[{"publication":"Facade Tectonics 2020 World Congress","status":"public","department":[{"_id":"DEP1034"}],"year":2020,"user_id":"15514","conference":{"location":"Los Angeles","start_date":"2020-08-05","end_date":"2020-08-27","name":"Facade Tectonics 2020 World Congress"},"abstract":[{"text":"Urban noise pollution is a major environmental health problem. International organizations are making efforts to prevent health damage due to high levels of noise in cities, but the design of the built environment typically neglects the acoustic impact of architectural projects. Building facades, covering a substantial part of the vertical surfaces of the urban fabric, have a significant effect on the wellbeing of the population and on the environmental impact of buildings. Facade geometries and materials interact with the diversity of sounds in the city composing soundscapes that influence the health, comfort, and productivity of people inside and outside of buildings. This study gives an overview of the elements involved in the composition of the urban soundscape and revises the potential effects of sound-reflective and sound-absorptive facades. With the purpose of exemplifying the integration of acoustic data into facade design processes, a parametric design workflow is developed to experiment with acoustic simulations of a street environment, alternating between sound-reflective and sound-absorptive facades.","lang":"eng"}],"keyword":["acoustics","sustainability","computational design","parametric workflows"],"_id":"5848","date_created":"2021-05-07T09:36:31Z","language":[{"iso":"eng"}],"publication_status":"published","citation":{"chicago-de":"Arztmann, Daniel, Jhosangela Ramirez und Tomas Mena Lozada . 2020. Facade 4.0 – The new digital life-cycle of the building envelope. In: <i>Facade Tectonics 2020 World Congress</i>.","chicago":"Arztmann, Daniel, Jhosangela Ramirez, and Tomas Mena Lozada . “Facade 4.0 – The New Digital Life-Cycle of the Building Envelope.” In <i>Facade Tectonics 2020 World Congress</i>, 2020.","ufg":"<b>Arztmann, Daniel et. al. (2020)</b>: Facade 4.0 – The new digital life-cycle of the building envelope, in: <i>Facade Tectonics 2020 World Congress</i>.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Arztmann, Daniel</span> ; <span style=\"font-variant:small-caps;\">Ramirez, Jhosangela</span> ; <span style=\"font-variant:small-caps;\">Mena Lozada , Tomas</span>: Facade 4.0 – The new digital life-cycle of the building envelope. In: <i>Facade Tectonics 2020 World Congress</i>, 2020","apa":"Arztmann, D., Ramirez, J., &#38; Mena Lozada , T. (2020). Facade 4.0 – The new digital life-cycle of the building envelope. In <i>Facade Tectonics 2020 World Congress</i>. Los Angeles.","mla":"Arztmann, Daniel, et al. “Facade 4.0 – The New Digital Life-Cycle of the Building Envelope.” <i>Facade Tectonics 2020 World Congress</i>, 2020.","bjps":"<b>Arztmann D, Ramirez J and Mena Lozada  T</b> (2020) Facade 4.0 – The New Digital Life-Cycle of the Building Envelope. <i>Facade Tectonics 2020 World Congress</i>.","short":"D. Arztmann, J. Ramirez, T. Mena Lozada , in: Facade Tectonics 2020 World Congress, 2020.","van":"Arztmann D, Ramirez J, Mena Lozada  T. Facade 4.0 – The new digital life-cycle of the building envelope. In: Facade Tectonics 2020 World Congress. 2020.","ama":"Arztmann D, Ramirez J, Mena Lozada  T. Facade 4.0 – The new digital life-cycle of the building envelope. In: <i>Facade Tectonics 2020 World Congress</i>. ; 2020.","ieee":"D. Arztmann, J. Ramirez, and T. Mena Lozada , “Facade 4.0 – The new digital life-cycle of the building envelope,” in <i>Facade Tectonics 2020 World Congress</i>, Los Angeles, 2020.","havard":"D. Arztmann, J. Ramirez, T. Mena Lozada , Facade 4.0 – The new digital life-cycle of the building envelope, in: Facade Tectonics 2020 World Congress, 2020."},"type":"conference","author":[{"first_name":"Daniel","full_name":"Arztmann, Daniel","id":"58805","last_name":"Arztmann"},{"last_name":"Ramirez","id":"76448","full_name":"Ramirez, Jhosangela","first_name":"Jhosangela"},{"last_name":"Mena Lozada ","full_name":"Mena Lozada , Tomas","first_name":"Tomas"}],"title":"Facade 4.0 – The new digital life-cycle of the building envelope","date_updated":"2023-03-15T13:50:02Z"},{"status":"public","user_id":"15514","year":2020,"department":[{"_id":"DEP1034"}],"corporate_editor":["Technischen Hochschule Ostwestfalen-Lippe"],"conference":{"location":"Detmold ( online)","name":"Detmold Conference Weeks 2020 ","start_date":"2020-11-10"},"_id":"5856","place":"Detmold","citation":{"ufg":"<b>Arztmann, Daniel (2020)</b>: Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t, in: Technischen Hochschule Ostwestfalen-Lippe (Hg.): , Detmold.","chicago-de":"Arztmann, Daniel. 2020. Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t. In: , hg. von Technischen Hochschule Ostwestfalen-Lippe. Detmold: Technischen Hochschule Ostwestfalen-Lippe.","short":"D. Arztmann, in: Technischen Hochschule Ostwestfalen-Lippe (Ed.), Technischen Hochschule Ostwestfalen-Lippe, Detmold, 2020.","mla":"Arztmann, Daniel. <i>Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t</i>. Edited by Technischen Hochschule Ostwestfalen-Lippe, Technischen Hochschule Ostwestfalen-Lippe, 2020.","apa":"Arztmann, D. (2020). Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t. In Technischen Hochschule Ostwestfalen-Lippe (Ed.). Presented at the Detmold Conference Weeks 2020 , Detmold: Technischen Hochschule Ostwestfalen-Lippe.","havard":"D. Arztmann, Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t, in: Technischen Hochschule Ostwestfalen-Lippe (Ed.), Technischen Hochschule Ostwestfalen-Lippe, Detmold, 2020.","chicago":"Arztmann, Daniel. “Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t.” edited by Technischen Hochschule Ostwestfalen-Lippe. Detmold: Technischen Hochschule Ostwestfalen-Lippe, 2020.","bjps":"<b>Arztmann D</b> (2020) Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t. In Technischen Hochschule Ostwestfalen-Lippe (ed.). Detmold: Technischen Hochschule Ostwestfalen-Lippe.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Arztmann, Daniel</span>: Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t. In: <span style=\"font-variant:small-caps;\">Technischen Hochschule Ostwestfalen-Lippe</span> (Hrsg.): . Detmold : Technischen Hochschule Ostwestfalen-Lippe, 2020","van":"Arztmann D. Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t. In: Technischen Hochschule Ostwestfalen-Lippe, editor. Detmold: Technischen Hochschule Ostwestfalen-Lippe; 2020.","ama":"Arztmann D. Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t. In: Technischen Hochschule Ostwestfalen-Lippe, ed. Detmold: Technischen Hochschule Ostwestfalen-Lippe; 2020.","ieee":"D. Arztmann, “Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t,” presented at the Detmold Conference Weeks 2020 , Detmold ( online), 2020."},"date_created":"2021-05-07T12:16:14Z","language":[{"iso":"ger"}],"publisher":"Technischen Hochschule Ostwestfalen-Lippe","publication_status":"published","type":"conference_abstract","author":[{"first_name":"Daniel","full_name":"Arztmann, Daniel","id":"58805","last_name":"Arztmann"}],"date_updated":"2023-03-15T13:50:02Z","title":"Moderation der Session „Facade Trends and Innovation“ im Rahmen der Detmold Conference Weeks 2020 (online) an der Technischen Hochschule Ostwestfalen-Lippe, 20.11.2020\t"},{"publication_status":"published","language":[{"iso":"eng"}],"publisher":"Façade Tectonics Institute","date_created":"2021-05-07T12:19:09Z","citation":{"havard":"D. Arztmann, Digital Lifecycle of Building Envelopes : Vortrag, in: Façade Tectonics Institute (Ed.), World Congress 2020 (Online) Des Façade Tectonics Institutes, 19.08.2020, Façade Tectonics Institute, Los Angeles, 2020.","short":"D. Arztmann, in: Façade Tectonics Institute (Ed.), World Congress 2020 (Online) Des Façade Tectonics Institutes, 19.08.2020, Façade Tectonics Institute, Los Angeles, 2020.","apa":"Arztmann, D. (2020). Digital Lifecycle of Building Envelopes : Vortrag. In Façade Tectonics Institute (Ed.), <i>World Congress 2020 (online) des Façade Tectonics Institutes, 19.08.2020</i>. Los Angeles: Façade Tectonics Institute.","mla":"Arztmann, Daniel. “Digital Lifecycle of Building Envelopes : Vortrag.” <i>World Congress 2020 (Online) Des Façade Tectonics Institutes, 19.08.2020</i>, edited by Façade Tectonics Institute, Façade Tectonics Institute, 2020.","ufg":"<b>Arztmann, Daniel (2020)</b>: Digital Lifecycle of Building Envelopes : Vortrag, in: Façade Tectonics Institute (Hg.): <i>World Congress 2020 (online) des Façade Tectonics Institutes, 19.08.2020</i>, Los Angeles.","chicago-de":"Arztmann, Daniel. 2020. Digital Lifecycle of Building Envelopes : Vortrag. In: <i>World Congress 2020 (online) des Façade Tectonics Institutes, 19.08.2020</i>, hg. von Façade Tectonics Institute. Los Angeles: Façade Tectonics Institute.","ieee":"D. Arztmann, “Digital Lifecycle of Building Envelopes : Vortrag,” in <i>World Congress 2020 (online) des Façade Tectonics Institutes, 19.08.2020</i>, Los Angeles, 2020.","ama":"Arztmann D. Digital Lifecycle of Building Envelopes : Vortrag. In: Façade Tectonics Institute, ed. <i>World Congress 2020 (Online) Des Façade Tectonics Institutes, 19.08.2020</i>. Los Angeles: Façade Tectonics Institute; 2020.","van":"Arztmann D. Digital Lifecycle of Building Envelopes : Vortrag. In: Façade Tectonics Institute, editor. World Congress 2020 (online) des Façade Tectonics Institutes, 19082020. Los Angeles: Façade Tectonics Institute; 2020.","bjps":"<b>Arztmann D</b> (2020) Digital Lifecycle of Building Envelopes : Vortrag. In Façade Tectonics Institute (ed.), <i>World Congress 2020 (Online) Des Façade Tectonics Institutes, 19.08.2020</i>. Los Angeles: Façade Tectonics Institute.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Arztmann, Daniel</span>: Digital Lifecycle of Building Envelopes : Vortrag. In: <span style=\"font-variant:small-caps;\">Façade Tectonics Institute</span> (Hrsg.): <i>World Congress 2020 (online) des Façade Tectonics Institutes, 19.08.2020</i>. Los Angeles : Façade Tectonics Institute, 2020","chicago":"Arztmann, Daniel. “Digital Lifecycle of Building Envelopes : Vortrag.” In <i>World Congress 2020 (Online) Des Façade Tectonics Institutes, 19.08.2020</i>, edited by Façade Tectonics Institute. Los Angeles: Façade Tectonics Institute, 2020."},"place":"Los Angeles","type":"conference_abstract","author":[{"id":"58805","last_name":"Arztmann","full_name":"Arztmann, Daniel","first_name":"Daniel"}],"title":"Digital Lifecycle of Building Envelopes : Vortrag","date_updated":"2023-03-15T13:50:02Z","publication":"World Congress 2020 (online) des Façade Tectonics Institutes, 19.08.2020","status":"public","corporate_editor":["Façade Tectonics Institute"],"department":[{"_id":"DEP1034"}],"user_id":"15514","year":2020,"conference":{"location":"Los Angeles","name":"World Congress 2020 (online)  Façade Tectonics Institute","end_date":"2020-08-27","start_date":"2020-08-05"},"_id":"5857"},{"title":"Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020","date_updated":"2023-03-15T13:50:02Z","author":[{"full_name":"Arztmann, Daniel","id":"58805","last_name":"Arztmann","first_name":"Daniel"}],"type":"conference_abstract","publication_status":"published","publisher":"Façade Tectonics Institute","language":[{"iso":"eng"}],"date_created":"2021-05-07T12:22:48Z","citation":{"chicago-de":"Arztmann, Daniel. 2020. Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020. In: , hg. von Façade Tectonics Institute. Los Angeles: Façade Tectonics Institute.","ufg":"<b>Arztmann, Daniel (2020)</b>: Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020, in: Façade Tectonics Institute (Hg.): , Los Angeles.","apa":"Arztmann, D. (2020). Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020. In Façade Tectonics Institute (Ed.). Presented at the World Congress 2020 (online)  Façade Tectonics Institute, Los Angeles: Façade Tectonics Institute.","mla":"Arztmann, Daniel. <i>Moderation Der Session ”Education and Research” Auf Dem World Congress 2020 (Online) Des Façade Tectonics Institutes, 26.08.2020</i>. Edited by Façade Tectonics Institute, Façade Tectonics Institute, 2020.","short":"D. Arztmann, in: Façade Tectonics Institute (Ed.), Façade Tectonics Institute, Los Angeles, 2020.","havard":"D. Arztmann, Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020, in: Façade Tectonics Institute (Ed.), Façade Tectonics Institute, Los Angeles, 2020.","chicago":"Arztmann, Daniel. “Moderation Der Session ”Education and Research” Auf Dem World Congress 2020 (Online) Des Façade Tectonics Institutes, 26.08.2020.” edited by Façade Tectonics Institute. Los Angeles: Façade Tectonics Institute, 2020.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Arztmann, Daniel</span>: Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020. In: <span style=\"font-variant:small-caps;\">Façade Tectonics Institute</span> (Hrsg.): . Los Angeles : Façade Tectonics Institute, 2020","bjps":"<b>Arztmann D</b> (2020) Moderation Der Session ”Education and Research” Auf Dem World Congress 2020 (Online) Des Façade Tectonics Institutes, 26.08.2020. In Façade Tectonics Institute (ed.). Los Angeles: Façade Tectonics Institute.","ama":"Arztmann D. Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020. In: Façade Tectonics Institute, ed. Los Angeles: Façade Tectonics Institute; 2020.","van":"Arztmann D. Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020. In: Façade Tectonics Institute, editor. Los Angeles: Façade Tectonics Institute; 2020.","ieee":"D. Arztmann, “Moderation der Session ”Education and Research” auf dem World Congress 2020 (online) des Façade Tectonics Institutes, 26.08.2020,” presented at the World Congress 2020 (online)  Façade Tectonics Institute, Los Angeles, 2020."},"place":"Los Angeles","_id":"5858","conference":{"end_date":"2020-08-27","start_date":"2020-08-05","name":"World Congress 2020 (online)  Façade Tectonics Institute","location":"Los Angeles"},"corporate_editor":["Façade Tectonics Institute"],"department":[{"_id":"DEP1034"}],"year":2020,"user_id":"15514","status":"public"},{"publication":"Detmold Conference Week","status":"public","department":[{"_id":"DEP1055"},{"_id":"DEP1025"},{"_id":"DEP1028"}],"user_id":"83781","year":"2020","conference":{"end_date":"2020-02-11","start_date":"2020-02-11","name":"Detmold Conference Week","location":"Detmold"},"_id":"5893","language":[{"iso":"eng"}],"date_created":"2021-05-14T08:38:07Z","citation":{"chicago":"Häusler, Axel, Carsten Oldenburg, Christopher Kintrup, Laura Rabea Bremenkamp, Amanda Barbosa Jardim, and Maximilian Müh. “Forum Essigfabrik - Culture Tech Talk 2.” In <i>Detmold Conference Week</i>, 2020.