@inproceedings{2954, author = {{Materna, Daniel}}, location = {{Bremen}}, title = {{{Reanalysis for configurational changes}}}, year = {{2015}}, } @misc{2985, author = {{Hernández Rodriguez, Tanja and Pörtner, R. and Frahm, Björn}}, location = {{Hamburg, Germany}}, title = {{{Considerations for cell passaging in cell culture seed trains}}}, year = {{2015}}, } @misc{2986, author = {{Kern, S. and Platas, O. and Schaletzky, M. and Sandig, V. and Frahm, Björn and Pörtner, R.}}, location = {{Hamburg, Germany}}, title = {{{Model-based strategy for cell culture seed train layout verified at lab scale}}}, year = {{2015}}, } @misc{2987, author = {{Hernández Rodriguez, Tanja and Pörtner, R. and Frahm, Björn}}, location = {{Munic, Germany}}, title = {{{A software tool for biopharmaceutical seed train design and optimization}}}, year = {{2015}}, } @misc{2988, author = {{Hernández Rodriguez, Tanja and Pörtner, R. and Frahm, Björn}}, location = {{Barcelona, Spain}}, title = {{{Considerations for cell passaging in cell culture seed trains}}}, year = {{2015}}, } @misc{2990, author = {{Kern, S. and Platas, O. and Schaletzky, M. and Sandig, V. and Frahm, Björn and Pörtner, R.}}, location = {{Barcelona, Spain}}, title = {{{Model-based strategy for cell culture seed train layout verified at lab scale}}}, year = {{2015}}, } @inbook{3034, author = {{Hinken, L. and Austermann-Haun, Ute and Meyer, H. and Urban, I.}}, booktitle = {{Anaerobtechnik}}, editor = {{Rosenwinkel, K.-H. and Kroiss, H. and Dichtl, N. and Seyfried, C.-F. and Weiland, P.}}, publisher = {{Springer}}, title = {{{Anaerobe Abwasserbehandlung}}}, year = {{2015}}, } @inbook{3035, author = {{Hinken, L. and Austermann-Haun, Ute and Meyer, H. and Urban, I.}}, booktitle = {{Anaerobtechnik}}, editor = {{Rosenwinkel, K.-H. and Kroiss, H. and Dichtl, N. and Seyfried, C.-F. and Weiland, P.}}, publisher = {{Springer}}, title = {{{Erfrischungsgetränkeindustrie}}}, year = {{2015}}, } @inbook{3036, author = {{Hinken, L. and Austermann-Haun, Ute and Meyer, H. and Urban, I.}}, booktitle = {{Anaerobtechnik}}, editor = {{Rosenwinkel, K.-H. and Kroiss, H. and Dichtl, N. and Seyfried, C.-F. and Weiland, P.}}, publisher = {{Springer}}, title = {{{Pektinfabriken}}}, year = {{2015}}, } @article{3094, author = {{Fettig, Joachim and Austermann-Haun, Ute and Liebe, H. and Meier, J. F. and Wichern, M.}}, journal = {{KA Korrespondenz Abwasser Abfall}}, number = {{6}}, pages = {{529 -- 536}}, title = {{{Ein Konzept zur Behandlung von Prozesswässern aus der Hydrothermalen Carbonisierung }}}, volume = {{62}}, year = {{2015}}, } @inproceedings{3136, author = {{Austermann-Haun, Ute}}, location = {{Mumbai, Indien}}, title = {{{Elimination of micro-pollutants in municipal wastewater treatment plants}}}, year = {{2015}}, } @inproceedings{3190, author = {{Austermann-Haun, Ute}}, location = {{Rheda-Wiedenbrück}}, title = {{{Kläranlage: So passt man die Technik an! Möglichkeiten der Anpassung an den Wandel}}}, year = {{2015}}, } @inproceedings{3191, author = {{Austermann-Haun, Ute}}, location = {{Gießen}}, title = {{{Industrieabwasser als Energiequelle - das Forschungsvorhaben AMBER als Baustein einer energieeffizienten Abwasserentsorgung}}}, year = {{2015}}, } @inproceedings{4460, author = {{Kutz, Gerd and Schubert, O. E.}}, location = {{Hochschule Ostwestfalen-Lippe Detmold}}, title = {{{APV basics}}}, year = {{2015}}, } @inproceedings{4461, author = {{Kutz, Gerd and Schubert, O. E.}}, location = {{Darmstadt}}, title = {{{APV basics}}}, year = {{2015}}, } @inproceedings{4605, author = {{Pethig, Florian and Schriegel, Sebastian and Jasperneite, Jürgen and Witte, Stefan}}, booktitle = {{Die Energiewende : blueprints for the new energy age ; International ETG Congress 2015, November 17-18, 2015, World Conference Center, Bonn }}, editor = {{Speh, Rainer}}, isbn = {{978-3-8007-4121-2}}, location = {{Bonn}}, pages = {{527--533}}, publisher = {{VDI-Verl.