---
_id: '12792'
abstract:
- lang: eng
  text: Additive Manufacturing has arisen as a ground-breaking set of technologies
    that, thanks to their capability of continuous improvements in performance and
    cost-efficiency, was able in the last years to replace well-established manufacturing
    processes. Proficiency in the fabrication of highly complex parts forced this
    astonishing development. This research is based on the idea that through the integration
    of additive and conventional manufacturing technologies it is possible to achieve
    great cost and operational benefits especially in the field of tool making for
    injection molding. Such an integrated manufacturing solution could overcome the
    limitations of independent additive, subtractive, and post-processing procedures
    by strengthening their potentialities. The present study highlights the opportunities
    of a synergy between the above-mentioned manufacturing technologies for the optimized
    fabrication of injection molds. An additive manufacturing process chain is presented,
    and special attention is given to the surface quality and its optimization directly
    in the Selective Laser Melting process. The potentialities of the Laser Surface
    Re-melting technique are analyzed, and the process optimization leads to a reduction
    of 45% of the average roughness directly in the SLM process. (C) 2019, IFAC (International
    Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.
author:
- first_name: Filippo
  full_name: Simoni, Filippo
  last_name: Simoni
- first_name: Andrea
  full_name: Huxol, Andrea
  id: '43559'
  last_name: Huxol
- first_name: Franz-Josef
  full_name: Villmer, Franz-Josef
  id: '14290'
  last_name: Villmer
citation:
  ama: Simoni F, Huxol A, Villmer FJ. <i>Approach Towards Surface Improvement in Additively
    Manufactured Tools</i>. Vol 52. Elsevier BV; 2019:254-259. doi:<a href="https://doi.org/10.1016/j.ifacol.2019.10.032">10.1016/j.ifacol.2019.10.032</a>
  apa: Simoni, F., Huxol, A., &#38; Villmer, F.-J. (2019). Approach Towards Surface
    Improvement in Additively Manufactured Tools. In <i>13th International-Federation-of-Automatic-Control
    (IFAC) Workshop on Intelligent Manufacturing Systems (IMS)</i> (Vol. 52, pp. 254–259).
    Elsevier BV. <a href="https://doi.org/10.1016/j.ifacol.2019.10.032">https://doi.org/10.1016/j.ifacol.2019.10.032</a>
  bjps: '<b>Simoni F, Huxol A and Villmer F-J</b> (2019) <i>Approach Towards Surface
    Improvement in Additively Manufactured Tools</i>. Amsterdam [u.a.]: Elsevier BV.'
  chicago: 'Simoni, Filippo, Andrea Huxol, and Franz-Josef Villmer. <i>Approach Towards
    Surface Improvement in Additively Manufactured Tools</i>. <i>13th International-Federation-of-Automatic-Control
    (IFAC) Workshop on Intelligent Manufacturing Systems (IMS)</i>. Vol. 52. IFAC-PapersOnLine.
    Amsterdam [u.a.]: Elsevier BV, 2019. <a href="https://doi.org/10.1016/j.ifacol.2019.10.032">https://doi.org/10.1016/j.ifacol.2019.10.032</a>.'
  chicago-de: 'Simoni, Filippo, Andrea Huxol und Franz-Josef Villmer. 2019. <i>Approach
    Towards Surface Improvement in Additively Manufactured Tools</i>. <i>13th International-Federation-of-Automatic-Control
    (IFAC) Workshop on Intelligent Manufacturing Systems (IMS)</i>. Bd. 52. IFAC-PapersOnLine.
    Amsterdam [u.a.]: Elsevier BV. doi:<a href="https://doi.org/10.1016/j.ifacol.2019.10.032">10.1016/j.ifacol.2019.10.032</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Simoni, Filippo</span> ; <span
    style="font-variant:small-caps;">Huxol, Andrea</span> ; <span style="font-variant:small-caps;">Villmer,
    Franz-Josef</span>: <i>Approach Towards Surface Improvement in Additively Manufactured
    Tools</i>, <i>IFAC-PapersOnLine</i>. Bd. 52. Amsterdam [u.a.] : Elsevier BV, 2019'
  havard: F. Simoni, A. Huxol, F.-J. Villmer, Approach Towards Surface Improvement
    in Additively Manufactured Tools, Elsevier BV, Amsterdam [u.a.], 2019.
  ieee: 'F. Simoni, A. Huxol, and F.-J. Villmer, <i>Approach Towards Surface Improvement
    in Additively Manufactured Tools</i>, vol. 52. Amsterdam [u.a.]: Elsevier BV,
    2019, pp. 254–259. doi: <a href="https://doi.org/10.1016/j.ifacol.2019.10.032">10.1016/j.ifacol.2019.10.032</a>.'
  mla: Simoni, Filippo, et al. “Approach Towards Surface Improvement in Additively
    Manufactured Tools.” <i>13th International-Federation-of-Automatic-Control (IFAC)
    Workshop on Intelligent Manufacturing Systems (IMS)</i>, vol. 52, Elsevier BV,
    2019, pp. 254–59, <a href="https://doi.org/10.1016/j.ifacol.2019.10.032">https://doi.org/10.1016/j.ifacol.2019.10.032</a>.
  short: F. Simoni, A. Huxol, F.-J. Villmer, Approach Towards Surface Improvement
    in Additively Manufactured Tools, Elsevier BV, Amsterdam [u.a.], 2019.
  ufg: '<b>Simoni, Filippo/Huxol, Andrea/Villmer, Franz-Josef</b>: Approach Towards
    Surface Improvement in Additively Manufactured Tools, Bd. 52, Amsterdam [u.a.]
    2019 (IFAC-PapersOnLine).'
  van: 'Simoni F, Huxol A, Villmer FJ. Approach Towards Surface Improvement in Additively
    Manufactured Tools. 13th International-Federation-of-Automatic-Control (IFAC)
    Workshop on Intelligent Manufacturing Systems (IMS). Amsterdam [u.a.]: Elsevier
    BV; 2019. (IFAC-PapersOnLine; vol. 52).'
conference:
  end_date: 2019-08-14
  location: Oshawa, CANADA
  name: 13th International-Federation-of-Automatic-Control (IFAC) Workshop on Intelligent
    Manufacturing Systems (IMS)
  start_date: 2019-08-12
date_created: 2025-04-15T09:32:02Z
date_updated: 2025-06-26T13:40:36Z
department:
- _id: DEP7000
doi: 10.1016/j.ifacol.2019.10.032
intvolume: '        52'
keyword:
- Direct rapid tooling
- toolmaking
- additive manufacturing process chain
- process control
- production systems
- selective laser melting
- surface roughness
- laser surface re-melting
language:
- iso: eng
page: 254-259
place: Amsterdam [u.a.]
publication: 13th International-Federation-of-Automatic-Control (IFAC) Workshop on
  Intelligent Manufacturing Systems (IMS)
publication_identifier:
  issn:
  - 2405-8963
publication_status: published
publisher: Elsevier BV
series_title: IFAC-PapersOnLine
status: public
title: Approach Towards Surface Improvement in Additively Manufactured Tools
type: conference_editor_article
user_id: '83781'
volume: 52
year: '2019'
...
---
_id: '12803'
abstract:
- lang: eng
  text: The increasing amount of alarms and information for an operator in a modern
    plant becomes a significant safety risk. Although the notifications are a valuable
    support, they also lead to the curse of overloading with information for the operator.
    Due to the huge amount of alarms it is almost impossible to separate the crucial
    information from the insignificant ones. Therefore, new procedures are required
    to reduce these alarm floods and support the operator to minimize the safety risk.
