168 Publikationen
2024 | Konferenz - Vortrag | ELSA-ID: 12021
Segermann, Jan u. a.: Die Rolle von ML-Modellen in der Lebensmitteltechnologie: Eine Fallstudie zur Sauerteigfermentation mit NIR-Spektroskopie, o. O. 2024.
ELSA
2024 | Konferenz - Vortrag | ELSA-ID: 12022
Luttmann, Mario u. a.: Erkenntnisse zur Nutzung von Photogrammmetrie für die Untersuchung des Bräunungsverhaltens von Weizenbrötchen, o. O. 2024.
ELSA
2024 | Konferenz - Poster | ELSA-ID: 12395
Müller, Carolin u. a.: Investigation of microbial spoilage in vegan foods, o. O. 2024.
ELSA
2024 | Konferenz - Poster | ELSA-ID: 12396
Gassenmeier, Veronika/Campolongo, Giovanni/Frahm, Björn: Dissolved Carbon Dioxide in Addition to Dissolved Oxygen for In-situ Monitoring of Hybridoma Cell Culture, o. O. 2024.
ELSA
2024 | Konferenz - Poster | ELSA-ID: 12397
Blome, André u. a.: Process optimization in baked goods production using inline sensors and objective product evaluation, o. O. 2024.
ELSA
2024 | Preprint | ELSA-ID: 12400 |

Ramm, Selina u. a.: Semi-automated vs. manual: Comparative study of cell culture counting methods using validation parameters, o. O. 2024.
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2024 | Konferenz - Poster | ELSA-ID: 10957
Reinhardt, Lena u. a.: Mycelium-based materials from residues of the regional wood industry, o. O. u. J. .
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11378
Gassenmeier, Veronika/Campolongo, Giovanni/Frahm, Björn: Real-time Monitoring of DCO2 in addition to DO, o. O. u. J. .
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez, Tanja u. a.: A systematic, model-based workflow for risk-based decision making in upstream development, o. O. u. J. .
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11382 |

Gassenmeier, Veronika u. a.: View on a mechanistic model of Chlorella vulgaris in shake flasks, o. O. u. J. .
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2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez, Tanja u. a.: Model-assisted design strategies for bioprocesses – Advanced statistical methods in industrial upstream cell culture, o. O. 2023.
ELSA
2023 | Konferenzband - Beitrag | ELSA-ID: 11384 |

Müller, Carolin u. a.: Microbial spoilage in vegan foods, o. O. 2023.
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2023 | Konferenz - Poster | ELSA-ID: 11487 |

Ramm, Selina u. a.: Comparison of Preprocessing Methods of Dielectric Spectroscopy Data and the Effects on Linear Regression , o. O. u. J. .
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2023 | Konferenz - Poster | ELSA-ID: 10201 |

Hernández Rodriguez, Tanja u. a.: A systematic, model-based workflow for risk-based decision making in upstream development, o. O. 2023.
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2023 | Konferenz - Vortrag | ELSA-ID: 11109
Blome, André u. a.: Untersuchung der räumlichen Verteilung von viskoelastischen Kenngrößen während der Weizenteigbereitung, o. O. 2023.
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11110
Blome, André u. a.: Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, o. O. 2023.
ELSA
2023 | Konferenz - Poster | ELSA-ID: 12483
Blome, André u. a.: Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, o. O. 2023.
ELSA
2023 | Konferenz - Poster | ELSA-ID: 12485
Luttmann, Mario u. a.: Teig 4.0 - Promotionsthemen, o. O. 2023.
ELSA
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 |

Ramm, Selina u. a.: Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities, hg. von Jasperneite, Jürgen u. a., [Piscataway, NJ] 2023.
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2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez, Tanja u. a.: A systematic, model-based workflow for risk-based decision making in upstream development, o. O. u. J. .
ELSA
2022 | Datenpublikation | ELSA-ID: 10190
Gassenmeier, Veronika/Frahm, Björn: Real-time Monitoring of DCO2 in addition to DO, o. O. 2022.
ELSA
| Dateien verfügbar
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez, Tanja u. a.: Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design, in: Pörtner, Ralf/Möller, Johannes (Hgg.): Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, Band special issue, Basel 2022 (Processes : open access journal), S. 21–48.
ELSA
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2022 | Konferenzband - Beitrag | ELSA-ID: 10195
Blome, André u. a.: Process optimisation in the field of wheat dough processing using real-time recording of quality-relevant characteristics in raw materials, intermediates and final products, o. O. 2022.
ELSA
2022 | Konferenz - Vortrag | ELSA-ID: 10196
Blome, André u. a.: Process optimisation in the field of wheat dough processing using real-time recording of quality-relevant characteristics in raw materials, intermediates and final products, o. O. 2022.
ELSA
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez, Tanja u. a.: Model assisted Design Strategies for Bioprocesses – Advanced statistical methods in industrial upstream cell culture, o. O. 2022.
ELSA
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez, Tanja u. a.: A systematic, model-based approach for decision making in upstream development – Considerations regarding clone selection and cell expansion, o. O. u. J. .
ELSA
2022 | Konferenz - Poster | ELSA-ID: 10199 |