}}, title = {{{EMiLippe - Business E-Mobility in the Rural Region of Ostwestfalen-Lippe based on Renewable Energy}}}, volume = {{147}}, year = {{2015}}, } @inproceedings{4606, author = {{Dürkop, Lars and Wisniewski, Lukasz and Heymann, Sascha and Lücke, Benedikt and Priss, Philip and Jasperneite, Jürgen}}, booktitle = {{KommA 2015 – Jahreskolloquium Kommunikation in der Automation}}, title = {{{Analyse des Inbetriebnahmeaufwandes von industriellen Produktionsanlagen anhand von Anwendungsbeispielen}}}, year = {{2015}}, } @inproceedings{4607, abstract = {{Usage of Retrofitting for Migration of Industrial Production Lines to Industry 4.0 Abstract: Today the term Industry 4.0 (I4.0) is omnipresent and many machine builders want to benefit from the researched advantages by integrating this new technologies such as OPC UA into their products. However, due to financial reasons it is not feasible to exchange existing industrial production lines with the new I4.0 ready technologies at once. Therefore this paper will propose a retrofitting approach for the gradual migration to I4.0 by providing a defined schedule with milestones and showing different problems which can occur during retrofitting. In addition to that a new business model called Retrofitting as a Service (RaaS) for future companies will be introduced to show a possible usage of retrofitting. }}, author = {{Ehrlich, Marco and Wisniewski, Lukasz and Jasperneite, Jürgen}}, booktitle = {{KommA 2015 – Jahreskolloquium Kommunikation in der Automation}}, title = {{{Usage of Retrofitting for Migration of Industrial Production Lines to Industry 4.0}}}, year = {{2015}}, } @article{4608, author = {{Schleipen, Miriam and Lüder, Arndt and Sauer, Olaf and Flatt, Holger and Jasperneite, Jürgen}}, journal = {{at - Automatisierungstechnik}}, pages = {{801–820}}, title = {{{Anforderungen und Konzepte für Plug-and-Work - Adaptivität im Kontext von Industrie 4.0}}}, volume = {{63}}, year = {{2015}}, } @article{4609, author = {{Beyerer, Jürgen and Jasperneite, Jürgen and Sauer, Olaf}}, journal = {{at - Automatisierungstechnik}}, pages = {{751–752}}, title = {{{Industrie 4.0}}}, volume = {{63}}, year = {{2015}}, } @inproceedings{4610, author = {{Schriegel, Sebastian and Biendarra, Alexander and Ronen, Opher and Flatt, Holger and Lessmann, Gunnar and Jasperneite, Jürgen}}, booktitle = {{ISPCS 2015}}, title = {{{Automatic Determination of Synchronization Path Quality using PTP Bridges with Integrated Inaccuracy Estimation for System Configuration and Monitoring}}}, year = {{2015}}, } @article{4611, author = {{Jasperneite, Jürgen and Lohweg, Volker}}, journal = {{ETZ (2015)}}, pages = {{32 -- 35d}}, title = {{{Intelligente Vernetzung für die fexible Produktion von morgen}}}, volume = {{10}}, year = {{2015}}, } @inproceedings{4612, author = {{Jasperneite, Jürgen}}, booktitle = {{Workshop Industrie 4.0: Informatik gestaltet neue Produktionssysteme anlässlich 45. Jahrestagung der Gesellschaft für Informatik (invited talk)}}, publisher = {{GI}}, title = {{{Smart Factory based on intelligent technical systems }}}, year = {{2015}}, } @inproceedings{4613, author = {{Ax, Johannes and Buda, Aurel and Schneider, Daniel and Hartfiel, John and Dürkop, Lars and Jungeblut, Thorsten and Jasperneite, Jürgen and Vedral, Andreas and Rückert, Ulrich}}, booktitle = {{GI-Edition - Lecture Notes in Informatics (LNI): INFORMATIK 2015}}, title = {{{Universelle Echtzeit-Ethernet Architektur zur Integration