168 Publikationen
2013 | Konferenz - Poster | ELSA-ID: 2982
Hahne, T., Schwarze, B., Moschinski, J., Kuttig, A., Kramer, M., & Frahm, B. (2013). Disposable Algenkultivierung für hochpreisige Produkte mittels LED-Rundumbeleuchtung direkt auf den Bags. Presented at the 6. Bundesalgenstammtisch, Hamburg, Germany.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, T., Pörtner, R., & Frahm, B. (2013). Seed train optimization for suspension cell culture. Presented at the 23rd Meeting of the European Society for Animal Cell Technology (ESACT): Better Cells for Better Health, Lille, France.
ELSA
2013 | Sammelwerk - Beitrag | ELSA-ID: 10214
Frahm, B. (2013). Seed Train Optimization for Cell Culture. In R. Pörtner (Ed.), Animal Cell Biotechnology - Methods and Protocols (3rd ed., Vol. 1104, pp. 355–367). Humana Press. https://doi.org/10.1007/978-1-62703-733-4_22
ELSA
| DOI
2012 | Konferenzband - Beitrag | ELSA-ID: 2816 |

Frahm, B., & Brod, H. (2012). Improving Cell Culture Bioreactor Performance for Sensitive Cell Lines by Dynamic Membrane Aeration (DMA). Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009 (Vol. 5, pp. 355–359). Dordrecht: Springer. https://doi.org/10.1007/978-94-007-0884-6_56
ELSA
| DOI
| Download (ext.)
2012 | Patent | ELSA-ID: 2877
Brod, H., & Frahm, B. (2012). Photobioreaktor mit rotatorisch oszillierenden Lichtquellen.
ELSA
2012 | Konferenz - Vortrag | ELSA-ID: 2918
Van Hecke, W., Haltrich, D., Frahm, B., Brod, H., & Ludwig, R. (2012). Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor. Achema 2012. Frankfurt am Main, Germany: Vogel Business Media.
ELSA
2012 | Konferenz - Poster | ELSA-ID: 2973
Marzougui, R., Pörtner, R., & Frahm, B. (2012). Optimierung des Seed trains von Suspensions-Zellkulturen. Presented at the GVC / DECHEMA Vortrags- und Diskussionstagung “Biopharmazeutische Produktion,” Freiburg, Germany.
ELSA
2011 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2350
Van Hecke, W., Haltrich, D., Frahm, B., Brod, H., Dewulf, J., Van Langenhove, H., & Ludwig, R. (2011). A biocatalytic cascade reaction sensitive to the gas–liquid interface: Modeling and upscaling in a dynamic membrane aeration reactor. Journal of Molecular Catalysis B: Enzymatic, 68(2), 154–161. https://doi.org/10.1016/j.molcatb.2010.10.004
ELSA
| DOI
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2011 | Patent | ELSA-ID: 2876
Brod, H., Frahm, B., Jenne, M., Kauling, J., Schmitt, F., & Seletzky, J. (2011). Flüssigkeitsbegaser.
ELSA
2011 | Konferenz - Poster | ELSA-ID: 2972
Van Hecke, W., Haltrich, D., Frahm, B., Brod, H., & Ludwig, R. (2011). Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor. Presented at the 1st European Congress of Applied Biotechnology together with DECHEMA’s Biotechnology Annual Meeting, Berlin, Germany.
ELSA
2010 | Konferenzband - Beitrag | ELSA-ID: 2815
Dercks, B., Frahm, B., Grünewald, M., Kenig, E., Lautenschleger, A., Gorak, A., … Zecirovic, R. (2010). Intensified absorption and distillation devices for modular chemical production processes. Proceedings 19th International Congress of Chemical and Process Engineering. Prague, CZ: Czech Society of Chemical Engineering.
ELSA
2010 | Patent | ELSA-ID: 2873
Brod, H., Frahm, B., & Kauling, J. (2010). Verfahren zur Reduzierung von Ablagerungen bei der Kultivierung von Organismen.
ELSA
2010 | Patent | ELSA-ID: 2874
Brod, H., Frahm, B., Jenne, M., & Kauling, J. (2010). Bioreaktor.
ELSA
2010 | Patent | ELSA-ID: 2875
Frahm, B., Kauling, J., Pütz, A., & Schindler, M. (2010). Begasungssystem.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2892
Frahm, B., & Brod, H. (2010). Cultivation of sensitive cell lines - Improving bioreactor performance by Dynamic Membrane Aeration. Presented at the 6th annual Optimizing Cell Culture Technology-Meeting as part of The Bioprocessing Summit - Practical Solutions for Today’s Laboratory Challenges, Boston, USA.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2913
Dercks, B., Frahm, B., Grünewald, M., Kenig, E., Lautenschleger, A., Gorak, A., … Zecirovic, R. (2010). Intensified absorption and distillation devices for modular chemical production processes. Presented at the 19th International Congress of Chemical and Process Engineering, CHISA , Prague, Czech Republic.
ELSA
2009 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2349 |