    One approach is based on learning a causal model that represents the relationships
    between the alarms. This allows alarm sequences that are causally implied to be
    reduced to the root cause alarm. Fundamental element of this approach is the causal
    model. Therefore in this work, different probabilistic graphical models are considered
    and evaluated on the basis of appropriate criteria. A real use case of a bottle
    filling module serves as a benchmark for how well they are suitable as a causal
    model for the application in alarm flood reduction.
author:
- first_name: Paul
  full_name: Wunderlich, Paul
  id: '52317'
  last_name: Wunderlich
- first_name: Nemanja
  full_name: Hranisavljevic, Nemanja
  id: '62376'
  last_name: Hranisavljevic
citation:
  ama: Wunderlich P, Hranisavljevic N. <i>Comparison of Different Probabilistic Graphical
    Models as Causal Models in Alarm Flood Reduction</i>. (Aalto University, Finland,
    Tampere University, Finland, Finnish Society of Automation, Finland, eds.). IEEE;
    2019:1285-1290. doi:<a href="https://doi.org/10.1109/indin41052.2019.8972251">10.1109/indin41052.2019.8972251</a>
  apa: Wunderlich, P., &#38; Hranisavljevic, N. (2019). Comparison of Different Probabilistic
    Graphical Models as Causal Models in Alarm Flood Reduction. In Aalto University,
    Finland, Tampere University, Finland, &#38; Finnish Society of Automation, Finland
    (Eds.), <i>2019 IEEE 17th International Conference on Industrial Informatics (INDIN)</i>
    (pp. 1285–1290). IEEE. <a href="https://doi.org/10.1109/indin41052.2019.8972251">https://doi.org/10.1109/indin41052.2019.8972251</a>
  bjps: '<b>Wunderlich P and Hranisavljevic N</b> (2019) <i>Comparison of Different
    Probabilistic Graphical Models as Causal Models in Alarm Flood Reduction</i>,
    Aalto University, Finland, Tampere University, Finland, and Finnish Society of
    Automation, Finland (eds). [Piscataway, NJ]: IEEE.'
  chicago: 'Wunderlich, Paul, and Nemanja Hranisavljevic. <i>Comparison of Different
    Probabilistic Graphical Models as Causal Models in Alarm Flood Reduction</i>.
    Edited by Aalto University, Finland, Tampere University, Finland, and Finnish
    Society of Automation, Finland. <i>2019 IEEE 17th International Conference on
    Industrial Informatics (INDIN)</i>. [Piscataway, NJ]: IEEE, 2019. <a href="https://doi.org/10.1109/indin41052.2019.8972251">https://doi.org/10.1109/indin41052.2019.8972251</a>.'
  chicago-de: 'Wunderlich, Paul und Nemanja Hranisavljevic. 2019. <i>Comparison of
    Different Probabilistic Graphical Models as Causal Models in Alarm Flood Reduction</i>.
    Hg. von Aalto University, Finland, Tampere University, Finland, und Finnish Society
    of Automation, Finland. <i>2019 IEEE 17th International Conference on Industrial
    Informatics (INDIN)</i>. [Piscataway, NJ]: IEEE. doi:<a href="https://doi.org/10.1109/indin41052.2019.8972251">10.1109/indin41052.2019.8972251</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Wunderlich, Paul</span> ; <span
    style="font-variant:small-caps;">Hranisavljevic, Nemanja</span> ; <span style="font-variant:small-caps;">Aalto
    University, Finland</span> ; <span style="font-variant:small-caps;">Tampere University,
    Finland</span> ; <span style="font-variant:small-caps;">Finnish Society of Automation,
    Finland</span> (Hrsg.): <i>Comparison of Different Probabilistic Graphical Models
    as Causal Models in Alarm Flood Reduction</i>. [Piscataway, NJ] : IEEE, 2019'
  havard: P. Wunderlich, N. Hranisavljevic, Comparison of Different Probabilistic
    Graphical Models as Causal Models in Alarm Flood Reduction, IEEE, [Piscataway,
    NJ], 2019.
  ieee: 'P. Wunderlich and N. Hranisavljevic, <i>Comparison of Different Probabilistic
    Graphical Models as Causal Models in Alarm Flood Reduction</i>. [Piscataway, NJ]:
    IEEE, 2019, pp. 1285–1290. doi: <a href="https://doi.org/10.1109/indin41052.2019.8972251">10.1109/indin41052.2019.8972251</a>.'
  mla: Wunderlich, Paul, and Nemanja Hranisavljevic. “Comparison of Different Probabilistic
    Graphical Models as Causal Models in Alarm Flood Reduction.” <i>2019 IEEE 17th
    International Conference on Industrial Informatics (INDIN)</i>, edited by Aalto
    University, Finland et al., IEEE, 2019, pp. 1285–90, <a href="https://doi.org/10.1109/indin41052.2019.8972251">https://doi.org/10.1109/indin41052.2019.8972251</a>.
  short: P. Wunderlich, N. Hranisavljevic, Comparison of Different Probabilistic Graphical
    Models as Causal Models in Alarm Flood Reduction, IEEE, [Piscataway, NJ], 2019.
  ufg: '<b>Wunderlich, Paul/Hranisavljevic, Nemanja</b>: Comparison of Different Probabilistic
    Graphical Models as Causal Models in Alarm Flood Reduction, hg. von Aalto University,
    Finland/Tampere University, Finland, Finnish Society of Automation, Finland, [Piscataway,
    NJ] 2019.'
  van: 'Wunderlich P, Hranisavljevic N. Comparison of Different Probabilistic Graphical
    Models as Causal Models in Alarm Flood Reduction. Aalto University, Finland, Tampere
    University, Finland, Finnish Society of Automation, Finland, editors. 2019 IEEE
    17th International Conference on Industrial Informatics (INDIN). [Piscataway,
    NJ]: IEEE; 2019.'
conference:
  end_date: 2019-07-25
  location: 'Helsinki, Finland '
  name: 17th IEEE International Conference on Industrial Informatics (INDIN)
  start_date: 2019-07-22
corporate_editor:
- Aalto University, Finland
- Tampere University, Finland
- Finnish Society of Automation, Finland
date_created: 2025-04-16T06:29:04Z
date_updated: 2025-06-26T13:38:06Z
department:
- _id: DEP5023
doi: 10.1109/indin41052.2019.8972251
keyword:
- probabilistic graphical model
- causal model
- alarm flood reduction
- Bayesian network
- Markov chain
- restricted boltzmann machine
- automata
language:
- iso: eng
page: 1285-1290
place: '[Piscataway, NJ]'
publication: 2019 IEEE 17th International Conference on Industrial Informatics (INDIN)
publication_identifier:
  eisbn:
  - 978-1-7281-2927-3
  isbn:
  - 978-1-7281-2928-0
publication_status: published
publisher: IEEE
status: public
title: Comparison of Different Probabilistic Graphical Models as Causal Models in
  Alarm Flood Reduction
type: conference_editor_article
user_id: '83781'
year: '2019'
...
---
_id: '12808'
abstract:
- lang: eng
  text: Along with the constantly increasing complexity of industrial automation systems,
    machine learning methods have been widely applied to detecting abnormal states
    in such systems. Anomaly detection tasks can be treated as one-class classification
    problems in machine learning. Geometric methods can give an intuitive solution
    to such problems. In this paper, we propose a new geometric structure, oriented
    non-convex hulls, to represent decision boundaries used for one-class classification.
    Based on this geometric structure, a novel boundary based one-class classification
    algorithm is developed to solve the anomaly detection problem. Compared with traditional
    boundary-based approaches such as convex hulls based methods and one-class support
    vector machines, the proposed approach can better reflect the true geometry of
    target data and needs little effort for parameter tuning. The effectiveness of
    this approach is evaluated with artificial and real world data sets to solve the
    anomaly detection problem in Cyber-Physical-Production-Systems (CPPS). The evaluation
    results also show that the proposed approach has higher generality than the used
    baseline algorithms.
article_number: '103301'
author:
- first_name: Peng
  full_name: Li, Peng
  id: '58937'
  last_name: Li
- first_name: Oliver
  full_name: Niggemann, Oliver
  id: '10876'
  last_name: Niggemann
citation:
  ama: Li P, Niggemann O. Non-convex hull based anomaly detection in CPPS. <i>Engineering
    Applications of Artificial Intelligence</i>. 2019;87. doi:<a href="https://doi.org/10.1016/j.engappai.2019.103301">10.1016/j.engappai.2019.103301</a>
  apa: Li, P., &#38; Niggemann, O. (2019). Non-convex hull based anomaly detection
    in CPPS. <i>Engineering Applications of Artificial Intelligence</i>, <i>87</i>,
    Article 103301. <a href="https://doi.org/10.1016/j.engappai.2019.103301">https://doi.org/10.1016/j.engappai.2019.103301</a>
  bjps: <b>Li P and Niggemann O</b> (2019) Non-Convex Hull Based Anomaly Detection
    in CPPS. <i>Engineering Applications of Artificial Intelligence</i> <b>87</b>.
  chicago: Li, Peng, and Oliver Niggemann. “Non-Convex Hull Based Anomaly Detection
    in CPPS.” <i>Engineering Applications of Artificial Intelligence</i> 87 (2019).
