Björn Frahm

Fachbereich 4 Life Science Technologies
bjoern.frahm@th-owl.de
ID
45666

168 Publikationen

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[168]
2024 | Konferenz - Vortrag | ELSA-ID: 12021
Segermann, Jan, Mario Luttmann, André Blome, Sebastian Feldt, Sujee Sivanesan, Christoph-Alexander Holst, Volker Lohweg, Björn Frahm, and Ulrich Müller. Die Rolle von ML-Modellen in der Lebensmitteltechnologie: Eine Fallstudie zur Sauerteigfermentation mit NIR-Spektroskopie, 2024.
ELSA
 
[167]
2024 | Konferenz - Vortrag | ELSA-ID: 12022
Luttmann, Mario, André Blome, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Erkenntnisse zur Nutzung von Photogrammmetrie für die Untersuchung des Bräunungsverhaltens von Weizenbrötchen, 2024.
ELSA
 
[166]
2024 | Konferenz - Poster | ELSA-ID: 12395
Müller, Carolin, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. Investigation of Microbial Spoilage in Vegan Foods, 2024.
ELSA
 
[165]
2024 | Konferenz - Poster | ELSA-ID: 12396
Gassenmeier, Veronika, Giovanni Campolongo, and Björn Frahm. Dissolved Carbon Dioxide in Addition to Dissolved Oxygen for In-Situ Monitoring of Hybridoma Cell Culture, 2024.
ELSA
 
[164]
2024 | Konferenz - Poster | ELSA-ID: 12397
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Process Optimization in Baked Goods Production Using Inline Sensors and Objective Product Evaluation, 2024.
ELSA
 
[163]
2024 | Preprint | ELSA-ID: 12400 | OA
Ramm, Selina, Ulrich Odefey, Björn Frahm, and Miriam Pein-Hackelbusch. “Semi-Automated vs. Manual: Comparative Study of Cell Culture Counting Methods Using Validation Parameters.” bioRxiv, 2024. https://doi.org/10.1101/2024.05.30.596619.
ELSA | DOI | Download (ext.)
 
[162]
2024 | Konferenz - Poster | ELSA-ID: 10957
Reinhardt, Lena, Veronika Gassenmeier, Sebastian Feldt, Sebastian Plate, Martin Tremmel, Björn Frahm, and Martin Stosch. Mycelium-Based Materials from Residues of the Regional Wood Industry, n.d.
ELSA
 
[161]
2024 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 12402
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken, and Marc Wichern. “Comparative Analysis of PH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator.” Chemie Ingenieur Technik 96, no. 4 (2024): 528–34. https://doi.org/10.1002/cite.202300188.
ELSA | DOI | WoS
 
[160]
2023 | Konferenz - Poster | ELSA-ID: 11378
Gassenmeier, Veronika, Giovanni Campolongo, and Björn Frahm. Real-Time Monitoring of DCO2 in Addition to DO, n.d.
ELSA
 
[159]
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann, and Björn Frahm. A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development. DECHEMA e.V., n.d.
ELSA
 
[158]
2023 | Konferenz - Poster | ELSA-ID: 11382 | OA
Gassenmeier, Veronika, Fabian Kuhfuß, Sahar Deppe, George Ifrim, Tanja Hernández Rodriguez, and Björn Frahm. View on a Mechanistic Model of Chlorella Vulgaris in Shake Flasks, n.d.
ELSA | Download (ext.)
 
[157]
2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm, and Björn Frahm. Model-Assisted Design Strategies for Bioprocesses – Advanced Statistical Methods in Industrial Upstream Cell Culture. DECHEMA e.V., 2023.
ELSA
 
[156]
2023 | Konferenzband - Beitrag | ELSA-ID: 11384 | OA
Müller, Carolin, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. Microbial Spoilage in Vegan Foods. Proceedings of the 10th International Congress of Food Technologists, Biotechnologists and Nutritionists: Smart Food for a Healthy Planet and Human Prosperity. Croatian Society of Food Technologists, Biotechnologists and Nutritionists, Zagreb, Croatia, Editors: Draženka Komes, Sanja Vidaček Filipec and Bojana Voučko, 2023.
ELSA | Download (ext.)
 
[155]
2023 | Konferenz - Poster | ELSA-ID: 11487 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm, and Miriam Pein-Hackelbusch. Comparison of Preprocessing Methods of Dielectric Spectroscopy  Data and the Effects on Linear Regression . DECHEMA e.V., n.d.
ELSA | Download (ext.)
 
[154]
2023 | Konferenz - Poster | ELSA-ID: 10201 | OA
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann, and Björn Frahm. A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development, 2023.
ELSA | Download (ext.)
 
[153]
2023 | Konferenz - Vortrag | ELSA-ID: 11109
Blome, André, Mario Luttmann, Mario Jekle, Björn Frahm, and Ulrich Müller. Untersuchung der räumlichen Verteilung von viskoelastischen Kenngrößen während der Weizenteigbereitung, 2023.
ELSA
 
[152]
2023 | Konferenz - Poster | ELSA-ID: 11110
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, 2023.
ELSA
 
[151]
2023 | Konferenz - Poster | ELSA-ID: 12483
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, 2023.
ELSA
 
[150]
2023 | Konferenz - Poster | ELSA-ID: 12485
Luttmann, Mario, André Blome, Mario Jekle, Björn Frahm, and Ulrich Müller. Teig 4.0 - Promotionsthemen, 2023.
ELSA
 
[149]
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm, and Miriam Pein-Hackelbusch. Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities. Edited by Jürgen Jasperneite, Lukasz Wisniewski, Kim Fung Man, and Institute of Electrical and Electronics Engineers . 2023 IEEE 21st International Conference on Industrial Informatics (INDIN). [Piscataway, NJ]: IEEE, 2023. https://doi.org/10.1109/INDIN51400.2023.10218012.
ELSA | DOI | Download (ext.)
 
[148]
2023 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11385
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken, and Marc Wichern. “Validation and Uncertainty Assessment of a Software‐Integrated Workflow for PH Calculations.” Chemie Ingenieur Technik 95, no. 12 (2023): 1960–69. https://doi.org/10.1002/cite.202300082.
ELSA | DOI | WoS
 
[147]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11377
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann, and Björn Frahm. “Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.” Processes 10, no. 5 (2022). https://doi.org/10.3390/pr10050883.
ELSA | DOI
 
[146]
2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann, and Björn Frahm. A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development, n.d.
ELSA
 
[145]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Gassenmeier, Veronika, Sahar Deppe, Tanja Hernández Rodriguez, Fabian Kuhfuß, André Moser, Volker C. Hass, Kim B. Kuchemüller, et al. “Model-Assisted DoE Applied to Microalgae Processes, Current Research in Biotechnology.” Current Research in Biotechnology 4 (2022): 102–19. https://doi.org/10.1016/j.crbiot.2022.01.005.
ELSA | DOI
 
[144]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
Kuhfuß, Fabian, Veronika Gassenmeier, Sahar Deppe, George Adrian Ifrim, Tanja Hernández Rodriguez, and Björn Frahm. “View on a Mechanistic Model of Chlorella Vulgaris in Incubated Shake Flasks.” Bioprocess and Biosystems Engineering 45 (2022): 15–30. https://doi.org/10.1007/s00449-021-02627-2.
ELSA | DOI
 
[143]
2022 | Datenpublikation | ELSA-ID: 10190
Gassenmeier, Veronika, and Björn Frahm. Real-Time Monitoring of DCO2 in Addition to DO. assets-labs, 2022.
ELSA | Dateien verfügbar
 
[142]
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann, and Björn Frahm. “Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.” In Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, edited by Ralf Pörtner and Johannes Möller, special issue:21–48. Processes : Open Access Journal. Basel: MDPI, 2022. https://doi.org/10.3390/pr10050883.
ELSA | DOI
 
[141]
2022 | Konferenzband - Beitrag | ELSA-ID: 10195
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Process Optimisation in the Field of Wheat Dough Processing Using Real-Time Recording of Quality-Relevant Characteristics in Raw Materials, Intermediates and Final Products. Proceedings of the 33rd VH Yeast Conference 2022: Advances in Applied Research & Industrial Production of Baker’s Yeast, “100th Anniversary of VH Berlin & Yeast(s) as an Alternative Protein Source.” Versuchsanstalt der Hefeindustrie e.V., 2022.
ELSA
 
[140]
2022 | Konferenz - Vortrag | ELSA-ID: 10196
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Process Optimisation in the Field of Wheat Dough Processing Using Real-Time Recording of Quality-Relevant Characteristics in Raw Materials, Intermediates and Final Products, 2022.
ELSA
 
[139]
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. Model Assisted Design Strategies for Bioprocesses – Advanced Statistical Methods in Industrial Upstream Cell Culture. ACHEMA 2022, 2022.
ELSA
 
[138]
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez, Tanja, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm, and Björn Frahm. A Systematic, Model-Based Approach for Decision Making in Upstream Development – Considerations Regarding Clone Selection and Cell Expansion, n.d.
ELSA
 
[137]
2022 | Konferenz - Poster | ELSA-ID: 10199 | OA
Müller, Carolin, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. Microbial Spoilage in Vegan Foods. PBN 2022 Congress, 2022.
ELSA | Download (ext.)
 
[136]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11376
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm, and Björn Frahm. “Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection—A Simulation Study.” Processes 9, no. 6 (2021). https://doi.org/10.3390/pr9060964.
ELSA | DOI
 
[135]
2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez, Tanja, and Björn Frahm. Model-Based Methods in Bioprocess Technology - Bioprocess Modeling, Simulation and Prediction, 2021.
ELSA
 
[134]
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser, André, Johannes Möller, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, Björn Frahm, Ralf Pörtner, and Volker C. Hass. Model-Assisted Design of Experiments - Concept, Software and Applications, 2021.
ELSA
 
[133]
2021 | Lexikoneintrag | ELSA-ID: 7939
Wirtanen, Gun, Jarmo Alarinta, Björn Frahm, and Sylvia Fasse. “Bovine Colostrum for Human Consumption.” In MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science, 2021.
ELSA
 
[132]
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm, and Björn Frahm. “Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection – a Simulation Study.” In Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, special issue:49–74. Processes : Open Access Journal . Basel: MDPI, 2021. https://doi.org/10.3390/pr9060964.
ELSA | DOI
 
[131]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. “Dynamic Parameter Estimation and Prediction over Consecutive Scales, Based on Moving Horizon Estimation - Applied to an Industrial Cell Culture Seed Train.” Bioprocess and Biosystems Engineering 44, no. 4 (2021): 793–808. https://doi.org/10.1007/s00449-020-02488-1 .
ELSA | DOI
 
[130]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Moser, André, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Björn Frahm, Ralf Pörtner, Volker C. Hass, and Johannes Möller. “Model-Assisted DoE Software: Optimization of Growth and Biocatalysis in Saccharomyces Cerevisiae Bioprocesses.” Bioprocess and Biosystems Engineering 44, no. 4 (2021): 683–700. https://doi.org/10.1007/s00449-020-02478-3.
ELSA | DOI
 
[129]
2021 | Konferenz - Vortrag | ELSA-ID: 8078
Blome, André, Mario Luttmann, Björn Frahm, and Ulrich Müller. Messtechnikkonzepte Für Die Erfassung von Qualitätsrelevanten Parametern Und Merkmalen Bei Der Weizenteigverarbeitung. Seminar Life Science Technologies 2021-04-28, 2021.
ELSA
 
[128]
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez, Tanja, and Björn Frahm. “Digital Seed Train Twins and Statistical Methods.” In Digital Twins Tools and Concepts for Smart Biomanufacturing, edited by Christoph Herwig, Ralf Pörtner, and Johannes Möller, 176:97–131. Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer, 2021. https://doi.org/10.1007/10_2020_137.
ELSA | DOI
 
[127]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7981
Fasse, Sylvia, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. “Bovine Colostrum for Human Consumption - Improving Microbial Quality and Maintaining Bioactive Characteristics through Processing.” Dairy 2, no. 4 (2021): 556–75. https://doi.org/10.3390/dairy2040044.
ELSA | DOI | WoS
 
[126]
2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim, and Björn Frahm. Modeling of Chlorella Vulgaris in Shake Flasks with Respect to Light Intensity and Light Duration, 2020.
ELSA
 
[125]
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes, 2020.
ELSA
 
[124]
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez, Tanja, Björn Frahm, and Christoph Posch. Integration of Prior Knowledge and Digital Tools for Uncertainty-Based Decision Support, 2020.
ELSA
 
[123]
2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim, and Björn Frahm. Modeling of Chlorella Vulgaris Algae in Shake Flasks with Respect to Light Intensity and Light Duration. Chemie Ingenieur Technik, Tagungsband Zur 10. ProcessNet-Jahrestagung Und 34. DECHEMA-Jahrestagung Der Biotechnologen 2020. Vol. No. 9. Volume 92. Wiley, 2020. https://doi.org/10.1002/cite.202055235.
ELSA | DOI
 