in rekonfigurierbare Automatisierungssysteme}}}, year = {{2015}}, } @inproceedings{4614, author = {{Jasperneite, Jürgen}}, booktitle = {{25 Jahre DFAM-Symposium "Stand und zukünftige Entwicklungen von Mikroelektronik und Automatisierung" (eingeladener Vortrag) }}, publisher = {{Deutsche Forschungsgesellschaft für Automatisierung und Mikroelektronik e.V. (DFAM)}}, title = {{{Zukünftige Entwicklungen der industriellen Kommunikation }}}, year = {{2015}}, } @inproceedings{4615, author = {{Dürkop, Lars and Wisniewski, Lukasz and Heymann, Sascha and Lücke, Benedikt and Jasperneite, Jürgen}}, booktitle = {{20th IEEE International Conference on Emerging Technologies and Factory Automation (ETFA)}}, title = {{{Analyzing the engineering effort for the commissioning of industrial automation systems}}}, year = {{2015}}, } @inproceedings{4616, author = {{Henneke, Dominik and Elattar, Mohammad and Jasperneite, Jürgen}}, booktitle = {{IEEE International Conference on Emerging Technologies and Factory Automation (ETFA 2015)}}, title = {{{Communication Patterns for Cyber-Physical Systems}}}, year = {{2015}}, } @inproceedings{4617, author = {{Flatt, Holger and Koch, Nils and Guenter, Andrei and Röcker, Carsten and Jasperneite, Jürgen}}, booktitle = {{ETFA 2015}}, title = {{{A Context-Aware Assistance System for Maintenance Applications in Smart Factories based on Augmented Reality and Indoor Localization}}}, year = {{2015}}, } @inproceedings{4618, author = {{Neumann, Arne and Wisniewski, Lukasz and Jasperneite, Jürgen}}, booktitle = {{9th International Workshop on Service-Oriented Cyber-Physical Systems in Converging Networked Environments (SOCNE)}}, title = {{{Utilizing OPC UA as comprehensive communication technology for Cyber Physical Production Systems}}}, year = {{2015}}, } @inproceedings{4619, author = {{Wisniewski, Lukasz and Schumacher, Markus and Jasperneite, Jürgen and Diedrich, Christian}}, booktitle = {{20th IEEE International Conference on Emerging Technologies and Factory Automation}}, publisher = {{IEEE}}, title = {{{Increasing Flexibility of Time Triggered Ethernet based Systems by Optimal Greedy Scheduling Approach}}}, year = {{2015}}, } @inproceedings{4620, author = {{Windmann, Stefan and Jasperneite, Jürgen}}, booktitle = {{IEEE International Conference on Emerging Technologies and Factory Automation (ETFA 2015)}}, title = {{{An FPGA Based FIFO with Efficient Memory Management}}}, year = {{2015}}, } @inproceedings{4621, author = {{Wisniewski, Lukasz and Jasperneite, Jürgen and Diedrich, Christian}}, title = {{{Increasing Flexibility of Cyber Physical Systems (CPS) by Optimal Greedy Scheduling of Communication in Time Triggered Ethernet based Networks}}}, year = {{2015}}, } @inproceedings{4622, author = {{Elattar, Mohammad and Dürkop, Lars and Jasperneite, Jürgen}}, booktitle = {{13th IEEE International Conference on Industrial Informatics (INDIN 2015)}}, title = {{{Utilizing LTE QoS Features to Provide Reliable Access Network for Cyber-Physical Systems}}}, year = {{2015}}, } @inproceedings{4623, author = {{Heymann, Sascha and Jasperneite, Jürgen and Schröck, Sebastian and Fay, Alexander}}, booktitle = {{Automation 2015}}, title = {{{Beschreibung von Produktionsprozessen in modularisierten Produktionsanlagen für Industrie 4.0}}}, year = {{2015}}, } @inproceedings{4624, author = {{Jasperneite, Jürgen}}, booktitle = {{22. ERP-Tage (Vortrag)}}, title = {{{Wie die Intelligenz in die Maschine kommt!