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Häusler, Axel</span> ; <span style=\"font-variant:small-caps;\">Oldenburg, Carsten</span> ; <span style=\"font-variant:small-caps;\">Kintrup, Christopher</span> ; <span style=\"font-variant:small-caps;\">Bremenkamp, Laura Rabea</span> ; <span style=\"font-variant:small-caps;\">Barbosa Jardim, Amanda</span> ; <span style=\"font-variant:small-caps;\">Müh, Maximilian</span>: Forum Essigfabrik - Culture Tech Talk 2. 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In: <i>Detmold Conference Week</i>.","ufg":"<b>Häusler, Axel u. a.</b>: Forum Essigfabrik - Culture Tech Talk 2, in: o. Hg.: Detmold Conference Week, o. O. 2020.","apa":"Häusler, A., Oldenburg, C., Kintrup, C., Bremenkamp, L. R., Barbosa Jardim, A., &#38; Müh, M. (2020). Forum Essigfabrik - Culture Tech Talk 2. <i>Detmold Conference Week</i>. Detmold Conference Week, Detmold.","mla":"Häusler, Axel, et al. “Forum Essigfabrik - Culture Tech Talk 2.” <i>Detmold Conference Week</i>, 2020.","short":"A. Häusler, C. Oldenburg, C. Kintrup, L.R. Bremenkamp, A. Barbosa Jardim, M. Müh, in: Detmold Conference Week, 2020.","havard":"A. Häusler, C. Oldenburg, C. Kintrup, L.R. Bremenkamp, A. Barbosa Jardim, M. Müh, Forum Essigfabrik - Culture Tech Talk 2, in: Detmold Conference Week, 2020."},"type":"conference","author":[{"orcid":"0009-0001-8565-8199","first_name":"Axel","full_name":"Häusler, Axel","id":"61520","last_name":"Häusler"},{"first_name":"Carsten","full_name":"Oldenburg, Carsten","last_name":"Oldenburg","id":"75372"},{"first_name":"Christopher","full_name":"Kintrup, Christopher","last_name":"Kintrup","id":"74454"},{"first_name":"Laura Rabea","full_name":"Bremenkamp, Laura Rabea","id":"74264","last_name":"Bremenkamp"},{"first_name":"Amanda","full_name":"Barbosa Jardim, Amanda","last_name":"Barbosa Jardim","id":"76917"},{"first_name":"Maximilian","full_name":"Müh, Maximilian","last_name":"Müh","id":"74260"}],"title":"Forum Essigfabrik - Culture Tech Talk 2","date_updated":"2024-12-04T12:59:07Z","related_material":{"link":[{"relation":"original","url":"https://www.detmoldconferenceweek.online"}]}},{"_id":"5905","page":"760","year":"2020","user_id":"83778","department":[{"_id":"DEP1055"}],"status":"public","publication":"Atlas of Digital Architecture","related_material":{"link":[{"relation":"confirmation","url":"https://www.atlasofdigitalarchitecture.com/"}]},"date_updated":"2025-09-15T06:34:43Z","doi":"10.1515/9783035620115-017","title":"Model Making","author":[{"first_name":"Hans","last_name":"Sachs","id":"64589","full_name":"Sachs, Hans"},{"first_name":"Milena","full_name":"Stavric, Milena","last_name":"Stavric"}],"type":"book_chapter","publication_identifier":{"eisbn":["9783035620115"],"isbn":["9783035619904"]},"place":"Basel","citation":{"din1505-2-1":"<span style=\"font-variant:small-caps;\">Sachs, Hans</span> ; <span style=\"font-variant:small-caps;\">Stavric, Milena</span>: Model Making. In: <span style=\"font-variant:small-caps;\">Hovestadt, L.</span> ; <span style=\"font-variant:small-caps;\">Hirschberg, U.</span> ; <span style=\"font-variant:small-caps;\">Fritz, O.</span> (Hrsg.): <i>Atlas of Digital Architecture</i>. Basel : Birkhäuser, 2020, S. 760","bjps":"<b>Sachs H and Stavric M</b> (2020) Model Making. In Hovestadt L, Hirschberg U and Fritz O (eds), <i>Atlas of Digital Architecture</i>. Basel: Birkhäuser, p. 760.","chicago":"Sachs, Hans, and Milena Stavric. “Model Making.” In <i>Atlas of Digital Architecture</i>, edited by Ludger Hovestadt, Urs  Hirschberg, and Oliver Fritz, 760. Basel: Birkhäuser, 2020. <a href=\"https://doi.org/10.1515/9783035620115-017\">https://doi.org/10.1515/9783035620115-017</a>.","ieee":"H. Sachs and M. Stavric, “Model Making,” in <i>Atlas of Digital Architecture</i>, L. Hovestadt, U. Hirschberg, and O. Fritz, Eds. Basel: Birkhäuser, 2020, p. 760. doi: <a href=\"https://doi.org/10.1515/9783035620115-017\">10.1515/9783035620115-017</a>.","van":"Sachs H, Stavric M. Model Making. In: Hovestadt L, Hirschberg U, Fritz O, editors. Atlas of Digital Architecture. Basel: Birkhäuser; 2020. p. 760.","ama":"Sachs H, Stavric M. Model Making. In: Hovestadt L, Hirschberg U, Fritz O, eds. <i>Atlas of Digital Architecture</i>. Birkhäuser; 2020:760. doi:<a href=\"https://doi.org/10.1515/9783035620115-017\">10.1515/9783035620115-017</a>","mla":"Sachs, Hans, and Milena Stavric. “Model Making.” <i>Atlas of Digital Architecture</i>, edited by Ludger Hovestadt et al., Birkhäuser, 2020, p. 760, <a href=\"https://doi.org/10.1515/9783035620115-017\">https://doi.org/10.1515/9783035620115-017</a>.","apa":"Sachs, H., &#38; Stavric, M. (2020). Model Making. In L. Hovestadt, U. Hirschberg, &#38; O. Fritz (Eds.), <i>Atlas of Digital Architecture</i> (p. 760). Birkhäuser. <a href=\"https://doi.org/10.1515/9783035620115-017\">https://doi.org/10.1515/9783035620115-017</a>","short":"H. Sachs, M. Stavric, in: L. Hovestadt, U. Hirschberg, O. Fritz (Eds.), Atlas of Digital Architecture, Birkhäuser, Basel, 2020, p. 760.","chicago-de":"Sachs, Hans und Milena Stavric. 2020. Model Making. In: <i>Atlas of Digital Architecture</i>, hg. von Ludger Hovestadt, Urs  Hirschberg, und Oliver Fritz, 760. Basel: Birkhäuser. doi:<a href=\"https://doi.org/10.1515/9783035620115-017\">10.1515/9783035620115-017</a>, .","ufg":"<b>Sachs, Hans/Stavric, Milena</b>: Model Making, in: <i>Hovestadt, Ludger/Hirschberg, Urs/Fritz, Oliver (Hgg.)</i>: Atlas of Digital Architecture, Basel 2020,  S. 760.","havard":"H. Sachs, M. Stavric, Model Making, in: L. Hovestadt, U. Hirschberg, O. 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Lemgo:  Technische Hochschule Ostwestfalen-Lippe; 2020.","ama":"Möllers M. <i>Relevante Faktoren Zur Simulation Der Schallausbreitung Für Eine Realitätsnahe Immersion in Virtuellen Räumen</i>. Lemgo:  Technische Hochschule Ostwestfalen-Lippe; 2020."},"language":[{"iso":"eng"}],"publisher":" Technische Hochschule Ostwestfalen-Lippe","date_created":"2020-08-26T08:47:22Z","author":[{"first_name":"Manik","last_name":"Möllers","id":"59363","full_name":"Möllers, Manik"}],"type":"bachelor_thesis","ddc":["700"]},{"has_accepted_license":"1","title":"Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis","file_date_updated":"2020-08-28T17:47:10Z","date_updated":"2023-03-15T13:49:46Z","language":[{"iso":"eng"}],"publisher":"Technische Hochschule Ostwestfalen-Lippe","date_created":"2020-08-28T17:46:35Z","citation":{"chicago-de":"Möller, Mario. 2020. <i>Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis</i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe.","ufg":"<b>Möller, Mario (2020)</b>: Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis, Lemgo.","apa":"Möller, M. (2020). <i>Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis</i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe.","mla":"Möller, Mario. <i>Schauspielführung - Ein Abgleich Gängiger Techniken Mit Erfahrungsberichten Aus Der Praxis</i>. Technische Hochschule Ostwestfalen-Lippe, 2020.","short":"M. Möller, Schauspielführung - Ein Abgleich Gängiger Techniken Mit Erfahrungsberichten Aus Der Praxis, Technische Hochschule Ostwestfalen-Lippe, Lemgo, 2020.","havard":"M. Möller, Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis, Technische Hochschule Ostwestfalen-Lippe, Lemgo, 2020.","chicago":"Möller, Mario. <i>Schauspielführung - Ein Abgleich Gängiger Techniken Mit Erfahrungsberichten Aus Der Praxis</i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe, 2020.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Möller, Mario</span>: <i>Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis</i>. Lemgo : Technische Hochschule Ostwestfalen-Lippe, 2020","bjps":"<b>Möller M</b> (2020) <i>Schauspielführung - Ein Abgleich Gängiger Techniken Mit Erfahrungsberichten Aus Der Praxis</i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe.","van":"Möller M. Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis. Lemgo: Technische Hochschule Ostwestfalen-Lippe; 2020.","ama":"Möller M. <i>Schauspielführung - Ein Abgleich Gängiger Techniken Mit Erfahrungsberichten Aus Der Praxis</i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe; 2020.","ieee":"M. Möller, <i>Schauspielführung - Ein Abgleich gängiger Techniken mit Erfahrungsberichten aus der Praxis</i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe, 2020."},"place":"Lemgo","ddc":["700"],"type":"bachelor_thesis","author":[{"first_name":"Mario","last_name":"Möller","id":"63713","full_name":"Möller, Mario"}],"supervisor":[{"first_name":"Kathrin","id":"29189","last_name":"Lemme","full_name":"Lemme, Kathrin"}],"_id":"3378","file":[{"file_name":"BA_MoellerMario_200821_digital.pdf","content_type":"application/pdf","relation":"main_file","date_updated":"2020-08-28T17:47:10Z","access_level":"local","creator":"yge-6z3","file_id":"3379","file_size":653547,"date_created":"2020-08-28T17:45:29Z"}],"status":"public","department":[{"_id":"DEP2001"}],"year":2020,"user_id":"68554"},{"department":[{"_id":"DEP2001"}],"user_id":"68554","year":2020,"status":"public","_id":"3385","file":[{"date_updated":"2020-08-31T08:18:03Z","access_level":"request","creator":"uy7-707","file_name":"O.Lofing_Praktische Arbeit_3D-Animation.mp4","content_type":"video/mp4","relation":"supplementary_material","file_id":"3386","file_size":152785434,"date_created":"2020-08-31T07:02:28Z"},{"date_created":"2020-08-31T07:06:08Z","file_id":"3387","file_size":6296335,"relation":"main_file","file_name":"O.Lofing_Dokumentation.pdf","content_type":"application/pdf","creator":"uy7-707","date_updated":"2020-08-31T08:18:03Z","access_level":"request"}],"supervisor":[{"first_name":"Marietta","last_name":"Ehret","id":"1201","full_name":"Ehret, Marietta"},{"id":"71782","last_name":"Schmohl","full_name":"Schmohl, Tobias","first_name":"Tobias"}],"ddc":["370"],"author":[{"first_name":"Olga","full_name":"Lofing, Olga","id":"68521","last_name":"Lofing"}],"type":"bachelor_thesis","date_created":"2020-08-31T06:55:46Z","publisher":"Technische Hochschule Ostwestfalen Lippe","language":[{"iso":"eng"}],"place":"Lemgo","citation":{"bjps":"<b>Lofing O</b> (2020) <i>Erklärvideos Und -Animationen - Die Methode Zur Wissensvermittlung</i>. Lemgo: Technische Hochschule Ostwestfalen Lippe.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Lofing, Olga</span>: <i>Erklärvideos und -animationen - Die Methode zur Wissensvermittlung</i>. Lemgo : Technische Hochschule Ostwestfalen Lippe, 2020","chicago":"Lofing, Olga. <i>Erklärvideos Und -Animationen - Die Methode Zur Wissensvermittlung</i>. Lemgo: Technische Hochschule Ostwestfalen Lippe, 2020.","ieee":"O. Lofing, <i>Erklärvideos und -animationen - Die Methode zur Wissensvermittlung</i>. Lemgo: Technische Hochschule Ostwestfalen Lippe, 2020.","van":"Lofing O. Erklärvideos und -animationen - Die Methode zur Wissensvermittlung. Lemgo: Technische Hochschule Ostwestfalen Lippe; 2020.","ama":"Lofing O. <i>Erklärvideos Und -Animationen - Die Methode Zur Wissensvermittlung</i>. Lemgo: Technische Hochschule Ostwestfalen Lippe; 2020.","short":"O. Lofing, Erklärvideos Und -Animationen - Die Methode Zur Wissensvermittlung, Technische Hochschule Ostwestfalen Lippe, Lemgo, 2020.","apa":"Lofing, O. (2020). <i>Erklärvideos und -animationen - Die Methode zur Wissensvermittlung</i>. Lemgo: Technische Hochschule Ostwestfalen Lippe.","mla":"Lofing, Olga. <i>Erklärvideos Und -Animationen - Die Methode Zur Wissensvermittlung</i>. Technische Hochschule Ostwestfalen Lippe, 2020.","ufg":"<b>Lofing, Olga (2020)</b>: Erklärvideos und -animationen - Die Methode zur Wissensvermittlung, Lemgo.","chicago-de":"Lofing, Olga. 2020. <i>Erklärvideos und -animationen - Die Methode zur Wissensvermittlung</i>. Lemgo: Technische Hochschule Ostwestfalen Lippe.","havard":"O. Lofing, Erklärvideos und -animationen - Die Methode zur Wissensvermittlung, Technische Hochschule Ostwestfalen Lippe, Lemgo, 2020."},"file_date_updated":"2020-08-31T08:18:03Z","has_accepted_license":"1","title":"Erklärvideos und -animationen - Die Methode zur Wissensvermittlung","date_updated":"2023-03-15T13:49:46Z"},{"status":"public","department":[{"_id":"DEP2001"}],"year":"2020","user_id":"45673","supervisor":[{"first_name":"Anke","full_name":"Stache, Anke","id":"76148","last_name":"Stache"},{"first_name":"Susann","full_name":"Ehrig, Susann","id":"69028","last_name":"Ehrig"}],"abstract":[{"lang":"ger","text":"Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand des nachhaltigen Bistros Old School."}],"file":[{"date_updated":"2020-09-07T06:22:17Z","access_level":"local","creator":"swd-yx8","file_name":"BA_Eickhoff_Design Manual Old School.pdf","content_type":"application/pdf","relation":"main_file","file_id":"3390","file_size":19091419,"date_created":"2020-08-31T10:30:05Z"},{"file_id":"3391","file_size":16163946,"date_created":"2020-08-31T10:30:03Z","date_updated":"2020-09-07T06:22:17Z","access_level":"local","creator":"swd-yx8","file_name":"BA_Eickhoff_Konzeption, Gestaltung und Umsetzung eines CD anhand eines nachhaltigen Bistros.pdf","content_type":"application/pdf","relation":"main_file"}],"publisher":"Technische Hochschule Ostwestfalen-Lippe","type":"bachelor_thesis","file_date_updated":"2020-09-07T06:22:17Z","date_updated":"2023-04-05T09:13:35Z","defense_date":"2020-08-25","_id":"3389","publication_status":"published","language":[{"iso":"ger"}],"date_created":"2020-08-31T10:31:36Z","citation":{"ama":"Eickhoff F. <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Technische Hochschule Ostwestfalen-Lippe; 2020.","van":"Eickhoff F. Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros. Lemgo: Technische Hochschule Ostwestfalen-Lippe; 2020.","ieee":"F. Eickhoff, <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Lemgo: Technische Hochschule Ostwestfalen-Lippe, 2020.","chicago":"Eickhoff, Fabienne. <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Lemgo: Technische Hochschule Ostwestfalen-Lippe, 2020.","bjps":"<b>Eickhoff F</b> (2020) <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Lemgo: Technische Hochschule Ostwestfalen-Lippe.