Müller, Carolin u. a.: Microbial spoilage in vegan foods, o. O. 2022.
ELSA
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2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez, Tanja/Frahm, Björn: Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction, o. O. 2021.
ELSA
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser, André et. al. (2021): Model-assisted Design of Experiments - Concept, Software and Applications.
ELSA
2021 | Lexikoneintrag | ELSA-ID: 7939
Wirtanen, Gun et. al. (2021): Bovine Colostrum for Human Consumption, in: MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science.
ELSA
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez, Tanja u. a.: Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study, in: o. Hg.: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, Band special issue, Basel 2021 (Processes : open access journal ), S. 49–74.
ELSA
| DOI
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez, Tanja u. a.: Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train, in: Bioprocess and Biosystems Engineering 44 (2021), H. 4, S. 793–808.
ELSA
| DOI
2021 | Konferenz - Vortrag | ELSA-ID: 8078
Blome, André u. a.: Messtechnikkonzepte für die Erfassung von qualitätsrelevanten Parametern und Merkmalen bei der Weizenteigverarbeitung, o. O. 2021.
ELSA
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez, Tanja/Frahm, Björn: Digital Seed Train Twins and Statistical Methods, in: Herwig, Christoph/Pörtner, Ralf/Möller, Johannes (Hgg.): Digital Twins Tools and Concepts for Smart Biomanufacturing, Bd. 176, Berlin, Heidelberg 2021 (Advances in Biochemical Engineering/Biotechnology), S. 97–131.
ELSA
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2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez, Tanja et. al. (2020): Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez, Tanja et. al. (2020): Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes.
ELSA
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez, Tanja et. al. (2020): Integration of prior knowledge and digital tools for uncertainty-based decision support.
ELSA
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez, Tanja et. al. (2020): Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach (= 14).
ELSA
| Dateien verfügbar
| DOI
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß, F. et. al. (2020): Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe, S. et. al. (2020): Model-assisted Design of Experiments for algae cultivation.
ELSA
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim, George Adrian et. al. (2020): Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
2020 | Sammelwerk - Beitrag | ELSA-ID: 2397
Hernández Rodríguez, Tanja/Frahm, Björn (2020): Design, Optimization and Adaptive Control of Cell Culture Seed Trains, in: Ralf Pörtner (Hg.): Animal Cell Biotechnology - Methods and Protocols (=Methods in Molecular Biology 2095), Berlin, Heidelberg, New York, S. 251–267.
ELSA
| DOI
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller, J. et. al. (2019): Workflow for model-assisted design and scale-up of biopharmaceutical production processes.
ELSA
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller, J. et. al. (2019): Model-Assisted Design of Experiments.
ELSA
2019 | Konferenz - Vortrag | ELSA-ID: 2958
Ifrim, George Adrian et. al. (2019): Novel control strategy for microalgae in photobioreactor.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller, J. et. al. (2019): Model-Assisted Design of Experiments – Software Toolbox.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe, S. et. al. (2019): Model-assisted Design of Experiments for algae cultivation.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim, George Adrian et. al. (2019): Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3006
Ifrim, George Adrian et. al. (2019): Multivariable control strategy for the photosynthetic cultures of microalgae.
ELSA
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 |

Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial‐scale cell culture seed trains–A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method, in: Biotechnology and Bioengineering 116 (11), S. 2944–2959.
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2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez, Tanja et. al. (2018): A model-assisted approach for design, optimization and control of bioprocesses – a software tool for seed train simulation and optimization.
ELSA
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez, Tanja et. al. (2018): Model-assisted cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization (= 112).
ELSA
| Dateien verfügbar
| DOI
2018 | Konferenz - Vortrag | ELSA-ID: 2955
Pörtner, R. et. al. (2018): Model-Assisted Design of Process Strategies for Cell Culture Processes.
ELSA
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller, J. et. al. (2018): Model-Assisted Design and Optimization of Process Strategies.
ELSA
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez, Tanja et. al. (2018): Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses.
ELSA
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 |

Möller, J. et. al. (2018): Model-Assisted Design of Process Strategies for Cell Culture Processes, in: American Pharmaceutical Review 3, S. 39–41.
ELSA
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2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez, Tanja et. al. (2017): Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner, R. et. al. (2017): Model-assisted design and optimization of biotechnological processes.
ELSA
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez, Tanja et. al. (2017): Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez, Tanja et. al. (2017): Influence of parameter accuracies in cell culture seed train simulations.
ELSA
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez, Tanja et. al. (2017): Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez, Tanja et. al. (2017): Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
2016 | Konferenz - Poster | ELSA-ID: 2991
Beshay, U. et. al. (2016): DMA Photobioreactor System – Cultivation at low shear stress and optional membrane aeration.
ELSA
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez, Tanja et. al. (2016): A software tool for biopharmaceutical seed train design and optimization.
ELSA
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann, K. S. et. al. (2016): Simulation of cell culture seed trains – investigation of the influence of parameter inaccuracies.
ELSA
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 |

Hernández Rodriguez, Tanja et. al. (2015): Considerations for cell passaging in cell culture seed trains (= 9).
ELSA
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2015 | Konferenzband - Beitrag | ELSA-ID: 2820 |

Kern, Simon et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale (= 9).
ELSA
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2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm, Björn et. al. (2015): Seed train design and optimization for animal cell suspension culture.
ELSA
| Dateien verfügbar
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm, Björn et. al. (2015): Seed train design and optimization for animal cell suspension culture.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez, Tanja et. al. (2015): Considerations for cell passaging in cell culture seed trains.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2986
Kern, S. et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez, Tanja et. al. (2015): A software tool for biopharmaceutical seed train design and optimization.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez, Tanja et. al. (2015): Considerations for cell passaging in cell culture seed trains.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2990
Kern, S. et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale.
ELSA
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2389
Kern, Simon et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale, in: Cytotechnology 68 (4), S. 1019–1032.
ELSA
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2014 | Patent | ELSA-ID: 2878
Frahm, Björn/Meier, Uwe (2014): Beleuchtung von disposable Bioreaktoren.
ELSA
2014 | Konferenz - Poster | ELSA-ID: 2984
Drews, F. et. al. (2014): Herstellung von Paramylon mit Euglena gracilis im disposable Bag mit LED-Beleuchtung direkt auf dessen Oberfläche.
ELSA
2014 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2388
Hahne, T. et. al. (2014): Disposable algae cultivation for high-value products using all around LED-illumination directly on the bags, in: Journal of Algal Biomass Utilization 5 (2), S. 66–73.
ELSA
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 |

Hernández Rodriguez, Tanja et. al. (2013): Seed train optimization for suspension cell culture (= 7).
ELSA
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2013 | Konferenzband - Beitrag | ELSA-ID: 2818 |

Kern, Simon et. al. (2013): Model-based design of the first steps of a seed train for cell culture processes (= 7).
ELSA
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2013 | Konferenz - Poster | ELSA-ID: 2980
Kern, S. et. al. (2013): Modellgestützte Auslegung der ersten Schritte eines Seed-Trains für Zellkulturprozesse.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2981
Kern, S. et. al. (2013): Model-based design of the first steps of a seed train for cell culture processes.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2982
Hahne, T. et. al. (2013): Disposable Algenkultivierung für hochpreisige Produkte mittels LED-Rundumbeleuchtung direkt auf den Bags.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, Tanja et. al. (2013): Seed train optimization for suspension cell culture.
ELSA
2012 | Konferenzband - Beitrag | ELSA-ID: 2816 |

