Tanja Hernández Rodriguez

tanja.hernandez@th-owl.de
ID
52466

61 Publikationen

Alle markieren

[61]
2024 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 12402
Kosse P, Hernández Rodriguez T, Frahm B, Lübken M, Wichern M. Comparative Analysis of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator. Chemie Ingenieur Technik. 2024;96(4):528–34.
ELSA | DOI | WoS
 
[60]
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez T, Ramm S, Lange-Hegermann M, Frahm B. A systematic, model-based workflow for risk-based decision making in upstream development. DECHEMA e.V.;
ELSA
 
[59]
2023 | Konferenz - Poster | ELSA-ID: 11382 | OA
Gassenmeier V, Kuhfuß F, Deppe S, Ifrim G, Hernández Rodriguez T, Frahm B. View on a mechanistic model of Chlorella vulgaris in shake flasks.
ELSA | Download (ext.)
 
[58]
2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez T, Posch C, Pörtner R, Lange-Hegermann M, Wurm FM, Frahm B. Model-assisted design strategies for bioprocesses – Advanced statistical methods in industrial upstream cell culture. DECHEMA e.V.; 2023.
ELSA
 
[57]
2023 | Konferenz - Poster | ELSA-ID: 11487 | OA
Ramm S, Hernández Rodriguez T, Frahm B, Pein-Hackelbusch M. Comparison of Preprocessing Methods of Dielectric Spectroscopy  Data and the Effects on Linear Regression . DECHEMA e.V.;
ELSA | Download (ext.)
 
[56]
2023 | Konferenz - Poster | ELSA-ID: 10201 | OA
Hernández Rodriguez T, Ramm S, Lange-Hegermann M, Frahm B. A systematic, model-based workflow for risk-based decision making in upstream development. 2023.
ELSA | Download (ext.)
 
[55]
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 | OA
Ramm S, Hernández Rodriguez T, Frahm B, Pein-Hackelbusch M. Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities. Jasperneite J, Wisniewski L, Fung Man K, Institute of Electrical and Electronics Engineers , editors. 2023 IEEE 21st International Conference on Industrial Informatics (INDIN). [Piscataway, NJ]: IEEE; 2023.
ELSA | DOI | Download (ext.)
 
[54]
2023 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11385
Kosse P, Hernández Rodriguez T, Frahm B, Lübken M, Wichern M. Validation and Uncertainty Assessment of a Software‐Integrated Workflow for pH Calculations. Chemie Ingenieur Technik. 2023;95(12):1960–9.
ELSA | DOI | WoS
 
[53]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11377
Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design. Processes. 2022;10(5).
ELSA | DOI
 
[52]
2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez T, Ramm S, Lange-Hegermann M, Frahm B. A systematic, model-based workflow for risk-based decision making in upstream development.
ELSA
 
[51]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Gassenmeier V, Deppe S, Hernández Rodriguez T, Kuhfuß F, Moser A, Hass VC, et al. Model-assisted DoE applied to microalgae processes, Current Research in Biotechnology. Current Research in Biotechnology. 2022;4:102–19.
ELSA | DOI
 
[50]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
Kuhfuß F, Gassenmeier V, Deppe S, Ifrim GA, Hernández Rodriguez T, Frahm B. View on a mechanistic model of Chlorella vulgaris in incubated shake flasks. Bioprocess and Biosystems Engineering. 2022;45:15–30.
ELSA | DOI
 
[49]
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design. In: Pörtner R, Möller J, editors. Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing. Basel: MDPI; 2022. p. 21–48. (Processes : open access journal; vol. special issue).
ELSA | DOI
 
[48]
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Model assisted Design Strategies for Bioprocesses – Advanced statistical methods in industrial upstream cell culture. ACHEMA 2022. 2022.
ELSA
 
[47]
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez T, Pörtner R, Lange-Hegermann M, Wurm FM, Frahm B. A systematic, model-based approach for decision making in upstream development – Considerations regarding clone selection and cell expansion.
ELSA
 
[46]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11376
Hernández Rodriguez T, Morerod S, Pörtner R, Wurm FM, Frahm B. Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection—A Simulation Study. Processes. 2021;9(6).
ELSA | DOI
 
[45]
2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez T, Frahm B. Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction. 2021.
ELSA
 