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Eickhoff, Fabienne</span>: <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Lemgo : Technische Hochschule Ostwestfalen-Lippe, 2020","havard":"F. Eickhoff, Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros., Technische Hochschule Ostwestfalen-Lippe, Lemgo, 2020.","ufg":"<b>Eickhoff, Fabienne</b>: Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros., Lemgo 2020.","chicago-de":"Eickhoff, Fabienne. 2020. <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Lemgo: Technische Hochschule Ostwestfalen-Lippe.","short":"F. Eickhoff, Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros., Technische Hochschule Ostwestfalen-Lippe, Lemgo, 2020.","apa":"Eickhoff, F. (2020). <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Technische Hochschule Ostwestfalen-Lippe.","mla":"Eickhoff, Fabienne. <i>Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros.</i> Technische Hochschule Ostwestfalen-Lippe, 2020."},"place":"Lemgo","ddc":["760"],"author":[{"id":"67649","last_name":"Eickhoff","full_name":"Eickhoff, Fabienne","first_name":"Fabienne"}],"has_accepted_license":"1","title":"Konzeption, Gestaltung und Umsetzung eines Corporate Designs anhand eines nachhaltigen Bistros."},{"date_updated":"2023-03-15T13:49:46Z","title":"Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument ","has_accepted_license":"1","file_date_updated":"2021-01-19T13:23:03Z","citation":{"din1505-2-1":"<span style=\"font-variant:small-caps;\">Möller, Alexandra</span>: <i>Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument </i>. Lemgo : Technische Hochschule Ostwestfalen-Lippe, 2020","bjps":"<b>Möller A</b> (2020) <i>Der Internetauftritt von Kleinen Und Mittelständischen Unternehmen Als Marketinginstrument </i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe.","chicago":"Möller, Alexandra. <i>Der Internetauftritt von Kleinen Und Mittelständischen Unternehmen Als Marketinginstrument </i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe, 2020.","ieee":"A. Möller, <i>Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument </i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe, 2020.","van":"Möller A. Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument . Lemgo: Technische Hochschule Ostwestfalen-Lippe; 2020.","ama":"Möller A. <i>Der Internetauftritt von Kleinen Und Mittelständischen Unternehmen Als Marketinginstrument </i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe; 2020.","apa":"Möller, A. (2020). <i>Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument </i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe.","mla":"Möller, Alexandra. <i>Der Internetauftritt von Kleinen Und Mittelständischen Unternehmen Als Marketinginstrument </i>. Technische Hochschule Ostwestfalen-Lippe, 2020.","short":"A. Möller, Der Internetauftritt von Kleinen Und Mittelständischen Unternehmen Als Marketinginstrument , Technische Hochschule Ostwestfalen-Lippe, Lemgo, 2020.","chicago-de":"Möller, Alexandra. 2020. <i>Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument </i>. Lemgo: Technische Hochschule Ostwestfalen-Lippe.","ufg":"<b>Möller, Alexandra (2020)</b>: Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument , Lemgo.","havard":"A. Möller, Der Internetauftritt von kleinen und mittelständischen Unternehmen als Marketinginstrument , Technische Hochschule Ostwestfalen-Lippe, Lemgo, 2020."},"place":"Lemgo","language":[{"iso":"eng"}],"date_created":"2020-09-01T07:25:02Z","publisher":"Technische Hochschule Ostwestfalen-Lippe","author":[{"full_name":"Möller, Alexandra","id":"67171","last_name":"Möller","first_name":"Alexandra"}],"type":"master_thesis","ddc":["070"],"supervisor":[{"first_name":"Frank","full_name":"Lechtenberg, Frank","id":"10784","last_name":"Lechtenberg"}],"oa":"1","_id":"3392","file":[{"relation":"main_file","content_type":"application/pdf","file_name":"Bachelorarbeit_AlexandraMoeller.pdf","title":"Masterarbeit_AlexandraMoeller","creator":"zw3-usr","date_updated":"2021-01-19T13:23:03Z","access_level":"open_access","date_created":"2020-09-01T07:23:46Z","file_id":"3393","file_size":3137760}],"status":"public","year":2020,"user_id":"68554","department":[{"_id":"DEP2001"}]},{"series_title":"Industrial engineering and ergonomics","_id":"12717","author":[{"first_name":"Benedikt","full_name":"Latos, Benedikt","id":"84474","last_name":"Latos"}],"intvolume":"        37","publication_identifier":{"isbn":["978-3-8440-7744-5"]},"place":"Düren","citation":{"short":"B. Latos, Auswirkungen von Komplexität auf die Performance von Produktionsgruppen, Shaker Verlag, Düren, 2020.","apa":"Latos, B. (2020). <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i> (Vol. 37). Shaker Verlag. <a href=\"https://doi.org/10.2370/9783844077445\">https://doi.org/10.2370/9783844077445</a>","mla":"Latos, Benedikt. <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i>. Shaker Verlag, 2020, <a href=\"https://doi.org/10.2370/9783844077445\">https://doi.org/10.2370/9783844077445</a>.","ufg":"<b>Latos, Benedikt</b>: Auswirkungen von Komplexität auf die Performance von Produktionsgruppen, Bd. 37, Düren 2020 (Industrial engineering and ergonomics).","chicago-de":"Latos, Benedikt. 2020. <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i>. Bd. 37. Industrial engineering and ergonomics. Düren: Shaker Verlag. doi:<a href=\"https://doi.org/10.2370/9783844077445\">10.2370/9783844077445</a>, .","havard":"B. Latos, Auswirkungen von Komplexität auf die Performance von Produktionsgruppen, Shaker Verlag, Düren, 2020.","bjps":"<b>Latos B</b> (2020) <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i>. Düren: Shaker Verlag.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Latos, Benedikt</span>: <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i>, <i>Industrial engineering and ergonomics</i>. Bd. 37. Düren : Shaker Verlag, 2020","chicago":"Latos, Benedikt. <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i>. Vol. 37. Industrial engineering and ergonomics. Düren: Shaker Verlag, 2020. <a href=\"https://doi.org/10.2370/9783844077445\">https://doi.org/10.2370/9783844077445</a>.","ieee":"B. Latos, <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i>, vol. 37. Düren: Shaker Verlag, 2020. doi: <a href=\"https://doi.org/10.2370/9783844077445\">10.2370/9783844077445</a>.","van":"Latos B. Auswirkungen von Komplexität auf die Performance von Produktionsgruppen. Düren: Shaker Verlag; 2020. 324 p. (Industrial engineering and ergonomics; vol. 37).","ama":"Latos B. <i>Auswirkungen von Komplexität auf die Performance von Produktionsgruppen</i>. Vol 37. Shaker Verlag; 2020. doi:<a href=\"https://doi.org/10.2370/9783844077445\">10.2370/9783844077445</a>"},"language":[{"iso":"ger"}],"date_created":"2025-03-19T15:33:58Z","publication_status":"published","volume":37,"alternative_title":["Effects of complexity on the performance of production groups "],"main_file_link":[{"url":"https://www.shaker.de/Online-Gesamtkatalog-Download/2025.03.19-16.26.58-193.16.112.100-rad4B15C.tmp/978-3-8440-7744-5_INH.PDF"}],"title":"Auswirkungen von Komplexität auf die Performance von Produktionsgruppen","user_id":"83781","year":"2020","department":[{"_id":"DEP1500"}],"status":"public","keyword":["Produktionssystem","Komplexes System","Teamwork","Leistungsmessung"],"abstract":[{"text":"Der Anstieg der Komplexität in Produktionssystemen stellt eine der größten Herausforderungen für produzierende\r\nUnternehmen dar. In der vorliegenden Dissertation werden mögliche Auswirkungen von Komplexität auf die Performance von Produktionsgruppen untersucht. Es werden sechs Studien durchgeführt, die inhaltlich und methodisch aufeinander aufbauen und somit einen vollständigen Forschungsprozess von der initialen Begriffsbestimmung bis hin zur Ableitung von Gestaltungsempfehlungen für die betriebliche Praxis beschreiben.\r\nIn der Explorationsphase wird zunächst eine qualitative Interviewstudie durchgeführt, um konkrete Treiber für das Phänomen der Komplexität in digitalisierten Arbeitssystemen zu identifizieren. Basierend auf zwei systematischen Literaturstudien wird der Stand der Forschung zu (1) Komplexitätsmodellen und (2) Gruppenperformancemodellen im Kontext von Produktionssystemen strukturiert erarbeitet und das bestehende Forschungsdefizit offengelegt.\r\nAuf der Grundlage der Vorstudien wird ein hypothetisches Modell zur Erklärung der Performance von Produktionsgruppen entwickelt, das neben bekannten Einflussgrößen aus der Teamforschung verschiedene Komplexitätsdimensionen berücksichtigt. Die Operationalisierung der latenten Variablen erfolgt mit Hilfe einer weiteren qualitativen Interviewstudie. Das\r\nGruppenperformancemodell wird in einer Fragebogenstudie (n = 455) unter Anwendung der Methode der Strukturgleichungsmodellierung empirisch evaluiert. In der statistischen Auswertung wird u. a. festgestellt, dass ein positiver Zusammenhang zwischen der Aufgabenkomplexität und der Gruppenperformance besteht, der über die Qualität der Zusammenarbeit vermittelt wird. Dahingegen wird ein negativer Zusammenhang zwischen der Komplexität des Gruppendesigns und der Gruppenperformance identifiziert, der ebenfalls über die Qualität der Zusammenarbeit vermittelt wird. Aus den Ergebnissen werden konkrete Empfehlungen für die komplexitätsbezogene Gestaltung von Gruppenarbeit in der Produktion abgeleitet.\r\nDarüber hinaus wird eine Metrik zur Erfassung der Komplexität des Arbeitsprozesses von Produktionsgruppen entwickelt und in einer Simulationsstudie evaluiert. Die Metrik kann bereits in Planungsphasen von Produktionssystemen verwendet werden, um alternative arbeitsorganisatorische Gestaltungsoptionen anhand des resultierenden Komplexitätsniveaus für die Produktionsgruppe vergleichend zu analysieren. Zudem können die Auswirkungen unterschiedlicher Qualifikationsprofile auf das Komplexitätsniveau und die Performance einer Produktionsgruppe untersucht werden.","lang":"ger"},{"text":"The increase in complexity in production systems represents one of the major challenges for manufacturing companies. In this dissertation, possible effects of complexity on the performance of production groups are examined. Six studies are carried out, which build on each other in terms of content and methodology and thus cover a complete research process from\r\nthe initial definition of key concepts up to the derivation of design recommendations for operational practice.\r\nWithin the exploratory phase, a qualitative interview study is conducted in order to identify drivers of the phenomenon of complexity in digitalized work systems. Based on two systematic literature studies, the state of research on (1) complexity models and (2) group performance models in the context of production systems is examined in a structured way and the existing research deficit is pointed out.\r\nOn the basis of the preliminary studies, a hypothetical model is developed to explain the performance of production groups. The model includes different complexity dimensions in addition to known influencing variables from team research. The operationalization of the latent variables is carried out with a further qualitative interview study. The group performance model is\r\nempirically evaluated in a questionnaire study (n = 455) using the method of structural equation modelling. On the one hand, the results of the statistical analysis show that there is a positive relationship between task complexity and group performance, which is mediated by the quality of teamwork. On the other hand, a negative relationship is identified between the complexity of group design and group performance, which is also mediated by the quality of teamwork. The findings are used to derive specific recommendations for the complexity-related design of group work in production.\r\nIn addition, a metric to capture the complexity of the work process of production groups is developed and evaluated in a simulation study. The metric is applicable in early planning phases of production systems. The resulting complexity level for the production group can be used for a comparative analysis of organizational design options. Furthermore, the effects of\r\ndifferent group qualification profiles on the complexity level or performance of a production group can be assessed.","lang":"eng"}],"supervisor":[{"last_name":"Mütze-Niewöhner","full_name":"Mütze-Niewöhner, Susanne","first_name":"Susanne"},{"full_name":"Nitsch, Verena","last_name":"Nitsch","first_name":"Verena"}],"page":"324","type":"dissertation","publisher":"Shaker Verlag","defense_date":"2020-10-26","doi":"10.2370/9783844077445","date_updated":"2025-03-21T08:30:45Z"},{"title":"Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide","publication_identifier":{"eissn":["1944-9097"],"issn":["0362-028X"]},"isi":"1","author":[{"first_name":"Barbara","full_name":"Becker, Barbara","id":"12640","last_name":"Becker"},{"last_name":"Dabisch-Ruthe","id":"66516","full_name":"Dabisch-Ruthe, Mareike","first_name":"Mareike","orcid":"https://orcid.org/0009-0008-7644-0826"},{"full_name":"Pfannebecker, Jens","last_name":"Pfannebecker","id":"45690","first_name":"Jens","orcid":"0009-0005-4133-5442"}],"intvolume":"        83","date_created":"2025-04-15T07:59:20Z","language":[{"iso":"eng"}],"pmid":"1","publication_status":"published","volume":83,"place":"Des Moines, Iowa","citation":{"ieee":"B. Becker, M. Dabisch-Ruthe, and J. Pfannebecker, “Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide,” <i>  Journal of food protection </i>, vol. 83, no. 1, pp. 45–51, 2020, doi: <a href=\"https://doi.org/10.4315/0362-028X.JFP-19-238\">10.4315/0362-028X.JFP-19-238</a>.","van":"Becker B, Dabisch-Ruthe M, Pfannebecker J. Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide.   Journal of food protection . 2020;83(1):45–51.","ama":"Becker B, Dabisch-Ruthe M, Pfannebecker J. Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide. <i>  Journal of food protection </i>. 