Frahm, B., Brod, H., & Langer, U. (2009). Improving bioreactor cultivation conditions for sensitive cell lines by dynamic membrane aeration. Cytotechnology, 59(1), 17–30. https://doi.org/10.1007/s10616-009-9189-9
ELSA
| DOI
| Download (ext.)
2009 | Patent | ELSA-ID: 2872
Braun, A., Brod, H., Frahm, B., Jenne, M., Kauling, J., & Kirchner, S. (2009). Verfahren und Vorrichtung zur Rückhaltung und Rückführung von Zellen.
ELSA
2009 | Konferenz - Vortrag | ELSA-ID: 2912
Frahm, B., Brod, H., & Langer, U. (2009). Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA). Presented at the Industrial Biotechnology Exhibition & Partnering Conference at ACHEMA , Frankfurt am Main, Germany.
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2970
Frahm, B., Brod, H., & Langer, U. (2009). Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA). Presented at the 21st Meeting of the European Society for Animal Cell Technology (ESACT): Cellular Solutions for Clinical Challenges, Dublin, Ireland.
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2971
Van Hecke, W., Van Langenhovve, H., Frahm, B., Brod, H., Dewulf, J., Haltrich, D., & Ludwig, R. (2009). Upscaling the biocatalytic conversion of lactose to lactobionic acid with the dynamic membrane aeration reactor. Presented at the COST 928 Control and exploitation of enzymes for added-value products, 3rd Annual Workshop, Krakow, Poland.
ELSA
2008 | Konferenz - Vortrag | ELSA-ID: 2911
Brod, H., Kauling, J., Frahm, B., Jenne, M., Langer, U., & Bödeker, B. (2008). Pushing the Limits in High-Density Mammalian Cell Fermentation. Presented at the Technology Colloquium, BayKomm, Leverkusen, Germany.
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2968
Frahm, B., Brod, H., Burnett, M., Langer, U., & Bödeker, B. (2008). High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA). Presented at the Bayer Science Day, Palladium, Cologne, Germany.
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2969
Frahm, B., & Brod, H. (2008). High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA). Presented at the Technology Colloquium, BayKomm, Leverkusen, Germany.
ELSA
2007 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2348
Frahm, B., Kirchner, S., Kauling, J., Brod, H., Langer, U., & Bödeker, B. (2007). Dynamische Membranbegasung im Bioreaktor zur Intensivierung der Sauerstoffversorgung empfindlicher Zelllinien. Chemie Ingenieur Technik, 79(7), 1052–1058. https://doi.org/10.1002/cite.200700070
ELSA
| DOI
| Download (ext.)
2007 | Konferenzband - Beitrag | ELSA-ID: 2814
Pörtner, R., Frahm, B., Lane, P., Munack, A., Kühn, K., & Hass, V. C. (2007). Optimisation of Time-space-yield for Hybridoma fed-batch Cultures with an Adaptive Olfo-controller. Cell Technology for Cell Products (Vol. 3, pp. 497–501). Dordrecht: Springer. https://doi.org/10.1007/978-1-4020-5476-1_84
ELSA
| DOI
2007 | Patent | ELSA-ID: 2870 |

Brod, H., Frahm, B., Kauling, J., & Rose, R. (2007). Procedure for gassing of liquid for cell cultures, comprises exchanging of gas over immersed membrane surfaces and controlling the gassing rate change of the gas concentration and/or pressure of the gas or gas mixture or gas component.
ELSA
| Download (ext.)
2007 | Patent | ELSA-ID: 2871
Brod, H., Frahm, B., Kauling, J., Poggel, M., Rose, R., & Schmidt, S. (2007). Verfahren und Vorrichtung zur Be- und Entgasung von Flüssigkeiten, insbesondere in der Biotechnologie und speziell von Zellkulturen.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2909
Brod, H., Frahm, B., & Kauling, J. (2007). Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen. Presented at the GVC Fachausschuss Mischvorgänge, Würzburg, Germany.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2910
Brod, H., Frahm, B., & Kauling, J. (2007). Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen. Presented at the GVC / DECHEMA Vortrags- und Diskussionstagung „Aufarbeitung biotechnologischer Produkte", Osnabrück, Germany.
ELSA
2007 | Konferenz - Poster | ELSA-ID: 2967
Frahm, B., Kirchner, S., Rose, R., Jenne, M., Kauling, J., Brod, H., … Bödeker, B. (2007). High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA). Presented at the Technology Colloquium, BayKomm, Leverkusen, Germany.
ELSA
2005 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2347 |

Frahm, B., Lane, P., Munack, A., & Pörtner, R. (2005). Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode. Chemie Ingenieur Technik, 77(4), 429–435. https://doi.org/10.1002/cite.200407094
ELSA
| DOI
| Download (ext.)
2005 | Konferenzband - Beitrag | ELSA-ID: 2813
Frahm, B., & Pörtner, R. (2005). Flexible Fed-Batch Process Control of Animal Cells. Animal Cell Technology Meets Genomics (Vol. 2, pp. 693–695). Dordrecht: Springer. https://doi.org/10.1007/1-4020-3103-3_142
ELSA
| DOI
2005 | Konferenz - Vortrag | ELSA-ID: 2907
Pörtner, R., Frahm, B., Lane, P., & Munack, A. (2005). Optimisation of time-space-yield for hybridoma fed-batch cultures with an adaptive OLFO-controller. Presented at the 19th Meeting of the European Society for Animal Cell Technology (ESACT): Cell Technology for Cell Products, Harrogate, UK.
ELSA
2005 | Konferenz - Vortrag | ELSA-ID: 2908
Pörtner, R., Frahm, B., Hass, V. C., Lane, P., & Munack, A. (2005). Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode. Presented at the GVC / DECHEMA-Jahrestagungen 2005, Wiesbaden, Germany.
ELSA
2004 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2345 |

