href="https://doi.org/10.1007/s12550-025-00609-x">10.1007/s12550-025-00609-x</a>.'
  mla: Dabisch-Ruthe, Mareike, et al. “Atranone-an Underestimated Secondary Metabolite?”
    <i>Mycotoxin Research</i>, 2025, <a href="https://doi.org/10.1007/s12550-025-00609-x">https://doi.org/10.1007/s12550-025-00609-x</a>.
  short: M. Dabisch-Ruthe, J. Pfannebecker, R.K. Straubinger, F. Ebel, S. Ulrich,
    Mycotoxin Research (2025).
  ufg: '<b>Dabisch-Ruthe, Mareike u. a.</b>: Atranone-an underestimated secondary
    metabolite?, in: <i>Mycotoxin Research</i> (2025).'
  van: Dabisch-Ruthe M, Pfannebecker J, Straubinger RK, Ebel F, Ulrich S. Atranone-an
    underestimated secondary metabolite? Mycotoxin Research. 2025;
date_created: 2025-10-01T09:20:35Z
date_updated: 2025-10-06T12:11:00Z
department:
- _id: DEP4010
doi: 10.1007/s12550-025-00609-x
keyword:
- Atranone
- Secondary metabolite
- Stachybotrys
- Stachatranone
- Stachybatranone
language:
- iso: eng
place: Berlin ; Heidelberg
publication: Mycotoxin Research
publication_identifier:
  eissn:
  - 1867-1632
  issn:
  - 0178-7888
publication_status: published
publisher: Springer
status: public
title: Atranone-an underestimated secondary metabolite?
type: scientific_journal_article
user_id: '83781'
year: '2025'
...
---
_id: '12945'
abstract:
- lang: eng
  text: Stachybotrys chartarum is a toxigenic fungus that is frequently isolated from
    damp building materials or improperly stored forage. Macrocyclic trichothecenes
    and in particular satratoxins are the most potent mycotoxins known to be produced
    by this fungus. Exposure of humans or animals to these secondary metabolites can
    be associated with severe health problems. To assess the pathogenic potential
    of S. chartarum isolates, it is essential to cultivate them under conditions that
    reliably promote toxin production. Potato dextrose agar (PDA) was reported to
    be the optimal nutrition medium for satratoxin production. In this study, the
    growth of S. chartarum genotype S strains on PDA from two manufacturers led to
    divergent results, namely, well-grown and sporulating cultures with high satratoxin
    concentrations (20.8 ± 0.4 µg/cm2) versus cultures with sparse sporulation and
    low satratoxin production (0.3 ± 0.1 µg/cm2). This finding is important for any
    attempt to identify toxigenic S. chartarum isolates. Further experiments performed
    with the two media provided strong evidence for a link between satratoxin production
    and sporulation. A comparison of three-point and one-point cultures grown on the
    two types of PDA, furthermore, demonstrated an inter-colony communication that
    influences both sporulation and mycotoxin production of S. chartarum genotype
    S strains.
article_number: '515'
author:
- first_name: Katharina
  full_name: Tribelhorn, Katharina
  last_name: Tribelhorn
- first_name: Magdalena
  full_name: Twarużek, Magdalena
  last_name: Twarużek
- first_name: Ewelina
  full_name: Soszczyńska, Ewelina
  last_name: Soszczyńska
- first_name: Jörg
  full_name: Rau, Jörg
  last_name: Rau
- first_name: Christiane
  full_name: Baschien, Christiane
  last_name: Baschien
- first_name: Reinhard K.
  full_name: Straubinger, Reinhard K.
  last_name: Straubinger
- first_name: Frank
  full_name: Ebel, Frank
  last_name: Ebel
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
citation:
  ama: Tribelhorn K, Twarużek M, Soszczyńska E, et al. Production of Satratoxin G
    and H Is Tightly Linked to Sporulation in Stachybotrys chartarum. <i>Toxins</i>.
    2022;14(8). doi:<a href="https://doi.org/10.3390/toxins14080515">10.3390/toxins14080515</a>
  apa: Tribelhorn, K., Twarużek, M., Soszczyńska, E., Rau, J., Baschien, C., Straubinger,
    R. K., Ebel, F., &#38; Ulrich, S. (2022). Production of Satratoxin G and H Is
    Tightly Linked to Sporulation in Stachybotrys chartarum. <i>Toxins</i>, <i>14</i>(8),
    Article 515. <a href="https://doi.org/10.3390/toxins14080515">https://doi.org/10.3390/toxins14080515</a>
  bjps: <b>Tribelhorn K <i>et al.</i></b> (2022) Production of Satratoxin G and H
    Is Tightly Linked to Sporulation in Stachybotrys Chartarum. <i>Toxins</i> <b>14</b>.
  chicago: Tribelhorn, Katharina, Magdalena Twarużek, Ewelina Soszczyńska, Jörg Rau,
    Christiane Baschien, Reinhard K. Straubinger, Frank Ebel, and Sebastian Ulrich.
    “Production of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys
    Chartarum.” <i>Toxins</i> 14, no. 8 (2022). <a href="https://doi.org/10.3390/toxins14080515">https://doi.org/10.3390/toxins14080515</a>.
  chicago-de: Tribelhorn, Katharina, Magdalena Twarużek, Ewelina Soszczyńska, Jörg
    Rau, Christiane Baschien, Reinhard K. Straubinger, Frank Ebel und Sebastian Ulrich.
    2022. Production of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys
    chartarum. <i>Toxins</i> 14, Nr. 8. doi:<a href="https://doi.org/10.3390/toxins14080515">10.3390/toxins14080515</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Tribelhorn, Katharina</span>
    ; <span style="font-variant:small-caps;">Twarużek, Magdalena</span> ; <span style="font-variant:small-caps;">Soszczyńska,
    Ewelina</span> ; <span style="font-variant:small-caps;">Rau, Jörg</span> ; <span
    style="font-variant:small-caps;">Baschien, Christiane</span> ; <span style="font-variant:small-caps;">Straubinger,
    Reinhard K.</span> ; <span style="font-variant:small-caps;">Ebel, Frank</span>
    ; <span style="font-variant:small-caps;">Ulrich, Sebastian</span>: Production
    of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys chartarum.