2020;83(1):45-51. doi:<a href=\"https://doi.org/10.4315/0362-028X.JFP-19-238\">10.4315/0362-028X.JFP-19-238</a>","din1505-2-1":"<span style=\"font-variant:small-caps;\">Becker, Barbara</span> ; <span style=\"font-variant:small-caps;\">Dabisch-Ruthe, Mareike</span> ; <span style=\"font-variant:small-caps;\">Pfannebecker, Jens</span>: Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide. In: <i>  Journal of food protection </i> Bd. 83. Des Moines, Iowa, IAFP (2020), Nr. 1, S. 45–51","bjps":"<b>Becker B, Dabisch-Ruthe M and Pfannebecker J</b> (2020) Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide. <i>  Journal of food protection </i> <b>83</b>, 45–51.","chicago":"Becker, Barbara, Mareike Dabisch-Ruthe, and Jens Pfannebecker. “Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide.” <i>  Journal of Food Protection </i> 83, no. 1 (2020): 45–51. <a href=\"https://doi.org/10.4315/0362-028X.JFP-19-238\">https://doi.org/10.4315/0362-028X.JFP-19-238</a>.","havard":"B. Becker, M. Dabisch-Ruthe, J. Pfannebecker, Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide,   Journal of Food Protection . 83 (2020) 45–51.","apa":"Becker, B., Dabisch-Ruthe, M., &#38; Pfannebecker, J. (2020). Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide. <i>  Journal of Food Protection </i>, <i>83</i>(1), 45–51. <a href=\"https://doi.org/10.4315/0362-028X.JFP-19-238\">https://doi.org/10.4315/0362-028X.JFP-19-238</a>","mla":"Becker, Barbara, et al. “Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide.” <i>  Journal of Food Protection </i>, vol. 83, no. 1, 2020, pp. 45–51, <a href=\"https://doi.org/10.4315/0362-028X.JFP-19-238\">https://doi.org/10.4315/0362-028X.JFP-19-238</a>.","short":"B. Becker, M. Dabisch-Ruthe, J. Pfannebecker,   Journal of Food Protection  83 (2020) 45–51.","chicago-de":"Becker, Barbara, Mareike Dabisch-Ruthe und Jens Pfannebecker. 2020. Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide. <i>  Journal of food protection </i> 83, Nr. 1: 45–51. doi:<a href=\"https://doi.org/10.4315/0362-028X.JFP-19-238\">10.4315/0362-028X.JFP-19-238</a>, .","ufg":"<b>Becker, Barbara/Dabisch-Ruthe, Mareike/Pfannebecker, Jens</b>: Inactivation of Murine Norovirus on Fruit and Vegetable Surfaces by Vapor Phase Hydrogen Peroxide, in: <i>  Journal of food protection </i> 83 (2020), H. 1,  S. 45–51."},"_id":"12787","publication":"  Journal of food protection ","issue":"1","quality_controlled":"1","external_id":{"pmid":["31821018"],"isi":["000539418200006"]},"doi":"10.4315/0362-028X.JFP-19-238","date_updated":"2025-06-26T13:42:15Z","type":"scientific_journal_article","publisher":"IAFP","keyword":["Fruits","Inactivation","Murine norovirus","Vapor phase hydrogen peroxide","Vegetables"],"page":"45-51","abstract":[{"lang":"eng","text":"Vapor phase hydrogen peroxide (H2O2) can be utilized to inactivate murine norovirus (MNV), a surrogate of human norovirus, on surface areas. However, vapor phase H2O2 inactivation of virus on fruits and vegetables has not been characterized. In this study, MNV was used to determine whether vaporized H2O2 inactivates virus on surfaces of various fruits and vegetables (apples, blueberries, cucumbers, and strawberries). The effect of vapor phase H2O2 decontamination was investigated with two application systems. Plaque assays were performed after virus recovery from untreated and treated fresh produce to compare the quantity of infective MNV. The Mann-Whitney U test was applied to the test results to evaluate the virus titer reductions of treated food samples, with significance set at P <= 0.05. The infective MNV populations were significantly reduced on smooth surfaces by 4.3 log PFU (apples, P < 0.00001) and 4 log PFU or below the detection limit (blueberries, P = 0.0074) by treatment with vapor phase H2O2 (60 min, maximum of 214 ppm of H2O2). Similar treatments of artificially contaminated cucumbers resulted in a virus titer reduction of 1.9 log PFU. Treatment of inoculated strawberries resulted in 0.1and 2.8-log reductions of MNV. However, MNV reduction rates on cucumbers (P = 0.3809) and strawberries (P = 0,7414) were not significant. Triangle tests and color measurements of untreated and treated apples, cucumbers, blueberries, and strawberries revealed no differences in color and consistency after H2O2 treatment. No increase of the H2O2 concentration in treated fruits and vegetables compared with untreated produce was observed. This study reveals for the first time the conditions under which vapor phase H2O2 inactivates MNV on selected fresh fruit and vegetable surfaces."}],"department":[{"_id":"DEP4000"}],"year":"2020","user_id":"83781","status":"public"},{"series_title":"Procedia Manufacturing","publication":"System-Integrated Intelligence - Intelligent, Flexible and Connected Systems in Products and Production : Proceedings of the 5th International Conference on System-Integrated Intelligence (SysInt 2020), Bremen, Germany (","_id":"12794","intvolume":"        52","author":[{"orcid":"0000-0002-6529-6215","full_name":"Deuter, Andreas","id":"62088","last_name":"Deuter","first_name":"Andreas"},{"id":"74291","last_name":"Imort","full_name":"Imort, Sebastian","first_name":"Sebastian"}],"publication_identifier":{"issn":["2351-9789"]},"citation":{"havard":"A. Deuter, S. Imort, PLM/ALM Integration With The Asset Administration Shell, Elsevier BV, 2020.","short":"A. Deuter, S. Imort, PLM/ALM Integration With The Asset Administration Shell, Elsevier BV, 2020.","apa":"Deuter, A., &#38; Imort, S. (2020). PLM/ALM Integration With The Asset Administration Shell. In K.-D. Thoben, B. Dekena, W.  Lang, &#38; A.  Trächtler (Eds.), <i>System-Integrated Intelligence - Intelligent, Flexible and Connected Systems in Products and Production : Proceedings of the 5th International Conference on System-Integrated Intelligence (SysInt 2020), Bremen, Germany (</i> (Vol. 52, pp. 234–240). Elsevier BV. <a href=\"https://doi.org/10.1016/j.promfg.2020.11.040\">https://doi.org/10.1016/j.promfg.2020.11.040</a>","mla":"Deuter, Andreas, and Sebastian Imort. “PLM/ALM Integration With The Asset Administration Shell.” <i>System-Integrated Intelligence - Intelligent, Flexible and Connected Systems in Products and Production : Proceedings of the 5th International Conference on System-Integrated Intelligence (SysInt 2020), Bremen, Germany (</i>, edited by Klaus-Dieter  Thoben et al., vol. 52, Elsevier BV, 2020, pp. 234–40, <a href=\"https://doi.org/10.1016/j.promfg.2020.11.040\">https://doi.org/10.1016/j.promfg.2020.11.040</a>.","ufg":"<b>Deuter, Andreas/Imort, Sebastian</b>: PLM/ALM Integration With The Asset Administration Shell, Bd. 52, hg. von Thoben, Klaus-Dieter u. a., o. O. 2020 (Procedia Manufacturing).","chicago-de":"Deuter, Andreas und Sebastian Imort. 2020. <i>PLM/ALM Integration With The Asset Administration Shell</i>. Hg. von Klaus-Dieter  Thoben, Berend  Dekena, Walter   Lang, und Ansgar  Trächtler. <i>System-Integrated Intelligence - Intelligent, Flexible and Connected Systems in Products and Production : Proceedings of the 5th International Conference on System-Integrated Intelligence (SysInt 2020), Bremen, Germany (</i>. Bd. 52. Procedia Manufacturing. Elsevier BV. doi:<a href=\"https://doi.org/10.1016/j.promfg.2020.11.040\">10.1016/j.promfg.2020.11.040</a>, .","ieee":"A. Deuter and S. Imort, <i>PLM/ALM Integration With The Asset Administration Shell</i>, vol. 52. Elsevier BV, 2020, pp. 234–240. doi: <a href=\"https://doi.org/10.1016/j.promfg.2020.11.040\">10.1016/j.promfg.2020.11.040</a>.","van":"Deuter A, Imort S. PLM/ALM Integration With The Asset Administration Shell. Thoben KD, Dekena B,  Lang W,  Trächtler A, editors. System-Integrated Intelligence - Intelligent, Flexible and Connected Systems in Products and Production : Proceedings of the 5th International Conference on System-Integrated Intelligence (SysInt 2020), Bremen, Germany (. Elsevier BV; 2020. (Procedia Manufacturing; vol. 52).","ama":"Deuter A, Imort S. <i>PLM/ALM Integration With The Asset Administration Shell</i>. Vol 52. (Thoben KD, Dekena B,  Lang W,  Trächtler A, eds.). Elsevier BV; 2020:234-240. doi:<a href=\"https://doi.org/10.1016/j.promfg.2020.11.040\">10.1016/j.promfg.2020.11.040</a>","bjps":"<b>Deuter A and Imort S</b> (2020) <i>PLM/ALM Integration With The Asset Administration Shell</i>, Thoben K-D et al. (eds). Elsevier BV.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Deuter, Andreas</span> ; <span style=\"font-variant:small-caps;\">Imort, Sebastian</span> ; <span style=\"font-variant:small-caps;\">Thoben, K.-D.</span> ; <span style=\"font-variant:small-caps;\">Dekena, B.</span> ; <span style=\"font-variant:small-caps;\"> Lang, W.</span> ; <span style=\"font-variant:small-caps;\"> Trächtler, A.</span> (Hrsg.): <i>PLM/ALM Integration With The Asset Administration Shell</i>, <i>Procedia Manufacturing</i>. Bd. 52 : Elsevier BV, 2020","chicago":"Deuter, Andreas, and Sebastian Imort. <i>PLM/ALM Integration With The Asset Administration Shell</i>. Edited by Klaus-Dieter  Thoben, Berend  Dekena, Walter   Lang, and Ansgar  Trächtler. <i>System-Integrated Intelligence - Intelligent, Flexible and Connected Systems in Products and Production : Proceedings of the 5th International Conference on System-Integrated Intelligence (SysInt 2020), Bremen, Germany (</i>. Vol. 52. Procedia Manufacturing. Elsevier BV, 2020. <a href=\"https://doi.org/10.1016/j.promfg.2020.11.040\">https://doi.org/10.1016/j.promfg.2020.11.040</a>."},"date_created":"2025-04-15T10:20:05Z","language":[{"iso":"eng"}],"publication_status":"published","volume":52,"title":"PLM/ALM Integration With The Asset Administration Shell","year":"2020","user_id":"83781","department":[{"_id":"DEP7022"},{"_id":"DEP1306"}],"status":"public","keyword":["PLM","ALM","ReqIF","PLM XML","OSLC","Asset Administration Shell"],"abstract":[{"lang":"eng","text":"Modern product development utilizes both Product Lifecycle Management (PLM) and Application Lifecycle Management (ALM). PLM addresses the hardware lifecycle of a product, whereas ALM addresses the software lifecycle. In recent years, industry and academia have developed several PLM/ALM integration concepts to realize efficient management of the product lifecycle across all domains. However, the solutions available in practice are typically vendor-driven. Therefore, they are not generally applicable even if standards such as OSLC (Open Services for Lifecycle Cooperation) are applied.\r\n\r\nThe consortium \"Plattform Industrie 4.0\" has recently introduced a standardized digital representation of an asset (e.g., a smart product): the Asset Administration Shell (AAS). The AAS has the potential to integrate PLM/ALM data sets in a single product model and hence to provide a generally applicable interface for PLM/ALM integration. However, until now there has not been a concept to prove this potential. The aim of this work is to develop such new strategies (named Plm4AAS) using AAS submodels. This article explains the semi-automatic generation of PLM/ALM submodels and how to link elements between these submodels. The AASX Package Explorer, an AAS management software tool, is used to demonstrate the results. The article finishes with a discussion about the potential of the AAS as a standardized concept for PLM/ALM integration. (C) 2020 The Authors. Published by Elsevier B.V. Peer-review under responsibility of the scientific committee of the 5th International Conference on System-Integrated Intelligence."}],"page":"234-240","conference":{"name":"5th International Conference on System-Integrated Intelligence (SysInt)","start_date":"2020-11-11","end_date":"2020-11-13","location":"Online"},"type":"conference_editor_article","publisher":"Elsevier BV","editor":[{"last_name":"Thoben","full_name":"Thoben, Klaus-Dieter ","first_name":"Klaus-Dieter "},{"first_name":"Berend ","full_name":"Dekena, Berend ","last_name":"Dekena"},{"full_name":" Lang, Walter ","last_name":" Lang","first_name":"Walter "},{"last_name":" Trächtler","full_name":" Trächtler, Ansgar","first_name":"Ansgar"}],"doi":"10.1016/j.promfg.2020.11.040","date_updated":"2025-06-26T13:40:25Z"},{"editor":[{"first_name":"Peggy","full_name":"Cellier, Peggy","last_name":"Cellier"},{"full_name":"Driessens, Kurt","last_name":"Driessens","first_name":"Kurt"}],"publisher":"Springer International Publishing","type":"conference_editor_article","date_updated":"2025-06-26T13:36:14Z","doi":"10.1007/978-3-030-43887-6_39","status":"public","department":[{"_id":"DEP2000"}],"year":"2020","user_id":"83781","page":"462–469","conference":{"location":"Würzburg","end_date":"2019-09-20","start_date":"2019-09-16","name":"European Conference on Machine Learning and Principles and Practice of Knowledge Discovery in Databases (ECML PKDD)"},"abstract":[{"text":"Writing chorales in the style of Bach has been a music theory exercise for generations of music students. As such it is not surprising that automatic Bach chorale harmonization has been a topic in music technology for decades. We suggest several improvements to current neural network solutions based on musicological insights into human choral composition practices. Evaluations with expert listeners show that the generated chorales closely resemble Bach's harmonization style.","lang":"eng"}],"keyword":["Bach chorale harmonization","Deep learning","Beam search"],"volume":1168,"publication_status":"published","language":[{"iso":"eng"}],"date_created":"2025-04-16T07:52:39Z","citation":{"bjps":"<b>Leemhuis A, Waloschek S and Hadjakos A</b> (2020) <i>Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization</i>, Cellier P and Driessens K (eds). Cham: Springer International Publishing.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Leemhuis, Alexander</span> ; <span style=\"font-variant:small-caps;\">Waloschek, Simon</span> ; <span style=\"font-variant:small-caps;\">Hadjakos, Aristotelis</span> ; <span style=\"font-variant:small-caps;\">Cellier, P.</span> ; <span style=\"font-variant:small-caps;\">Driessens, K.