Tanja Hernández Rodriguez

tanja.hernandez@th-owl.de
ID
52466

61 Publikationen

Alle markieren

[61]
2024 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 12402
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken und Marc Wichern. 2024. Comparative Analysis of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator. Chemie Ingenieur Technik 96, Nr. 4: 528–534. doi:10.1002/cite.202300188, .
ELSA | DOI | WoS
 
[60]
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann und Björn Frahm. A systematic, model-based workflow for risk-based decision making in upstream development. DECHEMA e.V.
ELSA
 
[59]
2023 | Konferenz - Poster | ELSA-ID: 11382 | OA
Gassenmeier, Veronika, Fabian Kuhfuß, Sahar Deppe, George Ifrim, Tanja Hernández Rodriguez und Björn Frahm. View on a mechanistic model of Chlorella vulgaris in shake flasks.
ELSA | Download (ext.)
 
[58]
2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm und Björn Frahm. 2023. Model-assisted design strategies for bioprocesses – Advanced statistical methods in industrial upstream cell culture. DECHEMA e.V.
ELSA
 
[57]
2023 | Konferenz - Poster | ELSA-ID: 11487 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm und Miriam Pein-Hackelbusch. Comparison of Preprocessing Methods of Dielectric Spectroscopy  Data and the Effects on Linear Regression . DECHEMA e.V.
ELSA | Download (ext.)
 
[56]
2023 | Konferenz - Poster | ELSA-ID: 10201 | OA
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann und Björn Frahm. 2023. A systematic, model-based workflow for risk-based decision making in upstream development.
ELSA | Download (ext.)
 
[55]
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm und Miriam Pein-Hackelbusch. 2023. Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities. Hg. von Jürgen Jasperneite, Lukasz Wisniewski, Kim Fung Man, und Institute of Electrical and Electronics Engineers . 2023 IEEE 21st International Conference on Industrial Informatics (INDIN). [Piscataway, NJ]: IEEE. doi:10.1109/INDIN51400.2023.10218012, .
ELSA | DOI | Download (ext.)
 
[54]
2023 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11385
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken und Marc Wichern. 2023. Validation and Uncertainty Assessment of a Software‐Integrated Workflow for pH Calculations. Chemie Ingenieur Technik 95, Nr. 12: 1960–1969. doi:10.1002/cite.202300082, .
ELSA | DOI | WoS
 
[53]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11377
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann und Björn Frahm. 2022. Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design. Processes 10, Nr. 5. doi:10.3390/pr10050883, .
ELSA | DOI
 
[52]
2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann und Björn Frahm. A systematic, model-based workflow for risk-based decision making in upstream development.
ELSA
 
[51]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Gassenmeier, Veronika, Sahar Deppe, Tanja Hernández Rodriguez, Fabian Kuhfuß, André Moser, Volker C. Hass, Kim B. Kuchemüller, u. a. 2022. Model-assisted DoE applied to microalgae processes, Current Research in Biotechnology. Current Research in Biotechnology 4: 102–119. doi:10.1016/j.crbiot.2022.01.005, .
ELSA | DOI
 
[50]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
Kuhfuß, Fabian, Veronika Gassenmeier, Sahar Deppe, George Adrian Ifrim, Tanja Hernández Rodriguez und Björn Frahm. 2022. View on a mechanistic model of Chlorella vulgaris in incubated shake flasks. Bioprocess and Biosystems Engineering 45: 15–30. doi:10.1007/s00449-021-02627-2, .
ELSA | DOI
 
[49]
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann und Björn Frahm. 2022. Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design. In: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, hg. von Ralf Pörtner und Johannes Möller, special issue:21–48. Processes : open access journal. Basel: MDPI. doi:https://doi.org/10.3390/pr10050883, .
ELSA | DOI
 
[48]
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2022. Model assisted Design Strategies for Bioprocesses – Advanced statistical methods in industrial upstream cell culture. ACHEMA 2022.
ELSA
 
[47]
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez, Tanja, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm und Björn Frahm. A systematic, model-based approach for decision making in upstream development – Considerations regarding clone selection and cell expansion.
ELSA
 
