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336 Publikationen


2022 | Konferenz - Poster | ELSA-ID: 7932
A systematic, model-based workflow for risk-based decision making in upstream development
T. Hernández Rodriguez, S. Ramm, M. Lange-Hegermann, B. Frahm, A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development, 2022.
ELSA
 

2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7975
Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design
T. Hernández Rodriguez, A. Sekulic, M. Lange-Hegermann, B. Frahm, Processes, Special Issue: “Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing” 10 (2022).
ELSA | DOI
 

2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Model-assisted DoE applied to microalgae processes, Current Research in Biotechnology
V. Gassenmeier, S. Deppe, T. Hernández Rodriguez, F. Kuhfuß, A. Moser, V.C. Hass, K.B. Kuchemüller, R. Pörtner, J. Möller, G.A. Ifrim, B. Frahm, Current Research in Biotechnology 4 (2022) 102–119.
ELSA | DOI
 

2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
View on a mechanistic model of Chlorella vulgaris in incubated shake flasks
F. Kuhfuß, V. Gassenmeier, S. Deppe, G.A. Ifrim, T. Hernández Rodriguez, B. Frahm, Bioprocess and Biosystems Engineering 45 (2022) 15–30.
ELSA | DOI
 

2021 | Konferenz - Poster | ELSA-ID: 7931
Model-assisted Design of Experiments - Concept, Software and Applications
A. Moser, J. Möller, K.B. Kuchemüller, S. Deppe, T. Hernández Rodriguez, V. Gassenmeier, G.A. Ifrim, B. Frahm, R. Pörtner, V.C. Hass, Model-Assisted Design of Experiments - Concept, Software and Applications, 2021.
ELSA
 

2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7981 ELSA | DOI
 

2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Model-assisted DoE software: Optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses
A. Moser, K.B. Kuchemüller, S. Deppe, T. Hernández Rodriguez, B. Frahm, R. Pörtner, V.C. Hass, J. Möller, Bioprocess and Biosystems Engineering 44 (2021) 683–700.
ELSA | DOI
 

2021 | Konferenz - Vortrag | ELSA-ID: 8078
Messtechnikkonzepte für die Erfassung von qualitätsrelevanten Parametern und Merkmalen bei der Weizenteigverarbeitung
A. Blome, M. Luttmann, B. Frahm, U. Müller, Messtechnikkonzepte Für Die Erfassung von Qualitätsrelevanten Parametern Und Merkmalen Bei Der Weizenteigverarbeitung, 2021.
ELSA
 

2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7983
Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study
T. Hernández Rodriguez, S. Morerod, R. Pörtner, F.M. Wurm, B. Frahm, Processes, Special Issue: “Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing” 9 (2021).
ELSA | DOI
 

2021 | Konferenz - Vortrag | ELSA-ID: 7927
Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction
T. Hernández Rodriguez, B. Frahm, Model-Based Methods in Bioprocess Technology - Bioprocess Modeling, Simulation and Prediction, 2021.
ELSA
 

2021 | Lexikoneintrag | ELSA-ID: 7939
Bovine Colostrum for Human Consumption
G. Wirtanen, J. Alarinta, B. Frahm, S. Fasse, in: MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science, 2021.
ELSA
 

2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Digital Seed Train Twins and Statistical Methods
T. Hernández Rodriguez, B. Frahm, in: Advances in Biochemical Engineering/Biotechnology, Springer, Berlin, Heidelberg, 2021, p. 35.
ELSA | DOI
 

2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train
T. Hernández Rodriguez, C. Posch, R. Pörtner, B. Frahm, Bioprocess and Biosystems Engineering 44 (2021) 793–808.
ELSA | DOI
 

2020 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2392
Model uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processes
J. Möller, T. Hernández Rodríguez, J. Müller, L. Arndt, K.B. Kuchemüller, B. Frahm, R. Eibl, D. Eibl, R. Pörtner, Computers & Chemical Engineering 134 (2020) 1–13.
ELSA | DOI
 

2020 | Sammelwerk - Beitrag | ELSA-ID: 2397
Design, Optimization and Adaptive Control of Cell Culture Seed Trains
T. Hernández Rodríguez, B. Frahm, in: R. Pörtner (Ed.), Animal Cell Biotechnology - Methods and Protocols, Springer, Berlin, Heidelberg, New York, 2020, pp. 251–267.
ELSA | DOI
 

2020 | Konferenz - Poster | ELSA-ID: 3009
Modeling of microalgae in an air-lift photobioreactor for biomass production
G.A. Ifrim, S. Deppe, T. Hernández Rodriguez, V. Gassenmeier, B. Frahm, Modeling of Microalgae in an Air-Lift Photobioreactor for Biomass Production, 2020.
ELSA
 

2020 | Konferenz - Poster | ELSA-ID: 7929
Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration
T. Hernández Rodriguez, S. Deppe, V. Gassenmeier, F. Kuhfuß, M. Tölle, G.A. Ifrim, B. Frahm, Modeling of Chlorella Vulgaris in Shake Flasks with Respect to Light Intensity and Light Duration, 2020.
ELSA
 

2020 | Konferenz - Vortrag | ELSA-ID: 7936
Integration of prior knowledge and digital tools for uncertainty-based decision support
T. Hernández Rodriguez, B. Frahm, C. Posch, Integration of Prior Knowledge and Digital Tools for Uncertainty-Based Decision Support, 2020.
ELSA
 

2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Modeling of Chlorella vulgaris algae in shake flasks with respect to light intensity and light duration
T. Hernández Rodriguez, S. Deppe, V. Gassenmeier, F. Kuhfuß, M. Tölle, G.A. Ifrim, B. Frahm, Modeling of Chlorella Vulgaris Algae in Shake Flasks with Respect to Light Intensity and Light Duration, Wiley, 2020.
ELSA | DOI
 

2020 | Sammelwerk - Beitrag | ELSA-ID: 2399
Estimation of Process Model Parameters
S. Deppe, B. Frahm, V.C. Hass, T. Hernández Rodríguez, K.B. Kuchemüller, J. Möller, R. Pörtner, in: R. Pörtner (Ed.), Animal Cell Biotechnology: Methods and Protocols, Springer, Berlin ; Heidelberg ; New York, 2020, pp. 213–234.
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