[122]
2020 | Konferenzband - Beitrag | ELSA-ID: 7938
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes. Chemie Ingenieur Technik, Tagungsband Zur 10. ProcessNet-Jahrestagung Und 34. DECHEMA-Jahrestagung Der Biotechnologen 2020. Vol. No. 9. Volume 92. Wiley, 2020. https://doi.org/10.1002/cite.202055234.
ELSA | DOI
 
[121]
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner, and Björn Frahm. Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach. BMC Proceedings. Vol. 14. BioMed Central, 2020. https://doi.org/10.1186/s12919-020-00188-y.
ELSA | Dateien verfügbar | DOI
 
[120]
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß, F., M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, S. Deppe, George Adrian Ifrim, and Björn Frahm. Modeling of Chlorella Vulgaris in Shake Flasks with Respect to Light Intensity and Light Duration, 2020.
ELSA
 
[119]
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe, S., F. Kuhfuß, M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, J. Möller, et al. Model-Assisted Design of Experiments for Algae Cultivation, 2020.
ELSA
 
[118]
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, and Björn Frahm. Modeling of Microalgae in an Air-Lift Photobioreactor for Biomass Production, 2020.
ELSA
 
[117]
2020 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2392
Möller, Johannes, Tanja Hernández Rodríguez, Jan Müller, Lukas Arndt, Kim B. Kuchemüller, Björn Frahm, Regine Eibl, Dieter Eibl, and Ralf Pörtner. “Model Uncertainty-Based Evaluation of Process Strategies during Scale-up of Biopharmaceutical Processes.” Computers & Chemical Engineering 134 (2020): 1–13. https://doi.org/10.1016/j.compchemeng.2019.106693.
ELSA | DOI
 
[116]
2020 | Sammelwerk - Beitrag | ELSA-ID: 2397
Hernández Rodríguez, Tanja, and Björn Frahm. “Design, Optimization and Adaptive Control of Cell Culture Seed Trains.” In Animal Cell Biotechnology - Methods and Protocols, edited by Ralf Pörtner, 2095:251–67. Methods in Molecular Biology. Berlin, Heidelberg, New York: Springer, 2020. https://doi.org/10.1007/978-1-0716-0191-4_14.
ELSA | DOI
 
[115]
2020 | Sammelwerk - Beitrag | ELSA-ID: 2399
Deppe, S., Björn Frahm, V. C. Hass, T. Hernández Rodríguez, K. B. Kuchemüller, J. Möller, and R. Pörtner. “Estimation of Process Model Parameters.” In Animal Cell Biotechnology: Methods and Protocols, edited by Ralf Pörtner, 2095:213–34. Methods in Molecular Biology. Berlin ; Heidelberg ; New York: Springer, 2020. https://doi.org/10.1007/978-1-0716-0191-4_12.
ELSA | DOI
 
[114]
2019 | Konferenz - Vortrag | ELSA-ID: 7928
Frahm, Björn. Scale-up of Stirred Vessels, 2019.
ELSA
 
[113]
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller, J., J. Müller, Tanja Hernández Rodriguez, K. B. Kuchemüller, L. Arndt, Björn Frahm, R. Eibl, D. Eibl, and R. Pörtner. Workflow for Model-Assisted Design and Scale-up of Biopharmaceutical Production Processes, 2019.
ELSA
 
[112]
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller, J., K. B. Kuchemüller, A. Moser, V. C. Hass, Tanja Hernández Rodriguez, S. Deppe, Björn Frahm, and R. Pörtner. Model-Assisted Design of Experiments, 2019.
ELSA
 
[111]
2019 | Konferenz - Vortrag | ELSA-ID: 2958
Ifrim, George Adrian, M. Titica, S. Deppe, Björn Frahm, M. Barbu, and S. Caraman. Novel Control Strategy for Microalgae in Photobioreactor, 2019.
ELSA
 
[110]
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner, and Björn Frahm. Predicting Industrial Scale Cell Culture Seed Trains – Considerations of Input Uncertainty, New Process Data and Prognostic Intervals Using a Bayesian Approach and Sequential Bayesian Updating, 2019.
ELSA
 
[109]
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner, and Björn Frahm. Predicting Industrial Scale Cell Culture Seed Trains – Considerations of Input Uncertainty, New Process Data and Prognostic Intervals Using a Bayesian Approach and Sequential Bayesian Updating, 2019.
ELSA
 
[108]
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, S. Deppe, George Adrian Ifrim, A. Moser, V. C. Hass, Björn Frahm, and R. Pörtner. Model-Assisted Design of Experiments – Software Toolbox, 2019.
ELSA
 
[107]
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe, S., Tanja Hernández Rodriguez, Veronika Gassenmeier, M. Tölle, F. Kuhfuß, J. Möller, K. B. Kuchemüller, et al. Model-Assisted Design of Experiments for Algae Cultivation, 2019.
ELSA
 
[106]
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, and Björn Frahm. Modeling of Microalgae in an Air-Lift Photobioreactor for Biomass Production, 2019.
ELSA
 
[105]
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner, and Björn Frahm. Predicting Industrial Scale Cell Culture Seed Trains – Considerations of Input Uncertainty, New Process Data and Prognostic Intervals Using a Bayesian Approach and Sequential Bayesian Updating, 2019.
ELSA
 
[104]
2019 | Konferenz - Poster | ELSA-ID: 3006
Ifrim, George Adrian, M. Titica, S. Deppe, Björn Frahm, M. Barbu, and S. Caraman. Multivariable Control Strategy for the Photosynthetic Cultures of Microalgae, 2019.
ELSA
 
[103]
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 | OA
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner, and Björn Frahm. “Predicting Industrial‐scale Cell Culture Seed Trains–A Bayesian Framework for Model Fitting and Parameter Estimation, Dealing with Uncertainty in Measurements and Model Parameters, Applied to a Nonlinear Kinetic Cell Culture Model, Using an MCMC Method.” Biotechnology and Bioengineering 116, no. 11 (2019): 2944–59. https://doi.org/10.1002/bit.27125.
ELSA | DOI | Download (ext.)
 
[102]
2019 | Konferenzband - Beitrag | ELSA-ID: 2400
Ifrim, George Adrian, Mariana Titica, Sahar Deppe, Björn Frahm, Marian Barbu, and Sergiu Caraman. Multivariable Control Strategy for the Photosynthetic Cultures of Microalgae. 2019 23rd International Conference on System Theory, Control and Computing (ICSTCC). IEEE, 2019. https://doi.org/10.1109/icstcc.2019.8886109.
ELSA | DOI
 
[101]
2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez, Tanja, Björn Frahm, Christoph Posch, Julia Schmutzhard, and Josef Stettner. A Model-Assisted Approach for Design, Optimization and Control of Bioprocesses – a Software Tool for Seed Train Simulation and Optimization, 2018.
ELSA
 
[100]
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez, Tanja, Susan Krull, Volker C. Hass, Johannes Möller, Ralf Pörtner, and Björn Frahm. Model-Assisted Cell Culture Control – Unstructured, Unsegregated Models as a Key Element for Adaptive Seed Train and Fed-Batch Optimization. BMC Proceedings. Vol. 112. BioMed Central, 2018. https://doi.org/10.1186/s12919-018-0097-x.
ELSA | Dateien verfügbar | DOI
 
[99]
2018 | Konferenz - Vortrag | ELSA-ID: 2955
Pörtner, R., J. Möller, Björn Frahm, and V. C. Hass. Model-Assisted Design of Process Strategies for Cell Culture Processes, 2018.
ELSA
 
[98]
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller, J., K. B. Kuchemüller, F. Freiberger, P. Levermann, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass, and R. Pörtner. Model-Assisted Design and Optimization of Process Strategies, 2018.
ELSA
 
[97]
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez, Tanja, J. Möller, K. B. Kuchemüller, F. Freiberger, P. Levermann, V. C. Hass, Björn Frahm, and R. Pörtner. Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses, 2018.
ELSA
 
[96]
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 | OA
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass, and R. Pörtner. “Model-Assisted Design of Process Strategies for Cell Culture Processes.” American Pharmaceutical Review 3 (2018): 39–41.
ELSA | Download (ext.)
 
[95]
2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez, Tanja, S. Kern, O. Platas Barradas, R. Pörtner, and Björn Frahm. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren, 2017.
ELSA
 
[94]
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner, R., J. Möller, Tanja Hernández Rodriguez, Björn Frahm, and V. C. Hass. Model-Assisted Design and Optimization of Biotechnological Processes, 2017.
ELSA
 
[93]
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez, Tanja, K. S. Koopmann, J. Klaes, S. Kern, O. Platas Barradas, R. Pörtner, and Björn Frahm. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren, 2017.
ELSA
 
[92]
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez, Tanja, K. S. Koopmann, R. Pörtner, and Björn Frahm. Influence of Parameter Accuracies in Cell Culture Seed Train Simulations, 2017.
ELSA
 
[91]
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, J. Möller, R. Pörtner, and Björn Frahm. Model-Based Cell Culture Control – Unstructured, Unsegregated Models as a Key Element for Adaptive Seed Train and Fed-Batch Optimization, 2017.
ELSA
 
[90]
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, R. Pörtner, and Björn Frahm. Model-Based Cell Culture Control – Unstructured, Unsegregated Models as a Key Element for Adaptive Seed Train and Fed-Batch Optimization, 2017.
ELSA
 
[89]
2016 | Konferenz - Poster | ELSA-ID: 2991
Beshay, U., Sebastian Feldt, B. Schwarze, P. Wefing, T. Hahne, J. Moschinski, C. Müller, et al. DMA Photobioreactor System – Cultivation at Low Shear Stress and Optional Membrane Aeration, 2016.
ELSA
 
[88]
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez, Tanja, S. Vörtler, S. Kern, O. Platas Barradas, R. Pörtner, and Björn Frahm. A Software Tool for Biopharmaceutical Seed Train Design and Optimization, 2016.
ELSA
 
[87]
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann, K. S., Tanja Hernández Rodriguez, S. Vörtler, U. Beshay, J. Möller, R. Pörtner, and Björn Frahm. Simulation of Cell Culture Seed Trains – Investigation of the Influence of Parameter Inaccuracies, 2016.
ELSA
 
[86]
2016 | Sammelwerk - Beitrag | ELSA-ID: 2395
Pörtner, R., O. Platas Barradas, Björn Frahm, and V.C. Hass. “Advanced Process and Control Strategies for Bioreactors.” In Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls, 463–93. Amsterdam: Elsevier, 2016. https://doi.org/10.1016/b978-0-444-63663-8.00016-1.
ELSA | DOI
 
[85]
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner, and Björn Frahm. Considerations for Cell Passaging in Cell Culture Seed Trains. BMC Proceedings / BioMed Central. Vol. 9. BioMed Central, 2015. https://doi.org/10.1186/1753-6561-9-s9-p43.
ELSA | DOI | Download (ext.)
 
[84]
2015 | Konferenzband - Beitrag | ELSA-ID: 2820 | OA
Kern, Simon, Oscar Platas Barradas, Martin Schaletzky, Volker Sandig, Björn Frahm, and Ralf Pörtner. Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale. BMC Proceedings / BioMed Central. Vol. 9. BioMed Central, 2015. https://doi.org/10.1186/1753-6561-9-s9-p44.
ELSA | DOI | Download (ext.)
 
[83]
2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm, Björn, R. Pörtner, S. Kern, and Tanja Hernández Rodriguez. Seed Train Design and Optimization for Animal Cell Suspension Culture, 2015.
ELSA | Dateien verfügbar
 
[82]
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm, Björn, Tanja Hernández Rodriguez, S. Kern, K. S. Koopmann, U. Beshay, O. Platas-Barradas, and R. Pörtner. Seed Train Design and Optimization for Animal Cell Suspension Culture, 2015.
ELSA
 
[81]
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. Considerations for Cell Passaging in Cell Culture Seed Trains, 2015.
ELSA
 
[80]
2015 | Konferenz - Poster | ELSA-ID: 2986
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale, 2015.
ELSA
 
[79]
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. A Software Tool for Biopharmaceutical Seed Train Design and Optimization, 2015.
ELSA
 
[78]
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. Considerations for Cell Passaging in Cell Culture Seed Trains, 2015.
ELSA
 
[77]
2015 | Konferenz - Poster | ELSA-ID: 2990
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale, 2015.
ELSA
 
[76]
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2389
Kern, Simon, Oscar Platas-Barradas, Ralf Pörtner, and Björn Frahm. “Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale.” Cytotechnology 68, no. 4 (2015): 1019–32. https://doi.org/10.1007/s10616-015-9858-9.
ELSA | DOI | Download (ext.)
 