}}}, year = {{2015}}, } @article{4625, author = {{Jasperneite, Jürgen and Neumann, Arne and Pethig, Florian}}, journal = {{ComputerAutomation }}, pages = {{16--21}}, title = {{{OPC UA versus MTConnect}}}, volume = {{Sonderheft S2 2015 ControlDrives}}, year = {{2015}}, } @inproceedings{4626, author = {{Dürkop, Lars and Jasperneite, Jürgen and Fay, Alexander}}, booktitle = {{11th IEEE World Conference on Factory Communication Systems (WFCS 2015)}}, publisher = {{Palma de Mallorca, Spain}}, title = {{{An Analysis of Real-Time Ethernets With Regard to Their Automatic Configuration}}}, year = {{2015}}, } @inproceedings{4627, author = {{Wisniewski, Lukasz and Chahar, Satendrasingh Y and Jasperneite, Jürgen}}, booktitle = {{11th IEEE World Conference on Factory Communication Systems (WFCS 2015)}}, publisher = {{IEEE}}, title = {{{Seamless reconfiguration of Time Triggered Ethernet protocols}}}, year = {{2015}}, } @inproceedings{4628, author = {{Elattar, Mohammad and Jasperneite, Jürgen}}, booktitle = {{11th IEEE World Conference on Factory Communication Systems (WFCS 2015)}}, title = {{{Using LTE as an Access Network for Internet-Based Cyber-Physical Systems}}}, year = {{2015}}, } @inproceedings{4629, author = {{Jasperneite, Jürgen}}, booktitle = {{Produktivitätsfortschritte durch Industrie 4.0}}, pages = {{8--9}}, publisher = {{VDMA-Verlag GmbH}}, title = {{{Wenn Assistenzsysteme den Menschen unterstützen und entlasten}}}, year = {{2015}}, } @inproceedings{4630, author = {{Jasperneite, Jürgen}}, booktitle = {{Industrie 4.0 und sichere Kommunikation - Akteure berichten von ihren Projekten (eingeladener Vortrag)}}, publisher = {{VDI/VDE GMA Berlin-Brandenburg}}, title = {{{Smart Factory - aktueller Status}}}, year = {{2015}}, } @inproceedings{4631, author = {{Jasperneite, Jürgen}}, booktitle = {{20. Industrial Communication Congress (Vortrag)}}, title = {{{Industrie 4.0 und intelligente Vernetzung - Technologietransfer am Beispiel eines it´s OWL Projektes}}}, year = {{2015}}, } @inproceedings{4633, author = {{Dürkop, Lars and Czybik, Björn and Jasperneite, Jürgen}}, booktitle = {{18th International Conference on Intelligence in Next Generation Networks (ICIN), Paris}}, title = {{{Performance Evaluation of M2M Protocols Over Cellular Networks in a Lab Environment}}}, year = {{2015}}, } @inproceedings{4634, author = {{Jasperneite, Jürgen}}, booktitle = {{Ligna Preview 2015}}, title = {{{How Machines will become intelligent?}}}, year = {{2015}}, } @inproceedings{4793, author = {{Diedrich, Alexander and Bunte, Andreas and Maier, Alexander and Niggemann, Oliver}}, booktitle = {{Machine Learning for Cyber Physical Systems and Industry 4.0 (ML4CPS)}}, title = {{{Kognitive Architektur zum Konzeptlernen in technischen Systemen}}}, year = {{2015}}, } @inproceedings{4794, author = {{Niggemann, Oliver and Biswas, Gautam and Kinnebrew, John S. and Khorasgani, Hamed and Volgmann, Sören and Bunte, Andreas}}, booktitle = {{International Workshop on the Principles of Diagnosis (DX)}}, title = {{{Data-Driven Monitoring of Cyber-Physical Systems Leveraging on Big Data and the Internet-of-Things for Diagnosis and Control}}}, year = {{2015}}, } @inproceedings{4802, author = {{Böttcher, Björn and Moriz, Natalia and Niggemann, Oliver}}, booktitle = {{Automation 2015}}, publisher = {{VDI-Verlag}}, title = {{{Intelligente Entwurfsassistenz für Automatisierungssysteme - Vorteile deklarativer Paradigmen im Systementwurf}}}, year = {{2015}}, } @book{4901, author = {{Borcherding, Arnold and Heidemann, Klaus and Nerreter, Wolfgang}}, isbn = {{978-3-446-44268-9}}, issn = {{978-3-446-44337-2 }}, pages = {{159}}, publisher = {{Carl Hanser Verlag}}, title = {{{Aufgaben : 120 Aufgaben mit Lösungen }}}, volume = {{3}}, year = {{2015}}, } @misc{10167, abstract = {{This paper discusses an alternative to common Powerline or Power-over-Ethernet applications, combining a 100BASE-TX-equivalent full duplex communication and simultaneous DC power transmission on one single twisted pair wire. The reduction of wires and connections can potentially ease the modularity and reconfigurability of industrial production installations, if the data communication offers a sufficiently high robustness against influences from the DC power transmission. This part of our research focuses on the necessary electrical adaptations between data and power circuitry and evaluates interference scenarios that are common for industrial fieldbus installations.