[46]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11376
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm und Björn Frahm. 2021. Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection—A Simulation Study. Processes 9, Nr. 6. doi:10.3390/pr9060964, .
ELSA | DOI
 
[45]
2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez, Tanja und Björn Frahm. 2021. Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction.
ELSA
 
[44]
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser, André, Johannes Möller, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, Björn Frahm, Ralf Pörtner und Volker C. Hass. 2021. Model-assisted Design of Experiments - Concept, Software and Applications.
ELSA
 
[43]
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm und Björn Frahm. 2021. Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study. In: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, special issue:49–74. Processes : open access journal . Basel: MDPI. doi:10.3390/pr9060964, .
ELSA | DOI
 
[42]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2021. Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train. Bioprocess and Biosystems Engineering 44, Nr. 4: 793–808. doi:10.1007/s00449-020-02488-1 , .
ELSA | DOI
 
[41]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Moser, André, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Björn Frahm, Ralf Pörtner, Volker C. Hass und Johannes Möller. 2021. Model-assisted DoE software: Optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses. Bioprocess and Biosystems Engineering 44, Nr. 4: 683–700. doi:10.1007/s00449-020-02478-3, .
ELSA | DOI
 
[40]
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez, Tanja und Björn Frahm. 2021. Digital Seed Train Twins and Statistical Methods. In: Digital Twins Tools and Concepts for Smart Biomanufacturing, hg. von Christoph Herwig, Ralf Pörtner, und Johannes Möller, 176:97–131. Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer. doi:https://doi.org/10.1007/10_2020_137, .
ELSA | DOI
 
[39]
2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim und Björn Frahm. 2020. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
 
[38]
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2020. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes.
ELSA
 
[37]
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez, Tanja, Björn Frahm und Christoph Posch. 2020. Integration of prior knowledge and digital tools for uncertainty-based decision support.
ELSA
 
[36]
2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim und Björn Frahm. 2020. Modeling of Chlorella vulgaris algae in shake flasks with respect to light intensity and light duration. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Bd. No. 9. Volume 92. Wiley. doi:10.1002/cite.202055235, .
ELSA | DOI
 
[35]
2020 | Konferenzband - Beitrag | ELSA-ID: 7938
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2020. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Bd. No. 9. Volume 92. Wiley. doi:10.1002/cite.202055234, .
ELSA | DOI
 
[34]
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner und Björn Frahm. 2020. Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach. BMC Proceedings. Bd. 14. BioMed Central. doi:10.1186/s12919-020-00188-y, .
ELSA | Dateien verfügbar | DOI
 
[33]
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß, F., M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, S. Deppe, George Adrian Ifrim und Björn Frahm. 2020. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
 
[32]
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe, S., F. Kuhfuß, M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, J. Möller, u. a. 2020. Model-assisted Design of Experiments for algae cultivation.
ELSA
 
[31]
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier und Björn Frahm. 2020. Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
 
[30]
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller, J., J. Müller, Tanja Hernández Rodriguez, K. B. Kuchemüller, L. Arndt, Björn Frahm, R. Eibl, D. Eibl und R. Pörtner. 2019. Workflow for model-assisted design and scale-up of biopharmaceutical production processes.
ELSA
 
[29]
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller, J., K. B. Kuchemüller, A. Moser, V. C. Hass, Tanja Hernández Rodriguez, S. Deppe, Björn Frahm und R. Pörtner. 2019. Model-Assisted Design of Experiments.
ELSA
 
[28]
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner und Björn Frahm. 2019. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
 
[27]
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner und Björn Frahm. 2019. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
 
[26]
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, S. Deppe, George Adrian Ifrim, A. Moser, V. C. Hass, Björn Frahm und R. Pörtner. 2019. Model-Assisted Design of Experiments – Software Toolbox.
ELSA
 
[25]
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe, S., Tanja Hernández Rodriguez, Veronika Gassenmeier, M. Tölle, F. Kuhfuß, J. Möller, K. B. Kuchemüller, u. a. 2019. Model-assisted Design of Experiments for algae cultivation.
ELSA
 
[24]
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier und Björn Frahm. 2019. Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
 
[23]
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner und Björn Frahm. 2019. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
 
[22]
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 | OA
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner und Björn Frahm. 2019. Predicting industrial‐scale cell culture seed trains–A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method. Biotechnology and Bioengineering 116, Nr. 11: 2944–2959. doi:10.1002/bit.27125, .
ELSA | DOI | Download (ext.)
 