[75]
2014 | Patent | ELSA-ID: 2878
Frahm, Björn, and Uwe Meier. “Beleuchtung von Disposable Bioreaktoren,” 2014.
ELSA
 
[74]
2014 | Konferenz - Poster | ELSA-ID: 2984
Drews, F., G. Drews, C. Folz, G. Platz, Thomas Gassenmeier, M. Kramer, C. Hundeiker, B. Schwarze, and Björn Frahm. Herstellung von Paramylon mit Euglena gracilis im disposable Bag mit LED-Beleuchtung direkt auf dessen Oberfläche, 2014.
ELSA
 
[73]
2014 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2388
Hahne, T., B. Schwarze, M. Kramer, and Björn Frahm. “Disposable Algae Cultivation for High-Value Products Using All around LED-Illumination Directly on the Bags.” Journal of Algal Biomass Utilization 5, no. 2 (2014): 66–73.
ELSA
 
[72]
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner, and Björn Frahm. Seed Train Optimization for Suspension Cell Culture. BMC Proceedings / BioMed Central . Vol. 7. BioMed Central , 2013. https://doi.org/10.1186/1753-6561-7-s6-p9.
ELSA | DOI | Download (ext.)
 
[71]
2013 | Konferenzband - Beitrag | ELSA-ID: 2818 | OA
Kern, Simon, Oscar Platas, Martin Schaletzky, Volker Sandig, Björn Frahm, and Ralf Pörtner. Model-Based Design of the First Steps of a Seed Train for Cell Culture Processes. BMC Proceedings / BioMed Central . Vol. 7. BioMed Central, 2013. https://doi.org/10.1186/1753-6561-7-s6-p11.
ELSA | DOI | Download (ext.)
 
[70]
2013 | Konferenz - Poster | ELSA-ID: 2980
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Modellgestützte Auslegung der ersten Schritte eines Seed-Trains für Zellkulturprozesse, 2013.
ELSA
 
[69]
2013 | Konferenz - Poster | ELSA-ID: 2981
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Model-Based Design of the First Steps of a Seed Train for Cell Culture Processes, 2013.
ELSA
 
[68]
2013 | Konferenz - Poster | ELSA-ID: 2982
Hahne, T., B. Schwarze, J. Moschinski, A. Kuttig, M. Kramer, and Björn Frahm. Disposable Algenkultivierung für hochpreisige Produkte mittels LED-Rundumbeleuchtung direkt auf den Bags, 2013.
ELSA
 
[67]
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. Seed Train Optimization for Suspension Cell Culture, 2013.
ELSA
 
[66]
2013 | Sammelwerk - Beitrag | ELSA-ID: 10214
Frahm, Björn. “Seed Train Optimization for Cell Culture.” In Animal Cell Biotechnology - Methods and Protocols, edited by Ralf Pörtner, 3rd ed., 1104:355–67. Methods in Molecular Biology. Totowa, NJ: Humana Press, 2013. https://doi.org/10.1007/978-1-62703-733-4_22.
ELSA | DOI
 
[65]
2012 | Konferenzband - Beitrag | ELSA-ID: 2816 | OA
Frahm, Björn, and H. Brod. Improving Cell Culture Bioreactor Performance for Sensitive Cell Lines by Dynamic Membrane Aeration (DMA). Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. Vol. 5. ESACT Proceedings. Dordrecht: Springer, 2012. https://doi.org/10.1007/978-94-007-0884-6_56.
ELSA | DOI | Download (ext.)
 
[64]
2012 | Patent | ELSA-ID: 2877
Brod, Helmut, and Björn Frahm. “Photobioreaktor Mit Rotatorisch Oszillierenden Lichtquellen,” 2012.
ELSA
 
[63]
2012 | Konferenz - Vortrag | ELSA-ID: 2918
Van Hecke, W., D. Haltrich, Björn Frahm, H. Brod, and R. Ludwig. Modelling and Upscaling of a Biocatalytic Cascade Oxidation in a Dynamic Membrane Aeration Reactor. Achema 2012. Vogel Business Media, 2012.
ELSA
 
[62]
2012 | Konferenz - Poster | ELSA-ID: 2973
Marzougui, R., R. Pörtner, and Björn Frahm. Optimierung des Seed trains von Suspensions-Zellkulturen, 2012.
ELSA
 
[61]
2011 | Patent | ELSA-ID: 2876
Brod, Helmut, Björn Frahm, Marc Jenne, Jörg Kauling, Franz Schmitt, and Juri Seletzky. “Flüssigkeitsbegaser,” 2011.
ELSA
 
[60]
2011 | Konferenz - Poster | ELSA-ID: 2972
Van Hecke, W., D. Haltrich, Björn Frahm, H. Brod, and R. Ludwig. Modelling and Upscaling of a Biocatalytic Cascade Oxidation in a Dynamic Membrane Aeration Reactor, 2011.
ELSA
 
[59]
2011 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2350
Van Hecke, Wouter, Dietmar Haltrich, Björn Frahm, Helmut Brod, Jo Dewulf, Herman Van Langenhove, and Roland Ludwig. “A Biocatalytic Cascade Reaction Sensitive to the Gas–Liquid Interface: Modeling and Upscaling in a Dynamic Membrane Aeration Reactor.” Journal of Molecular Catalysis B: Enzymatic 68, no. 2 (2011): 154–61. https://doi.org/10.1016/j.molcatb.2010.10.004.
ELSA | DOI | Download (ext.)
 
[58]
2010 | Konferenzband - Beitrag | ELSA-ID: 2815
Dercks, B., Björn Frahm, M. Grünewald, E. Kenig, A. Lautenschleger, A. Gorak, P. Schmidt, D. Sudhoff, S. Ressler, and R. Zecirovic. Intensified Absorption and Distillation Devices for Modular Chemical Production Processes. Proceedings 19th International Congress of Chemical and Process Engineering. Czech Society of Chemical Engineering, 2010.
ELSA
 
[57]
2010 | Patent | ELSA-ID: 2873
Brod, Helmut, Björn Frahm, and Jörg Kauling. “Verfahren Zur Reduzierung von Ablagerungen Bei Der Kultivierung von Organismen,” 2010.
ELSA
 
[56]
2010 | Patent | ELSA-ID: 2874
Brod, Helmut, Björn Frahm, Marc Jenne, and Jörg Kauling. “Bioreaktor,” 2010.
ELSA
 
[55]
2010 | Patent | ELSA-ID: 2875
Frahm, Björn, Jörg Kauling, Andre Pütz, and Markus Schindler. “Begasungssystem,” 2010.
ELSA
 
[54]
2010 | Konferenz - Vortrag | ELSA-ID: 2892
Frahm, Björn, and Helmut Brod. Cultivation of Sensitive Cell Lines - Improving Bioreactor Performance by Dynamic Membrane Aeration, 2010.
ELSA
 
[53]
2010 | Konferenz - Vortrag | ELSA-ID: 2913
Dercks, B., Björn Frahm, M. Grünewald, E. Kenig, A. Lautenschleger, A. Gorak, P. Schmidt, D. Sudhoff, S. Ressler, and R. Zecirovic. Intensified Absorption and Distillation Devices for Modular Chemical Production Processes, 2010.
ELSA
 
[52]
2009 | Patent | ELSA-ID: 2872
Braun, Arndt, Helmut Brod, Björn Frahm, Marc Jenne, Jörg Kauling, and Stephan Kirchner. “Verfahren Und Vorrichtung Zur Rückhaltung Und Rückführung von Zellen,” 2009.
ELSA
 
[51]
2009 | Konferenz - Vortrag | ELSA-ID: 2912
Frahm, Björn, H. Brod, and U. Langer. Improving Cell Culture Bioreactor Performance by Dynamic Membrane Aeration (DMA), 2009.
ELSA
 
[50]
2009 | Konferenz - Poster | ELSA-ID: 2970
Frahm, Björn, H. Brod, and U. Langer. Improving Cell Culture Bioreactor Performance by Dynamic Membrane Aeration (DMA), 2009.
ELSA
 
[49]
2009 | Konferenz - Poster | ELSA-ID: 2971
Van Hecke, W., H. Van Langenhovve, Björn Frahm, H. Brod, J. Dewulf, D. Haltrich, and R. Ludwig. Upscaling the Biocatalytic Conversion of Lactose to Lactobionic Acid with the Dynamic Membrane Aeration Reactor, 2009.
ELSA
 
[48]
2009 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2349 | OA
Frahm, Björn, Helmut Brod, and Uwe Langer. “Improving Bioreactor Cultivation Conditions for Sensitive Cell Lines by Dynamic Membrane Aeration.” Cytotechnology 59, no. 1 (2009): 17–30. https://doi.org/10.1007/s10616-009-9189-9.
ELSA | DOI | Download (ext.)
 
[47]
2008 | Konferenz - Vortrag | ELSA-ID: 2911
Brod, H., J. Kauling, Björn Frahm, M. Jenne, U. Langer, and B. Bödeker. Pushing the Limits in High-Density Mammalian Cell Fermentation, 2008.
ELSA
 
[46]
2008 | Konferenz - Poster | ELSA-ID: 2968
Frahm, Björn, H. Brod, M. Burnett, U. Langer, and B. Bödeker. High Cell Density Bioreactor Cultivation by Dynamic Membrane Aeration (DMA), 2008.
ELSA
 
[45]
2008 | Konferenz - Poster | ELSA-ID: 2969
Frahm, Björn, and Helmut Brod. High Cell Density Bioreactor Cultivation by Dynamic Membrane Aeration (DMA), 2008.
ELSA
 
[44]
2007 | Konferenzband - Beitrag | ELSA-ID: 2814
Pörtner, Ralf, Björn Frahm, Paul Lane, Axel Munack, Kathrin Kühn, and Volker C. Hass. Optimisation of Time-Space-Yield for Hybridoma Fed-Batch Cultures with an Adaptive Olfo-Controller. Cell Technology for Cell Products. Vol. 3. ESACT Proceedings. Dordrecht: Springer, 2007. https://doi.org/10.1007/978-1-4020-5476-1_84.
ELSA | DOI
 
[43]
2007 | Patent | ELSA-ID: 2870 | OA
Brod, Helmut, Björn Frahm, Jörg Kauling, and Reinhold Rose. “Procedure for Gassing of Liquid for Cell Cultures, Comprises Exchanging of Gas over Immersed Membrane Surfaces and Controlling the Gassing Rate Change of the Gas Concentration and/or Pressure of the Gas or Gas Mixture or Gas Component,” 2007.
ELSA | Download (ext.)
 
[42]
2007 | Patent | ELSA-ID: 2871
Brod, Helmut, Björn Frahm, Jörg Kauling, Martin Poggel, Reinhold Rose, and Sebastian Schmidt. “Verfahren Und Vorrichtung Zur Be- Und Entgasung von Flüssigkeiten, Insbesondere in Der Biotechnologie Und Speziell von Zellkulturen,” 2007.
ELSA
 
[41]
2007 | Konferenz - Vortrag | ELSA-ID: 2909
Brod, Helmut, Björn Frahm, and Jörg Kauling. Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen, 2007.
ELSA
 
[40]
2007 | Konferenz - Vortrag | ELSA-ID: 2910
Brod, Helmut, Björn Frahm, and Jörg Kauling. Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen, 2007.
ELSA
 
[39]
2007 | Konferenz - Poster | ELSA-ID: 2967
Frahm, Björn, S. Kirchner, R. Rose, M. Jenne, J. Kauling, H. Brod, K. Jöris, M. Wischniewski, U. Langer, and B. Bödeker. High Cell Density Bioreactor Cultivation by Dynamic Membrane Aeration (DMA), 2007.
ELSA
 
[38]
2007 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2348
Frahm, Björn, S. Kirchner, J. Kauling, H. Brod, U. Langer, and B. Bödeker. “Dynamische Membranbegasung im Bioreaktor zur Intensivierung der Sauerstoffversorgung empfindlicher Zelllinien.” Chemie Ingenieur Technik 79, no. 7 (2007): 1052–58. https://doi.org/10.1002/cite.200700070.
ELSA | DOI | Download (ext.)
 
[37]
2005 | Konferenzband - Beitrag | ELSA-ID: 2813
Frahm, Björn, and R. Pörtner. Flexible Fed-Batch Process Control of Animal Cells. Animal Cell Technology Meets Genomics. Vol. 2. ESACT Proceedings. Dordrecht: Springer, 2005. https://doi.org/10.1007/1-4020-3103-3_142.
ELSA | DOI
 
[36]
2005 | Konferenz - Vortrag | ELSA-ID: 2907
Pörtner, Ralf, Björn Frahm, P. Lane, and A. Munack. Optimisation of Time-Space-Yield for Hybridoma Fed-Batch Cultures with an Adaptive OLFO-Controller, 2005.
ELSA
 
[35]
2005 | Konferenz - Vortrag | ELSA-ID: 2908
Pörtner, R., Björn Frahm, V. C. Hass, P. Lane, and A. Munack. Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode, 2005.
ELSA
 
[34]
2005 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2347 | OA
Frahm, Björn, Paul Lane, Axel Munack, and Ralf Pörtner. “Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode.” Chemie Ingenieur Technik 77, no. 4 (2005): 429–35. https://doi.org/10.1002/cite.200407094.
ELSA | DOI | Download (ext.)
 
