---
_id: '12964'
abstract:
- lang: eng
  text: Antibodies represent an important element in the adaptive immune response
    and a major tool to eliminate microbial pathogens. For many bacterial and viral
    infections, efficient vaccines exist, but not for fungal pathogens. For a long
    time, antibodies have been assumed to be of minor importance for a successful
    clearance of fungal infections; however this perception has been challenged by
    a large number of studies over the last three decades. In this review, we focus
    on the potential therapeutic and prophylactic use of monoclonal antibodies. Since
    systemic mycoses normally occur in severely immunocompromised patients, a passive
    immunization using monoclonal antibodies is a promising approach to directly attack
    the fungal pathogen and/or to activate and strengthen the residual antifungal
    immune response in these patients.
article_number: '22'
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Frank
  full_name: Ebel, Frank
  last_name: Ebel
citation:
  ama: Ulrich S, Ebel F. Monoclonal Antibodies as Tools to Combat Fungal Infections.
    <i>Journal of Fungi</i>. 2020;6(1). doi:<a href="https://doi.org/10.3390/jof6010022">10.3390/jof6010022</a>
  apa: Ulrich, S., &#38; Ebel, F. (2020). Monoclonal Antibodies as Tools to Combat
    Fungal Infections. <i>Journal of Fungi</i>, <i>6</i>(1), Article 22. <a href="https://doi.org/10.3390/jof6010022">https://doi.org/10.3390/jof6010022</a>
  bjps: <b>Ulrich S and Ebel F</b> (2020) Monoclonal Antibodies as Tools to Combat
    Fungal Infections. <i>Journal of Fungi</i> <b>6</b>.
  chicago: Ulrich, Sebastian, and Frank Ebel. “Monoclonal Antibodies as Tools to Combat
    Fungal Infections.” <i>Journal of Fungi</i> 6, no. 1 (2020). <a href="https://doi.org/10.3390/jof6010022">https://doi.org/10.3390/jof6010022</a>.
  chicago-de: Ulrich, Sebastian und Frank Ebel. 2020. Monoclonal Antibodies as Tools
    to Combat Fungal Infections. <i>Journal of Fungi</i> 6, Nr. 1. doi:<a href="https://doi.org/10.3390/jof6010022">10.3390/jof6010022</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Ulrich, Sebastian</span> ;
    <span style="font-variant:small-caps;">Ebel, Frank</span>: Monoclonal Antibodies
    as Tools to Combat Fungal Infections. In: <i>Journal of Fungi</i> Bd. 6. Basel,
    MDPI  (2020), Nr. 1'
  havard: S. Ulrich, F. Ebel, Monoclonal Antibodies as Tools to Combat Fungal Infections,
    Journal of Fungi. 6 (2020).
  ieee: 'S. Ulrich and F. Ebel, “Monoclonal Antibodies as Tools to Combat Fungal Infections,”
    <i>Journal of Fungi</i>, vol. 6, no. 1, Art. no. 22, 2020, doi: <a href="https://doi.org/10.3390/jof6010022">10.3390/jof6010022</a>.'
  mla: Ulrich, Sebastian, and Frank Ebel. “Monoclonal Antibodies as Tools to Combat
    Fungal Infections.” <i>Journal of Fungi</i>, vol. 6, no. 1, 22, 2020, <a href="https://doi.org/10.3390/jof6010022">https://doi.org/10.3390/jof6010022</a>.
  short: S. Ulrich, F. Ebel, Journal of Fungi 6 (2020).
  ufg: '<b>Ulrich, Sebastian/Ebel, Frank</b>: Monoclonal Antibodies as Tools to Combat
    Fungal Infections, in: <i>Journal of Fungi</i> 6 (2020), H. 1.'
  van: Ulrich S, Ebel F. Monoclonal Antibodies as Tools to Combat Fungal Infections.
    Journal of Fungi. 2020;6(1).
date_created: 2025-06-15T10:17:00Z
date_updated: 2025-06-18T11:13:40Z
department:
- _id: DEP4010
doi: 10.3390/jof6010022
extern: '1'
intvolume: '         6'
issue: '1'
keyword:
- monoclonal antibodies
- invasive fungal infections
- therapy
- prophylaxis
- opsonization
language:
- iso: eng
place: Basel
publication: Journal of Fungi
publication_identifier:
  eissn:
  - 2309-608X
publication_status: published
publisher: 'MDPI '
quality_controlled: '1'
status: public
title: Monoclonal Antibodies as Tools to Combat Fungal Infections
type: scientific_journal_article
user_id: '83781'
volume: 6
year: '2020'
...