Pörtner, R., Schwabe, J.-O., & Frahm, B. (2004). Evaluation of selected control strategies for fed-batch cultures of a hybridoma cell line. Biotechnology and Applied Biochemistry, 40. https://doi.org/10.1042/ba20030168
ELSA
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2003 | Konferenz - Vortrag | ELSA-ID: 7934
Frahm, B., & Pörtner, R. (2003). Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies. Presented at the 13th ESACT UK Meeting, Manchester, UK.
ELSA
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2343 |

Frahm, B., Hass, V. C., Lane, P., Munack, A., Märkl, H., & Pörtner, R. (2003). Fed-Batch-Kultivierung tierischer Zellen - Eine Herausforderung zur adaptiven, modellbasierten Steuerung. Chemie Ingenieur Technik, 75(4), 457–460. https://doi.org/10.1002/cite.200390093
ELSA
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| Download (ext.)
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2344 |

Frahm, B., Lane, P., Märkl, H., & Pörtner, R. (2003). Improvement of a mammalian cell culture process by adaptive, model-based dialysis fed-batch cultivation and suppression of apoptosis. Bioprocess and Biosystems Engineering, 26(1), 1–10. https://doi.org/10.1007/s00449-003-0335-z
ELSA
| DOI
| Download (ext.)
2003 | Dissertation | ELSA-ID: 2393
Frahm, B. (2003). Adaptive, modellgestützte Prozessführung von Suspensionskulturen tierischer Zellen. Norderstedt: Books on Demand GmbH.
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2435
Frahm, B., Müller-Landré, B., Wiggers de Almeida, G., Singer, M., Rausch, M., Lane, P., … Pörtner, R. (2003). Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control. (D. Beckmann & Heiligenstädter Kolloquium (11 : 2002 : Heiligenstadt, Eichsfeld), Eds.), Technische Systeme für Biotechnologie und Umwelt (pp. 503–509). Heiligenstadt: Inst. für Bioprozess- und Analysenmesstechnik .
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2436
Kühn, K., Frahm, B., Pörtner, R., Lane, P., Munack, A., & Hass, V. C. (2003). Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells. (European Federation of Chemical Engineering, Ed.), ECCE - 4th European Congress of Chemical Engineering (Vol. 10). Granada: ECCE4.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2902
Frahm, B., & Pörtner, R. (2003). Fed-Batch-Kultivierungen tierischer Zellen – eine Herausforderung an eine modellgestützte, adaptive Steuerung. Presented at the “Zellkultur-Tag”, Sartorius-College, Göttingen, Germany.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2903
Hass, V. C., Kühn, K., Frahm, B., Pörtner, R., Lane, P., & Munack, A. (2003). Ein strukturiertes Kompartiment-Modell zur Beschreibung der Kultivierung von Hybridomazellen als Teil einer adaptiven, modellgestützten Prozessführung. Presented at the 21. DECHEMA-Jahrestagung der Biotechnologen, München.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2905
Frahm, B., Lane, P., Munack, A., Hass, V. C., & Pörtner, R. (2003). Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies. Presented at the 27. ACHEMA 2003, Frankfurt am Main, Germany.
ELSA
| Dateien verfügbar
2003 | Konferenz - Vortrag | ELSA-ID: 2906
Pörtner, R., Frahm, B., Lane, P., Hass, V. C., Munack, A., & Märkl, H. (2003). Fed-Batch-Kultivierung tierischer Zellen – eine Herausforderung für eine adaptive, modellgestützte Steuerung. Presented at the GVC / DECHEMA Vortrags- und Diskussionstagung „Zellkulturen: Vom biologischen System zum Produktionsprozess“, Bad Dürkheim, Germany.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2964
Frahm, B., & Pörtner, R. (2003). CO2-off-gas measurement for animal cell culture processes. Presented at the 13th ESACT UK Meeting, Manchester, UK.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2965
Frahm, B., & Pörtner, R. (2003). Flexible fed-batch process control of animal cells. Presented at the 18th Meeting of the European Society for Animal Cell Technology (ESACT): Animal Cell Technology Meets Genomics, Granada, Spain.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2966
Kühn, K., Frahm, B., Pörtner, R., Lane, P., Munack, A., & Hass, V. C. (2003). Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells. Presented at the 4th European Congress on Chemical Engineering, Granada, Spain.
ELSA
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2340 |

Frahm, B., Blank, H.-C., Cornand, P., Oelßner, W., Guth, U., Lane, P., … Pörtner, R. (2002). Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement. Journal of Biotechnology, 99(2), 133–148. https://doi.org/10.1016/S0168-1656(02)00180-3
ELSA
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2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2341 |