[33]
2004 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2345 | OA
Pörtner, Ralf, Jan-Oliver Schwabe, and Björn Frahm. “Evaluation of Selected Control Strategies for Fed-Batch Cultures of a Hybridoma Cell Line.” Biotechnology and Applied Biochemistry 40 (2004). https://doi.org/10.1042/ba20030168.
ELSA | DOI | Download (ext.)
 
[32]
2003 | Konferenz - Vortrag | ELSA-ID: 7934
Frahm, Björn, and Ralf Pörtner. Fed-Batch-Cultivation of Animal Cells: Model-Based, Adaptive Control in Comparison to Alternative Control Strategies, 2003.
ELSA
 
[31]
2003 | Konferenzband - Beitrag | ELSA-ID: 2435
Frahm, Björn, B. Müller-Landré, G. Wiggers de Almeida, M. Singer, M. Rausch, P. Lane, A. Munack, V. C. Hass, and R. Pörtner. Fed-Batch Cultivation of Animal Cells - a Challenge for Adaptive, Model-Based Control. Edited by Dieter Beckmann and Heiligenstädter Kolloquium (11 : 2002 : Heiligenstadt, Eichsfeld). Technische Systeme Für Biotechnologie Und Umwelt. Heiligenstadt: Inst. für Bioprozess- und Analysenmesstechnik , 2003.
ELSA
 
[30]
2003 | Konferenzband - Beitrag | ELSA-ID: 2436
Kühn, K., Björn Frahm, R. Pörtner, P. Lane, A. Munack, and V. C. Hass. Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells. Edited by European Federation of Chemical Engineering. ECCE - 4th European Congress of Chemical Engineering. Vol. 10. Granada: ECCE4, 2003.
ELSA
 
[29]
2003 | Konferenz - Vortrag | ELSA-ID: 2902
Frahm, Björn, and Ralf Pörtner. Fed-Batch-Kultivierungen tierischer Zellen – eine Herausforderung an eine modellgestützte, adaptive Steuerung, 2003.
ELSA
 
[28]
2003 | Konferenz - Vortrag | ELSA-ID: 2903
Hass, V. C. , K. Kühn, Björn Frahm, R. Pörtner, P. Lane, and A. Munack. Ein strukturiertes Kompartiment-Modell zur Beschreibung der Kultivierung von Hybridomazellen als Teil einer adaptiven, modellgestützten Prozessführung, 2003.
ELSA
 
[27]
2003 | Konferenz - Vortrag | ELSA-ID: 2905
Frahm, Björn, P. Lane, A. Munack, V. C. Hass, and Ralf Pörtner. Fed-Batch-Cultivation of Animal Cells: Model-Based, Adaptive Control in Comparison to Alternative Control Strategies, 2003.
ELSA | Dateien verfügbar
 
[26]
2003 | Konferenz - Vortrag | ELSA-ID: 2906
Pörtner, Ralf, Björn Frahm, P. Lane, V. C. Hass, A. Munack, and H. Märkl. Fed-Batch-Kultivierung tierischer Zellen – eine Herausforderung für eine adaptive, modellgestützte Steuerung, 2003.
ELSA
 
[25]
2003 | Konferenz - Poster | ELSA-ID: 2964
Frahm, Björn, and Ralf Pörtner. CO2-off-Gas Measurement for Animal Cell Culture Processes, 2003.
ELSA
 
[24]
2003 | Konferenz - Poster | ELSA-ID: 2965
Frahm, Björn, and Ralf Pörtner. Flexible Fed-Batch Process Control of Animal Cells, 2003.
ELSA
 
[23]
2003 | Konferenz - Poster | ELSA-ID: 2966
Kühn, K., Björn Frahm, Ralf Pörtner, P. Lane, A. Munack, and V. C. Hass. Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells, 2003.
ELSA
 
[22]
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2343 | OA
Frahm, Björn, V. C. Hass, P. Lane, A. Munack, H. Märkl, and R. Pörtner. “Fed-Batch-Kultivierung tierischer Zellen - Eine Herausforderung zur adaptiven, modellbasierten Steuerung.” Chemie Ingenieur Technik 75, no. 4 (2003): 457–60. https://doi.org/10.1002/cite.200390093.
ELSA | DOI | Download (ext.)
 
[21]
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2344 | OA
Frahm, Björn, P. Lane, H. Märkl, and R. Pörtner. “Improvement of a Mammalian Cell Culture Process by Adaptive, Model-Based Dialysis Fed-Batch Cultivation and Suppression of Apoptosis.” Bioprocess and Biosystems Engineering 26, no. 1 (2003): 1–10. https://doi.org/10.1007/s00449-003-0335-z.
ELSA | DOI | Download (ext.)
 
[20]
2003 | Dissertation | ELSA-ID: 2393
Frahm, Björn. Adaptive, modellgestützte Prozessführung von Suspensionskulturen tierischer Zellen. Norderstedt: Books on Demand GmbH, 2003.
ELSA
 
[19]
2002 | Konferenzband - Beitrag | ELSA-ID: 2431
Frahm, Björn, and Ralf Pörtner. Messung Und Simulation Des Kohlendioxidausstoßes von Zellkulturprozessen. Edited by Heiner Kaden and Forum Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung Biotechnologischer Prozesse (2001 : Waldheim). Biosystemtechnik: Innovative Biosystemtechnik - Sensorik, Aktorik Und Auswertung Biotechnologischer Prozesse. Meinsberg : Kurt-Schwabe-Inst. , 2002.
ELSA
 
[18]
2002 | Konferenz - Vortrag | ELSA-ID: 2897
Frahm, Björn, and Ralf Pörtner. Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen, 2002.
ELSA
 
[17]
2002 | Konferenz - Vortrag | ELSA-ID: 2898
Frahm, Björn, and Ralf Pörtner. Adaptive, Model-Based Control by the OLFO-Controller for the Fed-Batch Cultivation of Animal Cells, 2002.
ELSA
 
[16]
2002 | Konferenz - Vortrag | ELSA-ID: 2899
Frahm, Björn, and Ralf Pörtner. Adaptive, Model-Based Control by the OLFO-Controller for the Fed-Batch Cultivation of Animal Cells, 2002.
ELSA
 
[15]
2002 | Konferenz - Vortrag | ELSA-ID: 2900
Frahm, Björn, B. Müller-Landré, G. Wiggers de Almeida, M. Singer, M. Rausch, P. Lane, A. Munack, V. C. Hass, and R. Pörtner. Fed-Batch Cultivation of Animal Cells - a Challenge for Adaptive, Model-Based Control, 2002.
ELSA
 
[14]
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2340 | OA
Frahm, Björn, H.-C. Blank, P. Cornand, W. Oelßner, U. Guth, P. Lane, A. Munack, K. Johannsen, and R. Pörtner. “Determination of Dissolved CO2 Concentration and CO2 Production Rate of Mammalian Cell Suspension Culture Based on Off-Gas Measurement.” Journal of Biotechnology 99, no. 2 (2002): 133–48. https://doi.org/10.1016/S0168-1656(02)00180-3.
ELSA | DOI | Download (ext.)
 
[13]
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2341 | OA
Frahm, Björn, P. Lane, H. Atzert, A. Munack, M. Hoffmann, V. C. Hass, and R. Pörtner. “Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Effective Fed-Batch Cultivation of Hybridoma Cells.” Biotechnology Progress 18, no. 5 (2002): 1095–1103. https://doi.org/10.1021/bp020035y.
ELSA | DOI | Download (ext.)
 
[12]
2002 | Zeitschriftenaufsatz | ELSA-ID: 2342
Frahm, Björn, and R. Pörtner. “Reaktor-Abgasmessungen bei Zellkulturen.” BIOforum 4 (2002): 179–80.
ELSA
 
[11]
2001 | Konferenz - Vortrag | ELSA-ID: 7933
Frahm, Björn, and Ralf Pörtner. Messung Und Simulation Des Kohlendioxidausstoßes von Zellkulturprozessen, 2001.
ELSA
 
[10]
2001 | Konferenzband - Beitrag | ELSA-ID: 2427
Frahm, Björn, H. Atzert, P. Lane, M. Hoffmann, V. C. Hass, A. Munack, and Ralf Pörtner. Development of an Automated, Adaptive Model-Based Control for the Effective Cultivation of Hybridoma Cells. Animal Cell Technology: From Target to Market. Vol. 1. ESACT Proceedings. Dordrecht: Springer, 2001. https://doi.org/10.1007/978-94-010-0369-8_107.
ELSA | DOI
 
[9]
2001 | Konferenz - Poster | ELSA-ID: 2429
Hass, V. C., P. Lane, M. Hoffmann, Björn Frahm, J.-O. Schwabe, R. Pörtner, and A. Munack. Model-Based Control of Hybridoma Cell Cultures, 2001.
ELSA
 
[8]
2001 | Konferenz - Vortrag | ELSA-ID: 2894
Hoffmann, M., V. C. Hass, Björn Frahm, J.-O. Schwabe, R. Pörtner, P. Lane, and A. Munack. Untersuchung verschiedener mathematischer Modelle in Hinblick auf ihre Eignung für die adaptive Prozessführung von Hybridoma Zellkulturen, 2001.
ELSA
 
[7]
2001 | Konferenz - Vortrag | ELSA-ID: 2895
Frahm, Björn, and R. Pörtner. Arbeitsschwerpunkte TUHH, Bioprozess- und Bioverfahrenstechnik, Arbeitsgruppe Zellkulturtechnik, 2001.
ELSA
 
[6]
2001 | Konferenz - Poster | ELSA-ID: 2960
Frahm, Björn, H. Atzert, J.-O. Schwabe, P. Lane, A. Munack, M. Hoffmann, V. C. Hass, and R. Pörtner. Adaptive Modellgestützte Steuerung von Zellkulturprozessen, 2001.
ELSA
 
[5]
2001 | Konferenz - Poster | ELSA-ID: 2961
Lane, P., Björn Frahm, H. Atzert, J.-O. Schwabe, M. Hoffmann, V. C. Hass, and R. Pörtner. Design of Feeding Strategies for Fed-Batch Cultures of Animal Cells by the Method of Inequalities, 2001.
ELSA
 
[4]
2001 | Konferenz - Poster | ELSA-ID: 2962
Frahm, Björn, H. Atzert, P. Lane, M. Hoffmann, V. C. Hass, A. Munack, and R. Pörtner. Development of an Automated, Model-Based, Adaptive Control for the Effective Cultivation of Hybridoma Cells, 2001.
ELSA
 
[3]
2001 | Konferenzband - Beitrag | ELSA-ID: 2963 | OA
Hass, V.C., P. Lane, M. Hoffmann, Björn Frahm, J.-O. Schwabe, R. Pörtner, and A. Munack. Model-Based Control of Hybridoma Cell Cultures. Edited by Published for the International Federation of Automatic Control by Pergamon . Computer Applications in Biotechnology, 2001: Modelling, Monitoring and Control of Biotechnological Processes. Vol. 34.   IFAC Proceedings Volumes / IFAC, International Federation of Automatic Control. Oxford: ScienceDirect, 2001. https://doi.org/10.1016/S1474-6670(17)34240-4.
ELSA | DOI | Download (ext.)
 
[2]
2000 | Konferenz - Vortrag | ELSA-ID: 2893
Anderelei, T., Björn Frahm, and J. Büchs. Online-Bestimmung der Sauerstofftransferrate (OTR) und der Kohlendioxidtransferrate (CTR) in geschüttelten Bioreaktoren, 2000.
ELSA
 
[1]
2000 | Konferenz - Poster | ELSA-ID: 2959
Hoffmann, M., Björn Frahm, J.-O. Schwabe, P. Lane, R. Pörtner, V. C. Hass, and A. Munack. Modellgestützte Prozessführung Für Hybridoma-Kulturen Mit Hilfe Des Open-Loop-Feedback-Optimal (OLFO)- Algorithmus, 2000.
ELSA
 
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[168]
2024 | Konferenz - Vortrag | ELSA-ID: 12021
Segermann, Jan, Mario Luttmann, André Blome, Sebastian Feldt, Sujee Sivanesan, Christoph-Alexander Holst, Volker Lohweg, Björn Frahm, and Ulrich Müller. Die Rolle von ML-Modellen in der Lebensmitteltechnologie: Eine Fallstudie zur Sauerteigfermentation mit NIR-Spektroskopie, 2024.
ELSA
 
[167]
2024 | Konferenz - Vortrag | ELSA-ID: 12022
Luttmann, Mario, André Blome, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Erkenntnisse zur Nutzung von Photogrammmetrie für die Untersuchung des Bräunungsverhaltens von Weizenbrötchen, 2024.
ELSA
 
[166]
2024 | Konferenz - Poster | ELSA-ID: 12395
Müller, Carolin, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. Investigation of Microbial Spoilage in Vegan Foods, 2024.
ELSA
 
[165]
2024 | Konferenz - Poster | ELSA-ID: 12396
Gassenmeier, Veronika, Giovanni Campolongo, and Björn Frahm. Dissolved Carbon Dioxide in Addition to Dissolved Oxygen for In-Situ Monitoring of Hybridoma Cell Culture, 2024.
ELSA
 
[164]
2024 | Konferenz - Poster | ELSA-ID: 12397
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Process Optimization in Baked Goods Production Using Inline Sensors and Objective Product Evaluation, 2024.
ELSA
 
[163]
2024 | Preprint | ELSA-ID: 12400 | OA
Ramm, Selina, Ulrich Odefey, Björn Frahm, and Miriam Pein-Hackelbusch. “Semi-Automated vs. Manual: Comparative Study of Cell Culture Counting Methods Using Validation Parameters.” bioRxiv, 2024. https://doi.org/10.1101/2024.05.30.596619.
ELSA | DOI | Download (ext.)
 