</span> (Hrsg.): <i>Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization</i>, <i>Communications in Computer and Information Science </i>. Bd. 1168. Cham : Springer International Publishing, 2020","chicago":"Leemhuis, Alexander, Simon Waloschek, and Aristotelis Hadjakos. <i>Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization</i>. Edited by Peggy Cellier and Kurt Driessens. <i>Machine Learning and Knowledge Discovery in Databases : International Workshops of ECML PKDD 2019</i>. Vol. 1168. Communications in Computer and Information Science . Cham: Springer International Publishing, 2020. <a href=\"https://doi.org/10.1007/978-3-030-43887-6_39\">https://doi.org/10.1007/978-3-030-43887-6_39</a>.","ieee":"A. Leemhuis, S. Waloschek, and A. Hadjakos, <i>Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization</i>, vol. 1168. Cham: Springer International Publishing, 2020, pp. 462–469. doi: <a href=\"https://doi.org/10.1007/978-3-030-43887-6_39\">10.1007/978-3-030-43887-6_39</a>.","ama":"Leemhuis A, Waloschek S, Hadjakos A. <i>Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization</i>. Vol 1168. (Cellier P, Driessens K, eds.). Springer International Publishing; 2020:462-469. doi:<a href=\"https://doi.org/10.1007/978-3-030-43887-6_39\">10.1007/978-3-030-43887-6_39</a>","van":"Leemhuis A, Waloschek S, Hadjakos A. Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization. Cellier P, Driessens K, editors. Machine Learning and Knowledge Discovery in Databases : International Workshops of ECML PKDD 2019. Cham: Springer International Publishing; 2020. (Communications in Computer and Information Science ; vol. 1168).","short":"A. Leemhuis, S. Waloschek, A. Hadjakos, Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization, Springer International Publishing, Cham, 2020.","mla":"Leemhuis, Alexander, et al. “Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization.” <i>Machine Learning and Knowledge Discovery in Databases : International Workshops of ECML PKDD 2019</i>, edited by Peggy Cellier and Kurt Driessens, vol. 1168, Springer International Publishing, 2020, pp. 462–69, <a href=\"https://doi.org/10.1007/978-3-030-43887-6_39\">https://doi.org/10.1007/978-3-030-43887-6_39</a>.","apa":"Leemhuis, A., Waloschek, S., &#38; Hadjakos, A. (2020). Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization. In P. Cellier &#38; K. Driessens (Eds.), <i>Machine Learning and Knowledge Discovery in Databases : International Workshops of ECML PKDD 2019</i> (Vol. 1168, pp. 462–469). Springer International Publishing. <a href=\"https://doi.org/10.1007/978-3-030-43887-6_39\">https://doi.org/10.1007/978-3-030-43887-6_39</a>","ufg":"<b>Leemhuis, Alexander/Waloschek, Simon/Hadjakos, Aristotelis</b>: Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization, Bd. 1168, hg. von Cellier, Peggy/Driessens, Kurt, Cham 2020 (Communications in Computer and Information Science ).","chicago-de":"Leemhuis, Alexander, Simon Waloschek und Aristotelis Hadjakos. 2020. <i>Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization</i>. Hg. von Peggy Cellier und Kurt Driessens. <i>Machine Learning and Knowledge Discovery in Databases : International Workshops of ECML PKDD 2019</i>. Bd. 1168. Communications in Computer and Information Science . Cham: Springer International Publishing. doi:<a href=\"https://doi.org/10.1007/978-3-030-43887-6_39\">10.1007/978-3-030-43887-6_39</a>, .","havard":"A. Leemhuis, S. Waloschek, A. Hadjakos, Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization, Springer International Publishing, Cham, 2020."},"place":"Cham","publication_identifier":{"issn":["1865-0929"],"eissn":["1865-0937"],"isbn":["978-3-030-43886-9"],"eisbn":["978-3-030-43887-6"]},"intvolume":"      1168","author":[{"first_name":"Alexander","full_name":"Leemhuis, Alexander","last_name":"Leemhuis"},{"first_name":"Simon","last_name":"Waloschek","full_name":"Waloschek, Simon"},{"full_name":"Hadjakos, Aristotelis","last_name":"Hadjakos","id":"58704","first_name":"Aristotelis"}],"title":"Bacher than Bach? On Musicologically Informed AI-Based Bach Chorale Harmonization","publication":"Machine Learning and Knowledge Discovery in Databases : International Workshops of ECML PKDD 2019","series_title":"Communications in Computer and Information Science ","_id":"12807"},{"_id":"12812","publication":" Proceedings of the International Conference on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1","title":"Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0","citation":{"van":"Berns F, Lange-Hegermann M, Beecks C. Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0. Panetto H, Madani K, Smirnov A, editors.  Proceedings of the International Conference on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1. SCITEPRESS - Science and Technology Publications; 2020.","ama":"Berns F, Lange-Hegermann M, Beecks C. <i>Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0</i>. (Panetto H, Madani K, Smirnov A, eds.). SCITEPRESS - Science and Technology Publications; 2020:87-92. doi:<a href=\"https://doi.org/10.5220/0010130300870092\">10.5220/0010130300870092</a>","ieee":"F. Berns, M. Lange-Hegermann, and C. Beecks, <i>Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0</i>. SCITEPRESS - Science and Technology Publications, 2020, pp. 87–92. doi: <a href=\"https://doi.org/10.5220/0010130300870092\">10.5220/0010130300870092</a>.","havard":"F. Berns, M. Lange-Hegermann, C. Beecks, Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0, SCITEPRESS - Science and Technology Publications, 2020.","ufg":"<b>Berns, Fabian/Lange-Hegermann, Markus/Beecks, Christian</b>: Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0, hg. von Panetto, H./Madani, K./Smirnov, A., o. O. 2020.","chicago":"Berns, Fabian, Markus Lange-Hegermann, and Christian Beecks. <i>Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0</i>. Edited by H. Panetto, K. Madani, and A. Smirnov. <i> Proceedings of the International Conference on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1</i>. SCITEPRESS - Science and Technology Publications, 2020. <a href=\"https://doi.org/10.5220/0010130300870092\">https://doi.org/10.5220/0010130300870092</a>.","chicago-de":"Berns, Fabian, Markus Lange-Hegermann und Christian Beecks. 2020. <i>Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0</i>. Hg. von H. Panetto, K. Madani, und A. Smirnov. <i> Proceedings of the International Conference on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1</i>. SCITEPRESS - Science and Technology Publications. doi:<a href=\"https://doi.org/10.5220/0010130300870092\">10.5220/0010130300870092</a>, .","short":"F. Berns, M. Lange-Hegermann, C. Beecks, Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0, SCITEPRESS - Science and Technology Publications, 2020.","bjps":"<b>Berns F, Lange-Hegermann M and Beecks C</b> (2020) <i>Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0</i>, Panetto H, Madani K and Smirnov A (eds). SCITEPRESS - Science and Technology Publications.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Berns, Fabian</span> ; <span style=\"font-variant:small-caps;\">Lange-Hegermann, Markus</span> ; <span style=\"font-variant:small-caps;\">Beecks, Christian</span> ; <span style=\"font-variant:small-caps;\">Panetto, H.</span> ; <span style=\"font-variant:small-caps;\">Madani, K.</span> ; <span style=\"font-variant:small-caps;\">Smirnov, A.</span> (Hrsg.): <i>Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0</i> : SCITEPRESS - Science and Technology Publications, 2020","apa":"Berns, F., Lange-Hegermann, M., &#38; Beecks, C. (2020). Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0. In H. Panetto, K. Madani, &#38; A. Smirnov (Eds.), <i> Proceedings of the International Conference on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1</i> (pp. 87–92). SCITEPRESS - Science and Technology Publications. <a href=\"https://doi.org/10.5220/0010130300870092\">https://doi.org/10.5220/0010130300870092</a>","mla":"Berns, Fabian, et al. “Towards Gaussian Processes for Automatic and Interpretable Anomaly Detection in Industry 4.0.” <i> Proceedings of the International Conference on Innovative Intelligent Industrial Production and Logistics IN4PL - Volume 1</i>, edited by H. Panetto et al., SCITEPRESS - Science and Technology Publications, 2020, pp. 87–92, <a href=\"https://doi.org/10.5220/0010130300870092\">https://doi.org/10.5220/0010130300870092</a>."},"publication_status":"published","language":[{"iso":"eng"}],"date_created":"2025-04-17T06:20:07Z","author":[{"first_name":"Fabian","last_name":"Berns","full_name":"Berns, Fabian"},{"first_name":"Markus","full_name":"Lange-Hegermann, Markus","id":"71761","last_name":"Lange-Hegermann"},{"first_name":"Christian","full_name":"Beecks, Christian","last_name":"Beecks"}],"publication_identifier":{"isbn":["978-989-758-476-3"]},"abstract":[{"lang":"eng","text":"Discerning unexpected from expected data patterns is the key challenge of anomaly detection. Although a multitude of solutions has been applied to this modern Industry 4.0 problem, it remains an open research issue to identify the key characteristics subjacent to an anomaly, sc. generate hypothesis as to why they appear. In recent years, machine learning models have been regarded as universal solution for a wide range of problems. While most of them suffer from non-self-explanatory representations, Gaussian Processes (GPs) deliver interpretable and robust statistical data models, which are able to cope with unreliable, noisy, or partially missing data. Thus, we regard them as a suitable solution for detecting and appropriately representing anomalies and their respective characteristics. In this position paper, we discuss the problem of automatic and interpretable anomaly detection by means of GPs. That is, we elaborate on why GPs are well suited for anomaly detection and what the current challenges are when applying these probabilistic models to large-scale production data."}],"conference":{"start_date":"2020-11-02","end_date":"2020-11-04","name":"International Conference on Innovative Intelligent Industrial Production and Logistics (IN4PL)","location":"Budapest, HUNGARY"},"page":"87-92","keyword":["Anomaly Detection","Gaussian Processes","Explainable Machine Learning","Industry 4.0"],"status":"public","year":"2020","user_id":"83781","department":[{"_id":"DEP5000"}],"doi":"10.5220/0010130300870092","date_updated":"2025-06-26T13:31:38Z","editor":[{"first_name":"H.","last_name":"Panetto","full_name":"Panetto, H."},{"first_name":"K.","last_name":"Madani","full_name":"Madani, K."},{"full_name":"Smirnov, A.","last_name":"Smirnov","first_name":"A."}],"publisher":"SCITEPRESS - Science and Technology Publications","type":"conference_editor_article"},{"place":"Amsterdam [u.a.]","citation":{"ufg":"<b>Vo, Anh Q. u. a.</b>: Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis, in: <i>Journal of Pharmaceutical Sciences</i> 109 (2020), H. 12,  S. 3598–3607.","chicago-de":"Vo, Anh Q., Gerd Kutz, Herman He, Sagar Narala, Suresh Bandari und Michael A. Repka. 2020. Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. <i>Journal of Pharmaceutical Sciences</i> 109, Nr. 12: 3598–3607. doi:<a href=\"https://doi.org/10.1016/j.xphs.2020.09.007\">10.1016/j.xphs.2020.09.007</a>, .","short":"A.Q. Vo, G. Kutz, H. He, S. Narala, S. Bandari, M.A. Repka, Journal of Pharmaceutical Sciences 109 (2020) 3598–3607.","apa":"Vo, A. Q., Kutz, G., He, H., Narala, S., Bandari, S., &#38; Repka, M. A. (2020). Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. <i>Journal of Pharmaceutical Sciences</i>, <i>109</i>(12), 3598–3607. <a href=\"https://doi.org/10.1016/j.xphs.2020.09.007\">https://doi.org/10.1016/j.xphs.2020.09.007</a>","mla":"Vo, Anh Q., et al. “Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis.” <i>Journal of Pharmaceutical Sciences</i>, vol. 109, no. 12, 2020, pp. 3598–607, <a href=\"https://doi.org/10.1016/j.xphs.2020.09.007\">https://doi.org/10.1016/j.xphs.2020.09.007</a>.","havard":"A.Q. Vo, G. Kutz, H. He, S. Narala, S. Bandari, M.A. Repka, Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis, Journal of Pharmaceutical Sciences. 109 (2020) 3598–3607.","chicago":"Vo, Anh Q., Gerd Kutz, Herman He, Sagar Narala, Suresh Bandari, and Michael A. Repka. “Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis.” <i>Journal of Pharmaceutical Sciences</i> 109, no. 12 (2020): 3598–3607. <a href=\"https://doi.org/10.1016/j.xphs.2020.09.007\">https://doi.org/10.1016/j.xphs.2020.09.007</a>.","bjps":"<b>Vo AQ <i>et al.</i></b> (2020) Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. <i>Journal of Pharmaceutical Sciences</i> <b>109</b>, 3598–3607.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Vo, Anh Q.</span> ; <span style=\"font-variant:small-caps;\">Kutz, Gerd</span> ; <span style=\"font-variant:small-caps;\">He, Herman</span> ; <span style=\"font-variant:small-caps;\">Narala, Sagar</span> ; <span style=\"font-variant:small-caps;\">Bandari, Suresh</span> ; <span style=\"font-variant:small-caps;\">Repka, Michael A.</span>: Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. In: <i>Journal of Pharmaceutical Sciences</i> Bd. 109. Amsterdam [u.a.], Elsevier BV (2020), Nr. 12, S. 3598–3607","ama":"Vo AQ, Kutz G, He H, Narala S, Bandari S, Repka MA. Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. <i>Journal of Pharmaceutical Sciences</i>. 2020;109(12):3598-3607. doi:<a href=\"https://doi.org/10.1016/j.xphs.2020.09.007\">10.1016/j.xphs.2020.09.007</a>","van":"Vo AQ, Kutz G, He H, Narala S, Bandari S, Repka MA. Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis. Journal of Pharmaceutical Sciences. 2020;109(12):3598–607.","ieee":"A. Q. Vo, G. Kutz, H. He, S. Narala, S. Bandari, and M. A. Repka, “Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis,” <i>Journal of Pharmaceutical Sciences</i>, vol. 109, no. 12, pp. 3598–3607, 2020, doi: <a href=\"https://doi.org/10.1016/j.xphs.2020.09.007\">10.1016/j.xphs.2020.09.007</a>."},"date_created":"2025-04-23T08:40:12Z","language":[{"iso":"eng"}],"publication_status":"published","volume":109,"isi":"1","intvolume":"       109","author":[{"full_name":"Vo, Anh Q.","last_name":"Vo","first_name":"Anh Q."},{"last_name":"Kutz","id":"12015","full_name":"Kutz, Gerd","first_name":"Gerd"},{"last_name":"He","full_name":"He, Herman","first_name":"Herman"},{"first_name":"Sagar","full_name":"Narala, Sagar","last_name":"Narala"},{"first_name":"Suresh","full_name":"Bandari, Suresh","last_name":"Bandari"},{"first_name":"Michael A.","last_name":"Repka","full_name":"Repka, Michael A."