    <a href="https://doi.org/10.1016/j.engappai.2019.103301">https://doi.org/10.1016/j.engappai.2019.103301</a>.
  chicago-de: Li, Peng und Oliver Niggemann. 2019. Non-convex hull based anomaly detection
    in CPPS. <i>Engineering Applications of Artificial Intelligence</i> 87. doi:<a
    href="https://doi.org/10.1016/j.engappai.2019.103301">10.1016/j.engappai.2019.103301</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Li, Peng</span> ; <span style="font-variant:small-caps;">Niggemann,
    Oliver</span>: Non-convex hull based anomaly detection in CPPS. In: <i>Engineering
    Applications of Artificial Intelligence</i> Bd. 87. Amsterdam [u.a.], Elsevier
    BV (2019)'
  havard: P. Li, O. Niggemann, Non-convex hull based anomaly detection in CPPS, Engineering
    Applications of Artificial Intelligence. 87 (2019).
  ieee: 'P. Li and O. Niggemann, “Non-convex hull based anomaly detection in CPPS,”
    <i>Engineering Applications of Artificial Intelligence</i>, vol. 87, Art. no.
    103301, 2019, doi: <a href="https://doi.org/10.1016/j.engappai.2019.103301">10.1016/j.engappai.2019.103301</a>.'
  mla: Li, Peng, and Oliver Niggemann. “Non-Convex Hull Based Anomaly Detection in
    CPPS.” <i>Engineering Applications of Artificial Intelligence</i>, vol. 87, 103301,
    2019, <a href="https://doi.org/10.1016/j.engappai.2019.103301">https://doi.org/10.1016/j.engappai.2019.103301</a>.
  short: P. Li, O. Niggemann, Engineering Applications of Artificial Intelligence
    87 (2019).
  ufg: '<b>Li, Peng/Niggemann, Oliver</b>: Non-convex hull based anomaly detection
    in CPPS, in: <i>Engineering Applications of Artificial Intelligence</i> 87 (2019).'
  van: Li P, Niggemann O. Non-convex hull based anomaly detection in CPPS. Engineering
    Applications of Artificial Intelligence. 2019;87.
date_created: 2025-04-16T09:51:12Z
date_updated: 2025-06-26T13:34:10Z
department:
- _id: DEP5023
doi: 10.1016/j.engappai.2019.103301
external_id:
  isi:
  - '000506715100040'
intvolume: '        87'
isi: '1'
keyword:
- One-class classification
- n-dimensional oriented non-convex hull
- Anomaly detection
- CPPS
language:
- iso: eng
place: Amsterdam [u.a.]
publication: Engineering Applications of Artificial Intelligence
publication_identifier:
  eissn:
  - 1873-6769
  issn:
  - 0952-1976
publication_status: published
publisher: Elsevier BV
status: public
title: Non-convex hull based anomaly detection in CPPS
type: scientific_journal_article
user_id: '83781'
volume: 87
year: '2019'
...
---
_id: '12826'
abstract:
- lang: eng
  text: The configuration of current automated production systems is complex and therefore
    time consuming while the market demands an easy setup and adaptability due to
    smaller batch sizes and volatile markets. While there are different concepts in
    research on how to simplify the engineering process by using generic skills or
    capabilities of devices, run-time control is still achieved with proprietary communication
    protocols and commands. The concept in this paper uses skills not only in the
    phase of engineering but also consequently for direct and generic control of field-devices.
    An executable skill-metamodel therefore describes the methodological functionality
    which is implemented by using OPC UA due to its vendor independence as well as
    built-in services and information model. The implementation uses client/server-based
    OPC UA and the pub/sub pattern to prepare for a deterministic real-time control
    in conjunction with TSN, which is required by industrial automation.
author:
- first_name: Patrick
  full_name: Zimmermann, Patrick
  last_name: Zimmermann
- first_name: Etienne
  full_name: Axmann, Etienne
  last_name: Axmann
- first_name: Benjamin
  full_name: Brandenbourger, Benjamin
  last_name: Brandenbourger
- first_name: Kirill
  full_name: Dorofeev, Kirill
  last_name: Dorofeev
- first_name: Andre
  full_name: Mankowski, Andre
  id: '51482'
  last_name: Mankowski
- first_name: Paulo
  full_name: Zanini, Paulo
  last_name: Zanini
citation:
  ama: Zimmermann P, Axmann E, Brandenbourger B, Dorofeev K, Mankowski A, Zanini P.
    <i>Skill-Based Engineering and Control on Field-Device-Level with OPC UA</i>.
    (IEEE International Conference on Emerging Technologies and Factory Automation
    , Institute of Electrical and Electronics Engineers, Universidad de Zaragoza ,
    IEEE Industrial Electronics Society , eds.). IEEE; 2019:1101-1108. doi:<a href="https://doi.org/10.1109/etfa.2019.8869473">10.1109/etfa.2019.8869473</a>
  apa: Zimmermann, P., Axmann, E., Brandenbourger, B., Dorofeev, K., Mankowski, A.,
    &#38; Zanini, P. (2019). Skill-based Engineering and Control on Field-Device-Level
    with OPC UA. In IEEE International Conference on Emerging Technologies and Factory
    Automation , Institute of Electrical and Electronics Engineers, Universidad de
    Zaragoza , &#38; IEEE Industrial Electronics Society  (Eds.), <i>24th IEEE International
    Conference on Emerging Technologies and Factory Automation (ETFA)</i> (pp. 1101–1108).
    IEEE. <a href="https://doi.org/10.1109/etfa.2019.8869473">https://doi.org/10.1109/etfa.2019.8869473</a>
  bjps: '<b>Zimmermann P <i>et al.</i></b> (2019) <i>Skill-Based Engineering and Control
    on Field-Device-Level with OPC UA</i>, IEEE International Conference on Emerging
    Technologies and Factory Automation  et al. (eds). [Piscataway, NJ]: IEEE.'
  chicago: 'Zimmermann, Patrick, Etienne Axmann, Benjamin Brandenbourger, Kirill Dorofeev,
    Andre Mankowski, and Paulo Zanini. <i>Skill-Based Engineering and Control on Field-Device-Level
    with OPC UA</i>. Edited by IEEE International Conference on Emerging Technologies
    and Factory Automation , Institute of Electrical and Electronics Engineers, Universidad
    de Zaragoza , and IEEE Industrial Electronics Society . <i>24th IEEE International
    Conference on Emerging Technologies and Factory Automation (ETFA)</i>. IEEE International
    Conference on Emerging Technologies and Factory Automation-ETFA. [Piscataway,
    NJ]: IEEE, 2019. <a href="https://doi.org/10.1109/etfa.2019.8869473">https://doi.org/10.1109/etfa.2019.8869473</a>.'