[162]
2024 | Konferenz - Poster | ELSA-ID: 10957
Reinhardt, Lena, Veronika Gassenmeier, Sebastian Feldt, Sebastian Plate, Martin Tremmel, Björn Frahm, and Martin Stosch. Mycelium-Based Materials from Residues of the Regional Wood Industry, n.d.
ELSA
 
[161]
2024 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 12402
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken, and Marc Wichern. “Comparative Analysis of PH Prediction Routines in ADM1 and a Specialized Water Chemistry Simulator.” Chemie Ingenieur Technik 96, no. 4 (2024): 528–34. https://doi.org/10.1002/cite.202300188.
ELSA | DOI | WoS
 
[160]
2023 | Konferenz - Poster | ELSA-ID: 11378
Gassenmeier, Veronika, Giovanni Campolongo, and Björn Frahm. Real-Time Monitoring of DCO2 in Addition to DO, n.d.
ELSA
 
[159]
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann, and Björn Frahm. A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development. DECHEMA e.V., n.d.
ELSA
 
[158]
2023 | Konferenz - Poster | ELSA-ID: 11382 | OA
Gassenmeier, Veronika, Fabian Kuhfuß, Sahar Deppe, George Ifrim, Tanja Hernández Rodriguez, and Björn Frahm. View on a Mechanistic Model of Chlorella Vulgaris in Shake Flasks, n.d.
ELSA | Download (ext.)
 
[157]
2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm, and Björn Frahm. Model-Assisted Design Strategies for Bioprocesses – Advanced Statistical Methods in Industrial Upstream Cell Culture. DECHEMA e.V., 2023.
ELSA
 
[156]
2023 | Konferenzband - Beitrag | ELSA-ID: 11384 | OA
Müller, Carolin, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. Microbial Spoilage in Vegan Foods. Proceedings of the 10th International Congress of Food Technologists, Biotechnologists and Nutritionists: Smart Food for a Healthy Planet and Human Prosperity. Croatian Society of Food Technologists, Biotechnologists and Nutritionists, Zagreb, Croatia, Editors: Draženka Komes, Sanja Vidaček Filipec and Bojana Voučko, 2023.
ELSA | Download (ext.)
 
[155]
2023 | Konferenz - Poster | ELSA-ID: 11487 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm, and Miriam Pein-Hackelbusch. Comparison of Preprocessing Methods of Dielectric Spectroscopy  Data and the Effects on Linear Regression . DECHEMA e.V., n.d.
ELSA | Download (ext.)
 
[154]
2023 | Konferenz - Poster | ELSA-ID: 10201 | OA
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann, and Björn Frahm. A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development, 2023.
ELSA | Download (ext.)
 
[153]
2023 | Konferenz - Vortrag | ELSA-ID: 11109
Blome, André, Mario Luttmann, Mario Jekle, Björn Frahm, and Ulrich Müller. Untersuchung der räumlichen Verteilung von viskoelastischen Kenngrößen während der Weizenteigbereitung, 2023.
ELSA
 
[152]
2023 | Konferenz - Poster | ELSA-ID: 11110
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, 2023.
ELSA
 
[151]
2023 | Konferenz - Poster | ELSA-ID: 12483
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, 2023.
ELSA
 
[150]
2023 | Konferenz - Poster | ELSA-ID: 12485
Luttmann, Mario, André Blome, Mario Jekle, Björn Frahm, and Ulrich Müller. Teig 4.0 - Promotionsthemen, 2023.
ELSA
 
[149]
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 | OA
Ramm, Selina, Tanja Hernández Rodriguez, Björn Frahm, and Miriam Pein-Hackelbusch. Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities. Edited by Jürgen Jasperneite, Lukasz Wisniewski, Kim Fung Man, and Institute of Electrical and Electronics Engineers . 2023 IEEE 21st International Conference on Industrial Informatics (INDIN). [Piscataway, NJ]: IEEE, 2023. https://doi.org/10.1109/INDIN51400.2023.10218012.
ELSA | DOI | Download (ext.)
 
[148]
2023 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11385
Kosse, Pascal, Tanja Hernández Rodriguez, Björn Frahm, Manfred Lübken, and Marc Wichern. “Validation and Uncertainty Assessment of a Software‐Integrated Workflow for PH Calculations.” Chemie Ingenieur Technik 95, no. 12 (2023): 1960–69. https://doi.org/10.1002/cite.202300082.
ELSA | DOI | WoS
 
[147]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11377
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann, and Björn Frahm. “Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.” Processes 10, no. 5 (2022). https://doi.org/10.3390/pr10050883.
ELSA | DOI
 
[146]
2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez, Tanja, Selina Ramm, Markus Lange-Hegermann, and Björn Frahm. A Systematic, Model-Based Workflow for Risk-Based Decision Making in Upstream Development, n.d.
ELSA
 
[145]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7976
Gassenmeier, Veronika, Sahar Deppe, Tanja Hernández Rodriguez, Fabian Kuhfuß, André Moser, Volker C. Hass, Kim B. Kuchemüller, et al. “Model-Assisted DoE Applied to Microalgae Processes, Current Research in Biotechnology.” Current Research in Biotechnology 4 (2022): 102–19. https://doi.org/10.1016/j.crbiot.2022.01.005.
ELSA | DOI
 
[144]
2022 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7977
Kuhfuß, Fabian, Veronika Gassenmeier, Sahar Deppe, George Adrian Ifrim, Tanja Hernández Rodriguez, and Björn Frahm. “View on a Mechanistic Model of Chlorella Vulgaris in Incubated Shake Flasks.” Bioprocess and Biosystems Engineering 45 (2022): 15–30. https://doi.org/10.1007/s00449-021-02627-2.
ELSA | DOI
 
[143]
2022 | Datenpublikation | ELSA-ID: 10190
Gassenmeier, Veronika, and Björn Frahm. Real-Time Monitoring of DCO2 in Addition to DO. assets-labs, 2022.
ELSA | Dateien verfügbar
 
[142]
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez, Tanja, Anton Sekulic, Markus Lange-Hegermann, and Björn Frahm. “Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design.” In Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, edited by Ralf Pörtner and Johannes Möller, special issue:21–48. Processes : Open Access Journal. Basel: MDPI, 2022. https://doi.org/10.3390/pr10050883.
ELSA | DOI
 
[141]
2022 | Konferenzband - Beitrag | ELSA-ID: 10195
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Process Optimisation in the Field of Wheat Dough Processing Using Real-Time Recording of Quality-Relevant Characteristics in Raw Materials, Intermediates and Final Products. Proceedings of the 33rd VH Yeast Conference 2022: Advances in Applied Research & Industrial Production of Baker’s Yeast, “100th Anniversary of VH Berlin & Yeast(s) as an Alternative Protein Source.” Versuchsanstalt der Hefeindustrie e.V., 2022.
ELSA
 
[140]
2022 | Konferenz - Vortrag | ELSA-ID: 10196
Blome, André, Mario Luttmann, Jan Segermann, Mario Jekle, Björn Frahm, and Ulrich Müller. Process Optimisation in the Field of Wheat Dough Processing Using Real-Time Recording of Quality-Relevant Characteristics in Raw Materials, Intermediates and Final Products, 2022.
ELSA
 
[139]
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. Model Assisted Design Strategies for Bioprocesses – Advanced Statistical Methods in Industrial Upstream Cell Culture. ACHEMA 2022, 2022.
ELSA
 
[138]
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez, Tanja, Ralf Pörtner, Markus Lange-Hegermann, Florian M. Wurm, and Björn Frahm. A Systematic, Model-Based Approach for Decision Making in Upstream Development – Considerations Regarding Clone Selection and Cell Expansion, n.d.
ELSA
 
[137]
2022 | Konferenz - Poster | ELSA-ID: 10199 | OA
Müller, Carolin, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. Microbial Spoilage in Vegan Foods. PBN 2022 Congress, 2022.
ELSA | Download (ext.)
 
[136]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 11376
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm, and Björn Frahm. “Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection—A Simulation Study.” Processes 9, no. 6 (2021). https://doi.org/10.3390/pr9060964.
ELSA | DOI
 
[135]
2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez, Tanja, and Björn Frahm. Model-Based Methods in Bioprocess Technology - Bioprocess Modeling, Simulation and Prediction, 2021.
ELSA
 
[134]
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser, André, Johannes Möller, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, Björn Frahm, Ralf Pörtner, and Volker C. Hass. Model-Assisted Design of Experiments - Concept, Software and Applications, 2021.
ELSA
 
[133]
2021 | Lexikoneintrag | ELSA-ID: 7939
Wirtanen, Gun, Jarmo Alarinta, Björn Frahm, and Sylvia Fasse. “Bovine Colostrum for Human Consumption.” In MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science, 2021.
ELSA
 
[132]
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez, Tanja, Sophie Morerod, Ralf Pörtner, Florian M. Wurm, and Björn Frahm. “Considerations of the Impacts of Cell-Specific Growth and Production Rate on Clone Selection – a Simulation Study.” In Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, special issue:49–74. Processes : Open Access Journal . Basel: MDPI, 2021. https://doi.org/10.3390/pr9060964.
ELSA | DOI
 
[131]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. “Dynamic Parameter Estimation and Prediction over Consecutive Scales, Based on Moving Horizon Estimation - Applied to an Industrial Cell Culture Seed Train.” Bioprocess and Biosystems Engineering 44, no. 4 (2021): 793–808. https://doi.org/10.1007/s00449-020-02488-1 .
ELSA | DOI
 
[130]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7986
Moser, André, Kim B. Kuchemüller, Sahar Deppe, Tanja Hernández Rodriguez, Björn Frahm, Ralf Pörtner, Volker C. Hass, and Johannes Möller. “Model-Assisted DoE Software: Optimization of Growth and Biocatalysis in Saccharomyces Cerevisiae Bioprocesses.” Bioprocess and Biosystems Engineering 44, no. 4 (2021): 683–700. https://doi.org/10.1007/s00449-020-02478-3.
ELSA | DOI
 
[129]
2021 | Konferenz - Vortrag | ELSA-ID: 8078
Blome, André, Mario Luttmann, Björn Frahm, and Ulrich Müller. Messtechnikkonzepte Für Die Erfassung von Qualitätsrelevanten Parametern Und Merkmalen Bei Der Weizenteigverarbeitung. Seminar Life Science Technologies 2021-04-28, 2021.
ELSA
 
[128]
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez, Tanja, and Björn Frahm. “Digital Seed Train Twins and Statistical Methods.” In Digital Twins Tools and Concepts for Smart Biomanufacturing, edited by Christoph Herwig, Ralf Pörtner, and Johannes Möller, 176:97–131. Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer, 2021. https://doi.org/10.1007/10_2020_137.
ELSA | DOI
 
[127]
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7981
Fasse, Sylvia, Jarmo Alarinta, Björn Frahm, and Gun Wirtanen. “Bovine Colostrum for Human Consumption - Improving Microbial Quality and Maintaining Bioactive Characteristics through Processing.” Dairy 2, no. 4 (2021): 556–75. https://doi.org/10.3390/dairy2040044.
ELSA | DOI | WoS
 
[126]
2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim, and Björn Frahm. Modeling of Chlorella Vulgaris in Shake Flasks with Respect to Light Intensity and Light Duration, 2020.
ELSA
 
[125]
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes, 2020.
ELSA
 
[124]
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez, Tanja, Björn Frahm, and Christoph Posch. Integration of Prior Knowledge and Digital Tools for Uncertainty-Based Decision Support, 2020.
ELSA
 
[123]
2020 | Konferenzband - Beitrag | ELSA-ID: 7937
Hernández Rodriguez, Tanja, Sahar Deppe, Veronika Gassenmeier, Fabian Kuhfuß, Marius Tölle, George Adrian Ifrim, and Björn Frahm. Modeling of Chlorella Vulgaris Algae in Shake Flasks with Respect to Light Intensity and Light Duration. Chemie Ingenieur Technik, Tagungsband Zur 10. ProcessNet-Jahrestagung Und 34. DECHEMA-Jahrestagung Der Biotechnologen 2020. Vol. No. 9. Volume 92. Wiley, 2020. https://doi.org/10.1002/cite.202055235.
ELSA | DOI
 