[44]
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser A, Möller J, Kuchemüller KB, Deppe S, Hernández Rodriguez T, Gassenmeier V, et al. Model-assisted Design of Experiments - Concept, Software and Applications. 2021.
ELSA
 
[43]
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez T, Morerod S, Pörtner R, Wurm FM, Frahm B. Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study. In: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing. Basel: MDPI; 2021. p. 49–74. (Processes : open access journal ; vol. special issue).
ELSA | DOI
 
[42]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train. Bioprocess and Biosystems Engineering. 2021;44(4):793–808.
ELSA | DOI
 
[41]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Moser A, Kuchemüller KB, Deppe S, Hernández Rodriguez T, Frahm B, Pörtner R, et al. Model-assisted DoE software: Optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses. Bioprocess and Biosystems Engineering. 2021;44(4):683–700.
ELSA | DOI
 
[40]
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez T, Frahm B. Digital Seed Train Twins and Statistical Methods. In: Herwig C, Pörtner R, Möller J, editors. Digital Twins Tools and Concepts for Smart Biomanufacturing. Berlin, Heidelberg: Springer; 2021. p. 97–131. (Advances in Biochemical Engineering/Biotechnology; vol. 176).
ELSA | DOI
 
[39]
2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez T, Deppe S, Gassenmeier V, Kuhfuß F, Tölle M, Ifrim GA, et al. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration. 2020.
ELSA
 
[38]
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes. 2020.
ELSA
 
[37]
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez T, Frahm B, Posch C. Integration of prior knowledge and digital tools for uncertainty-based decision support. 2020.
ELSA
 
[36]
2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Hernández Rodriguez T, Deppe S, Gassenmeier V, Kuhfuß F, Tölle M, Ifrim GA, et al. Modeling of Chlorella vulgaris algae in shake flasks with respect to light intensity and light duration. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Wiley; 2020. (Volume 92; vol. No. 9).
ELSA | DOI
 
[35]
2020 | Konferenzband - Beitrag | ELSA-ID: 7938
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Wiley; 2020. (Volume 92; vol. No. 9).
ELSA | DOI
 
[34]
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs Claus , Pörtner R, et al. Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach. Vol. 14, BMC Proceedings. BioMed Central; 2020.
ELSA | Dateien verfügbar | DOI
 
[33]
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß F, Tölle M, Hernández Rodriguez T, Gassenmeier V, Deppe S, Ifrim GA, et al. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration. 2020.
ELSA
 
[32]
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe S, Kuhfuß F, Tölle M, Hernández Rodriguez T, Gassenmeier V, Ifrim GA, et al. Model-assisted Design of Experiments for algae cultivation. 2020.
ELSA
 
[31]
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim GA, Deppe S, Hernández Rodriguez T, Gassenmeier V, Frahm B. Modeling of microalgae in an air-lift photobioreactor for biomass production. 2020.
ELSA
 
[30]
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller J, Müller J, Hernández Rodriguez T, Kuchemüller KB, Arndt L, Frahm B, et al. Workflow for model-assisted design and scale-up of biopharmaceutical production processes. 2019.
ELSA
 
[29]
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller J, Kuchemüller KB, Moser A, Hass VC, Hernández Rodriguez T, Deppe S, et al. Model-Assisted Design of Experiments. 2019.
ELSA
 
[28]
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs J, Pörtner R, et al. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating. 2019.
ELSA
 
[27]
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs J, Pörtner R, et al. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating. 2019.
ELSA
 
[26]
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller J, Kuchemüller KB, Hernández Rodriguez T, Deppe S, Ifrim GA, Moser A, et al. Model-Assisted Design of Experiments – Software Toolbox. 2019.
ELSA
 
[25]
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe S, Hernández Rodriguez T, Gassenmeier V, Tölle M, Kuhfuß F, Möller J, et al. Model-assisted Design of Experiments for algae cultivation. 2019.
ELSA
 
[24]
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim GA, Deppe S, Hernández Rodriguez T, Gassenmeier V, Frahm B. Modeling of microalgae in an air-lift photobioreactor for biomass production. 2019.
ELSA
 
[23]
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs J, Pörtner R, et al. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating. 2019.
ELSA
 
[22]
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 | OA
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs C, Pörtner R, et al. Predicting industrial‐scale cell culture seed trains–A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method. Biotechnology and Bioengineering. 2019;116(11):2944–59.
ELSA | DOI | Download (ext.)
 