Frahm, Björn/Brod, H. (2012): Improving Cell Culture Bioreactor Performance for Sensitive Cell Lines by Dynamic Membrane Aeration (DMA) (=ESACT Proceedings 5), Dordrecht.
ELSA
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2012 | Patent | ELSA-ID: 2877
Brod, Helmut/Frahm, Björn (2012): Photobioreaktor mit rotatorisch oszillierenden Lichtquellen.
ELSA
2012 | Konferenz - Vortrag | ELSA-ID: 2918
Van Hecke, W. et. al. (2012): Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor.
ELSA
2012 | Konferenz - Poster | ELSA-ID: 2973
Marzougui, R. et. al. (2012): Optimierung des Seed trains von Suspensions-Zellkulturen.
ELSA
2011 | Konferenz - Poster | ELSA-ID: 2972
Van Hecke, W. et. al. (2011): Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor.
ELSA
2011 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2350
Van Hecke, Wouter et. al. (2011): A biocatalytic cascade reaction sensitive to the gas–liquid interface: Modeling and upscaling in a dynamic membrane aeration reactor, in: Journal of Molecular Catalysis B: Enzymatic 68 (2), S. 154–161.
ELSA
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2010 | Konferenzband - Beitrag | ELSA-ID: 2815
Dercks, B. et. al. (2010): Intensified absorption and distillation devices for modular chemical production processes.
ELSA
2010 | Patent | ELSA-ID: 2873
Brod, Helmut et. al. (2010): Verfahren zur Reduzierung von Ablagerungen bei der Kultivierung von Organismen.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2892
Frahm, Björn/Brod, Helmut (2010): Cultivation of sensitive cell lines - Improving bioreactor performance by Dynamic Membrane Aeration.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2913
Dercks, B. et. al. (2010): Intensified absorption and distillation devices for modular chemical production processes.
ELSA
2009 | Patent | ELSA-ID: 2872
Braun, Arndt et. al. (2009): Verfahren und Vorrichtung zur Rückhaltung und Rückführung von Zellen.
ELSA
2009 | Konferenz - Vortrag | ELSA-ID: 2912
Frahm, Björn et. al. (2009): Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA).
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2970
Frahm, Björn et. al. (2009): Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA).
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2971
Van Hecke, W. et. al. (2009): Upscaling the biocatalytic conversion of lactose to lactobionic acid with the dynamic membrane aeration reactor.
ELSA
2009 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2349 |

Frahm, Björn et. al. (2009): Improving bioreactor cultivation conditions for sensitive cell lines by dynamic membrane aeration, in: Cytotechnology 59 (1), S. 17–30.
ELSA
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2008 | Konferenz - Vortrag | ELSA-ID: 2911
Brod, H. et. al. (2008): Pushing the Limits in High-Density Mammalian Cell Fermentation.
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2968
Frahm, Björn et. al. (2008): High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA).
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2969
Frahm, Björn/Brod, Helmut (2008): High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA).
ELSA
2007 | Patent | ELSA-ID: 2870 |

Brod, Helmut et. al. (2007): Procedure for gassing of liquid for cell cultures, comprises exchanging of gas over immersed membrane surfaces and controlling the gassing rate change of the gas concentration and/or pressure of the gas or gas mixture or gas component.
ELSA
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2007 | Patent | ELSA-ID: 2871
Brod, Helmut et. al. (2007): Verfahren und Vorrichtung zur Be- und Entgasung von Flüssigkeiten, insbesondere in der Biotechnologie und speziell von Zellkulturen.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2909
Brod, Helmut et. al. (2007): Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2910
Brod, Helmut et. al. (2007): Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen.
ELSA
2007 | Konferenz - Poster | ELSA-ID: 2967
Frahm, Björn et. al. (2007): High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA).
ELSA
2007 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2348
Frahm, Björn et. al. (2007): Dynamische Membranbegasung im Bioreaktor zur Intensivierung der Sauerstoffversorgung empfindlicher Zelllinien, in: Chemie Ingenieur Technik 79 (7), S. 1052–1058.
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2005 | Konferenz - Vortrag | ELSA-ID: 2907
Pörtner, Ralf et. al. (2005): Optimisation of time-space-yield for hybridoma fed-batch cultures with an adaptive OLFO-controller.
ELSA
2005 | Konferenz - Vortrag | ELSA-ID: 2908
Pörtner, R. et. al. (2005): Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode.
ELSA
2005 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2347 |

Frahm, Björn et. al. (2005): Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode, in: Chemie Ingenieur Technik 77 (4), S. 429–435.
ELSA
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2004 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2345 |

Pörtner, Ralf et. al. (2004): Evaluation of selected control strategies for fed-batch cultures of a hybridoma cell line, in: Biotechnology and Applied Biochemistry 40.
ELSA
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2003 | Konferenz - Vortrag | ELSA-ID: 7934
Frahm, Björn/Pörtner, Ralf (2003): Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies.
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2435
Frahm, Björn et. al. (2003): Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control, Heiligenstadt.
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2436
Kühn, K. et. al. (2003): Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells (= 10), Granada.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2902
Frahm, Björn/Pörtner, Ralf (2003): Fed-Batch-Kultivierungen tierischer Zellen – eine Herausforderung an eine modellgestützte, adaptive Steuerung.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2903
Hass, V. C. et. al. (2003): Ein strukturiertes Kompartiment-Modell zur Beschreibung der Kultivierung von Hybridomazellen als Teil einer adaptiven, modellgestützten Prozessführung.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2905
Frahm, Björn et. al. (2003): Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies.
ELSA
| Dateien verfügbar
2003 | Konferenz - Vortrag | ELSA-ID: 2906
Pörtner, Ralf et. al. (2003): Fed-Batch-Kultivierung tierischer Zellen – eine Herausforderung für eine adaptive, modellgestützte Steuerung.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2964
Frahm, Björn/Pörtner, Ralf (2003): CO2-off-gas measurement for animal cell culture processes.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2965
Frahm, Björn/Pörtner, Ralf (2003): Flexible fed-batch process control of animal cells.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2966
Kühn, K. et. al. (2003): Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells.
ELSA
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2343 |

Frahm, Björn et. al. (2003): Fed-Batch-Kultivierung tierischer Zellen - Eine Herausforderung zur adaptiven, modellbasierten Steuerung, in: Chemie Ingenieur Technik 75 (4), S. 457–460.
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2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2344 |