  chicago-de: 'Zimmermann, Patrick, Etienne Axmann, Benjamin Brandenbourger, Kirill
    Dorofeev, Andre Mankowski und Paulo Zanini. 2019. <i>Skill-based Engineering and
    Control on Field-Device-Level with OPC UA</i>. Hg. von IEEE International Conference
    on Emerging Technologies and Factory Automation , Institute of Electrical and
    Electronics Engineers, Universidad de Zaragoza , und IEEE Industrial Electronics
    Society . <i>24th IEEE International Conference on Emerging Technologies and Factory
    Automation (ETFA)</i>. IEEE International Conference on Emerging Technologies
    and Factory Automation-ETFA. [Piscataway, NJ]: IEEE. doi:<a href="https://doi.org/10.1109/etfa.2019.8869473">10.1109/etfa.2019.8869473</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Zimmermann, Patrick</span>
    ; <span style="font-variant:small-caps;">Axmann, Etienne</span> ; <span style="font-variant:small-caps;">Brandenbourger,
    Benjamin</span> ; <span style="font-variant:small-caps;">Dorofeev, Kirill</span>
    ; <span style="font-variant:small-caps;">Mankowski, Andre</span> ; <span style="font-variant:small-caps;">Zanini,
    Paulo</span> ; <span style="font-variant:small-caps;">IEEE International Conference
    on Emerging Technologies and Factory Automation </span> ; <span style="font-variant:small-caps;">Institute
    of Electrical and Electronics Engineers</span> ; <span style="font-variant:small-caps;">Universidad
    de Zaragoza </span> ; <span style="font-variant:small-caps;">IEEE Industrial Electronics
    Society </span> (Hrsg.): <i>Skill-based Engineering and Control on Field-Device-Level
    with OPC UA</i>, <i>IEEE International Conference on Emerging Technologies and
    Factory Automation-ETFA</i>. [Piscataway, NJ] : IEEE, 2019'
  havard: P. Zimmermann, E. Axmann, B. Brandenbourger, K. Dorofeev, A. Mankowski,
    P. Zanini, Skill-based Engineering and Control on Field-Device-Level with OPC
    UA, IEEE, [Piscataway, NJ], 2019.
  ieee: 'P. Zimmermann, E. Axmann, B. Brandenbourger, K. Dorofeev, A. Mankowski, and
    P. Zanini, <i>Skill-based Engineering and Control on Field-Device-Level with OPC
    UA</i>. [Piscataway, NJ]: IEEE, 2019, pp. 1101–1108. doi: <a href="https://doi.org/10.1109/etfa.2019.8869473">10.1109/etfa.2019.8869473</a>.'
  mla: Zimmermann, Patrick, et al. “Skill-Based Engineering and Control on Field-Device-Level
    with OPC UA.” <i>24th IEEE International Conference on Emerging Technologies and
    Factory Automation (ETFA)</i>, edited by IEEE International Conference on Emerging
    Technologies and Factory Automation  et al., IEEE, 2019, pp. 1101–08, <a href="https://doi.org/10.1109/etfa.2019.8869473">https://doi.org/10.1109/etfa.2019.8869473</a>.
  short: P. Zimmermann, E. Axmann, B. Brandenbourger, K. Dorofeev, A. Mankowski, P.
    Zanini, Skill-Based Engineering and Control on Field-Device-Level with OPC UA,
    IEEE, [Piscataway, NJ], 2019.
  ufg: '<b>Zimmermann, Patrick u. a.</b>: Skill-based Engineering and Control on Field-Device-Level
    with OPC UA, hg. von IEEE International Conference on Emerging Technologies and
    Factory Automation  u. a., [Piscataway, NJ] 2019 (IEEE International Conference
    on Emerging Technologies and Factory Automation-ETFA).'
  van: 'Zimmermann P, Axmann E, Brandenbourger B, Dorofeev K, Mankowski A, Zanini
    P. Skill-based Engineering and Control on Field-Device-Level with OPC UA. IEEE
    International Conference on Emerging Technologies and Factory Automation , Institute
    of Electrical and Electronics Engineers, Universidad de Zaragoza , IEEE Industrial
    Electronics Society , editors. 24th IEEE International Conference on Emerging
    Technologies and Factory Automation (ETFA). [Piscataway, NJ]: IEEE; 2019. (IEEE
    International Conference on Emerging Technologies and Factory Automation-ETFA).'
conference:
  end_date: 201-09-13
  location: Zaragoza, SPAIN
  name: 24th IEEE International Conference on Emerging Technologies and Factory Automation
    (ETFA)
  start_date: 2019-09-10
corporate_editor:
- 'IEEE International Conference on Emerging Technologies and Factory Automation '
- Institute of Electrical and Electronics Engineers
- 'Universidad de Zaragoza '
- 'IEEE Industrial Electronics Society '
date_created: 2025-04-22T13:52:53Z
date_updated: 2025-06-26T13:27:46Z
department:
- _id: DEP5023
doi: 10.1109/etfa.2019.8869473
keyword:
- OPC UA
- Skills
- Capabilities
- Engineering
- Field-Device
- Interoperability
- Control
language:
- iso: eng
page: 1101-1108
place: '[Piscataway, NJ]'
publication: 24th IEEE International Conference on Emerging Technologies and Factory
  Automation (ETFA)
publication_identifier:
  eisbn:
  - 978-1-7281-0302-0
  eissn:
  - 1946-0759
  isbn:
  - 978-1-7281-0303-7
  issn:
  - 1946-0740
publication_status: published
publisher: IEEE
series_title: IEEE International Conference on Emerging Technologies and Factory Automation-ETFA
status: public
title: Skill-based Engineering and Control on Field-Device-Level with OPC UA
type: conference_editor_article
user_id: '83781'
year: '2019'
...
---
_id: '12834'
abstract:
- lang: eng
  text: In the context of Industry 4.0, extensive deployment and application of advanced
    manufacturing equipment and various sensors is leading to a growing demand for
    data exchange between different devices. In smart factories, network transmission
    has multiprotocol features of wired/wireless communication, and different data
    flows have different real-time requirements. In this article, a heterogeneous
    network architecture based on software-defined network is proposed for realizing
    cross-network flexible forwarding of multisource manufacturing data and optimized
    utilization of network resources. Subsequently, the mechanism of cross-network
    fusion and scheduling (CNFS) is analyzed from the perspective of high dynamic
    characteristics and different delay requirements of data flows. Based on this
    analysis, a route-aware data flow dynamic reconstruction algorithm is proposed.
    The proposed algorithm improves the efficiency of manufacturing data cross-network
    fusion, especially for multivariety and small-batch intelligent manufacturing
    systems. Furthermore, for meeting the bandwidth requirements of different delay
    flows, a delay-sensitive network bandwidth scheduling algorithm is proposed. Finally,
    the effectiveness of the proposed CNFS mechanism is verified using a candy packaging
    intelligent production line prototype platform.
author:
- first_name: Jiafu
  full_name: Wan, Jiafu
  last_name: Wan
- first_name: Jun
  full_name: Yang, Jun
  last_name: Yang
- first_name: Shiyong
  full_name: Wang, Shiyong
  last_name: Wang
- first_name: Di
  full_name: Li, Di
  last_name: Li
- first_name: Peng
  full_name: Li, Peng
  id: '58937'
  last_name: Li
- first_name: Min
  full_name: Xia, Min
  last_name: Xia
citation:
  ama: Wan J, Yang J, Wang S, Li D, Li P, Xia M. Cross-Network Fusion and Scheduling
    for Heterogeneous Networks in Smart Factory. <i>IEEE Transactions on Industrial
    Informatics</i>. 2019;16(9):6059-6068. doi:<a href="https://doi.org/10.1109/tii.2019.2952669">10.1109/tii.2019.2952669</a>
  apa: Wan, J., Yang, J., Wang, S., Li, D., Li, P., &#38; Xia, M. (2019). Cross-Network
    Fusion and Scheduling for Heterogeneous Networks in Smart Factory. <i>IEEE Transactions
    on Industrial Informatics</i>, <i>16</i>(9), 6059–6068. <a href="https://doi.org/10.1109/tii.2019.2952669">https://doi.org/10.1109/tii.2019.2952669</a>
  bjps: <b>Wan J <i>et al.</i></b> (2019) Cross-Network Fusion and Scheduling for
    Heterogeneous Networks in Smart Factory. <i>IEEE Transactions on Industrial Informatics</i>
    <b>16</b>, 6059–6068.
  chicago: 'Wan, Jiafu, Jun Yang, Shiyong Wang, Di Li, Peng Li, and Min Xia. “Cross-Network
    Fusion and Scheduling for Heterogeneous Networks in Smart Factory.” <i>IEEE Transactions
    on Industrial Informatics</i> 16, no. 9 (2019): 6059–68. <a href="https://doi.org/10.1109/tii.2019.2952669">https://doi.org/10.1109/tii.2019.2952669</a>.'
  chicago-de: 'Wan, Jiafu, Jun Yang, Shiyong Wang, Di Li, Peng Li und Min Xia. 2019.
    Cross-Network Fusion and Scheduling for Heterogeneous Networks in Smart Factory.