}],"publication_identifier":{"eissn":["1520-6017"],"issn":["0022-3549"]},"title":"Continuous Manufacturing of Ketoprofen Delayed Release Pellets Using Melt Extrusion Technology: Application of QbD Design Space, Inline Near Infrared, and Inline Pellet Size Analysis","publication":"Journal of Pharmaceutical Sciences","_id":"12835","publisher":"Elsevier BV","type":"scientific_journal_article","doi":"10.1016/j.xphs.2020.09.007","date_updated":"2025-06-26T13:25:32Z","external_id":{"isi":["000590406100010"]},"issue":"12","status":"public","user_id":"83781","year":"2020","department":[{"_id":"DEP4028"}],"abstract":[{"text":"Delayed-release dosage forms are mainly manufactured as batch processes and include coated tablets, pellets, or particles with gastric resistant polymers. Authors propose a novel approach using the hot-melt extrusion technique to prepare delayed release dosage forms via a continuous manufacturing process, a new trend in the pharmaceutical industry. A full factorial design was employed to correlate input variables, including stearic acid (SA) content, drug content, and pellet size with drug release properties of the pellets. PLS fit method suitably elaborated the relationship between input and output variables with reasonably good fit and goodness of prediction. All three input factors influenced drug release in enzyme-free simulated gastric fluid (SGF) after 120 min; however, SA content did not significantly affect drug dissolution in the enzyme-free simulated intestinal fluid (SIF). An optimized formulation and design space were determined by overlaying multiple contours established from regression equations. The continuous manufacturing process was successfully monitored using inline near-infrared (NIR) and inline particle size analysis, with drug load and pellet size being well-controlled within the design space. The obtained pellets released less than 5% after 120 min in SGF and more than 85% and 95% after 30 min and 45 min, respectively, after switching to SIF. (C) 2020 American Pharmacists Association (R). Published by Elsevier Inc. All rights reserved.","lang":"eng"}],"page":"3598-3607","keyword":["Continuous manufacturing","Delayed-release","FT-NIR","Inline particle size analysis","Hot melt extrusion"]},{"publication":"Proceedings of the 15th International Audio Mostly Conference","_id":"12857","language":[{"iso":"eng"}],"date_created":"2025-04-24T07:46:39Z","publication_status":"published","place":"New York, NY","citation":{"ufg":"<b>Berndt, Axel u. a.</b>: Inside Beethoven!, hg. von Groß-Vogt, Katharina, New York, NY 2020.","chicago-de":"Berndt, Axel, Simon Waloschek, Aristotelis Hadjakos und Joachim Veit. 2020. <i>Inside Beethoven!</i> Hg. von Katharina  Groß-Vogt. <i>Proceedings of the 15th International Audio Mostly Conference</i>. New York, NY: ACM. doi:<a href=\"https://doi.org/10.1145/3411109.3411115\">10.1145/3411109.3411115</a>, .","short":"A. Berndt, S. Waloschek, A. Hadjakos, J. Veit, Inside Beethoven!, ACM, New York, NY, 2020.","mla":"Berndt, Axel, et al. “Inside Beethoven!” <i>Proceedings of the 15th International Audio Mostly Conference</i>, edited by Katharina  Groß-Vogt, ACM, 2020, pp. 245–48, <a href=\"https://doi.org/10.1145/3411109.3411115\">https://doi.org/10.1145/3411109.3411115</a>.","apa":"Berndt, A., Waloschek, S., Hadjakos, A., &#38; Veit, J. (2020). Inside Beethoven! In K. Groß-Vogt (Ed.), <i>Proceedings of the 15th International Audio Mostly Conference</i> (pp. 245–248). ACM. <a href=\"https://doi.org/10.1145/3411109.3411115\">https://doi.org/10.1145/3411109.3411115</a>","havard":"A. Berndt, S. Waloschek, A. Hadjakos, J. Veit, Inside Beethoven!, ACM, New York, NY, 2020.","chicago":"Berndt, Axel, Simon Waloschek, Aristotelis Hadjakos, and Joachim Veit. <i>Inside Beethoven!</i> Edited by Katharina  Groß-Vogt. <i>Proceedings of the 15th International Audio Mostly Conference</i>. New York, NY: ACM, 2020. <a href=\"https://doi.org/10.1145/3411109.3411115\">https://doi.org/10.1145/3411109.3411115</a>.","bjps":"<b>Berndt A <i>et al.</i></b> (2020) <i>Inside Beethoven!</i>, Groß-Vogt K (ed.). New York, NY: ACM.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Berndt, Axel</span> ; <span style=\"font-variant:small-caps;\">Waloschek, Simon</span> ; <span style=\"font-variant:small-caps;\">Hadjakos, Aristotelis</span> ; <span style=\"font-variant:small-caps;\">Veit, Joachim</span> ; <span style=\"font-variant:small-caps;\">Groß-Vogt, K.</span> (Hrsg.): <i>Inside Beethoven!</i> New York, NY : ACM, 2020","ama":"Berndt A, Waloschek S, Hadjakos A, Veit J. <i>Inside Beethoven!</i> (Groß-Vogt K, ed.). ACM; 2020:245-248. doi:<a href=\"https://doi.org/10.1145/3411109.3411115\">10.1145/3411109.3411115</a>","van":"Berndt A, Waloschek S, Hadjakos A, Veit J. Inside Beethoven! Groß-Vogt K, editor. Proceedings of the 15th International Audio Mostly Conference. New York, NY: ACM; 2020.","ieee":"A. Berndt, S. Waloschek, A. Hadjakos, and J. Veit, <i>Inside Beethoven!</i> New York, NY: ACM, 2020, pp. 245–248. doi: <a href=\"https://doi.org/10.1145/3411109.3411115\">10.1145/3411109.3411115</a>."},"publication_identifier":{"isbn":["978-1-4503-7563-4"]},"author":[{"full_name":"Berndt, Axel","last_name":"Berndt","first_name":"Axel"},{"first_name":"Simon","full_name":"Waloschek, Simon","last_name":"Waloschek"},{"last_name":"Hadjakos","id":"58704","full_name":"Hadjakos, Aristotelis","first_name":"Aristotelis"},{"last_name":"Veit","full_name":"Veit, Joachim","first_name":"Joachim"}],"title":"Inside Beethoven!","alternative_title":["a musical installation for a new listening perspective"],"status":"public","department":[{"_id":"DEP2000"}],"year":"2020","user_id":"83781","conference":{"location":"Graz, AUSTRIA","name":"15th International Audio Mostly Conference (AM)","start_date":"2020-09-15","end_date":"2020-09-17"},"page":"245-248","abstract":[{"text":"On the occasion of the 250th anniversary celebrations of Ludwig van Beethoven in 2020, we developed the musical room installation \"Inside Beethoven! The Audience Goes on Stage\". It is a stage with virtual musicians. Visitors are invited to enter, take the position of the musicians and listen to each of them at close range. The installation emulates the listening perspective of the musicians, thus, providing an uncommon experience to visitors who are mostly used to listen to music from recordings or from a concert audience's perspective. The musicians play Beethoven's septet op. 20 and its trio arrangement op. 38, two exclusive 14 channel music productions. Both versions are aligned and can be switched seamlessly. Digital music stands visualize the score. In this paper we trace the genesis and construction of the installation and point at some conceptual and technical challenges tackled.","lang":"eng"}],"keyword":["Beethoven","Music","Artistic Installation"],"publisher":"ACM","editor":[{"first_name":"Katharina ","full_name":"Groß-Vogt, Katharina ","last_name":"Groß-Vogt"}],"type":"conference_editor_article","doi":"10.1145/3411109.3411115","date_updated":"2025-06-26T09:01:06Z"},{"title":"Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland","date_created":"2025-06-15T10:01:12Z","language":[{"iso":"ger"}],"volume":48,"publication_status":"published","place":"Stuttgart","citation":{"van":"Geisen V, Mayer C, Harrer J, Hartmann K, Ulrich S, Unterer S. Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland. Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere. 2020;48(05):369–75.","ama":"Geisen V, Mayer C, Harrer J, Hartmann K, Ulrich S, Unterer S. Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland. <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i>. 2020;48(05):369-375. doi:<a href=\"https://doi.org/10.1055/a-1238-1554\">10.1055/a-1238-1554</a>","ieee":"V. Geisen, C. Mayer, J. Harrer, K. Hartmann, S. Ulrich, and S. Unterer, “Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland,” <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i>, vol. 48, no. 05, pp. 369–375, 2020, doi: <a href=\"https://doi.org/10.1055/a-1238-1554\">10.1055/a-1238-1554</a>.","chicago":"Geisen, Vera, Christian Mayer, Julia Harrer, Katrin Hartmann, Sebastian Ulrich, and Stefan Unterer. “Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland.” <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i> 48, no. 05 (2020): 369–75. <a href=\"https://doi.org/10.1055/a-1238-1554\">https://doi.org/10.1055/a-1238-1554</a>.","bjps":"<b>Geisen V <i>et al.</i></b> (2020) Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland. <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i> <b>48</b>, 369–375.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Geisen, Vera</span> ; <span style=\"font-variant:small-caps;\">Mayer, Christian</span> ; <span style=\"font-variant:small-caps;\">Harrer, Julia</span> ; <span style=\"font-variant:small-caps;\">Hartmann, Katrin</span> ; <span style=\"font-variant:small-caps;\">Ulrich, Sebastian</span> ; <span style=\"font-variant:small-caps;\">Unterer, Stefan</span>: Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland. In: <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i> Bd. 48. Stuttgart, Thieme  (2020), Nr. 05, S. 369–375","havard":"V. Geisen, C. Mayer, J. Harrer, K. Hartmann, S. Ulrich, S. Unterer, Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland, Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere. 48 (2020) 369–375.","ufg":"<b>Geisen, Vera u. a.</b>: Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland, in: <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i> 48 (2020), H. 05,  S. 369–375.","chicago-de":"Geisen, Vera, Christian Mayer, Julia Harrer, Katrin Hartmann, Sebastian Ulrich und Stefan Unterer. 2020. Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland. <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i> 48, Nr. 05: 369–375. doi:<a href=\"https://doi.org/10.1055/a-1238-1554\">10.1055/a-1238-1554</a>, .","short":"V. Geisen, C. Mayer, J. Harrer, K. Hartmann, S. Ulrich, S. Unterer, Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere 48 (2020) 369–375.","mla":"Geisen, Vera, et al. “Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland.” <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i>, vol. 48, no. 05, 2020, pp. 369–75, <a href=\"https://doi.org/10.1055/a-1238-1554\">https://doi.org/10.1055/a-1238-1554</a>.","apa":"Geisen, V., Mayer, C., Harrer, J., Hartmann, K., Ulrich, S., &#38; Unterer, S. (2020). Ulzerative granulomatöse Kolitis durch Prototheca spp. bei einem Rhodesian Ridgeback in Deutschland. <i>Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere</i>, <i>48</i>(05), 369–375. <a href=\"https://doi.org/10.1055/a-1238-1554\">https://doi.org/10.1055/a-1238-1554</a>"},"publication_identifier":{"issn":["1434-1239"],"eissn":["2567-5842"]},"intvolume":"        48","author":[{"first_name":"Vera","last_name":"Geisen","full_name":"Geisen, Vera"},{"last_name":"Mayer","full_name":"Mayer, Christian","first_name":"Christian"},{"first_name":"Julia","last_name":"Harrer","full_name":"Harrer, Julia"},{"first_name":"Katrin","last_name":"Hartmann","full_name":"Hartmann, Katrin"},{"full_name":"Ulrich, Sebastian","last_name":"Ulrich","id":"85847","first_name":"Sebastian","orcid":"0000-0002-4511-9537"},{"first_name":"Stefan","last_name":"Unterer","full_name":"Unterer, Stefan"}],"_id":"12955","publication":"Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere","date_updated":"2025-06-18T12:24:09Z","doi":"10.1055/a-1238-1554","issue":"05","publisher":"Thieme ","type":"scientific_journal_article","page":"369-375","abstract":[{"text":"Ein 10 Monate alter, männlich intakter Rhodesian Ridgeback wurde wegen chronischen Dickdarmdurchfalls und Hämatochezie vorgestellt. Der Hund stammte aus Deutschland und hatte das Land nie verlassen. Die Laboruntersuchung des vorbehandelnden Tierarztes ergab neben einer Neutrophilie eine Hyperkaliämie und eine Hyponatriämie. Mit einem Serumbasalkortisolwert von 4,3 µg/dl konnte ein Hypoadrenokortizismus weitgehend ausgeschlossen werden. Eine vom Tierarzt durch geführte antibiotische Behandlung hatte keine Besserung bewirkt. Daher war der Hund mit Prednisolon behandelt worden. Unter 2-wöchiger Prednisolongabe kam es zu einer deutlichen Verstärkung des Durchfalls sowie einem Gewichtsverlust von 6 kg. Bei Vorstellung an der Medizinischen Kleintierklinik der LMU München war der Hund im Allgemeinbefinden mittelgradig reduziert, deutlich abgemagert, dehydriert, hypovolämisch und hatte eine rektale Körpertemperatur von 39,6 °C. Bei der sonografischen Untersuchung zeigte sich eine generalisiert verdickte Dickdarmwand und koloskopisch eine hochgradig ulzerativ veränderte Dickdarmschleimhaut. Histologischer Befund war eine ulzerative granulomatöse Kolitis. Durch die Periodic-Acid-Schiff-Reaktion ließen sich in den Schnitten der Dickdarmbioptate mikrobielle Strukturen darstellen, die für eine Algeninfektion diagnostisch waren. Die bei der mikrobiellen Untersuchung anzüchtbaren Prototheken wurden mittels MALDI-TOF-MS als Prototheca zopfii identifiziert. Zum Nachweis einer möglichen Immundefizienz wurden die Immunglobuline im Serum bestimmt. Die IgM-Konzentration war erniedrigt, während sich IgG- und IgA-Konzentration im Referenzbereich befanden. Aufgrund der Verschlechterung des Allgemeinbefindens, der vorsichtigen Prognose und der hohen Kosten eines Therapieversuchs wurde der Hund eine Woche später euthanasiert und der Tierkörper pathologisch untersucht. Histopathologisch wurden Prototheken auch in den abdominalen Lymphknoten, jedoch nicht in den Augen oder im zentralen Nervensystem identifiziert. Der Fall zeigt, dass eine Prototheken-Infektion auch bei Hunden aus Deutschland als Differenzialdiagnose für chronischen Dickdarmdurchfall in Betracht gezogen werden sollte, insbesondere bei Patienten mit ulzerativer granulomatöser Kolitis. Sie kann bei der histologischen Untersuchung ohne Spezialfärbung leicht übersehen werden.","lang":"ger"},{"lang":"eng","text":"A 10-month-old male Rhodesian Ridgeback was presented to the Clinic of Small Animal Medicine, LMU, Germany, with a 6-month history of chronic diarrhea and hematochezia. The dog lived in Germany and had never traveled abroad. Complete blood count and serum biochemistry performed by the referring veterinarian revealed neutrophilia, hyperkalemia, and hyponatremia, with a basal cortisol of 4.3 µg/dl, which excluded hypoadrenocorticism. Since antibiotic treatment had not resulted in any improvement, a 2 week course of prednisolone administration had been initiated, leading to a marked deterioration of intestinal signs and a significant weight loss of 6 kg. At the time of referral, the patient was markedly emaciated, dehydrated, hypovolemic and had a rectal temperature of 39.6 °C. Abdominal ultrasound showed a thickened and irregular colonic wall. On colonoscopy, an irregular colonic mucosa with ulcerations was observed. Histopathologic examination revealed an ulcerative granulomatous colitis, and on Periodic acid-Schiff reaction (PAS) numerous organisms consistent with Prototheca spp. were identified. Prototheca zopfii infection was confirmed by culture and MALDI-TOF MS. In order to test for an underlying immunodeficiency, immunoglobulin levels in serum were determined. IgM was decreased, while IgG and IgA levels were within the reference interval. Due to deterioration of general condition, grave prognosis and costs of a treatment trial, the patient was euthanized one week later, and necropsy was performed. Prototheca spp. were detected on histopathologic examination in the lymphnodes, however not in the eyes or the central nervous system. Protothecosis should be considered an differential diagnosis in dogs with chronic diarrhea and ulcerative granulomatous colitis even in dogs living in Germany. Histopathologic examination of colonic biopsies with special stains such as PAS is recommended in every dog with signs of chronic large bowel disease in order to avoid missing this rare infectious disease."