    In: <i>Toxins</i> Bd. 14, MDPI (2022), Nr. 8'
  havard: K. Tribelhorn, M. Twarużek, E. Soszczyńska, J. Rau, C. Baschien, R.K. Straubinger,
    F. Ebel, S. Ulrich, Production of Satratoxin G and H Is Tightly Linked to Sporulation
    in Stachybotrys chartarum, Toxins. 14 (2022).
  ieee: 'K. Tribelhorn <i>et al.</i>, “Production of Satratoxin G and H Is Tightly
    Linked to Sporulation in Stachybotrys chartarum,” <i>Toxins</i>, vol. 14, no.
    8, Art. no. 515, 2022, doi: <a href="https://doi.org/10.3390/toxins14080515">10.3390/toxins14080515</a>.'
  mla: Tribelhorn, Katharina, et al. “Production of Satratoxin G and H Is Tightly
    Linked to Sporulation in Stachybotrys Chartarum.” <i>Toxins</i>, vol. 14, no.
    8, 515, 2022, <a href="https://doi.org/10.3390/toxins14080515">https://doi.org/10.3390/toxins14080515</a>.
  short: K. Tribelhorn, M. Twarużek, E. Soszczyńska, J. Rau, C. Baschien, R.K. Straubinger,
    F. Ebel, S. Ulrich, Toxins 14 (2022).
  ufg: '<b>Tribelhorn, Katharina u. a.</b>: Production of Satratoxin G and H Is Tightly
    Linked to Sporulation in Stachybotrys chartarum, in: <i>Toxins</i> 14 (2022),
    H. 8.'
  van: Tribelhorn K, Twarużek M, Soszczyńska E, Rau J, Baschien C, Straubinger RK,
    et al. Production of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys
    chartarum. Toxins. 2022;14(8).
date_created: 2025-06-15T09:56:06Z
date_updated: 2025-06-16T11:52:01Z
department:
- _id: DEP4010
doi: 10.3390/toxins14080515
extern: '1'
intvolume: '        14'
issue: '8'
keyword:
- Stachybotrys chartarum genotype S
- sporulation
- satratoxins
- macrocyclic trichothecenes
- inter-colony communication
language:
- iso: eng
publication: Toxins
publication_identifier:
  eissn:
  - 2072-6651
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Production of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys
  chartarum
type: scientific_journal_article
user_id: '83781'
volume: 14
year: '2022'
...
---
_id: '12947'
abstract:
- lang: eng
  text: 'Stachybotrys chartarum is frequently isolated from damp building materials
    or improperly stored animal forage. Human and animal exposure to the secondary
    metabolites of this mold is linked to severe health effects. The mutually exclusive
    production of either satratoxins or atranones defines the chemotypes A and S.
    Based upon the genes (satratoxin cluster, SC1-3, sat or atranone cluster, AC1,
    atr) that are supposed to be essential for satratoxin and atranone production,
    S. chartarum can furthermore be divided into three genotypes: the S-type possessing
    all sat- but no atr-genes, the A-type lacking the sat- but harboring all atr-genes,
    and the H-type having only certain sat- and all atr-genes. We analyzed the above-mentioned
    gene clusters and their flanking regions to shed light on the evolutionary relationship.
    Furthermore, we performed a deep re-sequencing and LC-MS/MS (Liquid chromatography–mass
    spectrometry) analysis. We propose a first model for the evolution of the S. chartarum
    genotypes. We assume that genotype H represents the most ancient form. A loss
    of the AC1 and the concomitant acquisition of the SC2 led to the emergence of
    the genotype S. According to our model, the genotype H also developed towards
    genotype A, a process that was accompanied by a loss of SC1 and SC3.'
article_number: '340'
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Katharina
  full_name: Lang, Katharina
  last_name: Lang
- first_name: Ludwig
  full_name: Niessen, Ludwig
  last_name: Niessen
- first_name: Christiane
  full_name: Baschien, Christiane
  last_name: Baschien
- first_name: Robert
  full_name: Kosicki, Robert
  last_name: Kosicki
- first_name: Magdalena
  full_name: Twarużek, Magdalena
  last_name: Twarużek
- first_name: Reinhard K.
  full_name: Straubinger, Reinhard K.
  last_name: Straubinger
- first_name: Frank
  full_name: Ebel, Frank
  last_name: Ebel
citation:
  ama: Ulrich S, Lang K, Niessen L, et al. The Evolution of the Satratoxin and Atranone
    Gene Clusters of Stachybotrys chartarum. <i>Journal of Fungi</i>. 2022;8(4). doi:<a
    href="https://doi.org/10.3390/jof8040340">10.3390/jof8040340</a>
  apa: Ulrich, S., Lang, K., Niessen, L., Baschien, C., Kosicki, R., Twarużek, M.,
    Straubinger, R. K., &#38; Ebel, F. (2022). The Evolution of the Satratoxin and
    Atranone Gene Clusters of Stachybotrys chartarum. <i>Journal of Fungi</i>, <i>8</i>(4),
    Article 340. <a href="https://doi.org/10.3390/jof8040340">https://doi.org/10.3390/jof8040340</a>
  bjps: <b>Ulrich S <i>et al.</i></b> (2022) The Evolution of the Satratoxin and Atranone
    Gene Clusters of Stachybotrys Chartarum. <i>Journal of Fungi</i> <b>8</b>.
  chicago: Ulrich, Sebastian, Katharina Lang, Ludwig Niessen, Christiane Baschien,
    Robert Kosicki, Magdalena Twarużek, Reinhard K. Straubinger, and Frank Ebel. “The
    Evolution of the Satratoxin and Atranone Gene Clusters of Stachybotrys Chartarum.”