Frahm, Björn et. al. (2003): Improvement of a mammalian cell culture process by adaptive, model-based dialysis fed-batch cultivation and suppression of apoptosis, in: Bioprocess and Biosystems Engineering 26 (1), S. 1–10.
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2003 | Dissertation | ELSA-ID: 2393
Frahm, Björn (2003): Adaptive, modellgestützte Prozessführung von Suspensionskulturen tierischer Zellen, Norderstedt.
ELSA
2002 | Konferenzband - Beitrag | ELSA-ID: 2431
Frahm, Björn/Pörtner, Ralf (2002): Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen, Meinsberg .
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2897
Frahm, Björn/Pörtner, Ralf (2002): Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2898
Frahm, Björn/Pörtner, Ralf (2002): Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2899
Frahm, Björn/Pörtner, Ralf (2002): Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2900
Frahm, Björn et. al. (2002): Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control.
ELSA
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2340 |

Frahm, Björn et. al. (2002): Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement, in: Journal of Biotechnology 99 (2), S. 133–148.
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2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2341 |

Frahm, Björn et. al. (2002): Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Effective Fed-Batch Cultivation of Hybridoma Cells, in: Biotechnology Progress 18 (5), S. 1095–1103.
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| DOI
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2002 | Zeitschriftenaufsatz | ELSA-ID: 2342
Frahm, Björn/Pörtner, R. (2002): Reaktor-Abgasmessungen bei Zellkulturen, in: BIOforum 4, S. 179–180.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 7933
Frahm, Björn/Pörtner, Ralf (2001): Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2429
Hass, V. C. et. al. (2001): Model-Based Control of Hybridoma Cell Cultures.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2894
Hoffmann, M. et. al. (2001): Untersuchung verschiedener mathematischer Modelle in Hinblick auf ihre Eignung für die adaptive Prozessführung von Hybridoma Zellkulturen.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2895
Frahm, Björn/Pörtner, R. (2001): Arbeitsschwerpunkte TUHH, Bioprozess- und Bioverfahrenstechnik, Arbeitsgruppe Zellkulturtechnik.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2960
Frahm, Björn et. al. (2001): Adaptive modellgestützte Steuerung von Zellkulturprozessen.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2961
Lane, P. et. al. (2001): Design of Feeding Strategies for Fed-Batch Cultures of Animal Cells by the Method of Inequalities.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2962
Frahm, Björn et. al. (2001): Development of an automated, model-based, adaptive control for the effective cultivation of hybridoma cells.
ELSA
2001 | Konferenzband - Beitrag | ELSA-ID: 2963 |

Hass, V.C. et. al. (2001): Model-Based Control of Hybridoma Cell Cultures (= IFAC Proceedings Volumes / IFAC, International Federation of Automatic Control 34), Oxford.
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2000 | Konferenz - Vortrag | ELSA-ID: 2893
Anderelei, T. et. al. (2000): Online-Bestimmung der Sauerstofftransferrate (OTR) und der Kohlendioxidtransferrate (CTR) in geschüttelten Bioreaktoren.
ELSA
2000 | Konferenz - Poster | ELSA-ID: 2959
Hoffmann, M. et. al. (2000): Modellgestützte Prozessführung für Hybridoma-Kulturen mit Hilfe des Open-Loop-Feedback-Optimal (OLFO)- Algorithmus.
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168 Publikationen
2024 | Konferenz - Vortrag | ELSA-ID: 12021
Segermann, Jan u. a.: Die Rolle von ML-Modellen in der Lebensmitteltechnologie: Eine Fallstudie zur Sauerteigfermentation mit NIR-Spektroskopie, o. O. 2024.
ELSA
2024 | Konferenz - Vortrag | ELSA-ID: 12022
Luttmann, Mario u. a.: Erkenntnisse zur Nutzung von Photogrammmetrie für die Untersuchung des Bräunungsverhaltens von Weizenbrötchen, o. O. 2024.
ELSA
2024 | Konferenz - Poster | ELSA-ID: 12395
Müller, Carolin u. a.: Investigation of microbial spoilage in vegan foods, o. O. 2024.
ELSA
2024 | Konferenz - Poster | ELSA-ID: 12396
Gassenmeier, Veronika/Campolongo, Giovanni/Frahm, Björn: Dissolved Carbon Dioxide in Addition to Dissolved Oxygen for In-situ Monitoring of Hybridoma Cell Culture, o. O. 2024.
ELSA
2024 | Konferenz - Poster | ELSA-ID: 12397
Blome, André u. a.: Process optimization in baked goods production using inline sensors and objective product evaluation, o. O. 2024.
ELSA
2024 | Preprint | ELSA-ID: 12400 |

Ramm, Selina u. a.: Semi-automated vs. manual: Comparative study of cell culture counting methods using validation parameters, o. O. 2024.
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2024 | Konferenz - Poster | ELSA-ID: 10957
Reinhardt, Lena u. a.: Mycelium-based materials from residues of the regional wood industry, o. O. u. J. .
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11378
Gassenmeier, Veronika/Campolongo, Giovanni/Frahm, Björn: Real-time Monitoring of DCO2 in addition to DO, o. O. u. J. .
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11381
Hernández Rodriguez, Tanja u. a.: A systematic, model-based workflow for risk-based decision making in upstream development, o. O. u. J. .
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11382 |

Gassenmeier, Veronika u. a.: View on a mechanistic model of Chlorella vulgaris in shake flasks, o. O. u. J. .
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2023 | Konferenz - Vortrag | ELSA-ID: 11383
Hernández Rodriguez, Tanja u. a.: Model-assisted design strategies for bioprocesses – Advanced statistical methods in industrial upstream cell culture, o. O. 2023.
ELSA
2023 | Konferenzband - Beitrag | ELSA-ID: 11384 |

Müller, Carolin u. a.: Microbial spoilage in vegan foods, o. O. 2023.
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2023 | Konferenz - Poster | ELSA-ID: 11487 |

Ramm, Selina u. a.: Comparison of Preprocessing Methods of Dielectric Spectroscopy Data and the Effects on Linear Regression , o. O. u. J. .
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2023 | Konferenz - Poster | ELSA-ID: 10201 |

Hernández Rodriguez, Tanja u. a.: A systematic, model-based workflow for risk-based decision making in upstream development, o. O. 2023.
ELSA
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2023 | Konferenz - Vortrag | ELSA-ID: 11109
Blome, André u. a.: Untersuchung der räumlichen Verteilung von viskoelastischen Kenngrößen während der Weizenteigbereitung, o. O. 2023.
ELSA
2023 | Konferenz - Poster | ELSA-ID: 11110
Blome, André u. a.: Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, o. O. 2023.
ELSA
2023 | Konferenz - Poster | ELSA-ID: 12483
Blome, André u. a.: Vorstellung des Projektes „Teig 4.0“ - Prozessoptimierung im Bereich der industriellen Weizenteigverarbeitung, o. O. 2023.
ELSA
2023 | Konferenz - Poster | ELSA-ID: 12485
Luttmann, Mario u. a.: Teig 4.0 - Promotionsthemen, o. O. 2023.
ELSA
2023 | Konferenzband - Beitrag | ELSA-ID: 10788 |

