{"citation":{"ufg":"<b>Tribelhorn, Katharina u. a.</b>: A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam, in: <i>Applied and Environmental Microbiology</i> 89 (2023), H. 7.","ama":"Tribelhorn K, Twarużek M, Kosicki R, Straubinger RK, Ebel F, Ulrich S. A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam. <i>Applied and Environmental Microbiology</i>. 2023;89(7). doi:<a href=\"https://doi.org/10.1128/aem.00163-23\">10.1128/aem.00163-23</a>","bjps":"<b>Tribelhorn K <i>et al.</i></b> (2023) A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys Chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam. <i>Applied and Environmental Microbiology</i> <b>89</b>.","van":"Tribelhorn K, Twarużek M, Kosicki R, Straubinger RK, Ebel F, Ulrich S. A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam. Applied and Environmental Microbiology. 2023;89(7).","chicago":"Tribelhorn, Katharina, Magdalena Twarużek, Robert Kosicki, Reinhard K. Straubinger, Frank Ebel, and Sebastian Ulrich. “A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys Chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam.” <i>Applied and Environmental Microbiology</i> 89, no. 7 (2023). <a href=\"https://doi.org/10.1128/aem.00163-23\">https://doi.org/10.1128/aem.00163-23</a>.","ieee":"K. Tribelhorn, M. Twarużek, R. Kosicki, R. K. Straubinger, F. Ebel, and S. Ulrich, “A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam,” <i>Applied and Environmental Microbiology</i>, vol. 89, no. 7, 2023, doi: <a href=\"https://doi.org/10.1128/aem.00163-23\">10.1128/aem.00163-23</a>.","chicago-de":"Tribelhorn, Katharina, Magdalena Twarużek, Robert Kosicki, Reinhard K. Straubinger, Frank Ebel und Sebastian Ulrich. 2023. A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam. <i>Applied and Environmental Microbiology</i> 89, Nr. 7. doi:<a href=\"https://doi.org/10.1128/aem.00163-23\">10.1128/aem.00163-23</a>, .","short":"K. Tribelhorn, M. Twarużek, R. Kosicki, R.K. Straubinger, F. Ebel, S. Ulrich, Applied and Environmental Microbiology 89 (2023).","havard":"K. Tribelhorn, M. Twarużek, R. Kosicki, R.K. Straubinger, F. Ebel, S. Ulrich, A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam, Applied and Environmental Microbiology. 89 (2023).","din1505-2-1":"<span style=\"font-variant:small-caps;\">Tribelhorn, Katharina</span> ; <span style=\"font-variant:small-caps;\">Twarużek, Magdalena</span> ; <span style=\"font-variant:small-caps;\">Kosicki, Robert</span> ; <span style=\"font-variant:small-caps;\">Straubinger, Reinhard K.</span> ; <span style=\"font-variant:small-caps;\">Ebel, Frank</span> ; <span style=\"font-variant:small-caps;\">Ulrich, Sebastian</span>: A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam. In: <i>Applied and Environmental Microbiology</i> Bd. 89.   Washington, DC [u.a.], American Society for Microbiology (2023), Nr. 7","mla":"Tribelhorn, Katharina, et al. “A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys Chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam.” <i>Applied and Environmental Microbiology</i>, vol. 89, no. 7, 2023, <a href=\"https://doi.org/10.1128/aem.00163-23\">https://doi.org/10.1128/aem.00163-23</a>.","apa":"Tribelhorn, K., Twarużek, M., Kosicki, R., Straubinger, R. K., Ebel, F., &#38; Ulrich, S. (2023). A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam. <i>Applied and Environmental Microbiology</i>, <i>89</i>(7). <a href=\"https://doi.org/10.1128/aem.00163-23\">https://doi.org/10.1128/aem.00163-23</a>"},"status":"public","doi":"10.1128/aem.00163-23","place":"  Washington, DC [u.a.]","date_created":"2025-06-15T09:51:52Z","issue":"7","publisher":"American Society for Microbiology","_id":"12941","abstract":[{"lang":"eng","text":"Stachybotrys chartarum (Hypocreales, Ascomycota) is a toxigenic fungus that is frequently isolated from water-damaged buildings or improperly stored feed. The secondary metabolites formed by this mold have been associated with health problems in humans and animals. Several authors have studied the influence of environmental conditions on the production of mycotoxins, but these studies focused on undefined or complex substrates, such as building materials and media that impeded investigations of the influence of specific nutrients. In this study, a chemically defined cultivation medium was used to investigate the impact of several nitrogen and carbon sources on growth of S. chartarum and its production of macrocyclic trichothecenes (MTs) and stachybotrylactam (STLAC). Increasing concentrations of sodium nitrate were found to positively affect mycelial growth, the level of sporulation, and MT production, while ammonium nitrate and ammonium chloride had an inhibitory effect. Potato starch was the superior and most reliable carbon source tested. Additionally, we observed that the level of sporulation was correlated with the production of MTs but not with that of STLAC. In this study, we provide a chemically well-defined cultivation medium suitable for standardized in vitro testing of the capacity of S. chartarum isolates to produce macrocyclic trichothecenes."}],"department":[{"_id":"DEP4010"}],"type":"scientific_journal_article","quality_controlled":"1","publication_status":"published","author":[{"first_name":"Katharina","full_name":"Tribelhorn, Katharina","last_name":"Tribelhorn"},{"full_name":"Twarużek, Magdalena","last_name":"Twarużek","first_name":"Magdalena"},{"full_name":"Kosicki, Robert","last_name":"Kosicki","first_name":"Robert"},{"last_name":"Straubinger","full_name":"Straubinger, Reinhard K.","first_name":"Reinhard K."},{"first_name":"Frank","last_name":"Ebel","full_name":"Ebel, Frank"},{"orcid":"0000-0002-4511-9537","full_name":"Ulrich, Sebastian","id":"85847","last_name":"Ulrich","first_name":"Sebastian"}],"publication":"Applied and Environmental Microbiology","user_id":"83781","publication_identifier":{"eissn":["1098-5336"],"issn":["0099-2240"]},"language":[{"iso":"eng"}],"intvolume":"        89","volume":89,"year":"2023","date_updated":"2025-06-16T09:21:50Z","extern":"1","title":"A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam"}