[21]
2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez, Tanja, Björn Frahm, Christoph Posch, Julia Schmutzhard und Josef Stettner. 2018. A model-assisted approach for design, optimization and control of bioprocesses – a software tool for seed train simulation and optimization.
ELSA
 
[20]
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez, Tanja, Susan Krull, Volker C. Hass, Johannes Möller, Ralf Pörtner und Björn Frahm. 2018. Model-assisted cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. BMC Proceedings. Bd. 112. BioMed Central. doi:10.1186/s12919-018-0097-x, .
ELSA | Dateien verfügbar | DOI
 
[19]
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller, J., K. B. Kuchemüller, F. Freiberger, P. Levermann, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass und R. Pörtner. 2018. Model-Assisted Design and Optimization of Process Strategies.
ELSA
 
[18]
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez, Tanja, J. Möller, K. B. Kuchemüller, F. Freiberger, P. Levermann, V. C. Hass, Björn Frahm und R. Pörtner. 2018. Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses.
ELSA
 
[17]
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 | OA
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass und R. Pörtner. 2018. Model-Assisted Design of Process Strategies for Cell Culture Processes. American Pharmaceutical Review 3: 39–41.
ELSA | Download (ext.)
 
[16]
2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez, Tanja, S. Kern, O. Platas Barradas, R. Pörtner und Björn Frahm. 2017. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
 
[15]
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner, R., J. Möller, Tanja Hernández Rodriguez, Björn Frahm und V. C. Hass. 2017. Model-assisted design and optimization of biotechnological processes.
ELSA
 
[14]
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez, Tanja, K. S. Koopmann, J. Klaes, S. Kern, O. Platas Barradas, R. Pörtner und Björn Frahm. 2017. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
 
[13]
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez, Tanja, K. S. Koopmann, R. Pörtner und Björn Frahm. 2017. Influence of parameter accuracies in cell culture seed train simulations.
ELSA
 
[12]
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, J. Möller, R. Pörtner und Björn Frahm. 2017. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
 
[11]
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, R. Pörtner und Björn Frahm. 2017. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
 
[10]
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez, Tanja, S. Vörtler, S. Kern, O. Platas Barradas, R. Pörtner und Björn Frahm. 2016. A software tool for biopharmaceutical seed train design and optimization.
ELSA
 
[9]
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann, K. S., Tanja Hernández Rodriguez, S. Vörtler, U. Beshay, J. Möller, R. Pörtner und Björn Frahm. 2016. Simulation of cell culture seed trains – investigation of the influence of parameter inaccuracies.
ELSA
 
[8]
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner und Björn Frahm. 2015. Considerations for cell passaging in cell culture seed trains. BMC proceedings / BioMed Central. Bd. 9. BioMed Central. doi:10.1186/1753-6561-9-s9-p43, .
ELSA | DOI | Download (ext.)
 
[7]
2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm, Björn, R. Pörtner, S. Kern und Tanja Hernández Rodriguez. 2015. Seed train design and optimization for animal cell suspension culture.
ELSA | Dateien verfügbar
 
[6]
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm, Björn, Tanja Hernández Rodriguez, S. Kern, K. S. Koopmann, U. Beshay, O. Platas-Barradas und R. Pörtner. 2015. Seed train design and optimization for animal cell suspension culture.
ELSA
 
[5]
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2015. Considerations for cell passaging in cell culture seed trains.
ELSA
 
[4]
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2015. A software tool for biopharmaceutical seed train design and optimization.
ELSA
 
[3]
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2015. Considerations for cell passaging in cell culture seed trains.
ELSA
 
[2]
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner und Björn Frahm. 2013. Seed train optimization for suspension cell culture. BMC proceedings / BioMed Central . Bd. 7. BioMed Central . doi:10.1186/1753-6561-7-s6-p9, .
ELSA | DOI | Download (ext.)
 