Frahm, B., Lane, P., Atzert, H., Munack, A., Hoffmann, M., Hass, V. C., & Pörtner, R. (2002). Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Effective Fed-Batch Cultivation of Hybridoma Cells. Biotechnology Progress, 18(5), 1095–1103. https://doi.org/10.1021/bp020035y
ELSA
| DOI
| Download (ext.)
2002 | Zeitschriftenaufsatz | ELSA-ID: 2342
Frahm, B., & Pörtner, R. (2002). Reaktor-Abgasmessungen bei Zellkulturen. BIOforum, 4, 179–180.
ELSA
2002 | Konferenzband - Beitrag | ELSA-ID: 2431
Frahm, B., & Pörtner, R. (2002). Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen. (H. Kaden & Forum Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung Biotechnologischer Prozesse (2001 : Waldheim), Eds.), Biosystemtechnik: Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung biotechnologischer Prozesse (pp. 39–48). Meinsberg : Kurt-Schwabe-Inst. .
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2897
Frahm, B., & Pörtner, R. (2002). Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen. Presented at the DECHEMA Jahrestagung der Biotechnologen, Wiesbaden, Germany.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2898
Frahm, B., & Pörtner, R. (2002). Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells. Presented at the Seminar of the Lonza Biologics R&D Group, Lonza Biologics, Slough, UK.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2899
Frahm, B., & Pörtner, R. (2002). Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells. Presented at the Seminar at the University of Birmingham, Birmingham, UK.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2900
Frahm, B., Müller-Landré, B., Wiggers de Almeida, G., Singer, M., Rausch, M., Lane, P., … Pörtner, R. (2002). Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control. Presented at the 11. Heiligenstädter Kolloquium, Technische Systeme für Biotechnologie und Umwelt, Heilbad Heiligenstadt, Germany.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 7933
Frahm, B., & Pörtner, R. (2001). Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen. Presented at the Innovationsforum 2001 „Innovative Biosystemtechnik – Sensorik, Aktorik und Auswertung biotechnologischer Prozesse“, Waldheim, Germany.
ELSA
2001 | Konferenzband - Beitrag | ELSA-ID: 2427
Frahm, B., Atzert, H., Lane, P., Hoffmann, M., Hass, V. C., Munack, A., & Pörtner, R. (2001). Development of an Automated, Adaptive Model-Based Control for the Effective Cultivation of Hybridoma Cells. Animal Cell Technology: From Target to Market (Vol. 1, pp. 446–448). Dordrecht: Springer. https://doi.org/10.1007/978-94-010-0369-8_107
ELSA
| DOI
2001 | Konferenz - Poster | ELSA-ID: 2429
Hass, V. C., Lane, P., Hoffmann, M., Frahm, B., Schwabe, J.-O., Pörtner, R., & Munack, A. (2001). Model-Based Control of Hybridoma Cell Cultures. Presented at the 8th International Conference on Computer Applications in Biotechnology, Québec City, Québec, Canada.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2894
Hoffmann, M., Hass, V. C., Frahm, B., Schwabe, J.-O., Pörtner, R., Lane, P., & Munack, A. (2001). Untersuchung verschiedener mathematischer Modelle in Hinblick auf ihre Eignung für die adaptive Prozessführung von Hybridoma Zellkulturen. Presented at the 19. DECHEMA Jahrestagung der Biotechnologen, Leipzig, Germany.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2895
Frahm, B., & Pörtner, R. (2001). Arbeitsschwerpunkte TUHH, Bioprozess- und Bioverfahrenstechnik, Arbeitsgruppe Zellkulturtechnik. Presented at the Biotechnica, Hannover.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2960
Frahm, B., Atzert, H., Schwabe, J.-O., Lane, P., Munack, A., Hoffmann, M., … Pörtner, R. (2001). Adaptive modellgestützte Steuerung von Zellkulturprozessen. Presented at the 19. DECHEMA Jahrestagung der Biotechnologen, Leipzig, Germany.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2961
Lane, P., Frahm, B., Atzert, H., Schwabe, J.-O., Hoffmann, M., Hass, V. C., & Pörtner, R. (2001). Design of Feeding Strategies for Fed-Batch Cultures of Animal Cells by the Method of Inequalities. Presented at the 19. DECHEMA Jahrestagung der Biotechnologen, Leipzig, Germany.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2962
Frahm, B., Atzert, H., Lane, P., Hoffmann, M., Hass, V. C., Munack, A., & Pörtner, R. (2001). Development of an automated, model-based, adaptive control for the effective cultivation of hybridoma cells. Presented at the 17th Meeting of the European Society for Animal Cell Technology (ESACT): From Target to Market, Tylösand, Sweden.
ELSA
2001 | Konferenzband - Beitrag | ELSA-ID: 2963 |

Hass, V. C., Lane, P., Hoffmann, M., Frahm, B., Schwabe, J.-O., Pörtner, R., & Munack, A. (2001). Model-Based Control of Hybridoma Cell Cultures. (Published for the International Federation of Automatic Control by Pergamon , Ed.), Computer Applications in Biotechnology, 2001: Modelling, Monitoring and Control of Biotechnological Processes (Vol. 34, pp. 323–329). Oxford: ScienceDirect. https://doi.org/10.1016/S1474-6670(17)34240-4
ELSA
| DOI
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2000 | Konferenz - Vortrag | ELSA-ID: 2893
Anderelei, T., Frahm, B., & Büchs, J. (2000). Online-Bestimmung der Sauerstofftransferrate (OTR) und der Kohlendioxidtransferrate (CTR) in geschüttelten Bioreaktoren. Presented at the GVC-Fachausschusstagung Bioverfahrenstechnik, Bamberg, Germany.
ELSA
2000 | Konferenz - Poster | ELSA-ID: 2959
Hoffmann, M., Frahm, B., Schwabe, J.-O., Lane, P., Pörtner, R., Hass, V. C., & Munack, A. (2000). Modellgestützte Prozessführung für Hybridoma-Kulturen mit Hilfe des Open-Loop-Feedback-Optimal (OLFO)- Algorithmus. Presented at the 10. Heiligenstädter Kolloquium, Technische Systeme für Biotechnologie und Umwelt, Heilbad Heiligenstadt, Germany.
ELSA
168 Publikationen
2013 | Konferenz - Poster | ELSA-ID: 2982
Hahne, T., Schwarze, B., Moschinski, J., Kuttig, A., Kramer, M., & Frahm, B. (2013). Disposable Algenkultivierung für hochpreisige Produkte mittels LED-Rundumbeleuchtung direkt auf den Bags. Presented at the 6. Bundesalgenstammtisch, Hamburg, Germany.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, T., Pörtner, R., & Frahm, B. (2013). Seed train optimization for suspension cell culture. Presented at the 23rd Meeting of the European Society for Animal Cell Technology (ESACT): Better Cells for Better Health, Lille, France.
ELSA
2013 | Sammelwerk - Beitrag | ELSA-ID: 10214
Frahm, B. (2013). Seed Train Optimization for Cell Culture. In R. Pörtner (Ed.), Animal Cell Biotechnology - Methods and Protocols (3rd ed., Vol. 1104, pp. 355–367). Humana Press. https://doi.org/10.1007/978-1-62703-733-4_22
ELSA
| DOI
2012 | Konferenzband - Beitrag | ELSA-ID: 2816 |