[122]
2020 | Konferenzband - Beitrag | ELSA-ID: 7938
Hernández Rodriguez, Tanja, Christoph Posch, Ralf Pörtner, and Björn Frahm. Towards Integration of Prior Knowledge and Propagation of Uncertainty for Digital Twins of Biopharmaceutical Production Processes. Chemie Ingenieur Technik, Tagungsband Zur 10. ProcessNet-Jahrestagung Und 34. DECHEMA-Jahrestagung Der Biotechnologen 2020. Vol. No. 9. Volume 92. Wiley, 2020. https://doi.org/10.1002/cite.202055234.
ELSA | DOI
 
[121]
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner, and Björn Frahm. Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach. BMC Proceedings. Vol. 14. BioMed Central, 2020. https://doi.org/10.1186/s12919-020-00188-y.
ELSA | Dateien verfügbar | DOI
 
[120]
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß, F., M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, S. Deppe, George Adrian Ifrim, and Björn Frahm. Modeling of Chlorella Vulgaris in Shake Flasks with Respect to Light Intensity and Light Duration, 2020.
ELSA
 
[119]
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe, S., F. Kuhfuß, M. Tölle, Tanja Hernández Rodriguez, Veronika Gassenmeier, George Adrian Ifrim, J. Möller, et al. Model-Assisted Design of Experiments for Algae Cultivation, 2020.
ELSA
 
[118]
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, and Björn Frahm. Modeling of Microalgae in an Air-Lift Photobioreactor for Biomass Production, 2020.
ELSA
 
[117]
2020 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2392
Möller, Johannes, Tanja Hernández Rodríguez, Jan Müller, Lukas Arndt, Kim B. Kuchemüller, Björn Frahm, Regine Eibl, Dieter Eibl, and Ralf Pörtner. “Model Uncertainty-Based Evaluation of Process Strategies during Scale-up of Biopharmaceutical Processes.” Computers & Chemical Engineering 134 (2020): 1–13. https://doi.org/10.1016/j.compchemeng.2019.106693.
ELSA | DOI
 
[116]
2020 | Sammelwerk - Beitrag | ELSA-ID: 2397
Hernández Rodríguez, Tanja, and Björn Frahm. “Design, Optimization and Adaptive Control of Cell Culture Seed Trains.” In Animal Cell Biotechnology - Methods and Protocols, edited by Ralf Pörtner, 2095:251–67. Methods in Molecular Biology. Berlin, Heidelberg, New York: Springer, 2020. https://doi.org/10.1007/978-1-0716-0191-4_14.
ELSA | DOI
 
[115]
2020 | Sammelwerk - Beitrag | ELSA-ID: 2399
Deppe, S., Björn Frahm, V. C. Hass, T. Hernández Rodríguez, K. B. Kuchemüller, J. Möller, and R. Pörtner. “Estimation of Process Model Parameters.” In Animal Cell Biotechnology: Methods and Protocols, edited by Ralf Pörtner, 2095:213–34. Methods in Molecular Biology. Berlin ; Heidelberg ; New York: Springer, 2020. https://doi.org/10.1007/978-1-0716-0191-4_12.
ELSA | DOI
 
[114]
2019 | Konferenz - Vortrag | ELSA-ID: 7928
Frahm, Björn. Scale-up of Stirred Vessels, 2019.
ELSA
 
[113]
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller, J., J. Müller, Tanja Hernández Rodriguez, K. B. Kuchemüller, L. Arndt, Björn Frahm, R. Eibl, D. Eibl, and R. Pörtner. Workflow for Model-Assisted Design and Scale-up of Biopharmaceutical Production Processes, 2019.
ELSA
 
[112]
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller, J., K. B. Kuchemüller, A. Moser, V. C. Hass, Tanja Hernández Rodriguez, S. Deppe, Björn Frahm, and R. Pörtner. Model-Assisted Design of Experiments, 2019.
ELSA
 
[111]
2019 | Konferenz - Vortrag | ELSA-ID: 2958
Ifrim, George Adrian, M. Titica, S. Deppe, Björn Frahm, M. Barbu, and S. Caraman. Novel Control Strategy for Microalgae in Photobioreactor, 2019.
ELSA
 
[110]
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner, and Björn Frahm. Predicting Industrial Scale Cell Culture Seed Trains – Considerations of Input Uncertainty, New Process Data and Prognostic Intervals Using a Bayesian Approach and Sequential Bayesian Updating, 2019.
ELSA
 
[109]
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner, and Björn Frahm. Predicting Industrial Scale Cell Culture Seed Trains – Considerations of Input Uncertainty, New Process Data and Prognostic Intervals Using a Bayesian Approach and Sequential Bayesian Updating, 2019.
ELSA
 
[108]
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, S. Deppe, George Adrian Ifrim, A. Moser, V. C. Hass, Björn Frahm, and R. Pörtner. Model-Assisted Design of Experiments – Software Toolbox, 2019.
ELSA
 
[107]
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe, S., Tanja Hernández Rodriguez, Veronika Gassenmeier, M. Tölle, F. Kuhfuß, J. Möller, K. B. Kuchemüller, et al. Model-Assisted Design of Experiments for Algae Cultivation, 2019.
ELSA
 
[106]
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim, George Adrian, S. Deppe, Tanja Hernández Rodriguez, Veronika Gassenmeier, and Björn Frahm. Modeling of Microalgae in an Air-Lift Photobioreactor for Biomass Production, 2019.
ELSA
 
[105]
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez, Tanja, C. Posch, J. Schmutzhard, J. Stettner, J. Weihs, R. Pörtner, and Björn Frahm. Predicting Industrial Scale Cell Culture Seed Trains – Considerations of Input Uncertainty, New Process Data and Prognostic Intervals Using a Bayesian Approach and Sequential Bayesian Updating, 2019.
ELSA
 
[104]
2019 | Konferenz - Poster | ELSA-ID: 3006
Ifrim, George Adrian, M. Titica, S. Deppe, Björn Frahm, M. Barbu, and S. Caraman. Multivariable Control Strategy for the Photosynthetic Cultures of Microalgae, 2019.
ELSA
 
[103]
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 | OA
Hernández Rodriguez, Tanja, Christoph Posch, Julia Schmutzhard, Josef Stettner, Claus Weihs, Ralf Pörtner, and Björn Frahm. “Predicting Industrial‐scale Cell Culture Seed Trains–A Bayesian Framework for Model Fitting and Parameter Estimation, Dealing with Uncertainty in Measurements and Model Parameters, Applied to a Nonlinear Kinetic Cell Culture Model, Using an MCMC Method.” Biotechnology and Bioengineering 116, no. 11 (2019): 2944–59. https://doi.org/10.1002/bit.27125.
ELSA | DOI | Download (ext.)
 
[102]
2019 | Konferenzband - Beitrag | ELSA-ID: 2400
Ifrim, George Adrian, Mariana Titica, Sahar Deppe, Björn Frahm, Marian Barbu, and Sergiu Caraman. Multivariable Control Strategy for the Photosynthetic Cultures of Microalgae. 2019 23rd International Conference on System Theory, Control and Computing (ICSTCC). IEEE, 2019. https://doi.org/10.1109/icstcc.2019.8886109.
ELSA | DOI
 
[101]
2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez, Tanja, Björn Frahm, Christoph Posch, Julia Schmutzhard, and Josef Stettner. A Model-Assisted Approach for Design, Optimization and Control of Bioprocesses – a Software Tool for Seed Train Simulation and Optimization, 2018.
ELSA
 
[100]
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez, Tanja, Susan Krull, Volker C. Hass, Johannes Möller, Ralf Pörtner, and Björn Frahm. Model-Assisted Cell Culture Control – Unstructured, Unsegregated Models as a Key Element for Adaptive Seed Train and Fed-Batch Optimization. BMC Proceedings. Vol. 112. BioMed Central, 2018. https://doi.org/10.1186/s12919-018-0097-x.
ELSA | Dateien verfügbar | DOI
 
[99]
2018 | Konferenz - Vortrag | ELSA-ID: 2955
Pörtner, R., J. Möller, Björn Frahm, and V. C. Hass. Model-Assisted Design of Process Strategies for Cell Culture Processes, 2018.
ELSA
 
[98]
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller, J., K. B. Kuchemüller, F. Freiberger, P. Levermann, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass, and R. Pörtner. Model-Assisted Design and Optimization of Process Strategies, 2018.
ELSA
 
[97]
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez, Tanja, J. Möller, K. B. Kuchemüller, F. Freiberger, P. Levermann, V. C. Hass, Björn Frahm, and R. Pörtner. Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses, 2018.
ELSA
 
[96]
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 | OA
Möller, J., K. B. Kuchemüller, Tanja Hernández Rodriguez, Björn Frahm, V. C. Hass, and R. Pörtner. “Model-Assisted Design of Process Strategies for Cell Culture Processes.” American Pharmaceutical Review 3 (2018): 39–41.
ELSA | Download (ext.)
 
[95]
2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez, Tanja, S. Kern, O. Platas Barradas, R. Pörtner, and Björn Frahm. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren, 2017.
ELSA
 
[94]
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner, R., J. Möller, Tanja Hernández Rodriguez, Björn Frahm, and V. C. Hass. Model-Assisted Design and Optimization of Biotechnological Processes, 2017.
ELSA
 
[93]
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez, Tanja, K. S. Koopmann, J. Klaes, S. Kern, O. Platas Barradas, R. Pörtner, and Björn Frahm. Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren, 2017.
ELSA
 
[92]
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez, Tanja, K. S. Koopmann, R. Pörtner, and Björn Frahm. Influence of Parameter Accuracies in Cell Culture Seed Train Simulations, 2017.
ELSA
 
[91]
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, J. Möller, R. Pörtner, and Björn Frahm. Model-Based Cell Culture Control – Unstructured, Unsegregated Models as a Key Element for Adaptive Seed Train and Fed-Batch Optimization, 2017.
ELSA
 
[90]
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez, Tanja, S. Krull, V. C. Hass, R. Pörtner, and Björn Frahm. Model-Based Cell Culture Control – Unstructured, Unsegregated Models as a Key Element for Adaptive Seed Train and Fed-Batch Optimization, 2017.
ELSA
 
[89]
2016 | Konferenz - Poster | ELSA-ID: 2991
Beshay, U., Sebastian Feldt, B. Schwarze, P. Wefing, T. Hahne, J. Moschinski, C. Müller, et al. DMA Photobioreactor System – Cultivation at Low Shear Stress and Optional Membrane Aeration, 2016.
ELSA
 
[88]
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez, Tanja, S. Vörtler, S. Kern, O. Platas Barradas, R. Pörtner, and Björn Frahm. A Software Tool for Biopharmaceutical Seed Train Design and Optimization, 2016.
ELSA
 
[87]
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann, K. S., Tanja Hernández Rodriguez, S. Vörtler, U. Beshay, J. Möller, R. Pörtner, and Björn Frahm. Simulation of Cell Culture Seed Trains – Investigation of the Influence of Parameter Inaccuracies, 2016.
ELSA
 
[86]
2016 | Sammelwerk - Beitrag | ELSA-ID: 2395
Pörtner, R., O. Platas Barradas, Björn Frahm, and V.C. Hass. “Advanced Process and Control Strategies for Bioreactors.” In Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls, 463–93. Amsterdam: Elsevier, 2016. https://doi.org/10.1016/b978-0-444-63663-8.00016-1.
ELSA | DOI
 
[85]
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner, and Björn Frahm. Considerations for Cell Passaging in Cell Culture Seed Trains. BMC Proceedings / BioMed Central. Vol. 9. BioMed Central, 2015. https://doi.org/10.1186/1753-6561-9-s9-p43.
ELSA | DOI | Download (ext.)
 
[84]
2015 | Konferenzband - Beitrag | ELSA-ID: 2820 | OA
Kern, Simon, Oscar Platas Barradas, Martin Schaletzky, Volker Sandig, Björn Frahm, and Ralf Pörtner. Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale. BMC Proceedings / BioMed Central. Vol. 9. BioMed Central, 2015. https://doi.org/10.1186/1753-6561-9-s9-p44.
ELSA | DOI | Download (ext.)
 
[83]
2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm, Björn, R. Pörtner, S. Kern, and Tanja Hernández Rodriguez. Seed Train Design and Optimization for Animal Cell Suspension Culture, 2015.
ELSA | Dateien verfügbar
 
[82]
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm, Björn, Tanja Hernández Rodriguez, S. Kern, K. S. Koopmann, U. Beshay, O. Platas-Barradas, and R. Pörtner. Seed Train Design and Optimization for Animal Cell Suspension Culture, 2015.
ELSA
 
[81]
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. Considerations for Cell Passaging in Cell Culture Seed Trains, 2015.
ELSA
 
[80]
2015 | Konferenz - Poster | ELSA-ID: 2986
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale, 2015.
ELSA
 
[79]
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. A Software Tool for Biopharmaceutical Seed Train Design and Optimization, 2015.
ELSA
 
[78]
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. Considerations for Cell Passaging in Cell Culture Seed Trains, 2015.
ELSA
 
[77]
2015 | Konferenz - Poster | ELSA-ID: 2990
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale, 2015.
ELSA
 
[76]
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2389
Kern, Simon, Oscar Platas-Barradas, Ralf Pörtner, and Björn Frahm. “Model-Based Strategy for Cell Culture Seed Train Layout Verified at Lab Scale.” Cytotechnology 68, no. 4 (2015): 1019–32. https://doi.org/10.1007/s10616-015-9858-9.
ELSA | DOI | Download (ext.)
 
