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140 Publikationen
2022 | Konferenz - Poster | ELSA-ID: 7932
A systematic, model-based workflow for risk-based decision making in upstream development
T. Hernández Rodriguez, S. Ramm, M. Lange-Hegermann, B. Frahm, A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development, n.d.
ELSA
T. Hernández Rodriguez, S. Ramm, M. Lange-Hegermann, B. Frahm, A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development, n.d.
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Model-assisted DoE applied to microalgae processes, Current Research in Biotechnology
V. Gassenmeier, S. Deppe, T. Hernández Rodriguez, F. Kuhfuß, A. Moser, V.C. Hass, K.B. Kuchemüller, R. Pörtner, J. Möller, G.A. Ifrim, B. Frahm, Current Research in Biotechnology 4 (2022) 102–119.
ELSA
| DOI
V. Gassenmeier, S. Deppe, T. Hernández Rodriguez, F. Kuhfuß, A. Moser, V.C. Hass, K.B. Kuchemüller, R. Pörtner, J. Möller, G.A. Ifrim, B. Frahm, Current Research in Biotechnology 4 (2022) 102–119.
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
View on a mechanistic model of Chlorella vulgaris in incubated shake flasks
F. Kuhfuß, V. Gassenmeier, S. Deppe, G.A. Ifrim, T. Hernández Rodriguez, B. Frahm, Bioprocess and Biosystems Engineering 45 (2022) 15–30.
ELSA
| DOI
F. Kuhfuß, V. Gassenmeier, S. Deppe, G.A. Ifrim, T. Hernández Rodriguez, B. Frahm, Bioprocess and Biosystems Engineering 45 (2022) 15–30.
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Digital Seed Train Twins and Statistical Methods
T. Hernández Rodriguez, B. Frahm, in: C. Herwig, R. Pörtner, J. Möller (Eds.), Digital Twins Tools and Concepts for Smart Biomanufacturing, Springer, Berlin, Heidelberg, 2021, pp. 97–131.
ELSA
| DOI
T. Hernández Rodriguez, B. Frahm, in: C. Herwig, R. Pörtner, J. Möller (Eds.), Digital Twins Tools and Concepts for Smart Biomanufacturing, Springer, Berlin, Heidelberg, 2021, pp. 97–131.
2021 | Konferenz - Vortrag | ELSA-ID: 7927
Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction
T. Hernández Rodriguez, B. Frahm, Model-Based Methods in Bioprocess Technology - Bioprocess Modeling, Simulation and Prediction, 2021.
ELSA
T. Hernández Rodriguez, B. Frahm, Model-Based Methods in Bioprocess Technology - Bioprocess Modeling, Simulation and Prediction, 2021.
2021 | Konferenz - Poster | ELSA-ID: 7931
Model-assisted Design of Experiments - Concept, Software and Applications
A. Moser, J. Möller, K.B. Kuchemüller, S. Deppe, T. Hernández Rodriguez, V. Gassenmeier, G.A. Ifrim, B. Frahm, R. Pörtner, V.C. Hass, Model-Assisted Design of Experiments - Concept, Software and Applications, 2021.
ELSA
A. Moser, J. Möller, K.B. Kuchemüller, S. Deppe, T. Hernández Rodriguez, V. Gassenmeier, G.A. Ifrim, B. Frahm, R. Pörtner, V.C. Hass, Model-Assisted Design of Experiments - Concept, Software and Applications, 2021.
2021 | Lexikoneintrag | ELSA-ID: 7939
Bovine Colostrum for Human Consumption
G. Wirtanen, J. Alarinta, B. Frahm, S. Fasse, in: MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science, 2021.
ELSA
G. Wirtanen, J. Alarinta, B. Frahm, S. Fasse, in: MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science, 2021.
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7981
Bovine Colostrum for Human Consumption - Improving Microbial Quality and Maintaining Bioactive Characteristics through Processing
S. Fasse, J. Alarinta, B. Frahm, G. Wirtanen, Dairy 2 (2021) 556–575.
ELSA
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| WoS
S. Fasse, J. Alarinta, B. Frahm, G. Wirtanen, Dairy 2 (2021) 556–575.
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study
T. Hernández Rodriguez, S. Morerod, R. Pörtner, F.M. Wurm, B. Frahm, in: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, MDPI, Basel, 2021, pp. 49–74.
ELSA
| DOI
T. Hernández Rodriguez, S. Morerod, R. Pörtner, F.M. Wurm, B. Frahm, in: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, MDPI, Basel, 2021, pp. 49–74.
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train
T. Hernández Rodriguez, C. Posch, R. Pörtner, B. Frahm, Bioprocess and Biosystems Engineering 44 (2021) 793–808.
ELSA
| DOI
T. Hernández Rodriguez, C. Posch, R. Pörtner, B. Frahm, Bioprocess and Biosystems Engineering 44 (2021) 793–808.
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Model-assisted DoE software: Optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses
A. Moser, K.B. Kuchemüller, S. Deppe, T. Hernández Rodriguez, B. Frahm, R. Pörtner, V.C. Hass, J. Möller, Bioprocess and Biosystems Engineering 44 (2021) 683–700.