    <i>IEEE Transactions on Industrial Informatics</i> 16, Nr. 9: 6059–6068. doi:<a
    href="https://doi.org/10.1109/tii.2019.2952669">10.1109/tii.2019.2952669</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Wan, Jiafu</span> ; <span style="font-variant:small-caps;">Yang,
    Jun</span> ; <span style="font-variant:small-caps;">Wang, Shiyong</span> ; <span
    style="font-variant:small-caps;">Li, Di</span> ; <span style="font-variant:small-caps;">Li,
    Peng</span> ; <span style="font-variant:small-caps;">Xia, Min</span>: Cross-Network
    Fusion and Scheduling for Heterogeneous Networks in Smart Factory. In: <i>IEEE
    Transactions on Industrial Informatics</i> Bd. 16. New York, NY, Institute of
    Electrical and Electronics Engineers (IEEE) (2019), Nr. 9, S. 6059–6068'
  havard: J. Wan, J. Yang, S. Wang, D. Li, P. Li, M. Xia, Cross-Network Fusion and
    Scheduling for Heterogeneous Networks in Smart Factory, IEEE Transactions on Industrial
    Informatics. 16 (2019) 6059–6068.
  ieee: 'J. Wan, J. Yang, S. Wang, D. Li, P. Li, and M. Xia, “Cross-Network Fusion
    and Scheduling for Heterogeneous Networks in Smart Factory,” <i>IEEE Transactions
    on Industrial Informatics</i>, vol. 16, no. 9, pp. 6059–6068, 2019, doi: <a href="https://doi.org/10.1109/tii.2019.2952669">10.1109/tii.2019.2952669</a>.'
  mla: Wan, Jiafu, et al. “Cross-Network Fusion and Scheduling for Heterogeneous Networks
    in Smart Factory.” <i>IEEE Transactions on Industrial Informatics</i>, vol. 16,
    no. 9, 2019, pp. 6059–68, <a href="https://doi.org/10.1109/tii.2019.2952669">https://doi.org/10.1109/tii.2019.2952669</a>.
  short: J. Wan, J. Yang, S. Wang, D. Li, P. Li, M. Xia, IEEE Transactions on Industrial
    Informatics 16 (2019) 6059–6068.
  ufg: '<b>Wan, Jiafu u. a.</b>: Cross-Network Fusion and Scheduling for Heterogeneous
    Networks in Smart Factory, in: <i>IEEE Transactions on Industrial Informatics</i>
    16 (2019), H. 9,  S. 6059–6068.'
  van: Wan J, Yang J, Wang S, Li D, Li P, Xia M. Cross-Network Fusion and Scheduling
    for Heterogeneous Networks in Smart Factory. IEEE Transactions on Industrial Informatics.
    2019;16(9):6059–68.
date_created: 2025-04-23T08:35:16Z
date_updated: 2025-06-26T13:26:20Z
department:
- _id: DEP5023
doi: 10.1109/tii.2019.2952669
external_id:
  isi:
  - '000542966300043'
intvolume: '        16'
isi: '1'
issue: '9'
keyword:
- Heterogeneous networks
- Real-time systems
- Bandwidth
- Job shop scheduling
- Smart manufacturing
- Computer architecture
- Cross-network fusion
- heterogeneous networks
- network resource
language:
- iso: eng
page: 6059-6068
place: New York, NY
publication: IEEE Transactions on Industrial Informatics
publication_identifier:
  eissn:
  - 1941-0050
  issn:
  - 1551-3203
publication_status: published
publisher: Institute of Electrical and Electronics Engineers (IEEE)
status: public
title: Cross-Network Fusion and Scheduling for Heterogeneous Networks in Smart Factory
type: scientific_journal_article
user_id: '83781'
volume: 16
year: '2019'
...
---
_id: '12965'
abstract:
- lang: eng
  text: "The Bacillus (B.) cereus group consists of nine recognized species which
    are present worldwide. B. cereus play an important role in food-borne diseases
    by producing different toxins. Yet, only a small percentage of B. cereus strains
    are able to produce the heat stable cereulide, the causative agent of emetic food
    poisoning. To minimize the entry of emetic B. cereus into the food chain, food
    business operators are dependent on efficient and reliable methods enabling the
    differentiation between emetic and non-emetic strains.\r\nCurrently, only time-consuming
    cell bioassays, molecular methods and tandem mass spectrometry are available for
    this purpose. Thus, the aim of the present study was to establish a fast and reliable
    method for the differentiation between emetic/non-emetic strains by MALDI-TOF
    MS. Selected strains/isolates of the B. cereus group as well as other Bacillus
    spp. (total n = 121) were cultured on sheep blood agar for 48 h before analysis.\r\nSubsequently,
    the cultures were directly analyzed by MALDI-TOF MS without prior extraction steps.
    The samples were measured in the mass range of m/z 800–1800 Da. Using ClinProTools
    3.0 statistical software and Flex analysis software (Bruker Daltonics GmbH, Bremen,
    Germany), a differentiation between emetic/non-emetic isolates was possible with
    a rate of correct identification of 99.1% by means of the evaluation of two specific
    biomarkers (m/z 1171 and 1187 Da)."
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Christoph
  full_name: Gottschalk, Christoph
  last_name: Gottschalk
- first_name: Richard
  full_name: Dietrich, Richard
  last_name: Dietrich
- first_name: Erwin
  full_name: Märtlbauer, Erwin
  last_name: Märtlbauer
- first_name: Manfred
  full_name: Gareis, Manfred
  last_name: Gareis
citation:
  ama: Ulrich S, Gottschalk C, Dietrich R, Märtlbauer E, Gareis M. Identification
    of cereulide producing Bacillus cereus by MALDI-TOF MS. <i>Food Microbiology</i>.
    2019;82:75-81. doi:<a href="https://doi.org/10.1016/j.fm.2019.01.012">10.1016/j.fm.2019.01.012</a>
  apa: Ulrich, S., Gottschalk, C., Dietrich, R., Märtlbauer, E., &#38; Gareis, M.
    (2019). Identification of cereulide producing Bacillus cereus by MALDI-TOF MS.
    <i>Food Microbiology</i>, <i>82</i>, 75–81. <a href="https://doi.org/10.1016/j.fm.2019.01.012">https://doi.org/10.1016/j.fm.2019.01.012</a>
  bjps: <b>Ulrich S <i>et al.</i></b> (2019) Identification of Cereulide Producing
    Bacillus Cereus by MALDI-TOF MS. <i>Food Microbiology</i> <b>82</b>, 75–81.
  chicago: 'Ulrich, Sebastian, Christoph Gottschalk, Richard Dietrich, Erwin Märtlbauer,
    and Manfred Gareis. “Identification of Cereulide Producing Bacillus Cereus by
    MALDI-TOF MS.” <i>Food Microbiology</i> 82 (2019): 75–81. <a href="https://doi.org/10.1016/j.fm.2019.01.012">https://doi.org/10.1016/j.fm.2019.01.012</a>.'
  chicago-de: 'Ulrich, Sebastian, Christoph Gottschalk, Richard Dietrich, Erwin Märtlbauer
    und Manfred Gareis. 2019. Identification of cereulide producing Bacillus cereus
    by MALDI-TOF MS. <i>Food Microbiology</i> 82: 75–81. doi:<a href="https://doi.org/10.1016/j.fm.2019.01.012">10.1016/j.fm.2019.01.012</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Ulrich, Sebastian</span> ;
    <span style="font-variant:small-caps;">Gottschalk, Christoph</span> ; <span style="font-variant:small-caps;">Dietrich,
    Richard</span> ; <span style="font-variant:small-caps;">Märtlbauer, Erwin</span>
    ; <span style="font-variant:small-caps;">Gareis, Manfred</span>: Identification
    of cereulide producing Bacillus cereus by MALDI-TOF MS. In: <i>Food Microbiology</i>
    Bd. 82. London, Academic Press  (2019), S. 75–81'
  havard: S. Ulrich, C. Gottschalk, R. Dietrich, E. Märtlbauer, M. Gareis, Identification
    of cereulide producing Bacillus cereus by MALDI-TOF MS, Food Microbiology. 82
    (2019) 75–81.