[21]
2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez T, Frahm B, Posch C, Schmutzhard J, Stettner J. A model-assisted approach for design, optimization and control of bioprocesses – a software tool for seed train simulation and optimization. 2018.
ELSA
 
[20]
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez T, Krull S, Hass VC, Möller J, Pörtner R, Frahm B. Model-assisted cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. Vol. 112, BMC Proceedings. BioMed Central; 2018.
ELSA | Dateien verfügbar | DOI
 
[19]
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller J, Kuchemüller KB, Freiberger F, Levermann P, Hernández Rodriguez T, Frahm B, et al. Model-Assisted Design and Optimization of Process Strategies. 2018.
ELSA
 
[18]
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez T, Möller J, Kuchemüller KB, Freiberger F, Levermann P, Hass VC, et al. Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses. 2018.
ELSA
 
[17]
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 | OA
Möller J, Kuchemüller KB, Hernández Rodriguez T, Frahm B, Hass VC, Pörtner R. Model-Assisted Design of Process Strategies for Cell Culture Processes. American Pharmaceutical Review. 2018;3:39–41.
ELSA | Download (ext.)
 
[16]
2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez T, Kern S, Platas Barradas O, Pörtner R, Frahm B. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren. 2017.
ELSA
 
[15]
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner R, Möller J, Hernández Rodriguez T, Frahm B, Hass VC. Model-assisted design and optimization of biotechnological processes. 2017.
ELSA
 
[14]
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez T, Koopmann KS, Klaes J, Kern S, Platas Barradas O, Pörtner R, et al. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren. 2017.
ELSA
 
[13]
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez T, Koopmann KS, Pörtner R, Frahm B. Influence of parameter accuracies in cell culture seed train simulations. 2017.
ELSA
 
[12]
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez T, Krull S, Hass VC, Möller J, Pörtner R, Frahm B. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. 2017.
ELSA
 
[11]
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez T, Krull S, Hass VC, Pörtner R, Frahm B. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. 2017.
ELSA
 
[10]
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez T, Vörtler S, Kern S, Platas Barradas O, Pörtner R, Frahm B. A software tool for biopharmaceutical seed train design and optimization. 2016.
ELSA
 
[9]
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann KS, Hernández Rodriguez T, Vörtler S, Beshay U, Möller J, Pörtner R, et al. Simulation of cell culture seed trains – investigation of the influence of parameter inaccuracies. 2016.
ELSA
 
[8]
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 | OA
Hernández Rodriguez T, Pörtner R, Frahm B. Considerations for cell passaging in cell culture seed trains. Vol. 9, BMC proceedings / BioMed Central. BioMed Central; 2015.
ELSA | DOI | Download (ext.)
 
[7]
2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm B, Pörtner R, Kern S, Hernández Rodriguez T. Seed train design and optimization for animal cell suspension culture. 2015.
ELSA | Dateien verfügbar
 
[6]
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm B, Hernández Rodriguez T, Kern S, Koopmann KS, Beshay U, Platas-Barradas O, et al. Seed train design and optimization for animal cell suspension culture. 2015.
ELSA
 
[5]
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez T, Pörtner R, Frahm B. Considerations for cell passaging in cell culture seed trains. 2015.
ELSA
 
[4]
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez T, Pörtner R, Frahm B. A software tool for biopharmaceutical seed train design and optimization. 2015.
ELSA
 
[3]
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez T, Pörtner R, Frahm B. Considerations for cell passaging in cell culture seed trains. 2015.
ELSA
 
[2]
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 | OA
Hernández Rodriguez T, Pörtner R, Frahm B. Seed train optimization for suspension cell culture. Vol. 7, BMC proceedings / BioMed Central . BioMed Central ; 2013.
ELSA | DOI | Download (ext.)
 