Frahm, B., & Brod, H. (2012). Improving Cell Culture Bioreactor Performance for Sensitive Cell Lines by Dynamic Membrane Aeration (DMA). Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009 (Vol. 5, pp. 355–359). Dordrecht: Springer. https://doi.org/10.1007/978-94-007-0884-6_56
ELSA
| DOI
| Download (ext.)
2012 | Patent | ELSA-ID: 2877
Brod, H., & Frahm, B. (2012). Photobioreaktor mit rotatorisch oszillierenden Lichtquellen.
ELSA
2012 | Konferenz - Vortrag | ELSA-ID: 2918
Van Hecke, W., Haltrich, D., Frahm, B., Brod, H., & Ludwig, R. (2012). Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor. Achema 2012. Frankfurt am Main, Germany: Vogel Business Media.
ELSA
2012 | Konferenz - Poster | ELSA-ID: 2973
Marzougui, R., Pörtner, R., & Frahm, B. (2012). Optimierung des Seed trains von Suspensions-Zellkulturen. Presented at the GVC / DECHEMA Vortrags- und Diskussionstagung “Biopharmazeutische Produktion,” Freiburg, Germany.
ELSA
2011 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2350
Van Hecke, W., Haltrich, D., Frahm, B., Brod, H., Dewulf, J., Van Langenhove, H., & Ludwig, R. (2011). A biocatalytic cascade reaction sensitive to the gas–liquid interface: Modeling and upscaling in a dynamic membrane aeration reactor. Journal of Molecular Catalysis B: Enzymatic, 68(2), 154–161. https://doi.org/10.1016/j.molcatb.2010.10.004
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2011 | Patent | ELSA-ID: 2876
Brod, H., Frahm, B., Jenne, M., Kauling, J., Schmitt, F., & Seletzky, J. (2011). Flüssigkeitsbegaser.
ELSA
2011 | Konferenz - Poster | ELSA-ID: 2972
Van Hecke, W., Haltrich, D., Frahm, B., Brod, H., & Ludwig, R. (2011). Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor. Presented at the 1st European Congress of Applied Biotechnology together with DECHEMA’s Biotechnology Annual Meeting, Berlin, Germany.
ELSA
2010 | Konferenzband - Beitrag | ELSA-ID: 2815
Dercks, B., Frahm, B., Grünewald, M., Kenig, E., Lautenschleger, A., Gorak, A., … Zecirovic, R. (2010). Intensified absorption and distillation devices for modular chemical production processes. Proceedings 19th International Congress of Chemical and Process Engineering. Prague, CZ: Czech Society of Chemical Engineering.
ELSA
2010 | Patent | ELSA-ID: 2873
Brod, H., Frahm, B., & Kauling, J. (2010). Verfahren zur Reduzierung von Ablagerungen bei der Kultivierung von Organismen.
ELSA
2010 | Patent | ELSA-ID: 2874
Brod, H., Frahm, B., Jenne, M., & Kauling, J. (2010). Bioreaktor.
ELSA
2010 | Patent | ELSA-ID: 2875
Frahm, B., Kauling, J., Pütz, A., & Schindler, M. (2010). Begasungssystem.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2892
Frahm, B., & Brod, H. (2010). Cultivation of sensitive cell lines - Improving bioreactor performance by Dynamic Membrane Aeration. Presented at the 6th annual Optimizing Cell Culture Technology-Meeting as part of The Bioprocessing Summit - Practical Solutions for Today’s Laboratory Challenges, Boston, USA.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2913
Dercks, B., Frahm, B., Grünewald, M., Kenig, E., Lautenschleger, A., Gorak, A., … Zecirovic, R. (2010). Intensified absorption and distillation devices for modular chemical production processes. Presented at the 19th International Congress of Chemical and Process Engineering, CHISA , Prague, Czech Republic.
ELSA
2009 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2349 |