  ieee: 'S. Ulrich, C. Gottschalk, R. Dietrich, E. Märtlbauer, and M. Gareis, “Identification
    of cereulide producing Bacillus cereus by MALDI-TOF MS,” <i>Food Microbiology</i>,
    vol. 82, pp. 75–81, 2019, doi: <a href="https://doi.org/10.1016/j.fm.2019.01.012">10.1016/j.fm.2019.01.012</a>.'
  mla: Ulrich, Sebastian, et al. “Identification of Cereulide Producing Bacillus Cereus
    by MALDI-TOF MS.” <i>Food Microbiology</i>, vol. 82, 2019, pp. 75–81, <a href="https://doi.org/10.1016/j.fm.2019.01.012">https://doi.org/10.1016/j.fm.2019.01.012</a>.
  short: S. Ulrich, C. Gottschalk, R. Dietrich, E. Märtlbauer, M. Gareis, Food Microbiology
    82 (2019) 75–81.
  ufg: '<b>Ulrich, Sebastian u. a.</b>: Identification of cereulide producing Bacillus
    cereus by MALDI-TOF MS, in: <i>Food Microbiology</i> 82 (2019),  S. 75–81.'
  van: Ulrich S, Gottschalk C, Dietrich R, Märtlbauer E, Gareis M. Identification
    of cereulide producing Bacillus cereus by MALDI-TOF MS. Food Microbiology. 2019;82:75–81.
date_created: 2025-06-15T10:18:20Z
date_updated: 2025-06-18T11:16:35Z
department:
- _id: DEP4010
doi: 10.1016/j.fm.2019.01.012
extern: '1'
intvolume: '        82'
keyword:
- MALDI-TOF MS
- Bacillus cereus
- Cereulide
- Food intoxication
language:
- iso: eng
page: 75-81
place: London
publication: Food Microbiology
publication_identifier:
  eissn:
  - 1095-9998
  issn:
  - 0740-0020
publication_status: published
publisher: 'Academic Press '
quality_controlled: '1'
status: public
title: Identification of cereulide producing Bacillus cereus by MALDI-TOF MS
type: scientific_journal_article
user_id: '83781'
volume: 82
year: '2019'
...
---
_id: '12966'
abstract:
- lang: eng
  text: 'The fungus Stachybotrys (S.) chartarum was isolated from culinary herbs,
    damp building materials, and improperly stored animal forage. Two distinct chemotypes
    of the fungus were described that produced either high-cytotoxic macrocyclic trichothecenes
    (S type) or low-cytotoxic atranones (A type). Recently, two distinct gene clusters
    were described that were found to be necessary for the biosynthesis of either
    macrocyclic trichothecenes (21 SAT (Satratoxin) genes) or atranones (14 ATR (Atranone)
    genes). In the current study, PCR primers were designed to detect SAT and ATR
    genes in 19 S. chartarum chemotype S and eight S. chartarum chemotype A strains.
    Our analysis revealed the existence of three different genotypes: satratoxin-producing
    strains that harbored all SAT genes but lacked the ATR gene cluster (genotype
    S), non-satratoxin-producing strains that possessed the ATR genes but lacked SAT
    genes (genotype A), and a hitherto undescribed hybrid genotype among non-satratoxin-producing
    strains that harbored all ATR genes and an incomplete set of SAT genes (genotype
    H). In order to improve the discrimination of genotypes, a triplex PCR assay was
    developed and applied for the analysis of S. chartarum and S. chlorohalonata cultures.
    The results show that genes for macrocyclic trichothecenes and atranones are not
    mutually exclusive in S. chartarum. Correlation of the new genotype-based concept
    with mycotoxin production data shows also that macrocyclic trichothecenes are
    exclusively produced by S. chartarum genotype S strains.'
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Ludwig
  full_name: Niessen, Ludwig
  last_name: Niessen
- first_name: Julia
  full_name: Ekruth, Julia
  last_name: Ekruth
- first_name: Cornelius
  full_name: Schäfer, Cornelius
  last_name: Schäfer
- first_name: Florian
  full_name: Kaltner, Florian
  last_name: Kaltner
- first_name: Christoph
  full_name: Gottschalk, Christoph
  last_name: Gottschalk
citation:
  ama: Ulrich S, Niessen L, Ekruth J, Schäfer C, Kaltner F, Gottschalk C. Truncated
    satratoxin gene clusters in selected isolates of the atranone chemotype of Stachybotrys
    chartarum (Ehrenb.) S. Hughes. <i>Mycotoxin Research</i>. 2019;36(1):83-91. doi:<a
    href="https://doi.org/10.1007/s12550-019-00371-x">10.1007/s12550-019-00371-x</a>
  apa: Ulrich, S., Niessen, L., Ekruth, J., Schäfer, C., Kaltner, F., &#38; Gottschalk,
    C. (2019). Truncated satratoxin gene clusters in selected isolates of the atranone
    chemotype of Stachybotrys chartarum (Ehrenb.) S. Hughes. <i>Mycotoxin Research</i>,
    <i>36</i>(1), 83–91. <a href="https://doi.org/10.1007/s12550-019-00371-x">https://doi.org/10.1007/s12550-019-00371-x</a>
  bjps: <b>Ulrich S <i>et al.</i></b> (2019) Truncated Satratoxin Gene Clusters in
    Selected Isolates of the Atranone Chemotype of Stachybotrys Chartarum (Ehrenb.)
    S. Hughes. <i>Mycotoxin Research</i> <b>36</b>, 83–91.
  chicago: 'Ulrich, Sebastian, Ludwig Niessen, Julia Ekruth, Cornelius Schäfer, Florian
    Kaltner, and Christoph Gottschalk. “Truncated Satratoxin Gene Clusters in Selected
    Isolates of the Atranone Chemotype of Stachybotrys Chartarum (Ehrenb.) S. Hughes.”
    <i>Mycotoxin Research</i> 36, no. 1 (2019): 83–91. <a href="https://doi.org/10.1007/s12550-019-00371-x">https://doi.org/10.1007/s12550-019-00371-x</a>.'
  chicago-de: 'Ulrich, Sebastian, Ludwig Niessen, Julia Ekruth, Cornelius Schäfer,
    Florian Kaltner und Christoph Gottschalk. 2019. Truncated satratoxin gene clusters
    in selected isolates of the atranone chemotype of Stachybotrys chartarum (Ehrenb.)
    S. Hughes. <i>Mycotoxin Research</i> 36, Nr. 1: 83–91. doi:<a href="https://doi.org/10.1007/s12550-019-00371-x">10.1007/s12550-019-00371-x</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Ulrich, Sebastian</span> ;
    <span style="font-variant:small-caps;">Niessen, Ludwig</span> ; <span style="font-variant:small-caps;">Ekruth,
    Julia</span> ; <span style="font-variant:small-caps;">Schäfer, Cornelius</span>
    ; <span style="font-variant:small-caps;">Kaltner, Florian</span> ; <span style="font-variant:small-caps;">Gottschalk,
    Christoph</span>: Truncated satratoxin gene clusters in selected isolates of the
    atranone chemotype of Stachybotrys chartarum (Ehrenb.) S. Hughes. In: <i>Mycotoxin
    Research</i> Bd. 36. Berlin ; Heidelberg, Springer (2019), Nr. 1, S. 83–91'
  havard: S. Ulrich, L. Niessen, J. Ekruth, C. Schäfer, F. Kaltner, C. Gottschalk,
    Truncated satratoxin gene clusters in selected isolates of the atranone chemotype
    of Stachybotrys chartarum (Ehrenb.) S. Hughes, Mycotoxin Research. 36 (2019) 83–91.
  ieee: 'S. Ulrich, L. Niessen, J. Ekruth, C. Schäfer, F. Kaltner, and C. Gottschalk,
    “Truncated satratoxin gene clusters in selected isolates of the atranone chemotype
    of Stachybotrys chartarum (Ehrenb.) S. Hughes,” <i>Mycotoxin Research</i>, vol.