[1]
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez T, Pörtner R, Frahm B. Seed train optimization for suspension cell culture. 2013.
ELSA
 
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61 Publikationen

Alle markieren

[61]
2024 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 12402
Kosse P, Hernández Rodriguez T, Frahm B, Lübken M, Wichern M. Comparative Analysis of pH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator. Chemie Ingenieur Technik. 2024;96(4):528–34.
ELSA | DOI | WoS
 
[60]
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez T, Ramm S, Lange-Hegermann M, Frahm B. A systematic, model-based workflow for risk-based decision making in upstream development. DECHEMA e.V.;
ELSA
 
[59]
2023 | Konferenz - Poster | ELSA-ID: 11382 | OA
Gassenmeier V, Kuhfuß F, Deppe S, Ifrim G, Hernández Rodriguez T, Frahm B. View on a mechanistic model of Chlorella vulgaris in shake flasks.
ELSA | Download (ext.)
 
[58]
2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez T, Posch C, Pörtner R, Lange-Hegermann M, Wurm FM, Frahm B. Model-assisted design strategies for bioprocesses – Advanced statistical methods in industrial upstream cell culture. DECHEMA e.V.; 2023.
ELSA
 
[57]
2023 | Konferenz - Poster | ELSA-ID: 11487 | OA
Ramm S, Hernández Rodriguez T, Frahm B, Pein-Hackelbusch M. Comparison of Preprocessing Methods of Dielectric Spectroscopy  Data and the Effects on Linear Regression . DECHEMA e.V.;
ELSA | Download (ext.)
 
[56]
2023 | Konferenz - Poster | ELSA-ID: 10201 | OA
Hernández Rodriguez T, Ramm S, Lange-Hegermann M, Frahm B. A systematic, model-based workflow for risk-based decision making in upstream development. 2023.
ELSA | Download (ext.)
 
[55]
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 | OA
Ramm S, Hernández Rodriguez T, Frahm B, Pein-Hackelbusch M. Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities. Jasperneite J, Wisniewski L, Fung Man K, Institute of Electrical and Electronics Engineers , editors. 2023 IEEE 21st International Conference on Industrial Informatics (INDIN). [Piscataway, NJ]: IEEE; 2023.
ELSA | DOI | Download (ext.)
 
[54]
2023 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11385
Kosse P, Hernández Rodriguez T, Frahm B, Lübken M, Wichern M. Validation and Uncertainty Assessment of a Software‐Integrated Workflow for pH Calculations. Chemie Ingenieur Technik. 2023;95(12):1960–9.
ELSA | DOI | WoS
 
[53]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11377
Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design. Processes. 2022;10(5).
ELSA | DOI
 
[52]
2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez T, Ramm S, Lange-Hegermann M, Frahm B. A systematic, model-based workflow for risk-based decision making in upstream development.
ELSA
 
[51]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Gassenmeier V, Deppe S, Hernández Rodriguez T, Kuhfuß F, Moser A, Hass VC, et al. Model-assisted DoE applied to microalgae processes, Current Research in Biotechnology. Current Research in Biotechnology. 2022;4:102–19.
ELSA | DOI
 
[50]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
Kuhfuß F, Gassenmeier V, Deppe S, Ifrim GA, Hernández Rodriguez T, Frahm B. View on a mechanistic model of Chlorella vulgaris in incubated shake flasks. Bioprocess and Biosystems Engineering. 2022;45:15–30.
ELSA | DOI
 
[49]
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez T, Sekulic A, Lange-Hegermann M, Frahm B. Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design. In: Pörtner R, Möller J, editors. Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing. Basel: MDPI; 2022. p. 21–48. (Processes : open access journal; vol. special issue).
ELSA | DOI
 
[48]
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Model assisted Design Strategies for Bioprocesses – Advanced statistical methods in industrial upstream cell culture. ACHEMA 2022. 2022.
ELSA
 
[47]
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez T, Pörtner R, Lange-Hegermann M, Wurm FM, Frahm B. A systematic, model-based approach for decision making in upstream development – Considerations regarding clone selection and cell expansion.
ELSA
 
[46]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11376
Hernández Rodriguez T, Morerod S, Pörtner R, Wurm FM, Frahm B. Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection—A Simulation Study. Processes. 2021;9(6).
ELSA | DOI
 
[45]
2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez T, Frahm B. Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction. 2021.
ELSA
 