    <i>Journal of Fungi</i> 8, no. 4 (2022). <a href="https://doi.org/10.3390/jof8040340">https://doi.org/10.3390/jof8040340</a>.
  chicago-de: Ulrich, Sebastian, Katharina Lang, Ludwig Niessen, Christiane Baschien,
    Robert Kosicki, Magdalena Twarużek, Reinhard K. Straubinger und Frank Ebel. 2022.
    The Evolution of the Satratoxin and Atranone Gene Clusters of Stachybotrys chartarum.
    <i>Journal of Fungi</i> 8, Nr. 4. doi:<a href="https://doi.org/10.3390/jof8040340">10.3390/jof8040340</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Ulrich, Sebastian</span> ;
    <span style="font-variant:small-caps;">Lang, Katharina</span> ; <span style="font-variant:small-caps;">Niessen,
    Ludwig</span> ; <span style="font-variant:small-caps;">Baschien, Christiane</span>
    ; <span style="font-variant:small-caps;">Kosicki, Robert</span> ; <span style="font-variant:small-caps;">Twarużek,
    Magdalena</span> ; <span style="font-variant:small-caps;">Straubinger, Reinhard
    K.</span> ; <span style="font-variant:small-caps;">Ebel, Frank</span>: The Evolution
    of the Satratoxin and Atranone Gene Clusters of Stachybotrys chartarum. In: <i>Journal
    of Fungi</i> Bd. 8, MDPI AG (2022), Nr. 4'
  havard: S. Ulrich, K. Lang, L. Niessen, C. Baschien, R. Kosicki, M. Twarużek, R.K.
    Straubinger, F. Ebel, The Evolution of the Satratoxin and Atranone Gene Clusters
    of Stachybotrys chartarum, Journal of Fungi. 8 (2022).
  ieee: 'S. Ulrich <i>et al.</i>, “The Evolution of the Satratoxin and Atranone Gene
    Clusters of Stachybotrys chartarum,” <i>Journal of Fungi</i>, vol. 8, no. 4, Art.
    no. 340, 2022, doi: <a href="https://doi.org/10.3390/jof8040340">10.3390/jof8040340</a>.'
  mla: Ulrich, Sebastian, et al. “The Evolution of the Satratoxin and Atranone Gene
    Clusters of Stachybotrys Chartarum.” <i>Journal of Fungi</i>, vol. 8, no. 4, 340,
    2022, <a href="https://doi.org/10.3390/jof8040340">https://doi.org/10.3390/jof8040340</a>.
  short: S. Ulrich, K. Lang, L. Niessen, C. Baschien, R. Kosicki, M. Twarużek, R.K.
    Straubinger, F. Ebel, Journal of Fungi 8 (2022).
  ufg: '<b>Ulrich, Sebastian u. a.</b>: The Evolution of the Satratoxin and Atranone
    Gene Clusters of Stachybotrys chartarum, in: <i>Journal of Fungi</i> 8 (2022),
    H. 4.'
  van: Ulrich S, Lang K, Niessen L, Baschien C, Kosicki R, Twarużek M, et al. The
    Evolution of the Satratoxin and Atranone Gene Clusters of Stachybotrys chartarum.
    Journal of Fungi. 2022;8(4).
date_created: 2025-06-15T09:57:20Z
date_updated: 2025-06-16T11:59:52Z
department:
- _id: DEP4010
doi: 10.3390/jof8040340
extern: '1'
intvolume: '         8'
issue: '4'
keyword:
- Stachybotrys
- genome
- macrocyclic trichothecene
- atranone
language:
- iso: eng
publication: Journal of Fungi
publication_identifier:
  eissn:
  - 2309-608X
publication_status: published
publisher: MDPI AG
quality_controlled: '1'
status: public
title: The Evolution of the Satratoxin and Atranone Gene Clusters of Stachybotrys
  chartarum
type: scientific_journal_article
user_id: '83781'
volume: 8
year: '2022'
...
---
_id: '12952'
abstract:
- lang: eng
  text: 'Straw is the main by-product of grain production, used as bedding material
    and animal feed. If produced or stored under adverse hygienic conditions, straw
    is prone to the growth of filamentous fungi. Some of them, e.g. Aspergillus, Fusarium
    and Stachybotrys spp. are well-known mycotoxin producers. Since studies on mycotoxins
    in straw are scarce, 192 straw samples (wheat n = 80; barley n = 79; triticale
    n = 12; oat n = 11; rye n = 12) were collected across Germany within the German
    official feed surveillance and screened for the presence of 21 mycotoxins. The
    following mycotoxins (positive samples for at least one mycotoxin n = 184) were
    detected: zearalenone (n = 86, 6.0–785 μg/kg), nivalenol (n = 51, 30–2,600 μg/kg),
    deoxynivalenol (n = 156, 20–24,000 μg/kg), 15-acetyl-deoxynivalenol (n = 34, 20–2,400
    μg/kg), 3-acetyl-deoxynivalenol (n = 16, 40–340 μg/kg), scirpentriol (n = 14,
    40–680 μg/kg), T-2 toxin (n = 67, 10–250 μg/kg), HT-2 toxin (n = 92, 20–800 μg/kg),
    T-2 tetraol (n = 13, 70–480 μg/kg). 15-monoacetoxyscirpenol (30 μg/kg) and T-2
    triol (60 μg/kg) were only detected in one barley sample. Macrocyclic trichothecenes
    (satratoxin G, F, roridin E, and verrucarin J) were also found in only one barley
    sample (quantified as roridin A equivalent: total 183 μg/kg). The occurrence of
    stachybotrylactam was monitored for the first time in four samples (n = 4, 0.96–7.4
    μg/kg). Fusarenon-X, 4,15-diacetoxyscirpenol, neosolaniol, satratoxin H and roridin-L2
    were not detectable in the samples. The results indicate a non-negligible contribution
    of straw to oral and possibly inhalation exposure to mycotoxins of animals or
    humans handling contaminated straw.'