[1]
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2013. Seed train optimization for suspension cell culture.
ELSA
 
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61 Publikationen

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[61]
2024 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 12402
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken und Marc Wichern. 2024. Comparative Analysis of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator. Chemie Ingenieur Technik 96, Nr. 4: 528–534. doi:10.1002/cite.202300188, .
ELSA | DOI | WoS
 
[60]
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann und Björn Frahm. A systematic, model-based workflow for risk-based decision making in upstream development. DECHEMA e.V.
ELSA
 
[59]
2023 | Konferenz - Poster | ELSA-ID: 11382 | OA
Gassenmeier, Veronika, Fabian Kuhfuß, Sahar Deppe, George Ifrim, Tanja Hernández Rodriguez und Björn Frahm. View on a mechanistic model of Chlorella vulgaris in shake flasks.
ELSA | Download (ext.)
 
[58]
2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm und Björn Frahm. 2023. Model-assisted design strategies for bioprocesses – Advanced statistical methods in industrial upstream cell culture. DECHEMA e.V.
ELSA
 
[57]
2023 | Konferenz - Poster | ELSA-ID: 11487 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm und Miriam Pein-Hackelbusch. Comparison of Preprocessing Methods of Dielectric Spectroscopy  Data and the Effects on Linear Regression . DECHEMA e.V.
ELSA | Download (ext.)
 
[56]
2023 | Konferenz - Poster | ELSA-ID: 10201 | OA
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann und Björn Frahm. 2023. A systematic, model-based workflow for risk-based decision making in upstream development.
ELSA | Download (ext.)
 
[55]
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm und Miriam Pein-Hackelbusch. 2023. Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities. Hg. von Jürgen Jasperneite, Lukasz Wisniewski, Kim Fung Man, und Institute of Electrical and Electronics Engineers . 2023 IEEE 21st International Conference on Industrial Informatics (INDIN). [Piscataway, NJ]: IEEE. doi:10.1109/INDIN51400.2023.10218012, .
ELSA | DOI | Download (ext.)
 
[54]
2023 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11385
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken und Marc Wichern. 2023. Validation and Uncertainty Assessment of a Software‐Integrated Workflow for pH Calculations. Chemie Ingenieur Technik 95, Nr. 12: 1960–1969. doi:10.1002/cite.202300082, .
ELSA | DOI | WoS
 
[53]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11377
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann und Björn Frahm. 2022. Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design. Processes 10, Nr. 5. doi:10.3390/pr10050883, .
ELSA | DOI
 
[52]
2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann und Björn Frahm. A systematic, model-based workflow for risk-based decision making in upstream development.
ELSA
 
[51]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Gassenmeier, Veronika, Sahar Deppe, Tanja Hernández Rodriguez, Fabian Kuhfuß, André Moser, Volker C. Hass, Kim B. Kuchemüller, u. a. 2022. Model-assisted DoE applied to microalgae processes, Current Research in Biotechnology. Current Research in Biotechnology 4: 102–119. doi:10.1016/j.crbiot.2022.01.005, .
ELSA | DOI
 
[50]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
Kuhfuß, Fabian, Veronika Gassenmeier, Sahar Deppe, George Adrian Ifrim, Tanja Hernández Rodriguez und Björn Frahm. 2022. View on a mechanistic model of Chlorella vulgaris in incubated shake flasks. Bioprocess and Biosystems Engineering 45: 15–30. doi:10.1007/s00449-021-02627-2, .
ELSA | DOI
 
[49]
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann und Björn Frahm. 2022. Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design. In: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, hg. von Ralf Pörtner und Johannes Möller, special issue:21–48. Processes : open access journal. Basel: MDPI. doi:https://doi.org/10.3390/pr10050883, .
ELSA | DOI
 
[48]
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2022. Model assisted Design Strategies for Bioprocesses – Advanced statistical methods in industrial upstream cell culture. ACHEMA 2022.
ELSA
 
[47]
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez, Tanja, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm und Björn Frahm. A systematic, model-based approach for decision making in upstream development – Considerations regarding clone selection and cell expansion.
ELSA
 
[46]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11376
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm und Björn Frahm. 2021. Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection—A Simulation Study. Processes 9, Nr. 6. doi:10.3390/pr9060964, .
ELSA | DOI
 