Ramm, Selina u. a.: Systematic Preprocessing of Dielectric Spectroscopy Data and Estimating Viable Cell Densities, hg. von Jasperneite, Jürgen u. a., [Piscataway, NJ] 2023.
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2022 | Konferenz - Poster | ELSA-ID: 7932
Hernández Rodriguez, Tanja u. a.: A systematic, model-based workflow for risk-based decision making in upstream development, o. O. u. J. .
ELSA
2022 | Datenpublikation | ELSA-ID: 10190
Gassenmeier, Veronika/Frahm, Björn: Real-time Monitoring of DCO2 in addition to DO, o. O. 2022.
ELSA
| Dateien verfügbar
2022 | Sammelwerk - Beitrag | ELSA-ID: 10193
Hernández Rodriguez, Tanja u. a.: Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design, in: Pörtner, Ralf/Möller, Johannes (Hgg.): Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, Band special issue, Basel 2022 (Processes : open access journal), S. 21–48.
ELSA
| DOI
2022 | Konferenzband - Beitrag | ELSA-ID: 10195
Blome, André u. a.: Process optimisation in the field of wheat dough processing using real-time recording of quality-relevant characteristics in raw materials, intermediates and final products, o. O. 2022.
ELSA
2022 | Konferenz - Vortrag | ELSA-ID: 10196
Blome, André u. a.: Process optimisation in the field of wheat dough processing using real-time recording of quality-relevant characteristics in raw materials, intermediates and final products, o. O. 2022.
ELSA
2022 | Konferenz - Vortrag | ELSA-ID: 10197
Hernández Rodriguez, Tanja u. a.: Model assisted Design Strategies for Bioprocesses – Advanced statistical methods in industrial upstream cell culture, o. O. 2022.
ELSA
2022 | Konferenz - Poster | ELSA-ID: 10198
Hernández Rodriguez, Tanja u. a.: A systematic, model-based approach for decision making in upstream development – Considerations regarding clone selection and cell expansion, o. O. u. J. .
ELSA
2022 | Konferenz - Poster | ELSA-ID: 10199 |

Müller, Carolin u. a.: Microbial spoilage in vegan foods, o. O. 2022.
ELSA
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2021 | Konferenz - Vortrag | ELSA-ID: 7927
Hernández Rodriguez, Tanja/Frahm, Björn: Model-based methods in bioprocess technology - Bioprocess modeling, simulation and prediction, o. O. 2021.
ELSA
2021 | Konferenz - Poster | ELSA-ID: 7931
Moser, André et. al. (2021): Model-assisted Design of Experiments - Concept, Software and Applications.
ELSA
2021 | Lexikoneintrag | ELSA-ID: 7939
Wirtanen, Gun et. al. (2021): Bovine Colostrum for Human Consumption, in: MDPI Encyclopedia, Scholarly Community Encyclopedia, Category: Agriculture, Dairy & Animal Science.
ELSA
2021 | Sammelwerk - Beitrag | ELSA-ID: 7983
Hernández Rodriguez, Tanja u. a.: Considerations of the impacts of cell-specific growth and production rate on clone selection – a simulation study, in: o. Hg.: Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing, Band special issue, Basel 2021 (Processes : open access journal ), S. 49–74.
ELSA
| DOI
2021 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 7985
Hernández Rodriguez, Tanja u. a.: Dynamic parameter estimation and prediction over consecutive scales, based on moving horizon estimation - applied to an industrial cell culture seed train, in: Bioprocess and Biosystems Engineering 44 (2021), H. 4, S. 793–808.
ELSA
| DOI
2021 | Konferenz - Vortrag | ELSA-ID: 8078
Blome, André u. a.: Messtechnikkonzepte für die Erfassung von qualitätsrelevanten Parametern und Merkmalen bei der Weizenteigverarbeitung, o. O. 2021.
ELSA
2021 | Sammelwerk - Beitrag | ELSA-ID: 3349
Hernández Rodriguez, Tanja/Frahm, Björn: Digital Seed Train Twins and Statistical Methods, in: Herwig, Christoph/Pörtner, Ralf/Möller, Johannes (Hgg.): Digital Twins Tools and Concepts for Smart Biomanufacturing, Bd. 176, Berlin, Heidelberg 2021 (Advances in Biochemical Engineering/Biotechnology), S. 97–131.
ELSA
| DOI
2020 | Konferenz - Poster | ELSA-ID: 7929
Hernández Rodriguez, Tanja et. al. (2020): Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
2020 | Konferenz - Poster | ELSA-ID: 7930
Hernández Rodriguez, Tanja et. al. (2020): Towards integration of prior knowledge and propagation of uncertainty for digital twins of biopharmaceutical production processes.
ELSA
2020 | Konferenz - Vortrag | ELSA-ID: 7936
Hernández Rodriguez, Tanja et. al. (2020): Integration of prior knowledge and digital tools for uncertainty-based decision support.
ELSA
2020 | Konferenzband - Beitrag | ELSA-ID: 2822
Hernández Rodriguez, Tanja et. al. (2020): Predicting Industrial Cell Culture Seed Trains - A Bayesian Approach (= 14).
ELSA
| Dateien verfügbar
| DOI
2020 | Konferenz - Poster | ELSA-ID: 3007
Kuhfuß, F. et. al. (2020): Modeling of Chlorella vulgaris in shake flasks with respect to light intensity and light duration.
ELSA
2020 | Konferenz - Poster | ELSA-ID: 3008
Deppe, S. et. al. (2020): Model-assisted Design of Experiments for algae cultivation.
ELSA
2020 | Konferenz - Poster | ELSA-ID: 3009
Ifrim, George Adrian et. al. (2020): Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
2020 | Sammelwerk - Beitrag | ELSA-ID: 2397
Hernández Rodríguez, Tanja/Frahm, Björn (2020): Design, Optimization and Adaptive Control of Cell Culture Seed Trains, in: Ralf Pörtner (Hg.): Animal Cell Biotechnology - Methods and Protocols (=Methods in Molecular Biology 2095), Berlin, Heidelberg, New York, S. 251–267.
ELSA
| DOI
2019 | Konferenz - Vortrag | ELSA-ID: 2956
Möller, J. et. al. (2019): Workflow for model-assisted design and scale-up of biopharmaceutical production processes.
ELSA
2019 | Konferenz - Vortrag | ELSA-ID: 2957
Möller, J. et. al. (2019): Model-Assisted Design of Experiments.
ELSA
2019 | Konferenz - Vortrag | ELSA-ID: 2958
Ifrim, George Adrian et. al. (2019): Novel control strategy for microalgae in photobioreactor.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3000
Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3001
Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3002
Möller, J. et. al. (2019): Model-Assisted Design of Experiments – Software Toolbox.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3003
Deppe, S. et. al. (2019): Model-assisted Design of Experiments for algae cultivation.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3004
Ifrim, George Adrian et. al. (2019): Modeling of microalgae in an air-lift photobioreactor for biomass production.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3005
Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial scale cell culture seed trains – considerations of input uncertainty, new process data and prognostic intervals using a Bayesian approach and sequential Bayesian updating.
ELSA
2019 | Konferenz - Poster | ELSA-ID: 3006
Ifrim, George Adrian et. al. (2019): Multivariable control strategy for the photosynthetic cultures of microalgae.
ELSA
2019 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2391 |