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Christoph
  full_name: Gottschalk, Christoph
  last_name: Gottschalk
- first_name: Barbara
  full_name: Biermaier, Barbara
  last_name: Biermaier
- first_name: Eunike
  full_name: Bahlinger, Eunike
  last_name: Bahlinger
- first_name: Magdalena
  full_name: Twarużek, Magdalena
  last_name: Twarużek
- first_name: Sarah
  full_name: Asmussen, Sarah
  last_name: Asmussen
- first_name: Margit
  full_name: Schollenberger, Margit
  last_name: Schollenberger
- first_name: Hana
  full_name: Valenta, Hana
  last_name: Valenta
- first_name: Frank
  full_name: Ebel, Frank
  last_name: Ebel
- first_name: Sven
  full_name: Dänicke, Sven
  last_name: Dänicke
citation:
  ama: Ulrich S, Gottschalk C, Biermaier B, et al. Occurrence of type A, B and D trichothecenes,
    zearalenone and stachybotrylactam in straw. <i>Archives of animal nutrition =
    Archiv für Tierernährung</i>. 2021;75(2):105-120. doi:<a href="https://doi.org/10.1080/1745039x.2021.1877075">10.1080/1745039x.2021.1877075</a>
  apa: Ulrich, S., Gottschalk, C., Biermaier, B., Bahlinger, E., Twarużek, M., Asmussen,
    S., Schollenberger, M., Valenta, H., Ebel, F., &#38; Dänicke, S. (2021). Occurrence
    of type A, B and D trichothecenes, zearalenone and stachybotrylactam in straw.
    <i>Archives of Animal Nutrition = Archiv Für Tierernährung</i>, <i>75</i>(2),
    105–120. <a href="https://doi.org/10.1080/1745039x.2021.1877075">https://doi.org/10.1080/1745039x.2021.1877075</a>
  bjps: <b>Ulrich S <i>et al.</i></b> (2021) Occurrence of Type A, B and D Trichothecenes,
    Zearalenone and Stachybotrylactam in Straw. <i>Archives of animal nutrition =
    Archiv für Tierernährung</i> <b>75</b>, 105–120.
  chicago: 'Ulrich, Sebastian, Christoph Gottschalk, Barbara Biermaier, Eunike Bahlinger,
    Magdalena Twarużek, Sarah Asmussen, Margit Schollenberger, Hana Valenta, Frank
    Ebel, and Sven Dänicke. “Occurrence of Type A, B and D Trichothecenes, Zearalenone
    and Stachybotrylactam in Straw.” <i>Archives of Animal Nutrition = Archiv Für
    Tierernährung</i> 75, no. 2 (2021): 105–20. <a href="https://doi.org/10.1080/1745039x.2021.1877075">https://doi.org/10.1080/1745039x.2021.1877075</a>.'
  chicago-de: 'Ulrich, Sebastian, Christoph Gottschalk, Barbara Biermaier, Eunike
    Bahlinger, Magdalena Twarużek, Sarah Asmussen, Margit Schollenberger, Hana Valenta,
    Frank Ebel und Sven Dänicke. 2021. Occurrence of type A, B and D trichothecenes,
    zearalenone and stachybotrylactam in straw. <i>Archives of animal nutrition =
    Archiv für Tierernährung</i> 75, Nr. 2: 105–120. doi:<a href="https://doi.org/10.1080/1745039x.2021.1877075">10.1080/1745039x.2021.1877075</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;"><span style="font-variant:small-caps;">Ulrich,
    Sebastian</span> ; <span style="font-variant:small-caps;">Gottschalk, Christoph</span>
    ; <span style="font-variant:small-caps;">Biermaier, Barbara</span> ; <span style="font-variant:small-caps;">Bahlinger,
    Eunike</span> ; <span style="font-variant:small-caps;">Twarużek, Magdalena</span>
    ; <span style="font-variant:small-caps;">Asmussen, Sarah</span> ; <span style="font-variant:small-caps;">Schollenberger,
    Margit</span> ; <span style="font-variant:small-caps;">Valenta, Hana</span> ;
    u. a.</span>: Occurrence of type A, B and D trichothecenes, zearalenone and stachybotrylactam
    in straw. In: <i>Archives of animal nutrition = Archiv für Tierernährung</i> Bd.
    75. Abingdon , Taylor &#38; Francis  (2021), Nr. 2, S. 105–120'
  havard: S. Ulrich, C. Gottschalk, B. Biermaier, E. Bahlinger, M. Twarużek, S. Asmussen,
    M. Schollenberger, H. Valenta, F. Ebel, S. Dänicke, Occurrence of type A, B and
    D trichothecenes, zearalenone and stachybotrylactam in straw, Archives of Animal
    Nutrition = Archiv Für Tierernährung. 75 (2021) 105–120.
  ieee: 'S. Ulrich <i>et al.</i>, “Occurrence of type A, B and D trichothecenes, zearalenone
    and stachybotrylactam in straw,” <i>Archives of animal nutrition = Archiv für
    Tierernährung</i>, vol. 75, no. 2, pp. 105–120, 2021, doi: <a href="https://doi.org/10.1080/1745039x.2021.1877075">10.1080/1745039x.2021.1877075</a>.'
  mla: Ulrich, Sebastian, et al. “Occurrence of Type A, B and D Trichothecenes, Zearalenone
    and Stachybotrylactam in Straw.” <i>Archives of Animal Nutrition = Archiv Für
    Tierernährung</i>, vol. 75, no. 2, 2021, pp. 105–20, <a href="https://doi.org/10.1080/1745039x.2021.1877075">https://doi.org/10.1080/1745039x.2021.1877075</a>.
  short: S. Ulrich, C. Gottschalk, B. Biermaier, E. Bahlinger, M. Twarużek, S. Asmussen,
    M. Schollenberger, H. Valenta, F. Ebel, S. Dänicke, Archives of Animal Nutrition
    = Archiv Für Tierernährung 75 (2021) 105–120.
  ufg: '<b>Ulrich, Sebastian u. a.</b>: Occurrence of type A, B and D trichothecenes,
    zearalenone and stachybotrylactam in straw, in: <i>Archives of animal nutrition
    = Archiv für Tierernährung</i> 75 (2021), H. 2,  S. 105–120.'