Frahm, B., Brod, H., & Langer, U. (2009). Improving bioreactor cultivation conditions for sensitive cell lines by dynamic membrane aeration. Cytotechnology, 59(1), 17–30. https://doi.org/10.1007/s10616-009-9189-9
ELSA
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2009 | Patent | ELSA-ID: 2872
Braun, A., Brod, H., Frahm, B., Jenne, M., Kauling, J., & Kirchner, S. (2009). Verfahren und Vorrichtung zur Rückhaltung und Rückführung von Zellen.
ELSA
2009 | Konferenz - Vortrag | ELSA-ID: 2912
Frahm, B., Brod, H., & Langer, U. (2009). Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA). Presented at the Industrial Biotechnology Exhibition & Partnering Conference at ACHEMA , Frankfurt am Main, Germany.
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2970
Frahm, B., Brod, H., & Langer, U. (2009). Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA). Presented at the 21st Meeting of the European Society for Animal Cell Technology (ESACT): Cellular Solutions for Clinical Challenges, Dublin, Ireland.
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2971
Van Hecke, W., Van Langenhovve, H., Frahm, B., Brod, H., Dewulf, J., Haltrich, D., & Ludwig, R. (2009). Upscaling the biocatalytic conversion of lactose to lactobionic acid with the dynamic membrane aeration reactor. Presented at the COST 928 Control and exploitation of enzymes for added-value products, 3rd Annual Workshop, Krakow, Poland.
ELSA
2008 | Konferenz - Vortrag | ELSA-ID: 2911
Brod, H., Kauling, J., Frahm, B., Jenne, M., Langer, U., & Bödeker, B. (2008). Pushing the Limits in High-Density Mammalian Cell Fermentation. Presented at the Technology Colloquium, BayKomm, Leverkusen, Germany.
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2968
Frahm, B., Brod, H., Burnett, M., Langer, U., & Bödeker, B. (2008). High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA). Presented at the Bayer Science Day, Palladium, Cologne, Germany.
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2969
Frahm, B., & Brod, H. (2008). High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA). Presented at the Technology Colloquium, BayKomm, Leverkusen, Germany.
ELSA
2007 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2348
Frahm, B., Kirchner, S., Kauling, J., Brod, H., Langer, U., & Bödeker, B. (2007). Dynamische Membranbegasung im Bioreaktor zur Intensivierung der Sauerstoffversorgung empfindlicher Zelllinien. Chemie Ingenieur Technik, 79(7), 1052–1058. https://doi.org/10.1002/cite.200700070
ELSA
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2007 | Konferenzband - Beitrag | ELSA-ID: 2814
Pörtner, R., Frahm, B., Lane, P., Munack, A., Kühn, K., & Hass, V. C. (2007). Optimisation of Time-space-yield for Hybridoma fed-batch Cultures with an Adaptive Olfo-controller. Cell Technology for Cell Products (Vol. 3, pp. 497–501). Dordrecht: Springer. https://doi.org/10.1007/978-1-4020-5476-1_84
ELSA
| DOI
2007 | Patent | ELSA-ID: 2870 |

Brod, H., Frahm, B., Kauling, J., & Rose, R. (2007). Procedure for gassing of liquid for cell cultures, comprises exchanging of gas over immersed membrane surfaces and controlling the gassing rate change of the gas concentration and/or pressure of the gas or gas mixture or gas component.
ELSA
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2007 | Patent | ELSA-ID: 2871
Brod, H., Frahm, B., Kauling, J., Poggel, M., Rose, R., & Schmidt, S. (2007). Verfahren und Vorrichtung zur Be- und Entgasung von Flüssigkeiten, insbesondere in der Biotechnologie und speziell von Zellkulturen.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2909
Brod, H., Frahm, B., & Kauling, J. (2007). Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen. Presented at the GVC Fachausschuss Mischvorgänge, Würzburg, Germany.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2910
Brod, H., Frahm, B., & Kauling, J. (2007). Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen. Presented at the GVC / DECHEMA Vortrags- und Diskussionstagung „Aufarbeitung biotechnologischer Produkte", Osnabrück, Germany.
ELSA
2007 | Konferenz - Poster | ELSA-ID: 2967
Frahm, B., Kirchner, S., Rose, R., Jenne, M., Kauling, J., Brod, H., … Bödeker, B. (2007). High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA). Presented at the Technology Colloquium, BayKomm, Leverkusen, Germany.
ELSA
2005 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2347 |

Frahm, B., Lane, P., Munack, A., & Pörtner, R. (2005). Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode. Chemie Ingenieur Technik, 77(4), 429–435. https://doi.org/10.1002/cite.200407094
ELSA
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2005 | Konferenzband - Beitrag | ELSA-ID: 2813
Frahm, B., & Pörtner, R. (2005). Flexible Fed-Batch Process Control of Animal Cells. Animal Cell Technology Meets Genomics (Vol. 2, pp. 693–695). Dordrecht: Springer. https://doi.org/10.1007/1-4020-3103-3_142
ELSA
| DOI
2005 | Konferenz - Vortrag | ELSA-ID: 2907
Pörtner, R., Frahm, B., Lane, P., & Munack, A. (2005). Optimisation of time-space-yield for hybridoma fed-batch cultures with an adaptive OLFO-controller. Presented at the 19th Meeting of the European Society for Animal Cell Technology (ESACT): Cell Technology for Cell Products, Harrogate, UK.
ELSA
2005 | Konferenz - Vortrag | ELSA-ID: 2908
Pörtner, R., Frahm, B., Hass, V. C., Lane, P., & Munack, A. (2005). Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode. Presented at the GVC / DECHEMA-Jahrestagungen 2005, Wiesbaden, Germany.
ELSA
2004 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2345 |