Hernández Rodriguez, Tanja et. al. (2019): Predicting industrial‐scale cell culture seed trains–A Bayesian framework for model fitting and parameter estimation, dealing with uncertainty in measurements and model parameters, applied to a nonlinear kinetic cell culture model, using an MCMC method, in: Biotechnology and Bioengineering 116 (11), S. 2944–2959.
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2018 | Konferenz - Vortrag | ELSA-ID: 7935
Hernández Rodriguez, Tanja et. al. (2018): A model-assisted approach for design, optimization and control of bioprocesses – a software tool for seed train simulation and optimization.
ELSA
2018 | Konferenzband - Beitrag | ELSA-ID: 2821
Hernández Rodriguez, Tanja et. al. (2018): Model-assisted cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization (= 112).
ELSA
| Dateien verfügbar
| DOI
2018 | Konferenz - Vortrag | ELSA-ID: 2955
Pörtner, R. et. al. (2018): Model-Assisted Design of Process Strategies for Cell Culture Processes.
ELSA
2018 | Konferenz - Poster | ELSA-ID: 2997
Möller, J. et. al. (2018): Model-Assisted Design and Optimization of Process Strategies.
ELSA
2018 | Konferenz - Poster | ELSA-ID: 2999
Hernández Rodriguez, Tanja et. al. (2018): Model-Assisted Strategies for Design, Optimization and Control of Bioprocesses.
ELSA
2018 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2390 |

Möller, J. et. al. (2018): Model-Assisted Design of Process Strategies for Cell Culture Processes, in: American Pharmaceutical Review 3, S. 39–41.
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2017 | Konferenz - Vortrag | ELSA-ID: 2920
Hernández Rodriguez, Tanja et. al. (2017): Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
2017 | Konferenz - Vortrag | ELSA-ID: 2921
Pörtner, R. et. al. (2017): Model-assisted design and optimization of biotechnological processes.
ELSA
2017 | Konferenz - Vortrag | ELSA-ID: 2950
Hernández Rodriguez, Tanja et. al. (2017): Produktion von Biopharmazeutika – Ein MATLAB©-Tool zur Simulation und Optimierung von Zellvermehrungsverfahren.
ELSA
2017 | Konferenz - Poster | ELSA-ID: 2994
Hernández Rodriguez, Tanja et. al. (2017): Influence of parameter accuracies in cell culture seed train simulations.
ELSA
2017 | Konferenz - Poster | ELSA-ID: 2995
Hernández Rodriguez, Tanja et. al. (2017): Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
2017 | Konferenz - Poster | ELSA-ID: 2996
Hernández Rodriguez, Tanja et. al. (2017): Model-based cell culture control – unstructured, unsegregated models as a key element for adaptive seed train and fed-batch optimization.
ELSA
2016 | Konferenz - Poster | ELSA-ID: 2991
Beshay, U. et. al. (2016): DMA Photobioreactor System – Cultivation at low shear stress and optional membrane aeration.
ELSA
2016 | Konferenz - Poster | ELSA-ID: 2992
Hernández Rodriguez, Tanja et. al. (2016): A software tool for biopharmaceutical seed train design and optimization.
ELSA
2016 | Konferenz - Poster | ELSA-ID: 2993
Koopmann, K. S. et. al. (2016): Simulation of cell culture seed trains – investigation of the influence of parameter inaccuracies.
ELSA
2015 | Konferenzband - Beitrag | ELSA-ID: 2819 |

Hernández Rodriguez, Tanja et. al. (2015): Considerations for cell passaging in cell culture seed trains (= 9).
ELSA
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2015 | Konferenzband - Beitrag | ELSA-ID: 2820 |

Kern, Simon et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale (= 9).
ELSA
| DOI
| Download (ext.)
2015 | Konferenz - Vortrag | ELSA-ID: 2917
Frahm, Björn et. al. (2015): Seed train design and optimization for animal cell suspension culture.
ELSA
| Dateien verfügbar
2015 | Konferenz - Vortrag | ELSA-ID: 2919
Frahm, Björn et. al. (2015): Seed train design and optimization for animal cell suspension culture.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2985
Hernández Rodriguez, Tanja et. al. (2015): Considerations for cell passaging in cell culture seed trains.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2986
Kern, S. et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2987
Hernández Rodriguez, Tanja et. al. (2015): A software tool for biopharmaceutical seed train design and optimization.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2988
Hernández Rodriguez, Tanja et. al. (2015): Considerations for cell passaging in cell culture seed trains.
ELSA
2015 | Konferenz - Poster | ELSA-ID: 2990
Kern, S. et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale.
ELSA
2015 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2389
Kern, Simon et. al. (2015): Model-based strategy for cell culture seed train layout verified at lab scale, in: Cytotechnology 68 (4), S. 1019–1032.
ELSA
| DOI
| Download (ext.)
2014 | Patent | ELSA-ID: 2878
Frahm, Björn/Meier, Uwe (2014): Beleuchtung von disposable Bioreaktoren.
ELSA
2014 | Konferenz - Poster | ELSA-ID: 2984
Drews, F. et. al. (2014): Herstellung von Paramylon mit Euglena gracilis im disposable Bag mit LED-Beleuchtung direkt auf dessen Oberfläche.
ELSA
2014 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2388
Hahne, T. et. al. (2014): Disposable algae cultivation for high-value products using all around LED-illumination directly on the bags, in: Journal of Algal Biomass Utilization 5 (2), S. 66–73.
ELSA
2013 | Konferenzband - Beitrag | ELSA-ID: 2817 |