[75]
2014 | Patent | ELSA-ID: 2878
Frahm, Björn, and Uwe Meier. “Beleuchtung von Disposable Bioreaktoren,” 2014.
ELSA
 
[74]
2014 | Konferenz - Poster | ELSA-ID: 2984
Drews, F., G. Drews, C. Folz, G. Platz, Thomas Gassenmeier, M. Kramer, C. Hundeiker, B. Schwarze, and Björn Frahm. Herstellung von Paramylon mit Euglena gracilis im disposable Bag mit LED-Beleuchtung direkt auf dessen Oberfläche, 2014.
ELSA
 
[73]
2014 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2388
Hahne, T., B. Schwarze, M. Kramer, and Björn Frahm. “Disposable Algae Cultivation for High-Value Products Using All around LED-Illumination Directly on the Bags.” Journal of Algal Biomass Utilization 5, no. 2 (2014): 66–73.
ELSA
 
[72]
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 | OA
Hernández Rodriguez, Tanja, Ralf Pörtner, and Björn Frahm. Seed Train Optimization for Suspension Cell Culture. BMC Proceedings / BioMed Central . Vol. 7. BioMed Central , 2013. https://doi.org/10.1186/1753-6561-7-s6-p9.
ELSA | DOI | Download (ext.)
 
[71]
2013 | Konferenzband - Beitrag | ELSA-ID: 2818 | OA
Kern, Simon, Oscar Platas, Martin Schaletzky, Volker Sandig, Björn Frahm, and Ralf Pörtner. Model-Based Design of the First Steps of a Seed Train for Cell Culture Processes. BMC Proceedings / BioMed Central . Vol. 7. BioMed Central, 2013. https://doi.org/10.1186/1753-6561-7-s6-p11.
ELSA | DOI | Download (ext.)
 
[70]
2013 | Konferenz - Poster | ELSA-ID: 2980
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Modellgestützte Auslegung der ersten Schritte eines Seed-Trains für Zellkulturprozesse, 2013.
ELSA
 
[69]
2013 | Konferenz - Poster | ELSA-ID: 2981
Kern, S., O. Platas, M. Schaletzky, V. Sandig, Björn Frahm, and R. Pörtner. Model-Based Design of the First Steps of a Seed Train for Cell Culture Processes, 2013.
ELSA
 
[68]
2013 | Konferenz - Poster | ELSA-ID: 2982
Hahne, T., B. Schwarze, J. Moschinski, A. Kuttig, M. Kramer, and Björn Frahm. Disposable Algenkultivierung für hochpreisige Produkte mittels LED-Rundumbeleuchtung direkt auf den Bags, 2013.
ELSA
 
[67]
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, Tanja, R. Pörtner, and Björn Frahm. Seed Train Optimization for Suspension Cell Culture, 2013.
ELSA
 
[66]
2013 | Sammelwerk - Beitrag | ELSA-ID: 10214
Frahm, Björn. “Seed Train Optimization for Cell Culture.” In Animal Cell Biotechnology - Methods and Protocols, edited by Ralf Pörtner, 3rd ed., 1104:355–67. Methods in Molecular Biology. Totowa, NJ: Humana Press, 2013. https://doi.org/10.1007/978-1-62703-733-4_22.
ELSA | DOI
 
[65]
2012 | Konferenzband - Beitrag | ELSA-ID: 2816 | OA
Frahm, Björn, and H. Brod. Improving Cell Culture Bioreactor Performance for Sensitive Cell Lines by Dynamic Membrane Aeration (DMA). Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. Vol. 5. ESACT Proceedings. Dordrecht: Springer, 2012. https://doi.org/10.1007/978-94-007-0884-6_56.
ELSA | DOI | Download (ext.)
 
[64]
2012 | Patent | ELSA-ID: 2877
Brod, Helmut, and Björn Frahm. “Photobioreaktor Mit Rotatorisch Oszillierenden Lichtquellen,” 2012.
ELSA
 
[63]
2012 | Konferenz - Vortrag | ELSA-ID: 2918
Van Hecke, W., D. Haltrich, Björn Frahm, H. Brod, and R. Ludwig. Modelling and Upscaling of a Biocatalytic Cascade Oxidation in a Dynamic Membrane Aeration Reactor. Achema 2012. Vogel Business Media, 2012.
ELSA
 
[62]
2012 | Konferenz - Poster | ELSA-ID: 2973
Marzougui, R., R. Pörtner, and Björn Frahm. Optimierung des Seed trains von Suspensions-Zellkulturen, 2012.
ELSA
 
[61]
2011 | Patent | ELSA-ID: 2876
Brod, Helmut, Björn Frahm, Marc Jenne, Jörg Kauling, Franz Schmitt, and Juri Seletzky. “Flüssigkeitsbegaser,” 2011.
ELSA
 
[60]
2011 | Konferenz - Poster | ELSA-ID: 2972
Van Hecke, W., D. Haltrich, Björn Frahm, H. Brod, and R. Ludwig. Modelling and Upscaling of a Biocatalytic Cascade Oxidation in a Dynamic Membrane Aeration Reactor, 2011.
ELSA
 
[59]
2011 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2350
Van Hecke, Wouter, Dietmar Haltrich, Björn Frahm, Helmut Brod, Jo Dewulf, Herman Van Langenhove, and Roland Ludwig. “A Biocatalytic Cascade Reaction Sensitive to the Gas–Liquid Interface: Modeling and Upscaling in a Dynamic Membrane Aeration Reactor.” Journal of Molecular Catalysis B: Enzymatic 68, no. 2 (2011): 154–61. https://doi.org/10.1016/j.molcatb.2010.10.004.
ELSA | DOI | Download (ext.)
 
[58]
2010 | Konferenzband - Beitrag | ELSA-ID: 2815
Dercks, B., Björn Frahm, M. Grünewald, E. Kenig, A. Lautenschleger, A. Gorak, P. Schmidt, D. Sudhoff, S. Ressler, and R. Zecirovic. Intensified Absorption and Distillation Devices for Modular Chemical Production Processes. Proceedings 19th International Congress of Chemical and Process Engineering. Czech Society of Chemical Engineering, 2010.
ELSA
 
[57]
2010 | Patent | ELSA-ID: 2873
Brod, Helmut, Björn Frahm, and Jörg Kauling. “Verfahren Zur Reduzierung von Ablagerungen Bei Der Kultivierung von Organismen,” 2010.
ELSA
 
[56]
2010 | Patent | ELSA-ID: 2874
Brod, Helmut, Björn Frahm, Marc Jenne, and Jörg Kauling. “Bioreaktor,” 2010.
ELSA
 
[55]
2010 | Patent | ELSA-ID: 2875
Frahm, Björn, Jörg Kauling, Andre Pütz, and Markus Schindler. “Begasungssystem,” 2010.
ELSA
 
[54]
2010 | Konferenz - Vortrag | ELSA-ID: 2892
Frahm, Björn, and Helmut Brod. Cultivation of Sensitive Cell Lines - Improving Bioreactor Performance by Dynamic Membrane Aeration, 2010.
ELSA
 
[53]
2010 | Konferenz - Vortrag | ELSA-ID: 2913
Dercks, B., Björn Frahm, M. Grünewald, E. Kenig, A. Lautenschleger, A. Gorak, P. Schmidt, D. Sudhoff, S. Ressler, and R. Zecirovic. Intensified Absorption and Distillation Devices for Modular Chemical Production Processes, 2010.
ELSA
 
[52]
2009 | Patent | ELSA-ID: 2872
Braun, Arndt, Helmut Brod, Björn Frahm, Marc Jenne, Jörg Kauling, and Stephan Kirchner. “Verfahren Und Vorrichtung Zur Rückhaltung Und Rückführung von Zellen,” 2009.
ELSA
 
[51]
2009 | Konferenz - Vortrag | ELSA-ID: 2912
Frahm, Björn, H. Brod, and U. Langer. Improving Cell Culture Bioreactor Performance by Dynamic Membrane Aeration (DMA), 2009.
ELSA
 
[50]
2009 | Konferenz - Poster | ELSA-ID: 2970
Frahm, Björn, H. Brod, and U. Langer. Improving Cell Culture Bioreactor Performance by Dynamic Membrane Aeration (DMA), 2009.
ELSA
 
[49]
2009 | Konferenz - Poster | ELSA-ID: 2971
Van Hecke, W., H. Van Langenhovve, Björn Frahm, H. Brod, J. Dewulf, D. Haltrich, and R. Ludwig. Upscaling the Biocatalytic Conversion of Lactose to Lactobionic Acid with the Dynamic Membrane Aeration Reactor, 2009.
ELSA
 
[48]
2009 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2349 | OA
Frahm, Björn, Helmut Brod, and Uwe Langer. “Improving Bioreactor Cultivation Conditions for Sensitive Cell Lines by Dynamic Membrane Aeration.” Cytotechnology 59, no. 1 (2009): 17–30. https://doi.org/10.1007/s10616-009-9189-9.
ELSA | DOI | Download (ext.)
 
[47]
2008 | Konferenz - Vortrag | ELSA-ID: 2911
Brod, H., J. Kauling, Björn Frahm, M. Jenne, U. Langer, and B. Bödeker. Pushing the Limits in High-Density Mammalian Cell Fermentation, 2008.
ELSA
 
[46]
2008 | Konferenz - Poster | ELSA-ID: 2968
Frahm, Björn, H. Brod, M. Burnett, U. Langer, and B. Bödeker. High Cell Density Bioreactor Cultivation by Dynamic Membrane Aeration (DMA), 2008.
ELSA
 
[45]
2008 | Konferenz - Poster | ELSA-ID: 2969
Frahm, Björn, and Helmut Brod. High Cell Density Bioreactor Cultivation by Dynamic Membrane Aeration (DMA), 2008.
ELSA
 
[44]
2007 | Konferenzband - Beitrag | ELSA-ID: 2814
Pörtner, Ralf, Björn Frahm, Paul Lane, Axel Munack, Kathrin Kühn, and Volker C. Hass. Optimisation of Time-Space-Yield for Hybridoma Fed-Batch Cultures with an Adaptive Olfo-Controller. Cell Technology for Cell Products. Vol. 3. ESACT Proceedings. Dordrecht: Springer, 2007. https://doi.org/10.1007/978-1-4020-5476-1_84.
ELSA | DOI
 
[43]
2007 | Patent | ELSA-ID: 2870 | OA
Brod, Helmut, Björn Frahm, Jörg Kauling, and Reinhold Rose. “Procedure for Gassing of Liquid for Cell Cultures, Comprises Exchanging of Gas over Immersed Membrane Surfaces and Controlling the Gassing Rate Change of the Gas Concentration and/or Pressure of the Gas or Gas Mixture or Gas Component,” 2007.
ELSA | Download (ext.)
 
[42]
2007 | Patent | ELSA-ID: 2871
Brod, Helmut, Björn Frahm, Jörg Kauling, Martin Poggel, Reinhold Rose, and Sebastian Schmidt. “Verfahren Und Vorrichtung Zur Be- Und Entgasung von Flüssigkeiten, Insbesondere in Der Biotechnologie Und Speziell von Zellkulturen,” 2007.
ELSA
 
[41]
2007 | Konferenz - Vortrag | ELSA-ID: 2909
Brod, Helmut, Björn Frahm, and Jörg Kauling. Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen, 2007.
ELSA
 
[40]
2007 | Konferenz - Vortrag | ELSA-ID: 2910
Brod, Helmut, Björn Frahm, and Jörg Kauling. Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen, 2007.
ELSA
 
[39]
2007 | Konferenz - Poster | ELSA-ID: 2967
Frahm, Björn, S. Kirchner, R. Rose, M. Jenne, J. Kauling, H. Brod, K. Jöris, M. Wischniewski, U. Langer, and B. Bödeker. High Cell Density Bioreactor Cultivation by Dynamic Membrane Aeration (DMA), 2007.
ELSA
 
[38]
2007 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2348
Frahm, Björn, S. Kirchner, J. Kauling, H. Brod, U. Langer, and B. Bödeker. “Dynamische Membranbegasung im Bioreaktor zur Intensivierung der Sauerstoffversorgung empfindlicher Zelllinien.” Chemie Ingenieur Technik 79, no. 7 (2007): 1052–58. https://doi.org/10.1002/cite.200700070.
ELSA | DOI | Download (ext.)
 