ELSA
| DOI
A. Moser, K.B. Kuchemüller, S. Deppe, T. Hernández Rodriguez, B. Frahm, R. Pörtner, V.C. Hass, J. Möller, Bioprocess and Biosystems Engineering 44 (2021) 683–700.
2021 | Konferenz - Vortrag | ELSA-ID: 8078
Messtechnikkonzepte für die Erfassung von qualitätsrelevanten Parametern und Merkmalen bei der Weizenteigverarbeitung
A. Blome, M. Luttmann, B. Frahm, U. Müller, Messtechnikkonzepte Für Die Erfassung von Qualitätsrelevanten Parametern Und Merkmalen Bei Der Weizenteigverarbeitung, 2021.
ELSA
A. Blome, M. Luttmann, B. Frahm, U. Müller, Messtechnikkonzepte Für Die Erfassung von Qualitätsrelevanten Parametern Und Merkmalen Bei Der Weizenteigverarbeitung, 2021.
2020 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2392
Model uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processes
J. Möller, T. Hernández Rodríguez, J. Müller, L. Arndt, K.B. Kuchemüller, B. Frahm, R. Eibl, D. Eibl, R. Pörtner, Computers & Chemical Engineering 134 (2020) 1–13.
ELSA
| DOI
J. Möller, T. Hernández Rodríguez, J. Müller, L. Arndt, K.B. Kuchemüller, B. Frahm, R. Eibl, D. Eibl, R. Pörtner, Computers & Chemical Engineering 134 (2020) 1–13.
2020 | Sammelwerk - Beitrag | ELSA-ID: 2397
Design, Optimization and Adaptive Control of Cell Culture Seed Trains
T. Hernández Rodríguez, B. Frahm, in: R. Pörtner (Ed.), Animal Cell Biotechnology - Methods and Protocols, Springer, Berlin, Heidelberg, New York, 2020, pp. 251–267.
ELSA
| DOI
T. Hernández Rodríguez, B. Frahm, in: R. Pörtner (Ed.), Animal Cell Biotechnology - Methods and Protocols, Springer, Berlin, Heidelberg, New York, 2020, pp. 251–267.
2020 | Sammelwerk - Beitrag | ELSA-ID: 2399
Estimation of Process Model Parameters
S. Deppe, B. Frahm, V.C. Hass, T. Hernández Rodríguez, K.B. Kuchemüller, J. Möller, R. Pörtner, in: R. Pörtner (Ed.), Animal Cell Biotechnology: Methods and Protocols, Springer, Berlin ; Heidelberg ; New York, 2020, pp. 213–234.
ELSA
| DOI
S. Deppe, B. Frahm, V.C. Hass, T. Hernández Rodríguez, K.B. Kuchemüller, J. Möller, R. Pörtner, in: R. Pörtner (Ed.), Animal Cell Biotechnology: Methods and Protocols, Springer, Berlin ; Heidelberg ; New York, 2020, pp. 213–234.
2020 | Konferenz - Poster | ELSA-ID: 7929
Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration
T. Hernández Rodriguez, S. Deppe, V. Gassenmeier, F. Kuhfuß, M. Tölle, G.A. Ifrim, B. Frahm, Modeling of Chlorella Vulgaris in Shake Flasks with Respect to Light Intensity and Light Duration, 2020.
ELSA
T. Hernández Rodriguez, S. Deppe, V. Gassenmeier, F. Kuhfuß, M. Tölle, G.A. Ifrim, B. Frahm, Modeling of Chlorella Vulgaris in Shake Flasks with Respect to Light Intensity and Light Duration, 2020.
2020 | Konferenz - Poster | ELSA-ID: 7930
Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes
T. Hernández Rodriguez, C. Posch, R. Pörtner, B. Frahm, Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes, 2020.
ELSA
T. Hernández Rodriguez, C. Posch, R. Pörtner, B. Frahm, Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes, 2020.
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Integration of prior knowledge and digital tools for uncertainty-based decision support
T. Hernández Rodriguez, B. Frahm, C. Posch, Integration of Prior Knowledge and Digital Tools for Uncertainty-Based Decision Support, 2020.
ELSA
T. Hernández Rodriguez, B. Frahm, C. Posch, Integration of Prior Knowledge and Digital Tools for Uncertainty-Based Decision Support, 2020.
2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Modeling of Chlorella vulgaris algae in shake flasks with respect to light intensity and light duration
T. Hernández Rodriguez, S. Deppe, V. Gassenmeier, F. Kuhfuß, M. Tölle, G.A. Ifrim, B. Frahm, Modeling of Chlorella Vulgaris Algae in Shake Flasks with Respect to Light Intensity and Light Duration, Wiley, 2020.
ELSA
| DOI
T. Hernández Rodriguez, S. Deppe, V. Gassenmeier, F. Kuhfuß, M. Tölle, G.A. Ifrim, B. Frahm, Modeling of Chlorella Vulgaris Algae in Shake Flasks with Respect to Light Intensity and Light Duration, Wiley, 2020.
2020 | Konferenzband - Beitrag | ELSA-ID: 7938
Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes
T. Hernández Rodriguez, C. Posch, R. Pörtner, B. Frahm, Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes, Wiley, 2020.
ELSA
| DOI
T. Hernández Rodriguez, C. Posch, R. Pörtner, B. Frahm, Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes, Wiley, 2020.