    36, no. 1, pp. 83–91, 2019, doi: <a href="https://doi.org/10.1007/s12550-019-00371-x">10.1007/s12550-019-00371-x</a>.'
  mla: Ulrich, Sebastian, et al. “Truncated Satratoxin Gene Clusters in Selected Isolates
    of the Atranone Chemotype of Stachybotrys Chartarum (Ehrenb.) S. Hughes.” <i>Mycotoxin
    Research</i>, vol. 36, no. 1, 2019, pp. 83–91, <a href="https://doi.org/10.1007/s12550-019-00371-x">https://doi.org/10.1007/s12550-019-00371-x</a>.
  short: S. Ulrich, L. Niessen, J. Ekruth, C. Schäfer, F. Kaltner, C. Gottschalk,
    Mycotoxin Research 36 (2019) 83–91.
  ufg: '<b>Ulrich, Sebastian u. a.</b>: Truncated satratoxin gene clusters in selected
    isolates of the atranone chemotype of Stachybotrys chartarum (Ehrenb.) S. Hughes,
    in: <i>Mycotoxin Research</i> 36 (2019), H. 1,  S. 83–91.'
  van: Ulrich S, Niessen L, Ekruth J, Schäfer C, Kaltner F, Gottschalk C. Truncated
    satratoxin gene clusters in selected isolates of the atranone chemotype of Stachybotrys
    chartarum (Ehrenb.) S. Hughes. Mycotoxin Research. 2019;36(1):83–91.
date_created: 2025-06-15T10:19:53Z
date_updated: 2025-06-18T11:20:11Z
department:
- _id: DEP4010
doi: 10.1007/s12550-019-00371-x
extern: '1'
intvolume: '        36'
issue: '1'
keyword:
- Acetyltransferases
- Chlamydomonas reinhardtii
- Fungal Genes
- Fungal genetics
- Fungal genomics
- Saccharomyces cerevisiae
language:
- iso: eng
page: 83-91
place: Berlin ; Heidelberg
publication: Mycotoxin Research
publication_identifier:
  eissn:
  - 1867-1632
  issn:
  - 0178-7888
publication_status: published
publisher: Springer
quality_controlled: '1'
status: public
title: Truncated satratoxin gene clusters in selected isolates of the atranone chemotype
  of Stachybotrys chartarum (Ehrenb.) S. Hughes
type: scientific_journal_article
user_id: '83781'
volume: 36
year: '2019'
...
---
_id: '12967'
abstract:
- lang: eng
  text: "Objectives\r\nTo evaluate matrix-assisted laser desorption ionisation time
    of flight mass spectrometry (MALDI-TOF MS) combined with the Sepsityper kit (Bruker
    Daltoniks GmbH, Bremen) for the direct detection of bacterial species from inoculated
    blood cultures from dogs and cats.\r\nMaterials and Methods\r\nCanine and feline
    blood samples were inoculated with typical sepsis-causing bacteria such as Staphylococcus
    intermedius, Staphylococcus aureus, Streptococcus canis, Enterococcus faecalis,
    Escherichia coli and Pseudomonas aeruginosa at two distinct concentrations (each
    in triplicate), resulting in 72 blood culture bottles incubated at 37°C. Samples
    were comparatively analysed with MALDI-TOF MS after preparation with the Sepsityper
    kit and also by standard bacteriology (culturing and biochemical characterisation).\r\nResults\r\nBacterial
    species identified from agar plates and by MALDI-TOF MS from blood culture bottles
    were identical for all samples. The MALDI Biotyper software (Bruker Daltoniks)
    correctly identified all bacterial strains from inoculated canine and feline blood
    with analysis indicating very good precision.\r\nClinical Significance\r\nMALDI-TOF
    MS analysis combined with the Sepsityper kit is a reliable tool for a quick detection
    of veterinary-relevant bacterial species directly from blood culture bottles.
    This approach could reduce the time for identification of critical species to
    only 24 hours."
author:
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: C.
  full_name: Gottschalk, C.
  last_name: Gottschalk
- first_name: R. Kk
  full_name: Straubinger, R. Kk
  last_name: Straubinger
- first_name: K.
  full_name: Schwaiger, K.
  last_name: Schwaiger
- first_name: R.
  full_name: Dörfelt, R.
  last_name: Dörfelt
citation:
  ama: Ulrich S, Gottschalk C, Straubinger RK, Schwaiger K, Dörfelt R. Acceleration
    of the identification of sepsis‐inducing bacteria in cultures of dog and cat blood.
    <i>Journal of Small Animal Practice</i>. 2019;61(1):42-45. doi:<a href="https://doi.org/10.1111/jsap.13056">10.1111/jsap.13056</a>
  apa: Ulrich, S., Gottschalk, C., Straubinger, R. K., Schwaiger, K., &#38; Dörfelt,
    R. (2019). Acceleration of the identification of sepsis‐inducing bacteria in cultures
    of dog and cat blood. <i>Journal of Small Animal Practice</i>, <i>61</i>(1), 42–45.
    <a href="https://doi.org/10.1111/jsap.13056">https://doi.org/10.1111/jsap.13056</a>
  bjps: <b>Ulrich S <i>et al.</i></b> (2019) Acceleration of the Identification of
    Sepsis‐inducing Bacteria in Cultures of Dog and Cat Blood. <i>Journal of Small
    Animal Practice</i> <b>61</b>, 42–45.
  chicago: 'Ulrich, Sebastian, C. Gottschalk, R. Kk Straubinger, K. Schwaiger, and
    R. Dörfelt. “Acceleration of the Identification of Sepsis‐inducing Bacteria in
    Cultures of Dog and Cat Blood.” <i>Journal of Small Animal Practice</i> 61, no.
    1 (2019): 42–45. <a href="https://doi.org/10.1111/jsap.13056">https://doi.org/10.1111/jsap.13056</a>.'
  chicago-de: 'Ulrich, Sebastian, C. Gottschalk, R. Kk Straubinger, K. Schwaiger und
    R. Dörfelt. 2019. Acceleration of the identification of sepsis‐inducing bacteria
    in cultures of dog and cat blood. <i>Journal of Small Animal Practice</i> 61,
    Nr. 1: 42–45. doi:<a href="https://doi.org/10.1111/jsap.13056">10.1111/jsap.13056</a>,
    .'
  din1505-2-1: '<span style="font-variant:small-caps;">Ulrich, Sebastian</span> ;
    <span style="font-variant:small-caps;">Gottschalk, C.</span> ; <span style="font-variant:small-caps;">Straubinger,
    R. Kk</span> ; <span style="font-variant:small-caps;">Schwaiger, K.</span> ; <span
    style="font-variant:small-caps;">Dörfelt, R.</span>: Acceleration of the identification
    of sepsis‐inducing bacteria in cultures of dog and cat blood. In: <i>Journal of
    Small Animal Practice</i> Bd. 61. Oxford [u.a.], Wiley-Blackwell (2019), Nr. 1,
    S. 42–45'
  havard: S. Ulrich, C. Gottschalk, R.K. Straubinger, K. Schwaiger, R. Dörfelt, Acceleration
    of the identification of sepsis‐inducing bacteria in cultures of dog and cat blood,
    Journal of Small Animal Practice. 61 (2019) 42–45.
  ieee: 'S. Ulrich, C. Gottschalk, R. K. Straubinger, K. Schwaiger, and R. Dörfelt,
    “Acceleration of the identification of sepsis‐inducing bacteria in cultures of dog
    and cat blood,” <i>Journal of Small Animal Practice</i>, vol. 61, no. 1, pp. 42–45,
    2019, doi: <a href="https://doi.org/10.1111/jsap.13056">10.1111/jsap.13056</a>.'
  mla: Ulrich, Sebastian, et al. “Acceleration of the Identification of Sepsis‐inducing
    Bacteria in Cultures of Dog and Cat Blood.” <i>Journal of Small Animal Practice</i>,
    vol. 61, no. 1, 2019, pp. 42–45, <a href="https://doi.org/10.1111/jsap.13056">https://doi.org/10.1111/jsap.13056</a>.
  short: S. Ulrich, C. Gottschalk, R.K. Straubinger, K. Schwaiger, R. Dörfelt, Journal
    of Small Animal Practice 61 (2019) 42–45.
  ufg: '<b>Ulrich, Sebastian u. a.</b>: Acceleration of the identification of sepsis‐inducing
    bacteria in cultures of dog and cat blood, in: <i>Journal of Small Animal Practice</i>
    61 (2019), H. 1,  S. 42–45.'
  van: Ulrich S, Gottschalk C, Straubinger RK, Schwaiger K, Dörfelt R. Acceleration
    of the identification of sepsis‐inducing bacteria in cultures of dog and cat blood.