  van: Ulrich S, Gottschalk C, Biermaier B, Bahlinger E, Twarużek M, Asmussen S, et
    al. Occurrence of type A, B and D trichothecenes, zearalenone and stachybotrylactam
    in straw. Archives of animal nutrition = Archiv für Tierernährung. 2021;75(2):105–20.
date_created: 2025-06-15T09:59:54Z
date_updated: 2025-06-16T12:25:24Z
department:
- _id: DEP4010
doi: 10.1080/1745039x.2021.1877075
extern: '1'
intvolume: '        75'
issue: '2'
keyword:
- Fusarium
- mycotoxins
- stachybotrylactam
- stachybotrys
- straw
- trichothecenes
- zearalenone
language:
- iso: eng
page: 105-120
place: 'Abingdon '
publication: Archives of animal nutrition = Archiv für Tierernährung
publication_identifier:
  eissn:
  - 1477-2817
  issn:
  - 1745-039X
publication_status: published
publisher: 'Taylor & Francis '
quality_controlled: '1'
status: public
title: Occurrence of type A, B and D trichothecenes, zearalenone and stachybotrylactam
  in straw
type: scientific_journal_article
user_id: '83781'
volume: 75
year: '2021'
...
---
_id: '12956'
abstract:
- lang: eng
  text: Stachybotrys (S.) chartarum had been linked to severe health problems in humans
    and animals, which occur after exposure to the toxic secondary metabolites of
    this mold. S. chartarum had been isolated from different environmental sources,
    ranging from culinary herbs and improperly stored fodder to damp building materials.
    To access the pathogenic potential of isolates, it is essential to analyze them
    under defined conditions that allow for the production of their toxic metabolites.
    All Stachybotrys species are assumed to produce the immunosuppressive phenylspirodrimanes,
    but the highly cytotoxic macrocyclic trichothecenes are exclusively generated
    by the genotype S of S. chartarum. In this study, we have analyzed four genotype
    S strains initially isolated from three different habitats. We grew them on five
    commonly used media (malt-extract-agar, glucose-yeast-peptone-agar, potato-dextrose-agar,
    cellulose-agar, Sabouraud-dextrose-agar) to identify conditions that promote mycotoxin
    production. Using LC-MS/MS, we have quantified stachybotrylactam and all S-type
    specific macrocyclic trichothecenes (satratoxin G, H, F, roridin E, L-2, verrucarin
    J). All five media supported a comparable fungal growth and sporulation at 25
    °C in the dark. The highest concentrations of macrocyclic trichothecenes were
    detected on potato-dextrose-agar or cellulose-agar. Malt-extract-agar let to an
    intermediate and glucose-yeast-peptone-agar and Sabouraud-dextrose-agar to a poor
    mycotoxin production. These data demonstrate that the mycotoxin production clearly
    depends on the composition of the respective medium. Our findings provide a starting
    point for further studies in order to identify individual components that either
    support or repress the production of mycotoxins in S. chartarum.
article_number: '159'
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Cornelius
  full_name: Schäfer, Cornelius
  last_name: Schäfer
citation:
  ama: Ulrich S, Schäfer C. Toxin Production by Stachybotrys chartarum Genotype S
    on Different Culture Media. <i>Journal of Fungi</i>. 2020;6(3). doi:<a href="https://doi.org/10.3390/jof6030159">10.3390/jof6030159</a>
  apa: Ulrich, S., &#38; Schäfer, C. (2020). Toxin Production by Stachybotrys chartarum
    Genotype S on Different Culture Media. <i>Journal of Fungi</i>, <i>6</i>(3), Article
    159. <a href="https://doi.org/10.3390/jof6030159">https://doi.org/10.3390/jof6030159</a>
  bjps: <b>Ulrich S and Schäfer C</b> (2020) Toxin Production by Stachybotrys Chartarum
    Genotype S on Different Culture Media. <i>Journal of Fungi</i> <b>6</b>.
  chicago: Ulrich, Sebastian, and Cornelius Schäfer. “Toxin Production by Stachybotrys
    Chartarum Genotype S on Different Culture Media.” <i>Journal of Fungi</i> 6, no.
    3 (2020). <a href="https://doi.org/10.3390/jof6030159">https://doi.org/10.3390/jof6030159</a>.
  chicago-de: Ulrich, Sebastian und Cornelius Schäfer. 2020. Toxin Production by Stachybotrys
    chartarum Genotype S on Different Culture Media. <i>Journal of Fungi</i> 6, Nr.
    3. doi:<a href="https://doi.org/10.3390/jof6030159">10.3390/jof6030159</a>, .
  din1505-2-1: '<span style="font-variant:small-caps;">Ulrich, Sebastian</span> ;
    <span style="font-variant:small-caps;">Schäfer, Cornelius</span>: Toxin Production
    by Stachybotrys chartarum Genotype S on Different Culture Media. In: <i>Journal
    of Fungi</i> Bd. 6. Basel, MDPI  (2020), Nr. 3'
  havard: S. Ulrich, C. Schäfer, Toxin Production by Stachybotrys chartarum Genotype
    S on Different Culture Media, Journal of Fungi. 6 (2020).
  ieee: 'S. Ulrich and C. Schäfer, “Toxin Production by Stachybotrys chartarum Genotype
    S on Different Culture Media,” <i>Journal of Fungi</i>, vol. 6, no. 3, Art. no.
    159, 2020, doi: <a href="https://doi.org/10.3390/jof6030159">10.3390/jof6030159</a>.'
  mla: Ulrich, Sebastian, and Cornelius Schäfer. “Toxin Production by Stachybotrys
    Chartarum Genotype S on Different Culture Media.” <i>Journal of Fungi</i>, vol.