[44]
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser A, Möller J, Kuchemüller KB, Deppe S, Hernández Rodriguez T, Gassenmeier V, et al. Model-assisted Design of Experiments - Concept, Software and Applications. 2021.
ELSA
 
[43]
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez T, Morerod S, Pörtner R, Wurm FM, Frahm B. Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study. In: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing. Basel: MDPI; 2021. p. 49–74. (Processes : open access journal ; vol. special issue).
ELSA | DOI
 
[42]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train. Bioprocess and Biosystems Engineering. 2021;44(4):793–808.
ELSA | DOI
 
[41]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Moser A, Kuchemüller KB, Deppe S, Hernández Rodriguez T, Frahm B, Pörtner R, et al. Model-assisted DoE software: Optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses. Bioprocess and Biosystems Engineering. 2021;44(4):683–700.
ELSA | DOI
 
[40]
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez T, Frahm B. Digital Seed Train Twins and Statistical Methods. In: Herwig C, Pörtner R, Möller J, editors. Digital Twins Tools and Concepts for Smart Biomanufacturing. Berlin, Heidelberg: Springer; 2021. p. 97–131. (Advances in Biochemical Engineering/Biotechnology; vol. 176).
ELSA | DOI
 
[39]
2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez T, Deppe S, Gassenmeier V, Kuhfuß F, Tölle M, Ifrim GA, et al. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration. 2020.
ELSA
 
[38]
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes. 2020.
ELSA
 
[37]
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez T, Frahm B, Posch C. Integration of prior knowledge and digital tools for uncertainty-based decision support. 2020.
ELSA
 
[36]
2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Hernández Rodriguez T, Deppe S, Gassenmeier V, Kuhfuß F, Tölle M, Ifrim GA, et al. Modeling of Chlorella vulgaris algae in shake flasks with respect to light intensity and light duration. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Wiley; 2020. (Volume 92; vol. No. 9).
ELSA | DOI
 
[35]
2020 | Konferenzband - Beitrag | ELSA-ID: 7938
Hernández Rodriguez T, Posch C, Pörtner R, Frahm B. Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes. Chemie Ingenieur Technik, Tagungsband zur 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020. Wiley; 2020. (Volume 92; vol. No. 9).
ELSA | DOI
 
[34]
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs Claus , Pörtner R, et al. Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach. Vol. 14, BMC Proceedings. BioMed Central; 2020.
ELSA | Dateien verfügbar | DOI
 
[33]
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß F, Tölle M, Hernández Rodriguez T, Gassenmeier V, Deppe S, Ifrim GA, et al. Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration. 2020.
ELSA
 
[32]
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe S, Kuhfuß F, Tölle M, Hernández Rodriguez T, Gassenmeier V, Ifrim GA, et al. Model-assisted Design of Experiments for algae cultivation. 2020.
ELSA
 
[31]
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim GA, Deppe S, Hernández Rodriguez T, Gassenmeier V, Frahm B. Modeling of microalgae in an air-lift photobioreactor for biomass production. 2020.
ELSA
 
[30]
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller J, Müller J, Hernández Rodriguez T, Kuchemüller KB, Arndt L, Frahm B, et al. Workflow for model-assisted design and scale-up of biopharmaceutical production processes. 2019.
ELSA
 
[29]
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller J, Kuchemüller KB, Moser A, Hass VC, Hernández Rodriguez T, Deppe S, et al. Model-Assisted Design of Experiments. 2019.
ELSA
 
[28]
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs J, Pörtner R, et al. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating. 2019.
ELSA
 
[27]
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs J, Pörtner R, et al. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating. 2019.
ELSA
 
[26]
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller J, Kuchemüller KB, Hernández Rodriguez T, Deppe S, Ifrim GA, Moser A, et al. Model-Assisted Design of Experiments – Software Toolbox. 2019.
ELSA
 
[25]
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe S, Hernández Rodriguez T, Gassenmeier V, Tölle M, Kuhfuß F, Möller J, et al. Model-assisted Design of Experiments for algae cultivation. 2019.
ELSA
 
[24]
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim GA, Deppe S, Hernández Rodriguez T, Gassenmeier V, Frahm B. Modeling of microalgae in an air-lift photobioreactor for biomass production. 2019.
ELSA
 
[23]
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs J, Pörtner R, et al. Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating. 2019.
ELSA
 
[22]
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 | OA
Hernández Rodriguez T, Posch C, Schmutzhard J, Stettner J, Weihs C, Pörtner R, et al. Predicting industrial‐scale cell culture seed trains–A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method. Biotechnology and Bioengineering. 2019;116(11):2944–59.
ELSA | DOI | Download (ext.)
 