[45]
2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez, Tanja und Björn Frahm. 2021. Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction.
ELSA
 
[44]
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser, André, Johannes Möller, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, Björn Frahm, Ralf Pörtner und Volker C. Hass. 2021. Model-assisted Design of Experiments - Concept, Software and Applications.
ELSA
 
[43]
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm und Björn Frahm. 2021. Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study. In: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, special issue:49–74. Processes : open access journal . Basel: MDPI. doi:10.3390/pr9060964, .
ELSA | DOI
 
[42]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2021. Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train. Bioprocess and Biosystems Engineering 44, Nr. 4: 793–808. doi:10.1007/s00449-020-02488-1 , .
ELSA | DOI
 
[41]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Moser, André, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Björn Frahm, Ralf Pörtner, Volker C. Hass und Johannes Möller. 2021. Model-assisted DoE software: Optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses. Bioprocess and Biosystems Engineering 44, Nr. 4: 683–700. doi:10.1007/s00449-020-02478-3, .
ELSA | DOI
 
[40]
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez, Tanja und Björn Frahm. 2021. Digital Seed Train Twins and Statistical Methods. In: Digital Twins Tools and Concepts for Smart Biomanufacturing, hg. von Christoph Herwig, Ralf Pörtner, und Johannes Möller, 176:97–131. Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer. doi:https://doi.org/10.1007/10_2020_137, .
ELSA | DOI
 
[39]
2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim und Björn Frahm. 2020. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
 
[38]
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2020. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes.
ELSA
 
[37]
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez, Tanja, Björn Frahm und Christoph Posch. 2020. Integration of prior knowledge and digital tools for uncertainty-based decision support.
ELSA
 
[36]
2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim und Björn Frahm. 2020. Modeling of Chlorella vulgaris algae in shake flasks with respect to light intensity and light duration. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Bd. No. 9. Volume 92. Wiley. doi:10.1002/cite.202055235, .
ELSA | DOI
 
[35]
2020 | Konferenzband - Beitrag | ELSA-ID: 7938
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner und Björn Frahm. 2020. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Bd. No. 9. Volume 92. Wiley. doi:10.1002/cite.202055234, .
ELSA | DOI
 
[34]
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner und Björn Frahm. 2020. Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach. BMC Proceedings. Bd. 14. BioMed Central. doi:10.1186/s12919-020-00188-y, .
ELSA | Dateien verfügbar | DOI
 
[33]
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß, F., M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, S. Deppe, George Adrian Ifrim und Björn Frahm. 2020. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
 
[32]
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe, S., F. Kuhfuß, M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, J. Möller, u. a. 2020. Model-assisted Design of Experiments for algae cultivation.
ELSA
 
[31]
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier und Björn Frahm. 2020. Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
 
[30]
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller, J., J. Müller, Tanja Hernández Rodriguez, K. B. Kuchemüller, L. Arndt, Björn Frahm, R. Eibl, D. Eibl und R. Pörtner. 2019. Workflow for model-assisted design and scale-up of biopharmaceutical production processes.
ELSA
 
[29]
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller, J., K. B. Kuchemüller, A. Moser, V. C. Hass, Tanja Hernández Rodriguez, S. Deppe, Björn Frahm und R. Pörtner. 2019. Model-Assisted Design of Experiments.
ELSA
 
[28]
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner und Björn Frahm. 2019. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
 
[27]
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner und Björn Frahm. 2019. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
 
[26]
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, S. Deppe, George Adrian Ifrim, A. Moser, V. C. Hass, Björn Frahm und R. Pörtner. 2019. Model-Assisted Design of Experiments – Software Toolbox.
ELSA
 
[25]
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe, S., Tanja Hernández Rodriguez, Veronika Gassenmeier, M. Tölle, F. Kuhfuß, J. Möller, K. B. Kuchemüller, u. a. 2019. Model-assisted Design of Experiments for algae cultivation.
ELSA
 
[24]
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier und Björn Frahm. 2019. Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
 
[23]
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner und Björn Frahm. 2019. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
 
[22]
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 | OA
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner und Björn Frahm. 2019. Predicting industrial‐scale cell culture seed trains–A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method. Biotechnology and Bioengineering 116, Nr. 11: 2944–2959. doi:10.1002/bit.27125, .
ELSA | DOI | Download (ext.)
 