[37]
2005 | Konferenzband - Beitrag | ELSA-ID: 2813
Frahm, Björn, and R. Pörtner. Flexible Fed-Batch Process Control of Animal Cells. Animal Cell Technology Meets Genomics. Vol. 2. ESACT Proceedings. Dordrecht: Springer, 2005. https://doi.org/10.1007/1-4020-3103-3_142.
ELSA | DOI
 
[36]
2005 | Konferenz - Vortrag | ELSA-ID: 2907
Pörtner, Ralf, Björn Frahm, P. Lane, and A. Munack. Optimisation of Time-Space-Yield for Hybridoma Fed-Batch Cultures with an Adaptive OLFO-Controller, 2005.
ELSA
 
[35]
2005 | Konferenz - Vortrag | ELSA-ID: 2908
Pörtner, R., Björn Frahm, V. C. Hass, P. Lane, and A. Munack. Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode, 2005.
ELSA
 
[34]
2005 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2347 | OA
Frahm, Björn, Paul Lane, Axel Munack, and Ralf Pörtner. “Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode.” Chemie Ingenieur Technik 77, no. 4 (2005): 429–35. https://doi.org/10.1002/cite.200407094.
ELSA | DOI | Download (ext.)
 
[33]
2004 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2345 | OA
Pörtner, Ralf, Jan-Oliver Schwabe, and Björn Frahm. “Evaluation of Selected Control Strategies for Fed-Batch Cultures of a Hybridoma Cell Line.” Biotechnology and Applied Biochemistry 40 (2004). https://doi.org/10.1042/ba20030168.
ELSA | DOI | Download (ext.)
 
[32]
2003 | Konferenz - Vortrag | ELSA-ID: 7934
Frahm, Björn, and Ralf Pörtner. Fed-Batch-Cultivation of Animal Cells: Model-Based, Adaptive Control in Comparison to Alternative Control Strategies, 2003.
ELSA
 
[31]
2003 | Konferenzband - Beitrag | ELSA-ID: 2435
Frahm, Björn, B. Müller-Landré, G. Wiggers de Almeida, M. Singer, M. Rausch, P. Lane, A. Munack, V. C. Hass, and R. Pörtner. Fed-Batch Cultivation of Animal Cells - a Challenge for Adaptive, Model-Based Control. Edited by Dieter Beckmann and Heiligenstädter Kolloquium (11 : 2002 : Heiligenstadt, Eichsfeld). Technische Systeme Für Biotechnologie Und Umwelt. Heiligenstadt: Inst. für Bioprozess- und Analysenmesstechnik , 2003.
ELSA
 
[30]
2003 | Konferenzband - Beitrag | ELSA-ID: 2436
Kühn, K., Björn Frahm, R. Pörtner, P. Lane, A. Munack, and V. C. Hass. Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells. Edited by European Federation of Chemical Engineering. ECCE - 4th European Congress of Chemical Engineering. Vol. 10. Granada: ECCE4, 2003.
ELSA
 
[29]
2003 | Konferenz - Vortrag | ELSA-ID: 2902
Frahm, Björn, and Ralf Pörtner. Fed-Batch-Kultivierungen tierischer Zellen – eine Herausforderung an eine modellgestützte, adaptive Steuerung, 2003.
ELSA
 
[28]
2003 | Konferenz - Vortrag | ELSA-ID: 2903
Hass, V. C. , K. Kühn, Björn Frahm, R. Pörtner, P. Lane, and A. Munack. Ein strukturiertes Kompartiment-Modell zur Beschreibung der Kultivierung von Hybridomazellen als Teil einer adaptiven, modellgestützten Prozessführung, 2003.
ELSA
 
[27]
2003 | Konferenz - Vortrag | ELSA-ID: 2905
Frahm, Björn, P. Lane, A. Munack, V. C. Hass, and Ralf Pörtner. Fed-Batch-Cultivation of Animal Cells: Model-Based, Adaptive Control in Comparison to Alternative Control Strategies, 2003.
ELSA | Dateien verfügbar
 
[26]
2003 | Konferenz - Vortrag | ELSA-ID: 2906
Pörtner, Ralf, Björn Frahm, P. Lane, V. C. Hass, A. Munack, and H. Märkl. Fed-Batch-Kultivierung tierischer Zellen – eine Herausforderung für eine adaptive, modellgestützte Steuerung, 2003.
ELSA
 
[25]
2003 | Konferenz - Poster | ELSA-ID: 2964
Frahm, Björn, and Ralf Pörtner. CO2-off-Gas Measurement for Animal Cell Culture Processes, 2003.
ELSA
 
[24]
2003 | Konferenz - Poster | ELSA-ID: 2965
Frahm, Björn, and Ralf Pörtner. Flexible Fed-Batch Process Control of Animal Cells, 2003.
ELSA
 
[23]
2003 | Konferenz - Poster | ELSA-ID: 2966
Kühn, K., Björn Frahm, Ralf Pörtner, P. Lane, A. Munack, and V. C. Hass. Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells, 2003.
ELSA
 
[22]
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2343 | OA
Frahm, Björn, V. C. Hass, P. Lane, A. Munack, H. Märkl, and R. Pörtner. “Fed-Batch-Kultivierung tierischer Zellen - Eine Herausforderung zur adaptiven, modellbasierten Steuerung.” Chemie Ingenieur Technik 75, no. 4 (2003): 457–60. https://doi.org/10.1002/cite.200390093.
ELSA | DOI | Download (ext.)
 
[21]
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2344 | OA
Frahm, Björn, P. Lane, H. Märkl, and R. Pörtner. “Improvement of a Mammalian Cell Culture Process by Adaptive, Model-Based Dialysis Fed-Batch Cultivation and Suppression of Apoptosis.” Bioprocess and Biosystems Engineering 26, no. 1 (2003): 1–10. https://doi.org/10.1007/s00449-003-0335-z.
ELSA | DOI | Download (ext.)
 
[20]
2003 | Dissertation | ELSA-ID: 2393
Frahm, Björn. Adaptive, modellgestützte Prozessführung von Suspensionskulturen tierischer Zellen. Norderstedt: Books on Demand GmbH, 2003.
ELSA
 
[19]
2002 | Konferenzband - Beitrag | ELSA-ID: 2431
Frahm, Björn, and Ralf Pörtner. Messung Und Simulation Des Kohlendioxidausstoßes von Zellkulturprozessen. Edited by Heiner Kaden and Forum Innovative Biosystemtechnik - Sensorik, Aktorik und Auswertung Biotechnologischer Prozesse (2001 : Waldheim). Biosystemtechnik: Innovative Biosystemtechnik - Sensorik, Aktorik Und Auswertung Biotechnologischer Prozesse. Meinsberg : Kurt-Schwabe-Inst. , 2002.
ELSA
 
[18]
2002 | Konferenz - Vortrag | ELSA-ID: 2897
Frahm, Björn, and Ralf Pörtner. Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen, 2002.
ELSA
 
[17]
2002 | Konferenz - Vortrag | ELSA-ID: 2898
Frahm, Björn, and Ralf Pörtner. Adaptive, Model-Based Control by the OLFO-Controller for the Fed-Batch Cultivation of Animal Cells, 2002.
ELSA
 
[16]
2002 | Konferenz - Vortrag | ELSA-ID: 2899
Frahm, Björn, and Ralf Pörtner. Adaptive, Model-Based Control by the OLFO-Controller for the Fed-Batch Cultivation of Animal Cells, 2002.
ELSA
 
[15]
2002 | Konferenz - Vortrag | ELSA-ID: 2900
Frahm, Björn, B. Müller-Landré, G. Wiggers de Almeida, M. Singer, M. Rausch, P. Lane, A. Munack, V. C. Hass, and R. Pörtner. Fed-Batch Cultivation of Animal Cells - a Challenge for Adaptive, Model-Based Control, 2002.
ELSA
 
[14]
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2340 | OA
Frahm, Björn, H.-C. Blank, P. Cornand, W. Oelßner, U. Guth, P. Lane, A. Munack, K. Johannsen, and R. Pörtner. “Determination of Dissolved CO2 Concentration and CO2 Production Rate of Mammalian Cell Suspension Culture Based on Off-Gas Measurement.” Journal of Biotechnology 99, no. 2 (2002): 133–48. https://doi.org/10.1016/S0168-1656(02)00180-3.
ELSA | DOI | Download (ext.)
 
[13]
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2341 | OA
Frahm, Björn, P. Lane, H. Atzert, A. Munack, M. Hoffmann, V. C. Hass, and R. Pörtner. “Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Effective Fed-Batch Cultivation of Hybridoma Cells.” Biotechnology Progress 18, no. 5 (2002): 1095–1103. https://doi.org/10.1021/bp020035y.
ELSA | DOI | Download (ext.)
 
[12]
2002 | Zeitschriftenaufsatz | ELSA-ID: 2342
Frahm, Björn, and R. Pörtner. “Reaktor-Abgasmessungen bei Zellkulturen.” BIOforum 4 (2002): 179–80.
ELSA
 
[11]
2001 | Konferenz - Vortrag | ELSA-ID: 7933
Frahm, Björn, and Ralf Pörtner. Messung Und Simulation Des Kohlendioxidausstoßes von Zellkulturprozessen, 2001.
ELSA
 
[10]
2001 | Konferenzband - Beitrag | ELSA-ID: 2427
Frahm, Björn, H. Atzert, P. Lane, M. Hoffmann, V. C. Hass, A. Munack, and Ralf Pörtner. Development of an Automated, Adaptive Model-Based Control for the Effective Cultivation of Hybridoma Cells. Animal Cell Technology: From Target to Market. Vol. 1. ESACT Proceedings. Dordrecht: Springer, 2001. https://doi.org/10.1007/978-94-010-0369-8_107.
ELSA | DOI
 
[9]
2001 | Konferenz - Poster | ELSA-ID: 2429
Hass, V. C., P. Lane, M. Hoffmann, Björn Frahm, J.-O. Schwabe, R. Pörtner, and A. Munack. Model-Based Control of Hybridoma Cell Cultures, 2001.
ELSA
 
[8]
2001 | Konferenz - Vortrag | ELSA-ID: 2894
Hoffmann, M., V. C. Hass, Björn Frahm, J.-O. Schwabe, R. Pörtner, P. Lane, and A. Munack. Untersuchung verschiedener mathematischer Modelle in Hinblick auf ihre Eignung für die adaptive Prozessführung von Hybridoma Zellkulturen, 2001.
ELSA
 
[7]
2001 | Konferenz - Vortrag | ELSA-ID: 2895
Frahm, Björn, and R. Pörtner. Arbeitsschwerpunkte TUHH, Bioprozess- und Bioverfahrenstechnik, Arbeitsgruppe Zellkulturtechnik, 2001.
ELSA
 
[6]
2001 | Konferenz - Poster | ELSA-ID: 2960
Frahm, Björn, H. Atzert, J.-O. Schwabe, P. Lane, A. Munack, M. Hoffmann, V. C. Hass, and R. Pörtner. Adaptive Modellgestützte Steuerung von Zellkulturprozessen, 2001.
ELSA
 
[5]
2001 | Konferenz - Poster | ELSA-ID: 2961
Lane, P., Björn Frahm, H. Atzert, J.-O. Schwabe, M. Hoffmann, V. C. Hass, and R. Pörtner. Design of Feeding Strategies for Fed-Batch Cultures of Animal Cells by the Method of Inequalities, 2001.
ELSA
 
[4]
2001 | Konferenz - Poster | ELSA-ID: 2962
Frahm, Björn, H. Atzert, P. Lane, M. Hoffmann, V. C. Hass, A. Munack, and R. Pörtner. Development of an Automated, Model-Based, Adaptive Control for the Effective Cultivation of Hybridoma Cells, 2001.
ELSA
 
[3]
2001 | Konferenzband - Beitrag | ELSA-ID: 2963 | OA
Hass, V.C., P. Lane, M. Hoffmann, Björn Frahm, J.-O. Schwabe, R. Pörtner, and A. Munack. Model-Based Control of Hybridoma Cell Cultures. Edited by Published for the International Federation of Automatic Control by Pergamon . Computer Applications in Biotechnology, 2001: Modelling, Monitoring and Control of Biotechnological Processes. Vol. 34.   IFAC Proceedings Volumes / IFAC, International Federation of Automatic Control. Oxford: ScienceDirect, 2001. https://doi.org/10.1016/S1474-6670(17)34240-4.
ELSA | DOI | Download (ext.)
 
[2]
2000 | Konferenz - Vortrag | ELSA-ID: 2893
Anderelei, T., Björn Frahm, and J. Büchs. Online-Bestimmung der Sauerstofftransferrate (OTR) und der Kohlendioxidtransferrate (CTR) in geschüttelten Bioreaktoren, 2000.
ELSA
 
[1]
2000 | Konferenz - Poster | ELSA-ID: 2959
Hoffmann, M., Björn Frahm, J.-O. Schwabe, P. Lane, R. Pörtner, V. C. Hass, and A. Munack. Modellgestützte Prozessführung Für Hybridoma-Kulturen Mit Hilfe Des Open-Loop-Feedback-Optimal (OLFO)- Algorithmus, 2000.
ELSA
 
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