}}, author = {{Wesemann, Derk and Dünnermann, Jens and Schaller, Marian and Banick, Norman and Witte, Stefan}}, booktitle = {{2015 IEEE World Conference on Factory Communication Systems (WFCS)}}, keywords = {{Wires, Transmission line measurements, Transceivers, Data communication, Power transmission lines, Wiring, Inductance}}, location = {{Palma de Mallorca, Spain}}, publisher = {{IEEE}}, title = {{{Less wires — A novel approach on combined power and ethernet transmission on a single, unshielded twisted pair cable}}}, doi = {{10.1109/WFCS.2015.7160588}}, year = {{2015}}, } @inproceedings{10224, abstract = {{Optical interconnects on printed circuit board level are a promising choice to support high bandwidth for short distance interconnects. These interconnects consists of highly multimode step index waveguides with rectangular core cross sections. Therefore ray tracing is an excellent method to determine the optical path parameters, e.g. optical power, ray path lengths and local ray directions. Based on these parameters the step response, the transient transfer function and the coupling behavior can be calculated. Classical ray tracing methods calculates the optical path parameters of each ray by successively computing internal reflections until a termination condition is reached. Therefore the computing time depends on the number of internal reflections. If the optical waveguide consists of cascaded straight and curved segments, e. g. point-to-point interconnects, one can use the analytic ray tracing method to determine the optical path parameters. The whole path parameters of each ray are determined by one analytical computation. The computing time depends on the number of segments. The analytic ray tracing method is unusable to determine ray path parameters of segments with varying core cross sections, e.g. tapers, crossings, splitters and combiners.}}, author = {{Stübbe, Oliver}}, booktitle = {{Optical Interconnects XVII}}, editor = {{Schröder, Henning and Chen, Ray T.}}, issn = {{0277-786X}}, location = {{San Francisco}}, publisher = {{SPIE}}, title = {{{Semi-analytic ray tracing method for time-efficient computing of transmission behavior of PCB level optical interconnects with varying core cross sections}}}, doi = {{10.1117/12.2076931}}, volume = {{9368}}, year = {{2015}}, } @article{1025, abstract = {{Coagulation is an essential process for the removal of suspended and colloidal material from water and wastewater. However, no comprehensive or universally accepted mathematical description of the process has been developed so far. Therefore, process optimization and control is usually based on data from jar tests and simple flow-proportional dosing concepts, while more accurate concepts based on water quality parameters that can be measured online are emerging. In addition, there have been attempts to develop software sensors and control schemes that involve advanced mathematical analyses of these parameters. The paper presents an overview of the parameters and physical sensors that are used for feed-forward and feed-backward control schemes and the experiences that have been made with their implementation. Moreover, the development and use of software sensors is described. Finally, the practical applications of different control techniques are given in order to illustrate the state of the art of coagulation control. Some thoughts about research needs conclude this review.