[21]
2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez, Tanja, Björn Frahm, Christoph Posch, Julia Schmutzhard und Josef Stettner. 2018. A model-assisted approach for design, optimization and control of bioprocesses – a software tool for seed train simulation and optimization.
ELSA
 
[20]
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez, Tanja, Susan Krull, Volker C. Hass, Johannes Möller, Ralf Pörtner und Björn Frahm. 2018. Model-assisted cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. BMC Proceedings. Bd. 112. BioMed Central. doi:10.1186/s12919-018-0097-x, .
ELSA | Dateien verfügbar | DOI
 
[19]
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller, J., K. B. Kuchemüller, F. Freiberger, P. Levermann, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass und R. Pörtner. 2018. Model-Assisted Design and Optimization of Process Strategies.
ELSA
 
[18]
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez, Tanja, J. Möller, K. B. Kuchemüller, F. Freiberger, P. Levermann, V. C. Hass, Björn Frahm und R. Pörtner. 2018. Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses.
ELSA
 
[17]
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 | OA
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass und R. Pörtner. 2018. Model-Assisted Design of Process Strategies for Cell Culture Processes. American Pharmaceutical Review 3: 39–41.
ELSA | Download (ext.)
 
[16]
2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez, Tanja, S. Kern, O. Platas Barradas, R. Pörtner und Björn Frahm. 2017. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
 
[15]
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner, R., J. Möller, Tanja Hernández Rodriguez, Björn Frahm und V. C. Hass. 2017. Model-assisted design and optimization of biotechnological processes.
ELSA
 
[14]
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez, Tanja, K. S. Koopmann, J. Klaes, S. Kern, O. Platas Barradas, R. Pörtner und Björn Frahm. 2017. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
 
[13]
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez, Tanja, K. S. Koopmann, R. Pörtner und Björn Frahm. 2017. Influence of parameter accuracies in cell culture seed train simulations.
ELSA
 
[12]
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, J. Möller, R. Pörtner und Björn Frahm. 2017. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
 
[11]
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, R. Pörtner und Björn Frahm. 2017. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
 
[10]
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez, Tanja, S. Vörtler, S. Kern, O. Platas Barradas, R. Pörtner und Björn Frahm. 2016. A software tool for biopharmaceutical seed train design and optimization.
ELSA
 
[9]
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann, K. S., Tanja Hernández Rodriguez, S. Vörtler, U. Beshay, J. Möller, R. Pörtner und Björn Frahm. 2016. Simulation of cell culture seed trains – investigation of the influence of parameter inaccuracies.
ELSA
 
[8]
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner und Björn Frahm. 2015. Considerations for cell passaging in cell culture seed trains. BMC proceedings / BioMed Central. Bd. 9. BioMed Central. doi:10.1186/1753-6561-9-s9-p43, .
ELSA | DOI | Download (ext.)
 
[7]
2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm, Björn, R. Pörtner, S. Kern und Tanja Hernández Rodriguez. 2015. Seed train design and optimization for animal cell suspension culture.
ELSA | Dateien verfügbar
 
[6]
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm, Björn, Tanja Hernández Rodriguez, S. Kern, K. S. Koopmann, U. Beshay, O. Platas-Barradas und R. Pörtner. 2015. Seed train design and optimization for animal cell suspension culture.
ELSA
 
[5]
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2015. Considerations for cell passaging in cell culture seed trains.
ELSA
 
[4]
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2015. A software tool for biopharmaceutical seed train design and optimization.
ELSA
 
[3]
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2015. Considerations for cell passaging in cell culture seed trains.
ELSA
 
[2]
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner und Björn Frahm. 2013. Seed train optimization for suspension cell culture. BMC proceedings / BioMed Central . Bd. 7. BioMed Central . doi:10.1186/1753-6561-7-s6-p9, .
ELSA | DOI | Download (ext.)
 
[1]
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, Tanja, R. Pörtner und Björn Frahm. 2013. Seed train optimization for suspension cell culture.
ELSA
 
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