    6, no. 3, 159, 2020, <a href="https://doi.org/10.3390/jof6030159">https://doi.org/10.3390/jof6030159</a>.
  short: S. Ulrich, C. Schäfer, Journal of Fungi 6 (2020).
  ufg: '<b>Ulrich, Sebastian/Schäfer, Cornelius</b>: Toxin Production by Stachybotrys
    chartarum Genotype S on Different Culture Media, in: <i>Journal of Fungi</i> 6
    (2020), H. 3.'
  van: Ulrich S, Schäfer C. Toxin Production by Stachybotrys chartarum Genotype S
    on Different Culture Media. Journal of Fungi. 2020;6(3).
date_created: 2025-06-15T10:01:42Z
date_updated: 2025-06-16T13:59:56Z
department:
- _id: DEP4010
doi: 10.3390/jof6030159
extern: '1'
intvolume: '         6'
issue: '3'
keyword:
- Stachybotrys
- genotype
- macrocyclic trichothecenes
- stachybotrylactam
language:
- iso: eng
place: Basel
publication: Journal of Fungi
publication_identifier:
  eissn:
  - 2309-608X
publication_status: published
publisher: 'MDPI '
quality_controlled: '1'
status: public
title: Toxin Production by Stachybotrys chartarum Genotype S on Different Culture
  Media
type: scientific_journal_article
user_id: '83781'
volume: 6
year: '2020'
...
---
_id: '12971'
abstract:
- lang: eng
  text: The genus Stachybotrys produces a broad diversity of secondary metabolites,
    including macrocyclic trichothecenes, atranones, and phenylspirodrimanes. Although
    the class of the phenylspirodrimanes is the major one and consists of a multitude
    of metabolites bearing various structural modifications, few investigations have
    been carried out. Thus, the presented study deals with the quantitative determination
    of several secondary metabolites produced by distinct Stachybotrys species for
    comparison of their metabolite profiles. For that purpose, 15 of the primarily
    produced secondary metabolites were isolated from fungal cultures and structurally
    characterized in order to be used as analytical standards for the development
    of an LC-MS/MS multimethod. The developed method was applied to the analysis of
    micro-scale extracts from 5 different Stachybotrys strains, which were cultured
    on different media. In that process, spontaneous dialdehyde/lactone isomerization
    was observed for some of the isolated secondary metabolites, and novel stachybotrychromenes
    were quantitatively investigated for the first time. The metabolite profiles of
    Stachybotrys species are considerably influenced by time of growth and substrate
    availability, as well as the individual biosynthetic potential of the respective
    species. Regarding the reported adverse effects associated with Stachybotrys growth
    in building environments, combinatory effects of the investigated secondary metabolites
    should be addressed and the role of the phenylspirodrimanes re-evaluated in future
    research.
article_number: '133'
author:
- first_name: Annika
  full_name: Jagels, Annika
  last_name: Jagels
- first_name: Viktoria
  full_name: Lindemann, Viktoria
  last_name: Lindemann
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Christoph
  full_name: Gottschalk, Christoph
  last_name: Gottschalk
- first_name: Benedikt
  full_name: Cramer, Benedikt
  last_name: Cramer
- first_name: Florian
  full_name: Hübner, Florian
  last_name: Hübner
- first_name: Manfred
  full_name: Gareis, Manfred
  last_name: Gareis
- first_name: Hans-Ulrich
  full_name: Humpf, Hans-Ulrich
  last_name: Humpf
citation:
  ama: Jagels A, Lindemann V, Ulrich S, et al. Exploring Secondary Metabolite Profiles
    of Stachybotrys spp. by LC-MS/MS. <i>Toxins</i>. 2019;11(3). doi:<a href="https://doi.org/10.3390/toxins11030133">10.3390/toxins11030133</a>
  apa: Jagels, A., Lindemann, V., Ulrich, S., Gottschalk, C., Cramer, B., Hübner,
    F., Gareis, M., &#38; Humpf, H.-U. (2019). Exploring Secondary Metabolite Profiles
    of Stachybotrys spp. by LC-MS/MS. <i>Toxins</i>, <i>11</i>(3), Article 133. <a
    href="https://doi.org/10.3390/toxins11030133">https://doi.org/10.3390/toxins11030133</a>
  bjps: <b>Jagels A <i>et al.</i></b> (2019) Exploring Secondary Metabolite Profiles
    of Stachybotrys Spp. by LC-MS/MS. <i>Toxins</i> <b>11</b>.
  chicago: Jagels, Annika, Viktoria Lindemann, Sebastian Ulrich, Christoph Gottschalk,
    Benedikt Cramer, Florian Hübner, Manfred Gareis, and Hans-Ulrich Humpf. “Exploring
    Secondary Metabolite Profiles of Stachybotrys Spp. by LC-MS/MS.” <i>Toxins</i>
    11, no. 3 (2019). <a href="https://doi.org/10.3390/toxins11030133">https://doi.org/10.3390/toxins11030133</a>.
  chicago-de: Jagels, Annika, Viktoria Lindemann, Sebastian Ulrich, Christoph Gottschalk,
    Benedikt Cramer, Florian Hübner, Manfred Gareis und Hans-Ulrich Humpf. 2019. Exploring
    Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS. <i>Toxins</i>
    11, Nr. 3. doi:<a href="https://doi.org/10.3390/toxins11030133">10.3390/toxins11030133</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Jagels, Annika</span> ; <span
    style="font-variant:small-caps;">Lindemann, Viktoria</span> ; <span style="font-variant:small-caps;">Ulrich,
    Sebastian</span> ; <span style="font-variant:small-caps;">Gottschalk, Christoph</span>
    ; <span style="font-variant:small-caps;">Cramer, Benedikt</span> ; <span style="font-variant:small-caps;">Hübner,
    Florian</span> ; <span style="font-variant:small-caps;">Gareis, Manfred</span>
    ; <span style="font-variant:small-caps;">Humpf, Hans-Ulrich</span>: Exploring
    Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS. In: <i>Toxins</i>
    Bd. 11. Basel, MDPI (2019), Nr. 3'
  havard: A. Jagels, V. Lindemann, S. Ulrich, C. Gottschalk, B. Cramer, F. Hübner,
    M. Gareis, H.-U. Humpf, Exploring Secondary Metabolite Profiles of Stachybotrys
    spp. by LC-MS/MS, Toxins. 11 (2019).