}}, author = {{Ratnaweera, Harsha and Fettig, Joachim}}, issn = {{2073-4441}}, journal = {{Water}}, number = {{11}}, pages = {{6574--6597}}, title = {{{State of the Art of Online Monitoring and Control of the Coagulation Process}}}, doi = {{10.3390/w7116574}}, volume = {{7}}, year = {{2015}}, } @misc{12244, abstract = {{In this paper the concept of resilience is discussed on the base of 13 case studies from the German branch of the International Long-Term Ecological Research Program. In the introduction the resilience approach is presented as one possibility to describe ecosystem dynamics. The relations with the concepts of adaptability and ecological integrity are discussed and the research questions are formulated. The focal research objectives are related to the conditions of resilient behaviour of ecosystems, the role of spatio-temporal scales, the differences between short- or long-term dynamics, the basic methodological requirements to exactly define resilience, the role of the reference state and indicators and the suitability of resilience as a management concept. The main part of the paper consists of 13 small case study descriptions, which demonstrate phase transitions and resilient dynamics of several terrestrial and aquatic ecosystems at different time scales. In the discussion, some problems arising from the interpretation of the time series are highlighted and discussed. The topics of discussion are the conceptual challenges of the resilience approach, methodological problems, the role of indicator selection, the complex interactions between different disturbances, the significance of time scales and a comparison of the case studies. The article ends with a conclusion which focuses on the demand to link resilience with adaptability, in order to support the long-term dynamics of ecosystem development.}}, author = {{Müller, F. and Bergmann, M. and Dannowski, R. and Dippner, J.W. and Gnauck, A. and Haase, P. and Jochimsen, Marc C. and Kasprzak, P. and Kröncke, I. and Kümmerlin, R. and Küster, M. and Lischeid, G. and Meesenburg, H. and Merz, C. and Millat, G. and Müller, J. and Padisák, J. and Schimming, C.G. and Schubert, H. and Schult, M. and Selmeczy, G. and Shatwell, Tom and Stoll, S. and Schwabe, M. and Soltwedel, T. and Straile, D. and Theuerkauf, M.}}, booktitle = {{ Ecological indicators : integrating monitoring, assessment and management}}, issn = {{1872-7034}}, keywords = {{Long-term ecological research, LTER, Ecosystem resilience and adaptability, Spatio-temporal scales, Indicator selection}}, number = {{6}}, pages = {{10--43}}, publisher = {{Elsevier BV}}, title = {{{Assessing resilience in long-term ecological data sets}}}, doi = {{10.1016/j.ecolind.2015.10.066}}, volume = {{65}}, year = {{2015}}, } @misc{12245, abstract = {{Rewetting of long-term drained fens often results in the formation of eutrophic shallow lakes with an average water depth of less than 1 m. This is accompanied by a fast vegetation shift from cultivated grasses via submerged hydrophytes to helophytes. As a result of rapid plant dying and decomposition, these systems are highly dynamic wetlands characterised by a high mobilisation of nutrients and elevated emissions of CO2 and CH4. However, the impact of specific plant species on these phenomena is not clear. Therefore we investigated the CO2 and CH4 production due to the subaqueous decomposition of shoot biomass of five