Pörtner, R., Schwabe, J.-O., & Frahm, B. (2004). Evaluation of selected control strategies for fed-batch cultures of a hybridoma cell line. Biotechnology and Applied Biochemistry, 40. https://doi.org/10.1042/ba20030168
ELSA
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2003 | Konferenz - Vortrag | ELSA-ID: 7934
Frahm, B., & Pörtner, R. (2003). Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies. Presented at the 13th ESACT UK Meeting, Manchester, UK.
ELSA
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2343 |

Frahm, B., Hass, V. C., Lane, P., Munack, A., Märkl, H., & Pörtner, R. (2003). Fed-Batch-Kultivierung tierischer Zellen - Eine Herausforderung zur adaptiven, modellbasierten Steuerung. Chemie Ingenieur Technik, 75(4), 457–460. https://doi.org/10.1002/cite.200390093
ELSA
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2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2344 |

Frahm, B., Lane, P., Märkl, H., & Pörtner, R. (2003). Improvement of a mammalian cell culture process by adaptive, model-based dialysis fed-batch cultivation and suppression of apoptosis. Bioprocess and Biosystems Engineering, 26(1), 1–10. https://doi.org/10.1007/s00449-003-0335-z
ELSA
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2003 | Dissertation | ELSA-ID: 2393
Frahm, B. (2003). Adaptive, modellgestützte Prozessführung von Suspensionskulturen tierischer Zellen. Norderstedt: Books on Demand GmbH.
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2435
Frahm, B., Müller-Landré, B., Wiggers de Almeida, G., Singer, M., Rausch, M., Lane, P., … Pörtner, R. (2003). Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control. (D. Beckmann & Heiligenstädter Kolloquium (11 : 2002 : Heiligenstadt, Eichsfeld), Eds.), Technische Systeme für Biotechnologie und Umwelt (pp. 503–509). Heiligenstadt: Inst. für Bioprozess- und Analysenmesstechnik .
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2436
Kühn, K., Frahm, B., Pörtner, R., Lane, P., Munack, A., & Hass, V. C. (2003). Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells. (European Federation of Chemical Engineering, Ed.), ECCE - 4th European Congress of Chemical Engineering (Vol. 10). Granada: ECCE4.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2902
Frahm, B., & Pörtner, R. (2003). Fed-Batch-Kultivierungen tierischer Zellen – eine Herausforderung an eine modellgestützte, adaptive Steuerung. Presented at the “Zellkultur-Tag”, Sartorius-College, Göttingen, Germany.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2903
Hass, V. C., Kühn, K., Frahm, B., Pörtner, R., Lane, P., & Munack, A. (2003). Ein strukturiertes Kompartiment-Modell zur Beschreibung der Kultivierung von Hybridomazellen als Teil einer adaptiven, modellgestützten Prozessführung. Presented at the 21. DECHEMA-Jahrestagung der Biotechnologen, München.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2905
Frahm, B., Lane, P., Munack, A., Hass, V. C., & Pörtner, R. (2003). Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies. Presented at the 27. ACHEMA 2003, Frankfurt am Main, Germany.
ELSA
| Dateien verfügbar
2003 | Konferenz - Vortrag | ELSA-ID: 2906
Pörtner, R., Frahm, B., Lane, P., Hass, V. C., Munack, A., & Märkl, H. (2003). Fed-Batch-Kultivierung tierischer Zellen – eine Herausforderung für eine adaptive, modellgestützte Steuerung. Presented at the GVC / DECHEMA Vortrags- und Diskussionstagung „Zellkulturen: Vom biologischen System zum Produktionsprozess“, Bad Dürkheim, Germany.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2964
Frahm, B., & Pörtner, R. (2003). CO2-off-gas measurement for animal cell culture processes. Presented at the 13th ESACT UK Meeting, Manchester, UK.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2965
Frahm, B., & Pörtner, R. (2003). Flexible fed-batch process control of animal cells. Presented at the 18th Meeting of the European Society for Animal Cell Technology (ESACT): Animal Cell Technology Meets Genomics, Granada, Spain.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2966
Kühn, K., Frahm, B., Pörtner, R., Lane, P., Munack, A., & Hass, V. C. (2003). Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells. Presented at the 4th European Congress on Chemical Engineering, Granada, Spain.
ELSA
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2340 |

Frahm, B., Blank, H.-C., Cornand, P., Oelßner, W., Guth, U., Lane, P., … Pörtner, R. (2002). Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement. Journal of Biotechnology, 99(2), 133–148. https://doi.org/10.1016/S0168-1656(02)00180-3
ELSA
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2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2341 |