  ieee: 'A. Jagels <i>et al.</i>, “Exploring Secondary Metabolite Profiles of Stachybotrys
    spp. by LC-MS/MS,” <i>Toxins</i>, vol. 11, no. 3, Art. no. 133, 2019, doi: <a
    href="https://doi.org/10.3390/toxins11030133">10.3390/toxins11030133</a>.'
  mla: Jagels, Annika, et al. “Exploring Secondary Metabolite Profiles of Stachybotrys
    Spp. by LC-MS/MS.” <i>Toxins</i>, vol. 11, no. 3, 133, 2019, <a href="https://doi.org/10.3390/toxins11030133">https://doi.org/10.3390/toxins11030133</a>.
  short: A. Jagels, V. Lindemann, S. Ulrich, C. Gottschalk, B. Cramer, F. Hübner,
    M. Gareis, H.-U. Humpf, Toxins 11 (2019).
  ufg: '<b>Jagels, Annika u. a.</b>: Exploring Secondary Metabolite Profiles of Stachybotrys
    spp. by LC-MS/MS, in: <i>Toxins</i> 11 (2019), H. 3.'
  van: Jagels A, Lindemann V, Ulrich S, Gottschalk C, Cramer B, Hübner F, et al. Exploring
    Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS. Toxins. 2019;11(3).
date_created: 2025-06-15T10:23:36Z
date_updated: 2025-06-17T14:12:55Z
department:
- _id: DEP4010
doi: 10.3390/toxins11030133
extern: '1'
intvolume: '        11'
issue: '3'
keyword:
- Stachybotrys spp.
- metabolite profiles
- LC-MS/MS
- satratoxins
- phenylspirodrimanes
- stachybotrychromenes
- biosynthetic production
language:
- iso: eng
place: Basel
publication: Toxins
publication_identifier:
  eissn:
  - 2072-6651
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Exploring Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS
type: scientific_journal_article
user_id: '83781'
volume: 11
year: '2019'
...
---
_id: '12977'
abstract:
- lang: eng
  text: 'Stachybotrys (S.) spp. are omnipresent cellulolytic molds. Some species are
    highly toxic owing to their ability to synthesize various secondary metabolites
    such as macrocyclic trichothecenes or hemolysins. The reliable identification
    of Stachybotrys at species level is currently limited to genome-based identification.
    This study aimed to establish a fast and reliable MALDI-TOF MS identification
    method by optimizing the pre-analytical steps for protein extraction for subsequent
    generation of high-quality fingerprint mass spectra. Eight reference strains of
    the American Type Culture Collection and the Technical University of Denmark were
    cultivated in triplicate (biological repetitions) for 2 days in malt extract broth.
    The mycelia (1.5 ml) were first washed with 75 % ethanol and an additional washing
    step with dimethyl sulfoxide (10 %) was added to remove unspecific low weight
    masses. Furthermore, mycelia were broken with roughened glass beads in formic
    acid (70 %) and acetonitrile. The method was successfully applied to a total of
    45 isolates of Stachybotrys originating from three different habitats (indoor,
    feed, and food samples; n = 15 each): Twenty-seven isolates of S. chartarum and
    18 isolates of S. chlorohalonata could be identified by MALDI-TOF MS. The data
    obtained exactly matched those obtained by genome-based identification. The mean
    score values for S. chartarum ranged from 2.509 to 2.739 and from 2.148 to 2.622
    for S. chlorohalonata with a very good reproducibility: the relative standard
    deviations were between 0.3 % and 6.8 %. Thus, MALDI-TOF MS proved to be a fast
    and reliable alternative to identification of Stachybotrys spp. by nucleotide
    amplification and sequencing.'
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Barbara
  full_name: Biermaier, Barbara
  last_name: Biermaier
- first_name: Oliver
  full_name: Bader, Oliver
  last_name: Bader
- first_name: Georg
  full_name: Wolf, Georg
  last_name: Wolf
- first_name: Reinhard K.
  full_name: Straubinger, Reinhard K.
  last_name: Straubinger
- first_name: Andrea
  full_name: Didier, Andrea
  last_name: Didier
- first_name: Brigitte
  full_name: Sperner, Brigitte
  last_name: Sperner
- first_name: Karin
  full_name: Schwaiger, Karin
  last_name: Schwaiger
- first_name: Manfred
  full_name: Gareis, Manfred
  last_name: Gareis
- first_name: Christoph
  full_name: Gottschalk, Christoph
  last_name: Gottschalk
citation:
  ama: 'Ulrich S, Biermaier B, Bader O, et al. Identification of Stachybotrys spp.
    by MALDI-TOF mass spectrometry. <i>  Analytical &#38; bioanalytical chemistry :
    a merger of Fresenius’ journal of analytical chemistry, Analusis and Quimica analitica</i>.
    2016;408(27):7565-7581. doi:<a href="https://doi.org/10.1007/s00216-016-9800-9">10.1007/s00216-016-9800-9</a>'
  apa: 'Ulrich, S., Biermaier, B., Bader, O., Wolf, G., Straubinger, R. K., Didier,
    A., Sperner, B., Schwaiger, K., Gareis, M., &#38; Gottschalk, C. (2016). Identification
    of Stachybotrys spp. by MALDI-TOF mass spectrometry. <i>  Analytical &#38; Bioanalytical
    Chemistry : A Merger of Fresenius’ Journal of Analytical Chemistry, Analusis and
    Quimica Analitica</i>, <i>408</i>(27), 7565–7581. <a href="https://doi.org/10.1007/s00216-016-9800-9">https://doi.org/10.1007/s00216-016-9800-9</a>'
  bjps: '<b>Ulrich S <i>et al.</i></b> (2016) Identification of Stachybotrys Spp.
    by MALDI-TOF Mass Spectrometry. <i>  Analytical &#38; bioanalytical chemistry :
    a merger of Fresenius’ journal of analytical chemistry, Analusis and Quimica analitica</i>
    <b>408</b>, 7565–7581.'