selected plant species which represent different rewetting stages (Phalaris arundinacea, Ceratophyllum demersum, Typha latifolia, Phragmites australis and Carex riparia) during a 154 day mesocosm study. Beside continuous gas flux measurements, we performed bulk chemical analysis of plant tissue, including carbon, nitrogen, phosphorus and plant polymer dynamics. Plant-specific mass losses after 154 days ranged from 25% (P. australis) to 64% (C. demersum). Substantial differences were found for the CH4 production with highest values from decomposing C. demersum (0.4 g CH4 kg−1 dry mass day) that were about 70 times higher than CH4 production from C. riparia. Thus, we found a strong divergence between mass loss of the litter and methane production during decomposition. If C. demersum as a hydrophyte is included in the statistical analysis solely nutrient contents (nitrogen and phosphorus) explain varying greenhouse gas production of the different plant species while lignin and polyphenols demonstrate no significant impact at all. Taking data of annual biomass production as important carbon source for methanogens into account, high CH4 emissions can be expected to last several decades as long as inundated and nutrient-rich conditions prevail. Different restoration measures like water level control, biomass extraction and top soil removal are discussed in the context of mitigation of CH4 emissions from rewetted fens.}}, author = {{Zak, D. and Reuter, H. and Augustin, J. and Shatwell, Tom and Barth, M. and Gelbrecht, J. and McInnes, R. J.}}, booktitle = {{Biogeosciences}}, issn = {{1726-4189}}, number = {{8}}, pages = {{2455--2468}}, publisher = {{Copernicus GmbH}}, title = {{{Changes of the CO2 and CH4 production potential of rewetted fens in the perspective of temporal vegetation shifts }}}, doi = {{10.5194/bg-12-2455-2015}}, volume = {{12}}, year = {{2015}}, } @misc{12978, abstract = {{Diet change and fatness are supposed to challenge the immune system of the cow. Therefore, immunological and haematological consequences of adaptation to and continued feeding of a high-energy diet were studied in eight non-pregnant, non-lactating Holstein cows over 16 weeks. Blood haptoglobin concentration remained unaltered, suggesting that an acute phase reaction was not induced. Stimulation ability of peripheral blood mononuclear cells and stimulated oxidative burst capacity of granulocytes increased significantly in the course of the experiment after an initial drop. While total leucocyte counts increased, the proportion of granulocytes increased and that of lymphocytes decreased at the same time as the ratio of CD4+/CD8+ lymphocytes did. Capability of rumen microbes to detoxify the immune-modulating mycotoxin deoxynivalenol (DON) was not compromised as indicated by the exclusive presence of de-DON as the detoxified DON metabolite in blood. In conclusion, both diet change and prolonged positive energy balance influenced the bovine immune system.}}, author = {{Dänicke, Sven and Meyer, Ulrich and Winkler, Janine and Ulrich, Sebastian and Frahm, Jana and Kersten, Susanne and Valenta, Hana and Rehage, Jürgen and Häussler, Susanne and Sauerwein, Helga and Locher, Lena}}, booktitle = {{Archives of Animal Nutrition}}, issn = {{1477-2817}}, keywords = {{Dairy cowsdeoxynivalenol, energy consumption, functional responses, haematology, leucocytes, mycotoxins, zearalenone}}, number = {{1}}, pages = {{1--16}}, publisher = {{Taylor & Francis}}, title = {{{Haematological and immunological adaptations of non-pregnant, non-lactating dairy cows to a high-energetic diet containing mycotoxins}}}, doi = {{10.1080/1745039x.2015.1117561}}, volume = {{70}}, year = {{2015}}, }