Hernández Rodriguez, Tanja et. al. (2013): Seed train optimization for suspension cell culture (= 7).
ELSA
| DOI
| Download (ext.)
2013 | Konferenzband - Beitrag | ELSA-ID: 2818 |

Kern, Simon et. al. (2013): Model-based design of the first steps of a seed train for cell culture processes (= 7).
ELSA
| DOI
| Download (ext.)
2013 | Konferenz - Poster | ELSA-ID: 2980
Kern, S. et. al. (2013): Modellgestützte Auslegung der ersten Schritte eines Seed-Trains für Zellkulturprozesse.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2981
Kern, S. et. al. (2013): Model-based design of the first steps of a seed train for cell culture processes.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2982
Hahne, T. et. al. (2013): Disposable Algenkultivierung für hochpreisige Produkte mittels LED-Rundumbeleuchtung direkt auf den Bags.
ELSA
2013 | Konferenz - Poster | ELSA-ID: 2983
Hernández Rodriguez, Tanja et. al. (2013): Seed train optimization for suspension cell culture.
ELSA
2012 | Konferenzband - Beitrag | ELSA-ID: 2816 |

Frahm, Björn/Brod, H. (2012): Improving Cell Culture Bioreactor Performance for Sensitive Cell Lines by Dynamic Membrane Aeration (DMA) (=ESACT Proceedings 5), Dordrecht.
ELSA
| DOI
| Download (ext.)
2012 | Patent | ELSA-ID: 2877
Brod, Helmut/Frahm, Björn (2012): Photobioreaktor mit rotatorisch oszillierenden Lichtquellen.
ELSA
2012 | Konferenz - Vortrag | ELSA-ID: 2918
Van Hecke, W. et. al. (2012): Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor.
ELSA
2012 | Konferenz - Poster | ELSA-ID: 2973
Marzougui, R. et. al. (2012): Optimierung des Seed trains von Suspensions-Zellkulturen.
ELSA
2011 | Konferenz - Poster | ELSA-ID: 2972
Van Hecke, W. et. al. (2011): Modelling and upscaling of a biocatalytic cascade oxidation in a dynamic membrane aeration reactor.
ELSA
2011 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2350
Van Hecke, Wouter et. al. (2011): A biocatalytic cascade reaction sensitive to the gas–liquid interface: Modeling and upscaling in a dynamic membrane aeration reactor, in: Journal of Molecular Catalysis B: Enzymatic 68 (2), S. 154–161.
ELSA
| DOI
| Download (ext.)
2010 | Konferenzband - Beitrag | ELSA-ID: 2815
Dercks, B. et. al. (2010): Intensified absorption and distillation devices for modular chemical production processes.
ELSA
2010 | Patent | ELSA-ID: 2873
Brod, Helmut et. al. (2010): Verfahren zur Reduzierung von Ablagerungen bei der Kultivierung von Organismen.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2892
Frahm, Björn/Brod, Helmut (2010): Cultivation of sensitive cell lines - Improving bioreactor performance by Dynamic Membrane Aeration.
ELSA
2010 | Konferenz - Vortrag | ELSA-ID: 2913
Dercks, B. et. al. (2010): Intensified absorption and distillation devices for modular chemical production processes.
ELSA
2009 | Patent | ELSA-ID: 2872
Braun, Arndt et. al. (2009): Verfahren und Vorrichtung zur Rückhaltung und Rückführung von Zellen.
ELSA
2009 | Konferenz - Vortrag | ELSA-ID: 2912
Frahm, Björn et. al. (2009): Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA).
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2970
Frahm, Björn et. al. (2009): Improving cell culture bioreactor performance by Dynamic Membrane Aeration (DMA).
ELSA
2009 | Konferenz - Poster | ELSA-ID: 2971
Van Hecke, W. et. al. (2009): Upscaling the biocatalytic conversion of lactose to lactobionic acid with the dynamic membrane aeration reactor.
ELSA
2009 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2349 |

Frahm, Björn et. al. (2009): Improving bioreactor cultivation conditions for sensitive cell lines by dynamic membrane aeration, in: Cytotechnology 59 (1), S. 17–30.
ELSA
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2008 | Konferenz - Vortrag | ELSA-ID: 2911
Brod, H. et. al. (2008): Pushing the Limits in High-Density Mammalian Cell Fermentation.
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2968
Frahm, Björn et. al. (2008): High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA).
ELSA
2008 | Konferenz - Poster | ELSA-ID: 2969
Frahm, Björn/Brod, Helmut (2008): High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA).
ELSA
2007 | Patent | ELSA-ID: 2870 |

Brod, Helmut et. al. (2007): Procedure for gassing of liquid for cell cultures, comprises exchanging of gas over immersed membrane surfaces and controlling the gassing rate change of the gas concentration and/or pressure of the gas or gas mixture or gas component.
ELSA
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2007 | Patent | ELSA-ID: 2871
Brod, Helmut et. al. (2007): Verfahren und Vorrichtung zur Be- und Entgasung von Flüssigkeiten, insbesondere in der Biotechnologie und speziell von Zellkulturen.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2909
Brod, Helmut et. al. (2007): Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen.
ELSA
2007 | Konferenz - Vortrag | ELSA-ID: 2910
Brod, Helmut et. al. (2007): Die dynamische Membranbegasung – ein Ansatz zur Intensivierung der Sauerstoffversorgung tierischer Zellkulturen.
ELSA
2007 | Konferenz - Poster | ELSA-ID: 2967
Frahm, Björn et. al. (2007): High cell density bioreactor cultivation by Dynamic Membrane Aeration (DMA).
ELSA
2007 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2348
Frahm, Björn et. al. (2007): Dynamische Membranbegasung im Bioreaktor zur Intensivierung der Sauerstoffversorgung empfindlicher Zelllinien, in: Chemie Ingenieur Technik 79 (7), S. 1052–1058.
ELSA
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2005 | Konferenz - Vortrag | ELSA-ID: 2907
Pörtner, Ralf et. al. (2005): Optimisation of time-space-yield for hybridoma fed-batch cultures with an adaptive OLFO-controller.
ELSA
2005 | Konferenz - Vortrag | ELSA-ID: 2908
Pörtner, R. et. al. (2005): Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode.
ELSA
2005 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2347 |