[21]
2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez T, Frahm B, Posch C, Schmutzhard J, Stettner J. A model-assisted approach for design, optimization and control of bioprocesses – a software tool for seed train simulation and optimization. 2018.
ELSA
 
[20]
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez T, Krull S, Hass VC, Möller J, Pörtner R, Frahm B. Model-assisted cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. Vol. 112, BMC Proceedings. BioMed Central; 2018.
ELSA | Dateien verfügbar | DOI
 
[19]
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller J, Kuchemüller KB, Freiberger F, Levermann P, Hernández Rodriguez T, Frahm B, et al. Model-Assisted Design and Optimization of Process Strategies. 2018.
ELSA
 
[18]
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez T, Möller J, Kuchemüller KB, Freiberger F, Levermann P, Hass VC, et al. Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses. 2018.
ELSA
 
[17]
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 | OA
Möller J, Kuchemüller KB, Hernández Rodriguez T, Frahm B, Hass VC, Pörtner R. Model-Assisted Design of Process Strategies for Cell Culture Processes. American Pharmaceutical Review. 2018;3:39–41.
ELSA | Download (ext.)
 
[16]
2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez T, Kern S, Platas Barradas O, Pörtner R, Frahm B. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren. 2017.
ELSA
 
[15]
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner R, Möller J, Hernández Rodriguez T, Frahm B, Hass VC. Model-assisted design and optimization of biotechnological processes. 2017.
ELSA
 
[14]
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez T, Koopmann KS, Klaes J, Kern S, Platas Barradas O, Pörtner R, et al. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren. 2017.
ELSA
 
[13]
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez T, Koopmann KS, Pörtner R, Frahm B. Influence of parameter accuracies in cell culture seed train simulations. 2017.
ELSA
 
[12]
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez T, Krull S, Hass VC, Möller J, Pörtner R, Frahm B. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. 2017.
ELSA
 
[11]
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez T, Krull S, Hass VC, Pörtner R, Frahm B. Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization. 2017.
ELSA
 
[10]
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez T, Vörtler S, Kern S, Platas Barradas O, Pörtner R, Frahm B. A software tool for biopharmaceutical seed train design and optimization. 2016.
ELSA
 
[9]
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann KS, Hernández Rodriguez T, Vörtler S, Beshay U, Möller J, Pörtner R, et al. Simulation of cell culture seed trains – investigation of the influence of parameter inaccuracies. 2016.
ELSA
 
[8]
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 | OA
Hernández Rodriguez T, Pörtner R, Frahm B. Considerations for cell passaging in cell culture seed trains. Vol. 9, BMC proceedings / BioMed Central. BioMed Central; 2015.
ELSA | DOI | Download (ext.)
 
[7]
2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm B, Pörtner R, Kern S, Hernández Rodriguez T. Seed train design and optimization for animal cell suspension culture. 2015.
ELSA | Dateien verfügbar
 
[6]
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm B, Hernández Rodriguez T, Kern S, Koopmann KS, Beshay U, Platas-Barradas O, et al. Seed train design and optimization for animal cell suspension culture. 2015.
ELSA
 
[5]
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez T, Pörtner R, Frahm B. Considerations for cell passaging in cell culture seed trains. 2015.
ELSA
 
[4]
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez T, Pörtner R, Frahm B. A software tool for biopharmaceutical seed train design and optimization. 2015.
ELSA
 
[3]
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez T, Pörtner R, Frahm B. Considerations for cell passaging in cell culture seed trains. 2015.
ELSA
 
[2]
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 | OA
Hernández Rodriguez T, Pörtner R, Frahm B. Seed train optimization for suspension cell culture. Vol. 7, BMC proceedings / BioMed Central . BioMed Central ; 2013.
ELSA | DOI | Download (ext.)
 
[1]
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez T, Pörtner R, Frahm B. Seed train optimization for suspension cell culture. 2013.
ELSA
 
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