}],"keyword":["Hund - Algeninfektion - chronischer Durchfall - Protothekose - Prototheca zopfii"],"extern":"1","status":"public","department":[{"_id":"DEP4010"}],"user_id":"83781","year":"2020"},{"status":"public","year":"2020","user_id":"83781","department":[{"_id":"DEP4010"}],"abstract":[{"text":"Stachybotrys (S.) chartarum had been linked to severe health problems in humans and animals, which occur after exposure to the toxic secondary metabolites of this mold. S. chartarum had been isolated from different environmental sources, ranging from culinary herbs and improperly stored fodder to damp building materials. To access the pathogenic potential of isolates, it is essential to analyze them under defined conditions that allow for the production of their toxic metabolites. All Stachybotrys species are assumed to produce the immunosuppressive phenylspirodrimanes, but the highly cytotoxic macrocyclic trichothecenes are exclusively generated by the genotype S of S. chartarum. In this study, we have analyzed four genotype S strains initially isolated from three different habitats. We grew them on five commonly used media (malt-extract-agar, glucose-yeast-peptone-agar, potato-dextrose-agar, cellulose-agar, Sabouraud-dextrose-agar) to identify conditions that promote mycotoxin production. Using LC-MS/MS, we have quantified stachybotrylactam and all S-type specific macrocyclic trichothecenes (satratoxin G, H, F, roridin E, L-2, verrucarin J). All five media supported a comparable fungal growth and sporulation at 25 °C in the dark. The highest concentrations of macrocyclic trichothecenes were detected on potato-dextrose-agar or cellulose-agar. Malt-extract-agar let to an intermediate and glucose-yeast-peptone-agar and Sabouraud-dextrose-agar to a poor mycotoxin production. These data demonstrate that the mycotoxin production clearly depends on the composition of the respective medium. Our findings provide a starting point for further studies in order to identify individual components that either support or repress the production of mycotoxins in S. chartarum.","lang":"eng"}],"extern":"1","keyword":["Stachybotrys","genotype","macrocyclic trichothecenes","stachybotrylactam"],"publisher":"MDPI ","type":"scientific_journal_article","doi":"10.3390/jof6030159","date_updated":"2025-06-16T13:59:56Z","quality_controlled":"1","issue":"3","publication":"Journal of Fungi","article_number":"159","_id":"12956","place":"Basel","citation":{"bjps":"<b>Ulrich S and Schäfer C</b> (2020) Toxin Production by Stachybotrys Chartarum Genotype S on Different Culture Media. <i>Journal of Fungi</i> <b>6</b>.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Ulrich, Sebastian</span> ; <span style=\"font-variant:small-caps;\">Schäfer, Cornelius</span>: Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media. In: <i>Journal of Fungi</i> Bd. 6. Basel, MDPI  (2020), Nr. 3","chicago":"Ulrich, Sebastian, and Cornelius Schäfer. “Toxin Production by Stachybotrys Chartarum Genotype S on Different Culture Media.” <i>Journal of Fungi</i> 6, no. 3 (2020). <a href=\"https://doi.org/10.3390/jof6030159\">https://doi.org/10.3390/jof6030159</a>.","ieee":"S. Ulrich and C. Schäfer, “Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media,” <i>Journal of Fungi</i>, vol. 6, no. 3, Art. no. 159, 2020, doi: <a href=\"https://doi.org/10.3390/jof6030159\">10.3390/jof6030159</a>.","ama":"Ulrich S, Schäfer C. Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media. <i>Journal of Fungi</i>. 2020;6(3). doi:<a href=\"https://doi.org/10.3390/jof6030159\">10.3390/jof6030159</a>","van":"Ulrich S, Schäfer C. Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media. Journal of Fungi. 2020;6(3).","short":"S. Ulrich, C. Schäfer, Journal of Fungi 6 (2020).","apa":"Ulrich, S., &#38; Schäfer, C. (2020). Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media. <i>Journal of Fungi</i>, <i>6</i>(3), Article 159. <a href=\"https://doi.org/10.3390/jof6030159\">https://doi.org/10.3390/jof6030159</a>","mla":"Ulrich, Sebastian, and Cornelius Schäfer. “Toxin Production by Stachybotrys Chartarum Genotype S on Different Culture Media.” <i>Journal of Fungi</i>, vol. 6, no. 3, 159, 2020, <a href=\"https://doi.org/10.3390/jof6030159\">https://doi.org/10.3390/jof6030159</a>.","ufg":"<b>Ulrich, Sebastian/Schäfer, Cornelius</b>: Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media, in: <i>Journal of Fungi</i> 6 (2020), H. 3.","chicago-de":"Ulrich, Sebastian und Cornelius Schäfer. 2020. Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media. <i>Journal of Fungi</i> 6, Nr. 3. doi:<a href=\"https://doi.org/10.3390/jof6030159\">10.3390/jof6030159</a>, .","havard":"S. Ulrich, C. Schäfer, Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media, Journal of Fungi. 6 (2020)."},"language":[{"iso":"eng"}],"date_created":"2025-06-15T10:01:42Z","publication_status":"published","volume":6,"intvolume":"         6","author":[{"first_name":"Sebastian","id":"85847","last_name":"Ulrich","full_name":"Ulrich, Sebastian","orcid":"0000-0002-4511-9537"},{"first_name":"Cornelius","full_name":"Schäfer, Cornelius","last_name":"Schäfer"}],"publication_identifier":{"eissn":["2309-608X"]},"title":"Toxin Production by Stachybotrys chartarum Genotype S on Different Culture Media"},{"publication_identifier":{"issn":["1756-3305"]},"author":[{"last_name":"Liang","full_name":"Liang, Liucun","first_name":"Liucun"},{"full_name":"Wang, Jinyong","last_name":"Wang","first_name":"Jinyong"},{"full_name":"Schorter, Lucas","last_name":"Schorter","first_name":"Lucas"},{"first_name":"Thu Phong","last_name":"Nguyen Trong","full_name":"Nguyen Trong, Thu Phong"},{"last_name":"Fell","full_name":"Fell, Shari","first_name":"Shari"},{"orcid":"0000-0002-4511-9537","full_name":"Ulrich, Sebastian","id":"85847","last_name":"Ulrich","first_name":"Sebastian"},{"last_name":"Straubinger","full_name":"Straubinger, Reinhard K.","first_name":"Reinhard K."}],"intvolume":"        13","language":[{"iso":"eng"}],"date_created":"2025-06-15T10:13:30Z","publication_status":"published","volume":13,"place":"London","citation":{"bjps":"<b>Liang L <i>et al.</i></b> (2020) Rapid Clearance of Borrelia Burgdorferi from the Blood Circulation. <i>Parasites &#38; vectors</i> <b>13</b>.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Liang, Liucun</span> ; <span style=\"font-variant:small-caps;\">Wang, Jinyong</span> ; <span style=\"font-variant:small-caps;\">Schorter, Lucas</span> ; <span style=\"font-variant:small-caps;\">Nguyen Trong, Thu Phong</span> ; <span style=\"font-variant:small-caps;\">Fell, Shari</span> ; <span style=\"font-variant:small-caps;\">Ulrich, Sebastian</span> ; <span style=\"font-variant:small-caps;\">Straubinger, Reinhard K.</span>: Rapid clearance of Borrelia burgdorferi from the blood circulation. In: <i>Parasites &#38; vectors</i> Bd. 13. London, BioMed Central  (2020), Nr. 1","chicago":"Liang, Liucun, Jinyong Wang, Lucas Schorter, Thu Phong Nguyen Trong, Shari Fell, Sebastian Ulrich, and Reinhard K. Straubinger. “Rapid Clearance of Borrelia Burgdorferi from the Blood Circulation.” <i>Parasites &#38; Vectors</i> 13, no. 1 (2020). <a href=\"https://doi.org/10.1186/s13071-020-04060-y\">https://doi.org/10.1186/s13071-020-04060-y</a>.","ieee":"L. Liang <i>et al.</i>, “Rapid clearance of Borrelia burgdorferi from the blood circulation,” <i>Parasites &#38; vectors</i>, vol. 13, no. 1, Art. no. 191, 2020, doi: <a href=\"https://doi.org/10.1186/s13071-020-04060-y\">10.1186/s13071-020-04060-y</a>.","van":"Liang L, Wang J, Schorter L, Nguyen Trong TP, Fell S, Ulrich S, et al. Rapid clearance of Borrelia burgdorferi from the blood circulation. Parasites &#38; vectors. 2020;13(1).","ama":"Liang L, Wang J, Schorter L, et al. Rapid clearance of Borrelia burgdorferi from the blood circulation. <i>Parasites &#38; vectors</i>. 2020;13(1). doi:<a href=\"https://doi.org/10.1186/s13071-020-04060-y\">10.1186/s13071-020-04060-y</a>","short":"L. Liang, J. Wang, L. Schorter, T.P. Nguyen Trong, S. Fell, S. Ulrich, R.K. Straubinger, Parasites &#38; Vectors 13 (2020).","mla":"Liang, Liucun, et al. “Rapid Clearance of Borrelia Burgdorferi from the Blood Circulation.” <i>Parasites &#38; Vectors</i>, vol. 13, no. 1, 191, 2020, <a href=\"https://doi.org/10.1186/s13071-020-04060-y\">https://doi.org/10.1186/s13071-020-04060-y</a>.","apa":"Liang, L., Wang, J., Schorter, L., Nguyen Trong, T. P., Fell, S., Ulrich, S., &#38; Straubinger, R. K. (2020). Rapid clearance of Borrelia burgdorferi from the blood circulation. <i>Parasites &#38; Vectors</i>, <i>13</i>(1), Article 191. <a href=\"https://doi.org/10.1186/s13071-020-04060-y\">https://doi.org/10.1186/s13071-020-04060-y</a>","ufg":"<b>Liang, Liucun u. a.</b>: Rapid clearance of Borrelia burgdorferi from the blood circulation, in: <i>Parasites &#38; vectors</i> 13 (2020), H. 1.","chicago-de":"Liang, Liucun, Jinyong Wang, Lucas Schorter, Thu Phong Nguyen Trong, Shari Fell, Sebastian Ulrich und Reinhard K. Straubinger. 2020. Rapid clearance of Borrelia burgdorferi from the blood circulation. <i>Parasites &#38; vectors</i> 13, Nr. 1. doi:<a href=\"https://doi.org/10.1186/s13071-020-04060-y\">10.1186/s13071-020-04060-y</a>, .","havard":"L. Liang, J. Wang, L. Schorter, T.P. Nguyen Trong, S. Fell, S. Ulrich, R.K. Straubinger, Rapid clearance of Borrelia burgdorferi from the blood circulation, Parasites &#38; Vectors. 13 (2020)."},"title":"Rapid clearance of Borrelia burgdorferi from the blood circulation","publication":"Parasites & vectors","_id":"12962","article_number":"191","type":"scientific_journal_article","publisher":"BioMed Central ","issue":"1","quality_controlled":"1","doi":"10.1186/s13071-020-04060-y","date_updated":"2025-06-17T14:17:27Z","department":[{"_id":"DEP4010"}],"year":"2020","user_id":"83781","status":"public","keyword":["Lyme borreliosis","Borrelia burgdorferi","Tick-borne relapsing fever","Borrelia persica","Blood clearance"],"extern":"1","abstract":[{"text":"Background\r\nBorrelia burgdorferi is a tick-borne spirochete that causes Lyme borreliosis (LB). After an initial tick bite, it spreads from the deposition site in the dermis to distant tissues of the host. It is generally believed that this spirochete disseminates via the hematogenous route. Borrelia persica causes relapsing fever and is able to replicate in the blood stream. Currently the exact dissemination pathway of LB pathogens in the host is not known and controversially discussed.\r\nMethods\r\nIn this study, we established a strict intravenous infection murine model using host-adapted spirochetes. Survival capacity and infectivity of host-adapted B. burgdorferi sensu stricto (Bbss) were compared to those of B. persica (Bp) after either intradermal (ID) injection into the dorsal skin of immunocompetent mice or strict intravenous (IV) inoculation via the jugular vein. By in vitro culture and PCR, viable spirochetes and their DNA load in peripheral blood were periodically monitored during a 49/50-day course post-injection, as well as in various tissue samples collected at day 49/50. Specific antibodies in individual plasma/serum samples were detected with serological methods.\r\nResults\r\nRegardless of ID or IV injection, DNA of Bp was present in blood samples up to day 24 post-challenge, while no Bbss was detectable in the blood circulation during the complete observation period. In contrast to the brain tropism of Bp, Bbss spirochetes were found in ear, skin, joint, bladder, and heart tissue samples of only ID-inoculated mice. All tested tissues collected from IV-challenged mice were negative for traces of Bbss. ELISA testing of serum samples showed that Bp induced gradually increasing antibody levels after ID or IV inoculation, while Bbss did so only after ID injection but not after IV inoculation.