Frahm, Björn et. al. (2005): Optimierung und Steuerung von Zellkultur-Fed-Batch-Prozessen mittels einer Kollokationsmethode, in: Chemie Ingenieur Technik 77 (4), S. 429–435.
ELSA
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2004 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2345 |

Pörtner, Ralf et. al. (2004): Evaluation of selected control strategies for fed-batch cultures of a hybridoma cell line, in: Biotechnology and Applied Biochemistry 40.
ELSA
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2003 | Konferenz - Vortrag | ELSA-ID: 7934
Frahm, Björn/Pörtner, Ralf (2003): Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies.
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2435
Frahm, Björn et. al. (2003): Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control, Heiligenstadt.
ELSA
2003 | Konferenzband - Beitrag | ELSA-ID: 2436
Kühn, K. et. al. (2003): Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells (= 10), Granada.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2902
Frahm, Björn/Pörtner, Ralf (2003): Fed-Batch-Kultivierungen tierischer Zellen – eine Herausforderung an eine modellgestützte, adaptive Steuerung.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2903
Hass, V. C. et. al. (2003): Ein strukturiertes Kompartiment-Modell zur Beschreibung der Kultivierung von Hybridomazellen als Teil einer adaptiven, modellgestützten Prozessführung.
ELSA
2003 | Konferenz - Vortrag | ELSA-ID: 2905
Frahm, Björn et. al. (2003): Fed-batch-cultivation of animal cells: Model-based, adaptive control in comparison to alternative control strategies.
ELSA
| Dateien verfügbar
2003 | Konferenz - Vortrag | ELSA-ID: 2906
Pörtner, Ralf et. al. (2003): Fed-Batch-Kultivierung tierischer Zellen – eine Herausforderung für eine adaptive, modellgestützte Steuerung.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2964
Frahm, Björn/Pörtner, Ralf (2003): CO2-off-gas measurement for animal cell culture processes.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2965
Frahm, Björn/Pörtner, Ralf (2003): Flexible fed-batch process control of animal cells.
ELSA
2003 | Konferenz - Poster | ELSA-ID: 2966
Kühn, K. et. al. (2003): Adaptive, Model-based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Cultivation of Hybridoma Cells.
ELSA
2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2343 |

Frahm, Björn et. al. (2003): Fed-Batch-Kultivierung tierischer Zellen - Eine Herausforderung zur adaptiven, modellbasierten Steuerung, in: Chemie Ingenieur Technik 75 (4), S. 457–460.
ELSA
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2003 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2344 |

Frahm, Björn et. al. (2003): Improvement of a mammalian cell culture process by adaptive, model-based dialysis fed-batch cultivation and suppression of apoptosis, in: Bioprocess and Biosystems Engineering 26 (1), S. 1–10.
ELSA
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2003 | Dissertation | ELSA-ID: 2393
Frahm, Björn (2003): Adaptive, modellgestützte Prozessführung von Suspensionskulturen tierischer Zellen, Norderstedt.
ELSA
2002 | Konferenzband - Beitrag | ELSA-ID: 2431
Frahm, Björn/Pörtner, Ralf (2002): Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen, Meinsberg .
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2897
Frahm, Björn/Pörtner, Ralf (2002): Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2898
Frahm, Björn/Pörtner, Ralf (2002): Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2899
Frahm, Björn/Pörtner, Ralf (2002): Adaptive, model-based control by the OLFO-controller for the fed-batch cultivation of animal cells.
ELSA
2002 | Konferenz - Vortrag | ELSA-ID: 2900
Frahm, Björn et. al. (2002): Fed-batch cultivation of animal cells - a challenge for adaptive, model-based control.
ELSA
2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2340 |

Frahm, Björn et. al. (2002): Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement, in: Journal of Biotechnology 99 (2), S. 133–148.
ELSA
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2002 | Zeitschriftenaufsatz (wiss.) | ELSA-ID: 2341 |

Frahm, Björn et. al. (2002): Adaptive, Model-Based Control by the Open-Loop-Feedback-Optimal (OLFO) Controller for the Effective Fed-Batch Cultivation of Hybridoma Cells, in: Biotechnology Progress 18 (5), S. 1095–1103.
ELSA
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2002 | Zeitschriftenaufsatz | ELSA-ID: 2342
Frahm, Björn/Pörtner, R. (2002): Reaktor-Abgasmessungen bei Zellkulturen, in: BIOforum 4, S. 179–180.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 7933
Frahm, Björn/Pörtner, Ralf (2001): Messung und Simulation des Kohlendioxidausstoßes von Zellkulturprozessen.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2429
Hass, V. C. et. al. (2001): Model-Based Control of Hybridoma Cell Cultures.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2894
Hoffmann, M. et. al. (2001): Untersuchung verschiedener mathematischer Modelle in Hinblick auf ihre Eignung für die adaptive Prozessführung von Hybridoma Zellkulturen.
ELSA
2001 | Konferenz - Vortrag | ELSA-ID: 2895
Frahm, Björn/Pörtner, R. (2001): Arbeitsschwerpunkte TUHH, Bioprozess- und Bioverfahrenstechnik, Arbeitsgruppe Zellkulturtechnik.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2960
Frahm, Björn et. al. (2001): Adaptive modellgestützte Steuerung von Zellkulturprozessen.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2961
Lane, P. et. al. (2001): Design of Feeding Strategies for Fed-Batch Cultures of Animal Cells by the Method of Inequalities.
ELSA
2001 | Konferenz - Poster | ELSA-ID: 2962
Frahm, Björn et. al. (2001): Development of an automated, model-based, adaptive control for the effective cultivation of hybridoma cells.
ELSA
2001 | Konferenzband - Beitrag | ELSA-ID: 2963 |

Hass, V.C. et. al. (2001): Model-Based Control of Hybridoma Cell Cultures (= IFAC Proceedings Volumes / IFAC, International Federation of Automatic Control 34), Oxford.
ELSA
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2000 | Konferenz - Vortrag | ELSA-ID: 2893
Anderelei, T. et. al. (2000): Online-Bestimmung der Sauerstofftransferrate (OTR) und der Kohlendioxidtransferrate (CTR) in geschüttelten Bioreaktoren.
ELSA
2000 | Konferenz - Poster | ELSA-ID: 2959
Hoffmann, M. et. al. (2000): Modellgestützte Prozessführung für Hybridoma-Kulturen mit Hilfe des Open-Loop-Feedback-Optimal (OLFO)- Algorithmus.
ELSA