Frahm, B., Lane, P., Atzert, H., Munack, A., Hoffmann, M., Hass, V. C., & Pörtner, R. (2002). Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Effective Fed-Batch Cultivation of Hybridoma Cells. Biotechnology Progress, 18(5), 1095–1103. https://doi.org/10.1021/bp020035y
ELSA
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2002 | Zeitschriftenaufsatz | ELSA-ID: 2342
Frahm, B., & Pörtner, R. (2002). Reaktor-Abgasmessungen bei Zellkulturen. BIOforum, 4, 179–180.
ELSA
2002 | Konferenzband - Beitrag | ELSA-ID: 2431
Frahm, B., & Pörtner, R. (2002). Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen. (H. Kaden & Forum Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung Biotechnologischer Prozesse (2001 : Waldheim), Eds.), Biosystemtechnik: Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung biotechnologischer Prozesse (pp. 39–48). Meinsberg : Kurt-Schwabe-Inst. .
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2897
Frahm, B., & Pörtner, R. (2002). Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen. Presented at the DECHEMA Jahrestagung der Biotechnologen, Wiesbaden, Germany.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2898
Frahm, B., & Pörtner, R. (2002). Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells. Presented at the Seminar of the Lonza Biologics R&D Group, Lonza Biologics, Slough, UK.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2899
Frahm, B., & Pörtner, R. (2002). Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells. Presented at the Seminar at the University of Birmingham, Birmingham, UK.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2900
Frahm, B., Müller-Landré, B., Wiggers de Almeida, G., Singer, M., Rausch, M., Lane, P., … Pörtner, R. (2002). Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control. Presented at the 11. Heiligenstädter Kolloquium, Technische Systeme für Biotechnologie und Umwelt, Heilbad Heiligenstadt, Germany.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 7933
Frahm, B., & Pörtner, R. (2001). Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen. Presented at the Innovationsforum 2001 „Innovative Biosystemtechnik – Sensorik, Aktorik und Auswertung biotechnologischer Prozesse“, Waldheim, Germany.
ELSA
2001 | Konferenzband - Beitrag | ELSA-ID: 2427
Frahm, B., Atzert, H., Lane, P., Hoffmann, M., Hass, V. C., Munack, A., & Pörtner, R. (2001). Development of an Automated, Adaptive Model-Based Control for the Effective Cultivation of Hybridoma Cells. Animal Cell Technology: From Target to Market (Vol. 1, pp. 446–448). Dordrecht: Springer. https://doi.org/10.1007/978-94-010-0369-8_107
ELSA
| DOI
2001 | Konferenz - Poster | ELSA-ID: 2429
Hass, V. C., Lane, P., Hoffmann, M., Frahm, B., Schwabe, J.-O., Pörtner, R., & Munack, A. (2001). Model-Based Control of Hybridoma Cell Cultures. Presented at the 8th International Conference on Computer Applications in Biotechnology, Québec City, Québec, Canada.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2894
Hoffmann, M., Hass, V. C., Frahm, B., Schwabe, J.-O., Pörtner, R., Lane, P., & Munack, A. (2001). Untersuchung verschiedener mathematischer Modelle in Hinblick auf ihre Eignung für die adaptive Prozessführung von Hybridoma Zellkulturen. Presented at the 19. DECHEMA Jahrestagung der Biotechnologen, Leipzig, Germany.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2895
Frahm, B., & Pörtner, R. (2001). Arbeitsschwerpunkte TUHH, Bioprozess- und Bioverfahrenstechnik, Arbeitsgruppe Zellkulturtechnik. Presented at the Biotechnica, Hannover.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2960
Frahm, B., Atzert, H., Schwabe, J.-O., Lane, P., Munack, A., Hoffmann, M., … Pörtner, R. (2001). Adaptive modellgestützte Steuerung von Zellkulturprozessen. Presented at the 19. DECHEMA Jahrestagung der Biotechnologen, Leipzig, Germany.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2961
Lane, P., Frahm, B., Atzert, H., Schwabe, J.-O., Hoffmann, M., Hass, V. C., & Pörtner, R. (2001). Design of Feeding Strategies for Fed-Batch Cultures of Animal Cells by the Method of Inequalities. Presented at the 19. DECHEMA Jahrestagung der Biotechnologen, Leipzig, Germany.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2962
Frahm, B., Atzert, H., Lane, P., Hoffmann, M., Hass, V. C., Munack, A., & Pörtner, R. (2001). Development of an automated, model-based, adaptive control for the effective cultivation of hybridoma cells. Presented at the 17th Meeting of the European Society for Animal Cell Technology (ESACT): From Target to Market, Tylösand, Sweden.
ELSA
2001 | Konferenzband - Beitrag | ELSA-ID: 2963 |

Hass, V. C., Lane, P., Hoffmann, M., Frahm, B., Schwabe, J.-O., Pörtner, R., & Munack, A. (2001). Model-Based Control of Hybridoma Cell Cultures. (Published for the International Federation of Automatic Control by Pergamon , Ed.), Computer Applications in Biotechnology, 2001: Modelling, Monitoring and Control of Biotechnological Processes (Vol. 34, pp. 323–329). Oxford: ScienceDirect. https://doi.org/10.1016/S1474-6670(17)34240-4
ELSA
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2000 | Konferenz - Vortrag | ELSA-ID: 2893
Anderelei, T., Frahm, B., & Büchs, J. (2000). Online-Bestimmung der Sauerstofftransferrate (OTR) und der Kohlendioxidtransferrate (CTR) in geschüttelten Bioreaktoren. Presented at the GVC-Fachausschusstagung Bioverfahrenstechnik, Bamberg, Germany.
ELSA
2000 | Konferenz - Poster | ELSA-ID: 2959
Hoffmann, M., Frahm, B., Schwabe, J.-O., Lane, P., Pörtner, R., Hass, V. C., & Munack, A. (2000). Modellgestützte Prozessführung für Hybridoma-Kulturen mit Hilfe des Open-Loop-Feedback-Optimal (OLFO)- Algorithmus. Presented at the 10. Heiligenstädter Kolloquium, Technische Systeme für Biotechnologie und Umwelt, Heilbad Heiligenstadt, Germany.
ELSA