\r\nConclusions\r\nThis study allows us to draw the following conclusions: (i) Bp survives in the blood and disseminates to the host’s brain via the hematogenous route; and (ii) Bbss, in contrast, is cleared rapidly from the blood stream and is a tissue-bound spirochete.","lang":"eng"}]},{"user_id":"83781","year":"2020","department":[{"_id":"DEP4010"}],"status":"public","extern":"1","keyword":["Borrelia burgdorferi sensu lato","MALDI-TOF MS","typing","sample preparation","MALDI-TOF MS library","strain typing","automatic identification"],"abstract":[{"text":"The genus Borrelia comprises vector-borne bacterial pathogens that can severely affect human and animal health. Members of the Borrelia burgdorferi sensu lato species complex can cause Lyme borreliosis, one of the most common vector-borne diseases in the Northern hemisphere. Besides, members of the relapsing fever group of spirochetes can cause tick-borne relapsing fever in humans and various febrile illnesses in animals in tropical, subtropical and temperate regions. Borrelia spp. organisms are fastidious to cultivate and to maintain in vitro, and therefore, difficult to work with in the laboratory. Currently, borrelia identification is mainly performed using PCR and DNA sequencing methods, which can be complicated/frustrating on complex DNA templates and may still be relatively expensive. Alternative techniques such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) are not well established for Borrelia spp., although this technique is currently one of the most used techniques for rapid identification of bacteria in microbiological diagnostic laboratories. This is mainly due to unsatisfactory results obtained by use of simple sample preparation techniques and medium-contamination obscuring the mass spectra. In addition, comprehensive libraries for Borrelia spp. MALDI-TOF MS have yet to be established. In this study, we developed a new filter-based chemical extraction technique that allows measurement of high quality Borrelia spp. spectra from less than 100,000 bacteria per spot in MALDI-TOF MS. We used 49 isolates of 13 different species to produce the largest mass-library for Borrelia spp. so far and to validate the protocol. The library was successfully established and identifies >96% of used isolates correctly to species level. Cluster analysis on the sum spectra was applied to all the different isolates, which resulted in tight cluster generation for most species. Comparative analysis of the generated cluster to a phylogeny based on concatenated multi-locus sequence typing genes provided a surprising homology. Our data demonstrate that the technique described here can be used for fast and reliable species and strain typing within the borrelia complex.","lang":"eng"}],"type":"scientific_journal_article","publisher":"Frontiers Media SA","doi":"10.3389/fmicb.2020.00690","date_updated":"2025-06-18T11:09:40Z","quality_controlled":"1","publication":"Frontiers in Microbiology","_id":"12963","author":[{"full_name":"Neumann-Cip, Anna-Cathrine","last_name":"Neumann-Cip","first_name":"Anna-Cathrine"},{"last_name":"Fingerle","full_name":"Fingerle, Volker","first_name":"Volker"},{"first_name":"Gabriele","last_name":"Margos","full_name":"Margos, Gabriele"},{"last_name":"Straubinger","full_name":"Straubinger, Reinhard K.","first_name":"Reinhard K."},{"first_name":"Evelyn","full_name":"Overzier, Evelyn","last_name":"Overzier"},{"orcid":"0000-0002-4511-9537","first_name":"Sebastian","full_name":"Ulrich, Sebastian","last_name":"Ulrich","id":"85847"},{"first_name":"Andreas","last_name":"Wieser","full_name":"Wieser, Andreas"}],"intvolume":"        11","publication_identifier":{"eissn":["1664-302X"]},"place":"Lausanne","citation":{"bjps":"<b>Neumann-Cip A-C <i>et al.</i></b> (2020) A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia Burgdorferi Sensu Lato Species and Isolate Differentiation. <i>Frontiers in Microbiology</i> <b>11</b>.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Neumann-Cip, Anna-Cathrine</span> ; <span style=\"font-variant:small-caps;\">Fingerle, Volker</span> ; <span style=\"font-variant:small-caps;\">Margos, Gabriele</span> ; <span style=\"font-variant:small-caps;\">Straubinger, Reinhard K.</span> ; <span style=\"font-variant:small-caps;\">Overzier, Evelyn</span> ; <span style=\"font-variant:small-caps;\">Ulrich, Sebastian</span> ; <span style=\"font-variant:small-caps;\">Wieser, Andreas</span>: A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation. In: <i>Frontiers in Microbiology</i> Bd. 11. Lausanne, Frontiers Media SA (2020)","chicago":"Neumann-Cip, Anna-Cathrine, Volker Fingerle, Gabriele Margos, Reinhard K. Straubinger, Evelyn Overzier, Sebastian Ulrich, and Andreas Wieser. “A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia Burgdorferi Sensu Lato Species and Isolate Differentiation.” <i>Frontiers in Microbiology</i> 11 (2020). <a href=\"https://doi.org/10.3389/fmicb.2020.00690\">https://doi.org/10.3389/fmicb.2020.00690</a>.","ieee":"A.-C. Neumann-Cip <i>et al.</i>, “A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation,” <i>Frontiers in Microbiology</i>, vol. 11, 2020, doi: <a href=\"https://doi.org/10.3389/fmicb.2020.00690\">10.3389/fmicb.2020.00690</a>.","ama":"Neumann-Cip AC, Fingerle V, Margos G, et al. A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation. <i>Frontiers in Microbiology</i>. 2020;11. doi:<a href=\"https://doi.org/10.3389/fmicb.2020.00690\">10.3389/fmicb.2020.00690</a>","van":"Neumann-Cip AC, Fingerle V, Margos G, Straubinger RK, Overzier E, Ulrich S, et al. A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation. Frontiers in Microbiology. 2020;11.","short":"A.-C. Neumann-Cip, V. Fingerle, G. Margos, R.K. Straubinger, E. Overzier, S. Ulrich, A. Wieser, Frontiers in Microbiology 11 (2020).","mla":"Neumann-Cip, Anna-Cathrine, et al. “A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia Burgdorferi Sensu Lato Species and Isolate Differentiation.” <i>Frontiers in Microbiology</i>, vol. 11, 2020, <a href=\"https://doi.org/10.3389/fmicb.2020.00690\">https://doi.org/10.3389/fmicb.2020.00690</a>.","apa":"Neumann-Cip, A.-C., Fingerle, V., Margos, G., Straubinger, R. K., Overzier, E., Ulrich, S., &#38; Wieser, A. (2020). A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation. <i>Frontiers in Microbiology</i>, <i>11</i>. <a href=\"https://doi.org/10.3389/fmicb.2020.00690\">https://doi.org/10.3389/fmicb.2020.00690</a>","ufg":"<b>Neumann-Cip, Anna-Cathrine u. a.</b>: A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation, in: <i>Frontiers in Microbiology</i> 11 (2020).","chicago-de":"Neumann-Cip, Anna-Cathrine, Volker Fingerle, Gabriele Margos, Reinhard K. Straubinger, Evelyn Overzier, Sebastian Ulrich und Andreas Wieser. 2020. A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation. <i>Frontiers in Microbiology</i> 11. doi:<a href=\"https://doi.org/10.3389/fmicb.2020.00690\">10.3389/fmicb.2020.00690</a>, .","havard":"A.-C. Neumann-Cip, V. Fingerle, G. Margos, R.K. Straubinger, E. Overzier, S. Ulrich, A. Wieser, A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation, Frontiers in Microbiology. 11 (2020)."},"date_created":"2025-06-15T10:15:09Z","language":[{"iso":"eng"}],"publication_status":"published","volume":11,"title":"A Novel Rapid Sample Preparation Method for MALDI-TOF MS Permits Borrelia burgdorferi Sensu Lato Species and Isolate Differentiation"},{"intvolume":"         6","author":[{"orcid":"0000-0002-4511-9537","id":"85847","last_name":"Ulrich","full_name":"Ulrich, Sebastian","first_name":"Sebastian"},{"first_name":"Frank","full_name":"Ebel, Frank","last_name":"Ebel"}],"publication_identifier":{"eissn":["2309-608X"]},"citation":{"apa":"Ulrich, S., &#38; Ebel, F. (2020). Monoclonal Antibodies as Tools to Combat Fungal Infections. <i>Journal of Fungi</i>, <i>6</i>(1), Article 22. <a href=\"https://doi.org/10.3390/jof6010022\">https://doi.org/10.3390/jof6010022</a>","mla":"Ulrich, Sebastian, and Frank Ebel. “Monoclonal Antibodies as Tools to Combat Fungal Infections.” <i>Journal of Fungi</i>, vol. 6, no. 1, 22, 2020, <a href=\"https://doi.org/10.3390/jof6010022\">https://doi.org/10.3390/jof6010022</a>.","short":"S. Ulrich, F. Ebel, Journal of Fungi 6 (2020).","chicago-de":"Ulrich, Sebastian und Frank Ebel. 2020. Monoclonal Antibodies as Tools to Combat Fungal Infections. <i>Journal of Fungi</i> 6, Nr. 1. doi:<a href=\"https://doi.org/10.3390/jof6010022\">10.3390/jof6010022</a>, .","ufg":"<b>Ulrich, Sebastian/Ebel, Frank</b>: Monoclonal Antibodies as Tools to Combat Fungal Infections, in: <i>Journal of Fungi</i> 6 (2020), H. 1.","havard":"S. Ulrich, F. Ebel, Monoclonal Antibodies as Tools to Combat Fungal Infections, Journal of Fungi. 6 (2020).","din1505-2-1":"<span style=\"font-variant:small-caps;\">Ulrich, Sebastian</span> ; <span style=\"font-variant:small-caps;\">Ebel, Frank</span>: Monoclonal Antibodies as Tools to Combat Fungal Infections. In: <i>Journal of Fungi</i> Bd. 6. Basel, MDPI  (2020), Nr. 1","bjps":"<b>Ulrich S and Ebel F</b> (2020) Monoclonal Antibodies as Tools to Combat Fungal Infections. <i>Journal of Fungi</i> <b>6</b>.","chicago":"Ulrich, Sebastian, and Frank Ebel. “Monoclonal Antibodies as Tools to Combat Fungal Infections.” <i>Journal of Fungi</i> 6, no. 1 (2020). <a href=\"https://doi.org/10.3390/jof6010022\">https://doi.org/10.3390/jof6010022</a>.","ieee":"S. Ulrich and F. Ebel, “Monoclonal Antibodies as Tools to Combat Fungal Infections,” <i>Journal of Fungi</i>, vol. 6, no. 1, Art. no. 22, 2020, doi: <a href=\"https://doi.org/10.3390/jof6010022\">10.3390/jof6010022</a>.","ama":"Ulrich S, Ebel F. Monoclonal Antibodies as Tools to Combat Fungal Infections. <i>Journal of Fungi</i>. 2020;6(1). doi:<a href=\"https://doi.org/10.3390/jof6010022\">10.3390/jof6010022</a>","van":"Ulrich S, Ebel F. Monoclonal Antibodies as Tools to Combat Fungal Infections. Journal of Fungi. 2020;6(1)."},"place":"Basel","publication_status":"published","volume":6,"language":[{"iso":"eng"}],"date_created":"2025-06-15T10:17:00Z","title":"Monoclonal Antibodies as Tools to Combat Fungal Infections","publication":"Journal of Fungi","_id":"12964","article_number":"22","type":"scientific_journal_article","publisher":"MDPI ","issue":"1","doi":"10.3390/jof6010022","date_updated":"2025-06-18T11:13:40Z","quality_controlled":"1","user_id":"83781","year":"2020","department":[{"_id":"DEP4010"}],"status":"public","extern":"1","keyword":["monoclonal antibodies","invasive fungal infections","therapy","prophylaxis","opsonization"],"abstract":[{"lang":"eng","text":"Antibodies represent an important element in the adaptive immune response and a major tool to eliminate microbial pathogens. For many bacterial and viral infections, efficient vaccines exist, but not for fungal pathogens. For a long time, antibodies have been assumed to be of minor importance for a successful clearance of fungal infections; however this perception has been challenged by a large number of studies over the last three decades. In this review, we focus on the potential therapeutic and prophylactic use of monoclonal antibodies. Since systemic mycoses normally occur in severely immunocompromised patients, a passive immunization using monoclonal antibodies is a promising approach to directly attack the fungal pathogen and/or to activate and strengthen the residual antifungal immune response in these patients."}]},{"date_updated":"2026-02-20T07:09:36Z","title":"TreeTower","citation":{"havard":"L. Konschake, TreeTower, Technische Hochschule Ostwestfalen-Lippe, Detmolder Schule für Gestaltung, 2020.","short":"L. Konschake, TreeTower, Technische Hochschule Ostwestfalen-Lippe, Detmolder Schule für Gestaltung, 2020.","mla":"Konschake, Leon. <i>TreeTower</i>. Technische Hochschule Ostwestfalen-Lippe, 2020.","apa":"Konschake, L. (2020). <i>TreeTower</i>. Technische Hochschule Ostwestfalen-Lippe.","ufg":"<b>Konschake, Leon</b>: TreeTower, Detmolder Schule für Gestaltung 2020.","chicago-de":"Konschake, Leon. 2020. <i>TreeTower</i>. Detmolder Schule für Gestaltung: Technische Hochschule Ostwestfalen-Lippe.","ieee":"L. Konschake, <i>TreeTower</i>. Detmolder Schule für Gestaltung: Technische Hochschule Ostwestfalen-Lippe, 2020.","van":"Konschake L. TreeTower. Detmolder Schule für Gestaltung: Technische Hochschule Ostwestfalen-Lippe; 2020.","ama":"Konschake L. <i>TreeTower</i>. Technische Hochschule Ostwestfalen-Lippe; 2020.","bjps":"<b>Konschake L</b> (2020) <i>TreeTower</i>. Detmolder Schule für Gestaltung: Technische Hochschule Ostwestfalen-Lippe.","din1505-2-1":"<span style=\"font-variant:small-caps;\">Konschake, Leon</span>: <i>TreeTower</i>. Detmolder Schule für Gestaltung : Technische Hochschule Ostwestfalen-Lippe, 2020","chicago":"Konschake, Leon. <i>TreeTower</i>. Detmolder Schule für Gestaltung: Technische Hochschule Ostwestfalen-Lippe, 2020."},"place":"Detmolder Schule für Gestaltung","publication_status":"published","date_created":"2026-02-12T11:47:28Z","publisher":"Technische Hochschule Ostwestfalen-Lippe","language":[{"iso":"eng"}],"author":[{"first_name":"Leon","full_name":"Konschake, Leon","last_name":"Konschake","id":"84541","orcid":"https://orcid.org/0009-0000-5181-1573"}],"type":"bachelor_thesis","abstract":[{"lang":"eng","text":"This bachelor thesis explores the adaptive reuse of the former Telekom high-rise at Kesselbrink in Bielefeld, a vacant modernist office tower awaiting new purpose. The project proposes a mixed-use transformation that reinterprets the building as a “city within the city,” inspired by Le Corbusier’s Unité d’Habitation in Marseille. The existing structure is strategically reduced to its essential load-bearing concrete frame and floor slabs, preserving the structural skeleton while enabling radical spatial reconfiguration.\r\nPrefabricated timber modules are inserted and cantilevered between the reinforced-concrete columns, extending the usable floor area and introducing a warm, contemporary material contrast to the original façade. This intervention not only increases density and flexibility but also redefines the tower’s appearance, giving it a cosmopolitan and forward-looking architectural identity. The ground floor is conceived as an open and publicly accessible urban platform, activating the surrounding plaza and strengthening social interaction. Upper floors are redesigned as affordable and attractive living spaces for young residents, encouraging a diverse and vibrant community within the building.\r\nA newly designed park-like rooftop landscape provides recreational space and panoramic views over the city, enhancing environmental quality and urban connectivity. By combining structural preservation, modular timber construction, public programming, and residential reuse, the proposal demonstrates how high-rise retrofitting can generate social, ecological, and economic value simultaneously. The project positions adaptive reuse as a viable strategy for sustainable urban regeneration and architectural longevity."}],"supervisor":[{"id":"64589","last_name":"Sachs","full_name":"Sachs, Hans","first_name":"Hans"}],"_id":"13372","extern":"1","keyword":["Adaptive Reuse","Mixed-Use Development","High-Rise Transformation","City within the City","Modular Timber Construction","Prefabrication","Structural Preservation","Concrete Skeleton","Cantilevered Modules","Urban Regeneration","Public Ground Floor","Youth Housing","Rooftop Landscape","Sustainability","Social Impact","Ecological Design","Economic Viability","Cosmopolitan Architecture"],"status":"public","year":"2020","user_id":"83781","department":[{"_id":"DEP1600"}]}]