  chicago: 'Ulrich, Sebastian, Barbara Biermaier, Oliver Bader, Georg Wolf, Reinhard
    K. Straubinger, Andrea Didier, Brigitte Sperner, Karin Schwaiger, Manfred Gareis,
    and Christoph Gottschalk. “Identification of Stachybotrys Spp. by MALDI-TOF Mass
    Spectrometry.” <i>  Analytical &#38; Bioanalytical Chemistry : A Merger of Fresenius’
    Journal of Analytical Chemistry, Analusis and Quimica Analitica</i> 408, no. 27
    (2016): 7565–81. <a href="https://doi.org/10.1007/s00216-016-9800-9">https://doi.org/10.1007/s00216-016-9800-9</a>.'
  chicago-de: 'Ulrich, Sebastian, Barbara Biermaier, Oliver Bader, Georg Wolf, Reinhard
    K. Straubinger, Andrea Didier, Brigitte Sperner, Karin Schwaiger, Manfred Gareis
    und Christoph Gottschalk. 2016. Identification of Stachybotrys spp. by MALDI-TOF
    mass spectrometry. <i>  Analytical &#38; bioanalytical chemistry : a merger of
    Fresenius’ journal of analytical chemistry, Analusis and Quimica analitica</i>
    408, Nr. 27: 7565–7581. doi:<a href="https://doi.org/10.1007/s00216-016-9800-9">10.1007/s00216-016-9800-9</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;"><span style="font-variant:small-caps;">Ulrich,
    Sebastian</span> ; <span style="font-variant:small-caps;">Biermaier, Barbara</span>
    ; <span style="font-variant:small-caps;">Bader, Oliver</span> ; <span style="font-variant:small-caps;">Wolf,
    Georg</span> ; <span style="font-variant:small-caps;">Straubinger, Reinhard K.</span>
    ; <span style="font-variant:small-caps;">Didier, Andrea</span> ; <span style="font-variant:small-caps;">Sperner,
    Brigitte</span> ; <span style="font-variant:small-caps;">Schwaiger, Karin</span>
    ; u. a.</span>: Identification of Stachybotrys spp. by MALDI-TOF mass spectrometry.
    In: <i>  Analytical &#38; bioanalytical chemistry : a merger of Fresenius’ journal
    of analytical chemistry, Analusis and Quimica analitica</i> Bd. 408. Berlin ;
    Heidelberg, Springer (2016), Nr. 27, S. 7565–7581'
  havard: 'S. Ulrich, B. Biermaier, O. Bader, G. Wolf, R.K. Straubinger, A. Didier,
    B. Sperner, K. Schwaiger, M. Gareis, C. Gottschalk, Identification of Stachybotrys
    spp. by MALDI-TOF mass spectrometry,   Analytical &#38; Bioanalytical Chemistry :
    A Merger of Fresenius’ Journal of Analytical Chemistry, Analusis and Quimica Analitica.
    408 (2016) 7565–7581.'
  ieee: 'S. Ulrich <i>et al.</i>, “Identification of Stachybotrys spp. by MALDI-TOF
    mass spectrometry,” <i>  Analytical &#38; bioanalytical chemistry : a merger of
    Fresenius’ journal of analytical chemistry, Analusis and Quimica analitica</i>,
    vol. 408, no. 27, pp. 7565–7581, 2016, doi: <a href="https://doi.org/10.1007/s00216-016-9800-9">10.1007/s00216-016-9800-9</a>.'
  mla: 'Ulrich, Sebastian, et al. “Identification of Stachybotrys Spp. by MALDI-TOF
    Mass Spectrometry.” <i>  Analytical &#38; Bioanalytical Chemistry : A Merger of
    Fresenius’ Journal of Analytical Chemistry, Analusis and Quimica Analitica</i>,
    vol. 408, no. 27, 2016, pp. 7565–81, <a href="https://doi.org/10.1007/s00216-016-9800-9">https://doi.org/10.1007/s00216-016-9800-9</a>.'
  short: 'S. Ulrich, B. Biermaier, O. Bader, G. Wolf, R.K. Straubinger, A. Didier,
    B. Sperner, K. Schwaiger, M. Gareis, C. Gottschalk,   Analytical &#38; Bioanalytical
    Chemistry : A Merger of Fresenius’ Journal of Analytical Chemistry, Analusis and
    Quimica Analitica 408 (2016) 7565–7581.'
  ufg: '<b>Ulrich, Sebastian u. a.</b>: Identification of Stachybotrys spp. by MALDI-TOF
    mass spectrometry, in: <i>  Analytical &#38; bioanalytical chemistry : a merger
    of Fresenius’ journal of analytical chemistry, Analusis and Quimica analitica</i>
    408 (2016), H. 27,  S. 7565–7581.'
  van: 'Ulrich S, Biermaier B, Bader O, Wolf G, Straubinger RK, Didier A, et al. Identification
    of Stachybotrys spp. by MALDI-TOF mass spectrometry.   Analytical &#38; bioanalytical
    chemistry : a merger of Fresenius’ journal of analytical chemistry, Analusis and
    Quimica analitica. 2016;408(27):7565–81.'
date_created: 2025-06-15T10:32:52Z
date_updated: 2025-06-18T12:11:46Z
department:
- _id: DEP4010
doi: 10.1007/s00216-016-9800-9
extern: '1'
intvolume: '       408'
issue: '27'
keyword:
- Stachybotrys spp
- MALDI-TOF MS
- Mass spectrometry
- Filamentous fungi
language:
- iso: eng
page: 7565-7581
place: Berlin ; Heidelberg
publication: '  Analytical & bioanalytical chemistry : a merger of Fresenius'' journal
  of analytical chemistry, Analusis and Quimica analitica'
publication_identifier:
  eissn:
  - 1618-2650
  issn:
  - 1618-2642
publication_status: published
publisher: Springer
quality_controlled: '1'
status: public
title: Identification of Stachybotrys spp. by MALDI-TOF mass spectrometry
type: scientific_journal_article
user_id: '83781'
volume: 408
year: '2016'
...