    Journal of Small Animal Practice. 2019;61(1):42–5.
date_created: 2025-06-15T10:20:55Z
date_updated: 2025-06-18T11:24:12Z
department:
- _id: DEP4010
doi: 10.1111/jsap.13056
extern: '1'
intvolume: '        61'
issue: '1'
language:
- iso: eng
page: 42-45
place: Oxford [u.a.]
publication: Journal of Small Animal Practice
publication_identifier:
  issn:
  - 0022-4510
  - 1748-5827
publication_status: published
publisher: Wiley-Blackwell
quality_controlled: '1'
status: public
title: Acceleration of the identification of sepsis‐inducing bacteria in cultures
  of dog and cat blood
type: scientific_journal_article
user_id: '83781'
volume: 61
year: '2019'
...
---
_id: '12971'
abstract:
- lang: eng
  text: The genus Stachybotrys produces a broad diversity of secondary metabolites,
    including macrocyclic trichothecenes, atranones, and phenylspirodrimanes. Although
    the class of the phenylspirodrimanes is the major one and consists of a multitude
    of metabolites bearing various structural modifications, few investigations have
    been carried out. Thus, the presented study deals with the quantitative determination
    of several secondary metabolites produced by distinct Stachybotrys species for
    comparison of their metabolite profiles. For that purpose, 15 of the primarily
    produced secondary metabolites were isolated from fungal cultures and structurally
    characterized in order to be used as analytical standards for the development
    of an LC-MS/MS multimethod. The developed method was applied to the analysis of
    micro-scale extracts from 5 different Stachybotrys strains, which were cultured
    on different media. In that process, spontaneous dialdehyde/lactone isomerization
    was observed for some of the isolated secondary metabolites, and novel stachybotrychromenes
    were quantitatively investigated for the first time. The metabolite profiles of
    Stachybotrys species are considerably influenced by time of growth and substrate
    availability, as well as the individual biosynthetic potential of the respective
    species. Regarding the reported adverse effects associated with Stachybotrys growth
    in building environments, combinatory effects of the investigated secondary metabolites
    should be addressed and the role of the phenylspirodrimanes re-evaluated in future
    research.
article_number: '133'
author:
- first_name: Annika
  full_name: Jagels, Annika
  last_name: Jagels
- first_name: Viktoria
  full_name: Lindemann, Viktoria
  last_name: Lindemann
- first_name: Sebastian
  full_name: Ulrich, Sebastian
  id: '85847'
  last_name: Ulrich
  orcid: 0000-0002-4511-9537
- first_name: Christoph
  full_name: Gottschalk, Christoph
  last_name: Gottschalk
- first_name: Benedikt
  full_name: Cramer, Benedikt
  last_name: Cramer
- first_name: Florian
  full_name: Hübner, Florian
  last_name: Hübner
- first_name: Manfred
  full_name: Gareis, Manfred
  last_name: Gareis
- first_name: Hans-Ulrich
  full_name: Humpf, Hans-Ulrich
  last_name: Humpf
citation:
  ama: Jagels A, Lindemann V, Ulrich S, et al. Exploring Secondary Metabolite Profiles
    of Stachybotrys spp. by LC-MS/MS. <i>Toxins</i>. 2019;11(3). doi:<a href="https://doi.org/10.3390/toxins11030133">10.3390/toxins11030133</a>
  apa: Jagels, A., Lindemann, V., Ulrich, S., Gottschalk, C., Cramer, B., Hübner,
    F., Gareis, M., &#38; Humpf, H.-U. (2019). Exploring Secondary Metabolite Profiles
    of Stachybotrys spp. by LC-MS/MS. <i>Toxins</i>, <i>11</i>(3), Article 133. <a
    href="https://doi.org/10.3390/toxins11030133">https://doi.org/10.3390/toxins11030133</a>
  bjps: <b>Jagels A <i>et al.</i></b> (2019) Exploring Secondary Metabolite Profiles
    of Stachybotrys Spp. by LC-MS/MS. <i>Toxins</i> <b>11</b>.
  chicago: Jagels, Annika, Viktoria Lindemann, Sebastian Ulrich, Christoph Gottschalk,
    Benedikt Cramer, Florian Hübner, Manfred Gareis, and Hans-Ulrich Humpf. “Exploring
    Secondary Metabolite Profiles of Stachybotrys Spp. by LC-MS/MS.” <i>Toxins</i>
    11, no. 3 (2019). <a href="https://doi.org/10.3390/toxins11030133">https://doi.org/10.3390/toxins11030133</a>.
  chicago-de: Jagels, Annika, Viktoria Lindemann, Sebastian Ulrich, Christoph Gottschalk,
    Benedikt Cramer, Florian Hübner, Manfred Gareis und Hans-Ulrich Humpf. 2019. Exploring
    Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS. <i>Toxins</i>
    11, Nr. 3. doi:<a href="https://doi.org/10.3390/toxins11030133">10.3390/toxins11030133</a>,
    .
  din1505-2-1: '<span style="font-variant:small-caps;">Jagels, Annika</span> ; <span
    style="font-variant:small-caps;">Lindemann, Viktoria</span> ; <span style="font-variant:small-caps;">Ulrich,
    Sebastian</span> ; <span style="font-variant:small-caps;">Gottschalk, Christoph</span>
    ; <span style="font-variant:small-caps;">Cramer, Benedikt</span> ; <span style="font-variant:small-caps;">Hübner,
    Florian</span> ; <span style="font-variant:small-caps;">Gareis, Manfred</span>
    ; <span style="font-variant:small-caps;">Humpf, Hans-Ulrich</span>: Exploring
    Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS. In: <i>Toxins</i>
    Bd. 11. Basel, MDPI (2019), Nr. 3'
  havard: A. Jagels, V. Lindemann, S. Ulrich, C. Gottschalk, B. Cramer, F. Hübner,
    M. Gareis, H.-U. Humpf, Exploring Secondary Metabolite Profiles of Stachybotrys
    spp. by LC-MS/MS, Toxins. 11 (2019).
  ieee: 'A. Jagels <i>et al.</i>, “Exploring Secondary Metabolite Profiles of Stachybotrys
    spp. by LC-MS/MS,” <i>Toxins</i>, vol. 11, no. 3, Art. no. 133, 2019, doi: <a
    href="https://doi.org/10.3390/toxins11030133">10.3390/toxins11030133</a>.'
  mla: Jagels, Annika, et al. “Exploring Secondary Metabolite Profiles of Stachybotrys
    Spp. by LC-MS/MS.” <i>Toxins</i>, vol. 11, no. 3, 133, 2019, <a href="https://doi.org/10.3390/toxins11030133">https://doi.org/10.3390/toxins11030133</a>.
  short: A. Jagels, V. Lindemann, S. Ulrich, C. Gottschalk, B. Cramer, F. Hübner,
    M. Gareis, H.-U. Humpf, Toxins 11 (2019).
  ufg: '<b>Jagels, Annika u. a.</b>: Exploring Secondary Metabolite Profiles of Stachybotrys
    spp. by LC-MS/MS, in: <i>Toxins</i> 11 (2019), H. 3.'
  van: Jagels A, Lindemann V, Ulrich S, Gottschalk C, Cramer B, Hübner F, et al. Exploring
    Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS. Toxins. 2019;11(3).
date_created: 2025-06-15T10:23:36Z
date_updated: 2025-06-17T14:12:55Z
department:
- _id: DEP4010
doi: 10.3390/toxins11030133
extern: '1'
intvolume: '        11'
issue: '3'
keyword:
- Stachybotrys spp.
- metabolite profiles
- LC-MS/MS
- satratoxins
- phenylspirodrimanes
- stachybotrychromenes
- biosynthetic production
language:
- iso: eng
place: Basel
publication: Toxins
publication_identifier:
  eissn:
  - 2072-6651
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Exploring Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS
type: scientific_journal_article
user_id: '83781'
volume: 11
year: '2019'
...